Hub : Genes

Atg16l2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Atg16l2 0.04 0.03 1.8e-03 0.02 0.01 0.02 0.01 2.4e-03 1.1e-02 4.5e-03 1.3e-02
2 Eye alternative TSS XM_006229877.4 0.45 0.24 8.9e-03 0.13 0.04 0.17 0.12 5.1e-03 9.0e-02 1.4e-03 6.2e-03
3 Eye alternative TSS XM_006229877.4 0.47 0.25 7.5e-03 0.13 0.03 0.17 0.13 5.1e-03 1.0e-01 1.3e-03 5.1e-03
4 Adipose gene expression Atg16l2 0.05 0.03 1.7e-05 0.03 0.04 0.03 0.03 2.0e-04 6.2e-05 3.5e-04 5.2e-04
5 Liver intron excision ratio chr1_155701366_155703063 0.28 0.14 5.9e-15 0.07 0.1 0.09 0.1 1.7e-08 1.1e-11 1.5e-10 1.3e-11
6 Liver intron excision ratio chr1_155708732_155710770 0.41 0.16 0.0e+00 0.12 0.15 0.14 0.15 2.9e-13 6.3e-16 6.3e-15 6.3e-16
7 Brain gene expression Atg16l2 0.04 0.03 1.5e-03 0.01 0.03 0.02 0.02 1.5e-02 8.3e-04 2.4e-03 1.1e-02
8 NAcc alternative polyA NM_001191560.1 0.02 0.01 4.0e-03 0.02 0.01 0.01 0.01 2.8e-03 6.1e-03 6.8e-03 9.2e-03
9 NAcc alternative polyA NM_001191560.1 0.02 0.01 7.8e-03 0.02 0.01 0.01 0.02 4.3e-03 7.4e-03 8.7e-03 4.9e-03
10 NAcc alternative polyA XM_039113327.1 0.02 0.01 4.9e-03 0.02 0.01 0.01 0.02 2.7e-03 6.0e-03 8.5e-03 3.1e-03
11 NAcc alternative polyA XM_039113327.1 0.02 0.01 2.4e-03 0.02 0.02 0.02 0.02 1.3e-03 5.5e-03 3.7e-03 5.1e-03
12 Brain alternative TSS XM_006229877.4 0.06 0.03 2.0e-04 0.05 0.04 0.04 0.04 2.8e-05 5.2e-05 5.9e-05 7.1e-05
13 Brain alternative TSS XM_006229877.4 0.06 0.03 1.8e-04 0.05 0.05 0.04 0.04 3.1e-05 4.2e-05 6.0e-05 7.4e-05
14 BLA gene expression Atg16l2 0.35 0.13 5.2e-10 0.17 0.13 0.15 0.15 1.6e-09 2.1e-07 2.8e-08 1.3e-08
15 PL gene expression Atg16l2 0.16 0.08 4.2e-14 0.14 0.12 0.13 0.13 1.3e-14 1.6e-13 3.8e-14 4.6e-14
16 NAcc gene expression Atg16l2 0.05 0.03 3.4e-04 0.02 0.02 0.02 0.01 3.3e-03 1.8e-03 5.5e-03 1.4e-02
17 BLA alternative polyA NM_001191560.1 0.1 0.07 1.5e-03 0.03 0.05 0.05 0.04 1.7e-02 1.4e-03 1.5e-03 4.6e-03
18 BLA alternative polyA XM_039113327.1 0.12 0.07 6.0e-04 0.02 0.05 0.05 0.04 2.2e-02 1.4e-03 1.6e-03 5.6e-03
19 BLA alternative polyA NM_001191560.1 0.12 0.07 4.0e-04 0.02 0.05 0.05 0.04 2.3e-02 1.0e-03 1.2e-03 4.2e-03
20 OFC alternative TSS XM_039113327.1 0.2 0.1 1.3e-03 0.05 0.08 0.05 0.06 2.1e-02 5.5e-03 2.2e-02 2.0e-02
21 OFC alternative TSS XM_039113327.1 0.19 0.1 1.3e-03 0.05 0.08 0.05 0.05 2.4e-02 5.2e-03 2.2e-02 2.4e-02
22 BLA alternative polyA XM_039113327.1 0.09 0.06 1.9e-03 0.02 0.05 0.05 0.04 2.0e-02 1.4e-03 1.2e-03 4.4e-03
23 PL isoform ratio NM_001191560.1 0.11 0.07 1.5e-05 0.05 0.05 0.07 0.06 1.8e-06 3.7e-06 2.4e-08 8.4e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.30.51.3-0.60.10.20.1-1.00.90.50.10.1-0.1-0.1-1.2-1.2-1.1-1.10.50.6-0.70.7-0.6-0.60.9-0.3
Area under the delay curve0.40.41.0-0.51.00.91.0-0.60.5-0.20.90.9-0.9-0.9-0.3-0.3-0.1-0.1-0.5-0.70.6-0.60.60.6-0.30.9
BMI with tail0.41.24.1-0.81.51.5-0.8-0.31.11.7-1.2-1.21.21.2-0.7-0.7-0.8-0.82.00.7-0.80.8-1.3-1.30.6-0.9
BMI without tail0.61.23.60.5-1.1-1.2-0.81.9-1.3-0.9-0.9-0.90.90.91.51.51.41.4-0.3-0.91.0-1.00.70.7-1.1-0.3
Body weight0.83.36.80.8-1.2-1.30.32.3-2.0-1.80.40.4-0.4-0.42.52.52.62.6-1.7-2.12.3-2.32.12.1-2.41.0
Weight adjusted by age0.60.72.00.8-0.7-0.7-0.51.4-1.3-1.0-0.6-0.60.60.61.01.01.11.1-0.6-0.60.7-0.70.70.7-0.60.3
Bone surface0.20.42.11.2-1.5-1.4-0.50.6-0.7-1.2-0.2-0.20.20.20.30.30.20.2-0.90.10.0-0.00.40.40.20.2
Bone volume0.20.30.90.9-0.9-0.9-0.20.5-0.7-1.00.00.0-0.0-0.00.30.30.30.3-0.9-0.00.2-0.20.50.50.00.4
Breakpoint value in progressive ratio session0.40.51.0-0.80.40.4-0.4-0.40.51.0-0.7-0.70.70.7-0.4-0.4-0.4-0.41.00.8-0.80.8-0.9-0.90.6-1.0
Number of licking bursts1.61.95.6-2.41.81.82.2-1.41.51.21.71.7-1.7-1.7-1.0-1.0-0.5-0.50.5-1.31.0-1.00.40.5-1.00.7
Context. condit. distance diff. score1.51.85.01.6-1.7-1.7-2.21.5-1.5-0.7-1.9-1.91.91.90.70.70.70.70.01.4-1.11.1-0.8-0.80.9-1.1
Locomotion velocity, session 11.61.72.8-0.80.80.8-0.5-1.21.41.6-0.8-0.80.80.8-1.6-1.6-1.6-1.61.71.3-1.41.5-1.6-1.61.4-1.3
Locomotion distance, session 11.11.42.80.9-0.5-0.5-1.60.10.20.5-1.7-1.71.71.7-0.6-0.6-0.6-0.61.01.5-1.51.4-1.3-1.41.3-1.6
Locomotion velocity, session 20.40.52.20.7-0.3-0.3-1.00.10.20.5-0.9-0.90.90.9-0.2-0.2-0.5-0.50.80.7-0.70.7-0.8-0.80.6-1.5
Locomotion distance, session 20.50.71.80.8-0.1-0.1-1.30.4-0.00.5-1.3-1.31.31.30.00.0-0.2-0.20.81.0-0.90.9-0.9-0.90.7-1.3
Locomotion velocity, session 30.30.40.90.9-0.9-0.8-0.90.3-0.5-0.3-0.7-0.70.70.70.20.2-0.2-0.2-0.10.9-0.80.8-0.5-0.50.7-0.5
Locomotion distance, session 31.01.12.30.7-1.0-1.0-1.40.1-0.2-0.0-1.3-1.31.31.3-0.5-0.5-0.8-0.80.41.5-1.41.4-1.1-1.11.4-1.1
Stereotopy head waving bouts, day 30.70.81.50.30.00.00.90.4-0.5-0.61.01.0-1.0-1.00.80.80.70.7-0.9-1.21.2-1.21.11.1-1.20.8
