Hub : Traits

Distance traveled before self-admin

Distance traveled in cm at the first time point of open field before self admin

Tags: Behavior · Heroin · Open field test

Project: u01_peter_kalivas

4 loci · 4 genes with independent associations · 4 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr5	118282290	119677504	1	1	7.70e-12	3.18e-01	1.00e+00	Atg4c
2	chr9	83390749	84777604	1	1	0.00e+00	7.27e-01	1.00e+00	Retreg2
3	chr10	13551895	14951178	1	1	1.89e-07	6.93e-04	1.38e-01	Rnf151
4	chr17	61510864	62906219	1	1	4.11e-32	3.81e-02	9.76e-11	Ccny

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	1920.21	2	1	25	0	1.00e+00	Ccny Retreg2
BMI without tail	72013.97	2	2	50	0	1.00e+00	Ccny Retreg2
Body weight	3.91	1	0	0	0	1.00e+00	Retreg2
Epididymis fat weight	54253.01	2	2	50	0	1.00e+00	Ccny Retreg2
Glucose	795.14	3	1	25	0	1.00e+00	Atg4c Retreg2 Rnf151
Heart weight	6763.89	2	2	50	0	1.00e+00	Ccny Retreg2
Left kidney weight	70630.9	2	1	25	0	1.00e+00	Ccny Retreg2
Right kidney weight	58431.64	2	2	50	0	1.00e+00	Ccny Retreg2
Tail length	46066.56	2	2	50	0	1.00e+00	Ccny Retreg2
Length with tail	6138.87	1	1	25	0	1.00e+00	Retreg2
Length without tail	64667	2	2	50	0	1.00e+00	Ccny Retreg2
Liver weight, left	7265.45	2	2	50	0	1.00e+00	Ccny Retreg2
Liver weight, right	129.69	2	1	25	0	1.00e+00	Ccny Retreg2
Parametrial fat weight	311.74	2	1	25	0	1.00e+00	Ccny Retreg2
Retroperitoneal fat weight	8031.54	2	2	50	0	1.00e+00	Atg4c Retreg2
Intraocular pressure	40071.91	1	1	25	0	1.00e+00	Retreg2
Extensor digitorum longus weight	4682.69	1	1	25	0	1.00e+00	Retreg2
Soleus weight	59.13	2	1	25	0	1.00e+00	Ccny Retreg2
Tibialis anterior weight	4881.94	1	1	25	0	1.00e+00	Retreg2
Tibia length	3259.43	1	1	25	0	1.00e+00	Retreg2
Number of licking bursts	78561.42	2	1	25	0	1.00e+00	Ccny Retreg2
Food consumed during 24 hour testing period	26554.05	4	1	25	-1	4.24e-04	Atg4c Ccny Retreg2 Rnf151
Times rat made contact with spout	155.92	2	1	25	0	1.00e+00	Retreg2 Rnf151
Mean time between licks in bursts	99755.05	2	1	25	0	1.00e+00	Ccny Retreg2
Mean num. licks in bursts	71302.54	2	1	25	0	1.00e+00	Ccny Retreg2
Std. dev. time between licks in bursts	94042.02	1	1	25	0	1.00e+00	Retreg2
Water consumed over 24 hours	51711.02	2	1	25	0	1.00e+00	Ccny Retreg2
Patch foraging indifference point 0 sec	57503.47	2	1	25	0	1.00e+00	Atg4c Retreg2
Patch foraging indifference point AUC	66593.63	2	2	50	0	1.00e+00	Ccny Retreg2
Indifference point function ln k	71038.09	2	2	50	0	1.00e+00	Ccny Retreg2
Indifference point function log k	71038.09	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 0 sec	60133.94	2	1	25	0	1.00e+00	Atg4c Retreg2
Patch foraging total patch changes 12 sec	3673.81	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Patch foraging total patch changes 18 sec	39259.62	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Patch foraging total patch changes 24 sec	83555.1	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 6 sec	10903.88	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Patch foraging time to switch 0 sec	156618.53	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 0 sec	148807.58	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 12 sec	80953.12	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 18 sec	51643.12	2	1	25	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 24 sec	2357.13	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 6 sec	1354.04	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Locomotor activity	35.04	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotor testing distance	44778.43	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotor testing rearing	152414.81	1	1	25	0	1.00e+00	Retreg2
Light reinforcement 1	51781.05	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Light reinforcement 2	54020.7	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time number correct	76747.74	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time mean minus median	102906.71	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time mean minus median AUC	208396.98	1	1	25	0	1.00e+00	Retreg2
