Hub : Traits

Condit. Reinf. lever presses

Pavlovian Conditioned Approach, conditioned reinforcement, sign-tracking, number of lever presses (contacts) during the conditoned reinforcement session

Tags: Behavior · Pavlovian conditioned approach · Conditioned reinforcement

Project: p50_paul_meyer_2014

3 loci · 8 genes with independent associations · 175 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr1	160823976	166558180	173	6	7.96e-10	2.34e-09	1e+00	LOC120099897 Map6 Plekhb1 Relt Tsku Wnt11
2	chr8	117463629	118343328	1	1	1.32e-16	4.09e-01	1e+00	Mst1
3	chr9	83390749	84777604	1	1	0.00e+00	3.01e-01	1e+00	Retreg2

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	3838.58	1	1	12.5	0	1.00e+00	Retreg2
BMI without tail	144009.17	1	1	12.5	0	1.00e+00	Retreg2
Body weight	5.42	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Epididymis fat weight	54228.13	2	2	25	0	1.00e+00	Mst1 Retreg2
Glucose	1235.87	2	2	25	0	1.00e+00	Mst1 Retreg2
Heart weight	13509	1	1	12.5	0	1.00e+00	Retreg2
Left kidney weight	141259.46	1	1	12.5	0	1.00e+00	Retreg2
Right kidney weight	58428.02	2	2	25	0	1.00e+00	Mst1 Retreg2
Tail length	92117.69	1	1	12.5	0	1.00e+00	Retreg2
Length with tail	3073.73	2	2	25	0	1.00e+00	Mst1 Retreg2
Length without tail	64659.67	2	2	25	0	1.00e+00	Mst1 Retreg2
Liver weight, left	7266.72	2	2	25	0	1.00e+00	Mst1 Retreg2
Liver weight, right	143.89	2	2	25	0	1.00e+00	Mst1 Retreg2
Parametrial fat weight	615.65	1	1	12.5	0	1.00e+00	Retreg2
Retroperitoneal fat weight	1610.97	7	2	25	-1	7.40e-11	B3gnt6 Capn5 Gdpd4 LOC134484907 Mst1 Retreg2 Thap12
Intraocular pressure	40071.91	1	1	12.5	0	1.00e+00	Retreg2
Extensor digitorum longus weight	4682.69	1	1	12.5	0	1.00e+00	Retreg2
Soleus weight	115.65	1	1	12.5	0	1.00e+00	Retreg2
Tibialis anterior weight	4881.94	1	1	12.5	0	1.00e+00	Retreg2
Tibia length	1639.71	2	2	25	0	1.00e+00	Mst1 Retreg2
Number of licking bursts	157119.65	1	1	12.5	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	106196.53	1	1	12.5	0	1.00e+00	Retreg2
Times rat made contact with spout	305.36	1	1	12.5	0	1.00e+00	Retreg2
Mean time between licks in bursts	199507.71	1	1	12.5	0	1.00e+00	Retreg2
Mean num. licks in bursts	142600.29	1	1	12.5	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	94042.02	1	1	12.5	0	1.00e+00	Retreg2
Water consumed over 24 hours	103408.69	1	1	12.5	0	1.00e+00	Retreg2
Patch foraging indifference point 0 sec	115003.89	1	1	12.5	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	66581.81	2	2	25	0	1.00e+00	Mst1 Retreg2
Indifference point function ln k	71040.92	2	2	25	0	1.00e+00	Mst1 Retreg2
Indifference point function log k	71040.92	2	2	25	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 0 sec	120264.14	1	1	12.5	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	5448.59	2	2	25	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 18 sec	58889.67	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 24 sec	83554.6	2	2	25	0	1.00e+00	Mst1 Retreg2
Patch foraging total patch changes 6 sec	32639.62	1	1	12.5	0	1.00e+00	Retreg2
Patch foraging time to switch 0 sec	156618.53	1	1	12.5	0	1.00e+00	Retreg2
Patch foraging water rate 0 sec	148807.58	1	1	12.5	0	1.00e+00	Retreg2
Patch foraging water rate 12 sec	161858.08	1	1	12.5	0	1.00e+00	Retreg2
Patch foraging water rate 18 sec	103280.07	1	1	12.5	0	1.00e+00	Retreg2
Patch foraging water rate 24 sec	2351.36	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Patch foraging water rate 6 sec	3954.86	1	1	12.5	0	1.00e+00	Retreg2
Locomotor activity	15.72	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Locomotor testing distance	44732.22	2	2	25	0	1.00e+00	Mst1 Retreg2
Locomotor testing rearing	76214.5	2	2	25	0	1.00e+00	Mst1 Retreg2
Light reinforcement 1	155242.72	1	1	12.5	0	1.00e+00	Retreg2
