Hub : Genes

LOC120099891

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC120099891 0.06 0.05 1.4e-04 0.05 0.05 0.05 0.04 5.4e-05 7.6e-05 8.2e-05 1.7e-04
2 NAcc intron excision ratio chr1_162948977_162957777 0.2 0.1 0.0e+00 0.16 0.16 0.16 0.15 7.4e-23 7.8e-23 4.9e-23 2.2e-22
3 PL gene expression LOC120099891 0.07 0.05 3.8e-07 0.03 0.05 0.05 0.05 1.6e-04 3.1e-06 8.3e-06 3.9e-06
4 Brain gene expression LOC120099891 0.28 0.15 3.3e-10 0.09 0.11 0.09 0.1 9.4e-09 4.0e-10 2.4e-08 1.7e-09
5 BLA gene expression LOC120099891 0.31 0.16 7.0e-08 0.06 0.1 0.08 0.1 3.3e-04 9.0e-06 6.2e-05 7.3e-06
6 NAcc intron excision ratio chr1_162984434_162985025 0.21 0.09 0.0e+00 0.15 0.2 0.2 0.2 1.9e-22 2.5e-29 1.7e-29 1.2e-29
7 NAcc gene expression LOC120099891 0.15 0.09 0.0e+00 0.08 0.13 0.13 0.13 2.6e-12 1.5e-18 5.5e-19 5.3e-19
8 Adipose gene expression LOC120099891 0.11 0.06 1.3e-12 0.09 0.08 0.08 0.08 8.7e-10 5.1e-09 1.8e-09 3.8e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.10.20.60.0-0.60.20.80.40.30.40.6
Area under the delay curve0.00.00.00.10.1-0.0-0.20.10.1-0.1-0.2
BMI with tail0.41.43.00.6-0.31.00.91.31.21.61.7
BMI without tail1.75.18.31.5-1.62.22.12.42.52.72.9
Body weight1.04.27.61.2-1.01.91.82.32.22.62.8
Weight adjusted by age0.40.70.80.7-0.70.90.70.80.90.90.9
Bone surface2.44.46.72.0-2.32.12.62.22.01.81.8
Bone volume1.52.74.01.3-1.91.62.01.71.61.51.6
Breakpoint value in progressive ratio session1.61.92.4-1.21.4-1.4-1.6-1.4-1.4-1.3-1.3
Number of licking bursts1.42.34.9-2.22.2-1.7-1.5-1.3-1.3-0.6-0.0
Context. condit. distance diff. score1.41.73.92.0-1.91.31.61.10.90.3-0.3
Locomotion velocity, session 11.92.03.0-1.31.0-1.4-1.7-1.6-1.4-1.5-1.5
Locomotion distance, session 10.30.41.10.20.0-0.3-0.7-0.5-0.7-1.0-1.1
Locomotion velocity, session 20.10.10.3-0.30.1-0.1-0.6-0.20.00.0-0.0
Locomotion distance, session 20.00.00.10.2-0.30.1-0.3-0.10.0-0.2-0.4
Locomotion velocity, session 30.20.31.10.4-0.0-0.1-0.2-0.3-0.4-0.8-1.1
Locomotion distance, session 30.40.41.40.4-0.2-0.2-0.3-0.4-0.5-1.0-1.2
Stereotopy head waving bouts, day 30.10.10.2-0.50.2-0.1-0.20.00.10.40.5
Stereotopy head waving duration, day 30.10.10.30.5-0.50.40.50.30.30.1-0.1
Locomotion velocity, session 70.50.60.8-0.40.9-0.7-0.6-0.7-0.8-0.9-0.8
Locomotion distance, session 70.00.10.1-0.10.4-0.2-0.1-0.1-0.2-0.2-0.3
Stereotopy head waving bouts, day 70.40.51.31.1-1.00.80.50.50.50.0-0.4
Stereotopy head waving duration, day 71.11.32.51.6-1.51.41.21.11.00.60.3
Locomotion velocity, session 81.31.52.51.5-1.61.31.61.21.10.80.4
