Best TWAS P=1.71e-09 · Best GWAS P=2.46e-09 conditioned to 1.64e-01
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Tenm4 | alternative TSS | XM_039113170.1 | 0.08 | 3248 | 0.02 | 5.9e-03 | -5.72 | 1.05e-08 | 0.32 | FALSE |
| Adipose | Tenm4 | isoform ratio | XM_039113176.1 | 0.08 | 1 | 0.04 | 2.4e-05 | 5.74 | 9.70e-09 | 0.41 | FALSE |
| BLA | Tenm4 | intron excision ratio | chr1_150700925_150781008 | 0.11 | 3248 | 0.08 | 4.8e-05 | 5.2 | 1.95e-07 | 0.59 | FALSE |
| Brain | Tenm4 | intron excision ratio | chr1_151150960_151158532 | 0.06 | 1 | 0 | 1.2e-01 | 5.37 | 7.91e-08 | 0.03 | FALSE |
| NAcc | Tenm4 | gene expression | Tenm4 | 0.05 | 3248 | 0.02 | 7.5e-04 | 6.02 | 1.71e-09 | 0.62 | TRUE |
| NAcc | Tenm4 | intron excision ratio | chr1_150700925_150781008 | 0.17 | 1 | 0.08 | 5.1e-10 | -5.36 | 8.23e-08 | 0.38 | FALSE |
| PL | Tenm4 | intron excision ratio | chr1_150845205_150898763 | 0.06 | 1 | 0.04 | 3.3e-05 | -5.4 | 6.81e-08 | 0.16 | FALSE |