Reaction time num false alarms	28557.11	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time num false alarms AUC	53265.52	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time trials correct on left	76747.74	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time trials on left	75015.72	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time mean	31463.02	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Reaction time mean AUC	37783.79	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Median of all reaction times	15711.14	2	1	25	0	1.00e+00	Atg4c Retreg2
Reaction time omissions	34267.91	1	1	25	0	1.00e+00	Retreg2
Reaction time false alarm rate	447.96	2	1	25	0	1.00e+00	Atg4c Retreg2
Reaction time premature initiation rate	18442.81	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time premature initiations	69362.16	2	1	25	0	1.00e+00	Ccny Retreg2
Std. dev. reaction times	49830.5	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Reaction time trials completed	75015.72	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time trials AUC	75869.15	2	2	50	0	1.00e+00	Ccny Retreg2
Social response proportion	17659.31	2	1	25	0	1.00e+00	Atg4c Retreg2
Social responses	2856.43	2	2	50	0	1.00e+00	Ccny Retreg2
Social time	22121.54	2	1	25	0	1.00e+00	Ccny Retreg2
Conditioned locomotion	3044.63	2	1	25	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. corrected	21944.93	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Cocaine response after cond. not corrected	21419.84	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Cocaine response before conditioning	1409.02	2	1	25	0	1.00e+00	Ccny Retreg2
Saline control response	12962.78	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	53410.48	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	91582.24	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	9691.24	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	21056.03	2	1	25	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever presses	7938.93	2	1	25	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever reinforcers received	2000.77	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	10912.53	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	16477.7	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Pavlov. Cond. change in total contacts	114781.94	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. index score	23998.4	2	1	25	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. latency score	29242.48	2	1	25	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever contacts	22069.78	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	8389.95	2	1	25	0	1.00e+00	Atg4c Retreg2
Pavlov. Cond. intertrial magazine entries	104933.78	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	22438.69	2	1	25	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. response bias	2587.18	2	1	25	0	1.00e+00	Ccny Retreg2
Conditioned reinforcement - actives	95753.16	2	2	50	0	1.00e+00	Ccny Retreg2
Conditioned reinforcement - inactives	51687.18	3	3	75	0	1.00e+00	Atg4c Ccny Retreg2
Conditioned locomotion	20734.34	2	2	50	0	1.00e+00	Ccny Retreg2
Intermittent access intake day 1-15 change	70205.09	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Intermittent access intake escalation	104772.85	2	1	25	0	1.00e+00	Atg4c Retreg2
Intermittent access intake escalation 2	54050.4	2	2	50	0	1.00e+00	Ccny Retreg2
Intermitt. access day 1 inactive lever presses	118272.07	2	1	25	0	1.00e+00	Ccny Retreg2
Intermitt. access day 15 inactive lever presses	208241.66	1	1	25	0	1.00e+00	Retreg2
Intermitt. access escalation Index	92502.05	2	1	25	0	1.00e+00	Ccny Retreg2
Intermittent access day 1 total infusions	51845.26	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Intermittent access day 15 total infusions	43832.52	3	1	25	0	1.00e+00	Ccny Retreg2 Rnf151