Stereotopy head waving duration, day 30.10.10.30.5-0.2-0.2-0.50.2-0.10.1-0.5-0.50.50.5-0.2-0.2-0.3-0.30.30.5-0.40.4-0.4-0.40.3-0.5
Locomotion velocity, session 70.40.41.0-0.50.70.7-0.3-0.40.50.9-0.6-0.60.60.6-0.4-0.4-0.4-0.41.00.6-0.70.7-0.8-0.80.5-0.3
Locomotion distance, session 70.20.30.9-0.40.90.90.6-0.10.00.10.60.6-0.6-0.60.30.30.20.2-0.2-0.50.5-0.50.40.4-0.50.9
Stereotopy head waving bouts, day 71.61.85.01.9-2.2-2.2-2.01.0-1.0-0.9-1.7-1.71.71.7-0.0-0.0-0.1-0.1-0.11.4-1.21.2-0.7-0.71.1-1.3
Stereotopy head waving duration, day 71.92.37.02.0-2.6-2.6-2.31.1-1.0-0.9-1.9-1.91.91.9-0.0-0.0-0.1-0.1-0.01.5-1.21.2-0.8-0.81.2-1.7
Locomotion velocity, session 80.60.82.01.4-1.4-1.4-1.21.1-1.2-0.8-0.9-0.90.90.90.70.70.70.7-0.40.6-0.40.4-0.1-0.10.1-0.5
Locomotion distance, session 81.52.25.91.8-1.7-1.7-2.41.7-1.4-0.6-2.1-2.12.12.10.90.90.60.60.11.4-1.11.1-0.8-0.80.9-1.6
Degree of sensitization distance2.82.85.50.10.50.51.41.0-1.0-1.01.61.6-1.6-1.61.81.82.02.0-1.5-2.32.2-2.22.02.0-2.31.8
Degree of sensitization stereotypy3.03.38.82.5-3.0-2.9-2.81.5-1.6-1.3-2.4-2.42.42.40.30.30.20.2-0.31.9-1.51.5-0.9-0.91.4-1.6
Conditioned locomotion0.70.81.8-0.40.70.71.1-0.1-0.3-0.31.31.3-1.3-1.30.70.70.50.5-1.0-0.80.8-0.80.90.9-0.71.4
Cocaine response after cond. corrected0.50.62.5-1.61.11.11.3-0.60.80.60.80.8-0.8-0.8-0.1-0.1-0.1-0.10.3-1.00.8-0.80.40.4-0.80.6
Cocaine response after cond. not corrected0.30.41.3-1.10.70.70.3-0.81.01.0-0.1-0.10.10.1-0.7-0.7-0.7-0.71.00.0-0.20.2-0.5-0.50.2-0.3
Cocaine response before conditioning2.12.54.91.1-1.0-1.0-2.2-0.00.20.5-2.0-2.02.02.0-1.0-1.0-1.2-1.21.32.2-2.12.1-1.9-1.92.1-1.9
Saline control response2.12.76.92.6-2.2-2.2-0.52.0-2.2-2.40.10.1-0.1-0.12.12.12.02.0-2.2-0.81.0-1.11.51.5-1.00.7
Bone: connectivity density1.42.24.0-0.50.10.1-0.9-1.31.51.3-1.0-1.01.01.0-2.0-2.0-2.0-2.01.71.7-1.81.7-1.8-1.81.9-1.5
Bone: cortical apparent density1.31.73.5-1.21.31.31.9-0.20.20.11.61.6-1.6-1.60.80.80.70.7-0.6-1.71.6-1.61.31.3-1.71.7
Bone: cortical area0.60.91.81.1-0.8-0.90.01.1-1.2-1.30.20.2-0.2-0.21.31.31.31.3-1.3-0.80.9-0.91.11.1-0.90.7
Bone: cortical porosity0.20.20.90.5-0.6-0.5-0.3-0.40.1-0.3-0.0-0.00.00.0-0.6-0.6-0.5-0.5-0.30.7-0.70.6-0.3-0.30.9-0.2
Bone: cortical porosity0.10.20.60.5-0.5-0.5-0.2-0.30.0-0.30.00.0-0.0-0.0-0.5-0.5-0.3-0.3-0.40.6-0.60.6-0.2-0.20.80.0
Bone: cortical thickness0.10.10.6-0.20.80.70.1-0.30.40.6-0.1-0.10.10.1-0.1-0.1-0.1-0.10.50.1-0.10.2-0.3-0.30.1-0.2
Bone: cortical thickness0.00.00.20.50.40.4-0.00.1-0.2-0.1-0.0-0.00.00.00.30.30.20.2-0.30.0-0.00.00.10.10.10.4
Bone: cortical tissue density1.21.63.4-1.21.41.41.9-0.30.20.11.61.6-1.6-1.60.70.70.70.7-0.5-1.71.5-1.51.21.2-1.71.7
Condit. Reinf. active minus inactive responses1.21.32.31.0-0.8-0.80.31.1-1.4-1.40.40.4-0.4-0.41.51.51.51.5-1.5-1.11.2-1.21.31.3-1.31.2
Condit. Reinf. active-inactive response ratio1.81.93.71.1-1.3-1.30.41.3-1.6-1.90.60.6-0.6-0.61.61.61.81.8-1.9-1.21.4-1.41.61.6-1.31.4
Condit. Reinf. active responses0.70.91.80.6-0.2-0.20.80.5-0.8-1.00.80.8-0.8-0.81.11.11.01.0-1.3-1.11.1-1.11.21.3-1.11.1
Condit. Reinf. inactive responses0.10.10.6-0.20.80.80.5-0.50.50.40.50.5-0.5-0.5-0.2-0.2-0.4-0.40.1-0.10.1-0.10.00.00.00.1
Incentive salience index mean0.70.91.81.0-0.6-0.60.40.7-0.9-1.20.50.5-0.5-0.51.11.11.11.1-1.3-0.91.0-1.01.21.2-0.90.9
Condit. Reinf. lever presses0.00.10.40.6-0.4-0.30.1-0.30.3-0.20.20.2-0.2-0.2-0.1-0.1-0.2-0.2-0.2-0.00.0-0.00.10.10.3-0.4
Condit. Reinf. active minus inactive responses4.45.516.54.1-3.8-3.8-2.23.3-3.3-3.2-1.4-1.41.41.42.72.72.62.6-2.2-0.10.6-0.61.21.2-0.7-0.4
Condit. Reinf. active-inactive response ratio0.90.92.91.6-1.7-1.7-1.41.1-1.0-1.0-1.0-1.01.01.00.80.80.60.6-0.40.5-0.30.3-0.1-0.10.3-0.7
Condit. Reinf. active responses6.08.324.65.0-4.4-4.4-2.34.1-4.1-4.0-1.3-1.31.31.33.43.43.43.4-3.0-0.61.2-1.21.91.8-1.1-0.2
Condit. Reinf. inactive responses4.04.914.23.8-3.0-3.0-1.23.0-3.1-3.1-0.5-0.50.50.52.72.72.72.7-2.6-0.91.4-1.41.91.9-1.20.2
Condit. Reinf. lever presses7.710.433.75.8-5.2-5.2-4.14.4-4.2-3.8-3.1-3.13.13.13.03.03.03.0-2.31.0-0.30.20.70.60.2-1.5
Condit. Reinf. lever reinforcers received6.28.726.95.2-4.8-4.8-2.64.0-4.0-4.0-1.6-1.61.61.63.33.33.43.4-3.0-0.30.9-0.91.71.6-0.8-0.6
Conditioned reinforcement - actives0.60.62.51.6-0.4-0.4-1.0-0.10.1-0.2-1.0-1.01.01.0-0.3-0.3-0.2-0.20.11.1-1.01.0-0.7-0.71.1-0.3
Conditioned reinforcement - inactives0.50.61.30.00.30.31.1-0.20.1-0.40.90.9-0.9-0.90.50.50.50.5-0.8-1.01.0-1.01.01.0-0.81.1
Conditioned locomotion1.62.04.41.5-0.3-0.3-1.90.1-0.00.1-2.1-2.12.12.1-0.7-0.7-0.8-0.80.71.9-1.81.8-1.4-1.41.8-1.2
