Hub : Genes

Numa1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Numa1 0.16 0.1 2.6e-13 0.1 0.12 0.14 0.13 2.3e-11 3.1e-13 1.5e-14 4.1e-14
2 Eye mRNA stability Numa1 0.5 0.21 1.2e-03 0.05 0.02 0.1 0.04 6.0e-02 1.5e-01 1.3e-02 7.1e-02
3 Brain gene expression Numa1 0.14 0.08 2.6e-10 0.11 0.11 0.09 0.11 1.5e-10 1.7e-10 1.5e-08 2.1e-10
4 NAcc mRNA stability Numa1 0.11 0.06 2.7e-13 0.08 0.09 0.09 0.08 3.1e-12 4.9e-13 7.8e-13 8.9e-12
5 Brain mRNA stability Numa1 0.29 0.13 0.0e+00 0.24 0.27 0.26 0.26 3.1e-22 5.4e-25 4.1e-24 1.2e-24
6 Liver mRNA stability Numa1 0.05 0.04 2.6e-04 0.01 0.02 0.01 0.02 1.4e-02 8.9e-04 7.2e-03 2.8e-03
7 Adipose mRNA stability Numa1 0.18 0.1 1.1e-16 0.11 0.13 0.13 0.13 9.1e-12 1.2e-14 3.3e-14 3.7e-14
8 Brain isoform ratio XM_039113350.2 0.03 0.03 5.5e-03 0.02 0.01 0.01 0.01 3.0e-03 4.3e-02 4.8e-02 1.9e-02
9 OFC gene expression Numa1 0.28 0.16 4.0e-03 0 0.01 -0.01 0.03 2.5e-01 1.7e-01 5.5e-01 7.6e-02
10 OFC mRNA stability Numa1 0.21 0.14 8.5e-04 0.06 0.11 0.12 0.12 2.0e-02 1.3e-03 1.1e-03 1.1e-03
11 BLA gene expression Numa1 0.09 0.07 5.4e-03 0.02 0.04 0.04 0.03 3.0e-02 3.9e-03 3.8e-03 7.0e-03
12 Liver gene expression Numa1 0.03 0.03 2.8e-03 0.02 0.02 0.01 0.02 1.2e-03 5.2e-03 4.3e-02 6.4e-03
13 Adipose intron excision ratio chr1_165739207_165745051 0.1 0.07 8.7e-08 0.06 0.06 0.05 0.06 2.8e-07 9.2e-07 3.5e-06 5.1e-07
14 Liver alternative polyA NM_001100691.1 0.03 0.02 6.5e-03 0.02 0.01 0.02 0.02 1.9e-03 9.4e-03 5.6e-03 3.3e-03
15 Liver isoform ratio NM_001100691.1 0.03 0.03 4.4e-03 0.02 0.01 0.01 0.01 4.7e-03 2.0e-02 2.0e-02 2.0e-02
16 Liver alternative TSS XM_063262821.1 0.04 0.03 4.2e-04 0.01 0.02 0.01 0 4.0e-02 5.7e-03 4.3e-02 9.5e-02
17 BLA mRNA stability Numa1 0.16 0.1 1.5e-06 0.11 0.11 0.08 0.11 2.7e-06 1.8e-06 3.2e-05 1.9e-06
18 Adipose intron excision ratio chr1_165738751_165745051 0.13 0.08 4.3e-11 0.08 0.09 0.09 0.09 3.8e-09 2.0e-10 4.6e-10 4.5e-10
19 Brain intron excision ratio chr1_165738751_165745051 0.08 0.06 2.3e-06 0.07 0.07 0.06 0.06 2.7e-07 9.4e-07 3.7e-06 2.6e-06
20 Liver alternative TSS XM_039113343.2 0.03 0.03 2.2e-03 0 0.01 -0 0 1.0e-01 1.4e-02 5.2e-01 2.5e-01
21 pVTA mRNA stability Numa1 0.11 0.08 3.0e-06 0.05 0.07 0.07 0.06 1.4e-04 3.2e-06 2.2e-06 6.5e-06
22 IC intron excision ratio chr1_165738751_165745051 0.12 0.08 2.8e-04 0.04 0.05 0.01 0.02 8.3e-03 3.5e-03 7.2e-02 6.0e-02
23 PL gene expression Numa1 0.03 0.03 9.9e-03 0.02 0.01 0.01 0.02 2.3e-03 1.4e-02 4.9e-02 5.6e-03
24 pVTA gene expression Numa1 0.06 0.05 5.8e-04 0.05 0.05 0.04 0.05 3.5e-05 1.3e-04 4.2e-04 6.8e-05
25 Adipose alternative TSS XM_039113344.2 0.03 0.03 2.4e-03 0.01 0.01 0.01 0.01 2.4e-02 2.5e-02 1.1e-02 2.3e-02
26 NAcc gene expression Numa1 0.02 0.02 7.5e-04 0.01 0.01 0.01 0.01 2.9e-02 4.2e-03 1.8e-02 4.0e-02
27 Adipose alternative TSS XM_039113344.2 0.04 0.03 4.3e-04 0.01 0.01 0.02 0.01 4.2e-02 1.6e-02 2.4e-03 5.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density0.30.52.10.21.3-0.5-0.6-0.6-0.6-0.5-0.61.10.4-0.60.30.90.90.90.3-0.3-0.30.2-0.31.5-0.1-0.4-0.4-0.9-0.1-1.1
Area under the delay curve0.40.71.30.70.8-0.6-0.8-0.9-1.0-1.0-0.80.40.8-0.11.0-0.5-0.5-0.51.1-1.1-1.10.7-1.10.4-1.10.40.4-0.6-1.0-0.6
BMI with tail0.72.37.01.0-0.9-0.6-0.00.30.60.7-0.20.1-1.1-1.7-1.9-1.5-1.6-1.6-1.81.81.8-0.21.9-0.62.2-1.3-2.32.32.42.6
BMI without tail0.73.69.9-1.0-2.51.31.82.02.22.21.4-1.6-2.00.2-2.8-0.3-0.3-0.3-2.52.42.4-0.62.4-1.42.3-0.2-0.92.92.23.1
Body weight0.41.97.6-0.1-2.41.21.11.11.21.11.3-2.0-0.60.8-1.0-1.9-1.9-1.9-0.80.70.80.90.7-1.90.51.40.42.20.42.8
Weight adjusted by age0.20.51.7-0.8-1.30.60.90.90.90.91.2-1.0-0.50.9-0.8-0.2-0.2-0.2-0.60.50.5-0.60.5-1.10.30.70.30.40.20.7
Bone surface0.30.61.6-1.3-0.51.20.90.80.70.61.0-0.7-0.21.2-0.11.11.21.2-0.00.00.0-0.0-0.0-0.0-0.31.21.0-0.2-0.5-0.2
Bone volume0.10.31.0-0.8-0.10.80.50.40.30.30.6-0.40.10.90.20.80.80.80.2-0.2-0.20.2-0.30.2-0.41.00.8-0.3-0.5-0.3
Breakpoint value in progressive ratio session0.30.51.90.91.0-0.9-0.9-0.9-0.8-0.8-1.40.50.5-1.10.8-0.6-0.7-0.70.3-0.2-0.20.1-0.20.30.1-1.0-0.9-0.20.2-0.2
Number of licking bursts1.23.67.62.82.2-2.4-2.4-2.4-2.4-2.4-2.41.82.0-1.71.7-2.1-2.1-2.11.7-1.7-1.71.8-1.61.4-1.2-0.8-0.9-1.1-0.9-1.0
Context. condit. distance diff. score3.23.96.2-2.5-2.32.12.42.52.52.52.1-1.8-2.31.3-2.31.81.81.8-2.12.12.1-2.22.0-1.71.70.30.01.81.41.6
Locomotion velocity, session 10.80.93.60.60.8-1.1-0.6-0.4-0.2-0.2-1.01.2-0.5-1.6-0.80.50.40.4-0.70.80.8-0.80.80.81.2-1.9-1.90.41.30.2
Locomotion distance, session 11.41.73.2-1.1-0.80.61.01.11.21.30.7-0.2-1.7-0.3-1.81.51.61.6-1.71.71.7-1.71.7-0.41.7-1.2-1.01.21.71.0
Locomotion velocity, session 20.70.81.9-0.4-0.10.30.40.50.60.7-0.00.2-1.1-0.6-1.20.90.80.8-1.21.21.2-1.21.2-0.11.4-1.1-1.31.11.40.8
Locomotion distance, session 21.01.42.9-0.8-0.50.60.70.91.01.10.40.0-1.5-0.5-1.51.21.11.1-1.61.61.6-1.61.6-0.41.7-1.3-1.31.11.70.9
Locomotion velocity, session 30.70.82.9-1.4-0.31.11.01.01.01.00.6-0.3-1.00.8-0.71.71.61.6-0.80.80.7-1.00.7-0.00.60.10.20.20.4-0.1
Locomotion distance, session 31.31.56.3-1.8-0.21.21.11.11.11.10.8-0.1-1.30.5-1.12.52.52.5-1.11.11.1-1.31.10.31.0-0.3-0.20.10.8-0.3
