Hub : Traits

Time in closed arm before self-admin

Time spent in the closed arm during the first time point of elevated plus maze before self admin

Tags: Behavior · Heroin · Elevated plus maze

Project: u01_peter_kalivas

4 loci · 4 genes with independent associations · 4 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr4	97220462	98544003	1	1	1.63e-07	1.28e-01	1.00e+00	Il12rb2
2	chr8	117463629	118343328	1	1	3.26e-12	5.27e-01	1.00e+00	Mst1
3	chr9	83390749	84777604	1	1	0.00e+00	3.18e-02	1.00e+00	Retreg2
4	chr17	61510864	62906219	1	1	1.09e-19	1.10e-02	5.26e-10	Ccny

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	1283	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
BMI without tail	48010.36	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Body weight	5.42	2	1	25	0	1.00e+00	Mst1 Retreg2
Epididymis fat weight	36172.96	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Glucose	1235.87	2	2	50	0	1.00e+00	Mst1 Retreg2
Heart weight	4510.8	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Left kidney weight	47088.15	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Right kidney weight	38957.39	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Tail length	30711.52	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Length with tail	2050	3	2	50	0	1.00e+00	Il12rb2 Mst1 Retreg2
Length without tail	43113.37	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Liver weight, left	4850.01	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Liver weight, right	98.2	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Parametrial fat weight	311.74	2	1	25	0	1.00e+00	Ccny Retreg2
Retroperitoneal fat weight	5360.92	3	2	50	0	1.00e+00	Il12rb2 Mst1 Retreg2
Intraocular pressure	40071.91	1	1	25	0	1.00e+00	Retreg2
Extensor digitorum longus weight	2342.82	2	1	25	0	1.00e+00	Mst1 Retreg2
Soleus weight	59.13	2	1	25	0	1.00e+00	Ccny Retreg2
Tibialis anterior weight	4881.94	1	1	25	0	1.00e+00	Retreg2
Tibia length	1639.71	2	2	50	0	1.00e+00	Mst1 Retreg2
Number of licking bursts	78561.42	2	1	25	0	1.00e+00	Ccny Retreg2
Food consumed during 24 hour testing period	35405.04	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Times rat made contact with spout	305.36	1	1	25	0	1.00e+00	Retreg2
Mean time between licks in bursts	99755.05	2	1	25	0	1.00e+00	Ccny Retreg2
Mean num. licks in bursts	71302.54	2	1	25	0	1.00e+00	Ccny Retreg2
Std. dev. time between licks in bursts	47023.49	2	1	25	0	1.00e+00	Mst1 Retreg2
Water consumed over 24 hours	51711.02	2	1	25	0	1.00e+00	Ccny Retreg2
Patch foraging indifference point 0 sec	38345.93	3	2	50	0	1.00e+00	Il12rb2 Mst1 Retreg2
Patch foraging indifference point AUC	44412.09	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Indifference point function ln k	47383.87	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Indifference point function log k	47383.87	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging total patch changes 0 sec	40098.74	3	2	50	0	1.00e+00	Il12rb2 Mst1 Retreg2
Patch foraging total patch changes 12 sec	3684.52	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging total patch changes 18 sec	39262.24	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging total patch changes 24 sec	41783.21	4	3	75	-1	8.80e-06	Ccny Il12rb2 Mst1 Retreg2
Patch foraging total patch changes 6 sec	8181.7	4	3	75	-1	2.55e-04	Ccny Il12rb2 Mst1 Retreg2
Patch foraging time to switch 0 sec	52207.37	3	1	25	0	1.00e+00	Il12rb2 Mst1 Retreg2
Patch foraging water rate 0 sec	148807.58	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 12 sec	53969.51	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging water rate 18 sec	25823.47	4	1	25	1	2.20e-05	Ccny Il12rb2 Mst1 Retreg2
Patch foraging water rate 24 sec	1575.07	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Patch foraging water rate 6 sec	2028.63	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotor activity	24.47	4	2	50	-0.5	5.05e-01	Ccny Il12rb2 Mst1 Retreg2
Locomotor testing distance	22395.04	4	3	75	1	1.00e-03	Ccny Il12rb2 Mst1 Retreg2
Locomotor testing rearing	50810.6	3	2	50	0	1.00e+00	Il12rb2 Mst1 Retreg2
Light reinforcement 1	77669.42	2	2	50	0	1.00e+00	Ccny Retreg2
Light reinforcement 2	27020.25	4	3	75	1	7.75e-04	Ccny Il12rb2 Mst1 Retreg2