Light reinforcement 2	53965.57	2	2	25	0	1.00e+00	Mst1 Retreg2
Reaction time number correct	153465.22	1	1	12.5	0	1.00e+00	Retreg2
Reaction time mean minus median	205810.62	1	1	12.5	0	1.00e+00	Retreg2
Reaction time mean minus median AUC	104201.52	2	2	25	0	1.00e+00	Mst1 Retreg2
Reaction time num false alarms	28542.61	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Reaction time num false alarms AUC	53251.53	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Reaction time trials correct on left	153465.22	1	1	12.5	0	1.00e+00	Retreg2
Reaction time trials on left	149991.58	1	1	12.5	0	1.00e+00	Retreg2
Reaction time mean	94380.53	1	1	12.5	0	1.00e+00	Retreg2
Reaction time mean AUC	113341.21	1	1	12.5	0	1.00e+00	Retreg2
Median of all reaction times	31417.12	1	1	12.5	0	1.00e+00	Retreg2
Reaction time omissions	34267.91	1	1	12.5	0	1.00e+00	Retreg2
Reaction time false alarm rate	451.08	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Reaction time premature initiation rate	36877.02	1	1	12.5	0	1.00e+00	Retreg2
Reaction time premature initiations	138718.63	1	1	12.5	0	1.00e+00	Retreg2
Std. dev. reaction times	74746.42	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Reaction time trials completed	149991.58	1	1	12.5	0	1.00e+00	Retreg2
Reaction time trials AUC	151696.42	1	1	12.5	0	1.00e+00	Retreg2
Social response proportion	17657.99	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Social responses	2847.52	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Social time	44238.34	1	1	12.5	0	1.00e+00	Retreg2
Conditioned locomotion	6074.35	1	1	12.5	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	65812.39	1	1	12.5	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	64247.35	1	1	12.5	0	1.00e+00	Retreg2
Cocaine response before conditioning	2800.41	1	1	12.5	0	1.00e+00	Retreg2
Saline control response	6522.43	2	2	25	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active minus inactive responses	2145.96	15	1	12.5	0.99	8.28e-22	Fam168a Fchsd2 Gdpd5 LOC120099897 Map6 Mrpl48 Mst1 P2ry6 Plekhb1 Rab6a Relt Retreg2 Rnf121 Serpinh1 Slco2b1
Condit. Reinf. active-inactive response ratio	91582.24	1	1	12.5	0	1.00e+00	Retreg2
Condit. Reinf. active responses	48.6	48	2	25	1	5.40e-277	Arap1 Arhgef17 Arrb1 Atg16l2 B3gnt6 Capn5 Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 Lrrc32 Map6 Mogat2 Mrpl48 Mst1 Numa1 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgm2l1 Plekhb1 Ppme1 Rab6a Relt Retreg2 Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Thap12 Tsku Uvrag Wnt11
Condit. Reinf. inactive responses	14049.2	3	2	25	0	1.00e+00	Mst1 Plekhb1 Retreg2
Condit. Reinf. lever reinforcers received	20.24	49	2	25	0.92	7.88e-124	Arap1 Arhgef17 Arrb1 Atg16l2 B3gnt6 Capn5 Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 Lrrc32 Map6 Mogat2 Mrpl48 Mst1 Numa1 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgm2l1 Plekhb1 Ppme1 Rab6a Relt Retreg2 Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Thap12 Tsku Ucp2 Uvrag Wnt11
Pavlov. Cond. lever latency	56.08	51	50	625	0.29	7.79e-08	Acer3 Arap1 Arhgef17 Arrb1 Atg16l2 B3gnt6 Capn5 Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Mst1 Numa1 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgm2l1 Plekhb1 Ppme1 Rab6a Relt Retreg2 Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Thap12 Tsku Ucp2 Uvrag Wnt11
Pavlov. Cond. magazine entry latency	24773.4	2	2	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. change in total contacts	361.51	50	14	175	-0.74	1.01e-56	Acer3 Arap1 Arhgef17 Arrb1 Atg16l2 B3gnt6 Capn5 Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Numa1 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgm2l1 Plekhb1 Ppme1 Rab6a Relt Retreg2 Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Thap12 Tsku Ucp2 Uvrag Wnt11
