Hub : Traits

Light reinforcement 2

Light reinforcement, proportion of active snout-poke responses for 5-sec light onset to the total active and inactive responses in the last three 18-minute sessions during the light reinforcement phase for males and females [proportion]

Tags: Behavior · Light reinforcement

Project: p50_david_dietz

4 loci · 4 genes with independent associations · 11 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr1	149923636	152140050	8	1	3.92e-09	2.60e-09	1.00e+00	Ctsc
2	chr8	117463629	118343328	1	1	4.03e-21	7.67e-02	1.00e+00	Mst1
3	chr9	83390749	84777604	1	1	0.00e+00	5.60e-02	1.00e+00	Retreg2
4	chr17	61510864	62906219	1	1	9.09e-16	5.83e-02	1.32e-01	Ccny

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	866.87	1	1	25	0	1.00e+00	Retreg2
BMI without tail	28623.89	2	1	25	0	1.00e+00	Ccny Retreg2
Body weight	6.47	2	1	25	0	1.00e+00	Mst1 Retreg2
Epididymis fat weight	12105.07	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Glucose	336.01	2	2	50	0	1.00e+00	Mst1 Retreg2
Heart weight	3065.65	1	1	25	0	1.00e+00	Retreg2
Left kidney weight	18350.19	3	1	25	0	1.00e+00	Ccny Grm5 Retreg2
Right kidney weight	13474.83	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Tail length	28919.24	1	1	25	0	1.00e+00	Retreg2
Length with tail	747.9	2	2	50	0	1.00e+00	Mst1 Retreg2
Length without tail	15751.64	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Liver weight, left	1755.51	2	2	50	0	1.00e+00	Mst1 Retreg2
Liver weight, right	44.57	2	2	50	0	1.00e+00	Mst1 Retreg2
Parametrial fat weight	181.56	1	1	25	0	1.00e+00	Retreg2
Retroperitoneal fat weight	1985.63	2	2	50	0	1.00e+00	Mst1 Retreg2
Intraocular pressure	702.43	5	1	25	0.98	1.99e-10	Ctsc Grm5 LOC102554680 Retreg2 Tyr
Extensor digitorum longus weight	541.05	2	1	25	0	1.00e+00	Mst1 Retreg2
Soleus weight	20.71	1	1	25	0	1.00e+00	Retreg2
Tibialis anterior weight	1158.38	1	1	25	0	1.00e+00	Retreg2
Tibia length	396.37	2	2	50	0	1.00e+00	Mst1 Retreg2
Number of licking bursts	67424.86	1	1	25	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	11843.69	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Times rat made contact with spout	71.66	1	1	25	0	1.00e+00	Retreg2
Mean time between licks in bursts	12407.11	4	1	25	-1	8.17e-09	Ctsc Grm5 LOC102554680 Retreg2
Mean num. licks in bursts	56750.08	1	1	25	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	14881.26	2	1	25	0	1.00e+00	Mst1 Retreg2
Water consumed over 24 hours	11394.32	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging indifference point 0 sec	19591.07	2	1	25	0	1.00e+00	Mst1 Retreg2
Patch foraging indifference point AUC	16749.7	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Indifference point function ln k	18611.12	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Indifference point function log k	18611.12	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging total patch changes 0 sec	20977.37	2	1	25	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 12 sec	801.08	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging total patch changes 18 sec	20236.6	2	2	50	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 24 sec	24952.35	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging total patch changes 6 sec	3901.9	2	1	25	0	1.00e+00	Ccny Retreg2
Patch foraging time to switch 0 sec	5120.32	5	1	25	-0.99	2.12e-11	Ctsc Grm5 LOC102554680 Mst1 Retreg2
Patch foraging water rate 0 sec	20145.6	3	1	25	0	1.00e+00	Ctsc Grm5 Retreg2
Patch foraging water rate 12 sec	4423.76	6	3	75	0.99	2.87e-13	Ccny Ctsc Grm5 LOC102554680 Mst1 Retreg2
Patch foraging water rate 18 sec	2126.11	6	4	100	0.98	1.25e-11	Ctsc Grm5 LOC102554680 Mst1 Retreg2 Tyr
Patch foraging water rate 24 sec	122.11	5	1	25	-0.98	2.07e-06	Ctsc Grm5 LOC102554680 Mst1 Retreg2
Patch foraging water rate 6 sec	91.7	5	2	50	0.94	5.58e-05	Ccny Ctsc Grm5 LOC102554680 Retreg2
Locomotor activity	9.43	5	1	25	-0.99	3.28e-08	Ccny Ctsc Grm5 Mst1 Tyr
Locomotor testing distance	9240.77	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Locomotor testing rearing	31715.18	2	2	50	0	1.00e+00	Mst1 Retreg2