Locomotion distance, session 80.60.92.31.5-1.51.00.80.80.70.2-0.4
Degree of sensitization distance1.01.02.20.1-0.20.70.91.01.01.51.5
Degree of sensitization stereotypy0.91.02.81.7-1.41.20.80.80.70.1-0.3
Conditioned locomotion0.40.40.7-0.40.3-0.6-0.6-0.7-0.7-0.8-0.8
Cocaine response after cond. corrected1.01.22.9-1.41.7-1.1-1.2-0.9-1.0-0.4-0.2
Cocaine response after cond. not corrected0.70.81.7-0.91.3-0.9-1.0-0.8-1.0-0.6-0.5
Cocaine response before conditioning0.30.41.20.9-1.10.60.50.40.3-0.2-0.3
Saline control response1.31.72.41.6-1.31.41.31.51.31.01.0
Bone: connectivity density0.40.61.70.7-1.00.61.30.70.60.50.6
Bone: cortical apparent density0.40.61.7-1.31.0-0.8-0.7-0.6-0.40.10.3
Bone: cortical area1.11.82.61.2-1.21.31.61.51.31.21.3
Bone: cortical porosity0.40.41.50.30.0-0.3-0.5-0.5-0.6-1.0-1.2
Bone: cortical porosity0.30.41.30.2-0.2-0.3-0.5-0.5-0.5-0.9-1.1
Bone: cortical thickness0.10.20.3-0.50.5-0.5-0.3-0.4-0.5-0.4-0.2
Bone: cortical thickness0.00.00.10.2-0.0-0.0-0.1-0.0-0.2-0.3-0.3
Bone: cortical tissue density0.50.71.9-1.41.1-0.9-0.8-0.7-0.5-0.10.1
Condit. Reinf. active minus inactive responses1.01.11.40.7-1.11.01.01.11.21.21.1
Condit. Reinf. active-inactive response ratio2.72.93.51.3-1.71.71.91.81.81.81.6
Condit. Reinf. active responses0.10.20.30.1-0.40.30.20.40.50.50.6
Condit. Reinf. inactive responses0.50.61.1-0.70.6-0.7-1.0-0.8-0.6-0.8-0.6
Incentive salience index mean0.70.91.10.6-1.00.90.80.91.11.11.0
Condit. Reinf. lever presses0.20.30.40.4-0.60.60.30.50.60.50.5
Condit. Reinf. active minus inactive responses4.86.210.43.2-2.52.92.52.72.41.71.5
Condit. Reinf. active-inactive response ratio0.30.31.11.1-0.50.70.40.70.50.10.1
Condit. Reinf. active responses8.511.816.54.1-3.43.93.53.83.42.72.5
Condit. Reinf. inactive responses6.58.49.92.9-3.03.13.03.03.02.62.4
Condit. Reinf. lever presses13.518.630.85.5-4.74.84.84.54.12.92.2
Condit. Reinf. lever reinforcers received8.812.217.94.2-3.54.03.63.83.42.72.3
Conditioned reinforcement - actives0.20.41.11.0-0.90.60.70.40.3-0.1-0.3
Conditioned reinforcement - inactives0.60.91.5-0.91.2-1.0-1.0-0.9-1.0-0.9-0.7
Conditioned locomotion0.50.62.30.5-0.3-0.3-0.2-0.5-0.7-1.1-1.5
Patch foraging indifference point 0 sec3.56.510.73.3-2.92.82.92.62.41.71.1
Patch foraging indifference point AUC0.81.11.80.8-0.71.00.91.21.11.31.3
Delay disc. indifference point, 0s delay0.30.30.70.6-0.90.80.30.30.70.50.1
Delay disc. indifference point, 16s delay0.20.20.3-0.30.5-0.5-0.4-0.3-0.4-0.6-0.5
Delay disc. indifference point, 2s delay0.30.30.80.9-0.50.70.30.50.60.2-0.1