Pavlov. Cond. index score	161.66	51	6	75	-0.63	3.87e-37	Acer3 Arap1 Arhgef17 Arrb1 Atg16l2 B3gnt6 Capn5 Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Mst1 Numa1 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgm2l1 Plekhb1 Ppme1 Rab6a Relt Retreg2 Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Thap12 Tsku Ucp2 Uvrag Wnt11
Pavlov. Cond. latency score	192.08	51	2	25	-0.66	6.50e-43	Acer3 Arap1 Arhgef17 Arrb1 Atg16l2 B3gnt6 Capn5 Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Mst1 Numa1 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgm2l1 Plekhb1 Ppme1 Rab6a Relt Retreg2 Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Thap12 Tsku Ucp2 Uvrag Wnt11
Pavlov. Cond. lever contacts	88.12	51	50	625	-0.46	9.56e-19	Acer3 Arap1 Arhgef17 Arrb1 Atg16l2 B3gnt6 Capn5 Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Mst1 Numa1 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgm2l1 Plekhb1 Ppme1 Rab6a Relt Retreg2 Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Thap12 Tsku Ucp2 Uvrag Wnt11
Pavlov. Cond. magazine entry number	2825.98	4	2	25	0.98	5.48e-04	Capn5 Gdpd4 Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	52501.71	2	2	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	151.46	51	2	25	-0.62	8.72e-37	Acer3 Arap1 Arhgef17 Arrb1 Atg16l2 B3gnt6 Capn5 Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Mst1 Numa1 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgm2l1 Plekhb1 Ppme1 Rab6a Relt Retreg2 Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Thap12 Tsku Ucp2 Uvrag Wnt11
Pavlov. Cond. response bias	38.41	51	50	625	-0.11	4.48e-02	Acer3 Arap1 Arhgef17 Arrb1 Atg16l2 B3gnt6 Capn5 Dgat2 Dnajb13 Emsy Fam168a Fchsd2 Gdpd4 Gdpd5 Gucy2e Lamtor1 Lipt2 LOC100912071 LOC120097346 LOC120099888 LOC120099889 LOC120099891 LOC120099897 LOC134484907 Lrrc32 Map6 Mogat2 Mrpl48 Mst1 Numa1 P2ry2 P2ry6 P4ha3 Pak1 Pde2a Pgm2l1 Plekhb1 Ppme1 Rab6a Relt Retreg2 Rnf121 Rnf169 Serpinh1 Slco2b1 Stard10 Thap12 Tsku Ucp2 Uvrag Wnt11
Conditioned reinforcement - actives	191492.54	1	1	12.5	0	1.00e+00	Retreg2
Conditioned reinforcement - inactives	77543.68	2	2	25	0	1.00e+00	Mst1 Retreg2
Conditioned locomotion	41346.85	1	1	12.5	0	1.00e+00	Retreg2
Intermittent access intake day 1-15 change	105304.97	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation	104773.43	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation 2	107995.31	1	1	12.5	0	1.00e+00	Retreg2
Intermitt. access day 1 inactive lever presses	118279.42	2	2	25	0	1.00e+00	Mst1 Retreg2
Intermitt. access day 15 inactive lever presses	208241.66	1	1	12.5	0	1.00e+00	Retreg2
Intermitt. access escalation Index	92516.01	2	2	25	0	1.00e+00	Mst1 Retreg2
Intermittent access day 1 total infusions	155525.68	1	1	12.5	0	1.00e+00	Retreg2
Intermittent access day 15 total infusions	131485.34	1	1	12.5	0	1.00e+00	Retreg2
Intermittent access terminal intake (last 3 days)	83205.14	1	1	12.5	0	1.00e+00	Retreg2
Intermittent access total infusions	675.9	1	1	12.5	0	1.00e+00	Retreg2
Intermittent access day 1 locomotion	104459.41	1	1	12.5	0	1.00e+00	Retreg2
Intermittent access day 15 total locomotion	177836.92	1	1	12.5	0	1.00e+00	Retreg2
Intermittent access total locomotion	711.59	1	1	12.5	0	1.00e+00	Retreg2
Intermittent access standard deviation	100956.84	2	2	25	0	1.00e+00	Mst1 Retreg2
Cocaine induced anxiety	160280.46	1	1	12.5	0	1.00e+00	Retreg2
Post-drug Anxiety	20460.83	1	1	12.5	0	1.00e+00	Retreg2
Baseline Anxiety	103471.3	1	1	12.5	0	1.00e+00	Retreg2
Lifetime Intake	6830.03	1	1	12.5	0	1.00e+00	Retreg2
Incentive Sensitization - Responses	163579.25	1	1	12.5	0	1.00e+00	Retreg2
