Hub : Genes

Thap12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Thap12 0.5 0.21 2.0e-04 0.03 0.06 0.05 0.05 7.7e-02 1.2e-02 2.3e-02 2.5e-02
2 IC gene expression Thap12 0.25 0.12 1.2e-08 0.13 0.2 0.2 0.08 5.0e-06 7.8e-09 9.5e-09 2.7e-04
3 pVTA isoform ratio NM_001191630.2 0.2 0.09 2.6e-15 0.2 0.19 0.19 0.2 3.1e-16 5.6e-15 2.2e-15 1.2e-15
4 pVTA isoform ratio XM_039113219.1 0.2 0.09 1.3e-15 0.2 0.19 0.2 0.2 2.2e-16 2.2e-15 1.5e-15 6.8e-16
5 PL isoform ratio XM_039113219.1 0.1 0.06 9.2e-09 0.07 0.08 0.07 0.08 1.7e-08 8.8e-09 2.9e-08 1.1e-08
6 Adipose mRNA stability Thap12 0.07 0.04 7.3e-06 0.04 0.04 0.04 0.04 7.7e-05 1.3e-05 3.3e-05 2.7e-05
7 Brain mRNA stability Thap12 0.07 0.05 1.0e-05 0.05 0.05 0.04 0.05 1.3e-05 2.5e-05 2.2e-04 3.1e-05
8 PL isoform ratio NM_001191630.2 0.1 0.06 1.9e-08 0.07 0.07 0.07 0.07 3.0e-08 2.2e-08 8.3e-08 2.4e-08
9 Brain gene expression Thap12 0.27 0.11 0.0e+00 0.19 0.2 0.2 0.2 9.1e-18 1.5e-18 2.4e-18 2.6e-18
10 OFC gene expression Thap12 0.26 0.15 8.7e-04 0.1 0.1 0.1 0.1 2.5e-03 2.3e-03 2.8e-03 2.7e-03
11 NAcc mRNA stability Thap12 0.02 0.02 3.1e-03 0.02 0.01 0.01 0.01 7.9e-04 3.9e-03 3.5e-03 5.1e-03
12 NAcc isoform ratio XM_039113219.1 0.07 0.04 4.3e-08 0.05 0.05 0.05 0.05 8.1e-08 1.4e-08 2.5e-08 6.4e-08
13 BLA gene expression Thap12 0.18 0.12 4.1e-05 0.05 0.08 0.07 0.05 1.2e-03 3.1e-05 1.8e-04 1.0e-03
14 Adipose gene expression Thap12 0.09 0.07 1.8e-05 0.04 0.04 0.04 0.04 9.0e-06 2.3e-05 1.5e-05 1.4e-05
15 NAcc isoform ratio NM_001191630.2 0.06 0.04 3.6e-07 0.04 0.04 0.04 0.04 3.9e-07 1.8e-07 1.7e-07 4.1e-07
16 pVTA gene expression Thap12 0.07 0.05 7.7e-05 0.05 0.06 0.05 0.05 1.3e-04 3.0e-05 7.5e-05 4.2e-05
17 BLA isoform ratio XM_039113219.1 0.12 0.08 3.6e-05 0.05 0.08 0.08 0.07 8.3e-04 7.1e-05 6.1e-05 1.1e-04
18 BLA isoform ratio NM_001191630.2 0.13 0.08 3.0e-05 0.06 0.08 0.08 0.08 6.8e-04 4.6e-05 5.2e-05 7.5e-05
19 NAcc gene expression Thap12 0.09 0.05 1.3e-13 0.09 0.1 0.1 0.1 4.2e-14 1.6e-14 1.8e-14 1.5e-14
20 PL gene expression Thap12 0.11 0.06 1.0e-10 0.09 0.1 0.11 0.09 7.2e-10 8.8e-11 1.2e-11 4.9e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.10.10.6-0.2-0.1-0.20.20.20.3-0.0-0.2-0.0-0.30.1-0.0-0.1-0.80.4-0.50.3-0.3-0.3-0.3
Area under the delay curve0.10.10.20.30.4-0.00.00.1-0.3-0.1-0.10.40.4-0.20.20.30.2-0.20.4-0.10.00.30.5
BMI with tail0.51.68.0-1.0-0.9-0.20.20.21.0-0.6-0.3-1.7-1.5-0.20.6-1.60.5-1.0-1.61.5-1.3-2.2-2.8
BMI without tail0.92.78.8-0.6-0.3-1.11.11.10.8-1.5-1.3-1.5-1.4-1.11.5-1.51.3-1.8-1.72.7-2.4-2.5-3.0
Body weight0.62.48.6-0.7-0.4-0.90.90.90.9-1.3-1.1-1.5-1.4-0.91.4-1.61.1-1.9-1.72.4-2.2-2.4-2.9
Weight adjusted by age0.20.41.20.00.1-0.50.50.5-0.0-0.7-0.6-0.3-0.2-0.70.7-0.20.7-0.8-0.21.0-0.9-0.4-1.1
Bone surface1.62.95.01.61.8-2.22.22.2-1.3-2.0-2.21.51.2-1.72.01.31.2-1.60.82.2-2.10.80.1
Bone volume0.71.33.00.80.9-1.61.61.5-0.6-1.3-1.50.60.4-1.21.40.50.7-1.10.11.7-1.7-0.0-0.7
Breakpoint value in progressive ratio session1.01.22.2-0.9-1.11.3-1.3-1.40.71.21.4-0.7-0.61.4-1.4-0.5-1.11.3-0.3-1.41.5-0.30.4
Number of licking bursts2.84.56.5-2.5-2.42.2-2.2-2.12.52.22.0-2.4-2.51.9-1.8-2.5-2.21.7-2.4-1.51.4-2.0-1.5
Context. condit. distance diff. score2.12.64.51.81.6-1.71.71.6-2.1-2.0-1.61.81.9-1.51.22.11.1-0.91.91.4-1.11.40.4
Locomotion velocity, session 10.70.82.6-0.4-0.51.2-1.2-1.20.31.31.2-0.2-0.00.6-1.1-0.2-0.30.80.2-1.61.50.30.6
Locomotion distance, session 10.40.51.70.80.6-0.00.0-0.0-1.0-0.20.10.81.1-0.20.00.90.8-0.41.3-0.40.51.21.3
Locomotion velocity, session 20.10.10.40.10.10.2-0.2-0.10.10.30.1-0.10.1-0.20.1-0.20.7-0.40.1-0.30.20.00.5
Locomotion distance, session 20.10.20.70.40.3-0.10.10.1-0.5-0.2-0.10.30.5-0.40.20.30.8-0.50.60.00.00.50.7
Locomotion velocity, session 30.10.10.70.40.1-0.20.2-0.0-0.7-0.40.00.30.6-0.3-0.20.70.4-0.00.90.10.20.30.0
Locomotion distance, session 30.50.51.90.80.5-0.30.30.1-1.1-0.4-0.00.81.1-0.2-0.11.10.6-0.11.4-0.20.41.00.8
Stereotopy head waving bouts, day 30.30.41.0-0.8-0.60.6-0.6-0.40.90.50.4-0.7-0.90.6-0.2-0.9-0.30.3-1.0-0.30.1-0.9-0.4
Stereotopy head waving duration, day 30.30.30.50.60.7-0.50.50.6-0.6-0.5-0.60.70.6-0.70.50.70.6-0.40.60.4-0.40.50.5
