Hub : Traits

Short access day 1 total inactive lever presses

Tags: Behavior · Cocaine · Short access

Project: p50_paul_meyer_2020

6 loci · 6 genes with independent associations · 6 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr1	88613126	89913275	1	1	4.94e-08	1.09e-01	1.93e-03	Zfp575
2	chr4	97220462	98544003	1	1	1.48e-10	3.49e-01	1.00e+00	Il12rb2
3	chr7	92127461	93066096	1	1	2.15e-10	3.03e-01	1.00e+00	Ndufb9
4	chr8	117463629	118343328	1	1	1.20e-21	2.69e-01	1.00e+00	Mst1
5	chr9	83390749	84777604	1	1	0.00e+00	3.05e-01	1.00e+00	Retreg2
6	chr17	61510864	62906219	1	1	5.33e-08	2.20e-02	1.00e+00	Ccny

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	1286.39	3	3	50	0	1.00e+00	Il12rb2 Ndufb9 Retreg2
BMI without tail	36009.96	4	3	50	-1	7.77e-04	Ccny Il12rb2 Ndufb9 Retreg2
Body weight	8.23	3	2	33.3	0	1.00e+00	Mst1 Ndufb9 Retreg2
Epididymis fat weight	27130.87	4	3	50	-1	1.02e-03	Ccny Mst1 Ndufb9 Retreg2
Glucose	825.95	3	2	33.3	0	1.00e+00	Mst1 Ndufb9 Retreg2
Heart weight	3384.98	4	2	33.3	1	4.53e-04	Ccny Il12rb2 Ndufb9 Retreg2
Left kidney weight	35317.46	4	2	33.3	1	1.83e-04	Ccny Il12rb2 Ndufb9 Retreg2
Right kidney weight	29220.21	4	4	66.7	1	2.63e-04	Ccny Mst1 Ndufb9 Retreg2
Tail length	30711.52	3	2	33.3	0	1.00e+00	Ccny Mst1 Retreg2
Length with tail	1539.71	4	3	50	-1	4.03e-03	Il12rb2 Mst1 Ndufb9 Retreg2
Length without tail	25869.38	5	3	50	1	1.18e-05	Ccny Mst1 Ndufb9 Retreg2 Zfp575
Liver weight, left	3639.22	4	3	50	1	2.38e-03	Ccny Mst1 Ndufb9 Retreg2
Liver weight, right	75	4	2	33.3	0.9	1.01e-01	Ccny Mst1 Ndufb9 Retreg2
Parametrial fat weight	311.74	2	1	16.7	0	1.00e+00	Ccny Retreg2
Retroperitoneal fat weight	5360.92	3	2	33.3	0	1.00e+00	Il12rb2 Mst1 Retreg2
Intraocular pressure	40071.91	1	1	16.7	0	1.00e+00	Retreg2
Extensor digitorum longus weight	2342.82	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Soleus weight	40.94	3	1	16.7	0	1.00e+00	Ccny Ndufb9 Retreg2
Tibialis anterior weight	4881.94	1	1	16.7	0	1.00e+00	Retreg2
Tibia length	1094.3	3	2	33.3	0	1.00e+00	Mst1 Ndufb9 Retreg2
Number of licking bursts	78561.42	2	1	16.7	0	1.00e+00	Ccny Retreg2
Food consumed during 24 hour testing period	35405.04	3	1	16.7	0	1.00e+00	Ccny Mst1 Retreg2
Times rat made contact with spout	158.46	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Mean time between licks in bursts	66503.89	3	1	16.7	0	1.00e+00	Ccny Ndufb9 Retreg2
Mean num. licks in bursts	71302.54	2	1	16.7	0	1.00e+00	Ccny Retreg2
Std. dev. time between licks in bursts	47023.49	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Water consumed over 24 hours	51711.02	2	1	16.7	0	1.00e+00	Ccny Retreg2
Patch foraging indifference point 0 sec	38345.93	3	2	33.3	0	1.00e+00	Il12rb2 Mst1 Retreg2
Patch foraging indifference point AUC	33311.57	4	3	50	1	1.75e-04	Ccny Mst1 Ndufb9 Retreg2
Indifference point function ln k	35546.2	4	4	66.7	-1	2.30e-04	Ccny Mst1 Ndufb9 Retreg2
Indifference point function log k	35546.2	4	4	66.7	-1	2.30e-04	Ccny Mst1 Ndufb9 Retreg2
Patch foraging total patch changes 0 sec	40098.74	3	2	33.3	0	1.00e+00	Il12rb2 Mst1 Retreg2
Patch foraging total patch changes 12 sec	2774.7	4	4	66.7	-1	1.93e-03	Ccny Mst1 Ndufb9 Retreg2
Patch foraging total patch changes 18 sec	29448.67	4	1	16.7	-1	4.31e-04	Ccny Mst1 Ndufb9 Retreg2