Delay disc. indifference point, 24s delay0.30.30.7-0.80.8-0.7-0.4-0.3-0.5-0.10.2
Delay disc. indifference point, 4s delay0.20.20.40.4-0.50.5-0.20.40.70.40.3
Delay disc. indifference point, 8s delay0.30.30.60.8-0.50.50.60.70.60.40.2
Indifference point function ln k0.20.41.50.7-0.70.10.2-0.2-0.2-0.9-1.2
Indifference point function log k0.20.41.50.7-0.70.10.2-0.2-0.2-0.9-1.2
Patch foraging total patch changes 0 sec2.95.59.13.0-2.62.62.72.42.21.61.0
Patch foraging total patch changes 12 sec3.54.55.22.0-2.12.22.22.32.12.11.9
Patch foraging total patch changes 18 sec3.75.66.52.3-2.52.52.42.42.42.31.9
Patch foraging total patch changes 24 sec0.30.50.80.6-0.50.90.50.70.70.80.6
Patch foraging total patch changes 6 sec1.21.83.11.8-1.41.41.71.41.10.80.6
Patch foraging time to switch 0 sec3.06.18.5-2.92.7-2.7-2.7-2.6-2.4-1.9-1.5
Patch foraging water rate 0 sec1.73.66.22.5-2.22.12.02.01.71.20.8
Patch foraging water rate 12 sec0.40.92.41.5-1.21.11.00.90.70.1-0.0
Patch foraging water rate 18 sec0.40.60.80.9-0.90.90.70.80.70.40.5
Patch foraging water rate 24 sec0.20.31.00.7-0.60.10.0-0.1-0.3-0.8-1.0
Patch foraging water rate 6 sec0.10.20.50.7-0.60.40.50.30.2-0.2-0.3
Seeking ratio, delayed vs. immediate footshock1.92.33.6-1.91.5-1.6-1.6-1.6-1.5-1.2-0.8
Distance traveled before self-admin0.10.10.3-0.40.5-0.4-0.2-0.1-0.20.0-0.0
Distance traveled after self-admin2.83.53.9-1.61.7-2.0-1.9-1.9-2.0-1.9-1.9
Extensor digitorum longus weight0.62.24.60.7-0.71.21.51.61.61.82.2
Bone: elastic displacement1.41.72.5-1.31.6-1.4-1.0-1.3-1.4-1.1-1.0
Bone: elastic work1.51.92.7-1.51.6-1.6-1.1-1.4-1.5-1.2-1.1
Bone: endosteal estimation2.96.37.12.2-2.42.62.52.72.72.62.4
Bone: endosteal perimeter3.47.28.02.6-2.82.82.72.82.82.62.3
Epididymis fat weight0.10.51.6-0.91.3-0.6-0.8-0.5-0.6-0.2-0.1
Delta time in closed arm before/after self-admin0.50.41.4-0.30.30.20.30.50.61.11.2
Delta time in open arm before/after self-admin3.03.03.81.9-2.01.91.91.81.71.31.3
Diff in mean of infusions in LGA sessions5.16.28.3-2.92.9-2.7-2.9-2.5-2.4-1.8-1.5
Delay discount exponential model param0.00.00.1-0.1-0.20.10.3-0.0-0.00.10.2
Extinction: sum of active levers before priming0.00.00.1-0.00.20.1-0.10.10.10.10.3
Active lever presses in extinction session 61.21.14.30.60.1-0.5-0.5-0.7-1.0-1.6-2.1
Bone: final force0.10.10.40.3-0.30.20.70.40.20.20.3
Bone: final moment0.20.40.90.5-0.60.50.90.70.50.50.5
Food consumed during 24 hour testing period1.01.43.71.4-1.91.31.01.01.20.60.3
Glucose0.00.00.1-0.10.3-0.1-0.1-0.1-0.1-0.0-0.0
Heart weight0.50.81.61.3-1.00.91.21.00.70.50.4