Locomotion velocity, session 70.40.40.8-0.6-0.80.6-0.6-0.80.40.40.8-0.6-0.50.5-0.9-0.3-0.80.7-0.3-0.50.7-0.6-0.7
Locomotion distance, session 70.10.10.3-0.4-0.50.2-0.2-0.30.30.10.3-0.6-0.40.1-0.3-0.4-0.1-0.0-0.30.00.1-0.5-0.6
Stereotopy head waving bouts, day 71.51.73.81.61.5-1.01.01.1-1.6-1.1-1.01.81.7-0.80.91.81.0-0.61.70.4-0.41.61.9
Stereotopy head waving duration, day 72.12.63.71.91.9-1.61.61.6-1.8-1.6-1.61.91.8-1.51.51.91.5-1.21.71.1-1.11.61.5
Locomotion velocity, session 81.82.23.61.71.8-1.51.51.7-1.6-1.5-1.61.91.6-1.51.41.81.0-1.01.41.1-1.11.40.6
Locomotion distance, session 81.42.03.41.71.5-1.31.31.3-1.9-1.5-1.21.61.8-1.31.11.81.5-1.11.80.9-0.81.41.0
Degree of sensitization distance0.50.61.5-0.5-0.2-0.30.30.40.9-0.1-0.4-0.8-1.0-0.30.6-1.1-0.0-0.6-1.20.9-1.0-1.1-1.2
Degree of sensitization stereotypy3.53.86.62.42.3-1.61.61.7-2.4-1.7-1.62.62.5-1.41.42.51.5-1.22.40.7-0.82.52.5
Conditioned locomotion0.10.10.4-0.1-0.20.3-0.3-0.5-0.00.40.5-0.00.10.5-0.60.1-0.30.60.2-0.50.60.30.4
Cocaine response after cond. corrected1.11.32.3-1.3-1.21.2-1.2-1.31.41.41.2-1.3-1.30.9-0.9-1.5-0.90.6-1.2-1.10.9-1.1-0.8
Cocaine response after cond. not corrected0.30.41.0-0.5-0.50.8-0.8-0.80.60.90.8-0.5-0.40.4-0.6-0.6-0.50.3-0.4-1.00.8-0.20.0
Cocaine response before conditioning1.11.32.81.41.4-0.70.70.9-1.5-0.9-0.81.71.6-0.70.71.70.7-0.51.50.2-0.21.61.5
Saline control response1.72.33.41.61.7-1.51.51.6-1.4-1.6-1.61.41.4-1.71.71.21.7-1.81.21.3-1.41.31.2
Bone: connectivity density0.20.40.70.60.7-0.70.70.8-0.5-0.7-0.80.90.5-0.30.50.9-0.40.10.30.6-0.60.50.3
Bone: cortical apparent density1.01.42.3-1.3-1.11.3-1.3-1.01.51.31.0-1.2-1.41.2-0.9-1.4-1.11.0-1.4-1.00.8-1.2-0.7
Bone: cortical area0.60.92.50.50.5-1.41.41.1-0.4-1.2-1.20.20.1-1.21.10.10.5-1.1-0.11.6-1.5-0.2-1.1
Bone: cortical porosity0.60.62.10.90.7-0.20.20.1-1.1-0.3-0.01.01.2-0.3-0.01.10.5-0.11.4-0.30.41.31.4
Bone: cortical porosity0.50.62.30.80.6-0.10.10.1-1.0-0.2-0.00.91.1-0.3-0.01.10.5-0.11.3-0.40.41.31.5
Bone: cortical thickness0.30.51.2-0.8-0.90.5-0.5-0.70.70.50.6-0.9-0.80.5-0.7-0.8-1.00.6-0.8-0.30.4-0.7-1.1
Bone: cortical thickness0.00.00.10.20.1-0.00.0-0.0-0.3-0.20.00.00.2-0.20.10.10.2-0.30.30.1-0.00.20.1
Bone: cortical tissue density1.01.42.2-1.3-1.11.3-1.3-1.11.51.41.1-1.2-1.31.2-0.9-1.4-1.11.0-1.4-1.10.9-1.1-0.6
Condit. Reinf. active minus inactive responses0.40.52.2-0.1-0.0-0.60.60.60.2-0.7-0.6-0.4-0.4-0.50.6-0.40.2-0.6-0.61.1-1.0-0.9-1.5
Condit. Reinf. active-inactive response ratio1.01.12.90.50.7-1.31.31.3-0.3-1.3-1.40.30.0-0.91.30.20.5-1.0-0.31.7-1.7-0.5-1.3
Condit. Reinf. active responses0.20.31.4-0.5-0.50.0-0.0-0.10.5-0.10.1-0.7-0.7-0.1-0.0-0.7-0.2-0.0-0.70.4-0.3-1.0-1.2
Condit. Reinf. inactive responses0.30.40.8-0.6-0.80.8-0.8-0.90.50.70.9-0.7-0.50.4-0.8-0.6-0.50.6-0.3-0.70.8-0.4-0.1
Incentive salience index mean0.30.31.5-0.2-0.1-0.40.40.40.2-0.6-0.5-0.5-0.4-0.30.5-0.40.1-0.4-0.51.0-0.8-0.9-1.2
Condit. Reinf. lever presses0.00.00.2-0.00.0-0.10.10.2-0.0-0.4-0.3-0.1-0.10.10.20.00.0-0.1-0.20.5-0.4-0.3-0.1
Condit. Reinf. active minus inactive responses6.38.211.73.03.0-3.33.33.0-2.8-3.2-3.02.62.6-3.43.12.33.2-3.42.32.8-2.82.00.6
Condit. Reinf. active-inactive response ratio0.60.71.30.90.8-1.11.10.7-1.0-1.1-0.80.60.8-0.90.80.71.1-1.10.90.9-0.80.5-0.1
Condit. Reinf. active responses9.613.419.53.73.9-4.24.24.0-3.4-4.1-4.03.23.1-4.34.22.74.1-4.42.63.7-3.82.30.8
Condit. Reinf. inactive responses6.07.711.62.83.1-3.13.13.2-2.3-2.9-3.22.52.2-3.33.41.93.3-3.41.72.7-3.01.81.0
Condit. Reinf. lever presses20.328.136.35.96.0-5.75.75.7-5.5-5.5-5.65.65.4-5.65.55.15.5-5.54.84.4-4.64.52.8
Condit. Reinf. lever reinforcers received10.514.620.53.94.1-4.44.44.2-3.6-4.2-4.23.43.4-4.54.33.04.3-4.52.93.8-3.92.61.0
Conditioned reinforcement - actives0.81.32.31.41.2-1.11.11.0-1.5-1.0-0.91.41.5-0.90.81.51.0-0.81.50.7-0.51.41.0
Conditioned reinforcement - inactives0.30.41.3-0.2-0.20.5-0.5-0.60.20.90.70.1-0.00.8-0.70.0-0.80.80.0-1.00.90.51.1
Conditioned locomotion1.51.95.41.71.3-0.80.80.5-1.8-0.5-0.41.72.0-0.80.31.91.1-0.52.3-0.20.32.32.2
Patch foraging indifference point 0 sec5.19.412.13.43.4-3.53.53.3-3.3-3.3-3.33.23.1-3.03.13.12.9-2.82.82.8-2.72.71.9
Patch foraging indifference point AUC0.20.30.90.20.5-0.60.60.8-0.1-0.7-0.80.2-0.0-0.50.8-0.00.4-0.7-0.30.9-1.0-0.2-0.3