Light reinforcement 1	4153.67	6	2	50	1	1.57e-20	Ccny Ctsc Grm5 LOC102554680 Retreg2 Tyr
Reaction time number correct	31739.87	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time mean minus median	59976.97	2	1	25	0	1.00e+00	Mst1 Retreg2
Reaction time mean minus median AUC	62004.19	2	2	50	0	1.00e+00	Mst1 Retreg2
Reaction time num false alarms	972.45	6	1	25	1	2.42e-23	Ctsc Grm5 LOC102554680 Mst1 Retreg2 Tyr
Reaction time num false alarms AUC	2343.56	5	1	25	1	9.65e-21	Ctsc Grm5 LOC102554680 Mst1 Retreg2
Reaction time trials correct on left	31739.87	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time trials on left	30447.09	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time mean	29724.21	1	1	25	0	1.00e+00	Retreg2
Reaction time mean AUC	38768	1	1	25	0	1.00e+00	Retreg2
Median of all reaction times	7893.84	1	1	25	0	1.00e+00	Retreg2
Reaction time omissions	8364.84	1	1	25	0	1.00e+00	Retreg2
Reaction time false alarm rate	26.87	5	1	25	-0.63	1.13e-02	Ctsc Grm5 LOC102554680 Mst1 Retreg2
Reaction time premature initiation rate	9733.76	1	1	25	0	1.00e+00	Retreg2
Reaction time premature initiations	53743.58	1	1	25	0	1.00e+00	Retreg2
Std. dev. reaction times	30437.76	2	1	25	0	1.00e+00	Mst1 Retreg2
Reaction time trials completed	30447.09	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time trials AUC	31070.91	2	1	25	0	1.00e+00	Ccny Retreg2
Social response proportion	4397.95	2	1	25	0	1.00e+00	Mst1 Retreg2
Social responses	640.25	2	1	25	0	1.00e+00	Mst1 Retreg2
Social time	5828.31	2	1	25	0	1.00e+00	Mst1 Retreg2
Conditioned locomotion	1400.08	1	1	25	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	19128.47	1	1	25	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	18571.31	1	1	25	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	25	0	1.00e+00	Retreg2
Saline control response	1639.18	2	2	50	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active minus inactive responses	7271.32	2	2	50	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active-inactive response ratio	28713.86	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	1165.18	2	2	50	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. inactive responses	5466.41	2	2	50	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever presses	1963.38	2	2	50	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever reinforcers received	243.91	2	1	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever latency	1278.33	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry latency	6738.25	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. change in total contacts	39811.91	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. index score	6407.33	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	8109.24	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever contacts	2689.72	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry number	2097.69	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	17558.57	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	5938.34	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	641.31	2	2	50	0	1.00e+00	Mst1 Retreg2
Conditioned reinforcement - actives	33603.74	3	1	25	0	1.00e+00	Ccny Ctsc Retreg2
Conditioned reinforcement - inactives	21672.46	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Conditioned locomotion	3453.94	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Intermittent access intake day 1-15 change	63945.95	2	2	50	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation	63041.23	2	2	50	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation 2	12071.47	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Intermitt. access day 1 inactive lever presses	60229.82	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Intermitt. access day 15 inactive lever presses	123608.2	1	1	25	0	1.00e+00	Retreg2
Intermitt. access escalation Index	46701.01	2	2	50	0	1.00e+00	Mst1 Retreg2
Intermittent access day 1 total infusions	33063.01	2	1	25	0	1.00e+00	Mst1 Retreg2
Intermittent access day 15 total infusions	48731.91	1	1	25	0	1.00e+00	Retreg2
