Hub : Genes

P2ry2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression P2ry2 0.04 0.03 9.7e-04 0.03 0.02 0.01 0.02 8.1e-04 1.6e-03 1.0e-02 1.3e-03
2 Adipose mRNA stability P2ry2 0.12 0.06 4.1e-12 0.09 0.09 0.09 0.09 6.2e-10 1.5e-10 1.1e-09 4.9e-10
3 Eye gene expression P2ry2 0.48 0.21 2.9e-03 0.04 0 -0.01 0.04 8.4e-02 2.7e-01 4.6e-01 9.3e-02
4 IC gene expression P2ry2 0.1 0.07 4.1e-03 0.03 0.05 0.05 0.04 2.9e-02 3.5e-03 4.6e-03 5.5e-03
5 pVTA gene expression P2ry2 0.13 0.08 1.9e-07 0.08 0.09 0.1 0.1 1.0e-06 7.4e-08 2.7e-08 4.5e-08
6 NAcc gene expression P2ry2 0.1 0.05 1.1e-10 0.07 0.07 0.06 0.08 2.3e-11 1.7e-11 5.5e-10 1.5e-11
7 Brain gene expression P2ry2 0.16 0.08 4.5e-13 0.16 0.13 0.15 0.15 7.5e-15 5.4e-12 7.9e-14 5.2e-14
8 BLA gene expression P2ry2 0.12 0.07 7.9e-05 0.04 0.07 0.06 0.06 2.6e-03 1.4e-04 6.7e-04 4.1e-04
9 Liver mRNA stability P2ry2 0.03 0.02 4.7e-03 0 0.01 0.01 0 1.2e-01 1.3e-02 2.2e-02 7.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.30.60.9-0.6-0.80.6-0.90.8-0.90.8-0.5-0.6
Area under the delay curve0.10.10.5-0.7-0.1-0.10.0-0.30.2-0.10.40.4
BMI with tail0.62.14.5-0.60.6-0.41.2-0.92.1-2.12.01.7
BMI without tail0.84.08.01.31.8-1.42.2-1.62.8-2.61.91.9
Body weight1.46.110.01.11.9-1.42.5-2.83.2-2.82.82.8
Weight adjusted by age0.20.61.10.70.7-0.60.8-0.91.1-1.00.70.7
Bone surface0.30.61.21.11.0-1.00.9-0.70.5-0.7-0.3-0.2
Bone volume0.10.30.60.70.7-0.70.6-0.50.2-0.4-0.2-0.1
Breakpoint value in progressive ratio session0.71.22.2-0.9-1.41.5-1.41.1-1.40.9-0.5-0.5
Number of licking bursts0.72.25.2-2.3-2.01.6-1.40.1-0.10.21.81.6
Context. condit. distance diff. score1.31.65.52.41.3-1.40.80.4-0.30.2-1.6-1.4
Locomotion velocity, session 11.31.53.0-0.9-1.10.9-1.31.7-1.31.4-0.9-1.1
Locomotion distance, session 10.50.61.60.60.5-0.40.11.0-0.50.6-1.3-1.3
Locomotion velocity, session 20.10.10.20.20.3-0.50.30.40.3-0.1-0.0-0.1
Locomotion distance, session 20.20.30.80.30.5-0.90.30.7-0.00.0-0.7-0.6
Locomotion velocity, session 30.50.61.61.10.40.4-0.00.6-0.70.4-1.3-1.1
Locomotion distance, session 30.91.02.91.00.3-0.2-0.21.0-1.00.6-1.7-1.6
Stereotopy head waving bouts, day 30.40.51.4-0.10.10.20.3-0.90.6-0.61.11.2
Stereotopy head waving duration, day 30.10.10.30.60.3-0.00.10.2-0.20.2-0.4-0.4
Locomotion velocity, session 70.40.41.1-0.3-0.70.0-0.81.1-0.80.4-0.4-0.5
Locomotion distance, session 70.10.10.4-0.4-0.4-0.6-0.30.1-0.1-0.20.30.3
Stereotopy head waving bouts, day 71.41.65.42.31.5-0.80.90.1-0.20.3-1.7-1.4
Stereotopy head waving duration, day 71.31.65.32.31.8-0.91.2-0.10.3-0.1-1.4-1.2
Locomotion velocity, session 80.50.62.71.71.0-0.70.7-0.1-0.0-0.0-0.8-0.6
Locomotion distance, session 81.21.74.72.21.7-1.61.10.30.1-0.3-1.4-1.2