Reaction time number correct	76747.74	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time mean minus median	68604.85	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Reaction time mean minus median AUC	104201.52	2	2	50	0	1.00e+00	Mst1 Retreg2
Reaction time num false alarms	19041.41	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Reaction time num false alarms AUC	35512.53	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Reaction time trials correct on left	76747.74	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time trials on left	75015.72	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time mean	31463.57	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Reaction time mean AUC	37784.58	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Median of all reaction times	15711.8	2	1	25	0	1.00e+00	Il12rb2 Retreg2
Reaction time omissions	34267.91	1	1	25	0	1.00e+00	Retreg2
Reaction time false alarm rate	451.08	2	1	25	0	1.00e+00	Mst1 Retreg2
Reaction time premature initiation rate	18442.81	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time premature initiations	46242.13	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Std. dev. reaction times	37374.78	4	1	25	-1	7.24e-05	Ccny Il12rb2 Mst1 Retreg2
Reaction time trials completed	75015.72	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time trials AUC	75869.15	2	2	50	0	1.00e+00	Ccny Retreg2
Social response proportion	11775.59	3	1	25	0	1.00e+00	Il12rb2 Mst1 Retreg2
Social responses	1435.36	4	2	50	1	4.67e-04	Ccny Il12rb2 Mst1 Retreg2
Social time	14749.63	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Conditioned locomotion	3044.63	2	1	25	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. corrected	32913.12	2	1	25	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. not corrected	32126.2	2	1	25	0	1.00e+00	Ccny Retreg2
Cocaine response before conditioning	942.16	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Saline control response	6522.43	2	2	50	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active minus inactive responses	26712.34	2	1	25	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active-inactive response ratio	91582.24	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	4856.3	2	2	50	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. inactive responses	14046.99	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Condit. Reinf. lever presses	5308.34	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Condit. Reinf. lever reinforcers received	1007.39	2	1	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever latency	5465.68	2	1	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry latency	16518.76	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Pavlov. Cond. change in total contacts	114781.94	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. index score	16014.27	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Pavlov. Cond. latency score	19509.23	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Pavlov. Cond. lever contacts	11053	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. magazine entry number	5637.62	3	2	50	0	1.00e+00	Il12rb2 Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	52501.71	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	14975.97	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Pavlov. Cond. response bias	1754.73	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Conditioned reinforcement - actives	95753.16	2	2	50	0	1.00e+00	Ccny Retreg2
Conditioned reinforcement - inactives	38778.24	4	3	75	-1	4.47e-04	Ccny Il12rb2 Mst1 Retreg2
Conditioned locomotion	13825.54	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Intermittent access intake day 1-15 change	52654.67	4	2	50	-1	1.38e-05	Ccny Il12rb2 Mst1 Retreg2
Intermittent access intake escalation	104773.43	2	1	25	0	1.00e+00	Mst1 Retreg2
Intermittent access intake escalation 2	27027.92	4	2	50	-1	7.84e-04	Ccny Il12rb2 Mst1 Retreg2
Intermitt. access day 1 inactive lever presses	78853.42	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Intermitt. access day 15 inactive lever presses	208241.66	1	1	25	0	1.00e+00	Retreg2
Intermitt. access escalation Index	46261.06	4	2	50	1	5.57e-05	Ccny Il12rb2 Mst1 Retreg2