Intermittent access terminal intake (last 3 days)	27737.89	3	1	25	0	1.00e+00	Ccny Retreg2 Rnf151
Intermittent access total infusions	345.81	2	1	25	0	1.00e+00	Ccny Retreg2
Intermittent access day 1 locomotion	52247.41	2	2	50	0	1.00e+00	Ccny Retreg2
Intermittent access day 15 total locomotion	59299.27	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Intermittent access total locomotion	711.59	1	1	25	0	1.00e+00	Retreg2
Intermittent access standard deviation	100979.14	2	2	50	0	1.00e+00	Ccny Retreg2
Cocaine induced anxiety	80149.68	2	2	50	0	1.00e+00	Ccny Retreg2
Post-drug Anxiety	20460.83	1	1	25	0	1.00e+00	Retreg2
Baseline Anxiety	51769.43	2	2	50	0	1.00e+00	Ccny Retreg2
Lifetime Intake	3437.35	2	2	50	0	1.00e+00	Ccny Retreg2
Incentive Sensitization - Responses	54535.26	3	3	75	0	1.00e+00	Atg4c Ccny Retreg2
Incentive Sensitization - Breakpoint	47607.9	3	3	75	0	1.00e+00	Atg4c Ccny Retreg2
Progressive ratio test 1 active lever presses	49966.26	2	2	50	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 breakpoint	48151.76	2	2	50	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 inactive lever presses	50373.32	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Progressive ratio test 2 active lever presses	19091.13	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Progressive ratio test 2 breakpoint	11683.33	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Progressive ratio test 2 inactive lever presses	54708.05	3	2	50	0	1.00e+00	Ccny Retreg2 Rnf151
Total sessions with >9 infusions	2684.86	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Short access day 1 total inactive lever presses	57203.57	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 10 total inactive lever presses	108624.06	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 1 total infusions	55866.13	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 10 total infusions	25435.06	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Short access total infusions	17026.24	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 1 locomotion	42054.78	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 10 total locomotion	60536.75	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Short access total locomotion	34135.46	2	1	25	0	1.00e+00	Ccny Retreg2
Compulsive drug intake	32724.39	2	1	25	0	1.00e+00	Ccny Retreg2
One hour access (0.3 mA shock)	4858.65	2	2	50	0	1.00e+00	Ccny Retreg2
One hour access (shock baseline)	70135.77	2	1	25	0	1.00e+00	Ccny Retreg2
Number of responses in last shaping day	25706.97	2	2	50	0	1.00e+00	Ccny Retreg2
Context. condit. distance diff. score	488.1	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 1	7310.5	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion distance, session 1	2213.01	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 2	4683.52	2	1	25	0	1.00e+00	Atg4c Retreg2
Locomotion distance, session 2	1206.44	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 3	2332.53	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	5866.4	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	12131.92	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 7	1310.17	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 7	3744.54	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 7	10466.92	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	8847.36	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 8	950.4	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion distance, session 8	673.32	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization distance	15309.16	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	8496.38	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	1382.49	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Condit. Reinf. active-inactive response ratio	555.67	2	1	25	0	1.00e+00	Atg4c Retreg2
Condit. Reinf. active responses	3898.02	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Condit. Reinf. inactive responses	19375.3	1	1	25	0	1.00e+00	Retreg2