Patch foraging indifference point 0 sec0.91.44.82.2-1.5-1.5-1.91.5-1.4-1.1-1.6-1.61.61.60.70.70.50.5-0.50.9-0.60.6-0.2-0.20.7-0.5
Patch foraging indifference point AUC0.60.71.20.8-0.4-0.40.11.1-1.1-1.00.40.4-0.4-0.40.90.90.80.8-0.9-1.01.0-1.01.01.0-1.00.8
Delay disc. indifference point, 0s delay0.20.20.90.9-0.5-0.5-0.50.8-0.8-0.7-0.2-0.20.20.20.60.60.50.5-0.6-0.00.2-0.20.30.3-0.1-0.0
Delay disc. indifference point, 16s delay0.70.72.2-1.00.70.71.3-0.60.1-0.31.21.2-1.2-1.20.00.00.10.1-0.9-0.80.7-0.70.80.9-0.51.5
Delay disc. indifference point, 2s delay0.50.61.90.9-0.5-0.50.00.8-0.8-1.4-0.0-0.00.00.00.80.80.80.8-1.3-0.70.8-0.81.01.0-0.70.7
Delay disc. indifference point, 24s delay1.01.02.9-1.71.61.61.7-0.90.60.31.11.1-1.1-1.10.10.10.20.2-0.4-0.90.8-0.80.70.7-0.81.4
Delay disc. indifference point, 4s delay1.11.12.31.2-0.6-0.60.01.3-1.3-1.50.30.3-0.3-0.31.31.31.31.3-1.4-1.01.1-1.11.31.3-1.00.5
Delay disc. indifference point, 8s delay0.20.21.0-0.01.01.00.5-0.60.50.10.50.5-0.5-0.5-0.5-0.5-0.3-0.3-0.1-0.20.1-0.10.10.20.20.6
Indifference point function ln k0.70.92.40.3-0.1-0.1-1.0-0.60.40.4-1.1-1.11.11.1-0.8-0.8-0.7-0.70.61.6-1.51.5-1.2-1.21.4-0.6
Indifference point function log k0.70.92.40.3-0.1-0.1-1.0-0.60.40.4-1.1-1.11.11.1-0.8-0.8-0.7-0.70.61.6-1.51.5-1.2-1.21.4-0.6
Patch foraging total patch changes 0 sec0.71.24.02.0-1.2-1.2-1.81.3-1.2-0.9-1.5-1.51.51.50.70.70.40.4-0.30.8-0.60.6-0.2-0.30.7-0.5
Patch foraging total patch changes 12 sec1.11.53.11.6-1.0-1.0-0.31.8-1.7-1.6-0.0-0.00.00.01.71.71.41.4-1.5-1.01.2-1.21.31.3-1.10.7
Patch foraging total patch changes 18 sec0.40.53.51.9-0.9-0.9-0.91.1-1.1-1.1-0.4-0.40.40.40.70.70.40.4-0.70.00.1-0.10.40.30.10.2
Patch foraging total patch changes 24 sec1.11.32.91.7-0.8-0.8-0.41.7-1.7-1.6-0.1-0.10.10.11.41.41.21.2-1.3-0.91.1-1.11.21.2-1.11.0
Patch foraging total patch changes 6 sec0.20.20.70.8-0.2-0.2-0.80.8-0.7-0.3-0.8-0.80.80.80.30.3-0.0-0.0-0.00.4-0.30.3-0.2-0.20.2-0.0
Patch foraging time to switch 0 sec1.52.36.5-2.52.12.12.2-2.22.01.61.91.9-1.9-1.9-1.3-1.3-1.3-1.30.8-0.60.3-0.2-0.1-0.1-0.10.4
Patch foraging water rate 0 sec0.91.54.22.0-1.5-1.5-1.91.6-1.6-1.2-1.7-1.71.71.70.80.80.70.7-0.60.8-0.50.5-0.1-0.20.4-0.3
Patch foraging water rate 12 sec1.72.67.51.7-0.4-0.5-2.61.1-0.70.3-2.7-2.72.72.70.00.00.10.11.11.8-1.61.6-1.5-1.51.2-1.4
Patch foraging water rate 18 sec1.62.14.61.9-1.8-1.8-2.12.0-1.7-0.9-2.1-2.12.12.11.21.21.21.2-0.10.7-0.40.4-0.2-0.3-0.1-1.1
Patch foraging water rate 24 sec0.81.22.40.70.30.3-1.4-0.10.30.7-1.5-1.51.51.5-0.5-0.5-0.5-0.51.01.6-1.51.5-1.4-1.41.3-0.8
Patch foraging water rate 6 sec0.81.23.41.1-0.5-0.4-1.70.5-0.20.2-1.9-1.91.91.9-0.1-0.1-0.0-0.00.71.3-1.21.2-1.0-1.10.9-0.8
Seeking ratio, delayed vs. immediate footshock1.21.43.9-1.50.50.50.6-1.92.01.60.60.6-0.6-0.6-1.8-1.8-1.6-1.61.40.6-0.80.8-1.1-1.00.9-0.7
Distance traveled before self-admin0.50.52.4-1.21.51.50.6-0.40.61.10.20.2-0.2-0.2-0.7-0.7-0.7-0.70.9-0.40.2-0.2-0.2-0.2-0.4-0.1
Distance traveled after self-admin0.80.92.2-0.30.20.3-0.8-0.10.00.9-1.5-1.51.51.5-0.7-0.7-0.7-0.70.91.1-1.11.1-1.1-1.10.1-0.9
Extensor digitorum longus weight0.10.20.9-0.40.20.10.50.20.1-0.10.40.4-0.4-0.40.30.30.30.3-0.0-1.00.9-0.90.60.6-0.90.2
Bone: elastic displacement1.71.94.0-1.81.51.50.4-1.81.92.0-0.0-0.00.00.0-1.8-1.8-1.8-1.81.80.8-1.01.0-1.4-1.41.0-1.1
Bone: elastic work3.44.38.5-2.31.91.90.1-2.42.72.8-0.6-0.60.60.6-2.9-2.9-2.8-2.82.81.5-1.81.8-2.2-2.21.9-1.6
Bone: endosteal estimation1.22.56.31.7-2.2-2.2-0.21.9-2.0-2.50.20.2-0.2-0.21.71.71.71.7-2.2-1.21.4-1.51.81.8-1.31.1
Bone: endosteal perimeter1.22.46.42.1-2.5-2.5-0.72.0-2.1-2.5-0.3-0.30.30.31.71.71.51.5-2.1-0.81.1-1.11.51.5-0.90.4
Epididymis fat weight0.40.92.5-1.00.60.61.10.3-0.0-0.10.90.9-0.9-0.90.80.80.70.7-0.2-1.61.5-1.51.01.0-1.50.9
Delta time in closed arm before/after self-admin2.52.55.6-0.91.00.91.80.5-0.5-0.61.71.7-1.7-1.71.21.21.21.2-1.1-2.42.2-2.21.91.9-2.22.1
Delta time in open arm before/after self-admin1.11.04.22.1-1.9-1.9-1.11.1-1.3-1.7-0.7-0.70.70.70.70.70.70.7-1.20.3-0.10.10.40.40.2-0.0
Diff in mean of infusions in LGA sessions1.01.14.3-1.00.30.32.1-0.80.5-0.21.31.3-1.3-1.30.00.00.00.0-0.9-1.51.3-1.31.21.2-0.81.1
Delay discount exponential model param0.40.41.00.5-1.0-1.0-1.00.7-0.60.0-0.8-0.80.80.80.40.40.20.20.30.6-0.50.5-0.5-0.50.2-0.7
Extinction: sum of active levers before priming0.00.00.1-0.3-0.2-0.20.2-0.30.30.2-0.1-0.10.10.10.10.10.10.10.2-0.00.0-0.0-0.1-0.1-0.3-0.3
Active lever presses in extinction session 62.32.34.90.8-0.4-0.3-1.9-0.10.10.5-2.1-2.12.12.1-0.9-0.9-0.9-0.90.92.1-2.02.0-1.7-1.72.2-1.4