Intermittent access day 1 total infusions	51844.88	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Intermittent access day 15 total infusions	43834.02	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Intermittent access terminal intake (last 3 days)	27741.87	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Intermittent access total infusions	237.98	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Intermittent access day 1 locomotion	52247.41	2	2	50	0	1.00e+00	Ccny Retreg2
Intermittent access day 15 total locomotion	88947.95	2	2	50	0	1.00e+00	Ccny Retreg2
Intermittent access total locomotion	244.05	3	1	25	0	1.00e+00	Il12rb2 Mst1 Retreg2
Intermittent access standard deviation	67321.91	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Cocaine induced anxiety	53433.95	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Post-drug Anxiety	10237.65	2	1	25	0	1.00e+00	Il12rb2 Retreg2
Baseline Anxiety	51769.43	2	2	50	0	1.00e+00	Ccny Retreg2
Lifetime Intake	2298.66	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Incentive Sensitization - Responses	81797.54	2	2	50	0	1.00e+00	Ccny Retreg2
Incentive Sensitization - Breakpoint	71404.4	2	2	50	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 active lever presses	49966.26	2	2	50	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 breakpoint	48151.76	2	2	50	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 inactive lever presses	37782.71	4	3	75	-1	2.58e-04	Ccny Il12rb2 Mst1 Retreg2
Progressive ratio test 2 active lever presses	28633.56	2	2	50	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 breakpoint	17520.06	2	2	50	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 inactive lever presses	54708.3	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Total sessions with >9 infusions	2021.84	4	3	75	0.99	1.00e-02	Ccny Il12rb2 Mst1 Retreg2
Short access day 1 total inactive lever presses	28618.41	4	4	100	1	4.25e-05	Ccny Il12rb2 Mst1 Retreg2
Short access day 10 total inactive lever presses	54316.81	4	3	75	-1	5.75e-04	Ccny Il12rb2 Mst1 Retreg2
Short access day 1 total infusions	27939.57	4	3	75	1	1.11e-03	Ccny Il12rb2 Mst1 Retreg2
Short access day 10 total infusions	25440.74	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Short access total infusions	11354.15	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Short access day 1 locomotion	42054.78	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 10 total locomotion	60537.65	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Short access total locomotion	22764.15	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Compulsive drug intake	16365.51	4	1	25	1	2.53e-04	Ccny Il12rb2 Mst1 Retreg2
One hour access (0.3 mA shock)	3244.14	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
One hour access (shock baseline)	70135.77	2	1	25	0	1.00e+00	Ccny Retreg2
Number of responses in last shaping day	17144.55	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Context. condit. distance diff. score	488.1	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 1	4877.16	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion distance, session 1	1479.21	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion velocity, session 2	4702.2	2	2	50	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 2	609.18	4	1	25	-0.99	9.55e-03	Ccny Il12rb2 Mst1 Retreg2
Locomotion velocity, session 3	2332.53	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	2943.11	2	1	25	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving duration, day 3	6074.03	2	1	25	0	1.00e+00	Mst1 Retreg2
Locomotion velocity, session 7	708.6	2	2	50	0	1.00e+00	Mst1 Retreg2
Locomotion distance, session 7	1934.91	2	2	50	0	1.00e+00	Mst1 Retreg2
Stereotopy head waving bouts, day 7	10466.92	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	8847.36	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 8	950.4	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion distance, session 8	673.32	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization distance	7696.03	2	2	50	0	1.00e+00	Mst1 Retreg2
Degree of sensitization stereotypy	4253.61	2	1	25	0	1.00e+00	Mst1 Retreg2
Condit. Reinf. active minus inactive responses	2066.34	2	1	25	0	1.00e+00	Ccny Retreg2