Intermittent access terminal intake (last 3 days)	24800.59	1	1	25	0	1.00e+00	Retreg2
Intermittent access total infusions	181.04	1	1	25	0	1.00e+00	Retreg2
Intermittent access day 1 locomotion	17487.55	2	1	25	0	1.00e+00	Ccny Retreg2
Intermittent access day 15 total locomotion	42786.58	2	2	50	0	1.00e+00	Ccny Retreg2
Intermittent access total locomotion	62.99	2	1	25	0	1.00e+00	Mst1 Retreg2
Intermittent access standard deviation	38004.24	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Cocaine induced anxiety	34553.78	2	1	25	0	1.00e+00	Ccny Retreg2
Post-drug Anxiety	4753.56	1	1	25	0	1.00e+00	Retreg2
Baseline Anxiety	3359.5	4	1	25	-1	9.12e-15	Ccny Ctsc Grm5 Retreg2
Lifetime Intake	834.23	2	1	25	0	1.00e+00	Ccny Retreg2
Incentive Sensitization - Responses	35678.36	2	1	25	0	1.00e+00	Ccny Retreg2
Incentive Sensitization - Breakpoint	27641.32	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 active lever presses	16000.1	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 breakpoint	15155.7	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 inactive lever presses	31120.43	2	2	50	0	1.00e+00	Mst1 Retreg2
Progressive ratio test 2 active lever presses	7640.52	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 breakpoint	4281.49	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 inactive lever presses	24172.02	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Total sessions with >9 infusions	143.54	7	3	75	0.98	4.53e-10	Ccny Ctsc Grm5 LOC102554680 Mst1 Retreg2 Tyr
Short access day 1 total inactive lever presses	13169.69	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Short access day 10 total inactive lever presses	46316.52	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Short access day 1 total infusions	2965.3	7	2	50	1	9.08e-17	Ccny Ctsc Grm5 LOC102554680 Mst1 Retreg2 Tyr
Short access day 10 total infusions	11366.61	2	2	50	0	1.00e+00	Mst1 Retreg2
Short access total infusions	4403.04	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 1 locomotion	12408.48	2	1	25	0	1.00e+00	Ccny Retreg2
Short access day 10 total locomotion	44094.34	2	1	25	0	1.00e+00	Mst1 Retreg2
Short access total locomotion	9355.68	2	2	50	0	1.00e+00	Mst1 Retreg2
Compulsive drug intake	9345.9	2	1	25	0	1.00e+00	Mst1 Retreg2
One hour access (0.3 mA shock)	1168.72	2	1	25	0	1.00e+00	Ccny Retreg2
One hour access (shock baseline)	54988.81	1	1	25	0	1.00e+00	Retreg2
Number of responses in last shaping day	6821.53	2	1	25	0	1.00e+00	Ccny Retreg2
Context. condit. distance diff. score	212.47	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 1	251.41	5	1	25	-0.99	1.95e-11	Ctsc Grm5 LOC102554680 Retreg2 Tyr
Locomotion distance, session 1	516.6	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 2	208.78	5	2	50	-0.97	6.05e-07	Ctsc Grm5 LOC102554680 Mst1 Retreg2
Locomotion distance, session 2	174.93	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Locomotion velocity, session 3	507.49	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 3	317.26	5	1	25	0.97	4.00e-08	Ctsc Grm5 LOC102554680 Retreg2 Tyr
Stereotopy head waving bouts, day 3	100.35	5	1	25	0.97	2.95e-09	Ctsc Grm5 LOC102554680 Mst1 Retreg2
Stereotopy head waving duration, day 3	1446.08	2	1	25	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, session 7	210.64	2	2	50	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 7	507.07	2	2	50	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving bouts, day 7	2509.72	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	2115.93	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 8	39.51	4	1	25	-0.92	6.00e-06	Ctsc Grm5 LOC102554680 Retreg2
Locomotion distance, session 8	147.88	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization distance	1889.61	2	2	50	0	1.00e+00	Mst1 Retreg2
Degree of sensitization stereotypy	1027.5	2	1	25	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active minus inactive responses	957.65	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	242.03	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	2765.7	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	2347.96	2	1	25	0	1.00e+00	Mst1 Retreg2