Delay disc. indifference point, 0s delay0.70.81.91.01.0-0.80.80.8-0.9-0.6-0.80.80.9-1.30.90.71.4-1.20.90.5-0.70.70.6
Delay disc. indifference point, 16s delay0.10.10.2-0.0-0.10.5-0.5-0.20.00.30.30.10.10.4-0.30.1-0.40.40.1-0.50.50.00.4
Delay disc. indifference point, 2s delay1.11.31.81.31.3-0.90.91.0-1.3-0.9-1.01.31.3-1.31.01.21.3-1.11.30.6-0.61.21.0
Delay disc. indifference point, 24s delay0.80.91.5-1.1-1.01.0-1.0-0.81.20.80.8-1.0-1.11.2-0.8-1.0-1.10.9-1.2-0.70.6-1.0-0.3
Delay disc. indifference point, 4s delay0.40.52.40.60.6-0.50.50.5-0.5-0.4-0.50.30.5-0.80.80.11.5-1.40.50.4-0.50.30.1
Delay disc. indifference point, 8s delay0.30.40.70.70.7-0.60.60.7-0.7-0.8-0.70.80.7-0.50.60.80.2-0.20.50.5-0.50.60.5
Indifference point function ln k0.81.43.81.51.2-0.70.70.6-1.7-0.7-0.61.61.8-0.90.41.80.9-0.51.90.10.01.81.4
Indifference point function log k0.81.43.81.51.2-0.70.70.6-1.7-0.7-0.61.61.8-0.90.41.80.9-0.51.90.10.01.81.4
Patch foraging total patch changes 0 sec4.38.110.43.13.1-3.23.23.1-3.0-3.0-3.03.02.9-2.82.92.92.7-2.62.62.6-2.52.51.9
Patch foraging total patch changes 12 sec2.02.64.81.41.6-2.12.12.1-1.2-2.0-2.11.10.9-1.72.01.01.5-1.80.62.2-2.20.60.1
Patch foraging total patch changes 18 sec2.64.06.21.82.0-2.52.52.4-1.5-2.3-2.41.51.3-2.52.41.32.2-2.31.02.5-2.50.7-0.3
Patch foraging total patch changes 24 sec0.30.61.60.70.7-0.90.90.8-0.5-0.6-0.80.40.5-1.01.00.31.3-1.20.40.8-0.90.20.2
Patch foraging total patch changes 6 sec1.92.94.31.91.9-2.12.11.8-1.8-1.7-1.81.91.8-1.71.61.91.1-1.21.61.5-1.41.61.0
Patch foraging time to switch 0 sec3.47.09.0-2.8-2.93.0-3.0-3.02.62.93.0-2.5-2.42.8-2.9-2.3-2.82.9-2.1-2.72.6-1.8-1.0
Patch foraging water rate 0 sec2.75.77.12.62.6-2.72.72.5-2.5-2.5-2.42.32.4-2.52.42.32.7-2.52.32.1-2.01.91.3
Patch foraging water rate 12 sec1.22.63.91.91.7-1.61.61.5-1.9-1.5-1.41.71.9-1.81.31.82.0-1.51.91.2-1.01.61.1
Patch foraging water rate 18 sec0.50.71.40.90.9-0.90.90.9-0.8-0.9-0.90.70.8-1.01.00.71.2-1.00.70.9-0.90.40.4
Patch foraging water rate 24 sec0.71.02.71.20.9-0.80.80.5-1.4-0.7-0.51.21.5-0.70.31.50.9-0.31.60.3-0.01.31.2
Patch foraging water rate 6 sec0.60.81.71.11.0-0.70.70.8-1.2-0.7-0.71.21.2-0.80.51.30.7-0.41.20.4-0.31.21.3
Seeking ratio, delayed vs. immediate footshock2.32.83.9-1.9-2.01.5-1.5-1.91.81.91.9-1.8-1.71.6-1.8-1.7-1.61.6-1.5-1.51.6-1.4-1.4
Distance traveled before self-admin0.20.30.7-0.7-0.60.5-0.5-0.50.70.50.5-0.5-0.70.7-0.5-0.6-0.80.7-0.7-0.30.4-0.5-0.4
Distance traveled after self-admin1.62.04.1-1.0-1.21.7-1.7-1.80.81.71.8-0.7-0.61.6-1.8-0.6-1.51.7-0.3-2.02.0-0.10.7
Extensor digitorum longus weight0.21.03.2-0.6-0.2-0.40.40.70.8-0.7-0.8-0.9-1.1-0.30.9-1.0-0.0-0.8-1.41.4-1.4-1.6-1.8
Bone: elastic displacement1.31.52.9-1.2-1.41.2-1.2-1.41.11.31.4-1.1-1.01.2-1.5-0.9-1.71.5-0.9-1.21.3-0.8-0.7
Bone: elastic work1.41.94.6-1.3-1.41.5-1.5-1.51.11.51.5-0.9-1.01.6-1.7-0.8-2.11.9-0.9-1.51.5-0.7-0.2
Bone: endosteal estimation1.53.27.01.31.6-2.22.22.3-1.0-2.2-2.30.90.7-1.92.40.71.8-2.20.22.6-2.60.1-0.4
Bone: endosteal perimeter2.35.08.21.92.2-2.82.82.7-1.6-2.6-2.81.61.3-2.52.81.32.6-2.70.92.8-2.90.80.1
Epididymis fat weight0.61.94.7-1.7-1.80.8-0.8-1.21.50.91.1-2.0-1.71.0-1.0-1.8-0.90.6-1.6-0.20.4-1.9-2.2
Delta time in closed arm before/after self-admin0.80.82.3-1.0-0.70.4-0.4-0.21.30.30.1-1.0-1.30.3-0.0-1.2-0.60.2-1.50.2-0.3-1.4-1.5
Delta time in open arm before/after self-admin2.92.94.01.71.8-2.02.02.0-1.5-1.9-2.01.51.4-1.92.01.31.8-1.91.11.9-1.91.10.2
Diff in mean of infusions in LGA sessions6.07.39.5-2.9-3.03.0-3.0-3.12.72.93.1-2.7-2.52.9-2.9-2.5-2.72.7-2.2-2.62.7-2.1-1.1
Delay discount exponential model param0.10.10.3-0.3-0.3-0.00.0-0.10.30.10.1-0.4-0.40.1-0.1-0.3-0.20.2-0.40.1-0.1-0.3-0.5
Extinction: sum of active levers before priming0.10.10.3-0.00.0-0.10.10.00.10.0-0.1-0.2-0.1-0.30.2-0.30.6-0.6-0.10.1-0.2-0.2-0.3
Active lever presses in extinction session 62.52.510.41.81.4-0.40.40.4-2.1-0.4-0.32.02.3-0.30.12.20.7-0.12.5-0.60.72.63.2
Bone: final force0.10.10.20.30.4-0.50.50.4-0.2-0.3-0.40.50.2-0.30.30.3-0.5-0.00.10.2-0.30.4-0.1
Bone: final moment0.20.30.50.50.6-0.70.70.7-0.4-0.5-0.70.60.3-0.50.50.4-0.2-0.20.10.5-0.60.4-0.1