Bone: final force1.01.64.2-0.40.30.31.50.1-0.6-1.01.51.5-1.5-1.50.90.90.90.9-1.7-1.41.4-1.41.61.6-1.22.1
Bone: final moment0.81.33.1-0.2-0.0-0.01.20.3-0.7-1.11.31.3-1.3-1.31.01.00.90.9-1.6-1.21.3-1.31.51.5-1.11.8
Food consumed during 24 hour testing period1.82.25.21.9-2.2-2.2-2.30.8-0.7-0.7-1.8-1.81.81.8-0.1-0.10.30.30.11.7-1.51.4-1.0-1.01.6-1.9
Glucose0.50.71.8-0.1-0.5-0.5-0.9-0.40.60.7-0.9-0.90.90.9-0.7-0.7-0.6-0.61.01.1-1.11.1-1.1-1.10.8-1.4
Heart weight0.40.52.21.5-0.9-0.9-1.10.7-0.8-0.7-0.9-0.90.90.90.20.20.20.2-0.30.7-0.50.5-0.2-0.20.6-0.4
Delay discount hyperbolic model param0.30.30.70.2-0.8-0.8-0.80.4-0.40.3-0.7-0.70.70.70.20.20.00.00.50.7-0.60.6-0.6-0.60.3-0.8
Intermittent access intake day 1-15 change1.61.64.11.1-0.1-0.1-1.70.30.20.6-2.0-2.02.02.0-0.7-0.7-0.8-0.81.11.4-1.31.3-1.3-1.31.0-1.4
Intermittent access intake escalation1.71.63.81.1-0.3-0.3-1.70.10.40.6-2.0-2.02.02.0-0.7-0.7-0.9-0.91.21.5-1.41.4-1.4-1.41.1-1.6
Intermittent access intake escalation 20.10.10.30.60.60.6-0.40.10.30.3-0.5-0.50.50.5-0.2-0.2-0.2-0.20.50.1-0.10.1-0.3-0.3-0.0-0.2
Intermitt. access day 1 inactive lever presses1.11.22.7-0.71.21.21.6-0.90.7-0.21.61.6-1.6-1.60.30.30.30.3-0.8-1.21.0-1.01.01.0-0.71.5
Intermitt. access day 15 inactive lever presses0.30.30.70.70.60.7-0.50.1-0.2-0.0-0.9-0.90.90.9-0.2-0.2-0.3-0.3-0.00.7-0.60.6-0.4-0.40.70.4
Intermitt. access escalation Index0.10.10.30.2-0.4-0.40.10.1-0.2-0.50.30.3-0.3-0.30.30.30.40.4-0.5-0.20.3-0.30.40.4-0.30.5
Intermittent access day 1 total infusions0.60.73.11.8-1.1-1.1-0.50.9-1.1-1.40.10.1-0.1-0.10.80.80.90.9-1.3-0.10.3-0.30.70.7-0.10.5
Intermittent access day 15 total infusions0.50.54.22.0-0.7-0.7-1.10.6-0.6-0.7-0.9-0.90.90.90.20.20.20.2-0.40.7-0.50.5-0.2-0.20.6-0.2
Intermittent access terminal intake (last 3 days)0.50.53.61.9-0.9-0.9-0.80.7-0.7-0.9-0.8-0.80.80.80.50.50.50.5-0.70.3-0.10.10.20.20.20.0
Intermittent access total infusions0.40.42.91.7-0.9-0.9-0.60.6-0.7-1.0-0.4-0.40.40.40.60.60.60.6-0.90.10.0-0.00.30.30.10.3
Intermittent access day 1 locomotion0.10.10.40.5-0.3-0.30.2-0.40.2-0.40.50.5-0.5-0.5-0.1-0.1-0.1-0.1-0.50.2-0.20.20.10.10.60.1
Intermittent access day 15 total locomotion1.01.12.71.2-0.7-0.6-1.4-0.10.20.1-1.3-1.31.31.3-0.6-0.6-0.7-0.70.51.4-1.31.3-1.0-1.01.7-1.3
Intermittent access total locomotion0.20.31.61.3-0.3-0.3-0.80.4-0.4-0.5-0.7-0.70.70.70.20.20.10.1-0.30.6-0.50.5-0.2-0.20.7-0.3
Intermittent access standard deviation0.20.20.60.10.60.6-0.4-0.10.50.5-0.8-0.80.80.8-0.3-0.3-0.4-0.40.60.3-0.30.3-0.4-0.40.2-0.4
Left kidney weight0.72.15.41.4-1.6-1.6-0.92.3-1.9-1.6-0.7-0.70.70.72.02.02.12.1-1.1-1.01.2-1.21.21.1-1.40.4
Right kidney weight0.61.64.00.9-1.0-1.0-0.31.8-1.6-1.4-0.2-0.20.20.21.81.82.02.0-1.1-1.11.3-1.31.31.2-1.60.9
Cocaine induced anxiety1.41.65.0-2.01.91.92.2-1.61.40.81.51.5-1.5-1.5-0.5-0.5-0.5-0.5-0.0-1.00.8-0.80.50.6-0.51.2
Post-drug Anxiety1.11.32.8-0.50.50.51.6-0.0-0.4-0.71.21.2-1.2-1.20.70.70.70.7-1.3-1.61.5-1.51.51.5-1.31.7
Baseline Anxiety1.11.23.31.8-1.8-1.8-0.81.5-1.6-1.70.10.1-0.1-0.11.11.11.11.1-1.3-0.20.5-0.50.80.8-0.50.3
Tail length5.416.429.03.1-5.1-5.1-0.25.0-5.2-5.40.60.6-0.6-0.65.15.15.25.2-4.9-3.43.9-4.04.44.4-4.01.7
Length with tail3.813.825.22.4-3.6-3.70.74.1-4.4-4.61.41.4-1.4-1.44.94.95.05.0-4.5-3.64.0-4.04.34.3-4.12.0
Length without tail0.10.30.7-0.20.40.40.8-0.20.0-0.00.80.8-0.8-0.80.40.40.50.5-0.5-0.50.5-0.50.50.5-0.70.6
Times rat made contact with spout0.30.40.8-0.4-0.6-0.60.7-0.00.1-0.40.70.7-0.7-0.70.30.30.70.7-0.5-0.90.9-0.90.80.8-0.80.1
Lifetime Intake0.50.63.81.9-1.1-1.1-1.00.9-0.9-1.0-0.7-0.70.70.70.60.60.60.6-0.70.4-0.20.20.20.10.2-0.0
Liver weight, left2.94.68.5-0.60.70.62.7-0.0-0.3-1.32.92.9-2.9-2.91.31.31.51.5-2.1-2.82.7-2.72.62.6-2.42.9
Liver weight, right4.77.914.3-0.50.30.33.10.8-1.2-1.93.33.3-3.3-3.32.12.12.52.5-2.8-3.73.6-3.63.53.5-3.73.8
Locomotor activity0.20.40.80.7-0.2-0.2-0.90.9-0.8-0.2-0.9-0.90.90.90.60.60.70.7-0.00.4-0.20.2-0.1-0.20.1-0.3
Locomotor testing distance1.01.63.91.8-1.5-1.5-1.62.0-1.7-1.2-1.5-1.51.51.51.41.41.41.4-0.60.30.0-0.00.20.2-0.2-0.6
Locomotor testing rearing1.21.84.21.4-1.5-1.5-0.41.8-1.8-1.6-0.2-0.20.20.22.12.11.81.8-1.4-1.01.2-1.21.31.3-1.50.3
Locomotion in novel chamber1.31.62.8-0.31.11.1-0.7-1.31.51.6-0.5-0.50.50.5-1.4-1.4-1.3-1.31.61.5-1.61.6-1.7-1.71.5-1.0
Locomotion in novel chamber post-restriction1.11.33.01.4-0.8-0.7-1.7-0.10.30.0-1.2-1.21.21.2-0.9-0.9-0.8-0.80.61.7-1.61.6-1.3-1.31.6-1.3
Fecal boli incidents, locomotor time 10.80.93.30.11.11.10.7-1.81.60.40.30.3-0.3-0.3-1.5-1.5-1.2-1.20.10.4-0.60.5-0.4-0.31.40.5
Change in fecal boli incidents, locomotor task0.30.31.1-0.90.60.60.20.6-0.60.10.40.4-0.4-0.40.70.70.50.50.1-0.50.5-0.40.30.3-1.01.0
