Patch foraging total patch changes 6 sec

Delay discounting using a sequential patch depletion procedure, total patch (feeder) changes in the last two sessions with an experimenter-imposed delay of 6 sec [n]

Tags: Behavior · Delay discounting

Project: p50_david_dietz

1 locus · 1 gene with independent associations · 1 total associated gene

Significant Loci

# Chr Start pos End pos # assoc genes # joint models Best TWAS P Best GWAS P Cond GWAS P Joint genes
1 chr9 75969545 77365260 1 1 1.45e-09 1.71e-02 1e+00 Zfand2b

Pleiotropic Associations

Trait Chi2 ratio # genes+ # genes++ % genes++ Corr Corr P Genes
BMI with tail 8.42 1 1 100 0 1e+00 Zfand2b
BMI without tail 53.65 1 1 100 0 1e+00 Zfand2b
Epididymis fat weight 111.28 1 1 100 0 1e+00 Zfand2b
Heart weight 71.7 1 1 100 0 1e+00 Zfand2b
Left kidney weight 27.22 1 1 100 0 1e+00 Zfand2b
Right kidney weight 54.05 1 1 100 0 1e+00 Zfand2b
Tail length 125.62 1 1 100 0 1e+00 Zfand2b
Length with tail 4.78 1 0 0 0 1e+00 Zfand2b
Length without tail 77.43 1 1 100 0 1e+00 Zfand2b
Liver weight, left 2.4 1 0 0 0 1e+00 Zfand2b
Liver weight, right 17.57 1 1 100 0 1e+00 Zfand2b
Parametrial fat weight 9.99 1 0 0 0 1e+00 Zfand2b
Retroperitoneal fat weight 7.53 1 0 0 0 1e+00 Zfand2b
Intraocular pressure 51.69 1 1 100 0 1e+00 Zfand2b
Tibialis anterior weight 1.65 1 0 0 0 1e+00 Zfand2b
Number of licking bursts 32.5 1 1 100 0 1e+00 Zfand2b
Food consumed during 24 hour testing period 15.78 1 0 0 0 1e+00 Zfand2b
Times rat made contact with spout 9.25 1 0 0 0 1e+00 Zfand2b
Mean time between licks in bursts 9.22 1 0 0 0 1e+00 Zfand2b
Mean num. licks in bursts 18.13 1 0 0 0 1e+00 Zfand2b
Std. dev. time between licks in bursts 12.12 1 0 0 0 1e+00 Zfand2b
Water consumed over 24 hours 34.33 1 1 100 0 1e+00 Zfand2b
Patch foraging indifference point 0 sec 11.8 1 0 0 0 1e+00 Zfand2b
Patch foraging indifference point AUC 24.2 1 1 100 0 1e+00 Zfand2b
Indifference point function ln k 54.42 1 1 100 0 1e+00 Zfand2b
Indifference point function log k 54.42 1 1 100 0 1e+00 Zfand2b
Patch foraging total patch changes 0 sec 23.48 1 1 100 0 1e+00 Zfand2b
Patch foraging total patch changes 12 sec 4.29 1 0 0 0 1e+00 Zfand2b
Patch foraging total patch changes 18 sec 48.28 1 1 100 0 1e+00 Zfand2b
Patch foraging total patch changes 24 sec 77.61 1 1 100 0 1e+00 Zfand2b
Patch foraging time to switch 0 sec 33.47 1 1 100 0 1e+00 Zfand2b
Patch foraging water rate 0 sec 39.47 1 1 100 0 1e+00 Zfand2b
Patch foraging water rate 12 sec 69.49 1 1 100 0 1e+00 Zfand2b
Patch foraging water rate 18 sec 9.71 1 0 0 0 1e+00 Zfand2b
Patch foraging water rate 24 sec 12.61 1 0 0 0 1e+00 Zfand2b
Patch foraging water rate 6 sec 35.43 1 1 100 0 1e+00 Zfand2b
Locomotor activity 12.38 1 0 0 0 1e+00 Zfand2b
Locomotor testing distance 47.2 1 1 100 0 1e+00 Zfand2b
Locomotor testing rearing 99.51 1 1 100 0 1e+00 Zfand2b
Light reinforcement 1 19.25 1 1 100 0 1e+00 Zfand2b
Light reinforcement 2 6.57 1 0 0 0 1e+00 Zfand2b
Reaction time number correct 114.79 1 1 100 0 1e+00 Zfand2b
Reaction time mean minus median 179.03 1 1 100 0 1e+00 Zfand2b
Reaction time mean minus median AUC 232.47 1 1 100 0 1e+00 Zfand2b
Reaction time num false alarms 5.7 1 0 0 0 1e+00 Zfand2b
Reaction time num false alarms AUC 27.43 1 1 100 0 1e+00 Zfand2b