Degree of sensitization distance2.12.25.0-0.20.4-1.01.0-1.81.6-1.62.22.2
Degree of sensitization stereotypy2.52.89.33.12.1-1.31.4-0.10.1-0.0-2.0-1.8
Conditioned locomotion0.30.31.2-0.4-0.41.1-0.4-0.0-0.90.3-0.4-0.2
Cocaine response after cond. corrected0.71.02.1-1.5-1.01.2-0.5-0.30.4-0.21.51.3
Cocaine response after cond. not corrected0.20.31.1-1.1-0.70.8-0.50.30.10.10.60.3
Cocaine response before conditioning1.11.43.81.20.6-0.40.11.2-0.80.9-1.9-2.0
Saline control response1.62.24.01.92.0-1.71.8-1.61.1-1.3-0.00.3
Bone: connectivity density0.61.02.1-0.4-0.80.5-1.01.5-1.01.2-1.0-1.2
Bone: cortical apparent density0.71.12.1-1.4-1.21.3-0.7-0.40.1-0.21.41.3
Bone: cortical area0.40.61.20.50.8-0.30.9-1.00.8-1.10.60.7
Bone: cortical porosity0.50.51.70.20.10.4-0.30.5-0.90.4-1.3-1.2
Bone: cortical porosity0.50.51.80.30.20.3-0.20.4-0.80.4-1.4-1.3
Bone: cortical thickness0.30.51.6-1.0-0.81.2-0.80.6-0.60.50.10.0
Bone: cortical thickness0.00.00.10.30.3-0.00.2-0.1-0.20.1-0.3-0.2
Bone: cortical tissue density0.61.02.2-1.5-1.31.3-0.8-0.3-0.1-0.11.31.2
Condit. Reinf. active minus inactive responses0.80.91.80.90.9-0.81.0-1.31.0-1.00.70.9
Condit. Reinf. active-inactive response ratio1.51.62.81.21.2-1.41.4-1.71.3-1.30.70.9
Condit. Reinf. active responses0.30.40.90.20.5-0.30.6-1.00.5-0.60.60.7
Condit. Reinf. inactive responses0.10.20.7-0.8-0.30.5-0.30.3-0.30.4-0.1-0.1
Incentive salience index mean0.60.81.30.50.9-1.01.0-1.10.9-1.10.60.7
Condit. Reinf. lever presses0.10.20.8-0.10.5-0.90.5-0.10.4-0.4-0.00.0
Condit. Reinf. active minus inactive responses4.97.514.33.73.6-3.83.3-2.22.3-2.2-0.20.2
Condit. Reinf. active-inactive response ratio0.71.12.51.51.4-1.61.2-0.60.8-1.0-0.3-0.2
Condit. Reinf. active responses8.111.622.14.34.5-4.74.2-2.93.0-2.80.10.6
Condit. Reinf. inactive responses4.46.511.42.93.4-3.43.3-2.42.3-2.30.40.8
Condit. Reinf. lever presses10.415.132.25.25.5-5.74.8-2.42.9-2.9-1.1-0.6
Condit. Reinf. lever reinforcers received8.812.424.24.44.7-4.94.4-2.93.0-2.9-0.10.4
Conditioned reinforcement - actives0.20.72.10.60.7-0.50.30.5-0.50.6-1.4-1.4
Conditioned reinforcement - inactives0.10.20.7-0.8-0.50.6-0.4-0.0-0.30.6-0.00.0
Conditioned locomotion1.31.95.80.60.6-0.8-0.11.5-1.11.1-2.4-2.4
Patch foraging indifference point 0 sec0.71.84.41.82.1-1.61.7-0.70.7-0.6-1.1-0.9
Patch foraging indifference point AUC0.41.11.70.60.8-0.61.0-1.11.3-1.31.11.2
Delay disc. indifference point, 0s delay0.80.91.81.01.4-1.41.2-0.60.8-0.9-0.10.1
Delay disc. indifference point, 16s delay0.10.10.2-0.3-0.40.3-0.3-0.3-0.30.50.00.1
Delay disc. indifference point, 2s delay1.01.12.00.71.3-1.41.3-1.01.2-1.10.50.7
Delay disc. indifference point, 24s delay0.50.82.2-1.2-1.21.5-0.9-0.0-0.70.80.40.4