Delay discount hyperbolic model param0.00.00.1-0.2-0.0-0.10.1-0.2-0.3-0.1-0.0
Intermittent access intake day 1-15 change0.20.31.01.0-0.80.50.60.40.3-0.2-0.5
Intermittent access intake escalation0.20.41.21.1-0.90.60.70.40.3-0.1-0.4
Intermittent access intake escalation 20.40.51.21.1-0.80.70.80.60.50.1-0.1
Intermitt. access day 1 inactive lever presses0.72.64.4-1.82.1-1.7-1.8-1.5-1.5-1.1-0.8
Intermitt. access day 15 inactive lever presses1.42.93.8-1.82.0-1.8-1.8-1.7-1.7-1.5-1.2
Intermitt. access escalation Index0.00.00.10.1-0.10.10.30.20.10.20.2
Intermittent access day 1 total infusions0.30.50.80.9-0.80.80.90.70.60.40.2
Intermittent access day 15 total infusions0.40.61.41.2-1.00.81.00.60.50.1-0.3
Intermittent access terminal intake (last 3 days)0.91.22.31.5-1.41.21.41.00.90.50.1
Intermittent access total infusions1.01.21.91.3-1.31.21.41.11.00.70.5
Intermittent access day 1 locomotion0.00.10.20.3-0.40.10.40.10.0-0.1-0.2
Intermittent access day 15 total locomotion0.20.30.80.9-0.70.30.60.20.0-0.4-0.7
Intermittent access total locomotion0.30.40.70.9-0.80.60.80.50.40.20.0
Intermittent access standard deviation0.51.01.30.8-0.81.01.01.11.11.21.1
Left kidney weight0.62.74.21.0-1.21.61.21.71.92.02.1
Right kidney weight0.93.96.11.2-1.51.91.62.12.22.42.5
Cocaine induced anxiety0.30.41.0-1.00.8-0.8-0.5-0.6-0.6-0.20.1
Post-drug Anxiety0.40.41.1-1.10.9-0.8-0.5-0.6-0.5-0.20.1
Baseline Anxiety0.20.20.30.5-0.50.50.50.50.50.40.4
Tail length2.18.313.11.8-2.32.82.63.03.13.43.6
Length with tail1.14.77.11.4-1.52.11.92.42.32.62.7
Length without tail0.20.50.9-0.80.9-0.7-0.9-0.6-0.6-0.4-0.4
Times rat made contact with spout0.40.51.6-0.1-0.20.50.50.60.81.01.3
Lifetime Intake0.91.01.81.4-1.31.11.21.00.90.60.3
Liver weight, left0.30.51.7-0.00.00.50.30.70.71.11.3
Liver weight, right0.50.83.1-1.00.60.0-0.30.30.61.21.7
Locomotor activity1.01.52.61.3-1.61.21.31.31.30.60.8
Locomotor testing distance2.13.75.02.0-2.22.11.92.02.11.51.5
Locomotor testing rearing1.22.43.01.3-1.51.61.41.71.71.51.6
Locomotion in novel chamber0.20.20.50.6-0.70.20.40.10.1-0.6-0.7
Locomotion in novel chamber post-restriction0.40.72.31.5-0.80.70.70.50.3-0.6-0.8
Fecal boli incidents, locomotor time 10.10.10.40.4-0.60.10.20.1-0.0-0.5-0.4
Change in fecal boli incidents, locomotor task0.70.71.5-0.91.2-0.9-0.8-0.8-0.9-0.4-0.6
Time >=10cm from walls, locomotor time 10.30.31.01.0-0.60.40.50.20.1-0.4-0.8
Bouts of movement, locomotor time 10.00.00.1-0.10.3-0.1-0.3-0.2-0.2-0.2-0.2
Total resting periods, locomotor time 10.30.30.5-0.50.6-0.5-0.5-0.7-0.7-0.5-0.7