Incentive Sensitization - Breakpoint	142790.8	1	1	12.5	0	1.00e+00	Retreg2
Progressive ratio test 1 active lever presses	99872.69	1	1	12.5	0	1.00e+00	Retreg2
Progressive ratio test 1 breakpoint	96247.61	1	1	12.5	0	1.00e+00	Retreg2
Progressive ratio test 1 inactive lever presses	75556.75	2	2	25	0	1.00e+00	Mst1 Retreg2
Progressive ratio test 2 active lever presses	57222.6	1	1	12.5	0	1.00e+00	Retreg2
Progressive ratio test 2 breakpoint	34975.96	1	1	12.5	0	1.00e+00	Retreg2
Progressive ratio test 2 inactive lever presses	164104.71	1	1	12.5	0	1.00e+00	Retreg2
Total sessions with >9 infusions	3995.08	2	2	25	0	1.00e+00	Mst1 Retreg2
Short access day 1 total inactive lever presses	57219.08	2	2	25	0	1.00e+00	Mst1 Retreg2
Short access day 10 total inactive lever presses	108578.43	2	2	25	0	1.00e+00	Mst1 Retreg2
Short access day 1 total infusions	111479.43	1	1	12.5	0	1.00e+00	Retreg2
Short access day 10 total infusions	38157.63	2	2	25	0	1.00e+00	Mst1 Retreg2
Short access total infusions	33946.03	1	1	12.5	0	1.00e+00	Retreg2
Short access day 1 locomotion	84055.65	1	1	12.5	0	1.00e+00	Retreg2
Short access day 10 total locomotion	90801.14	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Short access total locomotion	34144.06	2	2	25	0	1.00e+00	Mst1 Retreg2
Compulsive drug intake	65439.45	1	1	12.5	0	1.00e+00	Retreg2
One hour access (0.3 mA shock)	9669.44	1	1	12.5	0	1.00e+00	Retreg2
One hour access (shock baseline)	140263.4	1	1	12.5	0	1.00e+00	Retreg2
Number of responses in last shaping day	51289.19	1	1	12.5	0	1.00e+00	Retreg2
Context. condit. distance diff. score	970.59	1	1	12.5	0	1.00e+00	Retreg2
Locomotion velocity, session 1	14615.25	1	1	12.5	0	1.00e+00	Retreg2
Locomotion distance, session 1	4416.18	1	1	12.5	0	1.00e+00	Retreg2
Locomotion velocity, session 2	4702.2	2	2	25	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 2	2393.66	1	1	12.5	0	1.00e+00	Retreg2
Locomotion velocity, session 3	2332.53	1	1	12.5	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	12.5	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	2943.11	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving duration, day 3	6074.03	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, session 7	708.6	2	2	25	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 7	1934.91	2	2	25	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving bouts, day 7	10466.92	1	1	12.5	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	8847.36	1	1	12.5	0	1.00e+00	Retreg2
Locomotion velocity, session 8	1892.98	1	1	12.5	0	1.00e+00	Retreg2
Locomotion distance, session 8	673.32	1	1	12.5	0	1.00e+00	Retreg2
Degree of sensitization distance	7696.03	2	2	25	0	1.00e+00	Mst1 Retreg2
Degree of sensitization stereotypy	8496.38	1	1	12.5	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	4120.78	1	1	12.5	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	1097.66	1	1	12.5	0	1.00e+00	Retreg2
Condit. Reinf. active responses	11664.93	1	1	12.5	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	19375.3	1	1	12.5	0	1.00e+00	Retreg2
Incentive salience index mean	7398.25	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. lever presses	10735.09	2	2	25	0	1.00e+00	Mst1 Retreg2
Time in familiar zone, hab. session 1	41873.03	1	1	12.5	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	17770.84	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 1	1818.53	1	1	12.5	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	1687	1	1	12.5	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	1131.06	1	1	12.5	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	11707.23	2	2	25	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 2	12499.19	2	2	25	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 2	280.53	1	1	12.5	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 2	96.8	1	1	12.5	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 2	145.53	1	1	12.5	0	1.00e+00	Retreg2