Condit. Reinf. active-inactive response ratio	1097.66	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	5839.15	2	1	25	0	1.00e+00	Ccny Retreg2
Condit. Reinf. inactive responses	6463.73	3	1	25	0	1.00e+00	Il12rb2 Mst1 Retreg2
Incentive salience index mean	4936.47	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Condit. Reinf. lever presses	7158.18	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Time in familiar zone, hab. session 1	20942.14	2	1	25	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 1	17770.84	2	1	25	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 1	1818.53	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	567.95	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion velocity, hab. session 1	383.06	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Time in familiar zone, hab. session 2	11707.23	2	2	50	0	1.00e+00	Mst1 Retreg2
Time in novel zone, hab. session 2	12499.19	2	2	50	0	1.00e+00	Mst1 Retreg2
Total zone transitions, hab. session 2	99.31	3	1	25	0	1.00e+00	Il12rb2 Mst1 Retreg2
Total locomotion distance, hab. session 2	36.22	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion velocity, hab. session 2	53.75	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Novel to familiar place preference ratio	18511.87	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Novelty place preference	18137	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Time in novel zone, NPP test	13621.61	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Total zone transitions, NPP test	4119.07	2	1	25	0	1.00e+00	Il12rb2 Retreg2
Total locomotion distance, NPP test	2380.74	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion velocity, NPP test	1357.92	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Pavlov. Cond. lever latency	748.85	3	2	50	0	1.00e+00	Il12rb2 Mst1 Retreg2
Pavlov. Cond. magazine entry latency	8.04	1	0	0	0	1.00e+00	Ccny
Pavlov. Cond. change in total contacts	2273.55	2	1	25	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. index score	899.58	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. latency score	935.96	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever contacts	1028.57	3	2	50	0	1.00e+00	Il12rb2 Mst1 Retreg2
Pavlov. Cond. magazine entry number	726.35	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Pavlov. Cond. intertrial magazine entries	277.69	2	2	50	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	979.4	2	1	25	0	1.00e+00	Mst1 Retreg2
Pavlov. Cond. response bias	1310.66	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: apparent density	22268.03	1	1	25	0	1.00e+00	Retreg2
Bone surface	12570.47	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone volume	16919.6	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: connectivity density	3551.77	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: cortical apparent density	22635.68	2	1	25	0	1.00e+00	Ccny Retreg2
Bone: cortical area	9496.01	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: cortical porosity	922.73	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: cortical porosity	2407.06	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: cortical thickness	845.62	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: cortical thickness	6116.53	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: cortical tissue density	24229.43	2	1	25	0	1.00e+00	Ccny Retreg2
Bone: elastic displacement	29626.25	1	1	25	0	1.00e+00	Retreg2
Bone: elastic work	757.88	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: endosteal estimation	17631.21	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: endosteal perimeter	22351.85	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: final force	3544.85	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: final moment	548.75	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: marrow area	18537.14	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: maximum diameter	12223.36	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: maximum force	17305.93	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: maximum moment	12386.14	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: minimum diameter	8606.13	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: periosteal estimation	19111.51	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: periosteal perimeter	21606.9	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: post-yield work	25428.45	2	1	25	0	1.00e+00	Mst1 Retreg2