Rest time, locomotor task time 11.01.21.6-0.91.0-1.1-1.3-1.1-1.2-1.0-1.2
Distance moved, locomotor task time 11.72.53.21.3-1.51.51.81.71.71.61.7
Vertical activity count, locomotor time 11.22.94.01.7-1.71.72.01.81.81.51.5
Time >=10cm from walls, locomotor time 20.20.30.60.7-0.80.70.30.40.40.40.1
Bouts of movement, locomotor time 20.20.30.50.5-0.30.70.40.40.50.60.4
Total resting periods, locomotor time 20.00.00.10.20.10.40.00.10.20.30.1
Rest time, locomotor task time 21.21.52.6-1.61.5-1.4-1.1-1.2-1.2-0.8-0.5
Distance moved, locomotor task time 22.02.33.41.8-1.81.71.41.51.51.30.9
Vertical activity count, locomotor time 22.02.73.31.7-1.81.71.71.71.71.51.3
Light reinforcement 10.40.92.4-1.51.3-1.1-1.0-0.9-0.6-0.40.1
Light reinforcement 20.20.20.3-0.50.5-0.5-0.5-0.5-0.5-0.6-0.5
Bone: marrow area2.75.96.62.1-2.32.52.52.62.62.62.3
Bone: maximum diameter3.36.17.72.6-2.52.62.82.72.42.21.9
Bone: maximum force0.20.41.10.7-0.60.61.10.70.50.50.5
Bone: maximum moment0.50.81.70.9-0.90.81.31.00.80.70.7
Mean time between licks in bursts2.86.98.32.4-2.52.92.32.82.82.72.5
Mean num. licks in bursts1.82.95.12.2-2.31.91.81.61.60.90.5
Cd content in liver0.10.10.3-0.20.30.0-0.00.10.20.50.6
Co content in liver1.51.72.11.2-1.41.41.11.31.51.41.1
Cu content in liver0.50.61.30.2-0.50.80.00.71.01.11.1
Fe content in liver0.10.10.2-0.10.4-0.3-0.2-0.2-0.3-0.3-0.1
K content in liver0.10.10.2-0.30.0-0.0-0.4-0.10.20.20.3
Mg content in liver0.10.10.2-0.0-0.0-0.0-0.4-0.2-0.1-0.3-0.4
Mn content in liver2.62.93.5-1.51.5-1.8-1.7-1.8-1.8-1.9-1.7
Na content in liver0.10.10.30.5-0.40.2-0.10.00.0-0.3-0.5
Rb content in liver0.91.01.51.0-1.21.01.11.01.10.90.8
Se content in liver7.28.511.4-3.23.1-3.2-3.4-3.0-2.9-2.5-1.9
Sr content in liver0.10.10.30.2-0.1-0.1-0.1-0.2-0.2-0.4-0.6
Zn content in liver2.32.53.31.7-1.81.81.31.61.71.41.2
Bone: minimum diameter2.54.66.81.4-1.72.02.12.32.32.52.6
Time in familiar zone, hab. session 10.10.10.3-0.2-0.20.20.10.20.40.50.4
Time in novel zone, hab. session 10.00.00.1-0.10.4-0.10.1-0.0-0.1-0.00.2
Total zone transitions, hab. session 10.10.20.60.1-0.1-0.3-0.1-0.3-0.4-0.6-0.7
Total locomotion distance, hab. session 10.20.31.2-0.50.40.0-0.20.20.30.81.1
Locomotion velocity, hab. session 10.10.20.8-0.30.20.1-0.00.30.30.70.9
Time in familiar zone, hab. session 23.23.34.71.6-2.21.82.01.72.01.81.4
Time in novel zone, hab. session 22.32.33.1-1.11.8-1.4-1.7-1.4-1.7-1.6-1.3
Total zone transitions, hab. session 20.20.30.70.9-0.50.30.10.0-0.2-0.6-0.8
Total locomotion distance, hab. session 20.40.61.70.2-0.20.60.30.70.81.11.3