Food consumed during 24 hour testing period2.33.16.02.12.2-1.41.41.7-1.9-1.4-1.62.22.0-1.41.62.01.9-1.31.90.8-1.02.22.5
Glucose0.10.10.7-0.2-0.3-0.10.1-0.20.20.10.2-0.4-0.3-0.0-0.1-0.40.2-0.3-0.20.1-0.0-0.5-0.9
Heart weight0.81.21.91.21.1-1.41.41.2-1.2-1.3-1.21.11.1-0.91.01.20.8-0.81.01.1-1.01.00.6
Delay discount hyperbolic model param0.10.10.2-0.4-0.40.2-0.2-0.30.30.20.3-0.4-0.40.3-0.3-0.3-0.50.4-0.4-0.10.1-0.3-0.4
Intermittent access intake day 1-15 change1.12.24.31.91.7-1.21.21.2-1.8-1.0-1.12.02.0-1.31.01.91.2-0.81.90.4-0.42.11.8
Intermittent access intake escalation1.22.64.82.01.9-1.31.31.3-2.0-1.1-1.22.22.1-1.31.12.01.2-0.92.10.4-0.52.21.9
Intermittent access intake escalation 21.41.62.61.51.5-1.21.21.2-1.5-1.1-1.11.61.6-1.01.01.61.0-0.81.50.7-0.61.51.4
Intermitt. access day 1 inactive lever presses0.72.84.6-1.6-1.62.1-2.1-1.81.61.81.8-1.3-1.42.1-1.7-1.3-1.91.8-1.3-1.91.7-1.00.3
Intermitt. access day 15 inactive lever presses1.32.74.4-1.6-1.72.0-2.0-1.91.41.81.9-1.3-1.32.1-1.9-1.2-1.92.0-1.1-1.71.8-0.8-0.0
Intermitt. access escalation Index0.00.10.5-0.10.00.1-0.10.10.1-0.1-0.10.2-0.10.4-0.10.2-0.70.5-0.2-0.00.0-0.00.3
Intermittent access day 1 total infusions0.50.71.01.01.0-0.90.91.0-0.9-0.9-0.91.00.9-0.70.81.00.7-0.70.80.7-0.70.80.6
Intermittent access day 15 total infusions1.82.74.92.02.0-1.41.41.4-2.0-1.2-1.42.22.1-1.41.22.11.3-1.02.00.6-0.72.21.8
Intermittent access terminal intake (last 3 days)2.22.94.42.02.0-1.81.81.7-1.9-1.5-1.62.12.0-1.61.42.01.3-1.21.91.1-1.11.91.4
Intermittent access total infusions1.41.72.41.41.4-1.51.51.4-1.3-1.3-1.41.41.3-1.21.31.31.1-1.11.11.2-1.21.10.6
Intermittent access day 1 locomotion0.20.20.60.50.5-0.20.20.3-0.6-0.3-0.30.70.6-0.00.10.7-0.10.10.60.1-0.00.70.8
Intermittent access day 15 total locomotion1.01.83.71.71.5-1.01.00.9-1.7-0.9-0.91.81.8-1.10.71.81.0-0.71.90.3-0.31.91.7
Intermittent access total locomotion0.81.01.41.21.1-1.11.10.9-1.1-0.9-0.91.21.2-0.90.81.20.8-0.71.10.6-0.61.20.7
Intermittent access standard deviation0.20.51.20.40.5-1.01.00.8-0.2-0.8-0.90.10.1-0.71.00.00.9-1.0-0.11.1-1.1-0.2-0.2
Left kidney weight0.31.22.9-0.10.2-0.80.80.90.4-1.0-1.0-0.7-0.7-1.11.4-0.91.4-1.6-0.91.7-1.7-1.2-1.4
Right kidney weight0.41.64.30.10.4-1.11.11.30.3-1.2-1.3-0.5-0.6-1.21.7-0.81.6-1.9-0.92.0-2.1-1.2-1.3
Cocaine induced anxiety1.21.72.4-1.6-1.51.2-1.2-1.21.51.01.1-1.5-1.61.4-1.1-1.4-1.51.3-1.5-0.60.7-1.5-1.2
Post-drug Anxiety1.31.42.0-1.4-1.31.1-1.1-1.01.41.11.0-1.3-1.41.3-1.0-1.3-1.41.1-1.4-0.70.7-1.2-0.8
Baseline Anxiety0.30.30.50.60.7-0.60.60.6-0.5-0.5-0.60.60.5-0.70.60.50.5-0.60.40.4-0.50.40.4
Tail length0.93.39.20.00.6-1.81.81.90.5-1.8-2.0-0.8-0.9-2.02.3-1.02.0-2.5-1.33.0-3.0-1.9-1.9
Length with tail0.52.15.7-0.00.3-1.31.31.40.3-1.5-1.5-0.7-0.7-1.61.8-0.91.4-2.0-1.02.4-2.3-1.6-2.0
Length without tail0.10.40.8-0.7-0.70.9-0.9-0.80.70.80.8-0.7-0.60.5-0.6-0.8-0.50.4-0.5-0.70.6-0.4-0.4
Times rat made contact with spout0.30.41.4-0.7-0.40.2-0.20.10.90.1-0.1-0.7-1.0-0.00.2-0.9-0.20.0-1.20.5-0.5-1.0-0.9
Lifetime Intake1.61.92.61.61.6-1.61.61.5-1.5-1.4-1.41.61.5-1.31.31.61.2-1.11.41.1-1.11.30.9
Liver weight, left0.30.51.5-0.7-0.40.3-0.3-0.00.90.0-0.1-1.0-1.00.00.4-1.20.4-0.7-1.10.5-0.6-1.2-0.8
Liver weight, right1.62.77.4-1.9-1.51.1-1.1-0.82.31.00.7-2.4-2.40.4-0.2-2.7-0.2-0.4-2.50.1-0.3-2.6-2.5
Locomotor activity0.91.42.21.11.2-1.51.51.3-1.0-1.3-1.31.01.0-1.21.30.91.5-1.10.81.4-1.30.70.4
Locomotor testing distance1.62.95.51.41.5-2.22.21.9-1.3-2.0-1.90.91.0-2.02.00.92.2-2.20.82.4-2.10.5-0.3
Locomotor testing rearing0.61.23.60.40.5-1.31.31.2-0.2-1.3-1.2-0.1-0.1-1.21.3-0.11.2-1.5-0.21.9-1.7-0.6-1.1
Locomotion in novel chamber0.70.92.21.21.0-0.60.60.6-1.3-0.7-0.61.21.3-0.60.51.30.9-0.61.40.3-0.21.31.5
Locomotion in novel chamber post-restriction2.43.99.22.42.1-1.31.31.5-2.5-1.5-1.42.42.6-1.51.22.51.7-1.22.70.7-0.62.63.0
Fecal boli incidents, locomotor time 10.40.61.31.00.9-0.50.50.5-1.0-0.5-0.51.11.1-0.70.41.00.5-0.31.10.1-0.11.10.7
Change in fecal boli incidents, locomotor task0.70.71.1-0.8-0.81.0-1.0-0.90.80.90.9-0.8-0.71.0-0.9-0.7-0.80.8-0.6-0.80.8-0.60.0
Time >=10cm from walls, locomotor time 11.61.73.61.61.4-0.90.91.0-1.8-1.0-1.01.71.8-1.20.71.91.0-0.71.90.4-0.41.61.6