Time >=10cm from walls, locomotor time 10.20.20.70.8-0.1-0.1-0.50.4-0.6-0.6-0.3-0.30.30.30.10.10.30.3-0.50.4-0.30.30.00.00.50.5
Bouts of movement, locomotor time 10.20.20.80.8-0.6-0.60.4-0.0-0.3-0.70.50.5-0.5-0.50.00.0-0.1-0.1-0.9-0.30.3-0.30.60.60.10.4
Total resting periods, locomotor time 10.10.10.50.4-0.1-0.00.3-0.60.4-0.00.20.2-0.2-0.2-0.6-0.6-0.7-0.7-0.20.2-0.20.2-0.0-0.00.50.1
Rest time, locomotor task time 10.10.10.70.1-0.1-0.10.3-0.3-0.2-0.20.30.3-0.3-0.3-0.2-0.2-0.2-0.2-0.40.1-0.10.10.10.10.00.8
Distance moved, locomotor task time 10.20.20.60.1-0.6-0.6-0.10.5-0.2-0.3-0.2-0.20.20.20.60.60.80.8-0.1-0.50.5-0.50.40.3-0.5-0.6
Vertical activity count, locomotor time 10.40.51.30.4-0.5-0.50.30.4-0.3-0.60.40.4-0.4-0.41.01.01.21.2-0.7-0.70.8-0.80.80.8-0.5-0.0
Time >=10cm from walls, locomotor time 21.92.05.01.5-0.6-0.6-0.41.9-2.2-2.0-0.4-0.40.40.42.02.02.02.0-2.0-0.70.9-1.01.41.4-1.21.7
Bouts of movement, locomotor time 22.73.05.60.5-1.0-1.01.41.1-1.5-1.91.51.5-1.5-1.51.81.81.51.5-2.4-2.12.2-2.22.42.4-1.91.7
Total resting periods, locomotor time 22.22.34.40.1-0.8-0.81.50.7-1.0-1.51.61.6-1.6-1.61.41.41.11.1-2.0-2.02.0-2.02.12.1-1.61.5
Rest time, locomotor task time 21.01.13.5-1.91.31.31.4-1.51.41.50.90.9-0.9-0.9-1.2-1.2-1.3-1.30.9-0.30.0-0.0-0.3-0.30.00.1
Distance moved, locomotor task time 21.61.95.62.4-1.5-1.5-1.41.9-1.8-1.7-1.4-1.41.41.41.61.61.71.7-1.20.00.3-0.30.60.6-0.50.0
Vertical activity count, locomotor time 21.31.52.91.2-1.1-1.10.31.1-1.3-1.60.00.0-0.0-0.01.71.71.71.7-1.7-1.11.2-1.21.41.4-1.00.9
Light reinforcement 11.12.07.9-2.82.32.31.0-1.61.92.30.30.3-0.3-0.3-1.4-1.4-1.5-1.51.9-0.1-0.30.3-0.9-0.9-0.0-0.3
Light reinforcement 22.83.77.4-1.30.50.5-1.4-0.91.52.2-2.0-2.02.02.0-1.9-1.9-2.1-2.12.71.9-2.02.0-2.4-2.41.9-2.7
Bone: marrow area1.12.45.71.5-2.0-2.0-0.01.7-1.9-2.40.30.3-0.3-0.31.61.61.61.6-2.2-1.31.5-1.51.81.8-1.31.2
Bone: maximum diameter1.42.55.82.3-2.4-2.4-0.82.1-2.2-2.3-0.4-0.40.40.41.91.91.81.8-2.0-0.60.9-1.01.41.3-0.90.4
Bone: maximum force0.50.82.1-0.0-0.2-0.20.90.2-0.6-1.01.01.0-1.0-1.00.60.60.70.7-1.4-0.91.0-1.01.21.2-0.81.4
Bone: maximum moment0.30.51.40.2-0.5-0.50.50.3-0.6-1.00.70.7-0.7-0.70.60.60.60.6-1.2-0.70.7-0.81.01.0-0.61.0
Mean time between licks in bursts5.57.715.53.3-2.7-2.7-0.53.8-3.9-3.90.20.2-0.2-0.23.73.73.53.5-3.5-2.12.5-2.53.02.9-2.41.7
Mean num. licks in bursts1.41.74.42.1-2.0-2.0-1.91.4-1.4-1.3-1.5-1.51.51.51.01.00.90.9-0.71.0-0.70.7-0.2-0.20.7-0.7
Cd content in liver0.30.30.7-0.50.10.10.8-0.50.60.10.80.8-0.8-0.8-0.3-0.3-0.5-0.5-0.0-0.70.6-0.60.40.4-0.40.0
Co content in liver2.42.86.11.9-2.1-2.10.01.8-2.1-2.50.70.7-0.7-0.72.02.01.91.9-2.4-1.21.4-1.51.91.9-1.31.0
Cu content in liver1.31.63.51.5-1.6-1.60.01.3-1.5-1.90.40.4-0.4-0.41.41.41.51.5-1.7-1.01.2-1.21.51.4-1.10.7
Fe content in liver0.40.51.3-0.1-0.5-0.50.7-0.1-0.1-0.61.11.1-1.1-1.10.40.40.50.5-0.9-0.70.6-0.70.80.8-0.40.4
K content in liver0.30.30.6-0.20.50.50.8-0.20.40.10.70.7-0.7-0.70.40.40.50.5-0.3-0.70.7-0.70.50.5-0.40.1
Mg content in liver0.00.10.20.4-0.1-0.1-0.30.10.0-0.1-0.3-0.30.30.30.20.20.30.30.00.1-0.10.1-0.0-0.10.2-0.5
Mn content in liver1.61.83.7-1.71.91.90.6-1.91.91.90.10.1-0.1-0.1-1.6-1.6-1.6-1.61.60.8-1.01.0-1.3-1.21.1-0.3
Na content in liver0.30.31.20.5-1.1-1.1-0.7-0.00.0-0.2-0.5-0.50.50.5-0.4-0.4-0.2-0.20.10.7-0.60.6-0.4-0.40.8-0.9
Rb content in liver0.40.52.61.1-1.6-1.6-0.40.5-0.6-1.10.00.0-0.0-0.00.40.40.60.6-0.9-0.00.1-0.20.50.50.1-0.3
Se content in liver1.82.25.4-2.32.12.11.9-2.32.21.61.51.5-1.5-1.5-1.6-1.6-1.5-1.50.9-0.3-0.00.1-0.4-0.30.30.6
Sr content in liver1.91.72.9-0.10.50.5-1.3-0.20.61.2-1.6-1.61.61.6-1.2-1.2-1.2-1.21.71.5-1.51.5-1.7-1.71.3-1.4
Zn content in liver1.61.85.22.1-1.4-1.4-2.31.4-1.0-0.8-2.0-2.02.02.00.30.30.20.20.11.2-0.90.9-0.7-0.71.0-1.3
Bone: minimum diameter1.93.65.71.3-1.8-1.80.61.9-2.0-2.31.01.0-1.0-1.02.32.32.42.4-2.4-2.02.2-2.22.42.3-2.11.2
Time in familiar zone, hab. session 10.20.20.60.0-0.6-0.6-0.30.7-0.7-0.4-0.2-0.20.20.20.60.60.60.6-0.2-0.20.3-0.30.20.2-0.4-0.3
Time in novel zone, hab. session 10.30.31.0-0.10.70.70.8-0.40.30.00.70.7-0.7-0.7-0.1-0.10.20.2-0.2-0.50.4-0.40.40.4-0.51.0
Total zone transitions, hab. session 10.70.92.20.4-0.5-0.5-1.0-0.30.30.5-1.1-1.11.11.1-0.9-0.9-0.9-0.90.81.3-1.21.2-1.1-1.11.1-1.5
Total locomotion distance, hab. session 11.52.15.3-0.30.40.31.31.0-1.0-0.91.21.2-1.2-1.21.61.61.81.8-1.2-2.02.0-2.01.81.7-2.31.6
Locomotion velocity, hab. session 11.01.53.6-0.20.40.41.10.8-0.8-0.71.01.0-1.0-1.01.31.31.41.4-1.1-1.71.7-1.71.51.5-1.91.3
Time in familiar zone, hab. session 21.51.54.21.3-1.0-1.0-0.61.8-2.1-1.7-0.3-0.30.30.31.71.71.81.8-1.5-0.50.7-0.71.01.0-1.01.2
