Hub : Traits

Intermittent access standard deviation

Tags: Behavior · Intermittent access · Cocaine

Project: p50_paul_meyer_2020

1 loci · 1 genes with independent associations · 1 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	8	108584253	109479622	1	1	1.47e-09	1.8e-02	9.11e-04	Apeh

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
Liver weight, left	3.97	1	0	0	0	1e+00	Apeh
Parametrial fat weight	2.45	1	0	0	0	1e+00	Apeh
Std. dev. time between licks in bursts	6.89	1	0	0	0	1e+00	Apeh
Indifference point 0 sec	3.78	1	0	0	0	1e+00	Apeh
Delay discounting total patch changes 18 sec	5.91	1	0	0	0	1e+00	Apeh
Delay discounting total patch changes 6 sec	4.88	1	0	0	0	1e+00	Apeh
Reaction time premature initiation rate	2.91	1	0	0	0	1e+00	Apeh
Social time	3.43	1	0	0	0	1e+00	Apeh
Saline control response	4.42	1	0	0	0	1e+00	Apeh
Conditioned reinforcement - inactives	32.17	1	1	100	0	1e+00	Apeh
Conditioned locomotion	5.27	1	0	0	0	1e+00	Apeh
Intermittent access intake day 1-15 change	26.8	1	1	100	0	1e+00	Apeh
Intermittent access intake escalation	21.18	1	0	0	0	1e+00	Apeh
Intermittent access intake escalation 2	29.8	1	1	100	0	1e+00	Apeh
Intermitt. access day 15 inactive lever presses	27.39	1	1	100	0	1e+00	Apeh
Intermittent access day 15 total infusions	4.68	1	0	0	0	1e+00	Apeh
Intermittent access total locomotion	3.55	1	0	0	0	1e+00	Apeh
Cocaine induced anxiety	6.44	1	0	0	0	1e+00	Apeh
Incentive Sensitization - Responses	8.7	1	0	0	0	1e+00	Apeh
Incentive Sensitization - Breakpoint	8.81	1	0	0	0	1e+00	Apeh
Progressive ratio test 1 active lever presses	9.94	1	0	0	0	1e+00	Apeh
Progressive ratio test 1 breakpoint	10.22	1	0	0	0	1e+00	Apeh
Progressive ratio test 1 inactive lever presses	8.51	1	0	0	0	1e+00	Apeh
Progressive ratio test 2 inactive lever presses	41.52	1	1	100	0	1e+00	Apeh
Total sessions with >9 infusions	12.6	1	0	0	0	1e+00	Apeh
Short access day 1 total inactive lever presses	7.7	1	0	0	0	1e+00	Apeh
Short access day 10 total inactive lever presses	40.3	1	1	100	0	1e+00	Apeh
Short access day 10 total locomotion	6.38	1	0	0	0	1e+00	Apeh
Short access total locomotion	10.65	1	0	0	0	1e+00	Apeh
Compulsive drug intake	7.66	1	0	0	0	1e+00	Apeh
Number of responses in last shaping day	12	1	0	0	0	1e+00	Apeh
Novel to familiar place preference ratio	6.25	1	0	0	0	1e+00	Apeh
Novelty place preference	7.01	1	0	0	0	1e+00	Apeh
Time in novel zone, NPP test	6.78	1	0	0	0	1e+00	Apeh
Pavlov. Cond. lever latency	3.62	1	0	0	0	1e+00	Apeh
Pavlov. Cond. magazine entry latency	5.36	1	0	0	0	1e+00	Apeh
Pavlov. Cond. index score	4.44	1	0	0	0	1e+00	Apeh
Pavlov. Cond. latency score	4.18	1	0	0	0	1e+00	Apeh
Pavlov. Cond. magazine entry number	4.21	1	0	0	0	1e+00	Apeh
Pavlov. Cond. lever-magazine prob. diff.	4.88	1	0	0	0	1e+00	Apeh
Pavlov. Cond. response bias	5.32	1	0	0	0	1e+00	Apeh
Bone: connectivity density	3.22	1	0	0	0	1e+00	Apeh
Bone: cortical area	3.3	1	0	0	0	1e+00	Apeh
Bone: maximum diameter	2.57	1	0	0	0	1e+00	Apeh
Time to tail flick, test, before self-admin	4.01	1	0	0	0	1e+00	Apeh
Ambulatory time before self-admin	10.3	1	0	0	0	1e+00	Apeh
Cu content in liver	4.82	1	0	0	0	1e+00	Apeh

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.03
Adipose	alternative TSS	0	0	1.07
Adipose	gene expression	0	0	1.07
Adipose	isoform ratio	0	0	1.08
Adipose	intron excision ratio	0	0	1.03
Adipose	mRNA stability	0	0	1.08
BLA	alternative polyA	0	0	1.03
BLA	alternative TSS	0	0	0.99
BLA	gene expression	0	0	1.07
BLA	isoform ratio	0	0	1.05
BLA	intron excision ratio	0	0	1.1
BLA	mRNA stability	0	0	1.07
Brain	alternative polyA	0	0	1.02
Brain	alternative TSS	0	0	1.06
Brain	gene expression	0	0	1.08
Brain	isoform ratio	0	0	1.05
Brain	intron excision ratio	0	0	1.01
Brain	mRNA stability	0	0	1.05
Eye	alternative polyA	0	0	0.94
Eye	alternative TSS	0	0	1.05
Eye	gene expression	0	0	1.09
Eye	isoform ratio	0	0	1.19
Eye	intron excision ratio	0	0	1.15
Eye	mRNA stability	0	0	1.23
IL	alternative polyA	0	0	1.01
IL	alternative TSS	0	0	1.29
IL	gene expression	0	0	1.05
IL	isoform ratio	0	0	1.05
IL	intron excision ratio	0	0	1.1
IL	mRNA stability	0	0	0.96
LHb	alternative polyA	0	0	1.02
LHb	alternative TSS	0	0	1.14
LHb	gene expression	0	0	1.07
LHb	isoform ratio	0	0	1.08
LHb	intron excision ratio	0	0	1.19
LHb	mRNA stability	0	0	1.11
Liver	alternative polyA	0	0	0.97
Liver	alternative TSS	0	0	1.12
Liver	gene expression	0	0	1.09
Liver	isoform ratio	0	0	1.12
Liver	intron excision ratio	0	0	1.06
Liver	mRNA stability	0	0	1.06
NAcc	alternative polyA	0	0	1.12
NAcc	alternative TSS	0	0	1.11
NAcc	gene expression	0	0	1.08
NAcc	isoform ratio	0	0	1.08
NAcc	intron excision ratio	0	0	1.07
NAcc	mRNA stability	0	0	1.07
OFC	alternative polyA	0	0	1.1
OFC	alternative TSS	0	0	1.15
OFC	gene expression	0	0	1.06
OFC	isoform ratio	0	0	1.09
OFC	intron excision ratio	0	0	1.11
OFC	mRNA stability	0	0	1.05
PL	alternative polyA	0	0	1.14
PL	alternative TSS	0	0	1.08
PL	gene expression	0	0	1.08
PL	isoform ratio	0	0	1.08
PL	intron excision ratio	0	0	1.12
PL	mRNA stability	1	0	1.06