Bouts of movement, locomotor time 10.00.00.20.20.20.2-0.2-0.0-0.20.10.00.10.2-0.20.10.10.5-0.40.3-0.30.10.10.1
Total resting periods, locomotor time 10.10.10.50.0-0.00.5-0.5-0.4-0.10.40.40.10.20.2-0.30.10.10.10.3-0.70.50.10.3
Rest time, locomotor task time 10.50.71.7-0.3-0.41.2-1.2-1.00.30.91.0-0.2-0.11.1-0.8-0.2-0.30.60.1-1.31.20.11.2
Distance moved, locomotor task time 10.81.13.00.40.5-1.31.31.2-0.2-1.2-1.30.1-0.1-1.51.2-0.00.7-1.1-0.31.7-1.7-0.4-1.6
Vertical activity count, locomotor time 10.61.53.70.80.9-1.71.71.5-0.8-1.6-1.60.70.5-1.51.40.60.8-1.10.21.9-1.80.3-0.5
Time >=10cm from walls, locomotor time 20.60.82.01.00.9-0.90.90.8-1.0-0.8-0.80.81.0-1.30.90.71.4-1.21.00.6-0.70.60.6
Bouts of movement, locomotor time 20.40.61.70.80.9-0.70.70.7-0.7-0.6-0.70.60.7-1.00.90.51.3-1.20.70.5-0.70.3-0.3
Total resting periods, locomotor time 20.20.31.00.60.6-0.40.40.4-0.5-0.3-0.40.40.6-0.70.60.41.0-0.90.60.1-0.30.3-0.3
Rest time, locomotor task time 21.72.12.8-1.6-1.51.7-1.7-1.51.61.61.5-1.3-1.41.3-1.4-1.4-1.61.5-1.4-1.41.3-1.2-1.0
Distance moved, locomotor task time 22.12.54.11.61.6-1.81.81.7-1.5-1.8-1.71.21.4-1.91.81.22.0-1.91.21.8-1.71.00.5
Vertical activity count, locomotor time 21.31.83.61.11.2-1.81.81.6-1.0-1.7-1.60.80.8-1.51.60.81.4-1.50.61.9-1.70.40.1
Light reinforcement 10.92.33.4-1.7-1.61.6-1.6-1.51.81.51.4-1.6-1.81.4-1.2-1.8-1.51.1-1.7-1.21.0-1.4-1.0
Light reinforcement 20.10.20.60.00.00.5-0.5-0.40.00.40.40.20.10.3-0.2-0.0-0.20.10.2-0.80.60.50.8
Bone: marrow area1.32.96.41.11.5-2.12.12.2-0.8-2.1-2.20.80.6-1.72.30.51.7-2.10.12.5-2.50.0-0.4
Bone: maximum diameter2.54.77.91.92.1-2.82.82.6-1.7-2.6-2.71.61.4-2.52.61.42.1-2.51.02.7-2.70.9-0.2
Bone: maximum force0.20.30.80.60.7-0.60.60.8-0.5-0.7-0.80.90.5-0.30.60.7-0.5-0.10.30.4-0.50.70.4
Bone: maximum moment0.30.51.00.70.9-0.90.91.0-0.6-0.9-1.01.00.6-0.40.80.8-0.2-0.30.30.7-0.80.70.4
Mean time between licks in bursts1.94.88.72.02.3-2.32.32.6-1.5-2.4-2.71.61.4-2.63.01.12.9-2.90.92.4-2.70.80.3
Mean num. licks in bursts2.64.05.02.22.2-2.12.12.1-2.2-2.2-2.12.12.1-2.01.92.12.1-1.82.01.8-1.71.61.1
Cd content in liver0.70.83.6-1.0-1.00.5-0.5-0.51.00.20.4-1.2-1.20.2-0.3-1.2-0.60.1-1.20.2-0.1-1.4-1.9
Co content in liver0.80.91.90.60.8-1.11.11.2-0.5-1.2-1.20.40.4-1.11.20.31.1-1.20.21.4-1.4-0.1-0.7
Cu content in liver0.30.41.0-0.3-0.2-0.30.30.20.6-0.2-0.3-0.8-0.7-0.50.6-0.90.9-1.0-0.80.7-0.8-0.9-0.7
Fe content in liver0.00.00.2-0.1-0.20.3-0.3-0.20.10.10.2-0.1-0.10.0-0.2-0.1-0.30.0-0.1-0.20.20.20.5
K content in liver0.10.10.3-0.4-0.30.3-0.3-0.20.50.30.2-0.3-0.40.6-0.2-0.4-0.20.2-0.5-0.20.2-0.40.0
Mg content in liver0.10.10.30.30.2-0.00.00.0-0.30.00.00.30.40.10.00.30.4-0.20.4-0.20.20.30.5
Mn content in liver1.31.53.5-0.7-0.91.4-1.4-1.50.51.51.5-0.3-0.31.6-1.5-0.3-1.31.5-0.0-1.91.80.21.2
Na content in liver0.80.92.11.11.0-0.70.70.6-1.1-0.5-0.51.31.3-0.50.51.20.6-0.41.30.0-0.01.41.5
Rb content in liver0.30.31.20.30.4-0.70.70.8-0.3-1.0-0.80.20.1-0.50.60.30.3-0.5-0.01.1-0.9-0.1-0.5
Se content in liver6.67.911.0-2.7-2.93.3-3.3-3.32.53.23.3-2.4-2.33.3-3.2-2.3-3.12.9-1.9-3.23.2-1.6-0.1
Sr content in liver0.10.10.30.40.2-0.20.20.1-0.5-0.2-0.10.40.5-0.4-0.10.5-0.00.10.60.00.10.40.2
Zn content in liver1.92.14.41.21.3-1.71.71.6-1.1-1.7-1.60.80.9-1.81.70.72.1-2.00.81.8-1.70.4-0.4
Bone: minimum diameter1.01.75.00.20.5-1.51.51.50.2-1.4-1.6-0.2-0.5-1.31.7-0.51.0-1.6-0.92.2-2.2-1.0-1.7
Time in familiar zone, hab. session 10.10.10.3-0.4-0.20.4-0.4-0.10.50.20.1-0.3-0.50.30.0-0.4-0.20.0-0.6-0.1-0.0-0.5-0.1
Time in novel zone, hab. session 10.10.10.9-0.2-0.3-0.20.2-0.10.20.10.1-0.4-0.3-0.1-0.1-0.4-0.1-0.0-0.30.2-0.1-0.4-1.0
Total zone transitions, hab. session 10.20.31.20.60.5-0.20.20.1-0.7-0.1-0.10.90.8-0.2-0.10.9-0.30.30.9-0.30.41.10.6
Total locomotion distance, hab. session 10.91.33.6-1.4-1.20.7-0.7-0.61.50.50.5-1.6-1.60.6-0.4-1.6-0.80.4-1.70.1-0.1-1.7-1.9
Locomotion velocity, hab. session 10.60.82.4-1.1-0.90.4-0.4-0.41.10.30.4-1.2-1.30.5-0.2-1.3-0.70.3-1.30.2-0.2-1.3-1.6
Time in familiar zone, hab. session 21.61.73.01.11.3-1.51.51.7-0.9-1.6-1.71.00.8-1.41.60.91.4-1.30.51.7-1.70.40.0
Time in novel zone, hab. session 20.70.71.6-0.6-0.91.0-1.0-1.30.41.11.3-0.7-0.30.8-1.1-0.6-0.60.5-0.0-1.21.3-0.1-0.0