Delay disc. indifference point, 4s delay2.02.13.11.01.6-1.41.8-1.51.6-1.70.91.1
Delay disc. indifference point, 8s delay0.00.10.5-0.7-0.2-0.1-0.1-0.00.0-0.10.10.1
Indifference point function ln k0.51.64.40.60.1-0.1-0.41.2-1.41.6-2.1-2.0
Indifference point function log k0.51.64.40.60.1-0.1-0.41.2-1.41.6-2.1-2.0
Patch foraging total patch changes 0 sec0.51.63.91.62.0-1.61.6-0.70.8-0.7-0.9-0.7
Patch foraging total patch changes 12 sec1.72.33.81.31.6-1.11.8-1.71.7-2.01.01.1
Patch foraging total patch changes 18 sec0.81.83.41.41.8-1.81.7-1.11.4-1.3-0.00.1
Patch foraging total patch changes 24 sec0.72.43.41.41.6-1.61.8-1.71.7-1.80.91.0
Patch foraging total patch changes 6 sec0.20.31.01.00.9-0.50.7-0.30.4-0.6-0.3-0.2
Patch foraging time to switch 0 sec0.83.06.3-2.5-2.52.4-2.21.1-1.31.10.50.3
Patch foraging water rate 0 sec0.52.04.42.12.0-1.91.6-0.60.6-0.6-1.0-0.8
Patch foraging water rate 12 sec0.31.01.91.31.2-1.10.80.7-0.10.1-1.4-1.3
Patch foraging water rate 18 sec0.71.64.02.01.7-1.91.5-0.50.9-0.9-0.2-0.1
Patch foraging water rate 24 sec0.71.02.70.40.4-0.0-0.11.0-0.91.1-1.6-1.6
Patch foraging water rate 6 sec0.40.61.50.80.8-1.20.50.5-0.3-0.0-1.1-1.1
Seeking ratio, delayed vs. immediate footshock1.11.52.7-1.6-1.61.6-1.61.0-1.00.8-0.3-0.6
Distance traveled before self-admin0.20.40.9-0.7-0.90.7-0.70.3-0.3-0.00.70.6
Distance traveled after self-admin1.22.13.6-0.3-1.31.2-1.61.9-1.91.5-1.3-1.3
Extensor digitorum longus weight0.41.43.5-0.50.2-0.30.7-1.11.7-1.21.91.7
Bone: elastic displacement2.22.84.2-1.7-2.02.0-2.01.8-1.61.9-0.4-0.6
Bone: elastic work3.14.06.0-2.1-2.42.5-2.42.3-1.82.1-0.6-1.0
Bone: endosteal estimation1.84.46.01.92.3-2.42.4-2.42.3-2.41.11.2
Bone: endosteal perimeter1.94.76.72.12.5-2.52.6-2.22.3-2.50.81.0
Epididymis fat weight0.10.51.1-1.1-0.90.9-0.6-0.10.30.01.00.8
Delta time in closed arm before/after self-admin1.61.54.4-1.1-0.50.40.1-1.21.1-1.02.11.9
Delta time in open arm before/after self-admin1.71.94.52.12.0-1.81.7-1.01.0-0.9-0.5-0.2
Diff in mean of infusions in LGA sessions1.01.84.6-1.5-1.92.1-1.50.1-0.90.50.90.9
Delay discount exponential model param0.10.10.50.70.10.0-0.00.2-0.20.2-0.4-0.4
Extinction: sum of active levers before priming0.10.10.20.40.4-0.10.4-0.30.3-0.20.20.3
Active lever presses in extinction session 62.92.97.40.4-0.1-0.3-0.92.0-2.01.7-2.7-2.6
Bone: final force0.10.20.4-0.6-0.20.6-0.1-0.6-0.2-0.40.30.4
Bone: final moment0.10.10.4-0.4-0.00.30.1-0.7-0.1-0.60.20.4
Food consumed during 24 hour testing period0.91.83.81.91.7-1.81.10.30.00.0-1.7-1.6
Glucose0.00.00.30.0-0.10.5-0.10.30.0-0.20.0-0.1
Heart weight0.30.51.91.41.0-0.50.7-0.20.1-0.2-0.8-0.6
Delay discount hyperbolic model param0.20.20.40.6-0.10.3-0.30.4-0.50.4-0.6-0.6
