B3gnt6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative polyA XM_006229745.5 0.03 0.02 1.5e-03 0.02 0.03 0.03 0.03 4.5e-03 2.1e-04 3.8e-04 3.4e-04
2 PL alternative polyA NM_001106211.1 0.04 0.03 5.3e-04 0.02 0.04 0.03 0.03 2.3e-03 6.5e-05 1.5e-04 2.0e-04
3 LHb gene expression B3gnt6 0.24 0.14 2.5e-03 0.06 0.07 0.04 0.08 2.0e-02 1.2e-02 5.1e-02 5.9e-03
4 pVTA gene expression B3gnt6 0.13 0.07 2.0e-10 0.14 0.12 0.11 0.13 5.0e-11 1.0e-09 4.2e-09 2.3e-10
5 OFC alternative polyA NM_001106211.1 0.14 0.1 8.7e-03 0.06 0.05 0.06 0.06 1.3e-02 2.5e-02 1.7e-02 1.3e-02
6 PL isoform ratio XM_006229745.5 0.14 0.07 7.6e-15 0.14 0.14 0.15 0.15 1.3e-15 2.2e-15 8.4e-16 2.4e-16
7 PL gene expression B3gnt6 0.4 0.12 0.0e+00 0.43 0.45 0.45 0.45 5.9e-51 6.1e-54 6.5e-54 1.6e-54
8 BLA alternative polyA NM_001106211.1 0.06 0.04 5.7e-03 0 0 -0 -0 2.4e-01 2.9e-01 4.2e-01 8.4e-01
9 BLA alternative polyA XM_006229745.5 0.05 0.04 8.1e-03 0 -0 -0 -0 3.0e-01 3.6e-01 4.7e-01 9.5e-01
10 BLA isoform ratio XM_006229745.5 0.11 0.07 3.6e-05 0.09 0.07 0.09 0.09 1.1e-05 2.2e-04 1.8e-05 2.1e-05
11 NAcc alternative polyA NM_001106211.1 0.01 0.01 9.3e-03 0.01 0.01 0.01 0.01 1.7e-03 3.3e-03 1.8e-03 4.0e-03
12 OFC alternative polyA XM_006229745.5 0.14 0.1 8.6e-03 0.07 0.06 0.06 0.07 8.2e-03 1.6e-02 1.2e-02 9.2e-03
13 IC gene expression B3gnt6 0.38 0.14 2.1e-13 0.22 0.26 0.25 0.27 1.3e-09 1.9e-11 6.3e-11 1.3e-11
14 OFC gene expression B3gnt6 0.31 0.15 1.8e-05 0.19 0.2 0.18 0.2 3.3e-05 1.8e-05 3.6e-05 1.9e-05
15 BLA gene expression B3gnt6 0.45 0.13 0.0e+00 0.33 0.34 0.33 0.33 6.9e-18 1.9e-18 2.4e-18 2.8e-18
16 NAcc gene expression B3gnt6 0.11 0.06 0.0e+00 0.09 0.12 0.11 0.11 1.4e-13 6.4e-18 6.4e-17 1.4e-16
17 IC isoform ratio XM_006229745.5 0.27 0.16 1.4e-04 0.06 0.07 0.08 0.07 2.3e-03 4.9e-04 3.8e-04 6.2e-04
18 Adipose gene expression B3gnt6 0.79 0.07 0.0e+00 0.14 0.3 0.32 0.28 3.3e-15 3.2e-33 7.3e-36 7.5e-32
19 Brain gene expression B3gnt6 0.13 0.07 4.4e-11 0.12 0.11 0.1 0.11 6.3e-11 2.2e-10 6.4e-10 2.8e-10
20 IC alternative TSS XM_006229745.5 0.39 0.17 8.1e-06 0.09 0.1 0.07 0.08 1.9e-04 3.9e-05 4.9e-04 3.5e-04
21 IL gene expression B3gnt6 0.4 0.14 1.3e-06 0.03 0.12 0.14 0.09 5.5e-02 9.1e-04 2.8e-04 4.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.10.10.80.3-0.30.70.80.00.2-0.3-0.30.30.3-0.30.1-0.2-0.1-0.1-0.20.20.9-0.20.3-0.2
Area under the delay curve0.40.53.0-0.60.5-0.3-0.21.3-0.60.70.5-0.5-0.50.3-1.70.20.80.40.70.2-0.90.8-0.00.3
BMI with tail2.06.813.21.7-1.70.5-0.4-3.52.2-2.9-3.13.13.1-2.63.6-3.1-3.2-2.8-3.22.30.7-2.62.1-2.7
BMI without tail2.57.814.91.5-1.50.0-1.2-3.92.4-2.9-3.03.03.0-2.53.7-3.2-3.6-2.8-3.62.3-0.7-3.82.2-3.4
Body weight2.19.120.61.7-1.60.2-1.1-4.52.3-3.2-3.53.53.5-2.84.2-3.4-4.0-3.1-3.92.00.5-3.72.1-3.4
Weight adjusted by age0.40.61.50.2-0.3-0.7-0.7-0.50.6-0.5-0.60.60.6-0.60.4-0.9-0.9-0.9-1.01.0-1.1-1.20.9-1.0
Bone surface0.40.71.9-1.41.3-1.2-1.21.0-0.90.80.8-0.8-0.80.7-1.00.40.70.60.30.0-0.7-1.1-0.1-0.0
Bone volume0.10.31.9-0.60.5-0.6-0.80.4-0.00.10.1-0.1-0.1-0.1-0.4-0.20.0-0.1-0.30.6-0.7-1.40.6-0.5
Breakpoint value in progressive ratio session0.30.42.90.6-0.61.11.10.10.2-0.2-0.20.20.20.40.10.30.3-0.10.4-0.21.71.20.1-0.2
Number of licking bursts2.64.26.02.4-2.42.42.2-2.02.0-2.1-2.32.32.3-2.42.2-2.3-1.9-2.0-1.71.72.3-0.11.7-1.0
Context. condit. distance diff. score1.51.83.6-1.71.6-1.2-1.11.9-1.61.51.4-1.4-1.41.5-1.91.41.71.21.3-0.8-0.70.0-0.50.6
Locomotion velocity, session 10.80.82.1-0.30.20.10.41.5-0.40.91.1-1.1-1.10.7-1.40.91.20.71.3-0.4-0.61.3-0.41.1
Locomotion distance, session 10.81.11.6-1.01.0-0.8-0.80.7-1.11.11.1-1.1-1.11.0-0.91.21.11.01.2-1.3-0.40.9-1.11.2
Locomotion velocity, session 20.40.42.1-0.50.4-0.7-0.81.1-0.20.50.8-0.8-0.80.6-0.90.50.50.20.50.1-1.50.00.10.0
Locomotion distance, session 20.20.30.8-0.50.6-0.8-0.80.1-0.40.50.6-0.6-0.60.6-0.30.70.30.50.4-0.7-0.90.1-0.70.4
Locomotion velocity, session 30.20.30.6-0.50.5-0.4-0.30.7-0.40.60.6-0.6-0.60.6-0.80.50.60.40.5-0.2-0.70.2-0.20.3
Locomotion distance, session 31.21.32.6-1.11.1-0.7-0.61.5-1.01.21.3-1.3-1.31.0-1.51.11.61.01.4-0.6-0.60.9-0.61.3
Stereotopy head waving bouts, day 30.70.82.51.1-0.90.70.4-1.60.8-1.1-1.01.01.0-0.61.5-0.7-1.4-0.6-1.00.00.4-0.3-0.1-0.8
Stereotopy head waving duration, day 30.30.31.1-0.50.6-0.4-0.6-0.0-0.70.40.5-0.5-0.50.80.00.80.20.80.4-1.0-0.1-0.2-1.00.1