Incentive salience index mean	4935.93	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Condit. Reinf. lever presses	10719.1	2	1	25	0	1.00e+00	Ccny Retreg2
Time in familiar zone, hab. session 1	41873.03	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	17765.83	2	1	25	0	1.00e+00	Atg4c Retreg2
Total zone transitions, hab. session 1	1818.53	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	849.35	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 1	571.33	2	1	25	0	1.00e+00	Ccny Retreg2
Time in familiar zone, hab. session 2	23379.25	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	12466.05	2	1	25	0	1.00e+00	Atg4c Retreg2
Total zone transitions, hab. session 2	280.53	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 2	36.26	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Locomotion velocity, hab. session 2	77.91	2	1	25	0	1.00e+00	Ccny Retreg2
Novel to familiar place preference ratio	18509.23	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Novelty place preference	18134.07	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Time in novel zone, NPP test	13621.41	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Total zone transitions, NPP test	8230.03	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, NPP test	3566.83	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotion velocity, NPP test	2031.76	2	2	50	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever latency	1101.84	2	1	25	0	1.00e+00	Atg4c Retreg2
Pavlov. Cond. magazine entry latency	6.56	2	0	0	0	1.00e+00	Atg4c Ccny
Pavlov. Cond. change in total contacts	2273.55	2	1	25	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. index score	888.06	2	1	25	0	1.00e+00	Atg4c Retreg2
Pavlov. Cond. latency score	923.21	2	1	25	0	1.00e+00	Atg4c Retreg2
Pavlov. Cond. lever contacts	1519.97	2	1	25	0	1.00e+00	Atg4c Retreg2
Pavlov. Cond. magazine entry number	726.14	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Pavlov. Cond. intertrial magazine entries	524.02	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	973.09	2	1	25	0	1.00e+00	Atg4c Retreg2
Pavlov. Cond. response bias	1308.04	2	1	25	0	1.00e+00	Atg4c Retreg2
Bone: apparent density	22268.03	1	1	25	0	1.00e+00	Retreg2
Bone surface	25125.6	1	1	25	0	1.00e+00	Retreg2
Bone volume	33831.7	1	1	25	0	1.00e+00	Retreg2
Bone: connectivity density	7098.55	1	1	25	0	1.00e+00	Retreg2
Bone: cortical apparent density	22635.68	2	1	25	0	1.00e+00	Ccny Retreg2
Bone: cortical area	18930.98	1	1	25	0	1.00e+00	Retreg2
Bone: cortical porosity	1837.29	1	1	25	0	1.00e+00	Retreg2
Bone: cortical porosity	4807.78	1	1	25	0	1.00e+00	Retreg2
Bone: cortical thickness	1627.26	1	1	25	0	1.00e+00	Retreg2
Bone: cortical thickness	12190.6	1	1	25	0	1.00e+00	Retreg2
Bone: cortical tissue density	24229.43	2	1	25	0	1.00e+00	Ccny Retreg2
Bone: elastic displacement	29626.25	1	1	25	0	1.00e+00	Retreg2
Bone: elastic work	1494.59	1	1	25	0	1.00e+00	Retreg2
Bone: endosteal estimation	35257.61	1	1	25	0	1.00e+00	Retreg2
Bone: endosteal perimeter	44697.39	1	1	25	0	1.00e+00	Retreg2
Bone: final force	7031.22	1	1	25	0	1.00e+00	Retreg2
Bone: final moment	1042.62	1	1	25	0	1.00e+00	Retreg2
Bone: marrow area	37067.95	1	1	25	0	1.00e+00	Retreg2
Bone: maximum diameter	24401.62	1	1	25	0	1.00e+00	Retreg2
Bone: maximum force	34553.99	1	1	25	0	1.00e+00	Retreg2
Bone: maximum moment	24715.64	1	1	25	0	1.00e+00	Retreg2
Bone: minimum diameter	17196.64	1	1	25	0	1.00e+00	Retreg2
Bone: periosteal estimation	38190.5	1	1	25	0	1.00e+00	Retreg2
Bone: periosteal perimeter	43183.28	1	1	25	0	1.00e+00	Retreg2
Bone: post-yield work	50847.58	1	1	25	0	1.00e+00	Retreg2
Bone: stiffness	35564.91	1	1	25	0	1.00e+00	Retreg2
Bone: tissue strength	12264.67	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular number	41138.39	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular spacing	31287.85	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular thickness	33264.33	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular tissue density	26819.29	2	2	50	0	1.00e+00	Ccny Retreg2