Stereotopy head waving bouts, day 30.50.51.30.60.0-0.1-0.4-0.5-0.5-0.60.0-0.10.80.30.9-1.1-1.2-1.20.9-0.9-0.91.0-0.9-0.1-1.00.81.0-0.4-1.0-0.2
Stereotopy head waving duration, day 30.20.30.6-0.6-0.50.40.60.60.70.60.7-0.3-0.60.2-0.60.50.50.5-0.60.60.6-0.60.6-0.20.5-0.10.20.20.50.2
Locomotion velocity, session 70.40.51.50.00.5-0.2-0.1-0.00.10.1-0.50.8-0.6-0.9-1.00.90.70.7-0.70.70.7-0.80.80.50.9-1.2-1.20.51.00.3
Locomotion distance, session 70.10.20.30.50.5-0.2-0.6-0.6-0.6-0.6-0.60.40.5-0.30.3-0.2-0.3-0.30.5-0.5-0.50.3-0.40.3-0.3-0.2-0.3-0.1-0.3-0.2
Stereotopy head waving bouts, day 73.03.57.7-2.8-1.72.22.32.32.32.32.2-1.3-2.01.7-1.72.72.62.6-1.71.71.7-1.81.6-0.71.20.70.80.91.00.6
Stereotopy head waving duration, day 72.83.46.8-2.6-1.82.02.32.42.32.32.2-1.4-2.01.6-1.92.32.32.3-1.91.91.9-1.91.8-1.01.40.60.61.11.20.9
Locomotion velocity, session 81.31.63.6-1.9-1.61.51.61.61.51.51.3-1.4-1.31.2-1.11.51.71.7-1.11.11.1-1.21.0-1.00.80.50.10.90.60.6
Locomotion distance, session 83.24.67.2-2.5-2.22.12.42.52.62.62.0-1.6-2.70.9-2.62.12.02.0-2.52.52.5-2.52.5-1.72.2-0.3-0.52.02.01.8
Degree of sensitization distance1.31.46.21.2-0.4-0.2-0.6-0.7-0.7-0.8-0.3-0.71.20.31.0-2.4-2.5-2.51.2-1.2-1.21.3-1.2-1.1-1.21.00.70.3-1.20.7
Degree of sensitization stereotypy5.15.712.1-3.5-2.42.83.13.13.03.02.8-2.0-2.62.3-2.23.03.03.0-2.32.32.2-2.32.1-1.41.61.00.91.41.21.1
Conditioned locomotion0.70.81.40.80.6-0.5-0.7-0.8-0.9-0.9-0.50.21.10.31.1-1.1-1.2-1.21.2-1.2-1.21.0-1.20.2-1.20.50.5-0.6-1.2-0.6
Cocaine response after cond. corrected0.81.22.71.61.0-1.5-1.4-1.4-1.4-1.4-1.20.91.1-1.11.0-1.4-1.3-1.31.0-1.0-1.01.1-0.90.6-0.7-0.4-0.5-0.6-0.5-0.5
Cocaine response after cond. not corrected0.30.41.51.00.8-1.1-0.9-0.8-0.7-0.7-0.90.90.3-1.20.0-0.4-0.3-0.30.1-0.1-0.10.3-0.00.60.2-0.6-1.0-0.10.4-0.0
Cocaine response before conditioning2.22.65.1-1.8-0.71.11.51.61.71.81.0-0.3-2.00.1-2.12.22.22.2-2.12.12.1-2.02.0-0.22.0-0.5-0.91.21.90.9
Saline control response1.31.85.2-2.0-1.82.31.71.51.41.31.9-2.0-0.52.3-0.31.01.11.1-0.10.10.1-0.2-0.0-1.3-0.52.22.00.5-0.80.4
Bone: connectivity density0.61.02.8-0.21.1-0.4-0.2-0.10.00.1-0.61.3-0.7-1.1-0.81.71.61.6-0.80.80.8-0.90.91.31.1-1.4-1.5-0.11.2-0.4
Bone: cortical apparent density1.21.94.12.01.1-1.3-1.6-1.6-1.6-1.6-1.40.81.6-1.01.4-2.0-2.0-2.01.4-1.4-1.41.6-1.40.6-1.2-0.10.1-0.6-1.0-0.3
Bone: cortical area0.10.10.6-0.3-0.60.60.40.30.30.30.3-0.8-0.00.60.2-0.1-0.0-0.00.0-0.0-0.00.1-0.1-0.6-0.20.70.30.4-0.20.4
Bone: cortical porosity0.10.10.5-0.20.2-0.1-0.0-0.1-0.2-0.2-0.1-0.10.30.40.60.20.30.30.4-0.4-0.40.2-0.40.3-0.50.40.5-0.6-0.5-0.7
Bone: cortical porosity0.10.10.4-0.4-0.00.10.20.10.10.00.2-0.20.10.50.40.40.50.50.2-0.2-0.20.1-0.30.1-0.40.50.6-0.6-0.4-0.6
Bone: cortical thickness0.30.41.80.80.9-0.8-0.8-0.7-0.6-0.5-1.00.90.1-1.3-0.0-0.1-0.0-0.0-0.10.20.2-0.10.20.60.5-1.1-1.30.20.70.1
Bone: cortical thickness0.00.10.30.0-0.30.30.10.10.10.10.2-0.4-0.10.2-0.0-0.3-0.3-0.3-0.00.00.0-0.10.0-0.6-0.00.20.20.4-0.10.4
Bone: cortical tissue density1.21.94.02.01.1-1.3-1.6-1.6-1.6-1.7-1.40.91.6-1.01.4-1.9-2.0-2.01.4-1.4-1.41.6-1.40.7-1.1-0.10.1-0.6-1.0-0.3
Condit. Reinf. active minus inactive responses0.70.83.1-0.4-1.21.00.70.50.40.31.0-1.30.21.40.5-0.8-0.8-0.80.5-0.6-0.60.5-0.6-1.2-1.01.41.80.0-1.10.3
Condit. Reinf. active-inactive response ratio1.11.25.2-0.8-1.21.20.80.60.40.31.2-1.50.42.00.8-0.5-0.4-0.40.8-0.9-0.90.8-1.0-1.0-1.42.12.3-0.4-1.6-0.2
Condit. Reinf. active responses0.50.71.90.2-0.40.3-0.1-0.2-0.3-0.40.3-0.60.80.80.9-1.0-1.0-1.01.0-1.0-1.00.9-1.0-0.5-1.21.01.4-0.4-1.2-0.2
Condit. Reinf. inactive responses0.20.30.70.80.5-0.7-0.8-0.7-0.7-0.7-0.80.60.5-0.80.4-0.6-0.5-0.50.3-0.3-0.30.4-0.30.4-0.1-0.6-0.5-0.2-0.0-0.1
Incentive salience index mean0.40.52.3-0.1-0.70.60.30.10.0-0.00.7-0.80.40.90.7-0.8-0.9-0.90.7-0.7-0.70.7-0.8-0.7-1.01.11.5-0.3-1.1-0.1
Condit. Reinf. lever presses0.00.00.1-0.0-0.00.1-0.0-0.00.0-0.00.20.1-0.1-0.10.10.1-0.0-0.0-0.00.00.0-0.10.00.00.0-0.20.2-0.20.0-0.1
Condit. Reinf. active minus inactive responses4.26.513.3-3.6-3.63.63.53.43.23.13.5-3.4-2.23.4-1.71.81.81.8-1.71.61.6-1.61.4-2.70.62.62.31.60.21.6
Condit. Reinf. active-inactive response ratio0.81.32.6-1.6-1.41.41.51.51.41.41.3-1.1-1.11.1-1.21.21.21.2-1.01.01.0-1.01.0-0.80.70.90.50.80.50.7
Condit. Reinf. active responses5.98.519.3-4.1-4.44.44.03.83.63.54.1-4.2-2.34.2-1.71.71.61.6-1.71.61.6-1.71.4-3.50.43.12.91.9-0.11.9
Condit. Reinf. inactive responses2.53.710.5-2.6-3.03.22.62.42.22.12.8-3.0-1.33.0-0.50.70.70.7-0.70.60.6-0.80.5-2.7-0.22.02.41.1-0.61.2
Condit. Reinf. lever presses10.314.928.6-5.3-5.35.25.25.14.94.85.0-4.7-3.84.2-3.33.03.03.0-3.23.13.1-3.23.0-4.11.92.52.33.01.32.9
Condit. Reinf. lever reinforcers received6.69.220.7-4.3-4.54.54.24.03.83.64.2-4.2-2.54.2-1.92.02.02.0-1.81.71.7-1.91.5-3.50.63.12.91.90.01.9
Conditioned reinforcement - actives0.10.20.8-0.40.50.40.50.40.40.4-0.1-0.1-0.70.1-0.00.80.90.9-0.50.50.5-0.70.5-0.10.40.1-0.20.50.40.4
Conditioned reinforcement - inactives0.51.42.91.41.0-1.0-1.2-1.3-1.3-1.4-0.90.81.2-0.21.7-1.2-1.3-1.31.5-1.5-1.51.1-1.50.8-1.40.50.4-1.3-1.3-1.4
Conditioned locomotion1.11.64.5-1.00.10.70.91.01.11.20.50.2-1.6-0.2-1.02.12.12.1-1.51.51.5-1.71.50.31.5-0.9-1.01.21.50.6