Total zone transitions, hab. session 21.11.43.71.41.2-0.70.70.6-1.6-0.9-0.61.61.7-0.60.51.70.5-0.41.70.00.01.91.9
Total locomotion distance, hab. session 20.20.31.0-0.6-0.4-0.00.00.10.7-0.2-0.1-0.7-0.80.20.4-0.9-0.2-0.3-1.00.5-0.6-0.8-0.7
Locomotion velocity, hab. session 20.30.41.3-0.7-0.50.1-0.1-0.00.8-0.1-0.0-0.9-1.00.30.3-1.1-0.2-0.3-1.20.5-0.5-1.0-0.7
Novel to familiar place preference ratio0.10.10.90.30.2-0.10.1-0.1-0.40.00.10.30.4-0.3-0.00.30.1-0.20.5-0.30.20.51.0
Novelty place preference0.10.10.70.20.10.1-0.1-0.2-0.20.20.20.10.3-0.1-0.10.10.2-0.20.4-0.40.30.40.8
Time in novel zone, NPP test0.10.10.70.40.3-0.10.1-0.0-0.4-0.00.00.30.5-0.30.00.30.3-0.30.6-0.20.20.50.8
Total zone transitions, NPP test0.20.31.70.40.30.2-0.2-0.2-0.50.20.30.60.70.5-0.30.6-0.10.30.7-0.70.71.01.3
Total locomotion distance, NPP test1.11.53.2-1.5-1.41.1-1.1-1.21.51.11.1-1.6-1.51.3-0.7-1.8-0.80.4-1.5-0.70.6-1.4-0.9
Locomotion velocity, NPP test1.62.24.3-1.8-1.71.4-1.4-1.51.81.41.5-2.0-1.81.6-1.0-2.1-1.00.7-1.8-1.00.9-1.6-1.0
Intraocular pressure0.50.71.91.00.7-0.60.60.3-1.2-0.4-0.31.11.2-0.60.01.20.2-0.01.4-0.00.21.41.1
Delta distance traveled before/after self-admin0.50.52.20.70.50.1-0.1-0.1-0.90.00.10.91.0-0.1-0.21.00.20.21.2-0.60.61.21.5
Delta ambulatory time before/after self-admin0.50.62.50.70.40.1-0.1-0.2-0.90.10.20.91.0-0.1-0.31.00.10.31.2-0.70.71.31.6
Parametrial fat weight0.20.41.2-0.8-0.70.4-0.4-0.40.90.60.4-0.8-0.90.1-0.3-0.9-0.50.1-0.9-0.20.1-0.9-1.1
Pavlov. Cond. lever latency0.91.11.9-1.0-1.21.2-1.2-1.40.91.31.4-1.0-0.80.8-1.3-0.9-1.11.0-0.6-1.31.3-0.6-0.4
Pavlov. Cond. magazine entry latency2.93.85.92.02.1-2.22.22.3-1.9-2.4-2.31.81.6-1.92.21.71.8-2.11.42.2-2.21.20.5
Pavlov. Cond. change in total contacts0.50.60.90.80.8-0.80.80.8-0.8-0.9-0.80.70.7-0.50.90.70.7-0.90.60.7-0.70.60.6
Pavlov. Cond. index score2.12.64.31.51.7-1.81.82.0-1.4-2.1-2.01.31.2-1.52.01.21.7-1.80.92.0-2.00.70.3
Pavlov. Cond. latency score2.02.54.21.51.7-1.81.82.0-1.4-2.1-2.01.31.2-1.41.91.31.6-1.70.91.9-1.90.80.3
Pavlov. Cond. lever contacts0.70.81.60.70.9-1.01.01.2-0.6-1.2-1.20.60.5-0.61.20.60.9-0.90.31.3-1.30.2-0.0
Pavlov. Cond. magazine entry number2.83.55.5-1.9-2.02.1-2.1-2.21.82.32.2-1.6-1.52.0-2.1-1.6-1.92.0-1.3-2.12.1-1.1-0.3
Pavlov. Cond. intertrial magazine entries2.42.94.3-1.8-2.01.8-1.8-2.11.72.02.0-1.9-1.61.7-1.8-1.8-1.21.5-1.3-1.71.7-1.6-0.6
Pavlov. Cond. lever-magazine prob. diff.1.72.13.51.31.5-1.61.61.8-1.2-1.9-1.91.21.0-1.31.81.11.5-1.50.71.8-1.80.60.3
Pavlov. Cond. response bias0.81.01.90.91.1-1.11.11.3-0.8-1.4-1.30.80.7-0.81.30.71.0-1.10.41.3-1.30.40.1
Pavlov. Cond. lever latency21.328.937.3-6.1-6.15.6-5.6-5.65.85.65.5-5.8-5.75.5-5.4-5.4-5.55.4-5.2-4.24.4-5.0-3.3
Pavlov. Cond. magazine entry latency5.76.910.03.13.0-2.62.62.6-3.2-2.7-2.63.13.1-2.52.33.12.2-2.12.91.9-1.82.71.8
Pavlov. Cond. change in total contacts11.418.323.44.84.7-4.54.54.2-4.8-4.5-4.24.54.6-4.54.14.34.6-4.44.43.3-3.33.92.6
Pavlov. Cond. index score15.620.926.95.25.1-4.84.84.7-5.1-4.8-4.64.94.9-4.64.44.84.6-4.54.63.6-3.64.22.7
Pavlov. Cond. latency score14.018.524.34.94.9-4.44.44.4-4.9-4.5-4.34.74.7-4.34.14.64.3-4.14.43.3-3.34.12.8
Pavlov. Cond. lever contacts19.827.334.85.95.9-5.55.55.5-5.7-5.5-5.45.65.5-5.45.25.35.4-5.25.04.2-4.34.73.1
Pavlov. Cond. magazine entry number7.08.612.7-3.4-3.23.0-3.0-2.83.63.12.7-3.2-3.42.8-2.6-3.3-2.92.7-3.3-2.22.0-2.9-1.9
Pavlov. Cond. intertrial magazine entries0.40.51.4-0.20.1-0.60.60.60.6-0.3-0.6-0.5-0.7-0.80.9-0.80.6-0.9-0.90.9-1.1-0.9-1.2
Pavlov. Cond. lever-magazine prob. diff.14.519.324.65.04.9-4.64.64.5-4.9-4.7-4.54.74.7-4.44.34.54.5-4.44.43.5-3.54.02.6
Pavlov. Cond. response bias20.227.434.65.95.9-5.55.55.5-5.7-5.6-5.45.65.5-5.45.25.35.3-5.25.14.3-4.34.73.0
Time in closed arm before self-admin0.50.61.71.00.7-0.40.40.4-1.2-0.5-0.31.01.2-0.30.11.30.4-0.11.3-0.00.11.31.3
Time in closed arm after self-admin1.01.02.1-0.8-0.81.3-1.3-1.10.81.31.2-0.5-0.61.1-1.2-0.5-1.31.3-0.5-1.41.3-0.30.2
Time in open arm before self-admin2.12.33.0-1.7-1.71.5-1.5-1.71.61.61.7-1.6-1.61.6-1.5-1.6-1.41.4-1.4-1.31.4-1.3-0.8
Time in open arm after self-admin0.80.92.60.50.7-1.31.31.2-0.4-1.2-1.20.30.2-0.91.20.20.9-1.1-0.11.6-1.5-0.2-0.6