Locomotion velocity, session 70.30.31.40.5-0.60.60.90.80.6-0.1-0.20.20.2-0.6-0.7-0.60.1-0.5-0.01.2-0.20.20.90.1
Locomotion distance, session 70.30.41.80.3-0.40.20.10.50.6-0.4-0.40.40.4-0.9-0.4-0.9-0.1-0.8-0.41.4-0.4-0.51.2-0.0
Stereotopy head waving bouts, day 72.22.54.4-1.61.6-1.2-0.91.2-1.81.71.7-1.7-1.72.0-1.32.11.51.81.6-2.0-0.70.7-1.91.0
Stereotopy head waving duration, day 71.92.34.1-1.81.8-1.6-1.40.9-1.81.61.6-1.6-1.62.0-1.02.01.21.71.2-1.9-0.8-0.0-1.70.5
Locomotion velocity, session 82.63.19.8-1.91.8-1.2-1.03.1-1.61.91.9-1.9-1.91.7-3.01.62.31.31.7-0.4-1.70.2-0.20.9
Locomotion distance, session 81.42.12.9-1.71.7-1.5-1.51.4-1.61.61.6-1.6-1.61.7-1.61.71.51.31.3-1.3-1.20.2-0.90.7
Degree of sensitization distance1.61.63.00.9-0.90.2-0.0-1.21.1-1.3-1.41.41.4-1.31.3-1.6-1.7-1.5-1.71.4-0.1-1.71.3-1.4
Degree of sensitization stereotypy4.65.07.5-2.42.5-2.0-1.52.0-2.62.52.5-2.5-2.52.7-2.12.72.32.42.3-2.5-0.91.0-2.31.5
Conditioned locomotion0.10.20.5-0.10.10.10.30.6-0.20.40.4-0.4-0.40.3-0.60.30.50.40.5-0.2-0.20.7-0.30.6
Cocaine response after cond. corrected0.81.02.61.0-1.11.01.00.10.9-1.0-1.11.11.1-1.30.3-1.2-0.5-1.3-0.71.51.0-0.11.6-0.6
Cocaine response after cond. not corrected0.20.21.30.3-0.30.50.50.40.0-0.2-0.30.30.3-0.4-0.2-0.40.2-0.40.10.51.10.50.50.2
Cocaine response before conditioning1.72.15.4-1.31.5-0.7-0.70.3-1.71.41.5-1.5-1.51.6-0.71.61.22.01.5-2.20.01.2-2.31.5
Saline control response0.71.03.0-1.41.5-1.7-1.7-0.3-1.20.80.8-0.8-0.81.00.20.80.30.90.4-1.2-0.2-0.9-1.20.3
Bone: connectivity density0.30.41.3-0.60.50.20.41.2-0.60.60.6-0.6-0.60.6-1.10.70.90.80.8-0.40.50.4-0.30.4
Bone: cortical apparent density0.60.91.51.2-1.21.21.0-0.81.1-1.0-1.01.01.0-1.00.8-1.0-0.7-1.0-0.71.00.70.21.0-0.5
Bone: cortical area0.50.82.8-0.10.0-0.4-0.4-0.70.4-0.8-0.90.90.9-0.80.9-1.2-0.8-0.8-1.11.10.6-1.70.9-1.0
Bone: cortical porosity1.21.33.0-1.01.0-0.7-0.70.6-1.31.21.1-1.1-1.11.3-0.81.50.91.31.1-1.7-0.31.1-1.61.1
Bone: cortical porosity1.21.32.8-0.91.0-0.7-0.70.6-1.31.31.2-1.2-1.21.4-0.81.50.91.41.2-1.7-0.51.0-1.71.0
Bone: cortical thickness0.71.22.41.0-1.01.11.0-0.90.8-1.3-1.41.41.4-1.21.0-1.4-0.9-1.0-1.01.11.5-0.41.0-0.7
Bone: cortical thickness0.00.00.2-0.20.1-0.2-0.20.1-0.1-0.0-0.20.20.2-0.30.0-0.40.1-0.3-0.10.40.3-0.10.40.1
Bone: cortical tissue density0.50.71.51.2-1.21.21.0-0.71.0-0.9-0.80.80.8-0.90.7-0.9-0.6-0.8-0.50.90.60.40.9-0.4
Condit. Reinf. active minus inactive responses1.01.22.30.5-0.50.1-0.2-1.30.9-1.2-1.31.31.3-1.11.3-1.1-1.3-1.1-1.40.80.3-1.51.0-1.3
Condit. Reinf. active-inactive response ratio0.60.72.10.1-0.1-0.3-0.5-1.10.5-0.9-0.90.90.9-0.61.1-0.7-1.0-0.7-1.10.30.2-1.50.5-1.2
Condit. Reinf. active responses0.81.01.60.8-0.80.30.2-1.21.0-1.2-1.21.21.2-1.11.3-1.0-1.2-1.1-1.20.70.3-1.10.9-1.1
Condit. Reinf. inactive responses0.10.10.30.5-0.50.30.4-0.20.5-0.3-0.30.30.3-0.40.2-0.3-0.3-0.4-0.20.4-0.1-0.00.4-0.1
Incentive salience index mean0.60.81.50.5-0.60.0-0.2-0.70.9-0.9-1.01.01.0-0.90.7-1.0-0.9-1.1-1.11.0-0.3-1.21.2-1.2
Condit. Reinf. lever presses0.10.11.00.0-0.1-0.2-0.10.70.30.10.1-0.1-0.1-0.1-0.6-0.10.1-0.4-0.10.6-1.0-0.20.7-0.3
Condit. Reinf. active minus inactive responses2.22.810.3-2.62.6-3.2-3.20.4-1.91.51.3-1.3-1.31.6-0.61.00.81.00.4-1.1-1.7-2.0-1.0-0.1
Condit. Reinf. active-inactive response ratio0.30.31.2-0.80.7-1.1-1.10.4-0.50.50.3-0.3-0.30.4-0.40.00.3-0.10.00.3-0.5-0.80.3-0.2
Condit. Reinf. active responses3.24.416.8-3.23.2-4.1-4.10.3-2.21.81.6-1.6-1.61.8-0.61.20.81.30.4-1.3-2.4-2.8-1.3-0.0
Condit. Reinf. inactive responses2.22.911.0-2.32.4-3.1-3.3-0.2-1.61.21.2-1.2-1.21.4-0.21.10.31.20.2-1.5-2.5-2.2-1.60.1
Condit. Reinf. lever presses10.915.032.5-5.55.5-5.7-5.52.4-4.64.13.9-3.9-3.94.2-2.73.63.13.62.6-3.3-2.8-1.8-3.21.5
Condit. Reinf. lever reinforcers received3.65.018.2-3.43.4-4.3-4.30.4-2.42.01.8-1.8-1.81.9-0.81.31.01.50.6-1.5-2.4-2.7-1.50.1
Conditioned reinforcement - actives0.81.42.9-1.51.4-1.1-1.01.5-1.31.41.1-1.1-1.11.7-1.31.41.31.21.2-1.0-0.50.3-0.90.3
Conditioned reinforcement - inactives0.40.61.7-0.10.10.40.70.9-0.50.60.7-0.7-0.71.3-0.61.10.70.70.9-0.91.01.3-0.6-0.0
Conditioned locomotion3.03.95.5-2.12.1-1.4-1.12.3-2.32.32.2-2.2-2.22.3-2.32.22.32.12.2-1.7-0.81.2-1.81.6
Patch foraging indifference point 0 sec2.34.28.8-2.93.0-2.8-2.91.0-2.52.22.1-2.1-2.12.3-1.02.11.42.11.3-2.2-0.7-0.9-2.20.8