Locomotion velocity, hab. session 20.40.51.90.1-0.10.60.20.70.71.01.4
Novel to familiar place preference ratio0.10.10.2-0.00.5-0.3-0.4-0.3-0.5-0.4-0.4
Novelty place preference0.20.20.4-0.20.6-0.4-0.6-0.4-0.6-0.5-0.5
Time in novel zone, NPP test0.10.10.20.00.4-0.2-0.4-0.3-0.4-0.4-0.4
Total zone transitions, NPP test0.30.40.9-0.20.3-0.5-0.7-0.6-0.7-0.9-0.9
Total locomotion distance, NPP test0.40.61.4-1.11.1-0.6-1.2-0.5-0.5-0.10.3
Locomotion velocity, NPP test0.81.12.3-1.41.5-0.9-1.5-0.8-0.8-0.30.2
Intraocular pressure0.20.30.90.40.1-0.2-0.1-0.3-0.5-0.9-0.9
Delta distance traveled before/after self-admin0.50.51.5-0.1-0.0-0.5-0.6-0.7-0.7-1.1-1.2
Delta ambulatory time before/after self-admin0.60.71.8-0.10.1-0.6-0.7-0.8-0.9-1.3-1.3
Parametrial fat weight0.10.20.7-0.50.8-0.3-0.2-0.1-0.20.20.4
Pavlov. Cond. lever latency1.72.23.4-1.31.8-1.6-1.3-1.4-1.6-1.4-1.2
Pavlov. Cond. magazine entry latency3.74.76.02.4-2.52.42.32.22.11.81.5
Pavlov. Cond. change in total contacts0.60.71.10.9-1.10.90.60.80.80.60.6
Pavlov. Cond. index score3.54.46.12.1-2.52.32.12.12.21.91.6
Pavlov. Cond. latency score3.34.15.92.1-2.42.22.02.02.11.81.5
Pavlov. Cond. lever contacts1.82.13.21.2-1.81.61.31.41.61.51.3
Pavlov. Cond. magazine entry number3.54.46.0-2.32.5-2.3-2.2-2.1-2.1-1.7-1.5
Pavlov. Cond. intertrial magazine entries2.53.04.4-2.01.8-1.8-2.1-1.8-1.6-1.4-1.0
Pavlov. Cond. lever-magazine prob. diff.3.03.75.11.9-2.32.11.91.92.01.81.5
Pavlov. Cond. response bias1.82.23.21.4-1.81.61.41.41.61.41.3
Pavlov. Cond. lever latency12.517.031.3-5.64.6-4.7-4.5-4.3-3.8-2.5-1.7
Pavlov. Cond. magazine entry latency2.83.37.42.7-2.22.02.21.71.40.80.2
Pavlov. Cond. change in total contacts5.89.419.94.5-3.43.53.23.22.71.60.9
Pavlov. Cond. index score8.811.923.54.8-3.93.93.83.53.02.01.1
Pavlov. Cond. latency score7.59.920.44.5-3.53.63.53.22.71.70.9
Pavlov. Cond. lever contacts12.016.530.25.5-4.54.64.54.23.72.51.7
Pavlov. Cond. magazine entry number3.23.99.7-3.12.4-2.3-2.1-1.9-1.5-0.7-0.0
Pavlov. Cond. intertrial magazine entries0.81.22.90.3-0.70.90.81.11.21.51.7
Pavlov. Cond. lever-magazine prob. diff.8.311.121.74.7-3.73.83.73.43.01.91.1
Pavlov. Cond. response bias12.517.031.35.6-4.64.64.64.23.72.51.6
Time in closed arm before self-admin0.20.20.60.4-0.60.10.1-0.2-0.2-0.7-0.8
Time in closed arm after self-admin1.21.31.7-1.31.1-1.2-1.1-1.3-1.2-1.1-0.8
Time in open arm before self-admin1.51.62.6-1.51.6-1.5-1.6-1.2-1.1-0.7-0.7
Time in open arm after self-admin1.71.92.31.3-1.11.31.41.51.41.41.4
Bone: periosteal estimation2.65.46.42.1-2.22.42.52.52.42.32.2