Bone: periosteal estimation1.43.06.71.21.4-2.32.32.2-0.9-2.1-2.20.80.6-1.92.20.61.6-2.20.22.6-2.50.1-0.7
Bone: periosteal perimeter2.03.46.71.41.7-2.42.42.3-1.1-2.2-2.41.10.8-2.12.30.81.9-2.10.42.6-2.60.3-0.5
Bone: post-yield work0.50.81.70.81.0-1.01.01.3-0.6-1.1-1.31.00.6-0.61.00.80.1-0.50.31.1-1.10.40.0
Progressive ratio test 1 active lever presses0.20.20.60.0-0.10.4-0.4-0.4-0.10.50.50.20.20.4-0.60.3-0.60.70.3-0.70.70.50.4
Progressive ratio test 1 breakpoint0.20.20.50.0-0.10.4-0.4-0.4-0.10.50.50.20.20.3-0.60.2-0.50.70.3-0.70.70.50.4
Progressive ratio test 1 inactive lever presses0.30.41.2-0.4-0.40.8-0.8-0.50.30.60.6-0.0-0.20.8-0.70.0-1.11.1-0.2-0.80.80.20.6
Progressive ratio test 2 active lever presses0.60.71.10.90.9-1.01.00.9-0.9-0.8-0.90.80.8-1.00.80.81.0-0.90.80.8-0.80.70.1
Progressive ratio test 2 breakpoint0.60.71.10.90.9-1.01.00.9-0.9-0.8-0.90.80.9-1.00.80.81.0-0.90.80.8-0.70.70.1
Progressive ratio test 2 inactive lever presses0.10.20.40.50.4-0.60.60.5-0.5-0.5-0.50.50.5-0.50.40.50.4-0.30.50.5-0.40.40.1
Incentive Sensitization - Responses1.41.93.11.41.4-1.81.81.5-1.3-1.5-1.51.11.2-1.71.51.11.5-1.51.01.6-1.40.90.2
Incentive Sensitization - Breakpoint1.31.72.81.31.3-1.71.71.4-1.2-1.4-1.41.11.1-1.61.41.11.5-1.41.01.5-1.30.80.2
Sum of active levers in priming session hrs 5-60.10.10.40.10.10.3-0.3-0.2-0.10.10.20.10.20.1-0.00.00.5-0.30.3-0.30.20.20.6
Progressive ratio0.20.41.20.70.6-0.40.40.4-0.8-0.5-0.30.90.8-0.10.20.90.2-0.00.90.1-0.01.11.1
Food seeking constrained by brief footshock2.32.84.61.71.9-1.81.81.9-1.4-1.6-1.91.51.4-2.02.01.22.1-2.11.21.5-1.71.00.7
Seeking ratio, punishment vs. effort0.71.02.40.60.8-1.11.11.2-0.3-1.0-1.20.30.2-1.51.40.01.4-1.5-0.01.3-1.5-0.3-0.7
Retroperitoneal fat weight1.87.927.9-3.2-2.80.9-0.9-1.13.61.00.9-4.0-4.00.8-0.4-4.2-0.9-0.2-4.21.1-1.0-4.8-5.3
Reaction time number correct0.20.42.00.40.20.3-0.3-0.4-0.50.30.40.70.70.3-0.50.8-0.30.60.9-0.80.91.01.4
Reaction time mean minus median0.82.03.01.31.5-1.61.61.7-1.1-1.6-1.71.11.0-1.61.70.91.6-1.70.81.6-1.70.6-0.0
Reaction time mean minus median AUC0.82.02.71.61.6-1.51.51.6-1.4-1.5-1.61.51.4-1.51.61.31.6-1.51.21.3-1.41.10.6
Reaction time num false alarms1.92.74.3-2.0-1.91.3-1.3-1.42.01.31.4-1.9-2.01.8-1.2-2.0-1.81.3-2.1-0.80.8-1.9-1.5
Reaction time num false alarms AUC1.11.72.6-1.5-1.51.2-1.2-1.31.51.21.2-1.5-1.51.6-1.1-1.5-1.41.2-1.5-0.80.9-1.3-0.8
Reaction time trials correct on left0.20.42.00.40.20.3-0.3-0.4-0.50.30.40.70.70.3-0.50.8-0.30.60.9-0.80.91.01.4
Reaction time trials on left0.20.52.10.40.20.3-0.3-0.3-0.60.30.40.70.80.3-0.50.8-0.20.60.9-0.80.91.11.5
Reaction time mean0.10.20.6-0.5-0.30.1-0.1-0.00.70.30.0-0.6-0.70.30.1-0.7-0.2-0.3-0.80.1-0.2-0.8-0.6
Reaction time mean AUC0.30.51.0-0.8-0.60.6-0.6-0.51.00.70.5-0.9-0.90.7-0.3-1.0-0.50.1-1.0-0.40.2-0.9-0.5
Median of all reaction times0.40.61.2-0.9-0.80.7-0.7-0.61.10.80.6-0.9-1.00.9-0.4-1.1-0.70.3-1.1-0.40.3-1.0-0.5
Reaction time omissions0.10.10.80.20.3-0.40.40.3-0.1-0.3-0.4-0.00.0-0.50.6-0.20.5-0.9-0.00.4-0.50.0-0.2
Reaction time false alarm rate1.41.93.5-1.7-1.61.1-1.1-1.11.71.11.1-1.7-1.81.5-0.9-1.8-1.30.9-1.9-0.50.5-1.7-1.4
Reaction time premature initiation rate2.43.38.21.11.4-2.22.22.3-0.8-2.3-2.40.60.4-2.12.40.51.6-2.2-0.02.9-2.9-0.3-1.3
Reaction time premature initiations1.42.65.01.31.5-1.91.92.0-1.2-2.0-2.11.00.9-1.92.01.01.4-1.80.62.2-2.20.4-0.4
Std. dev. reaction times0.61.02.50.60.8-1.21.21.3-0.3-1.1-1.30.20.2-1.11.40.11.2-1.5-0.11.5-1.6-0.3-0.8
Reaction time trials completed0.20.52.10.40.20.3-0.3-0.3-0.60.30.40.70.80.3-0.50.8-0.20.60.9-0.80.91.11.5
Reaction time trials AUC0.20.31.70.50.30.1-0.1-0.2-0.60.20.30.70.70.1-0.30.7-0.10.40.9-0.70.71.01.3
Run reversals in cocaine runway, females1.21.23.9-0.8-0.4-0.50.50.61.1-0.5-0.7-1.1-1.4-0.30.8-1.30.1-0.6-1.81.4-1.4-1.9-2.0
Run reversals in cocaine runway, males0.00.00.10.20.30.1-0.10.1-0.00.1-0.10.40.20.10.10.2-0.10.10.1-0.20.10.30.1
Latency to leave start box in cocaine runway2.42.74.6-1.8-1.81.8-1.8-1.71.81.71.7-1.7-1.82.2-1.5-1.7-1.61.5-1.7-1.51.4-1.5-0.2
Latency to leave start box in cocaine runway, F2.22.54.0-1.9-1.71.6-1.6-1.42.01.41.4-1.8-1.91.8-1.2-2.0-1.41.1-1.9-1.00.9-1.7-0.8