Bone: stiffness	11873.9	3	2	50	0	1.00e+00	Il12rb2 Mst1 Retreg2
Bone: tissue strength	12264.67	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular number	41138.39	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular spacing	15656.57	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: trabecular thickness	16647.3	2	2	50	0	1.00e+00	Mst1 Retreg2
Bone: trabecular tissue density	17884.78	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Breakpoint value in progressive ratio session	37483.32	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Distance traveled before self-admin	33521.53	4	2	50	-1	1.77e-04	Ccny Il12rb2 Mst1 Retreg2
Distance traveled after self-admin	50469.31	2	2	50	0	1.00e+00	Ccny Retreg2
Delta time in closed arm before/after self-admin	519.02	4	2	50	-0.86	1.37e-01	Ccny Il12rb2 Mst1 Retreg2
Delta time in open arm before/after self-admin	18296.52	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Diff in mean of infusions in LGA sessions	54252.87	2	1	25	0	1.00e+00	Mst1 Retreg2
Extinction: sum of active levers before priming	22949.7	4	3	75	-1	2.15e-04	Ccny Il12rb2 Mst1 Retreg2
Active lever presses in extinction session 6	845.39	4	2	50	0.98	2.50e-02	Ccny Il12rb2 Mst1 Retreg2
Delta distance traveled before/after self-admin	4198.66	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Delta ambulatory time before/after self-admin	32040.15	3	3	75	0	1.00e+00	Ccny Il12rb2 Retreg2
Time in closed arm after self-admin	6616.57	3	3	75	0	1.00e+00	Ccny Mst1 Retreg2
Time in open arm before self-admin	8687	4	2	50	1	1.49e-03	Ccny Il12rb2 Mst1 Retreg2
Time in open arm after self-admin	510.42	4	3	75	-0.95	4.68e-02	Ccny Il12rb2 Mst1 Retreg2
Sum of active levers in priming session hrs 5-6	1971.15	2	2	50	0	1.00e+00	Il12rb2 Retreg2
Time to tail flick, vehicle, before self-admin	12976.19	4	3	75	-1	2.17e-03	Ccny Il12rb2 Mst1 Retreg2
Time to tail flick, vehicle, after self-admin	59159.07	2	2	50	0	1.00e+00	Ccny Retreg2
Time to tail flick, test, before self-admin	10942.43	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Time to tail flick, test, after self-admin	2994.46	2	2	50	0	1.00e+00	Ccny Retreg2
Delta time to tail flick, vehicle, before/after SA	9237.32	4	3	75	-1	3.25e-03	Ccny Il12rb2 Mst1 Retreg2
Delta time to tail flick, test, before/after SA	18951.69	3	1	25	0	1.00e+00	Ccny Mst1 Retreg2
Ambulatory time before self-admin	57050.88	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Ambulatory time after self-admin	29437.11	3	2	50	0	1.00e+00	Ccny Mst1 Retreg2
Total heroin consumption	370.93	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Area under the delay curve	40810.48	2	1	25	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 0s delay	4741.82	2	1	25	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 16s delay	37437.33	2	2	50	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 2s delay	416.46	2	1	25	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 24s delay	50025	2	2	50	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 4s delay	1298.29	2	2	50	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 8s delay	101423.99	1	1	25	0	1.00e+00	Retreg2
Delay discount exponential model param	30110.07	2	1	25	0	1.00e+00	Ccny Retreg2
Delay discount hyperbolic model param	45715.54	1	1	25	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	75084.64	2	1	25	0	1.00e+00	Ccny Retreg2
Change in fecal boli incidents, locomotor task	11821.21	2	2	50	0	1.00e+00	Ccny Retreg2
Time >=10cm from walls, locomotor time 1	16446.05	3	3	75	0	1.00e+00	Ccny Il12rb2 Retreg2
Bouts of movement, locomotor time 1	13900.93	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Total resting periods, locomotor time 1	3964.11	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Rest time, locomotor task time 1	25324.38	3	1	25	0	1.00e+00	Ccny Il12rb2 Retreg2
Distance moved, locomotor task time 1	53104.4	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Vertical activity count, locomotor time 1	109531.89	2	1	25	0	1.00e+00	Il12rb2 Retreg2