Patch foraging total patch changes 24 sec	33436.09	5	4	66.7	-1	4.66e-06	Ccny Il12rb2 Mst1 Ndufb9 Retreg2
Patch foraging total patch changes 6 sec	8184.96	4	4	66.7	-1	7.14e-04	Ccny Il12rb2 Ndufb9 Retreg2
Patch foraging time to switch 0 sec	52210.5	3	2	33.3	0	1.00e+00	Mst1 Ndufb9 Retreg2
Patch foraging water rate 0 sec	74407.03	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 12 sec	53969.51	3	2	33.3	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging water rate 18 sec	20659.52	5	1	16.7	1	1.01e-05	Ccny Il12rb2 Mst1 Ndufb9 Retreg2
Patch foraging water rate 24 sec	1575.07	3	2	33.3	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging water rate 6 sec	1363.06	3	3	50	0	1.00e+00	Ccny Ndufb9 Retreg2
Locomotor activity	24.47	4	2	33.3	-0.5	5.01e-01	Ccny Il12rb2 Mst1 Retreg2
Locomotor testing distance	17918.05	5	3	50	1	4.04e-05	Ccny Il12rb2 Mst1 Ndufb9 Retreg2
Locomotor testing rearing	38108.59	4	2	33.3	1	5.09e-04	Il12rb2 Mst1 Ndufb9 Retreg2
Light reinforcement 1	77669.42	2	2	33.3	0	1.00e+00	Ccny Retreg2
Light reinforcement 2	21616.85	5	3	50	1	4.39e-05	Ccny Il12rb2 Mst1 Ndufb9 Retreg2
Reaction time number correct	51168.28	3	3	50	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time mean minus median	51454.06	4	1	16.7	-1	3.65e-04	Ccny Mst1 Ndufb9 Retreg2
Reaction time mean minus median AUC	69469.62	3	3	50	0	1.00e+00	Mst1 Ndufb9 Retreg2
Reaction time num false alarms	19041.41	3	2	33.3	0	1.00e+00	Ccny Mst1 Retreg2
Reaction time num false alarms AUC	35512.53	3	2	33.3	0	1.00e+00	Ccny Mst1 Retreg2
Reaction time trials correct on left	51168.28	3	3	50	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time trials on left	50013.45	3	3	50	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time mean	31463.57	3	1	16.7	0	1.00e+00	Ccny Il12rb2 Retreg2
Reaction time mean AUC	37784.58	3	1	16.7	0	1.00e+00	Ccny Il12rb2 Retreg2
Median of all reaction times	15711.8	2	1	16.7	0	1.00e+00	Il12rb2 Retreg2
Reaction time omissions	17137.2	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Reaction time false alarm rate	302.63	3	1	16.7	0	1.00e+00	Mst1 Ndufb9 Retreg2
Reaction time premature initiation rate	18442.81	2	1	16.7	0	1.00e+00	Ccny Retreg2
Reaction time premature initiations	69362.16	2	1	16.7	0	1.00e+00	Ccny Retreg2
Std. dev. reaction times	37375.03	4	1	16.7	-1	4.08e-04	Il12rb2 Mst1 Ndufb9 Retreg2
Reaction time trials completed	50013.45	3	3	50	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time trials AUC	50581.81	3	2	33.3	0	1.00e+00	Ccny Ndufb9 Retreg2
Social response proportion	11775.59	3	1	16.7	0	1.00e+00	Il12rb2 Mst1 Retreg2
Social responses	1149.52	5	2	33.3	1	1.04e-05	Ccny Il12rb2 Mst1 Ndufb9 Retreg2
Social time	14749.63	3	1	16.7	0	1.00e+00	Ccny Mst1 Retreg2
Conditioned locomotion	3044.63	2	1	16.7	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. corrected	32913.12	2	1	16.7	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. not corrected	32126.2	2	1	16.7	0	1.00e+00	Ccny Retreg2
Cocaine response before conditioning	942.16	3	1	16.7	0	1.00e+00	Ccny Il12rb2 Retreg2
Saline control response	6522.43	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active minus inactive responses	26712.34	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active-inactive response ratio	45793.79	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active responses	4856.3	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. inactive responses	14046.99	3	2	33.3	0	1.00e+00	Ccny Mst1 Retreg2