Intermittent access intake day 1-15 change0.10.51.60.40.4-0.50.01.3-0.30.6-1.0-1.1
Intermittent access intake escalation0.10.61.60.60.5-0.50.11.3-0.40.6-1.2-1.2
Intermittent access intake escalation 20.10.20.50.20.6-0.70.40.30.3-0.2-0.4-0.5
Intermitt. access day 1 inactive lever presses0.10.72.5-1.6-0.90.7-0.6-0.20.10.01.00.9
Intermitt. access day 15 inactive lever presses0.21.01.8-0.5-1.11.0-1.21.2-1.31.2-0.7-0.6
Intermitt. access escalation Index0.00.10.60.10.2-0.50.2-0.30.2-0.70.00.1
Intermittent access day 1 total infusions0.30.92.21.51.2-1.10.8-0.3-0.10.1-1.2-1.0
Intermittent access day 15 total infusions0.40.92.31.11.1-0.80.60.5-0.40.5-1.5-1.4
Intermittent access terminal intake (last 3 days)0.61.02.21.51.4-1.20.90.0-0.1-0.0-1.3-1.1
Intermittent access total infusions0.91.12.41.61.5-1.41.2-0.20.3-0.2-1.0-0.8
Intermittent access day 1 locomotion0.20.41.20.30.2-0.2-0.10.2-0.70.7-1.1-0.9
Intermittent access day 15 total locomotion0.31.33.30.20.2-0.4-0.31.4-1.11.2-1.8-1.8
Intermittent access total locomotion0.50.61.60.80.7-0.70.30.4-0.50.7-1.2-1.1
Intermittent access standard deviation0.10.30.60.10.5-0.60.6-0.10.8-0.50.60.6
Left kidney weight0.32.74.80.71.3-1.11.7-1.82.2-2.01.81.8
Right kidney weight0.74.77.61.01.8-1.82.3-2.62.7-2.42.22.2
Cocaine induced anxiety0.61.75.0-2.2-1.81.7-1.50.5-0.90.90.40.3
Post-drug Anxiety0.91.02.6-1.2-1.41.6-1.1-0.2-0.50.70.80.8
Baseline Anxiety0.60.93.31.81.1-0.81.1-1.00.7-0.50.20.4
Tail length1.910.014.53.23.1-2.53.5-3.83.6-3.02.52.9
Length with tail1.87.813.12.92.8-2.23.1-3.62.9-2.62.22.6
Length without tail0.00.20.80.40.2-0.20.3-0.90.2-0.20.60.8
Times rat made contact with spout0.50.61.4-0.30.1-0.30.4-0.90.9-0.81.21.2
Lifetime Intake1.11.43.31.81.7-1.51.2-0.20.3-0.1-1.1-0.9
Liver weight, left0.91.62.8-0.50.4-0.70.9-1.71.5-1.41.71.6
Liver weight, right1.62.86.8-0.30.1-0.10.8-2.21.9-1.82.62.6
Locomotor activity0.20.30.80.90.7-0.50.50.0-0.1-0.1-0.5-0.4
Locomotor testing distance0.71.83.51.81.9-1.61.7-1.11.0-1.4-0.00.2
Locomotor testing rearing0.51.92.71.31.5-1.21.6-1.61.3-1.60.91.1
Locomotion in novel chamber0.71.02.1-1.0-0.5-0.0-0.71.2-1.01.0-1.3-1.5
Locomotion in novel chamber post-restriction0.31.02.31.11.1-1.30.60.5-0.20.0-1.5-1.5
Fecal boli incidents, locomotor time 10.30.92.0-1.4-0.3-0.6-0.51.0-0.60.6-1.2-1.4
Change in fecal boli incidents, locomotor task0.20.20.50.6-0.30.6-0.1-0.60.10.10.70.7
Time >=10cm from walls, locomotor time 10.50.61.50.80.9-0.90.5-0.2-0.30.1-1.2-1.1
Bouts of movement, locomotor time 10.10.10.20.20.4-0.40.3-0.30.0-0.2-0.3-0.2
Total resting periods, locomotor time 10.20.20.6-0.2-0.1-0.1-0.30.3-0.60.4-0.8-0.7