Reaction time trials correct on left 114.79 1 1 100 0 1e+00 Zfand2b
Reaction time trials on left 106.69 1 1 100 0 1e+00 Zfand2b
Reaction time mean 36.11 1 1 100 0 1e+00 Zfand2b
Reaction time mean AUC 33.75 1 1 100 0 1e+00 Zfand2b
Median of all reaction times 17.65 1 0 0 0 1e+00 Zfand2b
Reaction time omissions 46.56 1 1 100 0 1e+00 Zfand2b
Reaction time false alarm rate 3.92 1 0 0 0 1e+00 Zfand2b
Reaction time premature initiations 41.6 1 1 100 0 1e+00 Zfand2b
Std. dev. reaction times 72.92 1 1 100 0 1e+00 Zfand2b
Reaction time trials completed 106.69 1 1 100 0 1e+00 Zfand2b
Reaction time trials AUC 108.76 1 1 100 0 1e+00 Zfand2b
Social response proportion 6.01 1 0 0 0 1e+00 Zfand2b
Cocaine response after cond. corrected 12.71 1 0 0 0 1e+00 Zfand2b
Cocaine response after cond. not corrected 10.73 1 0 0 0 1e+00 Zfand2b
Saline control response 8.43 1 0 0 0 1e+00 Zfand2b
Condit. Reinf. active minus inactive responses 3.61 1 0 0 0 1e+00 Zfand2b
Condit. Reinf. active-inactive response ratio 4.76 1 0 0 0 1e+00 Zfand2b
Condit. Reinf. active responses 2.9 1 0 0 0 1e+00 Zfand2b
Condit. Reinf. lever presses 5.55 1 0 0 0 1e+00 Zfand2b
Condit. Reinf. lever reinforcers received 2.89 1 0 0 0 1e+00 Zfand2b
Pavlov. Cond. intertrial magazine entries 3.16 1 0 0 0 1e+00 Zfand2b
Conditioned reinforcement - actives 152.54 1 1 100 0 1e+00 Zfand2b
Conditioned reinforcement - inactives 135.63 1 1 100 0 1e+00 Zfand2b
Conditioned locomotion 13.93 1 0 0 0 1e+00 Zfand2b
Intermittent access intake day 1-15 change 156.77 1 1 100 0 1e+00 Zfand2b
Intermittent access intake escalation 117.41 1 1 100 0 1e+00 Zfand2b
Intermitt. access day 1 inactive lever presses 169.63 1 1 100 0 1e+00 Zfand2b
Intermitt. access day 15 inactive lever presses 294.26 1 1 100 0 1e+00 Zfand2b
Intermitt. access escalation Index 5.01 1 0 0 0 1e+00 Zfand2b
Intermittent access day 1 total infusions 71.42 1 1 100 0 1e+00 Zfand2b
Intermittent access day 15 total infusions 35.39 1 1 100 0 1e+00 Zfand2b
Intermittent access terminal intake (last 3 days) 25.82 1 1 100 0 1e+00 Zfand2b
Intermittent access day 1 locomotion 26.47 1 1 100 0 1e+00 Zfand2b
Intermittent access day 15 total locomotion 93.08 1 1 100 0 1e+00 Zfand2b
Intermittent access total locomotion 12.43 1 0 0 0 1e+00 Zfand2b
Intermittent access standard deviation 442.51 1 1 100 0 1e+00 Zfand2b
Cocaine induced anxiety 125.35 1 1 100 0 1e+00 Zfand2b
Baseline Anxiety 393.92 1 1 100 0 1e+00 Zfand2b
Incentive Sensitization - Responses 309.83 1 1 100 0 1e+00 Zfand2b
Incentive Sensitization - Breakpoint 300.45 1 1 100 0 1e+00 Zfand2b
Progressive ratio test 1 active lever presses 26.41 1 1 100 0 1e+00 Zfand2b
Progressive ratio test 1 breakpoint 19.19 1 0 0 0 1e+00 Zfand2b
Progressive ratio test 2 active lever presses 109.22 1 1 100 0 1e+00 Zfand2b
Progressive ratio test 2 breakpoint 106.65 1 1 100 0 1e+00 Zfand2b
Progressive ratio test 2 inactive lever presses 63.47 1 1 100 0 1e+00 Zfand2b
Short access day 1 total inactive lever presses 21.93 1 0 0 0 1e+00 Zfand2b
Short access day 10 total inactive lever presses 43.04 1 1 100 0 1e+00 Zfand2b
Short access day 1 total infusions 3.85 1 0 0 0 1e+00 Zfand2b
Short access day 10 total infusions 4.07 1 0 0 0 1e+00 Zfand2b
Short access day 1 locomotion 129.19 1 1 100 0 1e+00 Zfand2b