Bone: periosteal perimeter3.45.96.92.2-2.42.52.62.62.52.42.2
Bone: post-yield work1.11.62.81.1-1.31.11.71.21.21.21.2
Progressive ratio test 1 active lever presses0.40.60.8-0.50.6-0.8-0.6-0.8-0.8-0.9-0.8
Progressive ratio test 1 breakpoint0.40.50.7-0.50.6-0.7-0.6-0.8-0.8-0.9-0.8
Progressive ratio test 1 inactive lever presses0.30.50.7-0.60.8-0.7-0.5-0.7-0.7-0.7-0.6
Progressive ratio test 2 active lever presses0.30.40.60.8-0.70.70.80.60.60.40.2
Progressive ratio test 2 breakpoint0.30.40.60.8-0.70.60.80.60.50.40.2
Progressive ratio test 2 inactive lever presses0.10.10.30.5-0.20.30.60.30.1-0.00.0
Incentive Sensitization - Responses1.11.62.21.5-1.31.41.41.31.21.00.8
Incentive Sensitization - Breakpoint1.11.42.01.4-1.21.31.41.21.10.90.7
Sum of active levers in priming session hrs 5-60.10.10.2-0.10.4-0.2-0.4-0.3-0.4-0.3-0.4
Progressive ratio0.00.10.20.4-0.40.10.10.00.0-0.4-0.4
Food seeking constrained by brief footshock1.92.32.91.7-1.51.71.51.71.51.31.2
Seeking ratio, punishment vs. effort1.21.82.51.0-1.01.41.21.41.41.61.5
Retroperitoneal fat weight0.52.18.0-1.01.00.30.41.01.02.12.8
Reaction time number correct0.40.71.5-0.30.2-0.7-0.8-0.8-0.9-1.2-1.1
Reaction time mean minus median0.92.23.11.6-1.51.61.81.61.51.21.2
Reaction time mean minus median AUC0.61.52.31.5-1.41.31.51.31.10.80.7
Reaction time num false alarms0.50.71.8-1.31.1-0.9-1.0-0.7-0.50.00.3
Reaction time num false alarms AUC0.40.71.5-1.21.0-0.9-1.1-0.8-0.6-0.20.0
Reaction time trials correct on left0.40.71.5-0.30.2-0.7-0.8-0.8-0.9-1.2-1.1
Reaction time trials on left0.40.71.5-0.30.3-0.7-0.8-0.8-0.9-1.2-1.2
Reaction time mean0.10.10.4-0.30.6-0.10.30.20.00.40.6
Reaction time mean AUC0.20.31.1-0.81.0-0.5-0.2-0.3-0.4-0.00.3
Median of all reaction times0.30.41.4-0.91.2-0.6-0.2-0.4-0.5-0.00.3
Reaction time omissions0.10.10.20.20.10.30.40.40.30.40.4
Reaction time false alarm rate0.30.51.3-1.11.0-0.6-0.7-0.5-0.30.20.4
Reaction time premature initiation rate5.17.18.52.3-2.32.72.92.92.72.82.7
Reaction time premature initiations2.34.15.22.0-2.02.12.32.22.01.81.8
Std. dev. reaction times1.01.92.41.1-1.01.41.61.51.41.51.5
Reaction time trials completed0.40.71.5-0.30.3-0.7-0.8-0.8-0.9-1.2-1.2
Reaction time trials AUC0.30.51.0-0.20.2-0.6-0.7-0.6-0.8-1.0-1.0
Run reversals in cocaine runway, females2.52.55.70.5-0.81.31.41.61.72.22.4
Run reversals in cocaine runway, males0.00.00.0-0.10.0-0.10.1-0.00.00.00.1
Latency to leave start box in cocaine runway1.61.83.4-1.71.8-1.5-1.7-1.2-1.1-0.7-0.4
Latency to leave start box in cocaine runway, F0.91.02.2-1.41.5-1.0-1.3-0.7-0.5-0.10.2