Rest time, locomotor task time 10.40.61.20.2-0.60.3-0.80.5-1.11.0-1.0-0.9
Distance moved, locomotor task time 10.30.92.0-0.00.6-0.20.9-0.81.2-1.41.21.1
Vertical activity count, locomotor time 10.10.81.50.10.9-0.71.0-0.91.1-1.20.80.8
Time >=10cm from walls, locomotor time 20.61.74.12.01.8-1.21.7-1.70.8-0.7-0.10.2
Bouts of movement, locomotor time 20.61.94.60.71.2-0.41.5-2.11.5-1.61.31.4
Total resting periods, locomotor time 20.31.33.20.20.7-0.11.0-1.81.2-1.31.21.3
Rest time, locomotor task time 21.01.63.7-1.7-1.91.6-1.71.0-0.91.00.40.2
Distance moved, locomotor task time 21.62.14.71.82.2-1.32.0-1.31.2-1.4-0.10.1
Vertical activity count, locomotor time 20.51.12.20.91.4-1.01.5-1.21.1-1.00.40.6
Light reinforcement 10.52.35.7-2.1-2.12.4-1.71.0-0.60.91.00.7
Light reinforcement 20.51.23.3-0.8-1.01.1-1.11.8-0.91.2-0.6-0.9
Bone: marrow area1.74.15.71.72.1-2.22.3-2.32.3-2.41.11.3
Bone: maximum diameter1.53.04.92.12.2-1.42.2-1.81.7-2.00.50.7
Bone: maximum force0.00.10.2-0.3-0.10.4-0.1-0.4-0.2-0.30.10.2
Bone: maximum moment0.00.10.2-0.00.10.20.1-0.40.0-0.50.10.1
Mean time between licks in bursts1.38.112.42.73.4-2.53.5-3.43.0-3.11.41.8
Mean num. licks in bursts0.72.04.52.12.0-1.71.4-0.40.3-0.4-1.5-1.2
Cd content in liver0.40.41.0-0.20.00.10.3-0.90.7-0.71.01.0
Co content in liver1.82.13.11.61.7-1.71.8-1.81.4-1.30.50.7
Cu content in liver2.02.43.70.81.4-1.41.7-1.91.9-1.81.31.4
Fe content in liver0.00.00.0-0.1-0.10.1-0.1-0.0-0.10.1-0.00.0
K content in liver0.30.30.7-0.60.1-0.10.3-0.50.6-0.50.80.8
Mg content in liver0.00.00.1-0.10.3-0.40.30.10.2-0.2-0.0-0.0
Mn content in liver2.12.33.2-1.4-1.71.6-1.81.8-1.61.6-0.8-1.0
Na content in liver0.30.31.01.00.8-0.70.50.20.10.0-0.6-0.5
Rb content in liver0.20.20.50.40.7-0.60.6-0.50.3-0.3-0.3-0.2
Se content in liver3.64.27.5-2.7-2.72.7-2.51.6-1.81.90.0-0.2
Sr content in liver0.50.51.50.4-0.20.2-0.41.2-0.60.7-0.8-1.0
Zn content in liver1.92.24.61.62.0-2.11.9-0.91.5-1.40.10.2
Bone: minimum diameter2.24.26.81.21.8-1.32.2-2.62.4-2.51.92.1
Time in familiar zone, hab. session 10.20.20.30.50.4-0.40.5-0.50.6-0.40.50.5
Time in novel zone, hab. session 10.10.20.3-0.5-0.50.5-0.4-0.2-0.10.40.30.3
Total zone transitions, hab. session 10.50.71.20.3-0.30.6-0.61.1-1.01.0-1.1-1.0
Total locomotion distance, hab. session 11.21.74.4-0.10.2-0.20.7-1.71.4-1.42.02.1
Locomotion velocity, hab. session 10.81.12.9-0.20.2-0.10.6-1.31.1-1.21.61.7
Time in familiar zone, hab. session 21.82.04.82.11.6-2.21.5-1.31.0-1.2-0.00.2
Time in novel zone, hab. session 21.11.22.3-1.5-1.11.5-1.11.4-0.81.0-0.3-0.5
Total zone transitions, hab. session 20.81.12.71.61.0-0.20.40.7-0.60.7-1.6-1.4
Total locomotion distance, hab. session 21.62.13.70.91.2-0.71.5-1.91.6-1.51.61.8