Patch foraging indifference point AUC0.10.20.8-0.10.0-0.3-0.4-0.20.3-0.3-0.30.30.3-0.40.5-0.5-0.3-0.4-0.50.6-0.2-0.90.6-0.4
Delay disc. indifference point, 0s delay0.50.51.9-1.01.0-1.4-1.40.4-0.80.70.6-0.6-0.60.6-0.40.40.40.40.3-0.3-1.1-0.5-0.40.1
Delay disc. indifference point, 16s delay0.50.64.5-0.20.20.30.41.5-0.20.50.4-0.4-0.40.3-2.10.20.90.40.80.3-1.21.00.00.6
Delay disc. indifference point, 2s delay1.11.22.6-1.41.4-1.4-1.30.8-1.61.41.1-1.1-1.11.2-1.11.11.01.01.0-1.0-0.60.3-1.00.5
Delay disc. indifference point, 24s delay0.60.72.00.9-1.01.31.10.21.0-0.8-0.70.70.7-1.2-0.5-1.2-0.2-0.8-0.31.4-0.20.51.0-0.0
Delay disc. indifference point, 4s delay0.50.62.5-0.90.8-1.4-1.51.0-0.50.60.4-0.4-0.40.3-1.00.00.4-0.10.20.5-1.6-0.30.3-0.3
Delay disc. indifference point, 8s delay0.40.52.7-0.70.7-0.3-0.21.5-0.70.80.6-0.6-0.60.5-1.60.40.90.60.70.1-0.50.6-0.10.3
Indifference point function ln k1.52.63.8-1.61.7-0.8-0.91.3-1.91.81.7-1.7-1.71.9-1.81.91.61.91.7-1.9-0.50.9-1.91.2
Indifference point function log k1.52.63.8-1.61.7-0.8-0.91.3-1.91.81.7-1.7-1.71.9-1.81.91.61.91.7-1.9-0.50.9-1.91.2
Patch foraging total patch changes 0 sec1.93.67.8-2.82.8-2.4-2.71.0-2.32.01.9-1.9-1.92.2-0.91.91.41.91.2-2.1-0.4-0.8-2.00.7
Patch foraging total patch changes 12 sec0.30.42.2-0.90.9-1.2-1.5-0.1-0.40.0-0.10.10.10.20.70.0-0.30.0-0.5-0.1-0.3-1.5-0.0-0.7
Patch foraging total patch changes 18 sec0.60.94.8-1.51.4-1.6-2.20.3-0.70.60.5-0.5-0.50.70.30.30.10.4-0.2-0.2-1.0-2.0-0.2-0.7
Patch foraging total patch changes 24 sec0.20.31.8-0.60.6-0.7-1.3-0.3-0.20.10.0-0.0-0.00.20.80.0-0.2-0.1-0.3-0.00.1-1.20.1-0.5
Patch foraging total patch changes 6 sec0.71.12.5-1.51.6-1.0-1.10.2-1.41.00.9-0.9-0.91.0-0.31.00.81.30.7-1.40.6-0.4-1.40.7
Patch foraging time to switch 0 sec1.42.87.42.6-2.52.22.7-1.01.9-1.7-1.71.71.7-1.71.1-1.5-1.3-1.4-0.91.21.41.31.1-0.4
Patch foraging water rate 0 sec1.42.96.9-2.62.5-2.1-2.61.4-2.11.81.7-1.7-1.71.9-1.01.71.51.61.2-1.5-0.8-1.1-1.30.6
Patch foraging water rate 12 sec1.22.54.0-2.02.0-1.6-1.91.2-1.81.81.8-1.8-1.81.9-1.31.81.51.61.4-1.5-0.8-0.4-1.40.7
Patch foraging water rate 18 sec0.20.41.3-0.90.9-0.7-1.10.4-0.60.50.6-0.6-0.60.7-0.50.60.50.30.3-0.4-0.7-0.5-0.1-0.1
Patch foraging water rate 24 sec1.31.93.1-1.51.4-0.8-0.81.8-1.51.61.6-1.6-1.61.6-1.41.61.71.41.5-1.2-0.30.5-1.01.0
Patch foraging water rate 6 sec0.91.32.2-1.21.2-0.7-0.71.4-1.41.31.2-1.2-1.21.5-1.11.51.31.21.2-1.2-0.00.2-1.00.6
Seeking ratio, delayed vs. immediate footshock1.21.42.81.6-1.71.71.70.21.5-1.3-1.21.21.2-1.4-0.4-1.2-0.6-1.3-0.71.6-0.00.41.6-0.5
Distance traveled before self-admin0.20.30.70.7-0.70.80.8-0.70.8-0.6-0.30.30.3-0.70.8-0.6-0.4-0.5-0.40.40.50.20.40.2
Distance traveled after self-admin0.50.63.00.8-0.71.21.5-0.50.0-0.00.2-0.2-0.2-0.50.60.00.10.40.5-0.61.11.7-0.81.4
Extensor digitorum longus weight0.62.24.00.9-1.00.3-0.1-1.01.4-1.5-1.61.61.6-1.61.2-1.8-1.6-1.8-1.92.00.0-1.92.0-1.9
Bone: elastic displacement0.50.62.81.0-1.11.51.7-0.10.7-0.5-0.70.70.7-0.80.1-0.4-0.2-0.6-0.20.51.20.50.8-0.1
Bone: elastic work0.60.84.21.0-1.11.82.10.70.6-0.3-0.40.40.4-0.6-0.5-0.30.3-0.20.30.71.51.10.60.4
Bone: endosteal estimation0.40.94.5-0.90.8-1.7-1.9-0.10.2-0.00.0-0.0-0.0-0.20.1-0.6-0.4-0.4-0.80.9-1.8-2.10.6-0.8
Bone: endosteal perimeter0.71.55.8-1.71.6-2.4-2.40.8-0.60.80.8-0.8-0.80.7-0.80.30.40.2-0.10.3-2.3-2.10.2-0.5
Epididymis fat weight1.44.87.82.0-2.01.60.9-2.72.2-2.5-2.72.72.7-2.62.7-2.8-2.4-2.3-2.32.01.2-1.21.8-1.5
Delta time in closed arm before/after self-admin1.31.23.31.0-1.10.70.6-0.31.3-1.1-1.11.11.1-0.80.3-1.1-0.9-1.4-1.11.50.2-0.91.8-1.7
Delta time in open arm before/after self-admin1.11.13.3-1.51.5-1.8-1.80.4-0.91.01.0-1.0-1.01.3-0.21.00.60.70.3-0.9-0.8-1.1-0.5-0.3
Diff in mean of infusions in LGA sessions3.13.78.02.6-2.62.82.7-1.72.2-2.1-2.22.22.2-1.61.4-1.6-1.4-1.6-1.01.12.41.21.3-0.9
Delay discount exponential model param0.40.52.80.6-0.50.30.2-1.20.6-0.7-0.50.50.5-0.41.7-0.2-0.9-0.4-0.7-0.20.8-0.80.1-0.3
Extinction: sum of active levers before priming0.20.21.3-0.10.1-0.5-0.6-0.10.2-0.2-0.10.10.10.70.10.2-0.2-0.4-0.30.10.3-0.80.4-1.2
Active lever presses in extinction session 65.05.09.6-2.02.1-1.1-0.71.3-2.52.42.4-2.4-2.42.8-1.32.82.22.72.5-3.11.21.8-3.02.0
Bone: final force0.10.11.4-0.20.20.30.50.2-0.3-0.0-0.20.20.2-0.3-0.1-0.50.30.10.10.41.2-0.10.10.4
Bone: final moment0.10.11.1-0.30.30.10.20.1-0.30.0-0.20.20.2-0.20.0-0.40.20.10.00.21.0-0.20.00.3