Patch foraging indifference point 0 sec0.92.64.7-2.1-2.12.12.02.02.02.02.2-1.5-1.61.2-2.11.51.71.7-1.51.51.5-0.51.5-0.71.10.90.81.50.91.5
Patch foraging indifference point AUC0.10.20.8-0.4-0.70.50.60.60.50.50.9-0.7-0.20.80.1-0.4-0.4-0.4-0.10.10.10.00.0-0.4-0.10.80.9-0.3-0.2-0.1
Delay disc. indifference point, 0s delay0.60.61.6-1.1-1.21.11.01.01.00.91.2-1.1-0.81.0-0.70.60.60.6-0.60.50.5-0.40.5-0.80.30.60.50.60.10.6
Delay disc. indifference point, 16s delay0.91.32.80.71.0-0.4-0.9-1.1-1.2-1.2-0.50.31.30.11.7-0.7-0.8-0.81.6-1.6-1.61.3-1.60.5-1.61.01.0-1.3-1.6-1.3
Delay disc. indifference point, 2s delay0.30.41.5-0.7-0.80.90.60.50.40.30.6-0.9-0.21.20.10.20.30.30.3-0.3-0.3-0.2-0.4-0.9-0.61.11.20.3-0.70.2
Delay disc. indifference point, 24s delay1.32.13.41.61.4-1.2-1.7-1.8-1.8-1.8-1.40.71.6-0.71.8-1.7-1.7-1.71.8-1.8-1.81.2-1.80.4-1.60.20.2-1.2-1.4-0.9
Delay disc. indifference point, 4s delay0.70.72.4-0.8-1.31.20.90.80.70.61.0-1.6-0.31.50.2-0.3-0.3-0.30.1-0.2-0.20.1-0.2-1.4-0.61.31.40.5-0.70.6
Delay disc. indifference point, 8s delay0.20.40.80.90.8-0.7-0.7-0.8-0.8-0.8-0.80.70.7-0.40.6-0.4-0.4-0.40.7-0.7-0.70.4-0.70.5-0.60.00.1-0.2-0.6-0.3
Indifference point function ln k0.20.52.0-0.8-0.30.40.40.50.50.50.1-0.1-0.80.0-0.91.41.41.4-0.70.70.7-0.80.7-0.10.7-0.4-0.40.50.70.3
Indifference point function log k0.20.52.0-0.8-0.30.40.40.50.50.50.1-0.1-0.80.0-0.91.41.41.4-0.70.70.7-0.80.7-0.10.7-0.4-0.40.50.70.3
Patch foraging total patch changes 0 sec0.82.44.7-2.0-2.02.01.91.91.91.92.0-1.4-1.61.0-2.21.41.51.5-1.61.51.6-0.41.5-0.61.20.70.61.61.01.5
Patch foraging total patch changes 12 sec0.60.82.5-1.0-1.61.41.11.01.00.91.4-1.4-0.41.3-0.6-0.2-0.1-0.1-0.30.20.30.10.2-1.2-0.11.01.20.7-0.20.9
Patch foraging total patch changes 18 sec0.51.12.7-1.5-1.41.71.41.41.31.31.5-1.1-1.01.2-1.30.70.90.9-0.80.80.8-0.40.7-0.60.40.91.00.70.30.7
Patch foraging total patch changes 24 sec0.30.92.8-1.0-1.71.51.21.11.11.01.7-1.4-0.51.4-0.8-0.2-0.1-0.1-0.40.30.40.10.3-1.1-0.01.31.10.9-0.21.0
Patch foraging total patch changes 6 sec0.50.83.3-1.1-1.30.91.11.21.21.21.8-0.7-1.00.5-1.30.50.60.6-1.01.01.0-0.61.0-0.40.70.10.60.30.70.5
Patch foraging time to switch 0 sec1.03.97.62.52.8-2.5-2.6-2.6-2.6-2.6-2.62.22.1-1.82.0-1.3-1.3-1.31.9-1.9-1.91.2-1.81.7-1.3-1.2-1.0-1.6-1.0-1.7
Patch foraging water rate 0 sec0.83.05.8-2.3-2.42.22.32.32.22.22.4-1.8-1.81.6-2.01.31.31.3-1.61.61.6-1.21.5-1.41.10.81.01.30.81.4
Patch foraging water rate 12 sec1.14.39.7-1.7-2.01.61.82.02.22.31.5-0.9-2.7-0.0-3.11.41.41.4-2.72.72.7-2.22.7-1.32.6-1.0-1.32.42.52.3
Patch foraging water rate 18 sec1.73.86.7-2.0-2.62.22.22.32.42.42.0-1.9-2.31.1-2.30.70.80.8-2.12.12.1-1.62.1-2.21.70.20.02.51.52.5
Patch foraging water rate 24 sec0.71.12.3-0.6-0.60.60.70.81.01.00.4-0.2-1.4-0.6-1.30.90.80.8-1.51.41.5-1.01.5-0.41.5-0.9-1.01.11.51.0
Patch foraging water rate 6 sec1.11.73.6-1.0-1.01.11.01.21.31.40.6-0.5-1.6-0.2-1.90.91.01.0-1.71.71.7-1.01.7-0.71.7-0.6-0.91.91.61.8
Seeking ratio, delayed vs. immediate footshock0.91.33.61.61.9-1.7-1.6-1.6-1.5-1.4-1.71.80.8-1.50.6-0.3-0.3-0.30.6-0.6-0.60.7-0.51.7-0.1-0.7-1.4-0.70.2-1.0
Distance traveled before self-admin0.20.42.20.60.1-0.8-0.5-0.4-0.3-0.2-0.60.2-0.1-1.0-0.4-0.6-0.8-0.8-0.40.40.4-0.40.4-0.30.6-1.0-1.50.70.70.7
Distance traveled after self-admin0.61.14.1-0.00.3-0.5-0.10.10.30.4-0.30.7-1.2-1.3-1.00.80.80.8-1.21.21.2-1.51.30.31.6-1.8-2.01.01.60.5
Extensor digitorum longus weight0.10.31.30.90.4-0.7-0.5-0.5-0.5-0.5-0.60.10.5-0.50.6-1.1-1.2-1.20.3-0.3-0.30.5-0.2-0.1-0.1-0.1-0.50.1-0.10.3
Bone: elastic displacement1.11.44.31.31.9-1.7-1.5-1.3-1.2-1.1-1.52.10.4-2.0-0.00.10.10.10.1-0.1-0.10.00.01.70.5-1.8-1.7-0.70.7-0.8
Bone: elastic work1.82.47.31.62.5-2.3-1.7-1.5-1.3-1.2-2.02.70.2-2.7-0.30.40.30.3-0.20.30.3-0.30.42.31.0-2.6-2.5-0.61.3-0.8
Bone: endosteal estimation0.61.65.9-1.3-1.81.81.51.31.11.01.7-2.2-0.22.40.3-0.2-0.2-0.20.2-0.2-0.20.3-0.3-1.7-0.82.41.90.4-1.10.6
Bone: endosteal perimeter0.81.95.8-1.9-2.22.01.91.71.51.52.0-2.3-0.72.4-0.40.40.50.5-0.30.30.2-0.30.1-1.8-0.42.11.80.7-0.70.8
Epididymis fat weight0.20.83.31.50.5-1.3-1.0-1.0-0.9-0.9-1.00.60.8-1.20.1-1.8-1.5-1.50.4-0.4-0.41.1-0.30.5-0.1-0.5-0.80.30.00.6
Delta time in closed arm before/after self-admin1.71.64.31.70.7-1.1-1.3-1.3-1.3-1.3-1.00.41.6-0.51.6-2.1-2.1-2.11.3-1.3-1.21.6-1.20.4-1.10.4-0.1-0.5-0.9-0.4
Delta time in open arm before/after self-admin1.41.74.8-1.9-1.62.01.81.71.61.52.2-1.4-1.12.0-0.61.21.31.3-0.60.50.5-0.90.4-1.3-0.01.31.30.1-0.30.1
Diff in mean of infusions in LGA sessions2.44.410.61.61.9-1.4-2.1-2.3-2.4-2.5-1.31.02.5-0.43.3-1.3-1.3-1.32.7-2.7-2.72.0-2.71.4-2.50.50.8-2.9-2.3-2.9
Delay discount exponential model param0.40.51.0-0.7-0.80.60.90.91.01.00.9-0.5-0.70.3-0.90.40.40.4-1.01.01.0-0.61.0-0.40.9-0.2-0.30.40.90.5
Extinction: sum of active levers before priming0.10.10.5-0.0-0.50.40.20.10.10.1-0.0-0.6-0.10.40.5-0.5-0.4-0.40.2-0.2-0.20.1-0.2-0.5-0.30.20.70.5-0.30.4
Active lever presses in extinction session 61.61.63.4-1.2-0.80.50.81.01.11.20.90.1-1.6-0.3-1.71.81.81.8-1.61.61.6-1.71.60.21.6-1.1-0.90.91.60.5