Locomotion velocity, hab. session 21.92.54.40.91.1-0.81.5-2.01.7-1.61.82.1
Novel to familiar place preference ratio0.20.21.10.30.50.30.5-1.0-0.0-0.00.00.3
Novelty place preference0.20.21.00.40.50.30.5-1.0-0.00.10.00.3
Time in novel zone, NPP test0.20.31.10.60.70.10.6-1.0-0.00.0-0.10.2
Total zone transitions, NPP test0.40.61.7-0.3-0.10.2-0.41.3-0.70.7-1.1-1.1
Total locomotion distance, NPP test0.71.02.8-0.60.1-0.20.5-0.81.2-1.11.71.6
Locomotion velocity, NPP test0.71.03.0-0.9-0.20.20.3-0.61.1-0.91.71.6
Intraocular pressure0.61.02.0-0.3-0.70.7-0.91.2-0.81.2-1.1-1.4
Delta distance traveled before/after self-admin1.01.13.21.50.8-0.50.20.5-0.80.7-1.8-1.6
Delta ambulatory time before/after self-admin0.71.23.61.30.6-0.50.00.7-0.80.9-1.9-1.7
Parametrial fat weight0.30.81.9-1.2-1.21.4-0.90.80.20.40.80.5
Pavlov. Cond. lever latency0.81.12.7-1.0-1.41.6-1.20.7-0.81.00.30.2
Pavlov. Cond. magazine entry latency2.43.19.32.32.3-3.02.0-0.91.3-1.3-0.5-0.3
Pavlov. Cond. change in total contacts1.11.23.11.31.5-1.81.3-1.00.8-0.8-0.3-0.1
Pavlov. Cond. index score1.92.56.61.82.1-2.61.9-0.91.3-1.3-0.4-0.2
Pavlov. Cond. latency score1.82.36.01.72.0-2.41.8-1.01.2-1.4-0.4-0.2
Pavlov. Cond. lever contacts0.91.12.51.21.4-1.61.2-0.70.9-1.0-0.2-0.1
Pavlov. Cond. magazine entry number2.43.08.4-2.1-2.32.9-2.01.0-1.31.30.50.3
Pavlov. Cond. intertrial magazine entries0.70.82.7-1.2-1.11.6-1.00.4-0.80.40.10.1
Pavlov. Cond. lever-magazine prob. diff.1.62.05.61.61.9-2.41.6-0.81.1-1.1-0.4-0.3
Pavlov. Cond. response bias1.11.44.51.51.5-2.11.4-0.60.9-0.8-0.3-0.2
Pavlov. Cond. lever latency10.114.230.0-5.5-5.45.2-4.61.8-2.52.71.61.1
Pavlov. Cond. magazine entry latency1.62.35.42.22.0-2.31.50.50.4-0.6-1.5-1.3
Pavlov. Cond. change in total contacts4.511.026.85.24.8-4.44.0-1.42.0-2.0-1.6-1.1
Pavlov. Cond. index score6.29.820.74.54.5-4.43.8-1.22.0-2.1-1.5-1.1
Pavlov. Cond. latency score5.18.217.44.24.2-4.03.4-0.91.8-1.8-1.5-1.2
Pavlov. Cond. lever contacts9.113.528.55.35.3-5.04.5-1.92.5-2.6-1.5-0.9
Pavlov. Cond. magazine entry number3.24.29.6-3.1-2.83.0-2.1-0.2-0.70.61.81.6
Pavlov. Cond. intertrial magazine entries0.81.83.90.61.0-0.41.3-2.01.6-1.61.51.6
Pavlov. Cond. lever-magazine prob. diff.6.29.519.84.44.5-4.43.8-1.32.1-2.1-1.3-0.9
Pavlov. Cond. response bias9.713.428.15.35.2-5.34.4-1.42.3-2.5-1.8-1.3
Time in closed arm before self-admin0.91.64.31.80.8-0.60.10.8-1.11.0-2.1-1.8
Time in closed arm after self-admin0.80.91.6-0.8-1.31.1-1.20.7-1.21.1-0.4-0.4
Time in open arm before self-admin2.12.57.8-2.8-2.21.9-1.70.9-0.30.41.30.8
Time in open arm after self-admin0.60.61.40.40.6-0.60.8-0.71.2-0.90.80.8
Bone: periosteal estimation1.33.04.61.41.9-1.62.1-1.92.0-2.10.91.1