Food consumed during 24 hour testing period3.34.66.7-2.22.3-2.1-1.92.0-2.02.32.6-2.6-2.62.6-2.02.52.02.22.0-1.9-2.10.5-2.11.4
Glucose0.20.31.40.2-0.2-0.3-0.2-0.10.5-0.4-0.40.40.4-0.60.2-0.8-0.3-0.8-0.51.2-0.3-0.41.0-0.4
Heart weight0.20.30.9-0.90.9-0.7-0.80.1-0.80.60.4-0.4-0.40.4-0.40.20.50.60.3-0.4-0.0-0.3-0.60.4
Delay discount hyperbolic model param0.40.42.40.6-0.50.50.5-1.20.6-0.7-0.50.50.5-0.41.6-0.2-0.8-0.3-0.6-0.20.9-0.5-0.0-0.2
Intermittent access intake day 1-15 change1.73.44.8-2.02.0-1.5-1.12.0-2.22.22.1-2.1-2.12.1-2.12.01.92.01.8-1.6-1.20.7-1.81.4
Intermittent access intake escalation1.83.85.4-2.22.2-1.6-1.22.2-2.32.32.2-2.2-2.22.2-2.32.12.12.12.0-1.6-1.10.7-1.81.5
Intermittent access intake escalation 21.51.72.6-1.51.5-1.2-0.91.5-1.61.61.4-1.4-1.41.5-1.51.41.31.41.2-1.1-0.90.4-1.31.0
Intermitt. access day 1 inactive lever presses0.20.83.71.4-1.41.71.9-0.10.7-0.7-0.20.20.2-0.20.3-0.1-0.3-0.5-0.10.21.51.40.5-0.4
Intermitt. access day 15 inactive lever presses0.51.04.21.4-1.41.71.9-0.30.7-0.7-0.40.40.40.20.5-0.0-0.4-0.5-0.2-0.12.01.40.3-0.9
Intermitt. access escalation Index0.10.10.50.1-0.10.40.70.20.00.10.1-0.1-0.1-0.0-0.20.20.40.20.4-0.20.10.5-0.10.5
Intermittent access day 1 total infusions0.40.71.6-1.01.0-0.8-0.71.2-0.81.00.8-0.8-0.81.0-1.20.91.00.70.8-0.5-0.60.0-0.30.2
Intermittent access day 15 total infusions2.84.27.8-2.32.2-1.7-1.32.8-2.32.42.2-2.2-2.22.4-2.72.22.32.02.1-1.4-1.30.6-1.51.2
Intermittent access terminal intake (last 3 days)2.22.94.9-2.02.0-1.7-1.32.2-2.02.01.7-1.7-1.72.1-2.11.91.71.71.5-1.3-1.3-0.0-1.30.6
Intermittent access total infusions1.01.22.8-1.41.3-1.2-1.11.7-1.21.31.0-1.0-1.01.3-1.51.11.10.90.8-0.5-1.1-0.3-0.50.1
Intermittent access day 1 locomotion0.40.51.3-0.60.5-0.20.11.1-0.60.70.7-0.7-0.70.8-1.00.80.90.70.8-0.5-0.20.6-0.40.5
Intermittent access day 15 total locomotion1.62.93.9-1.81.8-1.5-1.01.7-1.92.01.9-1.9-1.91.9-2.01.81.71.91.7-1.6-1.10.7-1.81.3
Intermittent access total locomotion0.70.91.4-1.21.2-1.0-0.81.2-1.11.10.9-0.9-0.91.0-1.10.91.01.00.8-0.6-0.90.1-0.80.6
Intermittent access standard deviation0.10.21.1-0.20.2-0.5-0.9-0.00.2-0.2-0.00.00.00.20.3-0.2-0.5-0.4-0.60.4-0.6-1.00.3-1.0
Left kidney weight0.62.67.10.6-0.6-0.7-1.4-2.31.2-1.5-1.51.51.5-1.21.9-1.6-2.3-1.6-2.21.1-1.6-2.70.9-2.1
Right kidney weight0.62.78.20.5-0.4-1.1-1.5-2.51.1-1.3-1.31.31.3-1.11.9-1.6-2.3-1.6-2.21.1-1.6-2.90.9-2.1
Cocaine induced anxiety1.42.03.11.8-1.71.61.5-1.21.7-1.7-1.61.61.6-1.41.5-1.4-1.5-1.3-1.31.21.30.11.0-1.0
Post-drug Anxiety1.21.32.11.4-1.41.41.4-0.61.4-1.3-1.21.21.2-1.21.0-1.2-0.9-1.1-0.91.31.00.21.1-0.6
Baseline Anxiety0.50.51.3-0.80.7-0.6-0.51.2-0.70.80.9-0.9-0.90.3-1.10.40.80.40.60.0-1.1-0.10.10.7
Tail length1.24.517.10.6-0.5-1.1-2.0-2.91.6-1.8-1.71.71.7-1.62.0-2.0-2.7-2.0-2.81.5-2.5-4.11.7-2.8
Length with tail1.04.212.60.7-0.7-0.6-1.4-3.41.4-1.9-2.12.12.1-1.72.6-2.0-2.8-2.0-2.81.0-0.8-3.61.3-2.5
Length without tail0.31.03.30.8-0.70.80.5-1.80.5-1.0-1.11.11.1-0.71.7-0.7-1.2-0.6-0.8-0.31.7-0.1-0.1-0.4
Times rat made contact with spout0.70.81.40.9-0.80.50.2-1.11.0-1.1-0.90.90.9-0.71.1-0.8-1.2-0.9-1.10.7-0.2-1.00.7-1.2
Lifetime Intake1.51.83.8-1.61.6-1.3-1.22.0-1.51.61.4-1.4-1.41.3-1.71.31.41.21.2-0.7-1.4-0.0-0.70.7
Liver weight, left0.81.32.40.8-0.80.3-0.3-1.51.0-1.3-1.21.21.2-1.11.1-1.3-1.5-1.4-1.41.1-0.0-1.11.1-1.4
Liver weight, right3.46.09.92.2-2.20.90.1-3.02.6-2.7-2.82.82.8-2.62.7-2.9-3.1-2.8-3.02.30.0-2.22.2-2.5
Locomotor activity0.40.72.6-0.80.9-1.2-1.4-0.3-0.40.60.8-0.8-0.80.7-0.00.5-0.10.80.0-0.7-1.6-1.2-1.20.0
Locomotor testing distance0.50.94.6-1.01.0-1.6-2.1-0.6-0.20.10.2-0.2-0.20.30.5-0.1-0.60.1-0.6-0.0-1.5-2.1-0.5-0.9
Locomotor testing rearing0.71.54.90.2-0.1-0.3-1.3-1.70.7-1.2-1.21.21.2-0.62.0-1.0-1.7-0.9-1.60.5-0.0-2.20.4-1.8
Locomotion in novel chamber1.31.72.7-1.41.4-0.9-0.81.6-1.41.51.5-1.5-1.51.3-1.61.21.51.41.4-0.8-0.80.6-1.11.2
Locomotion in novel chamber post-restriction3.04.96.7-2.62.6-1.8-1.72.0-2.42.52.6-2.6-2.62.4-2.32.52.52.42.3-2.0-0.90.5-2.02.0
Fecal boli incidents, locomotor time 11.01.43.6-1.31.2-0.8-0.51.9-1.11.31.4-1.4-1.41.3-1.71.31.61.11.4-0.6-0.30.2-0.60.8
Change in fecal boli incidents, locomotor task0.30.31.20.9-0.81.10.8-0.80.3-0.6-0.40.40.4-0.50.4-0.4-0.6-0.3-0.30.10.10.6-0.10.3
Time >=10cm from walls, locomotor time 12.42.54.5-1.81.8-1.2-1.01.4-1.71.81.8-1.8-1.81.9-1.02.11.81.81.7-1.90.30.6-1.51.1