Incentive salience index mean	1780.77	2	1	25	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever presses	2666.81	2	2	50	0	1.00e+00	Mst1 Retreg2
Time in familiar zone, hab. session 1	5593.23	2	1	25	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 1	4629.95	2	2	50	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 1	54.86	4	1	25	0.9	1.01e-03	Ctsc Grm5 LOC102554680 Retreg2
Total locomotion distance, hab. session 1	54.62	5	5	125	0.78	6.21e-04	Ctsc Grm5 LOC102554680 Retreg2 Tyr
Locomotion velocity, hab. session 1	47.15	5	5	125	0.71	2.79e-03	Ctsc Grm5 LOC102554680 Retreg2 Tyr
Time in familiar zone, hab. session 2	2966.16	2	2	50	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 2	3208.33	2	2	50	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 2	38.53	2	1	25	0	1.00e+00	Mst1 Retreg2
Total locomotion distance, hab. session 2	37.26	5	5	125	0.35	2.02e-01	Ctsc Grm5 LOC102554680 Retreg2 Tyr
Locomotion velocity, hab. session 2	35.13	5	5	125	0.39	1.49e-01	Ctsc Grm5 LOC102554680 Retreg2 Tyr
Novel to familiar place preference ratio	7678.6	2	1	25	0	1.00e+00	Mst1 Retreg2
Novelty place preference	7474.7	2	1	25	0	1.00e+00	Mst1 Retreg2
Time in novel zone, NPP test	5350.34	2	1	25	0	1.00e+00	Mst1 Retreg2
Total zone transitions, NPP test	1935.62	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, NPP test	151.89	5	5	125	0.91	2.66e-06	Ctsc Grm5 LOC102554680 Retreg2 Tyr
Locomotion velocity, NPP test	101.47	5	5	125	0.86	4.74e-05	Ctsc Grm5 LOC102554680 Retreg2 Tyr
Pavlov. Cond. lever latency	276.98	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. change in total contacts	1037.76	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. index score	214.07	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	224.45	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever contacts	372.95	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry number	250.94	2	1	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	82.71	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	223.77	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	303.26	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: apparent density	5461.77	1	1	25	0	1.00e+00	Retreg2
Bone surface	3109.3	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone volume	4317.38	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: connectivity density	838.02	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: cortical apparent density	12020.36	1	1	25	0	1.00e+00	Retreg2
Bone: cortical area	2335.88	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: cortical porosity	432.96	1	1	25	0	1.00e+00	Retreg2
Bone: cortical porosity	1113.18	1	1	25	0	1.00e+00	Retreg2
Bone: cortical thickness	232.49	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: cortical thickness	1488.54	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: cortical tissue density	13002.58	1	1	25	0	1.00e+00	Retreg2
Bone: elastic displacement	7604.03	1	1	25	0	1.00e+00	Retreg2
Bone: elastic work	195.81	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: endosteal estimation	4459.49	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: endosteal perimeter	5936.33	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: final force	840.18	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: final moment	146.88	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: marrow area	4718.94	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: maximum diameter	3067.59	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: maximum force	4390.32	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: maximum moment	3034.59	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: minimum diameter	2061.38	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: periosteal estimation	4919.52	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: periosteal perimeter	5722.93	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: post-yield work	6843.13	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: stiffness	4554.23	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: tissue strength	2995.95	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular number	10739.78	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular spacing	3991.76	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: trabecular thickness	4257.4	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: trabecular tissue density	7288.79	2	2	50	0	1.00e+00	Mst1 Retreg2
