Thap12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Thap12 0.4 0.21 1.5e-03 0.05 0.06 0.08 0.08 2.0e-02 1.8e-02 6.8e-03 6.6e-03
2 PL isoform ratio NM_001191630.2 0.1 0.06 2.4e-08 0.07 0.07 0.06 0.07 1.5e-08 1.7e-08 2.2e-07 3.9e-08
3 PL isoform ratio XM_039113219.1 0.1 0.06 8.6e-09 0.08 0.08 0.06 0.07 5.0e-09 7.7e-09 1.2e-07 1.5e-08
4 Adipose mRNA stability Thap12 0.07 0.04 4.6e-06 0.04 0.04 0.04 0.04 4.4e-05 8.0e-06 2.0e-05 1.8e-05
5 Brain mRNA stability Thap12 0.08 0.05 4.9e-06 0.06 0.05 0.06 0.06 1.2e-06 2.5e-05 7.9e-06 5.1e-06
6 PL gene expression Thap12 0.11 0.06 2.3e-10 0.09 0.1 0.1 0.1 2.0e-10 3.7e-11 3.1e-11 1.2e-11
7 pVTA alternative TSS XM_039113219.1 0.1 0.08 4.6e-03 0.04 0.02 0.01 0.03 6.8e-03 6.0e-02 1.5e-01 2.5e-02
8 pVTA isoform ratio NM_001191630.2 0.23 0.12 7.0e-07 0.14 0.12 0.12 0.12 1.5e-06 7.3e-06 5.5e-06 8.6e-06
9 pVTA isoform ratio XM_039113219.1 0.23 0.12 1.1e-06 0.14 0.12 0.12 0.12 1.6e-06 6.8e-06 5.9e-06 6.3e-06
10 NAcc mRNA stability Thap12 0.04 0.04 1.4e-03 0.02 0.01 0.01 0.01 3.1e-03 1.2e-02 8.6e-03 1.5e-02
11 Adipose gene expression Thap12 0.08 0.07 1.8e-04 0.03 0.03 0.03 0.03 1.8e-04 2.7e-04 1.9e-04 1.8e-04
12 Brain gene expression Thap12 0.3 0.12 0.0e+00 0.18 0.2 0.2 0.2 2.9e-16 7.6e-19 2.7e-18 3.2e-18
13 BLA gene expression Thap12 0.2 0.13 3.8e-05 0.07 0.09 0.08 0.07 1.9e-04 1.2e-05 2.9e-05 1.1e-04
14 NAcc isoform ratio XM_039113219.1 0.04 0.03 3.5e-04 0.02 0.02 0.03 0.02 2.7e-03 8.0e-04 4.0e-04 8.4e-04
15 NAcc isoform ratio NM_001191630.2 0.04 0.03 7.9e-04 0.02 0.02 0.02 0.02 2.3e-03 9.8e-04 1.6e-03 1.4e-03
16 NAcc gene expression Thap12 0.12 0.06 3.2e-12 0.11 0.11 0.11 0.11 1.4e-12 5.9e-13 5.4e-13 7.1e-13
17 BLA isoform ratio NM_001191630.2 0.13 0.08 2.4e-05 0.05 0.08 0.06 0.08 7.6e-04 7.2e-05 3.3e-04 6.6e-05
18 BLA isoform ratio XM_039113219.1 0.12 0.08 3.7e-05 0.05 0.07 0.06 0.07 1.0e-03 1.1e-04 5.3e-04 1.0e-04
19 OFC gene expression Thap12 0.21 0.14 3.9e-03 0.09 0.06 0.07 0.06 3.5e-03 1.7e-02 1.1e-02 1.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.10.10.6-0.40.1-0.10.30.0-0.40.6-0.20.20.00.8-0.00.00.3-0.10.3-0.30.30.1
Area under the delay curve0.00.10.20.2-0.10.1-0.20.10.4-0.2-0.00.00.1-0.20.30.2-0.2-0.0-0.50.1-0.1-0.4
BMI with tail0.20.62.9-0.9-0.10.10.7-0.0-1.2-0.3-0.20.2-0.10.1-1.3-1.1-0.3-0.21.3-0.40.41.7
BMI without tail1.42.86.7-0.81.3-1.31.01.4-1.6-1.01.1-1.11.2-1.0-1.8-1.6-1.7-2.12.5-2.42.42.6
Body weight0.52.14.7-0.41.0-1.00.81.2-1.1-1.30.9-0.91.0-1.1-1.5-1.5-2.0-2.02.0-2.02.02.2
Weight adjusted by age0.91.02.20.41.1-1.1-0.11.1-0.1-1.11.3-1.30.9-1.2-0.3-0.3-1.5-1.40.7-1.41.40.7
Bone surface1.42.54.11.32.0-2.0-1.31.91.2-1.41.6-1.61.8-1.21.41.3-1.7-1.9-0.8-2.02.0-0.9
Bone volume0.71.22.80.71.4-1.4-0.61.30.5-0.91.1-1.11.3-0.80.60.6-1.2-1.5-0.1-1.61.7-0.2
Breakpoint value in progressive ratio session0.40.41.2-0.5-0.70.70.3-0.6-0.30.6-1.01.0-1.10.6-0.3-0.30.70.70.20.7-0.70.1
Number of licking bursts4.04.76.5-2.5-2.22.22.5-2.0-2.62.1-2.02.0-2.12.3-2.4-2.51.51.72.31.7-1.72.4
Context. condit. distance diff. score2.12.65.01.52.1-2.1-2.22.11.3-1.01.4-1.41.5-0.81.92.2-0.8-1.0-1.7-1.51.4-1.2
Locomotion velocity, session 10.60.72.30.2-1.21.20.2-1.20.50.3-0.40.4-0.70.1-0.1-0.20.41.2-0.31.5-1.5-0.9
Locomotion distance, session 10.40.51.50.90.2-0.2-1.00.21.2-0.70.4-0.40.0-0.80.90.9-0.30.2-1.20.4-0.4-1.2
Locomotion velocity, session 20.20.20.80.6-0.40.40.1-0.30.7-0.50.2-0.20.2-0.9-0.1-0.2-0.5-0.0-0.10.3-0.3-0.7
Locomotion distance, session 20.20.20.70.70.1-0.1-0.50.20.8-0.70.4-0.40.2-0.80.30.3-0.5-0.1-0.40.0-0.0-0.8
Locomotion velocity, session 30.20.20.60.60.3-0.3-0.80.40.6-0.30.4-0.40.1-0.60.30.6-0.20.2-0.5-0.10.1-0.7
Locomotion distance, session 30.50.51.50.90.5-0.5-1.20.51.1-0.60.4-0.40.2-0.51.01.2-0.20.2-1.20.0-0.1-1.2
Stereotopy head waving bouts, day 30.20.30.7-0.5-0.50.50.8-0.5-0.50.5-0.50.5-0.40.1-0.7-0.80.30.10.80.2-0.20.5
Stereotopy head waving duration, day 30.30.30.70.80.5-0.5-0.60.40.8-0.30.6-0.60.8-0.60.60.7-0.2-0.3-0.6-0.30.3-0.8
Locomotion velocity, session 70.30.30.5-0.6-0.60.60.4-0.3-0.60.6-0.70.7-0.70.7-0.6-0.40.60.70.50.4-0.40.5