Condit. Reinf. lever presses	5308.92	3	2	33.3	0	1.00e+00	Mst1 Ndufb9 Retreg2
Condit. Reinf. lever reinforcers received	1007.39	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever latency	5465.68	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry latency	16518.76	3	2	33.3	0	1.00e+00	Ccny Mst1 Retreg2
Pavlov. Cond. change in total contacts	57393.18	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. index score	16014.27	3	2	33.3	0	1.00e+00	Ccny Mst1 Retreg2
Pavlov. Cond. latency score	19509.23	3	2	33.3	0	1.00e+00	Ccny Mst1 Retreg2
Pavlov. Cond. lever contacts	11053	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry number	8453.95	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	52501.71	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	14975.97	3	2	33.3	0	1.00e+00	Ccny Mst1 Retreg2
Pavlov. Cond. response bias	2629.8	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Conditioned reinforcement - actives	63842.12	3	3	50	0	1.00e+00	Ccny Ndufb9 Retreg2
Conditioned reinforcement - inactives	31027.37	5	4	66.7	-1	6.55e-05	Ccny Il12rb2 Mst1 Ndufb9 Retreg2
Conditioned locomotion	10384.72	4	3	50	-1	1.37e-03	Ccny Mst1 Ndufb9 Retreg2
Intermittent access intake day 1-15 change	52654.67	4	2	33.3	-1	2.75e-05	Ccny Il12rb2 Mst1 Retreg2
Intermittent access intake escalation	104773.43	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation 2	27027.92	4	2	33.3	-1	6.18e-04	Ccny Il12rb2 Mst1 Retreg2
Intermitt. access day 1 inactive lever presses	59140.52	4	2	33.3	-1	6.88e-04	Ccny Mst1 Ndufb9 Retreg2
Intermitt. access day 15 inactive lever presses	104145.18	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Intermitt. access escalation Index	37009.71	5	2	33.3	1	1.70e-05	Ccny Il12rb2 Mst1 Ndufb9 Retreg2
Intermittent access day 1 total infusions	51844.88	3	1	16.7	0	1.00e+00	Ccny Mst1 Retreg2
Intermittent access day 15 total infusions	32877.15	4	1	16.7	-1	6.73e-04	Ccny Il12rb2 Retreg2 Zfp575
Intermittent access terminal intake (last 3 days)	20808.04	4	2	33.3	-1	8.58e-04	Ccny Il12rb2 Retreg2 Zfp575
Intermittent access total infusions	181.92	4	1	16.7	0.96	3.87e-02	Ccny Il12rb2 Retreg2 Zfp575
Intermittent access day 1 locomotion	52247.41	2	2	33.3	0	1.00e+00	Ccny Retreg2
Intermittent access day 15 total locomotion	88947.95	2	2	33.3	0	1.00e+00	Ccny Retreg2
Intermittent access total locomotion	150.29	5	1	16.7	-0.97	7.79e-03	Il12rb2 Mst1 Ndufb9 Retreg2 Zfp575
Intermittent access standard deviation	67321.91	3	3	50	0	1.00e+00	Ccny Mst1 Retreg2
Cocaine induced anxiety	53447.41	3	3	50	0	1.00e+00	Ccny Ndufb9 Retreg2
Post-drug Anxiety	5127.75	4	2	33.3	1	1.22e-03	Il12rb2 Ndufb9 Retreg2 Zfp575
Baseline Anxiety	34558.77	3	3	50	0	1.00e+00	Ccny Ndufb9 Retreg2
Lifetime Intake	1726.64	4	2	33.3	0.99	5.74e-03	Ccny Il12rb2 Retreg2 Zfp575
Incentive Sensitization - Responses	40906.23	4	4	66.7	1	2.57e-04	Ccny Ndufb9 Retreg2 Zfp575
Incentive Sensitization - Breakpoint	35709.45	4	4	66.7	1	2.74e-04	Ccny Ndufb9 Retreg2 Zfp575