Latency to leave start box in cocaine runway, M0.80.80.9-0.70.9-0.9-0.9-0.9-0.9-0.9-0.9
Std. dev. time between licks in bursts2.33.24.41.3-1.51.81.41.92.02.11.9
Total sessions with >9 infusions1.11.32.41.5-1.51.31.31.11.10.70.3
Short access day 1 total inactive lever presses0.00.00.1-0.20.3-0.2-0.2-0.2-0.1-0.2-0.1
Short access day 10 total inactive lever presses0.61.31.9-1.31.4-1.2-1.2-1.2-1.1-1.0-0.7
Short access day 1 total infusions2.12.84.02.0-1.91.91.81.71.71.31.0
Short access day 10 total infusions0.60.81.31.1-1.11.00.90.90.80.60.4
Short access total infusions0.91.12.11.4-1.31.21.11.01.00.60.3
Short access day 1 locomotion0.70.92.51.6-1.31.01.10.80.60.1-0.3
Short access day 10 total locomotion0.61.12.01.4-1.41.21.11.00.90.70.3
Short access total locomotion0.20.30.70.8-0.80.50.60.30.30.0-0.3
One hour access (0.3 mA shock)0.60.71.51.2-1.10.91.10.80.60.30.1
Compulsive drug intake1.72.03.1-0.91.1-1.3-1.3-1.4-1.6-1.8-1.7
One hour access (shock baseline)0.71.11.91.4-1.31.21.21.00.90.60.4
Social response proportion0.20.20.5-0.70.6-0.4-0.4-0.2-0.2-0.10.4
Social responses0.20.21.0-0.50.20.1-0.20.20.40.51.0
Social time4.15.67.5-2.52.7-2.5-2.7-2.3-2.4-2.0-1.4
Soleus weight1.23.68.30.6-0.81.61.71.92.02.62.9
Bone: stiffness0.00.10.2-0.20.3-0.10.30.20.10.30.5
Tibialis anterior weight0.41.52.11.0-0.61.21.31.41.31.31.4
Time to tail flick, vehicle, before self-admin0.60.71.20.5-1.10.81.10.60.70.70.9
Time to tail flick, vehicle, after self-admin1.01.31.91.4-1.41.21.41.21.00.80.5
Time to tail flick, test, before self-admin1.61.62.20.9-1.11.21.21.31.41.41.5
Time to tail flick, test, after self-admin0.50.51.00.3-0.30.70.40.70.80.91.0
Delta time to tail flick, vehicle, before/after SA0.20.20.70.8-0.30.30.20.40.2-0.0-0.6
Delta time to tail flick, test, before/after SA1.01.01.4-0.91.2-1.0-1.2-1.0-1.0-0.9-0.8
Tibia length0.30.93.21.8-0.90.80.80.50.1-0.6-1.0
Ambulatory time before self-admin0.61.01.4-0.91.2-1.1-1.0-0.9-1.0-0.8-0.9
Ambulatory time after self-admin3.84.55.5-1.61.8-2.1-2.1-2.2-2.3-2.4-2.3
Bone: tissue strength1.31.32.3-0.60.9-1.1-0.7-1.2-1.4-1.5-1.5
Total heroin consumption0.00.00.1-0.00.0-0.1-0.3-0.0-0.0-0.0-0.1
Bone: trabecular number0.10.20.6-0.80.3-0.60.1-0.4-0.5-0.30.0
Bone: trabecular spacing0.10.20.70.6-0.30.1-0.3-0.1-0.1-0.4-0.8
Bone: trabecular thickness0.30.31.2-0.1-0.00.30.60.50.50.71.1
Bone: trabecular tissue density0.40.61.5-1.21.1-0.7-0.8-0.5-0.30.20.5
Water consumed over 24 hours0.20.30.9-1.00.6-0.6-0.6-0.6-0.3-0.30.0
Number of responses in last shaping day0.40.51.6-0.1-0.20.40.40.60.71.01.3