Short access day 10 total locomotion 432.47 1 1 100 0 1e+00 Zfand2b
Short access total locomotion 209.96 1 1 100 0 1e+00 Zfand2b
Compulsive drug intake 68.39 1 1 100 0 1e+00 Zfand2b
One hour access (0.3 mA shock) 22.58 1 0 0 0 1e+00 Zfand2b
Number of responses in last shaping day 67.75 1 1 100 0 1e+00 Zfand2b
Locomotion distance, session 2 4.45 1 0 0 0 1e+00 Zfand2b
Time in familiar zone, hab. session 1 4.15 1 0 0 0 1e+00 Zfand2b
Bone: elastic displacement 5.56 1 0 0 0 1e+00 Zfand2b
Bone: maximum moment 2.64 1 0 0 0 1e+00 Zfand2b
Breakpoint value in progressive ratio session 4.44 1 0 0 0 1e+00 Zfand2b
Distance traveled before self-admin 5.58 1 0 0 0 1e+00 Zfand2b
Distance traveled after self-admin 8.9 1 0 0 0 1e+00 Zfand2b
Delta time in open arm before/after self-admin 26.67 1 0 0 0 1e+00 Zfand2b
Active lever presses in extinction session 6 26.41 1 0 0 0 1e+00 Zfand2b
Delta ambulatory time before/after self-admin 6.19 1 0 0 0 1e+00 Zfand2b
Time in closed arm before self-admin 44.32 1 1 100 0 1e+00 Zfand2b
Time in open arm before self-admin 24.67 1 0 0 0 1e+00 Zfand2b
Sum of active levers in priming session hrs 5-6 6.97 1 0 0 0 1e+00 Zfand2b
Time to tail flick, vehicle, after self-admin 75.62 1 1 100 0 1e+00 Zfand2b
Time to tail flick, test, before self-admin 10.68 1 0 0 0 1e+00 Zfand2b
Time to tail flick, test, after self-admin 5.63 1 0 0 0 1e+00 Zfand2b
Delta time to tail flick, vehicle, before/after SA 74.6 1 1 100 0 1e+00 Zfand2b
Ambulatory time before self-admin 25.36 1 0 0 0 1e+00 Zfand2b
Ambulatory time after self-admin 4.73 1 0 0 0 1e+00 Zfand2b
Area under the delay curve 31.15 1 1 100 0 1e+00 Zfand2b
Delay disc. indifference point, 0s delay 5.71 1 0 0 0 1e+00 Zfand2b
Delay disc. indifference point, 16s delay 69.03 1 1 100 0 1e+00 Zfand2b
Delay disc. indifference point, 24s delay 27.43 1 0 0 0 1e+00 Zfand2b
Delay disc. indifference point, 8s delay 74.24 1 1 100 0 1e+00 Zfand2b
Delay discount exponential model param 16.14 1 0 0 0 1e+00 Zfand2b
Delay discount hyperbolic model param 15.89 1 0 0 0 1e+00 Zfand2b
Fecal boli incidents, locomotor time 1 176.47 1 1 100 0 1e+00 Zfand2b
Time >=10cm from walls, locomotor time 1 79.04 1 1 100 0 1e+00 Zfand2b
Bouts of movement, locomotor time 1 6.19 1 0 0 0 1e+00 Zfand2b
Rest time, locomotor task time 1 11.47 1 0 0 0 1e+00 Zfand2b
Vertical activity count, locomotor time 1 97.7 1 1 100 0 1e+00 Zfand2b
Bouts of movement, locomotor time 2 23.9 1 0 0 0 1e+00 Zfand2b
Total resting periods, locomotor time 2 36.28 1 1 100 0 1e+00 Zfand2b
Rest time, locomotor task time 2 44.91 1 1 100 0 1e+00 Zfand2b
Distance moved, locomotor task time 2 83.87 1 1 100 0 1e+00 Zfand2b
Vertical activity count, locomotor time 2 13.16 1 0 0 0 1e+00 Zfand2b
Weight adjusted by age 9.91 1 0 0 0 1e+00 Zfand2b
Seeking ratio, delayed vs. immediate footshock 8.74 1 0 0 0 1e+00 Zfand2b
Locomotion in novel chamber post-restriction 14.04 1 0 0 0 1e+00 Zfand2b
Food seeking constrained by brief footshock 14.98 1 0 0 0 1e+00 Zfand2b
Seeking ratio, punishment vs. effort 4.29 1 0 0 0 1e+00 Zfand2b
Run reversals in cocaine runway, females 36.45 1 1 100 0 1e+00 Zfand2b
Latency to leave start box in cocaine runway 34.23 1 1 100 0 1e+00 Zfand2b
Latency to leave start box in cocaine runway, F 31.9 1 1 100 0 1e+00 Zfand2b