Progressive ratio test 1 active lever presses	33313.84	3	2	33.3	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio test 1 breakpoint	32105.23	3	2	33.3	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio test 1 inactive lever presses	30229.43	5	4	66.7	-1	3.91e-05	Ccny Il12rb2 Mst1 Ndufb9 Retreg2
Progressive ratio test 2 active lever presses	14320.69	4	2	33.3	1	7.08e-04	Ccny Ndufb9 Retreg2 Zfp575
Progressive ratio test 2 breakpoint	11684.3	3	2	33.3	0	1.00e+00	Ccny Retreg2 Zfp575
Progressive ratio test 2 inactive lever presses	41031.87	4	2	33.3	-1	3.66e-04	Ccny Mst1 Ndufb9 Retreg2
Total sessions with >9 infusions	1619.72	5	3	50	0.99	1.07e-03	Ccny Il12rb2 Mst1 Retreg2 Zfp575
Short access day 10 total inactive lever presses	54316.81	4	3	50	-1	5.56e-04	Ccny Il12rb2 Mst1 Retreg2
Short access day 1 total infusions	22352.41	5	3	50	1	7.66e-05	Ccny Il12rb2 Mst1 Retreg2 Zfp575
Short access day 10 total infusions	19085.03	4	3	50	1	1.51e-04	Ccny Mst1 Ndufb9 Retreg2
Short access total infusions	11354.15	3	2	33.3	0	1.00e+00	Ccny Il12rb2 Retreg2
Short access day 1 locomotion	21036.75	4	3	50	-1	1.15e-04	Ccny Ndufb9 Retreg2 Zfp575
Short access day 10 total locomotion	60537.65	3	2	33.3	0	1.00e+00	Ccny Mst1 Retreg2
Short access total locomotion	22764.96	3	2	33.3	0	1.00e+00	Mst1 Ndufb9 Retreg2
Compulsive drug intake	10913.48	6	1	16.7	1	1.36e-06	Ccny Il12rb2 Mst1 Ndufb9 Retreg2 Zfp575
One hour access (0.3 mA shock)	1953.13	5	3	50	-0.99	5.32e-04	Ccny Il12rb2 Ndufb9 Retreg2 Zfp575
One hour access (shock baseline)	46759.84	3	1	16.7	0	1.00e+00	Ccny Retreg2 Zfp575
Number of responses in last shaping day	12861.35	4	2	33.3	-1	2.59e-03	Ccny Il12rb2 Retreg2 Zfp575
Context. condit. distance diff. score	970.59	1	1	16.7	0	1.00e+00	Retreg2
Locomotion velocity, session 1	4880.23	3	1	16.7	0	1.00e+00	Il12rb2 Ndufb9 Retreg2
Locomotion distance, session 1	1479.21	3	1	16.7	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion velocity, session 2	4702.2	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 2	609.18	4	1	16.7	-0.99	1.07e-02	Ccny Il12rb2 Mst1 Retreg2
Locomotion velocity, session 3	2332.53	1	1	16.7	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	16.7	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	2943.11	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving duration, day 3	6074.03	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, session 7	708.6	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 7	1294.52	3	2	33.3	0	1.00e+00	Mst1 Ndufb9 Retreg2
Stereotopy head waving bouts, day 7	5257.18	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving duration, day 7	4446.48	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Locomotion velocity, session 8	950.4	2	1	16.7	0	1.00e+00	Ccny Retreg2
Locomotion distance, session 8	673.32	1	1	16.7	0	1.00e+00	Retreg2
Degree of sensitization distance	7696.03	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Degree of sensitization stereotypy	2841.03	3	1	16.7	0	1.00e+00	Mst1 Ndufb9 Retreg2
Condit. Reinf. active minus inactive responses	2066.34	2	1	16.7	0	1.00e+00	Ccny Retreg2
Condit. Reinf. active-inactive response ratio	1097.66	1	1	16.7	0	1.00e+00	Retreg2
Condit. Reinf. active responses	5839.15	2	1	16.7	0	1.00e+00	Ccny Retreg2
Condit. Reinf. inactive responses	6466.37	3	1	16.7	0	1.00e+00	Mst1 Ndufb9 Retreg2
Incentive salience index mean	4936.47	3	1	16.7	0	1.00e+00	Ccny Mst1 Retreg2