Time >=10cm from walls, locomotor time 2	54000.88	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Bouts of movement, locomotor time 2	58112.08	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Total resting periods, locomotor time 2	63369.04	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Rest time, locomotor task time 2	41900.71	2	2	50	0	1.00e+00	Ccny Retreg2
Distance moved, locomotor task time 2	17217.33	2	2	50	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 2	69238.05	2	2	50	0	1.00e+00	Ccny Retreg2
Weight adjusted by age	81026.62	2	2	50	0	1.00e+00	Ccny Retreg2
Seeking ratio, delayed vs. immediate footshock	24709.08	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber	5445.37	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Locomotion in novel chamber post-restriction	77324.49	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio	78975.01	2	2	50	0	1.00e+00	Ccny Retreg2
Food seeking constrained by brief footshock	3672.6	2	1	25	0	1.00e+00	Il12rb2 Retreg2
Seeking ratio, punishment vs. effort	39434.03	3	2	50	0	1.00e+00	Ccny Il12rb2 Retreg2
Run reversals in cocaine runway, females	18598.36	2	1	25	0	1.00e+00	Ccny Retreg2
Run reversals in cocaine runway, males	14942.17	2	1	25	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway	29317.55	2	2	50	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway, F	28379.24	1	1	25	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	3675.36	2	2	50	0	1.00e+00	Ccny Retreg2
Co content in liver	4721.74	1	1	25	0	1.00e+00	Retreg2
Cu content in liver	162.43	1	1	25	0	1.00e+00	Retreg2
Fe content in liver	5656.2	1	1	25	0	1.00e+00	Retreg2
K content in liver	6593.53	1	1	25	0	1.00e+00	Retreg2
Mg content in liver	24493.99	1	1	25	0	1.00e+00	Retreg2
Mn content in liver	4374.36	1	1	25	0	1.00e+00	Retreg2
Na content in liver	16641.94	1	1	25	0	1.00e+00	Retreg2
Rb content in liver	428.45	1	1	25	0	1.00e+00	Retreg2
Zn content in liver	15755.62	1	1	25	0	1.00e+00	Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.13
Adipose	alternative TSS	0	0	1.19
Adipose	gene expression	0	0	1.13
Adipose	isoform ratio	0	0	1.15
Adipose	intron excision ratio	0	0	0.97
Adipose	mRNA stability	0	0	1.15
BLA	alternative polyA	0	0	1.1
BLA	alternative TSS	0	0	1.15
BLA	gene expression	0	0	1.16
BLA	isoform ratio	0	0	1.18
BLA	intron excision ratio	0	0	1.15
BLA	mRNA stability	0	0	1.17
Brain	alternative polyA	0	0	1.18
Brain	alternative TSS	0	0	1.17
Brain	gene expression	0	0	1.16
Brain	isoform ratio	0	0	1.22
Brain	intron excision ratio	0	0	1.16
Brain	mRNA stability	0	0	1.18
Eye	alternative polyA	0	0	1.24
Eye	alternative TSS	0	0	1.05
Eye	gene expression	0	0	1.08
Eye	isoform ratio	0	0	1.39
Eye	intron excision ratio	0	0	1.14
Eye	mRNA stability	0	0	1.18
IC	alternative polyA	0	0	1.16
IC	alternative TSS	0	0	1.12
IC	gene expression	0	0	1.19
IC	isoform ratio	0	0	1.23
IC	intron excision ratio	0	0	1.16
IC	mRNA stability	0	0	1.19
IL	alternative polyA	0	0	1.04
IL	alternative TSS	0	0	1.14
IL	gene expression	0	0	1.16
IL	isoform ratio	0	0	1.2
IL	intron excision ratio	0	0	1.24
IL	mRNA stability	0	0	1.17
LHb	alternative polyA	0	0	1.11
LHb	alternative TSS	0	0	1.16
LHb	gene expression	0	0	1.13
LHb	isoform ratio	0	0	1.23
LHb	intron excision ratio	0	0	1.06
LHb	mRNA stability	0	0	1.16
Liver	alternative polyA	0	0	1.12
Liver	alternative TSS	0	0	1.07
Liver	gene expression	0	0	1.12
Liver	isoform ratio	1	0	1.07
Liver	intron excision ratio	0	0	1.03
Liver	mRNA stability	0	0	1.09
NAcc	alternative polyA	2	0.1	44.06
NAcc	alternative TSS	0	0	1.17
NAcc	gene expression	0	0	1.16
NAcc	isoform ratio	0	0	1.19
NAcc	intron excision ratio	0	0	1.14
NAcc	mRNA stability	0	0	1.19
OFC	alternative polyA	0	0	0.99
OFC	alternative TSS	0	0	1.03
OFC	gene expression	0	0	1.14
OFC	isoform ratio	0	0	1.15
OFC	intron excision ratio	0	0	1.03
OFC	mRNA stability	0	0	1.14
PL	alternative polyA	0	0	1.09
PL	alternative TSS	0	0	1.14
PL	gene expression	0	0	1.16
PL	isoform ratio	0	0	1.18
PL	intron excision ratio	0	0	1.14
PL	mRNA stability	0	0	1.21
pVTA	alternative polyA	0	0	1.11
pVTA	alternative TSS	0	0	1.14
pVTA	gene expression	1	0	1.19
pVTA	isoform ratio	0	0	1.21
pVTA	intron excision ratio	0	0	1.14
pVTA	mRNA stability	0	0	1.21
RMTg	alternative polyA	0	0	1
RMTg	alternative TSS	0	0	1.14
RMTg	gene expression	0	0	1.17
RMTg	isoform ratio	0	0	1.24
RMTg	intron excision ratio	0	0	1.01
RMTg	mRNA stability	0	0	1.17