Bone: final force1.01.63.41.10.7-0.6-0.9-1.1-1.2-1.2-0.70.01.70.31.9-1.5-1.4-1.41.6-1.6-1.61.7-1.70.3-1.71.10.9-1.0-1.6-0.8
Bone: final moment0.71.12.50.80.5-0.4-0.6-0.8-0.9-1.0-0.5-0.11.40.51.6-1.2-1.2-1.21.4-1.4-1.41.4-1.40.2-1.41.10.8-0.8-1.4-0.7
Food consumed during 24 hour testing period1.63.26.1-2.5-1.61.82.12.12.12.11.9-1.2-2.01.1-1.82.42.52.5-1.91.91.9-1.81.8-0.71.50.20.21.11.30.8
Glucose0.20.30.7-0.0-0.1-0.00.10.20.30.4-0.10.1-0.6-0.4-0.60.30.30.3-0.70.70.7-0.30.7-0.00.8-0.2-0.70.90.90.7
Heart weight0.50.93.2-1.5-1.31.11.21.21.11.11.8-1.0-0.71.2-0.61.11.11.1-0.50.40.4-0.50.4-0.40.10.71.0-0.4-0.1-0.3
Delay discount hyperbolic model param0.40.51.0-0.6-0.60.50.70.80.90.90.7-0.3-0.70.1-0.90.40.40.4-1.01.01.0-0.61.0-0.21.0-0.4-0.40.40.90.4
Intermittent access intake day 1-15 change0.52.66.5-0.40.20.40.70.91.21.20.40.5-2.1-1.0-1.81.71.61.6-2.12.12.1-2.32.1-0.12.3-1.5-1.82.52.31.9
Intermittent access intake escalation0.52.85.6-0.90.20.61.01.21.41.50.70.2-2.2-0.6-1.82.12.02.0-2.12.12.1-2.42.2-0.02.2-1.3-1.62.32.21.7
Intermittent access intake escalation 20.40.73.0-0.00.50.20.40.50.60.60.10.3-0.9-0.3-0.70.90.90.9-1.01.01.0-1.11.00.01.0-0.7-0.81.71.01.4
Intermitt. access day 1 inactive lever presses0.22.75.12.31.4-1.6-2.1-2.1-2.1-2.2-1.81.41.8-0.91.7-1.6-1.7-1.72.0-2.0-1.91.7-1.91.2-1.6-0.1-0.0-0.8-1.4-1.0
Intermitt. access day 15 inactive lever presses0.10.42.11.11.4-0.9-0.8-0.7-0.7-0.7-0.61.30.3-0.60.7-0.1-0.2-0.20.5-0.5-0.4-0.2-0.40.9-0.3-0.4-0.4-0.4-0.2-0.5
Intermitt. access escalation Index0.00.00.1-0.20.20.30.10.00.0-0.00.2-0.10.00.30.30.30.40.40.2-0.2-0.20.1-0.2-0.1-0.20.30.4-0.2-0.3-0.0
Intermittent access day 1 total infusions0.20.61.8-1.2-0.61.31.21.11.00.90.8-1.2-0.51.3-0.20.70.60.6-0.40.40.3-0.20.3-0.7-0.01.10.80.2-0.20.3
Intermittent access day 15 total infusions0.41.01.7-1.0-0.11.11.21.21.21.20.8-0.5-1.30.6-0.81.31.21.2-1.11.11.1-1.31.1-0.50.90.3-0.21.30.81.0
Intermittent access terminal intake (last 3 days)0.61.02.8-1.0-0.41.41.31.31.21.20.8-0.8-1.20.9-0.71.11.01.0-0.91.00.9-1.20.9-0.80.70.60.21.70.51.3
Intermittent access total infusions0.81.02.7-0.9-0.51.41.31.31.21.20.7-0.9-1.11.0-0.50.90.80.8-0.90.90.9-1.00.9-0.80.60.80.31.70.41.3
Intermittent access day 1 locomotion0.20.30.7-0.20.60.40.1-0.0-0.1-0.10.10.20.30.60.40.80.60.60.5-0.5-0.50.6-0.50.9-0.60.80.6-0.7-0.7-0.8
Intermittent access day 15 total locomotion0.20.93.2-0.70.70.30.40.50.50.6-0.10.5-1.0-0.5-0.91.81.81.8-1.01.01.0-1.11.00.81.1-0.7-0.90.61.10.4
Intermittent access total locomotion0.40.51.6-0.70.20.90.80.80.70.70.5-0.2-0.60.6-0.51.21.21.2-0.60.60.5-0.50.50.30.40.50.11.00.30.7
Intermittent access standard deviation0.10.52.00.4-0.3-0.00.10.20.30.40.20.0-0.9-0.6-0.4-0.5-0.5-0.5-0.80.70.8-1.10.8-0.90.9-0.5-0.91.41.01.3
Left kidney weight0.11.02.7-0.1-1.60.60.80.90.90.91.2-1.2-0.60.4-0.5-1.3-1.4-1.4-0.80.70.80.10.8-1.50.60.90.11.20.61.6
Right kidney weight0.21.44.0-0.2-2.00.91.01.01.00.91.7-1.8-0.31.1-0.1-1.7-1.8-1.8-0.40.30.40.60.3-1.9-0.01.80.91.1-0.11.6
Cocaine induced anxiety1.33.55.92.32.0-2.3-2.3-2.4-2.4-2.4-1.91.82.3-1.21.6-1.3-1.3-1.32.2-2.1-2.11.6-2.11.9-1.7-0.2-0.0-1.3-1.5-1.5
Post-drug Anxiety2.32.64.81.61.0-1.4-1.5-1.7-1.8-1.9-1.20.92.2-0.01.8-1.4-1.4-1.42.2-2.2-2.21.6-2.21.1-2.10.71.1-1.6-2.0-1.6
Baseline Anxiety0.71.23.8-1.4-1.61.71.61.51.31.31.8-1.5-0.51.90.10.20.20.2-0.30.30.30.10.2-1.1-0.31.51.8-0.4-0.5-0.1
Tail length0.94.716.1-2.4-3.33.22.62.31.91.83.1-3.7-0.34.00.3-0.3-0.3-0.30.3-0.4-0.40.9-0.6-2.5-1.53.63.70.4-1.90.8
Length with tail1.04.314.9-1.9-3.13.02.21.91.61.42.7-3.5-0.13.60.5-0.8-0.8-0.80.5-0.6-0.61.3-0.8-2.6-1.63.93.50.8-1.91.2
Length without tail0.10.32.80.0-0.40.50.1-0.0-0.1-0.10.3-0.60.30.50.7-0.5-0.5-0.50.5-0.5-0.50.9-0.5-0.5-0.71.70.70.3-0.70.4
Times rat made contact with spout0.30.40.90.6-0.1-0.0-0.5-0.6-0.6-0.7-0.4-0.20.80.00.8-0.8-0.7-0.70.8-0.8-0.81.0-0.8-0.2-0.70.60.30.0-0.70.1
Lifetime Intake1.11.42.8-1.2-0.71.71.61.61.51.50.9-1.1-1.41.1-0.71.11.11.1-1.21.21.1-1.21.1-1.00.80.80.31.70.61.4
Liver weight, left0.61.13.01.00.1-0.3-0.7-0.8-0.9-0.9-0.7-0.31.20.31.3-1.5-1.5-1.51.2-1.3-1.31.7-1.3-0.2-1.31.40.6-0.1-1.3-0.0
Liver weight, right1.01.85.91.30.0-0.5-0.6-0.8-0.9-1.0-0.5-0.51.50.61.4-2.4-2.3-2.31.5-1.5-1.52.1-1.5-0.3-1.61.71.0-0.1-1.60.3
Locomotor activity0.50.81.5-0.9-1.21.01.01.11.11.11.1-0.9-1.00.3-1.10.20.50.5-1.11.01.1-0.61.0-0.80.9-0.2-0.11.00.81.1
Locomotor testing distance0.82.04.5-1.6-2.12.01.81.81.81.81.8-1.8-1.31.2-1.20.40.60.6-1.31.31.3-0.51.3-1.60.90.80.51.60.81.7
Locomotor testing rearing0.30.92.9-0.9-1.71.51.21.11.01.01.0-1.7-0.31.3-0.3-0.3-0.1-0.1-0.30.30.30.30.3-1.5-0.01.30.91.3-0.21.4
Locomotion in novel chamber0.50.73.00.61.3-1.0-0.8-0.7-0.5-0.4-1.01.40.0-1.7-0.10.40.40.4-0.40.40.4-0.00.51.40.8-1.4-1.4-0.41.0-0.4
Locomotion in novel chamber post-restriction0.41.24.1-1.5-0.31.21.11.11.11.20.7-0.2-1.30.3-0.92.02.02.0-1.21.21.2-1.11.20.01.1-0.2-0.30.21.00.1
Fecal boli incidents, locomotor time 10.61.53.51.11.9-1.4-1.6-1.6-1.6-1.6-1.71.41.1-1.01.1-0.2-0.1-0.11.3-1.2-1.30.4-1.21.5-0.9-0.9-0.4-1.1-0.8-1.4
Change in fecal boli incidents, locomotor task0.20.20.7-0.1-0.60.40.60.60.60.60.7-0.5-0.10.5-0.2-0.4-0.4-0.4-0.40.30.40.30.3-0.50.20.80.50.50.10.7