Breakpoint value in progressive ratio session	18809.48	2	1	25	0	1.00e+00	Mst1 Retreg2
Distance traveled before self-admin	25273.33	2	1	25	0	1.00e+00	Ccny Retreg2
Distance traveled after self-admin	16247.09	2	2	50	0	1.00e+00	Ccny Retreg2
Delta time in closed arm before/after self-admin	188.99	2	2	50	0	1.00e+00	Ccny Retreg2
Delta time in open arm before/after self-admin	7570.09	2	1	25	0	1.00e+00	Ccny Retreg2
Diff in mean of infusions in LGA sessions	18336.8	2	2	50	0	1.00e+00	Mst1 Retreg2
Extinction: sum of active levers before priming	9495.75	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Active lever presses in extinction session 6	272.24	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Delta distance traveled before/after self-admin	1480.05	2	1	25	0	1.00e+00	Ccny Retreg2
Delta ambulatory time before/after self-admin	15428.86	2	1	25	0	1.00e+00	Ccny Retreg2
Time in closed arm before self-admin	8974	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Time in closed arm after self-admin	1570.76	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Time in open arm before self-admin	2928.72	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Time in open arm after self-admin	188.09	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Sum of active levers in priming session hrs 5-6	494.14	2	1	25	0	1.00e+00	Retreg2 Tyr
Time to tail flick, vehicle, before self-admin	4498.29	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Time to tail flick, vehicle, after self-admin	21076.92	2	1	25	0	1.00e+00	Ccny Retreg2
Time to tail flick, test, before self-admin	8139.55	1	1	25	0	1.00e+00	Retreg2
Time to tail flick, test, after self-admin	711.65	2	1	25	0	1.00e+00	Ccny Retreg2
Delta time to tail flick, vehicle, before/after SA	3305.45	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Delta time to tail flick, test, before/after SA	7847.8	2	1	25	0	1.00e+00	Mst1 Retreg2
Ambulatory time before self-admin	39445.74	2	1	25	0	1.00e+00	Ccny Retreg2
Ambulatory time after self-admin	8880.01	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Total heroin consumption	134.58	2	2	50	0	1.00e+00	Ccny Retreg2
Area under the delay curve	24791.27	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 0s delay	2159.25	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 16s delay	10986.22	2	1	25	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 2s delay	155.27	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 24s delay	16227.16	2	1	25	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 4s delay	314.57	2	1	25	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 8s delay	33362.4	1	1	25	0	1.00e+00	Retreg2
Delay discount exponential model param	16922.54	1	1	25	0	1.00e+00	Retreg2
Delay discount hyperbolic model param	12277.65	1	1	25	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	61202.36	1	1	25	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	2856.56	2	2	50	0	1.00e+00	Ccny Retreg2
Time >=10cm from walls, locomotor time 1	6510.41	2	1	25	0	1.00e+00	Ccny Retreg2
Bouts of movement, locomotor time 1	5409.06	2	2	50	0	1.00e+00	Ccny Retreg2
Total resting periods, locomotor time 1	1407.78	2	1	25	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 1	22349.64	1	1	25	0	1.00e+00	Retreg2
Distance moved, locomotor task time 1	68821.85	1	1	25	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 1	142354.07	1	1	25	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	71159.6	1	1	25	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 2	41025.7	2	2	50	0	1.00e+00	Ccny Retreg2