Condit. Reinf. lever presses	10735.09	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Time in familiar zone, hab. session 1	20942.14	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 1	17770.84	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 1	916.07	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 1	567.95	3	1	16.7	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion velocity, hab. session 1	383.06	3	1	16.7	0	1.00e+00	Ccny Il12rb2 Retreg2
Time in familiar zone, hab. session 2	11707.23	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 2	12499.19	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 2	76.33	4	1	16.7	1	1.30e-03	Il12rb2 Mst1 Ndufb9 Retreg2
Total locomotion distance, hab. session 2	51.92	2	1	16.7	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 2	53.75	3	1	16.7	0	1.00e+00	Ccny Il12rb2 Retreg2
Novel to familiar place preference ratio	18511.87	3	1	16.7	0	1.00e+00	Ccny Mst1 Retreg2
Novelty place preference	18137	3	1	16.7	0	1.00e+00	Ccny Mst1 Retreg2
Time in novel zone, NPP test	20429.72	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Total zone transitions, NPP test	2754.49	3	2	33.3	0	1.00e+00	Il12rb2 Ndufb9 Retreg2
Total locomotion distance, NPP test	2380.74	3	2	33.3	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion velocity, NPP test	1357.92	3	2	33.3	0	1.00e+00	Ccny Il12rb2 Retreg2
Pavlov. Cond. lever latency	748.85	3	2	33.3	0	1.00e+00	Il12rb2 Mst1 Retreg2
Pavlov. Cond. magazine entry latency	8.04	1	0	0	0	1.00e+00	Ccny
Pavlov. Cond. change in total contacts	2273.55	2	1	16.7	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. index score	899.58	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	935.96	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever contacts	774.23	4	2	33.3	0.99	1.15e-02	Il12rb2 Mst1 Ndufb9 Retreg2
Pavlov. Cond. magazine entry number	726.35	3	1	16.7	0	1.00e+00	Ccny Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	190.08	3	2	33.3	0	1.00e+00	Mst1 Ndufb9 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	979.4	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	1310.66	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Bone: apparent density	11138.75	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Bone surface	12570.47	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Bone volume	16919.6	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Bone: connectivity density	2373.11	3	1	16.7	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: cortical apparent density	15092.86	3	1	16.7	0	1.00e+00	Ccny Ndufb9 Retreg2
Bone: cortical area	6332.51	3	2	33.3	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: cortical porosity	618.67	3	1	16.7	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: cortical porosity	1607.32	3	1	16.7	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: cortical thickness	566.34	3	2	33.3	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: cortical thickness	4081.28	3	2	33.3	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: cortical tissue density	16155.62	3	1	16.7	0	1.00e+00	Ccny Ndufb9 Retreg2
Bone: elastic displacement	29626.25	1	1	16.7	0	1.00e+00	Retreg2