Time >=10cm from walls, locomotor time 10.30.31.1-0.8-0.61.00.90.80.70.70.9-0.5-0.30.8-0.20.70.60.6-0.20.20.2-0.20.2-0.1-0.10.71.0-0.2-0.2-0.1
Bouts of movement, locomotor time 10.40.52.0-0.20.10.1-0.1-0.2-0.3-0.30.70.00.70.90.50.00.10.10.8-0.9-0.80.8-0.90.5-1.01.00.8-1.4-1.0-1.4
Total resting periods, locomotor time 10.30.41.50.20.6-0.4-0.4-0.5-0.5-0.50.10.70.60.20.20.20.30.30.7-0.7-0.70.4-0.70.9-0.70.40.3-1.2-0.7-1.2
Rest time, locomotor task time 10.10.20.70.30.7-0.1-0.1-0.2-0.2-0.2-0.10.70.40.30.20.30.30.30.5-0.5-0.50.2-0.50.9-0.50.50.4-0.6-0.6-0.7
Distance moved, locomotor task time 10.10.21.1-0.2-0.60.20.00.00.10.1-0.1-0.8-0.3-0.20.1-0.3-0.4-0.4-0.30.30.3-0.10.3-1.10.3-0.1-0.40.70.40.7
Vertical activity count, locomotor time 10.00.21.0-0.0-0.40.6-0.1-0.2-0.2-0.2-0.2-0.80.20.20.8-0.7-0.7-0.70.3-0.3-0.30.2-0.3-1.0-0.30.30.10.2-0.30.2
Time >=10cm from walls, locomotor time 20.61.85.9-1.3-1.92.21.81.61.41.32.1-1.8-0.42.30.20.00.00.0-0.10.00.0-0.3-0.1-1.7-0.72.32.40.3-0.90.6
Bouts of movement, locomotor time 20.51.74.70.3-0.30.50.1-0.2-0.4-0.50.4-1.01.31.71.6-1.5-1.5-1.51.5-1.5-1.61.5-1.6-0.6-1.92.21.9-0.9-2.1-0.7
Total resting periods, locomotor time 20.41.63.80.70.20.0-0.3-0.6-0.7-0.8-0.1-0.61.41.21.7-1.5-1.6-1.61.6-1.6-1.61.6-1.7-0.2-1.91.81.5-1.0-1.9-0.8
Rest time, locomotor task time 20.91.63.61.71.9-1.8-1.7-1.7-1.6-1.6-1.91.61.2-1.50.6-0.9-0.9-0.91.0-0.9-0.90.8-0.91.4-0.5-1.0-1.1-0.9-0.3-0.9
Distance moved, locomotor task time 21.51.94.3-1.5-2.11.91.81.81.71.71.8-1.7-1.31.6-0.90.60.60.6-1.01.01.0-1.30.9-2.00.51.31.01.40.31.4
Vertical activity count, locomotor time 20.20.61.9-0.2-0.80.90.50.30.20.20.5-1.10.11.40.8-0.7-0.7-0.70.5-0.5-0.5-0.2-0.5-1.4-0.81.31.30.3-0.90.4
Light reinforcement 10.41.85.31.91.9-2.2-1.8-1.6-1.4-1.3-1.92.00.7-2.30.1-0.6-0.8-0.80.2-0.2-0.20.6-0.11.70.4-1.9-1.9-0.30.7-0.3
Light reinforcement 21.02.36.60.00.6-0.90.00.30.60.7-0.51.2-1.5-1.9-1.81.21.11.1-1.92.02.0-1.62.10.82.4-2.6-2.61.02.50.7
Bone: marrow area0.61.45.3-1.1-1.61.61.31.10.90.81.5-2.0-0.02.30.4-0.4-0.3-0.30.3-0.3-0.40.4-0.5-1.5-0.92.31.80.3-1.20.5
Bone: maximum diameter1.01.95.2-1.8-2.22.01.91.81.61.62.0-2.3-0.92.2-0.50.40.50.5-0.60.50.5-0.60.4-1.9-0.11.81.50.9-0.31.0
Bone: maximum force0.30.61.40.60.6-0.4-0.6-0.7-0.8-0.8-0.50.01.10.21.2-0.7-0.6-0.61.0-1.0-1.01.1-1.00.3-1.00.80.4-0.6-1.0-0.5
Bone: maximum moment0.10.20.70.30.4-0.1-0.3-0.4-0.4-0.4-0.3-0.00.70.30.8-0.4-0.4-0.40.7-0.6-0.70.7-0.70.2-0.70.70.2-0.3-0.7-0.3
Mean time between licks in bursts0.74.012.5-1.9-3.12.72.42.11.91.72.8-3.3-0.43.50.1-0.8-0.9-0.90.1-0.2-0.20.1-0.3-2.9-1.13.23.30.9-1.51.3
Mean num. licks in bursts1.13.06.1-2.5-2.32.42.22.22.22.12.2-2.0-1.81.7-1.41.71.81.8-1.51.41.4-1.41.3-1.60.91.01.01.20.71.1
Cd content in liver0.50.51.20.40.4-0.2-0.4-0.5-0.6-0.7-0.40.11.00.50.7-0.5-0.5-0.51.0-1.0-1.00.9-1.00.4-1.10.80.7-0.5-1.1-0.5
Co content in liver1.11.34.5-1.1-1.51.71.31.10.90.81.6-1.70.02.10.2-0.3-0.4-0.40.2-0.3-0.30.3-0.4-1.4-0.82.12.00.3-1.00.5
Cu content in liver0.60.72.6-0.6-1.11.10.70.50.40.31.0-1.40.31.50.7-0.5-0.4-0.40.5-0.6-0.60.6-0.6-1.1-0.91.61.6-0.0-1.10.2
Fe content in liver0.10.10.2-0.10.30.2-0.2-0.2-0.3-0.3-0.10.20.2-0.00.50.40.50.50.3-0.3-0.30.3-0.30.3-0.30.10.2-0.5-0.3-0.5
K content in liver0.30.30.90.80.3-0.6-0.7-0.7-0.7-0.7-0.50.20.6-0.40.7-1.0-0.9-0.90.6-0.6-0.60.7-0.60.0-0.50.00.0-0.3-0.4-0.0
Mg content in liver0.20.20.5-0.1-0.2-0.00.20.20.30.30.1-0.0-0.5-0.4-0.50.20.20.2-0.60.60.6-0.50.6-0.10.7-0.5-0.40.30.70.5
Mn content in liver1.01.13.31.01.5-1.6-1.2-1.1-1.0-0.9-1.71.60.2-1.80.10.40.50.5-0.10.10.1-0.10.21.40.6-1.7-1.8-0.40.8-0.6
Na content in liver1.01.12.4-1.3-0.91.01.01.11.11.20.9-0.6-1.30.3-1.01.51.51.5-1.21.21.2-1.21.1-0.51.0-0.2-0.30.60.90.5
Rb content in liver0.20.20.8-0.5-0.20.60.20.10.0-0.00.3-0.50.20.60.40.30.50.50.4-0.4-0.40.4-0.5-0.0-0.60.90.9-0.3-0.7-0.3
Se content in liver3.44.09.62.43.1-2.4-2.7-2.7-2.6-2.5-3.02.61.8-2.41.8-0.6-0.5-0.51.6-1.5-1.51.5-1.42.5-0.8-1.5-1.6-1.7-0.5-1.8
Sr content in liver1.81.63.2-0.9-0.30.40.80.91.11.10.40.3-1.6-0.6-1.81.51.31.3-1.71.71.7-1.81.70.01.8-1.4-1.30.91.80.7
Zn content in liver1.72.03.4-1.7-1.81.81.81.81.81.81.8-1.5-1.71.1-1.40.80.60.6-1.41.41.4-1.41.4-1.61.00.40.51.30.91.4
Bone: minimum diameter0.61.24.4-0.6-1.51.10.80.60.50.41.1-1.90.41.80.7-1.0-0.8-0.80.6-0.6-0.70.7-0.7-1.5-1.12.11.60.4-1.30.6
Time in familiar zone, hab. session 10.20.20.5-0.4-0.60.50.60.50.50.50.4-0.6-0.40.5-0.50.10.10.1-0.40.40.4-0.40.4-0.70.30.3-0.00.70.20.7
Time in novel zone, hab. session 10.40.50.90.70.4-0.5-0.6-0.7-0.7-0.8-0.40.20.9-0.11.0-0.8-0.7-0.70.9-0.9-0.90.9-0.90.3-0.90.40.5-0.7-0.8-0.6
Total zone transitions, hab. session 10.60.82.7-1.0-0.20.60.60.60.70.70.30.1-1.1-0.2-0.91.61.61.6-1.01.01.0-1.01.00.21.0-0.7-0.80.30.90.1
Total locomotion distance, hab. session 10.81.14.40.8-0.70.2-0.3-0.4-0.5-0.60.1-0.80.90.60.9-2.0-2.1-2.11.0-1.1-1.11.2-1.1-1.0-1.21.11.20.2-1.20.6
Locomotion velocity, hab. session 10.60.83.80.8-0.40.1-0.3-0.4-0.4-0.5-0.0-0.50.70.30.7-1.8-1.9-1.90.8-0.9-0.81.0-0.9-0.8-0.90.70.90.2-0.90.5
Time in familiar zone, hab. session 21.61.85.2-1.4-2.31.71.81.71.51.52.0-2.2-0.72.2-0.5-0.3-0.3-0.3-0.40.40.4-0.40.3-2.1-0.21.81.71.0-0.51.2
