Hub : Traits

Run reversals in cocaine runway, males

Number of run direction reversals in cocaine runway task, male

Tags: Behavior · Cocaine

Project: u01_tom_jhou

1 locus · 1 gene with independent associations · 1 total associated gene

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr1	168098450	169497201	1	1	2e-07	3.57e-03	3.01e-01	Cyp2r1

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
Tibia length	1.65	1	0	0	0	1e+00	Cyp2r1
Number of licking bursts	8.83	1	0	0	0	1e+00	Cyp2r1
Mean num. licks in bursts	6.4	1	0	0	0	1e+00	Cyp2r1
Patch foraging indifference point 0 sec	3.02	1	0	0	0	1e+00	Cyp2r1
Patch foraging total patch changes 0 sec	3.99	1	0	0	0	1e+00	Cyp2r1
Patch foraging water rate 6 sec	3.31	1	0	0	0	1e+00	Cyp2r1
Reaction time number correct	3.33	1	0	0	0	1e+00	Cyp2r1
Reaction time mean minus median	3.05	1	0	0	0	1e+00	Cyp2r1
Reaction time trials correct on left	3.33	1	0	0	0	1e+00	Cyp2r1
Reaction time trials on left	3.17	1	0	0	0	1e+00	Cyp2r1
Reaction time mean	4.62	1	0	0	0	1e+00	Cyp2r1
Reaction time mean AUC	3.58	1	0	0	0	1e+00	Cyp2r1
Median of all reaction times	3.76	1	0	0	0	1e+00	Cyp2r1
Reaction time premature initiation rate	12.7	1	0	0	0	1e+00	Cyp2r1
Reaction time premature initiations	4.4	1	0	0	0	1e+00	Cyp2r1
Std. dev. reaction times	7.1	1	0	0	0	1e+00	Cyp2r1
Reaction time trials completed	3.17	1	0	0	0	1e+00	Cyp2r1
Social response proportion	6.71	1	0	0	0	1e+00	Cyp2r1
Cocaine response after cond. not corrected	5.17	1	0	0	0	1e+00	Cyp2r1
Intermitt. access day 15 inactive lever presses	5.9	1	0	0	0	1e+00	Cyp2r1
Intermittent access standard deviation	4.12	1	0	0	0	1e+00	Cyp2r1
Short access day 10 total inactive lever presses	12.77	1	0	0	0	1e+00	Cyp2r1
Condit. Reinf. active minus inactive responses	4.39	1	0	0	0	1e+00	Cyp2r1
Condit. Reinf. active-inactive response ratio	8.63	1	0	0	0	1e+00	Cyp2r1
Incentive salience index mean	4.28	1	0	0	0	1e+00	Cyp2r1
Distance traveled before self-admin	7.63	1	0	0	0	1e+00	Cyp2r1
Distance traveled after self-admin	3.54	1	0	0	0	1e+00	Cyp2r1
Diff in mean of infusions in LGA sessions	7.21	1	0	0	0	1e+00	Cyp2r1
Time to tail flick, vehicle, after self-admin	13.61	1	0	0	0	1e+00	Cyp2r1
Ambulatory time before self-admin	9.94	1	0	0	0	1e+00	Cyp2r1
Ambulatory time after self-admin	5.66	1	0	0	0	1e+00	Cyp2r1
Fecal boli incidents, locomotor time 1	5.11	1	0	0	0	1e+00	Cyp2r1
Bouts of movement, locomotor time 2	4.12	1	0	0	0	1e+00	Cyp2r1
Locomotion in novel chamber post-restriction	13.5	1	0	0	0	1e+00	Cyp2r1
Run reversals in cocaine runway, females	4.3	1	0	0	0	1e+00	Cyp2r1
Latency to leave start box in cocaine runway	9.58	1	0	0	0	1e+00	Cyp2r1
Latency to leave start box in cocaine runway, F	7.46	1	0	0	0	1e+00	Cyp2r1
K content in liver	13.95	1	0	0	0	1e+00	Cyp2r1
Mg content in liver	7.61	1	0	0	0	1e+00	Cyp2r1
Zn content in liver	6.28	1	0	0	0	1e+00	Cyp2r1

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.05
Adipose	alternative TSS	0	0	0.95
Adipose	gene expression	0	0	0.98
Adipose	isoform ratio	0	0	0.95
Adipose	intron excision ratio	0	0	0.97
Adipose	mRNA stability	0	0	0.94
BLA	alternative polyA	0	0	1.05
BLA	alternative TSS	0	0	1.04
BLA	gene expression	0	0	0.96
BLA	isoform ratio	0	0	1
BLA	intron excision ratio	0	0	0.94
BLA	mRNA stability	0	0	0.93
Brain	alternative polyA	0	0	0.99
Brain	alternative TSS	0	0	0.99
Brain	gene expression	0	0	0.95
Brain	isoform ratio	0	0	0.99
Brain	intron excision ratio	0	0	0.97
Brain	mRNA stability	0	0	0.96
Eye	alternative polyA	0	0	1.18
Eye	alternative TSS	0	0	0.89
Eye	gene expression	0	0	0.98
Eye	isoform ratio	0	0	1.09
Eye	intron excision ratio	0	0	0.85
Eye	mRNA stability	0	0	0.92
IL	alternative polyA	0	0	0.97
IL	alternative TSS	0	0	0.89
IL	gene expression	0	0	0.93
IL	isoform ratio	0	0	0.91
IL	intron excision ratio	0	0	0.92
IL	mRNA stability	0	0	0.98
LHb	alternative polyA	0	0	1.01
LHb	alternative TSS	0	0	1.01
LHb	gene expression	0	0	0.94
LHb	isoform ratio	0	0	1.02
LHb	intron excision ratio	0	0	0.98
LHb	mRNA stability	0	0	0.92
Liver	alternative polyA	0	0	1.07
Liver	alternative TSS	0	0	1
Liver	gene expression	0	0	0.95
Liver	isoform ratio	0	0	0.99
Liver	intron excision ratio	0	0	0.96
Liver	mRNA stability	1	0	0.97
NAcc	alternative polyA	0	0	1.03
NAcc	alternative TSS	0	0	1.06
NAcc	gene expression	0	0	0.96
NAcc	isoform ratio	0	0	0.97
NAcc	intron excision ratio	0	0	0.98
NAcc	mRNA stability	0	0	0.94
OFC	alternative polyA	0	0	1.04
OFC	alternative TSS	0	0	0.9
OFC	gene expression	0	0	0.94
OFC	isoform ratio	0	0	1
OFC	intron excision ratio	0	0	0.93
OFC	mRNA stability	0	0	0.94
PL	alternative polyA	0	0	1
PL	alternative TSS	0	0	0.99
PL	gene expression	0	0	0.96
PL	isoform ratio	0	0	0.96
PL	intron excision ratio	0	0	0.96
PL	mRNA stability	0	0	0.95
pVTA	alternative polyA	0	0	1.03
pVTA	alternative TSS	0	0	0.98
pVTA	gene expression	0	0	0.95
pVTA	isoform ratio	0	0	1
pVTA	intron excision ratio	0	0	0.97
pVTA	mRNA stability	0	0	0.98
RMTg	alternative polyA	0	0	0.94
RMTg	alternative TSS	0	0	0.91
RMTg	gene expression	0	0	0.96
RMTg	isoform ratio	0	0	0.92
RMTg	intron excision ratio	0	0	0.92
RMTg	mRNA stability	0	0	0.95