Time in novel zone, hab. session 21.51.52.9-0.60.90.9-0.2-1.31.71.7-0.6-0.60.60.6-1.5-1.5-1.5-1.51.71.0-1.11.1-1.4-1.41.2-1.5
Total zone transitions, hab. session 21.62.14.71.7-1.9-1.8-2.21.0-1.0-0.3-2.1-2.12.12.10.10.10.20.20.31.6-1.41.4-1.0-1.11.1-1.9
Total locomotion distance, hab. session 22.22.97.70.8-0.5-0.50.32.1-2.1-1.50.30.3-0.3-0.32.52.52.82.8-1.6-1.71.9-1.91.81.8-2.31.2
Locomotion velocity, hab. session 22.43.27.70.7-0.6-0.60.52.1-2.1-1.50.50.5-0.5-0.52.62.62.82.8-1.7-1.92.1-2.12.02.0-2.51.2
Novel to familiar place preference ratio1.41.43.20.5-0.3-0.31.00.5-1.0-1.21.41.4-1.4-1.41.31.31.11.1-1.8-1.11.2-1.21.51.5-1.11.5
Novelty place preference1.41.43.10.6-0.3-0.30.90.6-1.1-1.21.31.3-1.3-1.31.31.31.11.1-1.8-1.11.2-1.21.51.5-1.11.4
Time in novel zone, NPP test1.41.53.50.8-0.4-0.40.80.8-1.3-1.41.21.2-1.2-1.21.41.41.31.3-1.9-1.11.2-1.21.51.5-1.11.5
Total zone transitions, NPP test1.21.84.60.7-0.3-0.2-1.4-0.40.71.0-1.6-1.61.61.6-1.1-1.1-1.0-1.01.41.6-1.61.6-1.6-1.61.5-2.1
Total locomotion distance, NPP test0.40.51.6-0.10.90.90.40.7-0.30.10.10.1-0.1-0.10.90.90.90.9-0.0-1.11.1-1.00.70.6-1.30.3
Locomotion velocity, NPP test0.30.41.4-0.41.21.10.50.4-0.00.40.10.1-0.1-0.10.70.70.70.70.3-1.01.0-0.90.50.5-1.20.2
Intraocular pressure1.41.93.8-0.2-0.1-0.0-0.9-1.31.41.0-1.0-1.01.01.0-1.9-1.9-1.9-1.91.51.7-1.71.7-1.7-1.71.7-1.0
Delta distance traveled before/after self-admin1.11.23.71.8-1.9-1.9-1.01.2-1.6-1.5-0.9-0.90.90.91.11.11.11.1-1.30.5-0.30.20.30.3-0.30.2
Delta ambulatory time before/after self-admin0.80.92.61.5-1.6-1.6-1.20.8-1.1-1.0-1.1-1.11.11.10.60.60.60.6-0.71.0-0.70.7-0.2-0.20.2-0.1
Parametrial fat weight0.20.51.6-0.80.80.80.3-0.61.11.1-0.1-0.10.10.1-1.1-1.1-0.8-0.81.3-0.30.1-0.1-0.4-0.4-0.1-0.6
Pavlov. Cond. lever latency0.40.62.4-1.61.41.40.5-0.70.81.20.00.0-0.0-0.0-0.7-0.7-0.6-0.61.00.0-0.20.2-0.5-0.5-0.20.2
Pavlov. Cond. magazine entry latency1.41.94.82.2-2.1-2.2-1.72.0-1.9-1.7-1.2-1.21.21.21.51.51.31.3-1.00.30.0-0.10.40.40.0-0.6
Pavlov. Cond. change in total contacts0.80.92.71.5-1.5-1.5-0.41.0-1.2-1.60.20.2-0.2-0.20.90.90.80.8-1.4-0.30.5-0.50.90.9-0.20.4
Pavlov. Cond. index score1.21.55.32.3-2.3-2.3-1.31.5-1.5-1.7-0.8-0.80.80.81.11.10.90.9-1.10.20.1-0.10.50.50.2-0.7
Pavlov. Cond. latency score1.11.44.92.2-2.2-2.2-1.21.4-1.4-1.7-0.6-0.60.60.61.21.20.90.9-1.20.10.1-0.20.60.60.2-0.5
Pavlov. Cond. lever contacts0.40.52.31.5-1.4-1.4-0.60.8-0.8-1.2-0.1-0.10.10.10.70.70.50.5-0.8-0.10.2-0.20.50.50.1-0.3
Pavlov. Cond. magazine entry number1.31.75.6-2.42.42.41.7-1.51.51.51.21.2-1.2-1.2-1.0-1.0-0.8-0.80.9-0.60.3-0.3-0.1-0.1-0.51.0
Pavlov. Cond. intertrial magazine entries0.30.41.3-1.10.80.81.1-1.00.80.60.80.8-0.8-0.8-0.6-0.6-0.2-0.20.1-0.30.2-0.20.10.1-0.30.5
Pavlov. Cond. lever-magazine prob. diff.0.91.24.52.0-2.1-2.1-1.31.3-1.3-1.5-0.7-0.70.70.70.90.90.60.6-0.90.3-0.00.00.30.30.3-0.7
Pavlov. Cond. response bias0.60.72.51.6-1.5-1.5-0.91.1-1.0-1.1-0.5-0.50.50.50.90.90.70.7-0.70.00.1-0.10.40.40.1-0.4
Pavlov. Cond. lever latency8.211.032.5-5.75.05.04.7-4.64.23.43.83.8-3.8-3.8-2.9-2.9-2.7-2.71.7-1.50.7-0.7-0.2-0.1-0.51.8
Pavlov. Cond. magazine entry latency3.13.69.81.9-1.8-1.8-3.11.6-1.1-0.2-3.0-3.03.03.00.40.40.30.30.92.0-1.71.7-1.5-1.51.4-2.4
Pavlov. Cond. change in total contacts7.410.226.75.2-4.9-4.9-4.74.1-3.8-2.8-3.9-3.93.93.92.52.52.22.2-1.21.9-1.21.1-0.3-0.40.9-2.5
Pavlov. Cond. index score6.58.321.44.6-4.3-4.3-4.33.8-3.4-2.5-3.6-3.63.63.62.32.32.12.1-1.01.7-1.11.0-0.3-0.40.9-2.2
Pavlov. Cond. latency score6.07.518.54.3-3.9-3.9-4.23.4-3.0-2.1-3.6-3.63.63.61.91.91.81.8-0.61.8-1.31.2-0.6-0.71.0-2.3
Pavlov. Cond. lever contacts8.411.534.45.9-5.4-5.4-4.74.5-4.3-3.6-3.7-3.73.73.73.03.02.82.8-1.91.5-0.70.70.20.10.6-2.0
Pavlov. Cond. magazine entry number4.35.214.1-2.92.82.83.8-2.31.80.93.43.4-3.4-3.4-0.8-0.8-0.6-0.6-0.4-2.21.8-1.81.31.4-1.62.6
Pavlov. Cond. intertrial magazine entries1.52.03.10.6-1.2-1.20.90.9-1.0-1.61.31.3-1.3-1.31.61.61.51.5-1.7-1.61.7-1.71.81.8-1.61.0
Pavlov. Cond. lever-magazine prob. diff.6.27.919.74.4-4.2-4.2-4.23.8-3.4-2.5-3.5-3.53.53.52.32.32.12.1-1.01.5-0.90.9-0.2-0.30.7-2.1
Pavlov. Cond. response bias8.611.732.15.7-5.3-5.3-5.04.5-4.1-3.3-4.1-4.14.14.12.82.82.52.5-1.51.9-1.11.1-0.2-0.30.9-2.4
Time in closed arm before self-admin1.82.14.81.5-0.7-0.6-2.20.5-0.60.2-2.0-2.02.02.0-0.3-0.3-0.3-0.30.72.2-2.02.0-1.6-1.61.8-1.4
Time in closed arm after self-admin0.50.52.4-0.81.51.60.7-0.80.60.80.60.6-0.6-0.6-0.6-0.6-0.6-0.60.30.1-0.20.2-0.2-0.20.30.8
Time in open arm before self-admin2.22.48.6-2.92.32.22.2-1.92.21.71.61.6-1.6-1.6-1.1-1.1-1.1-1.11.1-1.10.7-0.70.00.1-0.70.6