Time in novel zone, hab. session 21.11.24.30.91.6-1.1-1.1-0.9-0.7-0.6-1.41.8-0.2-2.1-0.40.60.50.5-0.50.50.5-0.40.61.41.0-2.0-2.1-0.21.2-0.3
Total zone transitions, hab. session 22.63.35.9-2.4-1.71.82.02.12.22.21.9-1.1-2.30.8-2.02.32.32.3-2.02.02.0-2.12.0-0.91.7-0.2-0.21.01.50.8
Total locomotion distance, hab. session 20.81.13.7-0.2-1.71.20.80.70.70.61.1-1.7-0.11.30.0-1.4-1.6-1.60.1-0.1-0.10.3-0.2-1.9-0.51.31.21.0-0.61.4
Locomotion velocity, hab. session 20.81.13.5-0.1-1.61.10.70.60.50.41.0-1.60.11.20.2-1.5-1.7-1.70.2-0.3-0.30.5-0.3-1.9-0.61.41.30.8-0.71.2
Novel to familiar place preference ratio0.91.23.7-0.1-0.10.6-0.1-0.3-0.4-0.50.5-0.61.11.21.4-0.6-0.6-0.61.4-1.4-1.41.4-1.5-0.1-1.71.81.9-1.2-1.8-0.9
Novelty place preference0.81.03.3-0.1-0.20.70.0-0.2-0.3-0.40.5-0.61.01.31.2-0.6-0.6-0.61.2-1.3-1.21.2-1.3-0.2-1.61.71.8-1.0-1.6-0.8
Time in novel zone, NPP test0.81.03.8-0.3-0.40.80.20.0-0.2-0.30.7-0.80.91.41.1-0.6-0.6-0.61.2-1.2-1.21.1-1.3-0.4-1.51.82.0-0.9-1.6-0.7
Total zone transitions, NPP test1.01.53.3-0.6-0.10.00.30.60.70.80.10.5-1.4-1.1-1.51.51.51.5-1.51.51.5-1.51.60.31.8-1.7-1.60.71.80.5
Total locomotion distance, NPP test0.40.52.91.0-0.3-0.4-0.4-0.3-0.2-0.2-0.3-0.0-0.0-0.8-0.3-1.5-1.7-1.7-0.20.10.20.10.2-0.70.3-0.6-0.50.90.41.2
Locomotion velocity, NPP test0.40.62.91.30.0-0.6-0.7-0.6-0.5-0.4-0.60.30.1-1.1-0.1-1.5-1.7-1.7-0.10.10.10.20.1-0.40.3-0.9-0.80.80.51.1
Intraocular pressure0.30.51.6-0.21.0-0.5-0.1-0.00.00.1-0.21.1-0.4-0.7-0.41.11.11.1-0.50.60.6-0.60.61.30.7-0.9-0.7-0.80.8-0.9
Delta distance traveled before/after self-admin0.91.03.0-1.6-0.71.41.31.21.21.21.1-0.8-1.01.1-0.41.51.71.7-0.70.70.7-0.80.6-0.40.40.60.70.40.20.1
Delta ambulatory time before/after self-admin0.61.03.3-1.5-0.51.31.21.11.11.11.0-0.5-1.00.8-0.51.61.81.8-0.80.80.8-0.90.7-0.20.50.30.50.20.4-0.1
Parametrial fat weight0.61.35.40.81.1-1.2-0.6-0.4-0.2-0.1-1.31.4-0.7-2.0-0.80.40.40.4-1.11.21.2-0.71.31.01.7-1.9-2.30.81.80.6
Pavlov. Cond. lever latency0.40.51.31.10.7-1.1-0.9-0.8-0.7-0.6-1.00.80.4-1.1-0.1-0.7-0.7-0.70.1-0.0-0.00.20.00.50.3-0.9-1.10.10.40.1
Pavlov. Cond. magazine entry latency2.43.16.0-2.3-2.52.42.42.32.32.22.1-2.2-1.91.8-1.41.21.11.1-1.51.51.5-1.51.4-2.10.91.01.01.50.61.5
Pavlov. Cond. change in total contacts0.70.82.7-1.3-1.11.41.11.00.80.71.3-1.2-0.21.70.20.50.50.50.1-0.2-0.20.1-0.3-0.8-0.61.51.6-0.1-0.8-0.1
Pavlov. Cond. index score1.31.73.9-1.9-1.72.01.81.71.71.61.8-1.6-1.31.6-0.71.11.11.1-0.90.90.9-1.00.8-1.40.41.01.20.70.10.7
Pavlov. Cond. latency score1.11.43.4-1.8-1.51.91.71.61.51.41.6-1.5-1.01.6-0.51.01.01.0-0.70.60.6-0.80.6-1.30.21.11.30.5-0.10.5
Pavlov. Cond. lever contacts0.50.61.7-1.2-0.91.31.11.00.90.91.1-0.9-0.71.1-0.20.90.80.8-0.40.40.4-0.50.3-0.70.10.70.80.2-0.10.1
Pavlov. Cond. magazine entry number1.92.45.22.22.2-2.3-2.2-2.1-2.0-1.9-2.12.01.5-1.91.0-1.2-1.2-1.21.1-1.1-1.11.1-1.01.7-0.6-1.2-1.2-1.1-0.3-1.1
Pavlov. Cond. intertrial magazine entries0.70.81.41.10.9-0.9-1.2-1.2-1.2-1.2-0.90.71.2-0.71.1-0.7-0.5-0.51.0-1.0-1.01.0-1.00.8-0.8-0.2-0.1-0.9-0.7-0.8
Pavlov. Cond. lever-magazine prob. diff.1.11.43.3-1.8-1.41.81.71.61.51.51.6-1.4-1.11.5-0.61.21.11.1-0.80.80.8-0.90.7-1.10.30.91.10.50.10.5
Pavlov. Cond. response bias1.01.22.6-1.5-1.41.61.51.51.51.41.4-1.3-1.21.1-0.80.80.70.7-1.01.01.0-1.00.9-1.30.60.60.60.80.40.8
Pavlov. Cond. lever latency13.819.333.95.85.7-5.5-5.7-5.7-5.6-5.6-5.44.74.8-3.94.3-3.7-3.6-3.64.2-4.1-4.14.2-4.04.4-2.9-1.8-1.6-3.7-2.3-3.5
Pavlov. Cond. magazine entry latency4.96.911.7-2.5-2.52.12.72.93.03.12.1-1.5-3.30.6-3.42.11.91.9-3.33.33.3-3.33.3-2.03.0-1.0-1.02.82.82.6
Pavlov. Cond. change in total contacts7.217.630.6-5.5-5.45.25.45.45.35.35.1-4.4-4.73.6-4.23.63.63.6-4.14.04.0-4.13.8-4.12.91.41.53.52.33.4
Pavlov. Cond. index score9.514.924.2-4.8-4.84.64.94.94.94.94.4-3.8-4.43.0-4.13.23.03.0-4.03.93.9-4.03.8-3.73.00.80.83.52.53.4
Pavlov. Cond. latency score8.513.621.9-4.6-4.54.24.64.64.74.74.1-3.4-4.32.6-4.13.13.03.0-4.03.93.9-4.03.8-3.43.10.50.53.42.63.2
Pavlov. Cond. lever contacts11.717.331.2-5.5-5.65.35.45.45.35.35.2-4.6-4.43.9-4.03.33.23.2-3.93.83.8-3.83.6-4.32.61.91.83.52.03.4
Pavlov. Cond. magazine entry number7.59.714.93.63.2-3.0-3.6-3.7-3.8-3.9-3.12.23.9-1.53.8-2.9-2.7-2.73.7-3.6-3.63.8-3.62.4-3.10.40.3-2.8-2.8-2.6
Pavlov. Cond. intertrial magazine entries0.51.13.9-0.2-0.60.70.20.0-0.2-0.30.7-1.01.01.51.2-0.9-0.9-0.91.2-1.2-1.21.3-1.3-0.6-1.61.72.0-0.7-1.7-0.4
Pavlov. Cond. lever-magazine prob. diff.9.214.123.2-4.7-4.74.54.84.84.84.84.4-3.8-4.23.0-4.03.02.82.8-3.93.83.8-3.93.7-3.72.90.90.93.42.43.3
Pavlov. Cond. response bias13.919.332.2-5.7-5.65.45.65.65.65.65.2-4.5-4.93.6-4.53.73.53.5-4.44.34.3-4.44.2-4.33.21.31.33.82.63.6
Time in closed arm before self-admin1.52.74.2-2.1-1.61.81.92.02.02.01.8-1.2-2.01.0-2.01.71.71.7-1.81.81.8-1.91.7-1.41.4-0.10.51.31.31.3
Time in closed arm after self-admin0.50.50.90.70.9-1.0-0.9-0.9-0.9-0.9-0.90.50.8-0.60.9-0.8-0.8-0.80.6-0.6-0.60.8-0.60.6-0.4-0.4-0.2-0.9-0.3-0.7
Time in open arm before self-admin3.13.88.92.72.5-2.9-2.7-2.6-2.5-2.4-3.02.61.6-2.60.9-1.3-1.4-1.41.3-1.2-1.21.2-1.12.3-0.5-1.7-1.9-1.1-0.1-1.1