Locomotion distance, session 70.10.10.4-0.1-0.20.20.3-0.0-0.4-0.10.2-0.2-0.00.2-0.6-0.4-0.40.00.5-0.20.20.6
Stereotopy head waving bouts, day 71.21.32.91.51.0-1.0-1.51.01.6-0.80.6-0.60.6-1.21.61.6-0.6-0.5-1.6-0.40.4-1.7
Stereotopy head waving duration, day 71.92.33.71.91.5-1.5-1.71.51.9-1.41.3-1.31.3-1.71.81.7-1.2-1.2-1.7-1.01.0-1.8
Locomotion velocity, session 81.72.13.41.51.6-1.6-1.61.61.6-1.01.5-1.51.5-0.91.81.8-1.0-1.2-1.6-1.11.1-1.6
Locomotion distance, session 81.42.03.51.71.6-1.6-1.91.61.6-1.31.3-1.31.2-1.31.61.8-1.0-0.9-1.6-1.00.9-1.5
Degree of sensitization distance0.60.62.0-0.30.1-0.10.90.2-0.9-0.20.4-0.40.5-0.0-1.0-1.1-0.8-1.01.3-0.80.91.4
Degree of sensitization stereotypy3.13.46.82.41.6-1.6-2.41.62.5-1.61.2-1.21.1-1.82.62.4-1.1-0.9-2.6-0.70.7-2.5
Conditioned locomotion0.10.10.20.1-0.30.3-0.1-0.10.10.4-0.40.4-0.30.20.20.30.40.4-0.30.3-0.3-0.3
Cocaine response after cond. corrected1.21.32.5-1.0-1.31.31.4-1.4-1.20.7-1.01.0-1.10.8-1.3-1.60.40.81.11.2-1.21.4
Cocaine response after cond. not corrected0.40.41.1-0.2-0.80.80.7-1.0-0.40.3-0.60.6-0.80.4-0.5-0.70.00.70.21.0-1.00.5
Cocaine response before conditioning0.91.12.61.30.9-0.9-1.40.91.5-0.60.7-0.70.5-0.61.61.6-0.5-0.3-1.5-0.20.2-1.6
Saline control response1.92.44.41.91.5-1.5-1.21.51.5-2.01.6-1.61.5-2.11.10.9-2.1-1.8-0.9-1.51.5-1.0
Bone: connectivity density0.20.30.80.20.6-0.6-0.50.60.40.20.3-0.30.50.40.80.90.2-0.3-0.5-0.50.5-0.8
Bone: cortical apparent density0.81.02.2-1.0-1.01.01.5-1.3-1.21.0-0.80.8-0.80.9-1.1-1.40.50.41.30.8-0.71.2
Bone: cortical area0.81.22.80.41.5-1.5-0.61.30.1-1.21.2-1.21.2-0.80.40.4-1.4-1.5-0.0-1.61.70.5
Bone: cortical porosity1.01.02.41.50.7-0.7-1.40.81.6-0.70.6-0.60.7-1.11.31.4-0.6-0.2-1.5-0.10.1-1.5
Bone: cortical porosity0.60.72.11.30.3-0.3-1.10.51.4-0.50.3-0.30.4-0.91.01.1-0.50.1-1.30.1-0.2-1.4
Bone: cortical thickness0.10.21.0-0.8-0.20.20.5-0.3-0.90.4-0.30.3-0.30.6-0.5-0.50.20.20.50.1-0.11.0
Bone: cortical thickness0.10.10.30.30.1-0.1-0.50.10.3-0.50.1-0.10.1-0.30.30.4-0.4-0.0-0.50.1-0.1-0.1
Bone: cortical tissue density0.81.12.2-1.0-1.01.01.5-1.3-1.21.1-0.90.9-0.90.9-1.1-1.40.60.51.20.8-0.81.1
Condit. Reinf. active minus inactive responses0.40.51.2-0.10.7-0.70.20.7-0.6-0.40.5-0.50.6-0.4-0.5-0.4-0.9-0.90.8-1.01.10.9
Condit. Reinf. active-inactive response ratio1.01.12.90.31.4-1.4-0.31.3-0.2-0.71.1-1.11.2-0.60.20.2-1.2-1.50.4-1.71.70.6
Condit. Reinf. active responses0.20.20.9-0.30.0-0.00.50.1-0.70.10.0-0.00.0-0.0-0.8-0.7-0.5-0.20.9-0.30.40.9
Condit. Reinf. inactive responses0.30.40.6-0.4-0.80.80.5-0.7-0.40.5-0.60.6-0.70.2-0.7-0.60.20.70.40.7-0.70.3
Incentive salience index mean0.30.30.8-0.10.5-0.50.20.6-0.5-0.30.3-0.30.3-0.3-0.6-0.4-0.7-0.70.8-0.90.90.8
Condit. Reinf. lever presses0.00.00.2-0.00.0-0.00.10.2-0.10.1-0.20.2-0.2-0.2-0.3-0.1-0.2-0.20.4-0.30.3-0.0
Condit. Reinf. active minus inactive responses6.58.011.82.83.1-3.1-2.73.02.3-3.43.3-3.33.2-3.02.42.2-3.2-2.9-2.2-2.72.7-1.4
Condit. Reinf. active-inactive response ratio0.80.81.70.91.0-1.0-1.11.00.7-1.31.0-1.00.9-1.00.70.8-1.0-0.8-0.8-0.80.8-0.4
Condit. Reinf. active responses9.513.219.43.63.9-3.9-3.23.83.0-4.44.2-4.24.1-4.02.92.6-4.3-4.0-2.4-3.63.6-1.8
Condit. Reinf. inactive responses6.47.912.52.93.0-3.0-2.12.72.4-3.33.2-3.23.2-3.42.21.7-3.5-3.4-1.6-2.92.9-1.5
Condit. Reinf. lever presses20.527.832.95.75.5-5.5-5.55.45.5-5.75.5-5.55.5-5.45.55.1-5.2-5.0-4.8-4.64.5-4.5
Condit. Reinf. lever reinforcers received10.314.520.93.84.1-4.1-3.54.03.2-4.64.4-4.44.3-4.23.22.8-4.4-4.1-2.7-3.73.7-2.1
Conditioned reinforcement - actives1.81.84.01.80.9-0.9-1.81.11.9-1.11.0-1.01.0-1.11.81.9-0.8-0.5-2.0-0.60.5-1.9
Conditioned reinforcement - inactives0.30.30.9-0.1-0.90.90.6-0.9-0.20.5-0.40.4-0.50.5-0.4-0.50.40.60.10.7-0.70.0
Conditioned locomotion1.31.63.91.80.6-0.6-1.70.61.9-1.21.0-1.01.0-1.21.61.7-0.7-0.2-2.0-0.20.2-1.9
Patch foraging indifference point 0 sec5.79.211.53.23.3-3.3-3.33.43.0-3.02.8-2.83.1-3.03.13.2-2.8-2.9-2.7-3.03.0-2.4
Patch foraging indifference point AUC0.20.20.60.10.6-0.6-0.00.5-0.1-0.30.3-0.30.4-0.30.2-0.0-0.6-0.80.1-0.70.70.3