Bone: elastic work	757.88	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Bone: endosteal estimation	11756.25	3	1	16.7	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: endosteal perimeter	22351.85	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Bone: final force	3544.85	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Bone: final moment	548.75	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Bone: marrow area	12360.31	3	1	16.7	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: maximum diameter	8150.69	3	2	33.3	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: maximum force	17305.93	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Bone: maximum moment	12386.14	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Bone: minimum diameter	8606.13	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Bone: periosteal estimation	19111.51	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Bone: periosteal perimeter	21606.9	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Bone: post-yield work	25428.45	2	1	16.7	0	1.00e+00	Mst1 Retreg2
Bone: stiffness	17808.98	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Bone: tissue strength	12264.67	1	1	16.7	0	1.00e+00	Retreg2
Bone: trabecular number	20584.56	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular spacing	10445.17	3	3	50	0	1.00e+00	Mst1 Ndufb9 Retreg2
Bone: trabecular thickness	16647.3	2	2	33.3	0	1.00e+00	Mst1 Retreg2
Bone: trabecular tissue density	13418.39	4	4	66.7	-1	6.92e-04	Ccny Mst1 Ndufb9 Retreg2
Breakpoint value in progressive ratio session	37483.32	3	1	16.7	0	1.00e+00	Ccny Mst1 Retreg2
Distance traveled before self-admin	26818.88	5	2	33.3	-1	3.46e-05	Ccny Il12rb2 Ndufb9 Retreg2 Zfp575
Distance traveled after self-admin	33647.86	3	2	33.3	0	1.00e+00	Ccny Retreg2 Zfp575
Delta time in closed arm before/after self-admin	519.4	4	2	33.3	-0.89	1.13e-01	Ccny Il12rb2 Ndufb9 Retreg2
Delta time in open arm before/after self-admin	27441.91	2	2	33.3	0	1.00e+00	Ccny Retreg2
Diff in mean of infusions in LGA sessions	36170.06	3	1	16.7	0	1.00e+00	Mst1 Ndufb9 Retreg2
Extinction: sum of active levers before priming	18365.54	5	4	66.7	-1	3.32e-05	Ccny Il12rb2 Mst1 Ndufb9 Retreg2
Active lever presses in extinction session 6	845.39	4	2	33.3	0.98	2.43e-02	Ccny Il12rb2 Mst1 Retreg2
Delta distance traveled before/after self-admin	3156.41	4	3	50	0.99	1.18e-02	Ccny Il12rb2 Ndufb9 Retreg2
Delta ambulatory time before/after self-admin	24031.75	4	3	50	1	1.23e-03	Ccny Il12rb2 Ndufb9 Retreg2
Time in closed arm before self-admin	22082.6	4	4	66.7	1	4.25e-05	Ccny Il12rb2 Mst1 Retreg2
Time in closed arm after self-admin	6616.57	3	3	50	0	1.00e+00	Ccny Mst1 Retreg2
Time in open arm before self-admin	5804.5	6	3	50	1	9.95e-06	Ccny Il12rb2 Mst1 Ndufb9 Retreg2 Zfp575
Time in open arm after self-admin	417.22	5	4	66.7	-0.93	2.01e-02	Ccny Il12rb2 Mst1 Ndufb9 Retreg2
Sum of active levers in priming session hrs 5-6	1318.66	3	2	33.3	0	1.00e+00	Il12rb2 Ndufb9 Retreg2
Time to tail flick, vehicle, before self-admin	10382.69	5	3	50	-1	2.99e-04	Ccny Il12rb2 Mst1 Ndufb9 Retreg2
Time to tail flick, vehicle, after self-admin	29584.01	4	2	33.3	-1	9.08e-05	Ccny Ndufb9 Retreg2 Zfp575
Time to tail flick, test, before self-admin	8217.57	4	2	33.3	1	4.03e-04	Ccny Mst1 Ndufb9 Retreg2
Time to tail flick, test, after self-admin	2022.59	3	3	50	0	1.00e+00	Ccny Ndufb9 Retreg2