Breakpoint value in progressive ratio session	56221.29	2	1	25	0	1.00e+00	Ccny Retreg2
Distance traveled after self-admin	25247.24	4	3	75	1	4.42e-05	Atg4c Ccny Retreg2 Rnf151
Delta time in closed arm before/after self-admin	694.2	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Delta time in open arm before/after self-admin	18300.08	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Diff in mean of infusions in LGA sessions	54255.46	2	2	50	0	1.00e+00	Atg4c Retreg2
Extinction: sum of active levers before priming	30584.81	3	2	50	0	1.00e+00	Ccny Retreg2 Rnf151
Active lever presses in extinction session 6	1673.08	2	2	50	0	1.00e+00	Ccny Retreg2
Delta distance traveled before/after self-admin	6292.84	2	2	50	0	1.00e+00	Ccny Retreg2
Delta ambulatory time before/after self-admin	24028.59	4	2	50	-1	2.77e-04	Atg4c Ccny Retreg2 Rnf151
Time in closed arm before self-admin	29431.57	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Time in closed arm after self-admin	9901.19	2	2	50	0	1.00e+00	Ccny Retreg2
Time in open arm before self-admin	11583.68	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Time in open arm after self-admin	981.98	2	2	50	0	1.00e+00	Ccny Retreg2
Sum of active levers in priming session hrs 5-6	1943.55	2	1	25	0	1.00e+00	Retreg2 Rnf151
Time to tail flick, vehicle, before self-admin	25931.02	2	2	50	0	1.00e+00	Ccny Retreg2
Time to tail flick, vehicle, after self-admin	59159.07	2	2	50	0	1.00e+00	Ccny Retreg2
Time to tail flick, test, before self-admin	10943.94	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Time to tail flick, test, after self-admin	2994.46	2	2	50	0	1.00e+00	Ccny Retreg2
Delta time to tail flick, vehicle, before/after SA	18449.53	2	2	50	0	1.00e+00	Ccny Retreg2
Delta time to tail flick, test, before/after SA	28423.85	2	1	25	0	1.00e+00	Ccny Retreg2
Ambulatory time before self-admin	42791.79	4	4	100	1	1.31e-05	Atg4c Ccny Retreg2 Rnf151
Ambulatory time after self-admin	22092.11	4	3	75	1	4.78e-05	Atg4c Ccny Retreg2 Rnf151
Total heroin consumption	370.51	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Area under the delay curve	27213.84	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Delay disc. indifference point, 0s delay	4741.82	2	1	25	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 16s delay	24967.07	3	3	75	0	1.00e+00	Atg4c Ccny Retreg2
Delay disc. indifference point, 2s delay	282.83	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Delay disc. indifference point, 24s delay	33351.56	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Delay disc. indifference point, 4s delay	876.78	3	3	75	0	1.00e+00	Atg4c Ccny Retreg2
Delay disc. indifference point, 8s delay	50716.77	2	1	25	0	1.00e+00	Atg4c Retreg2
Delay discount exponential model param	20081.61	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Delay discount hyperbolic model param	22870.65	2	2	50	0	1.00e+00	Atg4c Retreg2
Fecal boli incidents, locomotor time 1	50057.89	3	1	25	0	1.00e+00	Atg4c Ccny Retreg2
Change in fecal boli incidents, locomotor task	11821.21	2	2	50	0	1.00e+00	Ccny Retreg2
Time >=10cm from walls, locomotor time 1	16439.58	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Bouts of movement, locomotor time 1	20842.46	2	2	50	0	1.00e+00	Ccny Retreg2
Total resting periods, locomotor time 1	5936.78	2	2	50	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 1	37983.55	2	1	25	0	1.00e+00	Ccny Retreg2
Distance moved, locomotor task time 1	79651.82	2	2	50	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 1	219061.96	1	1	25	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	80995.71	2	1	25	0	1.00e+00	Ccny Retreg2
Bouts of movement, locomotor time 2	87164.71	2	2	50	0	1.00e+00	Ccny Retreg2
Total resting periods, locomotor time 2	95051.56	2	2	50	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 2	27935.34	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Distance moved, locomotor task time 2	11481.53	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Vertical activity count, locomotor time 2	34621.5	4	2	50	-1	1.40e-04	Atg4c Ccny Retreg2 Rnf151