Time in open arm after self-admin0.30.31.00.1-0.4-0.50.40.4-0.3-0.70.20.2-0.2-0.20.50.50.50.5-0.6-0.90.9-0.90.80.8-1.00.7
Bone: periosteal estimation1.02.04.71.7-1.9-1.9-0.21.7-1.7-2.20.10.1-0.1-0.11.61.61.61.6-2.0-1.11.3-1.31.61.6-1.10.9
Bone: periosteal perimeter0.91.53.41.8-1.8-1.8-0.71.7-1.7-1.8-0.4-0.40.40.41.51.51.31.3-1.5-0.60.8-0.81.11.1-0.70.2
Bone: post-yield work0.10.20.80.5-0.1-0.1-0.30.6-0.7-0.4-0.3-0.30.30.30.50.50.50.5-0.4-0.00.1-0.10.20.2-0.40.9
Progressive ratio test 1 active lever presses0.00.00.00.1-0.00.0-0.10.0-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.1-0.10.1-0.10.1-0.0-0.00.1-0.0
Progressive ratio test 1 breakpoint0.00.00.10.2-0.2-0.20.00.1-0.2-0.3-0.1-0.10.10.10.00.00.00.0-0.2-0.10.1-0.10.10.2-0.00.1
Progressive ratio test 1 inactive lever presses0.10.10.90.90.20.2-0.1-0.0-0.0-0.50.30.3-0.3-0.30.20.20.20.2-0.50.1-0.00.00.20.20.20.4
Progressive ratio test 2 active lever presses0.40.52.51.6-1.1-1.1-0.10.4-0.6-1.10.30.3-0.3-0.30.60.60.60.6-1.1-0.20.3-0.30.60.6-0.10.2
Progressive ratio test 2 breakpoint0.50.62.61.6-1.1-1.1-0.10.6-0.7-1.20.30.3-0.3-0.30.70.70.70.7-1.2-0.30.4-0.40.70.7-0.20.4
Progressive ratio test 2 inactive lever presses0.10.21.21.1-0.2-0.2-0.4-0.1-0.1-0.4-0.4-0.40.40.40.10.10.10.1-0.40.6-0.50.5-0.1-0.10.60.1
Incentive Sensitization - Responses1.01.03.71.9-1.3-1.3-0.31.0-1.1-1.60.20.2-0.2-0.21.21.21.31.3-1.5-0.40.6-0.61.00.9-0.40.5
Incentive Sensitization - Breakpoint0.70.73.31.8-1.2-1.2-0.50.8-0.8-1.30.00.0-0.0-0.00.90.91.01.0-1.1-0.10.3-0.30.70.6-0.20.2
Sum of active levers in priming session hrs 5-60.20.20.7-0.1-0.3-0.3-0.50.3-0.20.3-0.8-0.80.80.80.20.20.20.20.30.4-0.40.4-0.4-0.4-0.2-0.9
Progressive ratio0.60.71.2-0.4-0.3-0.3-0.7-0.50.70.7-0.8-0.80.80.8-1.0-1.0-1.0-1.01.01.0-1.01.0-1.0-1.01.1-1.1
Food seeking constrained by brief footshock1.11.43.31.7-1.1-1.1-0.71.8-1.8-1.6-0.6-0.60.60.61.61.61.61.6-1.2-0.60.8-0.81.01.0-0.90.3
Seeking ratio, punishment vs. effort1.72.14.51.5-0.5-0.60.01.8-1.8-1.80.30.3-0.3-0.32.12.12.12.1-1.7-1.41.5-1.51.61.6-1.61.1
Retroperitoneal fat weight1.96.216.3-1.50.90.82.80.9-0.5-0.72.52.5-2.5-2.52.22.22.32.3-1.3-4.03.8-3.83.02.9-3.92.0
Reaction time number correct0.30.51.2-0.10.50.5-0.5-0.50.40.8-0.5-0.50.50.5-0.5-0.5-0.6-0.60.61.1-1.11.1-1.0-1.01.1-0.6
Reaction time mean minus median0.40.51.61.3-0.3-0.4-0.20.9-0.9-1.0-0.1-0.10.10.10.90.91.01.0-0.9-0.50.6-0.60.70.7-0.50.5
Reaction time mean minus median AUC0.30.31.71.3-0.4-0.4-0.40.7-0.7-0.8-0.2-0.20.20.20.80.80.90.9-0.7-0.00.1-0.10.40.3-0.10.2
Reaction time num false alarms1.72.45.7-1.51.81.82.4-0.90.80.32.32.3-2.3-2.30.20.20.30.3-0.5-1.81.6-1.61.21.3-1.51.7
Reaction time num false alarms AUC1.31.74.4-1.21.71.72.1-1.11.00.52.12.1-2.1-2.1-0.2-0.2-0.1-0.1-0.3-1.31.1-1.10.80.9-0.91.3
Reaction time trials correct on left0.30.51.2-0.10.50.5-0.5-0.50.40.8-0.5-0.50.50.5-0.5-0.5-0.6-0.60.61.1-1.11.1-1.0-1.01.1-0.6
Reaction time trials on left0.40.51.3-0.10.50.5-0.5-0.60.50.8-0.5-0.50.50.5-0.5-0.5-0.6-0.60.71.1-1.11.1-1.0-1.01.1-0.6
Reaction time mean1.72.34.8-0.81.31.22.1-0.40.2-0.32.22.2-2.2-2.20.90.91.11.1-1.1-1.91.7-1.71.51.6-1.61.9
Reaction time mean AUC1.52.04.9-0.91.21.22.1-0.70.5-0.12.22.2-2.2-2.20.70.70.80.8-0.9-1.61.5-1.51.31.4-1.41.7
Median of all reaction times1.92.56.0-1.41.61.62.4-0.90.60.12.42.4-2.4-2.40.70.70.80.8-0.8-1.81.6-1.61.41.4-1.51.9
Reaction time omissions0.20.30.7-0.60.60.50.8-0.50.70.40.80.8-0.8-0.80.30.30.20.20.2-0.60.5-0.50.20.2-0.40.1
Reaction time false alarm rate1.31.94.3-1.21.61.62.1-0.80.80.32.02.0-2.0-2.00.00.00.10.1-0.4-1.71.5-1.51.11.2-1.31.5
Reaction time premature initiation rate1.72.25.01.6-1.6-1.6-0.52.2-2.0-2.0-0.3-0.30.30.31.91.91.91.9-1.6-1.31.5-1.51.61.5-1.30.6
Reaction time premature initiations0.60.92.21.4-1.1-1.1-0.81.5-1.4-1.2-0.5-0.50.50.51.21.21.11.1-0.9-0.40.6-0.60.70.6-0.3-0.0
Std. dev. reaction times1.52.23.60.8-0.3-0.31.20.8-0.9-1.51.51.5-1.5-1.51.51.51.61.6-1.8-1.81.9-1.91.91.9-1.61.5
Reaction time trials completed0.40.51.3-0.10.50.5-0.5-0.60.50.8-0.5-0.50.50.5-0.5-0.5-0.6-0.60.71.1-1.11.1-1.0-1.01.1-0.6
Reaction time trials AUC0.20.30.7-0.00.50.5-0.4-0.30.20.6-0.4-0.40.40.4-0.2-0.2-0.3-0.30.50.8-0.80.8-0.7-0.70.8-0.3
Run reversals in cocaine runway, females1.81.73.60.5-0.8-0.90.21.7-1.3-1.10.60.6-0.6-0.61.81.81.71.7-0.8-1.71.8-1.81.51.4-1.90.2
Run reversals in cocaine runway, males0.30.31.0-0.8-0.1-0.10.5-1.00.90.30.40.4-0.4-0.4-0.7-0.7-0.7-0.70.20.1-0.20.2-0.2-0.20.3-0.1
Latency to leave start box in cocaine runway0.40.41.5-1.20.50.61.2-0.60.70.40.30.3-0.3-0.3-0.5-0.5-0.7-0.70.2-1.00.8-0.80.50.5-0.50.7