Latency to leave start box in cocaine runway, M0.50.41.2-0.4-0.50.8-0.8-0.80.30.70.8-0.3-0.21.1-0.8-0.1-0.70.8-0.1-0.90.9-0.10.7
Std. dev. time between licks in bursts1.01.33.10.71.0-1.21.21.4-0.4-1.3-1.50.40.2-1.31.70.11.5-1.6-0.11.6-1.8-0.2-0.4
Total sessions with >9 infusions1.92.33.21.81.7-1.61.61.6-1.7-1.5-1.61.81.7-1.31.41.81.3-1.11.51.2-1.11.61.2
Short access day 1 total inactive lever presses0.00.00.40.10.2-0.10.1-0.0-0.00.20.00.10.1-0.10.10.10.2-0.20.1-0.10.10.20.6
Short access day 10 total inactive lever presses0.71.62.6-1.3-1.41.4-1.4-1.41.21.31.4-1.2-1.21.6-1.4-1.0-1.61.5-1.1-1.21.2-0.9-0.1
Short access day 1 total infusions2.83.75.12.02.1-2.22.22.1-1.9-2.0-2.11.91.8-2.02.11.82.0-2.01.61.9-1.81.40.8
Short access day 10 total infusions0.91.11.41.21.2-1.11.11.2-1.1-1.1-1.11.11.1-0.81.11.10.9-0.91.01.0-0.90.90.8
Short access total infusions1.72.22.91.71.7-1.61.61.5-1.7-1.4-1.51.71.7-1.31.41.71.3-1.21.51.1-1.11.51.3
Short access day 1 locomotion2.73.45.92.22.1-1.71.71.7-2.3-1.6-1.62.42.4-1.51.32.41.3-1.02.30.9-0.92.41.8
Short access day 10 total locomotion0.91.72.31.51.5-1.21.21.3-1.5-1.4-1.31.41.5-1.21.31.41.3-1.21.41.0-1.01.41.1
Short access total locomotion0.91.12.31.31.2-0.90.90.9-1.3-0.8-0.81.41.4-0.60.61.50.5-0.41.40.4-0.41.51.4
One hour access (0.3 mA shock)1.01.21.61.21.1-1.31.31.1-1.3-1.2-1.11.01.2-1.11.01.21.1-1.01.11.1-0.90.90.3
Compulsive drug intake0.60.71.8-0.4-0.71.0-1.0-1.10.10.91.1-0.2-0.00.9-1.20.0-0.81.10.3-1.31.40.30.5
One hour access (shock baseline)1.31.92.51.61.6-1.51.51.5-1.5-1.4-1.41.51.5-1.31.31.51.4-1.31.41.1-1.11.30.9
Social response proportion0.50.61.1-0.9-0.80.9-0.9-0.61.00.70.6-0.9-1.00.8-0.4-1.1-0.60.4-1.0-0.50.4-1.0-0.4
Social responses0.70.92.7-1.2-1.00.5-0.5-0.51.40.50.4-1.4-1.50.6-0.2-1.5-0.50.2-1.60.1-0.2-1.6-1.0
Social time3.54.87.1-2.2-2.42.6-2.6-2.72.02.52.6-2.1-1.82.4-2.5-1.9-2.12.1-1.5-2.42.4-1.3-0.2
Soleus weight0.51.43.8-0.8-0.3-0.40.40.81.2-0.6-0.9-1.2-1.5-0.11.1-1.50.2-0.8-2.01.6-1.7-1.9-1.6
Bone: stiffness0.10.11.1-0.10.00.2-0.20.10.30.2-0.10.2-0.20.30.0-0.1-1.00.4-0.5-0.30.00.20.1
Tibialis anterior weight0.20.51.50.30.6-0.80.81.0-0.2-1.0-1.00.20.0-0.71.10.10.5-1.0-0.21.2-1.2-0.3-0.3
Time to tail flick, vehicle, before self-admin0.20.20.70.10.1-0.50.50.5-0.1-0.6-0.6-0.0-0.1-0.40.40.1-0.0-0.1-0.20.8-0.7-0.3-0.8
Time to tail flick, vehicle, after self-admin1.21.62.11.41.4-1.41.41.5-1.3-1.4-1.41.31.2-1.21.31.31.1-1.11.11.2-1.21.10.7
Time to tail flick, test, before self-admin0.60.61.60.20.4-0.80.80.9-0.0-0.9-1.00.0-0.1-1.01.0-0.10.7-0.9-0.41.3-1.3-0.5-1.2
Time to tail flick, test, after self-admin0.30.30.7-0.1-0.0-0.30.30.40.3-0.3-0.4-0.5-0.4-0.50.6-0.50.7-0.8-0.50.8-0.8-0.8-0.7
Delta time to tail flick, vehicle, before/after SA1.21.22.21.31.2-0.80.80.9-1.3-0.8-0.81.41.4-0.90.71.40.9-0.71.40.4-0.41.51.4
Delta time to tail flick, test, before/after SA0.60.61.1-0.7-0.81.0-1.0-1.00.61.01.0-0.6-0.51.1-0.9-0.5-0.60.7-0.3-1.01.0-0.30.4
Tibia length1.33.56.92.31.9-1.71.71.4-2.6-1.8-1.32.22.5-1.71.02.51.4-1.02.61.0-0.72.31.9
Ambulatory time before self-admin0.50.81.3-0.8-0.81.0-1.0-1.00.71.01.0-0.5-0.61.1-1.1-0.5-1.11.1-0.5-1.01.1-0.3-0.0
Ambulatory time after self-admin1.61.84.8-0.7-1.01.6-1.6-1.80.41.71.8-0.3-0.11.4-1.8-0.2-1.21.60.3-2.12.20.41.3
Bone: tissue strength0.70.72.3-0.1-0.30.6-0.6-0.7-0.20.60.80.40.30.8-1.10.6-1.51.50.5-1.11.20.70.7
Total heroin consumption0.00.00.3-0.1-0.10.3-0.3-0.20.10.10.2-0.1-0.10.5-0.1-0.1-0.00.1-0.1-0.20.2-0.00.5
Bone: trabecular number0.61.03.3-1.1-1.10.7-0.7-0.71.00.80.7-0.8-1.01.2-1.0-0.7-1.81.4-1.1-0.50.6-1.0-1.0
Bone: trabecular spacing0.81.12.31.21.0-0.70.70.5-1.3-0.6-0.51.11.4-1.10.61.11.4-0.91.50.1-0.11.41.5
Bone: trabecular thickness0.40.51.9-0.8-0.60.2-0.2-0.10.90.10.0-0.9-1.10.3-0.0-1.0-0.50.0-1.20.5-0.4-1.4-1.3
Bone: trabecular tissue density0.91.32.6-1.4-1.11.2-1.2-1.01.61.20.9-1.4-1.51.0-0.6-1.6-0.90.6-1.6-0.80.5-1.3-0.8
Water consumed over 24 hours0.60.91.3-1.1-1.01.0-1.0-0.91.11.00.8-1.0-1.10.8-0.8-1.0-1.01.0-1.1-0.70.7-0.9-0.5
Number of responses in last shaping day1.21.34.4-1.3-1.10.4-0.4-0.31.40.10.2-1.5-1.60.7-0.2-1.4-0.90.4-1.80.6-0.4-1.9-2.1