Time in open arm after self-admin0.00.00.2-0.0-0.30.30.20.20.10.10.4-0.0-0.10.5-0.20.10.00.00.1-0.2-0.1-0.1-0.2-0.1-0.30.40.4-0.0-0.3-0.1
Bone: periosteal estimation0.30.82.8-1.0-1.31.41.11.00.80.81.1-1.7-0.21.70.1-0.10.10.1-0.0-0.0-0.00.1-0.1-1.3-0.41.71.10.6-0.60.6
Bone: periosteal perimeter0.51.12.7-1.4-1.61.51.41.31.21.21.4-1.6-0.81.5-0.50.50.60.6-0.60.50.5-0.50.5-1.40.21.20.80.8-0.00.8
Bone: post-yield work0.10.20.6-0.3-0.70.50.50.40.40.40.3-0.7-0.20.5-0.1-0.1-0.0-0.0-0.20.20.2-0.10.2-0.70.10.50.20.6-0.00.6
Progressive ratio test 1 active lever presses0.10.10.6-0.20.60.10.10.10.00.0-0.10.2-0.10.10.30.80.60.6-0.00.10.0-0.20.00.50.00.2-0.1-0.20.0-0.4
Progressive ratio test 1 breakpoint0.10.10.6-0.20.60.10.10.10.00.0-0.20.2-0.00.10.30.80.70.7-0.00.00.0-0.2-0.00.6-0.00.3-0.0-0.2-0.0-0.4
Progressive ratio test 1 inactive lever presses0.20.41.50.91.2-0.6-0.7-0.7-0.7-0.7-0.90.90.6-0.40.70.10.00.00.6-0.6-0.60.6-0.61.0-0.40.2-0.30.0-0.4-0.2
Progressive ratio test 2 active lever presses0.10.10.5-0.50.10.60.50.40.30.30.1-0.4-0.30.60.30.50.50.5-0.10.10.1-0.10.1-0.1-0.00.70.30.2-0.10.1
Progressive ratio test 2 breakpoint0.10.10.5-0.50.10.70.50.50.40.40.2-0.4-0.30.60.20.60.50.5-0.20.20.2-0.10.1-0.10.00.70.30.3-0.10.2
Progressive ratio test 2 inactive lever presses0.00.10.30.10.50.10.20.20.20.2-0.20.3-0.4-0.10.20.40.40.4-0.40.40.4-0.60.40.00.4-0.2-0.40.50.40.4
Incentive Sensitization - Responses0.10.20.7-0.6-0.40.80.70.60.60.50.3-0.8-0.40.80.10.30.30.3-0.20.30.2-0.00.2-0.60.10.80.40.6-0.00.6
Incentive Sensitization - Breakpoint0.10.20.6-0.6-0.30.70.60.60.60.60.2-0.7-0.50.5-0.00.40.40.4-0.40.40.4-0.20.4-0.60.30.50.10.70.20.7
Sum of active levers in priming session hrs 5-60.30.30.9-0.2-0.60.30.40.50.50.50.1-0.3-0.7-0.0-0.50.10.10.1-0.60.60.6-0.90.6-0.60.6-0.4-0.20.90.60.6
Progressive ratio0.51.53.9-1.1-0.50.50.70.91.11.10.90.1-1.5-0.6-2.01.41.51.5-1.61.61.6-1.61.6-0.21.7-1.2-1.20.81.70.6
Food seeking constrained by brief footshock1.31.63.7-1.6-1.91.81.71.71.61.61.9-1.5-1.11.5-0.90.70.60.6-0.90.90.9-1.10.8-1.80.40.81.10.70.21.0
Seeking ratio, punishment vs. effort0.40.92.9-0.2-1.31.00.90.70.50.50.6-1.50.21.60.6-0.8-0.9-0.90.4-0.4-0.40.4-0.5-1.6-0.81.61.70.6-1.01.0
Retroperitoneal fat weight0.73.110.32.90.8-1.6-1.9-1.9-1.8-1.8-2.10.51.7-1.51.3-3.2-3.2-3.21.3-1.3-1.22.5-1.20.2-0.80.3-0.70.6-0.60.9
Reaction time number correct0.00.20.5-0.10.20.20.10.10.20.2-0.10.3-0.6-0.4-0.50.70.30.3-0.50.50.5-0.50.50.30.6-0.7-0.40.20.60.1
Reaction time mean minus median0.10.41.5-0.5-1.20.70.70.70.60.51.0-1.1-0.20.9-0.1-0.3-0.4-0.4-0.10.00.00.10.0-1.0-0.21.00.70.4-0.30.4
Reaction time mean minus median AUC0.00.31.1-0.6-1.00.80.70.70.60.60.9-1.0-0.40.8-0.20.1-0.1-0.1-0.20.20.2-0.10.2-0.9-0.00.80.50.6-0.10.6
Reaction time num false alarms2.13.56.92.41.8-1.8-2.1-2.2-2.2-2.2-1.91.22.5-0.91.9-2.1-2.1-2.12.1-2.1-2.12.6-2.11.3-1.80.50.3-1.0-1.6-0.8
Reaction time num false alarms AUC1.32.95.42.21.9-1.8-2.0-2.0-2.1-2.1-1.91.32.3-0.91.6-1.8-1.8-1.81.9-1.9-1.92.3-1.81.4-1.50.20.0-1.0-1.4-0.8
Reaction time trials correct on left0.00.20.5-0.10.20.20.10.10.20.2-0.10.3-0.6-0.4-0.50.70.30.3-0.50.50.5-0.50.50.30.6-0.7-0.40.20.60.1
Reaction time trials on left0.10.20.5-0.00.20.10.00.10.20.2-0.20.4-0.6-0.5-0.50.70.30.3-0.50.50.5-0.50.60.30.7-0.7-0.50.20.70.1
Reaction time mean1.33.05.62.01.0-1.3-1.6-1.8-1.9-1.9-1.40.32.1-0.22.3-2.4-2.4-2.42.2-2.1-2.11.7-2.1-0.1-2.00.60.6-1.0-1.9-0.8
Reaction time mean AUC1.33.15.82.11.3-1.4-1.8-1.9-2.0-2.1-1.60.62.2-0.32.4-2.3-2.2-2.22.2-2.2-2.21.7-2.20.1-2.00.40.5-1.1-1.9-1.0
Median of all reaction times2.54.07.02.51.6-1.8-2.1-2.3-2.4-2.4-2.00.82.4-0.62.6-2.5-2.5-2.52.4-2.4-2.41.9-2.40.3-2.10.20.3-1.2-2.0-1.1
Reaction time omissions0.30.51.51.10.5-0.5-0.7-0.7-0.7-0.7-0.70.30.6-0.60.6-1.2-1.2-1.20.5-0.5-0.50.9-0.50.0-0.40.5-0.20.5-0.30.5
Reaction time false alarm rate2.02.85.12.21.7-1.8-1.9-2.0-2.0-2.0-1.81.12.2-0.91.6-2.0-1.9-1.91.9-1.8-1.82.3-1.81.2-1.50.3-0.0-0.9-1.3-0.6
Reaction time premature initiation rate0.91.43.9-1.5-1.91.71.61.51.41.31.8-2.0-0.81.8-0.10.10.10.1-0.40.40.4-0.60.3-1.9-0.11.21.40.6-0.30.8
Reaction time premature initiations0.30.92.1-1.3-1.41.51.31.31.21.21.4-1.4-1.01.2-0.40.50.40.4-0.70.70.7-0.80.6-1.30.30.50.80.60.20.6
Std. dev. reaction times0.41.32.90.5-0.50.1-0.2-0.4-0.6-0.60.1-0.91.21.11.4-1.6-1.6-1.61.4-1.4-1.41.3-1.5-1.0-1.61.61.4-0.3-1.7-0.1
Reaction time trials completed0.10.20.5-0.00.20.10.00.10.20.2-0.20.4-0.6-0.5-0.50.70.30.3-0.50.50.5-0.50.60.30.7-0.7-0.50.20.70.1
Reaction time trials AUC0.00.10.30.00.10.20.10.10.20.2-0.10.2-0.5-0.4-0.40.40.00.0-0.40.40.4-0.30.40.20.5-0.5-0.30.20.50.1
Run reversals in cocaine runway, females0.50.61.9-0.0-1.40.50.60.60.60.50.9-1.2-0.00.8-0.1-1.2-1.2-1.2-0.20.10.20.50.1-1.3-0.10.70.71.0-0.11.3
Run reversals in cocaine runway, males0.40.41.00.51.0-0.7-0.9-0.9-0.9-0.8-0.50.70.5-0.50.8-0.1-0.1-0.10.6-0.6-0.60.4-0.60.8-0.5-0.2-0.3-0.9-0.4-0.9
Latency to leave start box in cocaine runway1.01.42.51.41.2-1.2-1.4-1.5-1.6-1.6-1.50.91.2-0.61.3-0.9-0.9-0.91.5-1.4-1.50.7-1.41.1-1.2-0.30.1-0.5-1.1-1.0