Delta time to tail flick, vehicle, before/after SA	9237.32	4	3	50	-1	3.07e-03	Ccny Il12rb2 Mst1 Retreg2
Delta time to tail flick, test, before/after SA	14216.41	4	1	16.7	-1	1.04e-03	Ccny Mst1 Ndufb9 Retreg2
Ambulatory time before self-admin	57050.88	3	2	33.3	0	1.00e+00	Ccny Il12rb2 Retreg2
Ambulatory time after self-admin	29437.11	3	2	33.3	0	1.00e+00	Ccny Mst1 Retreg2
Total heroin consumption	370.93	3	2	33.3	0	1.00e+00	Ccny Il12rb2 Retreg2
Area under the delay curve	40810.48	2	1	16.7	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 0s delay	4741.82	2	1	16.7	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 16s delay	37437.33	2	2	33.3	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 2s delay	416.46	2	1	16.7	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 24s delay	50025	2	2	33.3	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 4s delay	870.6	3	2	33.3	0	1.00e+00	Ccny Ndufb9 Retreg2
Delay disc. indifference point, 8s delay	101423.99	1	1	16.7	0	1.00e+00	Retreg2
Delay discount exponential model param	30110.07	2	1	16.7	0	1.00e+00	Ccny Retreg2
Delay discount hyperbolic model param	45715.54	1	1	16.7	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	75084.64	2	1	16.7	0	1.00e+00	Ccny Retreg2
Change in fecal boli incidents, locomotor task	7889.79	3	3	50	0	1.00e+00	Ccny Ndufb9 Retreg2
Time >=10cm from walls, locomotor time 1	12336.02	4	3	50	1	7.73e-05	Ccny Il12rb2 Ndufb9 Retreg2
Bouts of movement, locomotor time 1	13900.93	3	2	33.3	0	1.00e+00	Ccny Il12rb2 Retreg2
Total resting periods, locomotor time 1	3964.11	3	2	33.3	0	1.00e+00	Ccny Il12rb2 Retreg2
Rest time, locomotor task time 1	18996.78	4	1	16.7	-1	1.15e-03	Ccny Il12rb2 Ndufb9 Retreg2
Distance moved, locomotor task time 1	39837	4	3	50	1	1.11e-03	Ccny Il12rb2 Ndufb9 Retreg2
Vertical activity count, locomotor time 1	73022	3	1	16.7	0	1.00e+00	Il12rb2 Retreg2 Zfp575
Time >=10cm from walls, locomotor time 2	54000.88	3	2	33.3	0	1.00e+00	Ccny Il12rb2 Retreg2
Bouts of movement, locomotor time 2	58112.08	3	2	33.3	0	1.00e+00	Ccny Il12rb2 Retreg2
Total resting periods, locomotor time 2	63369.04	3	2	33.3	0	1.00e+00	Ccny Il12rb2 Retreg2
Rest time, locomotor task time 2	27936.17	3	2	33.3	0	1.00e+00	Ccny Ndufb9 Retreg2
Distance moved, locomotor task time 2	17217.33	2	2	33.3	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 2	69238.05	2	2	33.3	0	1.00e+00	Ccny Retreg2
Weight adjusted by age	40521.16	4	3	50	-1	1.22e-03	Ccny Ndufb9 Retreg2 Zfp575
Seeking ratio, delayed vs. immediate footshock	16476.57	3	2	33.3	0	1.00e+00	Ccny Retreg2 Zfp575
Locomotion in novel chamber	4103.82	4	3	50	1	1.92e-03	Ccny Il12rb2 Ndufb9 Retreg2
Locomotion in novel chamber post-restriction	51551.01	3	1	16.7	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio	52658.05	3	3	50	0	1.00e+00	Ccny Ndufb9 Retreg2
Food seeking constrained by brief footshock	1841.15	4	1	16.7	1	1.70e-03	Il12rb2 Ndufb9 Retreg2 Zfp575
Seeking ratio, punishment vs. effort	29579.4	4	3	50	-1	9.54e-04	Ccny Il12rb2 Ndufb9 Retreg2
Run reversals in cocaine runway, females	18598.36	2	1	16.7	0	1.00e+00	Ccny Retreg2
Run reversals in cocaine runway, males	9993.2	3	2	33.3	0	1.00e+00	Ccny Ndufb9 Retreg2