Bone: periosteal perimeter1.32.64.11.51.9-1.62.0-1.51.8-2.00.80.9
Bone: post-yield work0.10.10.40.60.3-0.30.3-0.40.3-0.20.10.2
Progressive ratio test 1 active lever presses0.30.41.10.2-0.2-0.0-0.50.6-0.81.1-0.9-0.8
Progressive ratio test 1 breakpoint0.20.41.00.2-0.2-0.0-0.40.6-0.81.0-0.8-0.8
Progressive ratio test 1 inactive lever presses0.10.40.9-0.4-0.30.2-0.50.5-0.71.0-0.7-0.7
Progressive ratio test 2 active lever presses0.20.20.70.60.8-0.50.7-0.20.20.0-0.3-0.3
Progressive ratio test 2 breakpoint0.20.20.70.70.8-0.60.7-0.20.20.0-0.4-0.3
Progressive ratio test 2 inactive lever presses0.20.51.10.30.2-0.1-0.10.7-0.71.0-1.0-1.0
Incentive Sensitization - Responses0.20.51.40.81.2-0.71.1-0.60.6-0.6-0.00.1
Incentive Sensitization - Breakpoint0.20.41.20.71.1-0.61.0-0.40.5-0.4-0.1-0.1
Sum of active levers in priming session hrs 5-60.20.20.40.3-0.10.3-0.30.5-0.70.4-0.5-0.4
Progressive ratio0.20.51.10.50.2-0.8-0.11.0-0.40.3-1.0-1.0
Food seeking constrained by brief footshock1.62.03.11.71.7-1.61.7-1.21.5-1.50.60.7
Seeking ratio, punishment vs. effort1.12.43.71.01.4-0.81.7-1.91.9-1.71.51.7
Retroperitoneal fat weight1.35.817.9-1.7-0.90.70.3-2.02.4-2.04.24.0
Reaction time number correct0.41.32.30.0-0.41.2-0.81.2-1.51.4-1.4-1.3
Reaction time mean minus median0.21.01.80.81.2-1.31.2-1.00.9-1.10.30.4
Reaction time mean minus median AUC0.10.61.30.91.1-1.11.0-0.50.4-0.6-0.4-0.3
Reaction time num false alarms0.81.43.9-2.0-1.21.0-0.6-0.70.2-0.31.61.5
Reaction time num false alarms AUC0.40.93.8-2.0-1.10.8-0.6-0.40.0-0.11.00.9
Reaction time trials correct on left0.41.32.30.0-0.41.2-0.81.2-1.51.4-1.4-1.3
Reaction time trials on left0.41.32.3-0.0-0.51.1-0.81.3-1.51.4-1.4-1.3
Reaction time mean0.30.81.9-1.2-0.40.2-0.0-0.90.5-0.61.41.4
Reaction time mean AUC0.30.61.8-1.3-0.70.5-0.3-0.60.1-0.21.11.1
Median of all reaction times0.60.92.9-1.7-1.00.6-0.5-0.50.1-0.21.31.3
Reaction time omissions0.20.40.8-0.50.1-0.40.3-0.70.7-0.60.90.9
Reaction time false alarm rate0.91.33.7-1.9-0.90.3-0.3-0.80.7-0.71.71.5
Reaction time premature initiation rate2.94.67.01.82.1-2.22.4-2.22.5-2.61.51.6
Reaction time premature initiations0.61.72.71.41.6-1.41.6-1.11.4-1.60.50.5
Std. dev. reaction times0.62.03.50.21.1-1.21.4-1.91.6-1.71.51.6
Reaction time trials completed0.41.32.3-0.0-0.51.1-0.81.3-1.51.4-1.4-1.3
Reaction time trials AUC0.20.91.60.1-0.31.0-0.61.0-1.31.1-1.2-1.1
Run reversals in cocaine runway, females2.93.36.10.60.9-0.91.5-1.92.2-2.22.52.5
Run reversals in cocaine runway, males0.20.20.5-0.6-0.5-0.2-0.60.5-0.50.7-0.3-0.4
Latency to leave start box in cocaine runway0.91.33.5-1.0-1.21.3-0.6-0.30.5-0.41.91.7
Latency to leave start box in cocaine runway, F1.51.95.8-0.8-0.81.1-0.0-1.11.2-1.22.42.3