Bouts of movement, locomotor time 10.10.10.3-0.40.4-0.5-0.50.3-0.10.30.5-0.5-0.50.3-0.20.30.50.10.40.1-0.5-0.10.10.2
Total resting periods, locomotor time 10.20.20.6-0.30.3-0.1-0.10.6-0.30.50.5-0.5-0.50.4-0.40.50.80.30.7-0.0-0.10.5-0.10.5
Rest time, locomotor task time 10.40.42.0-0.10.10.40.31.0-0.30.50.5-0.5-0.50.4-1.10.51.00.41.1-0.0-0.01.4-0.11.0
Distance moved, locomotor task time 10.40.62.50.0-0.1-0.7-0.7-0.60.4-0.6-0.60.60.6-0.60.8-0.8-1.0-0.8-1.20.7-0.6-1.60.8-1.4
Vertical activity count, locomotor time 10.10.31.5-0.40.3-0.9-0.8-0.30.0-0.2-0.10.10.1-0.40.4-0.6-0.6-0.3-0.80.5-0.8-1.20.3-0.7
Time >=10cm from walls, locomotor time 20.30.52.0-1.01.0-1.2-1.40.3-0.70.70.7-0.7-0.70.80.20.90.50.40.4-0.6-0.1-0.3-0.40.1
Bouts of movement, locomotor time 20.50.83.5-0.80.8-1.1-1.30.5-0.50.61.0-1.0-1.01.0-1.10.70.20.40.3-0.5-1.9-0.6-0.6-0.3
Total resting periods, locomotor time 20.30.62.8-0.60.6-0.9-1.00.5-0.40.50.9-0.9-0.90.8-1.10.60.30.40.3-0.4-1.7-0.4-0.5-0.1
Rest time, locomotor task time 20.81.12.91.4-1.31.71.6-0.51.2-1.0-1.21.21.2-1.20.7-1.0-0.5-0.7-0.40.81.20.30.60.0
Distance moved, locomotor task time 20.80.94.2-1.41.3-2.1-2.00.4-0.80.70.9-0.9-0.90.8-0.20.50.20.30.0-0.2-1.5-0.8-0.2-0.3
Vertical activity count, locomotor time 20.30.42.1-0.70.7-1.4-1.4-0.0-0.10.10.4-0.4-0.40.10.1-0.1-0.3-0.2-0.60.3-1.2-1.00.3-0.7
Light reinforcement 10.92.35.31.8-1.71.41.5-2.31.5-1.6-1.71.71.7-1.71.8-1.6-1.6-1.4-1.30.81.3-0.11.0-0.7
Light reinforcement 20.20.20.9-0.10.2-0.00.2-1.0-0.40.30.3-0.3-0.30.20.40.20.10.40.4-0.70.80.7-0.80.7
Bone: marrow area0.40.84.2-0.80.7-1.5-1.8-0.20.2-0.1-0.10.10.1-0.30.2-0.7-0.5-0.4-0.90.9-1.6-2.10.6-0.8
Bone: maximum diameter0.50.83.8-1.51.4-1.9-1.90.1-0.70.30.3-0.3-0.30.4-0.1-0.00.10.2-0.30.1-0.8-1.9-0.1-0.6
Bone: maximum force0.10.21.8-0.50.40.20.40.6-0.60.30.1-0.1-0.10.0-0.4-0.10.70.40.40.21.30.1-0.10.5
Bone: maximum moment0.10.21.3-0.60.5-0.00.20.4-0.60.30.1-0.1-0.10.1-0.3-0.10.60.40.40.11.2-0.1-0.10.4
Mean time between licks in bursts0.81.910.3-1.51.5-2.7-2.90.0-0.70.90.8-0.8-0.80.9-0.30.5-0.10.3-0.3-0.4-3.2-1.9-0.5-0.6
Mean num. licks in bursts1.93.05.3-2.12.1-2.2-2.11.6-1.61.71.9-1.9-1.92.0-1.81.91.41.51.2-1.3-2.3-0.4-1.20.5
Cd content in liver1.61.82.91.2-1.20.70.5-1.31.4-1.4-1.51.51.5-1.61.4-1.7-1.3-1.6-1.41.60.7-1.21.6-1.2
Co content in liver0.30.31.4-0.50.4-1.0-1.10.1-0.00.20.1-0.1-0.10.3-0.0-0.2-0.2-0.3-0.40.5-1.2-1.00.4-0.9
Cu content in liver1.01.22.20.5-0.5-0.6-0.9-1.21.0-1.0-0.90.90.9-0.81.1-1.1-1.4-1.3-1.41.1-1.5-1.40.9-1.4
Fe content in liver0.10.10.50.1-0.10.10.30.2-0.0-0.3-0.30.30.3-0.2-0.0-0.20.0-0.2-0.00.20.70.20.2-0.0
K content in liver0.10.10.90.4-0.40.30.3-0.10.3-0.2-0.10.10.10.1-0.1-0.0-0.3-0.1-0.10.0-1.00.7-0.2-0.4
Mg content in liver0.30.31.0-0.30.4-0.4-0.30.4-0.40.50.6-0.6-0.60.7-0.60.50.30.50.5-0.4-1.00.7-0.70.3
Mn content in liver0.50.53.10.4-0.41.01.20.5-0.30.30.2-0.2-0.20.3-0.50.60.50.50.8-0.60.91.8-0.70.9
Na content in liver1.51.63.4-1.21.3-0.9-0.60.9-1.51.31.4-1.4-1.41.5-1.11.41.11.61.3-1.6-0.90.8-1.81.0
Rb content in liver0.10.10.60.0-0.0-0.1-0.2-0.40.3-0.3-0.30.30.3-0.20.2-0.2-0.4-0.2-0.40.1-0.7-0.20.2-0.4
Se content in liver2.22.69.02.3-2.32.73.0-0.71.4-1.4-1.51.51.5-1.50.9-1.3-0.9-1.1-0.51.02.31.60.80.0
Sr content in liver0.20.20.4-0.50.5-0.20.00.6-0.50.50.5-0.5-0.50.4-0.50.50.70.40.5-0.30.4-0.2-0.20.5
Zn content in liver0.80.85.1-0.90.9-1.9-2.0-0.3-0.20.30.3-0.3-0.30.4-0.00.0-0.4-0.1-0.50.1-2.3-1.3-0.0-0.8
Bone: minimum diameter1.11.97.20.3-0.4-0.6-0.9-1.31.1-1.2-1.31.31.3-1.21.3-1.6-1.5-1.4-1.81.7-0.4-2.71.5-1.9
Time in familiar zone, hab. session 10.10.10.30.3-0.30.20.10.20.4-0.3-0.10.10.1-0.4-0.0-0.4-0.1-0.3-0.10.6-0.2-0.20.5-0.1
Time in novel zone, hab. session 10.40.40.80.4-0.40.20.1-0.90.5-0.7-0.80.80.8-0.50.8-0.6-0.8-0.6-0.80.30.4-0.60.4-0.7
Total zone transitions, hab. session 10.60.92.7-0.60.70.00.3-0.0-1.10.80.7-0.7-0.70.9-0.21.00.81.31.0-1.71.20.9-1.61.0
Total locomotion distance, hab. session 13.14.411.92.0-1.81.20.9-3.41.9-2.3-2.52.52.5-2.03.2-2.1-2.8-1.8-2.40.81.4-1.30.7-1.8
Locomotion velocity, hab. session 12.33.310.01.7-1.51.00.7-3.21.5-1.9-2.12.12.1-1.62.9-1.7-2.5-1.4-2.10.51.4-1.10.4-1.5
Time in familiar zone, hab. session 20.50.53.1-0.80.7-1.1-1.40.6-0.20.20.5-0.5-0.50.4-0.50.40.10.2-0.20.0-1.8-1.20.1-0.4