Total resting periods, locomotor time 2	49531.53	2	2	50	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 2	25503.09	1	1	25	0	1.00e+00	Retreg2
Distance moved, locomotor task time 2	4250.65	2	2	50	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 2	26786.04	2	1	25	0	1.00e+00	Ccny Retreg2
Weight adjusted by age	35403.57	2	2	50	0	1.00e+00	Ccny Retreg2
Seeking ratio, delayed vs. immediate footshock	6729.38	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber	3903.37	1	1	25	0	1.00e+00	Retreg2
Locomotion in novel chamber post-restriction	65422.89	1	1	25	0	1.00e+00	Retreg2
Progressive ratio	33954	2	2	50	0	1.00e+00	Ccny Retreg2
Food seeking constrained by brief footshock	1875.34	1	1	25	0	1.00e+00	Retreg2
Seeking ratio, punishment vs. effort	41283.25	1	1	25	0	1.00e+00	Retreg2
Run reversals in cocaine runway, females	9406.04	1	1	25	0	1.00e+00	Retreg2
Run reversals in cocaine runway, males	7664.74	1	1	25	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway	4082.42	4	1	25	1	1.98e-05	Ccny Ctsc Grm5 Retreg2
Latency to leave start box in cocaine runway, F	3587.43	2	1	25	0	1.00e+00	Grm5 Retreg2
Latency to leave start box in cocaine runway, M	590.51	3	2	50	0	1.00e+00	Ccny Grm5 Retreg2
Co content in liver	1133.25	1	1	25	0	1.00e+00	Retreg2
Cu content in liver	39.92	1	1	25	0	1.00e+00	Retreg2
Fe content in liver	1344.53	1	1	25	0	1.00e+00	Retreg2
K content in liver	1519.62	1	1	25	0	1.00e+00	Retreg2
Mg content in liver	6026.97	1	1	25	0	1.00e+00	Retreg2
Mn content in liver	1009.39	1	1	25	0	1.00e+00	Retreg2
Na content in liver	4018.36	1	1	25	0	1.00e+00	Retreg2
Rb content in liver	87.87	1	1	25	0	1.00e+00	Retreg2
Zn content in liver	3745.55	1	1	25	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.28
Adipose	alternative TSS	0	0	1.35
Adipose	gene expression	0	0	1.31
Adipose	isoform ratio	0	0	1.26
Adipose	intron excision ratio	0	0	1.28
Adipose	mRNA stability	0	0	1.25
BLA	alternative polyA	0	0	1.33
BLA	alternative TSS	0	0	1.42
BLA	gene expression	0	0	1.32
BLA	isoform ratio	0	0	1.43
BLA	intron excision ratio	0	0	1.36
BLA	mRNA stability	0	0	1.33
Brain	alternative polyA	2	0.1	1.31
Brain	alternative TSS	0	0	1.32
Brain	gene expression	1	0	1.32
Brain	isoform ratio	2	0	1.36
Brain	intron excision ratio	0	0	1.41
Brain	mRNA stability	1	0	1.31
Eye	alternative polyA	0	0	1.37
Eye	alternative TSS	0	0	1.33
Eye	gene expression	0	0	1.31
Eye	isoform ratio	0	0	1.29
Eye	intron excision ratio	0	0	1.34
Eye	mRNA stability	0	0	1.38
IC	alternative polyA	2	0.1	1.32
IC	alternative TSS	0	0	1.4
IC	gene expression	0	0	1.32
IC	isoform ratio	0	0	1.4
IC	intron excision ratio	0	0	1.44
IC	mRNA stability	0	0	1.36
IL	alternative polyA	0	0	1.27
IL	alternative TSS	0	0	1.23
IL	gene expression	1	0	1.32
IL	isoform ratio	0	0	1.32
IL	intron excision ratio	0	0	1.28
IL	mRNA stability	0	0	1.3
LHb	alternative polyA	0	0	1.16
LHb	alternative TSS	0	0	1.17
LHb	gene expression	0	0	1.27
LHb	isoform ratio	0	0	1.35
LHb	intron excision ratio	0	0	1.32
LHb	mRNA stability	0	0	1.33
Liver	alternative polyA	0	0	1.31
Liver	alternative TSS	0	0	1.3
Liver	gene expression	1	0	1.3
Liver	isoform ratio	1	0	1.31
Liver	intron excision ratio	0	0	1.31
Liver	mRNA stability	0	0	1.29
NAcc	alternative polyA	1	0	17.46
NAcc	alternative TSS	0	0	1.34
NAcc	gene expression	2	0	1.34
NAcc	isoform ratio	0	0	1.33
NAcc	intron excision ratio	0	0	1.43
NAcc	mRNA stability	1	0	1.36
OFC	alternative polyA	0	0	1.33
OFC	alternative TSS	0	0	1.31
OFC	gene expression	1	0	1.31
OFC	isoform ratio	0	0	1.4
OFC	intron excision ratio	0	0	1.43
OFC	mRNA stability	0	0	1.34
PL	alternative polyA	0	0	1.35
PL	alternative TSS	0	0	1.32
PL	gene expression	0	0	1.33
PL	isoform ratio	0	0	1.36
PL	intron excision ratio	0	0	1.42
PL	mRNA stability	0	0	1.36
pVTA	alternative polyA	0	0	1.31
pVTA	alternative TSS	0	0	1.37
pVTA	gene expression	1	0	1.34
pVTA	isoform ratio	0	0	1.3
pVTA	intron excision ratio	0	0	1.34
pVTA	mRNA stability	0	0	1.39
RMTg	alternative polyA	0	0	1.45
RMTg	alternative TSS	0	0	1.18
RMTg	gene expression	0	0	1.35
RMTg	isoform ratio	0	0	1.32
RMTg	intron excision ratio	0	0	1.42
RMTg	mRNA stability	0	0	1.25