Latency to leave start box in cocaine runway, M0.50.51.0-0.8-0.90.5-0.91.0-0.50.6-0.2-0.4
Std. dev. time between licks in bursts2.44.56.61.42.0-1.72.4-2.52.5-2.61.82.0
Total sessions with >9 infusions1.41.84.42.11.9-1.91.5-0.50.7-0.3-0.9-0.7
Short access day 1 total inactive lever presses0.00.00.20.10.4-0.20.3-0.20.10.1-0.1-0.1
Short access day 10 total inactive lever presses0.10.62.3-1.5-1.00.6-0.90.3-0.50.40.20.2
Short access day 1 total infusions1.53.06.32.32.5-2.22.2-1.31.3-1.2-0.4-0.2
Short access day 10 total infusions0.91.53.41.81.7-1.81.4-0.50.6-0.5-0.7-0.5
Short access total infusions1.31.84.62.21.9-1.81.5-0.40.5-0.3-1.1-0.9
Short access day 1 locomotion0.71.13.00.81.0-1.30.50.6-0.30.6-1.7-1.7
Short access day 10 total locomotion0.20.72.40.91.3-1.51.0-0.10.4-0.3-0.5-0.4
Short access total locomotion0.40.51.40.40.3-0.60.00.7-0.50.8-1.2-1.2
One hour access (0.3 mA shock)0.50.61.60.91.1-1.30.80.10.2-0.1-0.8-0.8
Compulsive drug intake2.03.04.2-1.5-1.91.8-2.11.8-1.91.9-1.2-1.4
One hour access (shock baseline)0.61.63.51.81.9-1.91.5-0.30.7-0.7-0.7-0.5
Social response proportion0.40.51.4-0.9-0.20.50.2-0.40.6-0.61.21.1
Social responses1.11.43.4-0.60.3-0.20.8-1.51.2-1.21.81.8
Social time1.72.67.1-1.7-1.92.7-1.81.2-1.41.70.10.0
Soleus weight1.33.97.9-0.50.6-0.81.4-2.22.5-2.42.82.7
Bone: stiffness0.30.61.4-0.8-0.40.5-0.0-1.10.3-0.71.11.2
Tibialis anterior weight0.31.22.30.40.8-0.81.1-1.51.3-1.11.21.2
Time to tail flick, vehicle, before self-admin0.20.20.90.90.5-0.10.30.2-0.20.1-0.6-0.4
Time to tail flick, vehicle, after self-admin0.30.61.71.31.1-0.70.8-0.20.20.1-1.0-0.9
Time to tail flick, test, before self-admin1.61.83.82.01.4-1.21.5-1.51.3-1.50.60.8
Time to tail flick, test, after self-admin1.92.03.61.21.3-1.21.5-1.91.5-1.61.11.3
Delta time to tail flick, vehicle, before/after SA0.10.20.50.10.4-0.70.4-0.10.20.0-0.5-0.6
Delta time to tail flick, test, before/after SA0.30.41.5-1.2-0.70.7-0.60.2-0.30.40.40.2
Tibia length0.61.74.61.21.4-1.50.70.3-0.80.2-2.1-1.9
Ambulatory time before self-admin0.20.71.5-0.9-1.21.1-1.10.7-0.80.50.20.1
Ambulatory time after self-admin1.62.64.60.5-0.90.9-1.41.9-2.11.9-2.0-1.9
Bone: tissue strength2.52.64.6-0.9-1.41.5-1.72.1-1.91.8-1.4-1.5
Total heroin consumption0.10.10.20.40.20.00.00.2-0.40.1-0.4-0.3
Bone: trabecular number1.01.82.8-1.4-1.61.5-1.71.5-1.31.5-0.4-0.6
Bone: trabecular spacing0.30.40.80.60.8-0.90.50.60.1-0.3-0.8-0.8
Bone: trabecular thickness0.20.30.9-0.1-0.40.6-0.1-1.0-0.0-0.20.80.9
Bone: trabecular tissue density1.32.25.8-1.1-0.40.90.3-2.01.0-1.32.32.4
Water consumed over 24 hours0.10.30.5-0.6-0.70.6-0.70.4-0.50.60.0-0.0
Number of responses in last shaping day0.60.71.6-1.0-0.1-0.00.3-1.30.8-0.61.21.2