Time in novel zone, hab. session 20.10.10.90.2-0.20.30.6-0.0-0.00.0-0.10.10.1-0.1-0.0-0.20.2-0.20.30.10.90.90.10.3
Total zone transitions, hab. session 21.41.84.7-1.31.4-0.9-0.50.0-1.71.41.2-1.2-1.21.5-0.41.51.21.71.4-2.21.10.9-2.11.3
Total locomotion distance, hab. session 21.82.38.51.2-1.00.40.3-2.91.1-1.5-1.81.81.8-1.22.6-1.4-2.1-1.2-1.80.31.3-1.10.2-1.4
Locomotion velocity, hab. session 22.02.79.71.3-1.20.40.3-3.11.2-1.7-1.91.91.9-1.32.8-1.6-2.3-1.3-1.90.41.3-1.10.3-1.5
Novel to familiar place preference ratio0.20.20.7-0.40.4-0.2-0.0-0.4-0.60.30.2-0.2-0.20.10.30.10.20.50.4-0.50.90.1-0.80.7
Novelty place preference0.10.10.3-0.30.3-0.2-0.0-0.2-0.40.20.1-0.1-0.10.10.10.00.20.30.3-0.30.50.1-0.50.5
Time in novel zone, NPP test0.10.10.3-0.50.5-0.4-0.20.1-0.60.40.3-0.3-0.30.3-0.10.20.40.40.4-0.30.30.1-0.50.5
Total zone transitions, NPP test0.50.71.5-0.60.6-0.10.10.8-0.90.90.8-0.8-0.80.8-0.90.91.10.91.2-1.00.51.2-0.91.0
Total locomotion distance, NPP test2.23.05.91.8-1.71.00.8-2.41.6-2.0-2.12.12.1-1.82.3-1.9-2.1-1.8-1.81.11.3-0.41.0-1.3
Locomotion velocity, NPP test2.73.87.82.1-2.01.31.0-2.81.8-2.2-2.42.42.4-2.02.7-2.1-2.3-2.0-2.01.21.7-0.31.1-1.4
Intraocular pressure1.52.18.4-1.41.2-1.3-0.22.9-1.21.71.6-1.6-1.61.2-2.31.42.11.01.6-0.2-0.90.5-0.11.2
Delta distance traveled before/after self-admin1.21.33.5-0.80.9-0.5-0.20.6-1.41.31.1-1.1-1.10.8-0.51.20.91.51.2-1.6-0.11.1-1.91.7
Delta ambulatory time before/after self-admin1.11.33.2-0.80.9-0.5-0.10.7-1.41.31.2-1.2-1.20.9-0.61.21.01.51.3-1.60.21.2-1.81.7
Parametrial fat weight0.81.86.91.0-0.91.00.7-2.60.7-1.4-1.61.61.6-1.42.2-1.3-1.4-0.8-1.1-0.12.2-0.80.2-0.6
Pavlov. Cond. lever latency0.60.73.50.9-0.91.11.1-1.10.6-0.7-0.80.80.8-0.91.2-0.8-0.6-0.4-0.40.21.90.30.10.1
Pavlov. Cond. magazine entry latency0.91.13.4-1.61.6-1.9-1.80.6-1.20.90.8-0.8-0.81.0-0.70.70.50.70.3-0.7-1.3-1.3-0.6-0.2
Pavlov. Cond. change in total contacts0.30.40.9-0.80.7-0.9-0.70.9-0.60.60.6-0.6-0.60.5-1.00.50.60.20.3-0.0-1.0-0.10.00.1
Pavlov. Cond. index score0.70.93.9-1.21.1-1.6-1.70.8-0.70.60.7-0.7-0.70.8-0.90.60.30.30.0-0.1-2.0-1.1-0.1-0.4
Pavlov. Cond. latency score0.60.83.0-1.21.2-1.6-1.60.7-0.70.70.7-0.7-0.70.8-0.80.60.40.40.1-0.3-1.7-1.0-0.2-0.4
Pavlov. Cond. lever contacts0.40.43.5-0.60.5-0.9-1.00.8-0.20.40.5-0.5-0.50.5-0.90.40.20.0-0.00.2-1.9-0.60.2-0.5
Pavlov. Cond. magazine entry number0.81.13.61.5-1.51.91.8-0.71.0-0.8-0.80.80.8-0.90.8-0.6-0.4-0.5-0.20.41.61.30.40.2
Pavlov. Cond. intertrial magazine entries1.01.22.61.6-1.61.41.2-0.91.4-1.2-1.01.01.0-1.20.9-1.0-1.0-1.1-0.81.00.40.50.9-0.4
Pavlov. Cond. lever-magazine prob. diff.0.60.83.7-1.11.0-1.4-1.40.9-0.60.70.7-0.7-0.70.8-1.00.60.40.30.1-0.1-1.9-0.9-0.0-0.4
Pavlov. Cond. response bias0.30.42.7-0.70.6-1.0-1.00.7-0.30.40.4-0.4-0.40.5-0.80.30.20.1-0.00.1-1.6-0.70.1-0.4
Pavlov. Cond. lever latency13.017.634.15.8-5.85.85.5-3.05.0-4.5-4.44.44.4-4.63.4-4.0-3.7-4.0-3.13.52.91.03.5-2.0
Pavlov. Cond. magazine entry latency4.55.59.6-3.13.0-2.5-2.22.4-2.82.72.6-2.6-2.62.6-2.42.42.62.32.2-1.9-0.70.4-1.71.4
Pavlov. Cond. change in total contacts6.610.622.6-4.64.6-4.7-4.62.0-4.03.43.3-3.3-3.33.6-2.43.12.73.02.4-2.9-2.1-0.9-2.81.4
Pavlov. Cond. index score9.612.925.1-5.04.9-4.9-4.62.8-4.33.93.8-3.8-3.84.0-3.13.53.33.32.8-2.9-2.2-0.6-2.81.6
Pavlov. Cond. latency score9.112.123.0-4.84.7-4.6-4.32.8-4.23.83.7-3.7-3.73.9-3.13.43.33.32.8-2.8-1.9-0.4-2.81.7
Pavlov. Cond. lever contacts11.515.831.9-5.65.5-5.6-5.42.7-4.74.24.2-4.2-4.24.3-3.13.73.43.72.9-3.3-2.8-1.1-3.31.8
Pavlov. Cond. magazine entry number5.66.912.43.5-3.33.22.9-3.22.9-2.9-2.92.92.9-2.83.2-2.5-2.9-2.1-2.31.31.80.01.2-1.3
Pavlov. Cond. intertrial magazine entries1.01.54.00.6-0.5-0.3-0.6-2.01.0-1.2-1.21.21.2-0.91.8-1.1-1.8-1.0-1.70.5-0.7-2.00.3-1.4
Pavlov. Cond. lever-magazine prob. diff.8.811.723.0-4.84.7-4.7-4.52.7-4.13.73.6-3.6-3.63.8-2.93.33.13.12.6-2.7-2.1-0.7-2.61.5
Pavlov. Cond. response bias11.916.131.7-5.65.5-5.6-5.33.2-4.74.34.2-4.2-4.24.4-3.53.83.63.73.0-3.1-2.9-1.0-3.11.8
Time in closed arm before self-admin0.91.22.2-1.01.0-0.6-0.41.3-1.11.21.0-1.0-1.00.9-1.31.11.21.31.2-0.8-0.60.9-1.31.5
Time in closed arm after self-admin0.50.52.10.4-0.51.01.31.40.30.10.1-0.1-0.10.4-1.40.50.80.20.80.20.61.30.30.1
Time in open arm before self-admin1.51.72.81.7-1.71.61.4-1.41.3-1.5-1.41.41.4-1.40.9-1.4-1.2-1.3-1.01.01.00.31.0-0.7