Delay disc. indifference point, 0s delay0.50.61.20.90.5-0.5-0.70.50.8-1.10.9-0.91.1-1.10.60.5-1.1-0.7-0.7-0.40.4-0.6
Delay disc. indifference point, 16s delay0.20.20.3-0.1-0.50.5-0.0-0.30.30.3-0.50.5-0.60.30.20.20.40.5-0.30.6-0.6-0.6
Delay disc. indifference point, 2s delay1.21.31.91.30.8-0.8-1.21.01.3-1.21.3-1.31.2-1.21.21.1-1.0-0.8-1.4-0.60.7-1.2
Delay disc. indifference point, 24s delay0.90.81.7-1.2-0.80.81.0-0.8-0.91.0-1.31.3-1.11.0-0.8-0.90.60.70.80.6-0.70.7
Delay disc. indifference point, 4s delay0.50.62.01.00.2-0.2-0.40.30.8-1.31.0-1.00.7-1.30.2-0.0-1.4-0.6-0.3-0.20.3-0.4
Delay disc. indifference point, 8s delay0.30.30.90.50.5-0.5-0.70.80.6-0.30.2-0.20.4-0.30.90.8-0.3-0.4-1.0-0.40.4-0.7
Indifference point function ln k1.11.53.41.40.8-0.8-1.80.81.7-1.10.9-0.91.1-1.01.61.8-0.4-0.2-1.8-0.30.2-1.8
Indifference point function log k1.11.53.41.40.8-0.8-1.80.81.7-1.10.9-0.91.1-1.01.61.8-0.4-0.2-1.8-0.30.2-1.8
Patch foraging total patch changes 0 sec4.77.59.43.03.0-3.0-3.03.12.7-2.72.5-2.52.7-2.72.82.9-2.6-2.6-2.5-2.62.7-2.2
Patch foraging total patch changes 12 sec1.72.24.61.02.0-2.0-1.11.90.7-1.31.3-1.31.5-1.40.91.0-1.6-2.0-0.5-2.22.2-0.2
Patch foraging total patch changes 18 sec2.33.04.91.61.9-1.9-1.32.01.2-1.81.9-1.92.0-1.91.21.2-2.0-2.1-0.7-2.12.2-0.7
Patch foraging total patch changes 24 sec0.50.61.61.00.8-0.8-0.60.60.6-1.10.9-0.90.9-1.20.30.3-1.3-0.9-0.3-0.70.8-0.2
Patch foraging total patch changes 6 sec1.42.03.31.31.8-1.8-1.71.51.3-1.11.2-1.21.4-0.91.81.8-0.9-1.2-1.6-1.41.5-1.1
Patch foraging time to switch 0 sec4.67.18.7-2.8-3.03.02.6-2.9-2.52.8-2.72.7-2.92.8-2.4-2.42.72.82.02.7-2.72.0
Patch foraging water rate 0 sec3.45.56.72.52.5-2.5-2.52.52.4-2.62.3-2.32.5-2.52.32.3-2.2-2.1-2.1-2.12.1-2.0
Patch foraging water rate 12 sec2.13.35.32.31.6-1.6-2.01.52.2-1.92.0-2.01.9-2.01.81.9-1.6-1.3-1.8-1.41.4-2.0
Patch foraging water rate 18 sec0.81.01.61.01.3-1.3-0.91.01.0-1.11.1-1.11.0-1.20.70.8-0.9-1.0-0.6-1.11.1-0.8
Patch foraging water rate 24 sec0.70.92.51.00.8-0.8-1.40.51.4-0.70.7-0.70.7-0.91.21.5-0.1-0.1-1.4-0.30.3-1.6
Patch foraging water rate 6 sec0.71.02.11.11.0-1.0-1.30.81.3-0.60.6-0.60.8-0.71.31.4-0.4-0.5-1.3-0.60.5-1.4
Seeking ratio, delayed vs. immediate footshock2.02.33.2-1.8-1.61.61.6-1.8-1.51.5-1.41.4-1.51.5-1.6-1.61.31.61.31.5-1.41.2
Distance traveled before self-admin0.30.30.5-0.7-0.70.70.7-0.5-0.60.6-0.40.4-0.50.7-0.5-0.60.50.40.50.4-0.40.5
Distance traveled after self-admin1.51.62.9-1.1-1.71.70.9-1.5-0.61.3-1.31.3-1.41.3-0.6-0.71.51.70.21.7-1.70.2
Extensor digitorum longus weight0.20.82.5-0.90.5-0.50.80.5-1.2-0.30.1-0.10.40.2-0.9-0.9-0.5-1.11.5-1.21.21.6
Bone: elastic displacement1.41.62.7-1.5-1.21.21.2-1.5-1.31.4-1.31.3-1.11.6-1.1-1.01.41.40.91.3-1.31.0
Bone: elastic work1.82.43.9-1.7-1.61.61.1-1.6-1.21.8-1.91.9-1.72.0-0.8-0.81.91.80.71.7-1.60.6
Bone: endosteal estimation1.32.95.71.22.1-2.1-0.92.00.8-1.81.8-1.81.7-1.90.70.6-2.2-2.4-0.1-2.32.4-0.1
Bone: endosteal perimeter2.14.36.81.82.5-2.5-1.52.31.6-2.32.2-2.22.2-2.31.41.3-2.2-2.6-0.9-2.52.6-1.1
Epididymis fat weight0.81.87.0-1.6-0.30.31.7-0.3-2.1-0.1-0.40.4-0.40.1-2.2-2.2-0.4-0.62.5-0.60.72.6
Delta time in closed arm before/after self-admin0.60.62.4-0.80.0-0.01.10.2-1.10.2-0.10.10.10.2-1.0-1.1-0.2-0.71.6-0.80.71.4
Delta time in open arm before/after self-admin2.62.53.61.71.9-1.9-1.51.71.4-1.61.5-1.51.5-1.61.31.4-1.6-1.7-1.2-1.71.7-1.1
Diff in mean of infusions in LGA sessions3.63.95.2-2.3-1.91.92.1-1.8-2.22.0-2.22.2-2.21.9-2.2-2.11.61.72.11.5-1.42.0
Delay discount exponential model param0.00.10.2-0.20.2-0.20.1-0.0-0.40.10.1-0.10.00.1-0.3-0.20.2-0.00.4-0.20.20.5
Extinction: sum of active levers before priming0.20.20.60.0-0.50.50.5-0.4-0.3-0.2-0.30.3-0.3-0.2-0.6-0.8-0.30.10.70.4-0.30.5
Active lever presses in extinction session 62.62.66.72.21.0-1.0-2.31.02.4-1.30.9-0.90.8-1.42.12.3-0.7-0.3-2.4-0.40.3-2.6
Bone: final force0.10.20.50.10.6-0.6-0.40.60.1-0.10.4-0.40.40.20.70.5-0.4-0.5-0.4-0.50.5-0.0
Bone: final moment0.20.40.80.30.9-0.9-0.50.80.3-0.30.6-0.60.6-0.10.80.6-0.6-0.8-0.5-0.80.8-0.2