Latency to leave start box in cocaine runway, F0.70.72.4-0.70.40.41.4-0.10.1-0.30.60.6-0.6-0.60.30.30.10.1-0.6-1.51.4-1.41.21.2-1.11.2
Latency to leave start box in cocaine runway, M0.80.82.0-0.90.60.60.2-1.21.31.1-0.2-0.20.20.2-1.4-1.4-1.4-1.41.00.6-0.70.7-0.9-0.90.8-0.5
Std. dev. time between licks in bursts2.93.55.71.6-1.1-1.10.42.1-2.2-2.40.70.7-0.7-0.72.32.32.22.2-2.4-2.02.2-2.22.42.3-2.21.7
Total sessions with >9 infusions2.12.35.92.1-1.7-1.7-2.41.1-0.9-0.5-2.3-2.32.32.3-0.1-0.1-0.1-0.10.41.7-1.51.5-1.1-1.21.4-1.5
Short access day 1 total inactive lever presses0.30.31.00.30.30.31.0-0.80.5-0.30.70.7-0.7-0.7-0.2-0.2-0.1-0.1-0.8-0.40.3-0.40.50.60.10.9
Short access day 10 total inactive lever presses0.50.52.5-0.51.61.60.8-1.01.00.60.60.6-0.6-0.6-0.5-0.5-0.5-0.50.2-0.10.0-0.0-0.1-0.00.20.6
Short access day 1 total infusions1.11.14.72.2-1.7-1.7-1.11.3-1.3-1.4-0.8-0.80.80.81.01.01.01.0-1.10.20.0-0.00.40.40.1-0.1
Short access day 10 total infusions0.70.84.02.0-1.5-1.4-0.91.1-1.1-1.4-0.5-0.50.50.50.90.90.80.8-1.00.10.1-0.10.50.4-0.0-0.1
Short access total infusions0.70.83.01.7-1.4-1.4-1.01.1-1.1-1.1-0.9-0.90.90.90.70.70.70.7-0.70.3-0.10.00.20.20.0-0.1
Short access day 1 locomotion1.61.84.10.7-1.0-1.0-1.6-0.50.60.5-1.2-1.21.21.2-1.2-1.2-1.2-1.21.01.9-1.91.9-1.6-1.62.0-1.7
Short access day 10 total locomotion0.10.20.50.60.10.1-0.50.20.10.0-0.7-0.70.70.70.30.30.10.10.20.2-0.20.2-0.2-0.20.4-0.6
Short access total locomotion0.20.20.50.3-0.3-0.3-0.5-0.20.30.1-0.4-0.40.40.4-0.3-0.3-0.3-0.30.30.7-0.60.6-0.5-0.50.7-0.7
One hour access (0.3 mA shock)0.50.63.82.0-0.3-0.3-1.20.9-0.6-0.7-1.0-1.01.01.00.60.60.60.6-0.30.5-0.30.3-0.1-0.10.2-0.2
Compulsive drug intake0.80.81.7-1.10.70.70.1-1.31.31.10.10.1-0.1-0.1-1.3-1.3-1.2-1.21.10.8-0.90.9-1.0-1.01.0-0.2
One hour access (shock baseline)0.91.04.62.1-0.8-0.8-0.81.4-1.3-1.3-0.6-0.60.60.61.31.31.31.3-1.1-0.20.4-0.40.70.6-0.40.2
Social response proportion0.30.40.9-0.30.90.90.70.10.10.20.70.7-0.7-0.70.40.40.30.3-0.1-0.90.9-0.90.60.6-0.70.2
Social responses1.41.83.70.10.40.31.30.8-0.7-0.81.51.5-1.5-1.51.41.41.31.3-1.3-1.91.9-1.91.71.7-1.81.0
Social time0.91.24.0-1.52.02.01.3-1.41.41.50.90.9-0.9-0.9-1.0-1.0-1.4-1.40.9-0.1-0.10.1-0.4-0.40.20.0
Soleus weight0.82.35.60.20.30.21.40.9-0.7-1.21.51.5-1.5-1.51.31.31.21.2-1.4-2.42.3-2.32.12.1-2.11.6
Bone: stiffness2.23.56.5-0.30.10.12.10.4-0.9-1.52.32.3-2.3-2.31.31.31.41.4-2.3-2.32.2-2.22.42.4-2.12.6
Tibialis anterior weight0.31.11.80.3-0.3-0.30.41.1-1.1-1.10.60.6-0.6-0.61.21.21.41.4-1.3-1.21.3-1.31.31.3-1.31.2
Time to tail flick, vehicle, before self-admin0.20.21.00.2-1.0-1.0-0.40.3-0.4-0.2-0.5-0.50.50.50.20.20.20.2-0.10.3-0.20.2-0.1-0.10.1-0.4
Time to tail flick, vehicle, after self-admin1.21.33.61.8-1.9-1.9-1.50.4-0.6-0.8-1.6-1.61.61.6-0.2-0.2-0.2-0.2-0.31.3-1.11.1-0.6-0.61.0-0.9
Time to tail flick, test, before self-admin0.90.93.41.4-1.8-1.8-0.61.2-1.3-1.4-0.3-0.30.30.30.90.90.90.9-1.0-0.30.4-0.50.70.7-0.50.0
Time to tail flick, test, after self-admin2.52.64.61.3-1.8-1.80.21.8-2.0-2.20.30.3-0.3-0.31.91.91.91.9-2.1-1.51.7-1.71.91.9-2.01.0
Delta time to tail flick, vehicle, before/after SA0.60.61.41.0-0.6-0.6-1.0-0.30.3-0.2-0.9-0.90.90.9-0.7-0.7-0.7-0.70.21.1-1.01.0-0.7-0.71.2-0.7
Delta time to tail flick, test, before/after SA0.10.10.7-0.40.60.60.4-0.00.10.20.20.2-0.2-0.20.10.10.10.10.0-0.50.4-0.40.30.3-0.90.3
Tibia length0.30.82.41.2-1.5-1.5-1.20.3-0.6-0.9-0.7-0.70.70.70.30.30.50.5-0.71.2-1.01.0-0.3-0.31.3-0.6
Ambulatory time before self-admin0.60.72.7-1.31.61.60.7-0.70.81.20.40.4-0.4-0.4-0.9-0.9-0.9-0.90.9-0.2-0.00.0-0.4-0.4-0.20.0
Ambulatory time after self-admin0.70.82.3-0.10.10.2-0.8-0.0-0.20.6-1.5-1.51.51.5-0.5-0.5-0.5-0.50.61.2-1.11.1-1.0-1.00.4-0.4
Bone: tissue strength2.62.54.2-0.90.80.8-0.9-1.31.51.9-1.1-1.11.11.1-1.9-1.9-1.8-1.82.01.8-1.91.9-2.0-2.01.8-1.6
Total heroin consumption0.50.61.50.7-0.9-0.9-1.10.9-0.8-0.1-1.2-1.21.21.20.70.70.70.70.10.6-0.50.5-0.4-0.40.1-1.0
Bone: trabecular number0.91.53.1-1.30.91.00.3-1.71.71.50.10.1-0.1-0.1-1.8-1.8-1.7-1.71.40.9-1.01.0-1.2-1.21.2-0.8
Bone: trabecular spacing0.70.92.30.8-0.5-0.5-1.50.4-0.10.2-1.5-1.51.51.5-0.1-0.1-0.2-0.20.81.1-1.01.0-1.0-1.01.1-1.4
Bone: trabecular thickness1.51.82.9-0.2-0.2-0.21.40.4-0.9-1.11.61.6-1.6-1.61.21.21.11.1-1.7-1.51.5-1.51.61.7-1.61.7
Bone: trabecular tissue density4.86.711.3-0.20.30.32.90.7-1.1-1.83.23.2-3.2-3.22.22.22.22.2-2.8-3.43.3-3.33.23.3-3.23.0
Water consumed over 24 hours0.30.31.2-1.10.30.30.6-1.11.00.70.50.5-0.5-0.5-1.0-1.0-0.1-0.10.50.2-0.30.3-0.4-0.40.2-0.3
Number of responses in last shaping day0.80.81.70.5-0.9-0.90.70.3-0.5-1.11.11.1-1.1-1.10.70.70.70.7-1.3-0.90.9-0.91.11.2-0.60.9