Associations by panel

Tissue RNA modality # hits % hits/tests Avg chisq
Adipose alternative polyA 0 0 1.54
Adipose alternative TSS 0 0 1.5
Adipose gene expression 0 0 1.49
Adipose isoform ratio 0 0 1.5
Adipose intron excision ratio 0 0 1.59
Adipose mRNA stability 0 0 1.53
BLA alternative polyA 0 0 1.53
BLA alternative TSS 0 0 1.44
BLA gene expression 0 0 1.49
BLA isoform ratio 0 0 1.47
BLA intron excision ratio 0 0 1.48
BLA mRNA stability 0 0 1.52
Brain alternative polyA 0 0 1.46
Brain alternative TSS 0 0 1.47
Brain gene expression 0 0 1.48
Brain isoform ratio 0 0 1.46
Brain intron excision ratio 0 0 1.51
Brain mRNA stability 0 0 1.45
Eye alternative polyA 0 0 1.47
Eye alternative TSS 0 0 1.33
Eye gene expression 0 0 1.47
Eye isoform ratio 0 0 1.44
Eye intron excision ratio 0 0 1.57
Eye mRNA stability 0 0 1.5
IL alternative polyA 0 0 1.52
IL alternative TSS 0 0 1.31
IL gene expression 0 0 1.48
IL isoform ratio 0 0 1.52
IL intron excision ratio 0 0 1.54
IL mRNA stability 0 0 1.56
LHb alternative polyA 0 0 1.46
LHb alternative TSS 0 0 1.42
LHb gene expression 0 0 1.51
LHb isoform ratio 0 0 1.45
LHb intron excision ratio 0 0 1.52
LHb mRNA stability 0 0 1.48
Liver alternative polyA 0 0 1.47
Liver alternative TSS 0 0 1.48
Liver gene expression 0 0 1.46
Liver isoform ratio 0 0 1.5
Liver intron excision ratio 0 0 1.44
Liver mRNA stability 0 0 1.48
NAcc alternative polyA 0 0 1.47
NAcc alternative TSS 0 0 1.47
NAcc gene expression 0 0 1.49
NAcc isoform ratio 0 0 1.48
NAcc intron excision ratio 0 0 1.49
NAcc mRNA stability 0 0 1.49
OFC alternative polyA 0 0 1.46
OFC alternative TSS 0 0 1.36
OFC gene expression 0 0 1.47
OFC isoform ratio 0 0 1.45
OFC intron excision ratio 0 0 1.58
OFC mRNA stability 0 0 1.49
PL alternative polyA 0 0 1.55
PL alternative TSS 0 0 1.46
PL gene expression 0 0 1.48
PL isoform ratio 0 0 1.47
PL intron excision ratio 1 0 1.49
PL mRNA stability 0 0 1.48
pVTA alternative polyA 0 0 1.58
pVTA alternative TSS 0 0 1.5
pVTA gene expression 0 0 1.45
pVTA isoform ratio 0 0 1.52
pVTA intron excision ratio 0 0 1.53
pVTA mRNA stability 0 0 1.51
RMTg alternative polyA 0 0 1.38
RMTg alternative TSS 0 0 1.37
RMTg gene expression 0 0 1.48
RMTg isoform ratio 0 0 1.33
RMTg intron excision ratio 0 0 1.47
RMTg mRNA stability 0 0 1.38