Food consumed during 24 hour testing period2.32.87.62.11.2-1.2-1.81.42.5-1.41.2-1.21.2-1.92.21.9-1.0-1.1-2.1-0.60.7-2.8
Glucose0.10.10.30.4-0.20.2-0.2-0.10.5-0.30.3-0.30.2-0.50.10.0-0.30.1-0.30.3-0.3-0.4
Heart weight1.01.42.01.11.4-1.4-1.31.21.2-0.91.1-1.11.2-0.91.21.3-1.1-1.1-1.1-1.11.2-1.1
Delay discount hyperbolic model param0.10.10.3-0.5-0.00.00.3-0.2-0.60.4-0.20.2-0.20.4-0.4-0.30.50.20.50.0-0.00.6
Intermittent access intake day 1-15 change1.91.94.81.71.0-1.0-1.70.91.8-1.11.2-1.21.2-1.12.01.8-0.7-0.6-2.2-0.40.4-1.9
Intermittent access intake escalation2.42.45.61.91.1-1.1-1.91.12.1-1.31.4-1.41.4-1.32.21.9-1.0-0.8-2.4-0.50.5-2.1
Intermittent access intake escalation 20.70.71.31.00.9-0.9-1.00.80.9-0.70.7-0.70.7-0.71.11.0-0.6-0.7-1.1-0.60.7-0.9
Intermitt. access day 1 inactive lever presses0.50.60.8-0.6-0.80.80.9-0.8-0.80.7-0.80.8-0.80.7-0.9-0.90.60.70.80.6-0.70.7
Intermitt. access day 15 inactive lever presses0.10.10.40.1-0.50.50.1-0.50.00.3-0.40.4-0.40.3-0.0-0.10.40.5-0.30.6-0.7-0.2
Intermitt. access escalation Index0.10.10.2-0.20.4-0.4-0.20.50.00.10.1-0.10.10.10.30.40.1-0.3-0.0-0.40.4-0.1
Intermittent access day 1 total infusions0.60.71.10.90.9-0.9-0.60.90.7-0.90.9-0.90.9-0.90.60.6-1.0-1.1-0.4-1.01.0-0.5
Intermittent access day 15 total infusions2.12.34.31.91.2-1.2-1.81.22.0-1.41.4-1.41.4-1.42.01.8-1.1-1.0-2.1-0.80.8-2.0
Intermittent access terminal intake (last 3 days)1.41.62.41.61.2-1.2-1.41.11.4-1.11.3-1.31.3-1.11.51.4-1.1-1.1-1.5-1.01.0-1.3
Intermittent access total infusions0.60.71.11.00.8-0.8-0.80.80.9-0.90.8-0.80.8-0.90.90.8-0.9-0.8-0.8-0.80.8-0.8
Intermittent access day 1 locomotion0.00.00.10.2-0.10.1-0.1-0.10.20.1-0.10.1-0.20.10.20.20.20.2-0.30.1-0.2-0.3
Intermittent access day 15 total locomotion1.41.52.71.70.9-0.9-1.40.81.6-1.31.3-1.31.3-1.31.31.3-1.1-0.7-1.5-0.50.5-1.5
Intermittent access total locomotion0.50.61.11.00.6-0.6-0.70.60.8-0.91.0-1.00.9-0.90.70.6-0.9-0.6-0.7-0.50.5-0.6
Intermittent access standard deviation0.10.10.40.40.4-0.4-0.10.20.3-0.40.0-0.00.1-0.40.10.0-0.6-0.4-0.1-0.50.4-0.1
Left kidney weight1.02.96.31.21.8-1.8-0.62.00.6-1.92.0-2.01.9-2.10.20.1-2.5-2.40.3-2.32.30.1
Right kidney weight0.61.64.00.91.3-1.3-0.31.40.5-1.51.4-1.41.2-1.70.1-0.1-2.0-1.90.4-1.71.80.1
Cocaine induced anxiety2.32.73.3-1.7-1.81.81.7-1.5-1.71.7-1.71.7-1.81.7-1.6-1.61.61.51.51.4-1.41.5
Post-drug Anxiety0.50.50.8-0.8-0.80.80.8-0.7-0.70.8-0.90.9-0.80.8-0.6-0.60.80.60.60.6-0.60.5
Baseline Anxiety2.52.63.41.71.7-1.7-1.71.51.9-1.61.7-1.71.7-1.61.81.7-1.4-1.5-1.7-1.31.3-1.7
Tail length2.57.416.71.23.0-3.0-0.23.00.2-2.93.1-3.13.0-3.1-0.3-0.4-3.7-4.11.4-4.04.11.0
Length with tail0.93.27.90.71.6-1.60.41.7-0.2-1.91.9-1.91.8-2.0-0.6-0.9-2.8-2.81.4-2.52.61.2
Length without tail0.30.61.4-0.2-1.11.10.4-1.0-0.20.6-0.90.9-0.90.6-0.3-0.30.51.0-0.11.2-1.10.0
Times rat made contact with spout0.30.31.6-0.5-0.20.21.00.0-0.70.4-0.20.2-0.20.2-0.9-1.0-0.1-0.41.3-0.20.30.7
Lifetime Intake0.91.01.51.21.0-1.0-1.00.91.1-1.01.0-1.01.0-1.01.01.0-1.0-0.9-0.9-0.90.9-1.0
Liver weight, left0.30.51.8-0.6-0.40.41.2-0.2-0.8-0.20.0-0.00.10.2-1.0-1.4-0.6-0.61.3-0.20.31.0
Liver weight, right1.32.27.1-1.6-1.11.12.3-0.8-2.00.5-0.70.7-0.70.6-2.2-2.7-0.2-0.32.50.1-0.02.5
Locomotor activity0.91.42.61.31.4-1.4-1.11.21.3-0.91.2-1.21.2-1.60.91.0-1.3-1.3-0.7-1.21.3-1.0
Locomotor testing distance2.33.86.11.82.2-2.2-1.62.01.5-2.22.2-2.22.2-2.51.11.2-2.3-2.2-0.9-2.22.3-0.8
Locomotor testing rearing1.11.73.81.01.5-1.5-0.41.30.2-1.41.3-1.31.2-1.7-0.2-0.0-1.9-1.80.5-1.91.90.6
Locomotion in novel chamber0.81.02.21.00.7-0.7-1.40.91.5-1.00.8-0.80.8-0.91.31.3-0.5-0.4-1.4-0.40.4-1.5
Locomotion in novel chamber post-restriction2.93.57.92.31.4-1.4-2.61.42.7-1.61.4-1.41.5-1.72.42.6-0.9-0.7-2.7-0.70.6-2.8
Fecal boli incidents, locomotor time 10.80.81.71.10.6-0.6-1.10.61.1-0.81.1-1.10.9-0.71.21.1-0.5-0.3-1.3-0.30.3-1.2
Change in fecal boli incidents, locomotor task1.31.22.2-1.0-1.31.31.1-1.2-0.81.1-1.51.5-1.11.1-1.0-1.00.91.10.91.1-1.10.5
Time >=10cm from walls, locomotor time 11.61.63.31.61.0-1.0-1.71.11.7-1.10.9-0.91.3-0.91.61.8-0.6-0.5-1.8-0.60.6-1.8