Novel to familiar place preference ratio	27762.34	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Novelty place preference	27201.76	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Time in novel zone, NPP test	20429.72	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Total zone transitions, NPP test	8230.03	1	1	12.5	0	1.00e+00	Retreg2
Total locomotion distance, NPP test	7114	1	1	12.5	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	4041.22	1	1	12.5	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	1120.34	2	2	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. change in total contacts	4539.35	1	1	12.5	0	1.00e+00	Retreg2
Pavlov. Cond. index score	899.58	2	2	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	935.96	2	2	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever contacts	1539.83	2	2	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry number	2162.19	1	1	12.5	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	277.69	2	2	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	979.4	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	1310.66	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Bone: apparent density	22268.03	1	1	12.5	0	1.00e+00	Retreg2
Bone surface	12570.47	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone volume	16919.6	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Bone: connectivity density	7098.55	1	1	12.5	0	1.00e+00	Retreg2
Bone: cortical apparent density	45266.32	1	1	12.5	0	1.00e+00	Retreg2
Bone: cortical area	9496.01	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: cortical porosity	1837.29	1	1	12.5	0	1.00e+00	Retreg2
Bone: cortical porosity	4807.78	1	1	12.5	0	1.00e+00	Retreg2
Bone: cortical thickness	845.62	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: cortical thickness	6116.53	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: cortical tissue density	48453.42	1	1	12.5	0	1.00e+00	Retreg2
Bone: elastic displacement	29626.25	1	1	12.5	0	1.00e+00	Retreg2
Bone: elastic work	757.88	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: endosteal estimation	35257.61	1	1	12.5	0	1.00e+00	Retreg2
Bone: endosteal perimeter	22351.85	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Bone: final force	3544.85	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: final moment	548.75	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: marrow area	18537.14	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Bone: maximum diameter	12223.36	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: maximum force	17305.93	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: maximum moment	12386.14	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: minimum diameter	8606.13	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: periosteal estimation	19111.51	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: periosteal perimeter	21606.9	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: post-yield work	25428.45	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Bone: stiffness	17808.98	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: tissue strength	12264.67	1	1	12.5	0	1.00e+00	Retreg2
Bone: trabecular number	41138.39	1	1	12.5	0	1.00e+00	Retreg2
Bone: trabecular spacing	15656.57	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: trabecular thickness	16647.3	2	2	25	0	1.00e+00	Mst1 Retreg2
Bone: trabecular tissue density	26817.91	2	2	25	0	1.00e+00	Mst1 Retreg2
Breakpoint value in progressive ratio session	112428.06	1	1	12.5	0	1.00e+00	Retreg2
Distance traveled before self-admin	134013.73	1	1	12.5	0	1.00e+00	Retreg2