Latency to leave start box in cocaine runway	29317.55	2	2	33.3	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway, F	14201.52	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Latency to leave start box in cocaine runway, M	1844.99	4	2	33.3	0.99	8.69e-03	Ccny Ndufb9 Retreg2 Zfp575
Co content in liver	4721.74	1	1	16.7	0	1.00e+00	Retreg2
Cu content in liver	89.33	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Fe content in liver	5656.2	1	1	16.7	0	1.00e+00	Retreg2
K content in liver	6593.53	1	1	16.7	0	1.00e+00	Retreg2
Mg content in liver	24493.99	1	1	16.7	0	1.00e+00	Retreg2
Mn content in liver	2219.37	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Na content in liver	8325.4	2	1	16.7	0	1.00e+00	Ndufb9 Retreg2
Rb content in liver	241.33	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2
Se content in liver	8.64	1	0	0	0	1.00e+00	Ndufb9
Zn content in liver	7891.81	2	2	33.3	0	1.00e+00	Ndufb9 Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.11
Adipose	alternative TSS	0	0	1.13
Adipose	gene expression	0	0	1.11
Adipose	isoform ratio	0	0	1.1
Adipose	intron excision ratio	0	0	1.21
Adipose	mRNA stability	1	0	1.12
BLA	alternative polyA	0	0	1.15
BLA	alternative TSS	0	0	1.03
BLA	gene expression	0	0	1.11
BLA	isoform ratio	0	0	1.16
BLA	intron excision ratio	0	0	1.1
BLA	mRNA stability	0	0	1.12
Brain	alternative polyA	0	0	1.14
Brain	alternative TSS	0	0	1
Brain	gene expression	0	0	1.1
Brain	isoform ratio	0	0	1.1
Brain	intron excision ratio	0	0	1.1
Brain	mRNA stability	0	0	1.1
Eye	alternative polyA	0	0	1.16
Eye	alternative TSS	0	0	0.97
Eye	gene expression	0	0	1.16
Eye	isoform ratio	0	0	1.29
Eye	intron excision ratio	0	0	0.96
Eye	mRNA stability	0	0	1.14
IC	alternative polyA	0	0	1.15
IC	alternative TSS	0	0	1.06
IC	gene expression	0	0	1.13
IC	isoform ratio	0	0	1.15
IC	intron excision ratio	0	0	1.12
IC	mRNA stability	0	0	1.11
IL	alternative polyA	0	0	1.22
IL	alternative TSS	0	0	0.89
IL	gene expression	0	0	1.11
IL	isoform ratio	0	0	1.17
IL	intron excision ratio	0	0	1.01
IL	mRNA stability	0	0	1.12
LHb	alternative polyA	0	0	1.27
LHb	alternative TSS	0	0	0.97
LHb	gene expression	0	0	1.09
LHb	isoform ratio	0	0	1.15
LHb	intron excision ratio	0	0	0.97
LHb	mRNA stability	0	0	1.2
Liver	alternative polyA	0	0	1.06
Liver	alternative TSS	0	0	1.07
Liver	gene expression	0	0	1.12
Liver	isoform ratio	1	0	1.17
Liver	intron excision ratio	0	0	1.07
Liver	mRNA stability	0	0	1.16
NAcc	alternative polyA	2	0.1	64.94
NAcc	alternative TSS	0	0	1.11
NAcc	gene expression	0	0	1.12
NAcc	isoform ratio	0	0	1.15
NAcc	intron excision ratio	0	0	1.12
NAcc	mRNA stability	0	0	1.15
OFC	alternative polyA	0	0	1.11
OFC	alternative TSS	0	0	1.03
OFC	gene expression	0	0	1.11
OFC	isoform ratio	0	0	1.1
OFC	intron excision ratio	0	0	0.96
OFC	mRNA stability	0	0	1.11
PL	alternative polyA	0	0	1.22
PL	alternative TSS	0	0	1.05
PL	gene expression	0	0	1.11
PL	isoform ratio	0	0	1.12
PL	intron excision ratio	0	0	1.13
PL	mRNA stability	1	0	1.15
pVTA	alternative polyA	0	0	1.19
pVTA	alternative TSS	0	0	1.11
pVTA	gene expression	1	0	1.11
pVTA	isoform ratio	0	0	1.15
pVTA	intron excision ratio	0	0	1.11
pVTA	mRNA stability	0	0	1.14
RMTg	alternative polyA	0	0	1.2
RMTg	alternative TSS	0	0	1.14
RMTg	gene expression	0	0	1.16
RMTg	isoform ratio	0	0	1.21
RMTg	intron excision ratio	0	0	0.94
RMTg	mRNA stability	0	0	1.14