Latency to leave start box in cocaine runway, F1.62.03.91.30.7-1.0-1.3-1.5-1.6-1.7-1.20.31.60.01.7-1.5-1.5-1.52.0-1.9-2.01.2-2.00.5-1.90.61.0-0.6-1.8-0.9
Latency to leave start box in cocaine runway, M0.50.52.20.51.0-0.8-0.7-0.6-0.5-0.4-0.91.1-0.2-1.2-0.10.50.50.5-0.20.30.2-0.50.31.10.6-1.5-1.2-0.20.7-0.5
Std. dev. time between licks in bursts0.81.64.5-0.4-1.71.00.90.70.50.41.2-1.90.42.10.7-1.5-1.6-1.60.7-0.7-0.70.6-0.8-1.8-1.22.02.10.2-1.40.5
Total sessions with >9 infusions1.51.93.7-1.7-1.21.91.91.81.81.71.2-1.7-1.41.4-1.21.11.11.1-1.21.31.2-1.11.1-1.40.80.90.51.80.61.7
Short access day 1 total inactive lever presses0.20.41.10.60.7-0.1-0.4-0.5-0.6-0.6-0.30.40.60.40.8-0.6-0.4-0.41.0-1.0-1.00.3-1.00.3-1.00.60.7-0.7-1.1-0.6
Short access day 10 total inactive lever presses0.32.05.32.32.1-1.5-1.7-1.8-1.8-1.8-1.51.61.7-0.91.3-1.1-1.2-1.21.5-1.5-1.51.1-1.51.3-1.2-0.2-0.0-0.3-1.0-0.3
Short access day 1 total infusions1.02.05.1-1.7-1.52.22.01.91.71.71.7-2.2-1.12.1-0.40.30.30.3-0.70.70.6-0.80.5-2.20.11.61.51.2-0.21.5
Short access day 10 total infusions1.01.63.9-1.4-0.91.81.71.61.61.51.0-1.4-1.31.2-1.01.31.11.1-1.11.21.1-1.01.1-1.10.80.90.42.00.61.7
Short access total infusions1.31.84.1-1.8-1.12.01.91.81.81.71.4-1.6-1.41.5-0.71.31.21.2-1.11.11.1-1.21.0-1.30.71.10.71.20.41.1
Short access day 1 locomotion0.50.92.6-1.6-0.50.81.01.01.01.00.8-0.7-1.10.3-0.81.51.51.5-1.01.01.0-0.81.0-0.20.90.2-0.20.10.80.0
Short access day 10 total locomotion0.20.92.8-0.8-0.31.10.90.91.01.00.7-0.8-1.00.2-0.81.00.90.9-1.01.01.0-1.11.0-0.80.90.0-0.21.70.81.5
Short access total locomotion0.30.41.7-0.70.10.40.40.50.50.50.00.0-0.7-0.2-0.51.31.31.3-0.70.70.7-0.70.70.40.7-0.2-0.50.70.70.2
One hour access (0.3 mA shock)0.60.71.4-0.7-0.10.80.80.90.90.90.6-0.3-1.00.2-0.50.91.01.0-1.01.01.0-1.01.0-0.40.90.1-0.41.20.80.9
Compulsive drug intake0.71.03.80.81.9-1.6-1.3-1.1-0.9-0.9-0.81.70.4-1.70.10.00.20.20.0-0.00.00.10.11.40.4-1.3-1.4-1.40.7-1.0
One hour access (shock baseline)0.71.94.3-1.4-1.61.71.71.71.71.71.0-1.2-1.80.9-1.01.21.21.2-1.51.51.5-1.61.4-1.21.20.2-0.02.11.01.4
Social response proportion0.50.63.31.20.2-0.6-0.8-0.7-0.7-0.7-0.30.40.6-0.70.4-1.7-1.8-1.80.5-0.5-0.41.0-0.40.2-0.3-0.6-0.1-0.6-0.2-0.2
Social responses1.21.67.41.40.0-0.2-0.7-0.8-0.8-0.9-0.4-0.21.20.11.1-2.7-2.7-2.71.1-1.2-1.12.2-1.10.2-1.10.90.8-0.7-1.1-0.1
Social time1.21.84.61.82.1-1.6-1.7-1.7-1.6-1.6-2.11.81.2-1.61.2-1.1-1.0-1.00.9-0.8-0.90.9-0.81.7-0.4-1.0-1.1-1.1-0.2-1.2
Soleus weight0.51.66.31.40.3-0.5-0.8-0.9-1.0-1.0-0.4-0.11.40.11.4-2.2-2.5-2.51.4-1.4-1.41.6-1.4-0.0-1.40.80.9-0.5-1.3-0.1
Bone: stiffness1.52.85.51.40.8-0.8-1.2-1.4-1.6-1.7-0.80.02.10.42.3-1.9-1.8-1.82.2-2.2-2.22.2-2.30.4-2.31.41.4-1.4-2.3-1.2
Tibialis anterior weight0.10.41.30.2-0.70.30.10.0-0.0-0.10.3-0.90.60.70.6-1.1-1.1-1.10.5-0.6-0.60.8-0.6-0.8-0.71.10.70.3-0.80.4
Time to tail flick, vehicle, before self-admin1.01.23.6-1.1-0.81.11.01.11.21.20.9-0.2-1.30.2-1.91.31.21.2-1.31.31.3-1.31.3-0.71.2-0.1-0.20.81.11.0
Time to tail flick, vehicle, after self-admin0.20.51.7-1.1-0.51.01.00.90.70.70.5-0.6-0.71.3-0.50.90.90.9-0.10.10.1-0.80.0-0.5-0.20.81.0-0.1-0.4-0.2
Time to tail flick, test, before self-admin1.31.55.6-1.7-1.72.01.71.61.41.32.4-1.4-0.52.1-0.70.80.80.8-0.30.30.3-0.10.2-1.0-0.31.71.80.1-0.50.3
Time to tail flick, test, after self-admin1.11.24.2-0.7-1.41.20.90.70.50.41.7-1.50.21.91.0-0.7-0.8-0.80.6-0.7-0.70.3-0.8-1.4-1.21.82.1-0.5-1.4-0.4
Delta time to tail flick, vehicle, before/after SA0.30.31.0-0.00.5-0.2-0.2-0.3-0.4-0.4-0.3-0.10.40.40.9-0.1-0.0-0.00.8-0.7-0.80.3-0.80.3-0.80.40.5-0.8-0.9-1.0
Delta time to tail flick, test, before/after SA0.60.71.71.30.9-1.3-1.1-1.1-1.0-1.0-1.10.70.5-1.11.0-1.2-1.3-1.30.5-0.5-0.50.3-0.50.2-0.2-0.7-0.7-0.4-0.1-0.4
Tibia length0.30.92.2-1.5-1.31.21.21.21.11.11.2-1.1-0.81.2-0.51.11.31.3-0.60.60.6-0.70.6-0.80.30.70.70.40.10.2
Ambulatory time before self-admin0.10.41.80.70.5-1.0-0.6-0.5-0.4-0.4-1.00.40.0-1.0-0.1-0.5-0.7-0.7-0.20.20.2-0.10.30.20.5-0.9-1.40.30.60.3
Ambulatory time after self-admin0.61.02.2-0.8-0.10.20.60.70.80.80.00.0-1.4-0.5-0.71.41.31.3-1.31.31.3-1.51.30.11.4-1.1-1.30.81.40.3
Bone: tissue strength1.11.24.40.51.2-1.1-0.6-0.4-0.2-0.1-0.91.6-0.6-1.7-0.90.90.80.8-1.01.01.0-0.91.11.31.4-2.0-2.10.11.6-0.1
Total heroin consumption0.30.41.1-0.2-0.80.50.50.60.70.70.2-0.5-0.7-0.1-0.4-0.1-0.1-0.1-0.80.80.8-0.50.8-0.90.8-0.3-0.41.10.81.0
Bone: trabecular number0.61.14.40.92.1-1.2-1.2-1.1-1.1-1.0-1.52.00.4-1.50.10.80.70.70.2-0.2-0.20.1-0.11.90.3-1.3-1.4-0.70.4-1.0
Bone: trabecular spacing0.91.32.4-1.1-1.00.60.91.11.21.20.8-0.4-1.6-0.3-1.41.21.31.3-1.51.51.5-1.51.5-0.51.5-1.0-0.40.91.40.8
Bone: trabecular thickness1.01.43.40.60.5-0.0-0.5-0.7-0.9-1.0-0.3-0.21.50.91.6-1.1-1.1-1.11.6-1.6-1.61.7-1.70.3-1.81.61.3-1.0-1.8-0.9
Bone: trabecular tissue density3.05.310.02.00.7-1.0-1.6-1.9-2.1-2.2-1.0-0.22.90.63.0-3.1-3.0-3.03.0-3.0-3.03.2-3.00.2-3.12.01.8-1.5-3.0-1.1
Water consumed over 24 hours0.10.20.40.60.3-0.5-0.6-0.6-0.6-0.6-0.60.30.5-0.50.4-0.4-0.2-0.20.4-0.4-0.40.5-0.30.3-0.2-0.2-0.3-0.2-0.1-0.2
Number of responses in last shaping day1.92.45.51.61.4-1.0-1.1-1.3-1.4-1.5-0.80.52.30.32.3-1.6-1.7-1.71.9-1.9-1.92.0-2.00.9-2.01.21.1-1.1-1.9-1.1