Time in open arm after self-admin0.40.52.0-0.10.2-0.6-0.9-1.40.2-0.4-0.40.40.4-0.21.2-0.4-0.9-0.4-0.9-0.1-0.1-1.30.2-0.9
Bone: periosteal estimation0.40.95.0-0.80.7-1.5-1.6-0.30.2-0.3-0.40.40.4-0.60.3-1.1-0.5-0.7-1.01.3-0.8-2.21.0-0.9
Bone: periosteal perimeter0.40.74.4-1.01.0-1.7-1.8-0.1-0.10.10.1-0.1-0.10.10.1-0.2-0.3-0.1-0.60.5-1.3-2.10.3-0.8
Bone: post-yield work0.10.21.1-0.50.6-0.2-0.0-0.1-0.60.30.2-0.2-0.20.50.20.30.20.60.2-0.61.0-0.2-0.6-0.0
Progressive ratio test 1 active lever presses0.30.30.9-0.20.20.30.61.0-0.40.50.4-0.4-0.40.9-0.60.80.80.60.8-0.50.80.8-0.30.2
Progressive ratio test 1 breakpoint0.30.30.9-0.20.20.30.50.9-0.40.50.4-0.4-0.40.8-0.60.80.80.60.8-0.50.80.7-0.30.2
Progressive ratio test 1 inactive lever presses0.20.31.80.3-0.31.01.10.6-0.10.10.3-0.3-0.30.5-0.00.40.40.40.5-0.41.41.0-0.40.2
Progressive ratio test 2 active lever presses0.50.51.2-1.00.9-1.1-1.01.0-0.60.70.7-0.7-0.71.0-0.80.70.70.30.4-0.3-0.7-0.60.1-0.4
Progressive ratio test 2 breakpoint0.50.61.2-1.00.9-1.1-1.01.1-0.60.70.7-0.7-0.71.0-0.90.80.80.30.4-0.3-0.7-0.50.1-0.3
Progressive ratio test 2 inactive lever presses0.20.42.1-0.50.5-0.5-0.40.9-0.40.50.5-0.5-0.51.5-0.60.90.40.30.3-0.50.3-0.2-0.0-1.1
Incentive Sensitization - Responses0.70.93.1-1.31.2-1.7-1.50.8-0.70.81.0-1.0-1.00.6-1.10.50.60.40.3-0.3-1.8-1.0-0.10.1
Incentive Sensitization - Breakpoint0.70.93.0-1.31.2-1.6-1.50.8-0.70.81.0-1.0-1.00.7-1.20.50.60.40.3-0.3-1.7-0.9-0.10.1
Sum of active levers in priming session hrs 5-60.20.20.9-0.20.3-0.4-0.5-0.7-0.40.20.2-0.2-0.20.40.60.5-0.10.30.2-1.00.30.2-0.70.2
Progressive ratio0.40.61.7-0.90.8-0.4-0.11.3-0.80.90.8-0.8-0.80.6-1.10.71.30.71.0-0.3-0.20.8-0.30.9
Food seeking constrained by brief footshock1.01.24.4-1.51.6-2.0-2.1-0.8-1.10.90.8-0.8-0.81.10.30.80.10.90.2-1.2-0.7-1.4-1.2-0.0
Seeking ratio, punishment vs. effort0.50.83.6-0.20.3-1.1-1.4-1.70.0-0.3-0.30.30.30.11.2-0.2-1.3-0.2-1.0-0.5-0.5-1.9-0.5-1.1
Retroperitoneal fat weight5.423.241.64.1-4.02.71.0-6.44.7-5.6-5.85.85.8-5.26.0-5.6-5.8-5.0-5.63.81.7-3.83.9-4.6
Reaction time number correct0.51.03.3-0.50.60.20.30.2-1.00.80.8-0.8-0.81.1-0.11.20.81.41.2-1.60.81.3-1.81.1
Reaction time mean minus median0.20.62.7-1.11.1-1.1-1.6-0.2-0.60.40.5-0.5-0.50.7-0.70.50.00.4-0.1-0.4-1.3-1.2-0.5-0.3
Reaction time mean minus median AUC0.41.02.6-1.41.4-1.0-1.60.1-1.10.80.9-0.9-0.91.2-0.81.10.51.00.5-1.1-0.8-0.6-1.10.2
Reaction time num false alarms2.43.45.22.1-2.21.51.7-1.32.2-1.9-2.02.02.0-2.32.0-2.1-1.7-2.0-1.72.01.5-0.31.9-1.1
Reaction time num false alarms AUC1.01.62.91.5-1.61.01.3-0.51.6-1.2-1.31.31.3-1.61.0-1.5-1.0-1.5-1.11.70.80.11.5-0.6
Reaction time trials correct on left0.51.03.3-0.50.60.20.30.2-1.00.80.8-0.8-0.81.1-0.11.20.81.41.2-1.60.81.3-1.81.1
Reaction time trials on left0.61.03.4-0.50.70.20.30.2-1.10.90.9-0.9-0.91.2-0.11.20.81.41.2-1.70.71.3-1.81.1
Reaction time mean0.20.31.00.5-0.50.20.1-1.00.5-0.6-0.60.60.6-0.40.3-0.4-0.7-0.6-0.70.30.4-0.50.5-0.7
Reaction time mean AUC0.20.30.60.7-0.70.50.5-0.80.6-0.6-0.60.60.6-0.50.1-0.4-0.6-0.7-0.60.40.5-0.20.7-0.6
Median of all reaction times0.30.40.80.8-0.80.60.7-0.90.6-0.6-0.70.70.7-0.60.4-0.5-0.7-0.7-0.60.40.80.00.7-0.6
Reaction time omissions0.10.10.8-0.20.2-0.6-0.5-0.10.1-0.1-0.10.10.1-0.1-0.5-0.2-0.3-0.4-0.40.4-0.6-0.90.3-0.4
Reaction time false alarm rate1.82.55.41.7-1.81.11.3-0.52.0-1.5-1.61.61.6-2.11.0-2.0-1.2-2.0-1.52.30.8-0.42.3-1.0
Reaction time premature initiation rate1.01.36.9-0.30.3-0.9-1.6-1.50.3-0.8-0.90.90.9-0.41.0-0.8-1.5-0.8-1.70.5-0.9-2.60.5-1.8
Reaction time premature initiations0.30.52.9-0.70.8-0.9-1.4-1.0-0.4-0.1-0.20.20.20.30.6-0.0-0.80.1-0.8-0.4-0.5-1.7-0.6-0.9
Std. dev. reaction times0.20.52.4-0.30.3-0.7-1.2-0.80.2-0.4-0.30.30.3-0.1-0.2-0.3-0.7-0.5-0.80.4-1.0-1.50.5-1.0
Reaction time trials completed0.61.03.4-0.50.70.20.30.2-1.10.90.9-0.9-0.91.2-0.11.20.81.41.2-1.70.71.3-1.81.1
Reaction time trials AUC0.40.93.1-0.50.70.10.1-0.0-1.00.80.7-0.7-0.71.10.11.10.71.31.1-1.60.81.1-1.80.9
Run reversals in cocaine runway, females3.03.04.81.2-1.30.5-0.1-1.51.6-1.7-1.81.81.8-1.81.4-2.1-1.9-2.1-2.22.2-0.5-2.22.2-2.1
Run reversals in cocaine runway, males0.50.52.5-0.50.40.20.21.6-0.50.60.6-0.6-0.60.9-1.01.01.10.40.9-0.2-0.20.70.20.0
Latency to leave start box in cocaine runway1.71.93.41.8-1.81.81.6-1.31.7-1.6-1.41.41.4-1.21.7-1.1-1.3-1.2-1.00.91.40.80.8-0.6
