Social time

Social time indicated by average time that the rat spent with its head in the observation port providing access to the stimulus rat while the sliding door was open in the last three 18-minute sessions for males and females [cs]

Tags: Behavior · Social reinforcement

Project: p50_david_dietz

1 locus · 1 gene with independent associations · 1 total associated gene

Significant Loci

# Chr Start pos End pos # assoc genes # joint models Best TWAS P Best GWAS P Cond GWAS P Joint genes
1 chr3 76033161 77431053 1 1 1.36e-08 4.87e-03 1.6e-05 Fnbp4

Pleiotropic Associations

Trait Chi2 ratio # genes+ # genes++ % genes++ Corr Corr P Genes
BMI with tail 1.2 1 0 0 0 1e+00 Fnbp4
BMI without tail 3.29 1 0 0 0 1e+00 Fnbp4
Epididymis fat weight 4.43 1 0 0 0 1e+00 Fnbp4
Glucose 4.21 1 0 0 0 1e+00 Fnbp4
Length without tail 4.01 1 0 0 0 1e+00 Fnbp4
Retroperitoneal fat weight 1.67 1 0 0 0 1e+00 Fnbp4
Mean time between licks in bursts 2.79 1 0 0 0 1e+00 Fnbp4
Std. dev. time between licks in bursts 10.75 1 0 0 0 1e+00 Fnbp4
Patch foraging indifference point AUC 6.71 1 0 0 0 1e+00 Fnbp4
Patch foraging total patch changes 12 sec 3.93 1 0 0 0 1e+00 Fnbp4
Patch foraging total patch changes 24 sec 9.12 1 0 0 0 1e+00 Fnbp4
Patch foraging total patch changes 6 sec 6.51 1 0 0 0 1e+00 Fnbp4
Patch foraging time to switch 0 sec 3.32 1 0 0 0 1e+00 Fnbp4
Patch foraging water rate 0 sec 3.6 1 0 0 0 1e+00 Fnbp4
Locomotor activity 3.75 1 0 0 0 1e+00 Fnbp4
Locomotor testing distance 14.46 1 0 0 0 1e+00 Fnbp4
Locomotor testing rearing 22.07 1 1 100 0 1e+00 Fnbp4
Light reinforcement 2 11.19 1 0 0 0 1e+00 Fnbp4
Reaction time mean minus median 3.12 1 0 0 0 1e+00 Fnbp4
Reaction time num false alarms 4.23 1 0 0 0 1e+00 Fnbp4
Reaction time num false alarms AUC 4.78 1 0 0 0 1e+00 Fnbp4
Reaction time false alarm rate 4.37 1 0 0 0 1e+00 Fnbp4
Social response proportion 12.32 1 0 0 0 1e+00 Fnbp4
Pavlov. Cond. magazine entry latency 3.57 1 0 0 0 1e+00 Fnbp4
Pavlov. Cond. index score 3.57 1 0 0 0 1e+00 Fnbp4
Pavlov. Cond. magazine entry number 4.67 1 0 0 0 1e+00 Fnbp4
Pavlov. Cond. lever-magazine prob. diff. 3.32 1 0 0 0 1e+00 Fnbp4
Conditioned reinforcement - actives 6.77 1 0 0 0 1e+00 Fnbp4
Intermittent access intake day 1-15 change 13.55 1 0 0 0 1e+00 Fnbp4
Intermittent access intake escalation 9.05 1 0 0 0 1e+00 Fnbp4
Intermittent access intake escalation 2 19.63 1 0 0 0 1e+00 Fnbp4
Intermitt. access day 15 inactive lever presses 13.48 1 0 0 0 1e+00 Fnbp4
Intermittent access terminal intake (last 3 days) 7.14 1 0 0 0 1e+00 Fnbp4
Intermittent access standard deviation 14.61 1 0 0 0 1e+00 Fnbp4
Incentive Sensitization - Responses 10.09 1 0 0 0 1e+00 Fnbp4
Incentive Sensitization - Breakpoint 9.99 1 0 0 0 1e+00 Fnbp4
Short access day 10 total inactive lever presses 4.44 1 0 0 0 1e+00 Fnbp4
Locomotion velocity, session 2 4.36 1 0 0 0 1e+00 Fnbp4
Locomotion distance, session 2 3.64 1 0 0 0 1e+00 Fnbp4
Stereotopy head waving duration, day 3 3.3 1 0 0 0 1e+00 Fnbp4
Locomotion distance, session 7 4.4 1 0 0 0 1e+00 Fnbp4
Degree of sensitization distance 4.58 1 0 0 0 1e+00 Fnbp4
Degree of sensitization stereotypy 8.3 1 0 0 0 1e+00 Fnbp4
Condit. Reinf. inactive responses 4.32 1 0 0 0 1e+00 Fnbp4
Condit. Reinf. lever presses 3.49 1 0 0 0 1e+00 Fnbp4
Time in novel zone, hab. session 2 4.37 1 0 0 0 1e+00 Fnbp4
Total zone transitions, hab. session 2 5.02 1 0 0 0 1e+00 Fnbp4
Total locomotion distance, hab. session 2 5.36 1 0 0 0 1e+00 Fnbp4
Locomotion velocity, hab. session 2 5.82 1 0 0 0 1e+00 Fnbp4
Total locomotion distance, NPP test 4.42 1 0 0 0 1e+00 Fnbp4
Locomotion velocity, NPP test 4.11 1 0 0 0 1e+00 Fnbp4
Pavlov. Cond. magazine entry latency 3.19 1 0 0 0 1e+00 Fnbp4
Pavlov. Cond. lever-magazine prob. diff. 3.8 1 0 0 0 1e+00 Fnbp4
Bone: final force 2.69 1 0 0 0 1e+00 Fnbp4
Bone: final moment 3.21 1 0 0 0 1e+00 Fnbp4
Bone: trabecular tissue density 2.81 1 0 0 0 1e+00 Fnbp4
Total resting periods, locomotor time 1 3.54 1 0 0 0 1e+00 Fnbp4
Rest time, locomotor task time 1 8.96 1 0 0 0 1e+00 Fnbp4
Distance moved, locomotor task time 1 19.62 1 0 0 0 1e+00 Fnbp4
Rest time, locomotor task time 2 11.32 1 0 0 0 1e+00 Fnbp4
Distance moved, locomotor task time 2 9.26 1 0 0 0 1e+00 Fnbp4
Vertical activity count, locomotor time 2 4.54 1 0 0 0 1e+00 Fnbp4
Food seeking constrained by brief footshock 5.6 1 0 0 0 1e+00 Fnbp4
Latency to leave start box in cocaine runway, F 6.4 1 0 0 0 1e+00 Fnbp4
Co content in liver 3.71 1 0 0 0 1e+00 Fnbp4