Bouts of movement, locomotor time 10.10.10.40.6-0.10.1-0.2-0.10.5-0.60.4-0.40.1-0.50.20.1-0.4-0.0-0.30.3-0.3-0.4
Total resting periods, locomotor time 10.10.10.50.4-0.40.4-0.1-0.50.4-0.20.0-0.0-0.3-0.10.10.10.10.5-0.40.7-0.7-0.5
Rest time, locomotor task time 10.70.72.2-0.0-1.21.20.4-1.10.30.3-0.90.9-1.30.3-0.2-0.30.51.1-0.31.4-1.5-0.6
Distance moved, locomotor task time 11.11.23.10.21.4-1.4-0.31.4-0.3-0.91.3-1.31.6-0.80.10.1-1.0-1.60.4-1.81.80.8
Vertical activity count, locomotor time 11.41.53.80.31.7-1.7-0.81.70.1-0.81.3-1.31.6-0.80.60.7-0.9-1.6-0.2-1.91.90.4
Time >=10cm from walls, locomotor time 21.01.12.21.50.8-0.8-1.00.81.1-1.51.1-1.11.4-1.30.70.7-1.3-0.8-0.8-0.60.7-0.9
Bouts of movement, locomotor time 20.60.71.51.20.6-0.6-0.60.50.9-1.21.2-1.20.7-1.10.50.4-1.1-0.7-0.4-0.40.4-0.7
Total resting periods, locomotor time 20.30.41.01.00.3-0.3-0.40.20.7-0.91.0-1.00.5-0.80.30.2-0.7-0.4-0.4-0.10.1-0.6
Rest time, locomotor task time 22.02.32.9-1.7-1.71.71.6-1.7-1.41.7-1.31.3-1.61.7-1.3-1.41.51.51.11.5-1.61.1
Distance moved, locomotor task time 22.83.25.41.72.0-2.0-1.62.01.4-2.31.9-1.92.0-2.21.21.3-2.1-2.0-0.9-2.01.9-0.8
Vertical activity count, locomotor time 22.02.14.41.01.8-1.8-1.01.90.6-1.51.5-1.51.7-1.50.60.8-1.7-1.9-0.2-2.12.10.0
Light reinforcement 11.52.84.1-2.0-1.71.72.0-1.7-2.01.4-1.61.6-1.51.7-1.7-2.01.31.21.61.4-1.51.9
Light reinforcement 20.10.20.6-0.1-0.50.5-0.0-0.30.3-0.1-0.20.2-0.20.20.40.00.20.4-0.60.7-0.7-0.4
Bone: marrow area1.22.55.21.12.0-2.0-0.81.90.7-1.71.6-1.61.6-1.70.60.5-2.0-2.30.0-2.22.3-0.0
Bone: maximum diameter2.64.87.11.72.7-2.7-1.82.61.5-2.42.5-2.52.4-2.11.61.5-2.4-2.6-1.1-2.62.6-0.9
Bone: maximum force0.30.51.10.31.0-1.0-0.71.00.4-0.30.4-0.40.5-0.01.10.9-0.4-0.8-0.7-0.80.8-0.4
Bone: maximum moment0.40.71.60.51.3-1.3-0.81.20.5-0.50.6-0.60.7-0.21.11.0-0.6-1.0-0.7-1.01.0-0.4
Mean time between licks in bursts4.66.411.12.62.7-2.7-1.72.62.0-3.03.0-3.02.7-3.31.61.2-3.3-3.2-1.1-2.72.7-1.2
Mean num. licks in bursts3.44.14.92.22.2-2.2-2.22.12.2-1.91.9-1.92.1-2.22.02.1-1.5-1.8-1.8-1.91.9-2.1
Cd content in liver0.80.92.7-1.3-0.50.51.2-0.1-1.50.8-0.70.7-0.80.9-1.3-1.20.40.11.5-0.00.11.6
Co content in liver0.81.02.10.61.3-1.3-0.31.10.3-1.01.0-1.00.9-1.2-0.10.1-1.4-1.40.4-1.51.40.1
Cu content in liver0.60.71.60.80.5-0.5-0.20.80.5-1.21.1-1.10.9-1.3-0.1-0.2-1.3-1.00.2-0.91.00.1
Fe content in liver0.00.00.2-0.2-0.00.00.10.1-0.2-0.20.4-0.40.10.1-0.2-0.2-0.2-0.10.2-0.10.10.4
K content in liver0.20.20.4-0.6-0.30.30.6-0.3-0.50.6-0.50.5-0.40.4-0.5-0.50.50.10.6-0.0-0.00.5
Mg content in liver0.10.20.30.50.4-0.4-0.40.40.4-0.40.4-0.40.4-0.40.30.4-0.3-0.3-0.3-0.50.4-0.3
Mn content in liver1.82.03.6-1.0-1.61.60.9-1.9-0.81.6-1.61.6-1.71.5-0.6-0.71.71.90.21.9-1.90.3
Na content in liver0.50.62.01.00.3-0.3-1.0-0.01.1-0.30.6-0.60.5-0.41.21.1-0.10.1-1.40.1-0.2-1.3
Rb content in liver0.81.02.30.81.3-1.3-0.71.30.7-0.90.7-0.71.1-1.00.40.7-0.9-1.3-0.1-1.51.5-0.3
Se content in liver4.85.98.8-2.3-3.03.02.3-2.8-2.02.5-2.42.4-2.82.5-2.0-2.12.32.61.52.7-2.71.4
Sr content in liver0.10.10.3-0.2-0.20.2-0.1-0.30.10.1-0.20.2-0.20.10.00.10.60.4-0.20.3-0.4-0.3
Zn content in liver5.25.77.82.52.5-2.5-2.52.82.2-2.52.8-2.82.6-2.62.22.2-2.3-2.2-2.0-2.22.2-1.6
Bone: minimum diameter0.81.53.90.11.3-1.30.21.3-0.4-1.11.2-1.21.2-1.0-0.4-0.5-1.6-1.91.0-1.92.01.0
Time in familiar zone, hab. session 10.10.10.2-0.4-0.30.30.4-0.2-0.40.3-0.30.3-0.20.4-0.2-0.30.3-0.10.30.1-0.10.2
Time in novel zone, hab. session 10.10.10.5-0.20.0-0.00.3-0.1-0.4-0.10.1-0.10.1-0.1-0.5-0.4-0.3-0.10.5-0.20.20.7
Total zone transitions, hab. session 10.20.31.20.60.1-0.1-0.80.10.70.10.3-0.30.20.11.01.00.10.3-1.10.3-0.3-0.9
Total locomotion distance, hab. session 10.91.34.2-1.4-0.60.61.5-0.5-1.80.8-0.60.6-0.90.7-1.6-1.70.30.01.8-0.00.02.1
Locomotion velocity, hab. session 10.60.82.9-1.1-0.40.41.1-0.2-1.40.7-0.40.4-0.70.5-1.3-1.20.3-0.01.4-0.10.11.7
Time in familiar zone, hab. session 21.21.32.60.61.6-1.6-0.81.50.5-0.81.0-1.01.4-0.90.90.8-0.7-1.5-0.4-1.61.6-0.4
Time in novel zone, hab. session 20.50.51.4-0.1-1.11.10.4-1.1-0.1-0.1-0.40.4-0.80.1-0.6-0.60.21.00.01.2-1.20.1