Distance traveled after self-admin	100820.36	1	1	12.5	0	1.00e+00	Retreg2
Delta time in closed arm before/after self-admin	1271.86	1	1	12.5	0	1.00e+00	Retreg2
Delta time in open arm before/after self-admin	54811.83	1	1	12.5	0	1.00e+00	Retreg2
Diff in mean of infusions in LGA sessions	54252.87	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Extinction: sum of active levers before priming	45807.86	2	2	25	0	1.00e+00	Mst1 Retreg2
Active lever presses in extinction session 6	1571.88	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Delta distance traveled before/after self-admin	12434.77	1	1	12.5	0	1.00e+00	Retreg2
Delta ambulatory time before/after self-admin	96034.01	1	1	12.5	0	1.00e+00	Retreg2
Time in closed arm before self-admin	44133.6	2	2	25	0	1.00e+00	Mst1 Retreg2
Time in closed arm after self-admin	9759.54	2	2	25	0	1.00e+00	Mst1 Retreg2
Time in open arm before self-admin	34587.99	1	1	12.5	0	1.00e+00	Retreg2
Time in open arm after self-admin	979.73	2	2	25	0	1.00e+00	Mst1 Retreg2
Sum of active levers in priming session hrs 5-6	3877.89	1	1	12.5	0	1.00e+00	Retreg2
Time to tail flick, vehicle, before self-admin	25677.46	2	1	12.5	0	1.00e+00	Mst1 Retreg2
Time to tail flick, vehicle, after self-admin	118286.85	1	1	12.5	0	1.00e+00	Retreg2
Time to tail flick, test, before self-admin	32803.11	1	1	12.5	0	1.00e+00	Retreg2
Time to tail flick, test, after self-admin	5828.87	1	1	12.5	0	1.00e+00	Retreg2
Delta time to tail flick, vehicle, before/after SA	18281.67	2	2	25	0	1.00e+00	Mst1 Retreg2
Delta time to tail flick, test, before/after SA	56832.34	1	1	12.5	0	1.00e+00	Retreg2
Ambulatory time before self-admin	171079.71	1	1	12.5	0	1.00e+00	Retreg2
Ambulatory time after self-admin	88230.17	1	1	12.5	0	1.00e+00	Retreg2
Total heroin consumption	961.5	1	1	12.5	0	1.00e+00	Retreg2
Area under the delay curve	81605.23	1	1	12.5	0	1.00e+00	Retreg2
Delay disc. indifference point, 0s delay	9477.47	1	1	12.5	0	1.00e+00	Retreg2
Delay disc. indifference point, 16s delay	74803.61	1	1	12.5	0	1.00e+00	Retreg2
Delay disc. indifference point, 2s delay	825.84	1	1	12.5	0	1.00e+00	Retreg2
Delay disc. indifference point, 24s delay	99983.64	1	1	12.5	0	1.00e+00	Retreg2
Delay disc. indifference point, 4s delay	2525.7	1	1	12.5	0	1.00e+00	Retreg2
Delay disc. indifference point, 8s delay	101423.99	1	1	12.5	0	1.00e+00	Retreg2
Delay discount exponential model param	60214.95	1	1	12.5	0	1.00e+00	Retreg2
Delay discount hyperbolic model param	45715.54	1	1	12.5	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	150160.89	1	1	12.5	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	23481.3	1	1	12.5	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 1	49255.61	1	1	12.5	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 1	41590.88	1	1	12.5	0	1.00e+00	Retreg2
Total resting periods, locomotor time 1	11802.64	1	1	12.5	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	75951.88	1	1	12.5	0	1.00e+00	Retreg2
Distance moved, locomotor task time 1	159283.67	1	1	12.5	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 1	219061.96	1	1	12.5	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	161986.9	1	1	12.5	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 2	174298.32	1	1	12.5	0	1.00e+00	Retreg2
Total resting periods, locomotor time 2	190079.87	1	1	12.5	0	1.00e+00	Retreg2
Rest time, locomotor task time 2	83778.18	1	1	12.5	0	1.00e+00	Retreg2
Distance moved, locomotor task time 2	34268.85	1	1	12.5	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 2	138414.05	1	1	12.5	0	1.00e+00	Retreg2
Weight adjusted by age	161973.18	1	1	12.5	0	1.00e+00	Retreg2
Seeking ratio, delayed vs. immediate footshock	49395.56	1	1	12.5	0	1.00e+00	Retreg2