Latency to leave start box in cocaine runway, F2.52.84.72.0-2.01.61.4-1.62.0-2.0-1.81.81.8-1.82.2-1.7-1.8-1.7-1.61.61.0-0.01.3-1.0
Latency to leave start box in cocaine runway, M0.20.21.30.2-0.20.70.70.40.00.10.2-0.2-0.20.4-0.30.40.40.30.5-0.40.61.2-0.30.4
Std. dev. time between licks in bursts0.60.83.3-0.20.3-1.3-1.5-1.40.2-0.2-0.40.40.4-0.11.3-0.6-1.2-0.4-1.10.1-1.1-1.8-0.1-1.1
Total sessions with >9 infusions1.51.92.9-1.71.7-1.3-1.31.6-1.61.61.5-1.5-1.50.9-1.41.11.41.41.2-0.7-1.60.1-1.11.5
Short access day 1 total inactive lever presses0.30.41.1-0.40.4-0.4-0.31.1-0.80.80.9-0.9-0.91.0-0.80.80.70.30.6-0.3-0.00.40.1-0.2
Short access day 10 total inactive lever presses0.40.92.61.4-1.31.61.6-0.90.9-0.9-0.60.60.6-0.60.9-0.6-0.8-0.6-0.50.31.50.90.2-0.4
Short access day 1 total infusions1.62.24.1-2.01.9-1.9-2.01.4-1.81.71.6-1.6-1.61.1-1.31.11.21.21.0-0.8-2.0-0.7-0.90.9
Short access day 10 total infusions0.60.81.5-1.21.1-1.1-1.01.2-1.01.00.8-0.8-0.80.8-1.20.81.00.70.8-0.4-1.0-0.1-0.30.4
Short access total infusions1.72.13.9-1.81.7-1.4-1.32.0-1.71.71.6-1.6-1.61.1-1.71.31.51.31.3-0.8-1.60.1-0.91.3
Short access day 1 locomotion3.34.15.9-2.42.3-1.6-1.32.2-2.42.42.3-2.3-2.32.0-2.32.12.32.22.0-1.6-1.30.7-1.71.7
Short access day 10 total locomotion0.71.22.4-1.41.4-1.5-1.31.1-1.01.01.2-1.2-1.21.2-1.40.90.91.00.8-0.5-1.5-0.2-0.80.5
Short access total locomotion1.21.52.1-1.31.3-0.8-0.51.1-1.41.41.4-1.4-1.41.1-1.31.21.21.41.2-1.1-0.80.7-1.31.3
One hour access (0.3 mA shock)0.60.71.3-1.11.1-1.1-1.11.0-0.70.80.6-0.6-0.61.1-1.10.80.70.60.5-0.4-1.0-0.4-0.3-0.1
Compulsive drug intake0.20.21.30.3-0.20.50.8-0.1-0.20.10.2-0.2-0.2-0.1-0.10.10.20.40.4-0.40.61.1-0.61.0
One hour access (shock baseline)1.11.73.1-1.71.6-1.4-1.41.7-1.31.41.2-1.2-1.21.8-1.71.61.31.11.1-1.0-1.2-0.1-0.60.1
Social response proportion0.80.91.71.1-1.01.20.5-1.30.9-1.2-1.11.11.1-0.81.2-0.7-1.3-0.7-0.90.10.7-0.20.1-0.7
Social responses1.82.33.81.5-1.51.20.5-1.91.6-1.8-1.71.71.7-1.71.5-1.7-2.0-1.6-1.81.20.3-1.31.1-1.3
Social time1.41.94.62.0-1.92.22.1-1.31.4-1.6-1.41.41.4-1.50.7-1.3-1.1-1.1-0.70.80.91.00.60.1
Soleus weight1.23.76.41.5-1.50.5-0.3-2.21.9-2.0-2.12.12.1-1.92.2-2.1-2.5-2.2-2.51.8-0.4-2.11.9-2.2
Bone: stiffness0.30.54.30.3-0.30.91.1-0.2-0.1-0.5-0.70.70.7-0.60.5-0.7-0.0-0.1-0.10.32.10.20.10.3
Tibialis anterior weight0.10.31.0-0.00.1-0.4-0.5-1.00.1-0.4-0.50.50.5-0.31.0-0.4-0.8-0.3-0.70.00.4-1.00.1-0.7
Time to tail flick, vehicle, before self-admin0.30.31.40.2-0.20.20.00.00.4-0.3-0.10.10.1-1.2-0.2-0.9-0.3-0.4-0.51.0-1.1-0.60.50.4
Time to tail flick, vehicle, after self-admin0.81.02.6-1.21.2-1.2-1.11.2-1.21.11.2-1.2-1.20.3-1.00.60.80.90.7-0.3-1.6-0.3-0.71.1
Time to tail flick, test, before self-admin0.50.51.6-0.1-0.0-0.3-0.7-0.60.5-0.6-0.90.90.9-0.40.7-0.6-0.4-0.7-0.70.60.4-1.21.1-1.3
Time to tail flick, test, after self-admin0.40.41.10.2-0.2-0.4-0.7-0.40.6-0.5-0.40.40.4-0.70.8-0.7-0.6-0.8-0.80.7-0.5-1.00.9-0.9
Delta time to tail flick, vehicle, before/after SA1.81.72.8-1.41.4-1.2-0.91.3-1.71.51.5-1.5-1.51.4-1.31.51.31.41.3-1.3-0.70.5-1.31.0
Delta time to tail flick, test, before/after SA0.10.10.50.5-0.50.50.6-0.30.2-0.10.2-0.2-0.2-0.10.40.1-0.20.00.1-0.30.20.7-0.40.4
Tibia length1.13.15.1-2.22.2-1.6-1.41.0-2.31.91.9-1.9-1.92.0-1.22.01.82.01.7-2.20.00.4-2.01.4
Ambulatory time before self-admin0.20.31.30.6-0.60.91.10.00.5-0.2-0.00.00.0-0.40.3-0.20.2-0.20.20.30.80.80.30.6
Ambulatory time after self-admin0.70.83.60.2-0.10.81.20.2-0.60.60.7-0.7-0.70.10.00.60.70.91.1-1.01.01.9-1.11.7
Bone: tissue strength0.80.85.40.1-0.01.21.50.0-0.70.30.1-0.1-0.10.40.00.40.61.00.8-1.02.31.4-1.21.1
Total heroin consumption0.10.10.50.1-0.10.30.0-0.4-0.1-0.2-0.20.20.20.10.50.2-0.0-0.10.0-0.50.70.3-0.0-0.0
Bone: trabecular number0.50.93.31.1-1.11.71.80.20.9-0.9-0.90.90.9-1.00.0-0.8-0.3-0.6-0.41.01.30.40.9-0.3
Bone: trabecular spacing1.21.72.6-1.41.5-1.5-1.40.5-1.41.51.5-1.5-1.51.5-0.71.51.11.31.2-1.6-0.60.3-1.50.9
Bone: trabecular thickness1.11.32.41.0-1.10.80.5-0.81.2-1.3-1.21.21.2-1.41.0-1.4-1.2-1.3-1.31.50.3-1.31.5-1.1
Bone: trabecular tissue density1.62.37.71.6-1.51.10.8-2.81.3-1.6-1.71.71.7-1.52.5-1.5-1.9-1.3-1.50.51.5-0.50.5-0.9
Water consumed over 24 hours0.40.51.11.0-1.01.11.0-0.30.8-0.8-0.70.70.7-0.70.5-0.8-0.6-0.6-0.50.80.40.20.5-0.4
Number of responses in last shaping day2.73.04.21.8-1.81.30.9-1.81.7-2.0-1.81.81.8-1.52.0-1.8-2.0-2.0-2.01.60.9-1.11.8-2.1