Total zone transitions, hab. session 21.01.44.01.40.8-0.8-1.71.01.5-0.90.8-0.80.5-0.71.81.8-0.6-0.2-2.0-0.20.2-1.5
Total locomotion distance, hab. session 20.30.42.2-0.90.1-0.10.70.3-1.10.0-0.20.2-0.50.2-0.7-0.9-0.1-0.50.9-0.40.41.5
Locomotion velocity, hab. session 20.40.52.5-0.9-0.00.00.80.2-1.20.1-0.30.3-0.60.2-0.9-1.1-0.1-0.51.1-0.40.41.6
Novel to familiar place preference ratio0.10.10.30.5-0.10.1-0.40.00.6-0.50.3-0.30.1-0.40.40.3-0.30.1-0.60.2-0.2-0.5
Novelty place preference0.10.10.20.5-0.30.3-0.3-0.10.5-0.40.1-0.1-0.0-0.40.20.1-0.30.1-0.40.3-0.3-0.4
Time in novel zone, NPP test0.20.20.40.7-0.10.1-0.50.10.6-0.60.4-0.40.2-0.60.40.3-0.4-0.0-0.60.2-0.2-0.5
Total zone transitions, NPP test0.20.31.20.7-0.10.1-0.6-0.10.7-0.0-0.10.1-0.3-0.00.80.7-0.10.4-1.10.6-0.6-0.9
Total locomotion distance, NPP test1.11.54.0-1.4-1.11.11.5-0.9-1.70.6-1.01.0-1.40.8-1.5-1.80.40.51.40.8-0.82.0
Locomotion velocity, NPP test1.52.25.0-1.6-1.41.41.8-1.3-1.90.8-1.31.3-1.71.0-1.9-2.10.60.81.61.0-1.02.2
Intraocular pressure0.40.61.81.10.4-0.4-1.20.50.9-0.40.8-0.80.7-0.41.11.2-0.10.1-1.3-0.10.1-1.0
Delta distance traveled before/after self-admin0.10.10.50.2-0.30.3-0.4-0.20.50.1-0.10.1-0.00.10.40.50.30.5-0.70.5-0.6-0.7
Delta ambulatory time before/after self-admin0.30.30.90.2-0.40.4-0.5-0.30.60.3-0.30.3-0.20.30.60.60.60.8-1.00.8-0.9-0.9
Parametrial fat weight0.30.62.7-0.8-0.10.11.1-0.2-1.20.20.1-0.10.00.4-1.1-1.2-0.6-0.51.4-0.50.51.6
Pavlov. Cond. lever latency0.91.11.7-1.2-1.11.10.8-1.3-1.10.9-1.11.1-1.01.1-0.8-0.81.21.20.51.2-1.20.9
Pavlov. Cond. magazine entry latency2.63.34.91.72.1-2.1-1.72.21.4-2.02.0-2.01.9-1.81.41.4-1.9-2.1-1.0-2.12.1-0.9
Pavlov. Cond. change in total contacts0.60.61.21.00.8-0.8-0.70.90.8-1.10.8-0.80.6-1.00.60.6-1.0-0.8-0.5-0.80.7-0.6
Pavlov. Cond. index score2.32.94.41.61.9-1.9-1.42.11.3-1.81.9-1.91.7-1.91.11.2-1.9-2.0-0.7-2.12.0-0.8
Pavlov. Cond. latency score2.22.84.41.61.9-1.9-1.42.11.3-1.71.8-1.81.7-1.81.21.2-1.8-2.0-0.8-2.02.0-0.9
Pavlov. Cond. lever contacts0.70.81.60.91.0-1.0-0.51.20.6-0.80.9-0.90.7-1.20.40.4-1.2-1.2-0.0-1.21.2-0.4
Pavlov. Cond. magazine entry number3.03.85.4-1.9-2.22.21.8-2.3-1.62.1-2.32.3-2.12.0-1.5-1.62.02.01.22.1-2.11.1
Pavlov. Cond. intertrial magazine entries2.22.74.4-1.4-2.12.11.7-1.9-1.41.4-1.71.7-1.71.2-1.8-1.81.21.71.41.7-1.71.1
Pavlov. Cond. lever-magazine prob. diff.1.82.23.51.41.6-1.6-1.21.81.1-1.51.6-1.61.5-1.61.01.0-1.7-1.8-0.6-1.91.8-0.8
Pavlov. Cond. response bias0.70.81.50.81.0-1.0-0.51.20.6-0.81.0-1.00.8-1.10.40.4-1.1-1.2-0.1-1.21.2-0.3
Pavlov. Cond. lever latency20.227.232.1-5.7-5.55.55.6-5.6-5.55.6-5.25.2-5.25.3-5.5-5.24.94.74.94.5-4.44.6
Pavlov. Cond. magazine entry latency5.56.39.52.62.7-2.7-3.12.82.8-2.42.3-2.32.4-2.13.03.1-1.8-1.9-2.8-2.01.9-2.5
Pavlov. Cond. change in total contacts13.518.623.54.74.5-4.5-4.84.54.6-4.84.4-4.44.3-4.54.54.4-4.0-3.6-4.3-3.53.4-3.8
Pavlov. Cond. index score15.820.325.44.94.8-4.8-5.04.84.8-4.84.5-4.54.5-4.54.84.7-4.1-3.9-4.4-3.93.8-4.0
Pavlov. Cond. latency score14.518.023.34.64.5-4.5-4.84.54.6-4.54.2-4.24.1-4.14.64.6-3.8-3.6-4.3-3.53.5-3.8
Pavlov. Cond. lever contacts21.329.234.15.85.7-5.7-5.85.85.6-5.85.5-5.55.4-5.55.65.4-5.1-4.9-5.1-4.74.6-4.6
Pavlov. Cond. magazine entry number7.28.813.1-3.2-3.13.13.6-3.2-3.23.1-2.92.9-2.82.9-3.3-3.42.42.23.22.3-2.32.7
Pavlov. Cond. intertrial magazine entries0.40.51.2-0.20.1-0.10.80.1-0.6-0.50.7-0.70.7-0.5-0.8-1.1-0.9-1.01.1-0.80.80.9
Pavlov. Cond. lever-magazine prob. diff.14.818.923.24.74.5-4.5-4.84.64.6-4.74.4-4.44.3-4.44.64.5-4.0-3.8-4.2-3.73.6-3.8
Pavlov. Cond. response bias21.228.834.55.75.7-5.7-5.95.85.6-5.75.4-5.45.4-5.45.65.5-4.9-4.8-5.1-4.74.7-4.6
Time in closed arm before self-admin0.91.03.41.10.3-0.3-1.50.31.5-0.50.6-0.60.5-0.51.51.60.00.3-1.90.3-0.4-1.8
Time in closed arm after self-admin0.60.71.8-0.3-1.01.00.4-1.1-0.10.9-0.80.8-0.70.9-0.0-0.11.11.1-0.21.3-1.3-0.4
Time in open arm before self-admin2.72.94.0-2.0-1.71.72.0-1.7-2.01.8-1.71.7-1.71.7-1.9-1.91.41.41.81.3-1.21.8
Time in open arm after self-admin0.70.82.80.21.2-1.2-0.11.2-0.2-0.60.3-0.30.5-0.7-0.10.0-0.9-1.30.5-1.61.70.6