Associations by panel

Tissue RNA modality # hits % hits/tests Avg chisq
Adipose alternative polyA 0 0 1.27
Adipose alternative TSS 0 0 1.3
Adipose gene expression 0 0 1.26
Adipose isoform ratio 1 0 1.35
Adipose intron excision ratio 0 0 1.46
Adipose mRNA stability 0 0 1.29
BLA alternative polyA 0 0 1.33
BLA alternative TSS 0 0 1.29
BLA gene expression 0 0 1.33
BLA isoform ratio 0 0 1.3
BLA intron excision ratio 0 0 1.41
BLA mRNA stability 0 0 1.29
Brain alternative polyA 0 0 1.35
Brain alternative TSS 0 0 1.29
Brain gene expression 0 0 1.3
Brain isoform ratio 0 0 1.32
Brain intron excision ratio 0 0 1.4
Brain mRNA stability 0 0 1.31
Eye alternative polyA 0 0 1.71
Eye alternative TSS 0 0 1.51
Eye gene expression 0 0 1.39
Eye isoform ratio 0 0 1.32
Eye intron excision ratio 0 0 1.53
Eye mRNA stability 0 0 1.56
IL alternative polyA 0 0 1.46
IL alternative TSS 0 0 1.27
IL gene expression 0 0 1.35
IL isoform ratio 0 0 1.37
IL intron excision ratio 0 0 1.26
IL mRNA stability 0 0 1.25
LHb alternative polyA 0 0 1.26
LHb alternative TSS 0 0 1.35
LHb gene expression 0 0 1.32
LHb isoform ratio 0 0 1.31
LHb intron excision ratio 0 0 1.5
LHb mRNA stability 0 0 1.29
Liver alternative polyA 0 0 1.34
Liver alternative TSS 0 0 1.26
Liver gene expression 0 0 1.27
Liver isoform ratio 0 0 1.3
Liver intron excision ratio 0 0 1.38
Liver mRNA stability 0 0 1.27
NAcc alternative polyA 0 0 1.36
NAcc alternative TSS 0 0 1.29
NAcc gene expression 0 0 1.32
NAcc isoform ratio 0 0 1.3
NAcc intron excision ratio 0 0 1.32
NAcc mRNA stability 0 0 1.3
OFC alternative polyA 0 0 1.42
OFC alternative TSS 0 0 1.2
OFC gene expression 0 0 1.31
OFC isoform ratio 0 0 1.35
OFC intron excision ratio 0 0 1.37
OFC mRNA stability 0 0 1.35
PL alternative polyA 0 0 1.35
PL alternative TSS 0 0 1.25
PL gene expression 0 0 1.3
PL isoform ratio 0 0 1.31
PL intron excision ratio 0 0 1.31
PL mRNA stability 0 0 1.32
pVTA alternative polyA 0 0 1.34
pVTA alternative TSS 0 0 1.24
pVTA gene expression 0 0 1.36
pVTA isoform ratio 0 0 1.28
pVTA intron excision ratio 0 0 1.37
pVTA mRNA stability 0 0 1.37
RMTg alternative polyA 0 0 1.44
RMTg alternative TSS 0 0 1.23
RMTg gene expression 0 0 1.4
RMTg isoform ratio 0 0 1.33
RMTg intron excision ratio 0 0 1.6
RMTg mRNA stability 0 0 1.4