Weight adjusted by age	54018.9	3	2	50	0	1.00e+00	Ccny Retreg2 Rnf151
Seeking ratio, delayed vs. immediate footshock	24709.08	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber	8161.06	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber post-restriction	77324.49	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio	52650.81	3	2	50	0	1.00e+00	Atg4c Ccny Retreg2
Food seeking constrained by brief footshock	3673.85	2	1	25	0	1.00e+00	Atg4c Retreg2
Seeking ratio, punishment vs. effort	59148.59	2	2	50	0	1.00e+00	Ccny Retreg2
Run reversals in cocaine runway, females	18598.36	2	1	25	0	1.00e+00	Ccny Retreg2
Run reversals in cocaine runway, males	14942.17	2	1	25	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway	29317.55	2	2	50	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway, F	28379.24	1	1	25	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	3675.36	2	2	50	0	1.00e+00	Ccny Retreg2
Co content in liver	4721.74	1	1	25	0	1.00e+00	Retreg2
Cu content in liver	162.43	1	1	25	0	1.00e+00	Retreg2
Fe content in liver	5656.2	1	1	25	0	1.00e+00	Retreg2
K content in liver	6593.53	1	1	25	0	1.00e+00	Retreg2
Mg content in liver	24493.99	1	1	25	0	1.00e+00	Retreg2
Mn content in liver	4374.36	1	1	25	0	1.00e+00	Retreg2
Na content in liver	16641.94	1	1	25	0	1.00e+00	Retreg2
Rb content in liver	428.45	1	1	25	0	1.00e+00	Retreg2
Zn content in liver	15755.62	1	1	25	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.03
Adipose	alternative TSS	0	0	0.94
Adipose	gene expression	0	0	1.03
Adipose	isoform ratio	0	0	0.96
Adipose	intron excision ratio	0	0	0.98
Adipose	mRNA stability	0	0	1.09
BLA	alternative polyA	0	0	1.12
BLA	alternative TSS	0	0	1.02
BLA	gene expression	0	0	1.06
BLA	isoform ratio	0	0	1.06
BLA	intron excision ratio	0	0	1.07
BLA	mRNA stability	0	0	1.06
Brain	alternative polyA	0	0	1.07
Brain	alternative TSS	0	0	0.99
Brain	gene expression	0	0	1.06
Brain	isoform ratio	0	0	1.03
Brain	intron excision ratio	0	0	1.04
Brain	mRNA stability	0	0	1.05
Eye	alternative polyA	0	0	0.88
Eye	alternative TSS	0	0	0.97
Eye	gene expression	0	0	1.07
Eye	isoform ratio	0	0	1
Eye	intron excision ratio	0	0	1.04
Eye	mRNA stability	0	0	1.04
IC	alternative polyA	0	0	1.05
IC	alternative TSS	0	0	0.95
IC	gene expression	0	0	1.06
IC	isoform ratio	0	0	1.06
IC	intron excision ratio	1	0	1.11
IC	mRNA stability	0	0	1.07
IL	alternative polyA	0	0	1.1
IL	alternative TSS	0	0	1.09
IL	gene expression	0	0	1.07
IL	isoform ratio	0	0	1.1
IL	intron excision ratio	0	0	1.23
IL	mRNA stability	0	0	1.02
LHb	alternative polyA	0	0	1.09
LHb	alternative TSS	0	0	1.03
LHb	gene expression	0	0	1.05
LHb	isoform ratio	0	0	1.07
LHb	intron excision ratio	0	0	1.09
LHb	mRNA stability	0	0	1.02
Liver	alternative polyA	0	0	0.99
Liver	alternative TSS	0	0	0.98
Liver	gene expression	0	0	1.05
Liver	isoform ratio	0	0	1.03
Liver	intron excision ratio	0	0	1.04
Liver	mRNA stability	1	0	1.05
NAcc	alternative polyA	1	0	82.86
NAcc	alternative TSS	0	0	1.06
NAcc	gene expression	0	0	1.07
NAcc	isoform ratio	0	0	1.07
NAcc	intron excision ratio	0	0	1.06
NAcc	mRNA stability	0	0	1.05
OFC	alternative polyA	0	0	1.05
OFC	alternative TSS	0	0	1.07
OFC	gene expression	0	0	1.06
OFC	isoform ratio	0	0	1.14
OFC	intron excision ratio	0	0	1.15
OFC	mRNA stability	0	0	1.04
PL	alternative polyA	0	0	1.16
PL	alternative TSS	0	0	1.03
PL	gene expression	0	0	1.08
PL	isoform ratio	0	0	1.07
PL	intron excision ratio	0	0	1.07
PL	mRNA stability	0	0	1.06
pVTA	alternative polyA	0	0	1.06
pVTA	alternative TSS	0	0	1
pVTA	gene expression	1	0	1.1
pVTA	isoform ratio	0	0	1.08
pVTA	intron excision ratio	0	0	1.1
pVTA	mRNA stability	0	0	1.06
RMTg	alternative polyA	0	0	0.96
RMTg	alternative TSS	0	0	1.01
RMTg	gene expression	0	0	1.1
RMTg	isoform ratio	0	0	1.08
RMTg	intron excision ratio	0	0	1.08
RMTg	mRNA stability	0	0	1.06