Bone: periosteal estimation1.53.15.91.22.2-2.2-1.02.10.7-2.01.9-1.91.9-1.80.70.7-2.3-2.4-0.2-2.42.40.0
Bone: periosteal perimeter1.93.15.51.42.2-2.2-1.22.01.2-1.91.9-1.91.9-1.91.21.1-1.9-2.3-0.6-2.32.3-0.7
Bone: post-yield work0.60.81.80.51.2-1.2-0.91.30.6-0.40.6-0.60.8-0.31.11.1-0.3-1.0-0.7-1.11.1-0.7
Progressive ratio test 1 active lever presses0.20.30.6-0.3-0.70.70.4-0.8-0.30.5-0.40.4-0.50.5-0.3-0.30.50.60.10.7-0.70.1
Progressive ratio test 1 breakpoint0.20.20.4-0.3-0.60.60.4-0.6-0.30.6-0.40.4-0.50.6-0.2-0.30.50.50.10.5-0.60.2
Progressive ratio test 1 inactive lever presses0.10.10.10.20.3-0.3-0.20.40.2-0.10.4-0.40.4-0.10.30.3-0.2-0.3-0.1-0.40.3-0.1
Progressive ratio test 2 active lever presses1.61.72.61.51.2-1.2-1.11.21.2-1.61.6-1.61.6-1.60.90.9-1.6-1.3-0.8-1.21.3-0.8
Progressive ratio test 2 breakpoint1.41.62.51.51.3-1.3-1.11.21.0-1.41.6-1.61.6-1.40.90.9-1.5-1.3-0.8-1.31.3-0.6
Progressive ratio test 2 inactive lever presses0.60.71.21.10.8-0.8-0.80.80.8-1.01.1-1.11.1-1.00.50.6-1.0-0.8-0.6-0.80.8-0.5
Incentive Sensitization - Responses3.23.24.71.91.9-1.9-1.61.91.5-2.02.2-2.22.2-2.01.31.3-2.0-1.9-1.1-1.92.0-1.0
Incentive Sensitization - Breakpoint3.03.14.51.81.8-1.8-1.61.81.5-1.92.1-2.12.1-1.91.41.4-1.9-1.8-1.2-1.81.8-1.1
Sum of active levers in priming session hrs 5-60.10.10.50.2-0.50.50.2-0.30.0-0.1-0.60.6-0.7-0.2-0.3-0.3-0.20.20.20.3-0.30.0
Progressive ratio0.10.10.60.0-0.00.0-0.50.10.30.2-0.10.1-0.10.10.60.50.30.3-0.70.2-0.2-0.4
Food seeking constrained by brief footshock1.82.33.91.61.5-1.5-1.21.41.4-1.91.6-1.61.8-1.91.11.0-2.0-1.7-0.8-1.41.4-1.0
Seeking ratio, punishment vs. effort1.11.43.11.11.2-1.2-0.51.10.7-1.61.3-1.31.5-1.40.30.2-1.8-1.60.1-1.41.4-0.3
Retroperitoneal fat weight2.89.329.8-3.7-1.51.54.3-1.3-4.61.3-1.71.7-1.51.4-4.8-4.90.0-0.45.3-0.40.65.5
Reaction time number correct0.30.41.40.1-0.40.4-0.5-0.40.70.3-0.40.4-0.40.30.80.80.90.8-1.00.8-0.8-1.2
Reaction time mean minus median1.52.03.41.61.6-1.6-1.11.41.2-1.51.7-1.71.6-1.60.90.9-1.8-1.7-0.6-1.51.6-0.8
Reaction time mean minus median AUC1.72.13.21.81.5-1.5-1.41.31.5-1.51.6-1.61.6-1.61.41.2-1.6-1.4-1.2-1.21.3-1.3
Reaction time num false alarms2.33.15.5-2.3-1.41.42.0-1.4-2.31.6-2.02.0-1.81.8-1.9-2.01.41.11.91.0-1.02.3
Reaction time num false alarms AUC1.62.13.1-1.8-1.31.31.6-1.4-1.71.4-1.71.7-1.61.4-1.4-1.61.31.11.31.1-1.11.6
Reaction time trials correct on left0.30.41.40.1-0.40.4-0.5-0.40.70.3-0.40.4-0.40.30.80.80.90.8-1.00.8-0.8-1.2
Reaction time trials on left0.30.51.50.1-0.40.4-0.6-0.40.70.2-0.40.4-0.40.30.80.80.90.8-1.10.8-0.8-1.2
Reaction time mean0.10.10.50.1-0.30.30.6-0.2-0.3-0.10.1-0.10.0-0.0-0.5-0.7-0.6-0.30.6-0.10.10.5
Reaction time mean AUC0.20.30.9-0.1-0.70.70.9-0.7-0.50.2-0.30.3-0.40.3-0.7-1.0-0.30.20.70.4-0.40.6
Median of all reaction times0.30.41.0-0.3-0.90.91.0-0.7-0.60.4-0.50.5-0.60.5-0.8-1.00.00.30.80.5-0.50.7
Reaction time omissions0.00.10.30.2-0.10.10.2-0.1-0.1-0.50.3-0.30.1-0.1-0.2-0.4-0.6-0.20.2-0.00.10.3
Reaction time false alarm rate1.52.14.6-1.8-1.11.11.8-1.2-2.01.2-1.51.5-1.41.4-1.7-1.80.80.71.70.7-0.72.1
Reaction time premature initiation rate2.53.48.30.92.4-2.4-0.82.20.2-1.71.9-1.92.1-1.60.30.5-2.2-2.70.3-2.92.90.6
Reaction time premature initiations1.72.35.01.02.0-2.0-1.11.80.7-1.51.6-1.61.8-1.40.81.0-1.6-2.0-0.4-2.22.2-0.2
Std. dev. reaction times0.81.22.80.91.1-1.1-0.31.10.4-1.21.3-1.31.3-1.30.10.0-1.7-1.50.3-1.41.50.1
Reaction time trials completed0.30.51.50.1-0.40.4-0.6-0.40.70.2-0.40.4-0.40.30.80.80.90.8-1.10.8-0.8-1.2
Reaction time trials AUC0.20.31.30.2-0.30.3-0.5-0.30.70.0-0.20.2-0.20.10.70.70.70.6-1.00.7-0.7-1.1
Run reversals in cocaine runway, females1.41.44.5-0.90.6-0.61.30.6-1.5-0.10.3-0.30.4-0.1-1.4-1.5-1.0-1.42.0-1.51.52.1
Run reversals in cocaine runway, males0.10.10.40.6-0.00.0-0.1-0.10.40.10.4-0.4-0.00.10.40.2-0.1-0.0-0.20.2-0.2-0.5
Latency to leave start box in cocaine runway2.12.33.9-1.3-1.61.61.5-1.5-1.41.4-2.02.0-2.01.4-1.3-1.41.31.31.31.4-1.41.2
Latency to leave start box in cocaine runway, F1.41.52.1-1.4-1.21.21.4-1.1-1.41.0-1.21.2-1.51.1-1.3-1.50.90.81.30.9-0.91.4