Locomotion in novel chamber	16301.47	1	1	12.5	0	1.00e+00	Retreg2
Locomotion in novel chamber post-restriction	154642.04	1	1	12.5	0	1.00e+00	Retreg2
Progressive ratio	157894.89	1	1	12.5	0	1.00e+00	Retreg2
Food seeking constrained by brief footshock	7338.76	1	1	12.5	0	1.00e+00	Retreg2
Seeking ratio, punishment vs. effort	118281.2	1	1	12.5	0	1.00e+00	Retreg2
Run reversals in cocaine runway, females	37174.37	1	1	12.5	0	1.00e+00	Retreg2
Run reversals in cocaine runway, males	29861.56	1	1	12.5	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway	58575.8	1	1	12.5	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, F	28379.24	1	1	12.5	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	7140.1	1	1	12.5	0	1.00e+00	Retreg2
Co content in liver	4721.74	1	1	12.5	0	1.00e+00	Retreg2
Cu content in liver	162.43	1	1	12.5	0	1.00e+00	Retreg2
Fe content in liver	5656.2	1	1	12.5	0	1.00e+00	Retreg2
K content in liver	6593.53	1	1	12.5	0	1.00e+00	Retreg2
Mg content in liver	24493.99	1	1	12.5	0	1.00e+00	Retreg2
Mn content in liver	4374.36	1	1	12.5	0	1.00e+00	Retreg2
Na content in liver	16641.94	1	1	12.5	0	1.00e+00	Retreg2
Rb content in liver	428.45	1	1	12.5	0	1.00e+00	Retreg2
Zn content in liver	15755.62	1	1	12.5	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	5	0.1	1.26
Adipose	alternative TSS	15	0.4	1.46
Adipose	gene expression	11	0.1	1.36
Adipose	isoform ratio	15	0.3	1.32
Adipose	intron excision ratio	3	0.1	1.3
Adipose	mRNA stability	8	0.2	1.38
BLA	alternative polyA	3	0.1	1.46
BLA	alternative TSS	8	0.4	1.49
BLA	gene expression	10	0.1	1.44
BLA	isoform ratio	4	0.1	1.41
BLA	intron excision ratio	3	0.1	1.34
BLA	mRNA stability	4	0.2	1.36
Brain	alternative polyA	1	0	1.32
Brain	alternative TSS	7	0.2	1.4
Brain	gene expression	8	0.1	1.37
Brain	isoform ratio	8	0.1	1.36
Brain	intron excision ratio	7	0.1	1.31
Brain	mRNA stability	9	0.2	1.39
Eye	alternative polyA	0	0	1.36
Eye	alternative TSS	0	0	1.35
Eye	gene expression	2	0.2	1.43
Eye	isoform ratio	0	0	1.24
Eye	intron excision ratio	1	0.1	1.44
Eye	mRNA stability	1	0.3	1.46
IC	alternative polyA	2	0.1	1.47
IC	alternative TSS	4	0.2	1.38
IC	gene expression	11	0.2	1.45
IC	isoform ratio	1	0	1.42
IC	intron excision ratio	3	0.1	1.36
IC	mRNA stability	2	0.1	1.32
IL	alternative polyA	0	0	1.34
IL	alternative TSS	0	0	1.34
IL	gene expression	5	0.1	1.42
IL	isoform ratio	0	0	1.31
IL	intron excision ratio	1	0.1	1.29
IL	mRNA stability	0	0	1.3
LHb	alternative polyA	0	0	1.29
LHb	alternative TSS	0	0	1.23
LHb	gene expression	1	0	1.4
LHb	isoform ratio	0	0	1.21
LHb	intron excision ratio	0	0	1.31
LHb	mRNA stability	1	0.1	1.34
Liver	alternative polyA	4	0.2	1.36
Liver	alternative TSS	8	0.3	1.46
Liver	gene expression	8	0.1	1.42
Liver	isoform ratio	10	0.3	1.38
Liver	intron excision ratio	8	0.2	1.36
Liver	mRNA stability	1	0	1.32
NAcc	alternative polyA	2	0.1	7.88
NAcc	alternative TSS	13	0.3	1.42
NAcc	gene expression	7	0.1	1.42
NAcc	isoform ratio	5	0.1	1.4
NAcc	intron excision ratio	4	0.1	1.35
NAcc	mRNA stability	7	0.2	1.39
OFC	alternative polyA	2	0.2	1.46
OFC	alternative TSS	0	0	1.32
OFC	gene expression	2	0	1.42
OFC	isoform ratio	2	0.1	1.31
OFC	intron excision ratio	0	0	1.27
OFC	mRNA stability	0	0	1.37
PL	alternative polyA	7	0.2	1.46
PL	alternative TSS	5	0.1	1.37
PL	gene expression	7	0.1	1.41
PL	isoform ratio	10	0.2	1.4
PL	intron excision ratio	6	0.1	1.36
PL	mRNA stability	5	0.1	1.37
pVTA	alternative polyA	4	0.2	1.37
pVTA	alternative TSS	9	0.4	1.39
pVTA	gene expression	6	0.1	1.38
pVTA	isoform ratio	8	0.2	1.34
pVTA	intron excision ratio	6	0.1	1.31
pVTA	mRNA stability	5	0.2	1.42
RMTg	alternative polyA	0	0	1.51
RMTg	alternative TSS	1	0.2	1.38
RMTg	gene expression	1	0	1.34
RMTg	isoform ratio	0	0	1.34
RMTg	intron excision ratio	0	0	1.54
RMTg	mRNA stability	0	0	1.31