Latency to leave start box in cocaine runway, M0.50.51.2-0.3-0.70.70.2-0.6-0.20.9-1.11.1-0.90.9-0.00.01.10.9-0.10.8-0.8-0.2
Std. dev. time between licks in bursts1.11.32.90.81.2-1.2-0.31.30.5-1.31.3-1.31.0-1.60.20.0-1.7-1.70.2-1.51.50.0
Total sessions with >9 infusions2.12.33.61.61.5-1.5-1.91.51.7-1.31.5-1.51.5-1.31.81.9-1.0-1.1-1.7-1.21.1-1.7
Short access day 1 total inactive lever presses0.10.20.60.1-0.70.70.5-0.70.10.0-0.10.1-0.20.0-0.4-0.5-0.00.40.20.5-0.5-0.1
Short access day 10 total inactive lever presses0.20.20.4-0.4-0.40.40.3-0.5-0.30.5-0.60.6-0.60.5-0.3-0.20.50.50.20.4-0.40.2
Short access day 1 total infusions2.42.63.51.91.6-1.6-1.61.51.8-1.71.9-1.91.8-1.71.51.5-1.6-1.5-1.2-1.51.4-1.5
Short access day 10 total infusions0.60.61.00.80.9-0.9-0.60.90.6-0.90.7-0.70.8-0.90.50.6-0.9-0.9-0.3-1.01.0-0.4
Short access total infusions0.60.71.00.80.9-0.9-0.70.90.7-0.80.9-0.90.9-0.80.80.8-0.8-0.9-0.5-1.00.9-0.6
Short access day 1 locomotion2.02.15.61.80.9-0.9-2.10.92.1-1.01.1-1.11.0-1.02.12.2-0.5-0.3-2.4-0.30.2-2.2
Short access day 10 total locomotion0.20.20.40.60.4-0.4-0.50.50.4-0.60.6-0.60.5-0.60.40.4-0.6-0.4-0.4-0.50.4-0.2
Short access total locomotion0.10.10.40.40.2-0.2-0.50.20.4-0.10.1-0.10.1-0.10.50.60.00.0-0.7-0.1-0.0-0.5
One hour access (0.3 mA shock)1.82.13.01.71.5-1.5-1.51.61.3-1.61.5-1.51.6-1.61.11.3-1.6-1.4-1.0-1.51.5-1.0
Compulsive drug intake0.00.00.1-0.0-0.10.1-0.3-0.10.1-0.10.0-0.0-0.1-0.10.10.20.10.4-0.20.4-0.3-0.1
One hour access (shock baseline)1.41.63.11.71.2-1.2-1.21.21.3-1.31.2-1.21.3-1.31.21.2-1.3-1.2-1.2-1.21.1-1.1
Social response proportion0.50.61.1-0.6-0.70.71.0-0.6-0.80.6-1.01.0-0.80.5-0.9-1.00.40.30.90.5-0.50.8
Social responses0.71.02.8-1.1-0.40.41.4-0.4-1.50.6-0.90.9-0.70.6-1.4-1.50.1-0.11.6-0.10.21.7
Social time3.64.86.8-2.0-2.42.42.0-2.6-1.81.9-2.52.5-2.52.1-1.9-1.92.32.41.32.5-2.51.5
Soleus weight0.41.23.8-0.80.7-0.71.10.6-1.3-0.10.0-0.00.2-0.2-1.2-1.3-0.7-1.41.9-1.51.51.9
Bone: stiffness0.00.10.2-0.10.3-0.30.10.4-0.20.2-0.00.0-0.00.50.50.1-0.2-0.5-0.2-0.20.20.2
Tibialis anterior weight0.10.51.30.30.9-0.9-0.20.9-0.0-0.80.7-0.70.7-0.50.20.1-0.8-1.10.2-1.11.10.3
Time to tail flick, vehicle, before self-admin0.40.41.2-1.1-0.10.10.7-0.1-1.00.7-0.40.4-0.30.6-0.8-0.60.50.11.0-0.20.21.1
Time to tail flick, vehicle, after self-admin1.81.93.11.41.5-1.5-1.71.41.6-1.11.4-1.41.3-1.11.71.8-0.8-1.0-1.7-1.11.0-1.6
Time to tail flick, test, before self-admin0.20.20.60.10.5-0.5-0.10.60.0-0.40.4-0.40.4-0.40.00.0-0.6-0.70.1-0.80.70.2
Time to tail flick, test, after self-admin0.40.41.20.50.6-0.60.00.40.2-0.90.8-0.80.7-0.9-0.3-0.3-1.1-0.80.3-0.70.70.1
Delta time to tail flick, vehicle, before/after SA2.72.76.02.01.2-1.2-2.11.12.3-1.31.5-1.51.4-1.32.22.2-0.8-0.6-2.4-0.50.5-2.4
Delta time to tail flick, test, before/after SA0.20.20.60.0-0.50.50.3-0.7-0.00.2-0.40.4-0.50.2-0.3-0.30.30.60.10.7-0.7-0.1
Tibia length1.13.06.31.91.8-1.8-2.51.62.1-1.51.4-1.41.4-1.42.22.5-0.8-0.6-2.4-0.90.9-2.1
Ambulatory time before self-admin0.60.61.0-0.7-1.01.00.7-0.9-0.60.8-0.80.8-0.90.8-0.5-0.60.80.80.40.9-0.80.3
Ambulatory time after self-admin1.71.84.2-0.8-1.91.90.7-1.8-0.31.3-1.31.3-1.31.3-0.5-0.51.52.0-0.12.0-2.0-0.2
Bone: tissue strength0.70.61.8-0.3-0.50.5-0.3-0.4-0.11.0-0.80.8-0.91.10.50.71.31.2-0.81.0-1.0-0.4
Total heroin consumption0.10.10.20.40.1-0.1-0.40.30.3-0.1-0.20.2-0.4-0.20.40.4-0.1-0.1-0.4-0.10.1-0.3
Bone: trabecular number0.81.23.5-1.5-0.80.81.0-0.9-1.21.6-1.31.3-1.01.9-0.8-0.61.51.00.90.6-0.60.7
Bone: trabecular spacing0.91.22.51.50.6-0.6-1.30.71.6-1.41.3-1.30.8-1.51.11.1-0.8-0.5-1.3-0.30.3-1.5
Bone: trabecular thickness0.30.31.1-0.70.1-0.10.8-0.1-0.90.3-0.40.4-0.10.4-0.8-0.8-0.1-0.31.1-0.40.41.0
Bone: trabecular tissue density0.60.82.5-1.0-0.60.61.4-0.9-1.30.4-0.50.5-0.70.3-1.2-1.60.0-0.11.30.3-0.31.6
Water consumed over 24 hours1.21.52.1-1.3-1.31.31.4-1.1-1.11.4-1.41.4-1.31.2-1.1-1.21.11.01.21.1-1.00.8
Number of responses in last shaping day0.40.41.2-0.20.7-0.70.20.8-0.6-0.20.3-0.30.4-0.2-0.5-0.3-0.5-0.80.8-1.11.10.9