Hub : Genes

Arrb1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS XM_006229741.4 0.1 0.1 5.2e-04 0.03 0.02 0.03 0.03 2.7e-04 1.1e-03 2.1e-04 4.3e-04
2 Adipose alternative TSS XM_006229741.4 0.15 0.13 8.6e-04 0.03 0.02 0.03 0.03 2.8e-04 3.5e-03 2.2e-04 3.9e-04
3 Adipose isoform ratio XM_006229741.4 0.06 0.08 4.2e-03 0.02 0.01 0.02 0.02 3.7e-03 1.5e-02 2.2e-03 2.4e-03
4 Adipose isoform ratio XM_039101685.1 0.21 0.1 0.0e+00 0.13 0.14 0.15 0.14 1.8e-14 1.7e-15 1.6e-16 3.9e-15
5 Adipose mRNA stability Arrb1 0.06 0.04 6.8e-07 0.02 0.04 0.04 0.03 1.9e-03 1.3e-05 3.8e-05 9.6e-05
6 Adipose alternative polyA XM_039101685.1 0.2 0.1 5.6e-17 0.12 0.13 0.13 0.13 6.6e-13 1.3e-14 1.7e-14 5.4e-14
7 pVTA gene expression Arrb1 0.13 0.08 1.2e-04 0.09 0.07 0.06 0.08 8.6e-05 6.5e-04 1.9e-03 3.0e-04
8 LHb gene expression Arrb1 0.3 0.14 6.2e-05 0.17 0.17 0.14 0.17 8.3e-05 6.7e-05 3.4e-04 8.9e-05
9 PL gene expression Arrb1 0.13 0.06 5.0e-16 0.13 0.14 0.13 0.14 1.5e-14 3.8e-15 2.0e-14 3.5e-15
10 BLA mRNA stability Arrb1 0.06 0.04 7.8e-03 0.03 0.03 0.01 0.02 1.7e-02 9.6e-03 1.2e-01 4.3e-02
11 Adipose gene expression Arrb1 0.34 0.13 0.0e+00 0.18 0.19 0.18 0.18 2.1e-19 1.6e-20 1.1e-19 4.0e-19
12 Brain gene expression Arrb1 0.25 0.11 0.0e+00 0.21 0.22 0.22 0.23 1.2e-19 1.1e-20 1.5e-20 9.3e-21
13 RMTg gene expression Arrb1 0.38 0.18 4.3e-06 0.15 0.17 0.18 0.18 8.4e-05 3.3e-05 1.2e-05 1.6e-05
14 IL gene expression Arrb1 0.44 0.16 1.1e-07 0.21 0.25 0.22 0.21 7.2e-06 1.1e-06 5.9e-06 7.1e-06
15 BLA gene expression Arrb1 0.37 0.14 1.8e-14 0.21 0.24 0.22 0.22 1.4e-11 3.8e-13 4.2e-12 3.0e-12
16 Brain mRNA stability Arrb1 0.13 0.07 8.7e-09 0.06 0.1 0.11 0.11 1.3e-06 1.2e-09 3.1e-10 4.5e-10
17 PL alternative polyA XM_006229740.4 0.04 0.03 1.5e-03 0 0.02 0.01 0.01 1.3e-01 5.1e-03 9.8e-03 2.3e-02
18 NAcc gene expression Arrb1 0.13 0.07 7.5e-13 0.1 0.11 0.11 0.11 1.0e-11 7.7e-13 9.4e-13 2.4e-12
19 BLA alternative polyA XM_006229740.4 0.07 0.05 3.5e-03 0.03 0.03 0.03 0.02 1.2e-02 6.6e-03 1.7e-02 2.3e-02
20 OFC gene expression Arrb1 0.35 0.17 2.6e-06 0.13 0.21 0.21 0.2 5.2e-04 1.0e-05 8.4e-06 1.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.10.20.8-0.1-0.1-0.10.80.2-0.4-0.90.30.3-0.20.40.7-0.90.20.80.40.00.6-0.10.6
Area under the delay curve0.10.10.40.0-0.0-0.0-0.2-0.2-0.10.5-0.3-0.20.3-0.2-0.50.6-0.3-0.5-0.40.2-0.40.3-0.1
BMI with tail0.10.40.70.0-0.0-0.00.5-0.3-0.60.8-0.8-0.50.6-0.4-0.60.8-0.6-0.8-0.80.7-0.70.70.6
BMI without tail2.96.09.0-1.1-1.4-1.41.1-2.3-2.12.6-2.3-2.82.9-2.7-2.62.6-2.9-2.7-2.52.6-2.82.93.0
Body weight1.76.910.3-0.8-1.2-1.21.0-2.2-2.23.1-2.7-2.93.0-2.8-3.23.2-3.0-3.2-2.92.8-3.13.02.8
Weight adjusted by age1.31.52.4-0.9-1.1-1.1-0.0-1.5-0.61.3-0.9-1.51.5-1.5-1.41.1-1.5-1.4-0.81.1-1.41.41.3
Bone surface0.61.03.8-1.9-1.9-1.9-0.4-1.50.10.50.3-0.91.0-0.7-0.4-0.1-0.9-0.10.20.3-0.30.71.2
Bone volume0.30.61.9-1.4-1.4-1.40.0-1.2-0.20.30.2-0.80.8-0.7-0.3-0.2-0.7-0.00.10.3-0.20.61.2
Breakpoint value in progressive ratio session0.30.30.70.60.60.60.20.70.2-0.80.30.7-0.60.60.4-0.50.60.50.1-0.40.5-0.6-0.5
Number of licking bursts1.61.86.52.32.12.02.51.6-2.10.1-1.80.1-0.00.5-0.20.9-0.1-0.6-1.51.4-0.60.60.5
Context. condit. distance diff. score1.41.75.2-2.3-2.0-2.0-2.1-0.91.8-0.31.70.2-0.30.50.7-0.90.50.91.3-1.40.9-0.8-0.8
Locomotion velocity, session 11.21.32.01.11.21.2-0.31.20.8-1.20.91.3-1.40.91.2-1.11.31.11.0-1.11.1-1.3-1.2
Locomotion distance, session 10.81.02.8-0.3-0.2-0.2-1.60.11.7-0.51.30.8-1.00.40.8-0.91.00.81.2-1.40.9-1.2-1.4
Locomotion velocity, session 20.00.10.30.40.40.4-0.2-0.10.10.2-0.1-0.1-0.0-0.5-0.20.2-0.1-0.2-0.1-0.0-0.20.0-0.0
Locomotion distance, session 20.20.20.9-0.1-0.1-0.1-1.0-0.20.9-0.20.70.3-0.4-0.20.3-0.40.40.40.6-0.70.4-0.5-0.5
Locomotion velocity, session 30.91.12.3-0.5-0.4-0.4-1.40.21.5-0.81.40.9-1.00.71.0-1.21.01.01.3-1.41.1-1.2-1.2
Locomotion distance, session 31.61.73.7-0.7-0.5-0.5-1.80.11.9-0.91.81.0-1.20.81.2-1.41.21.31.7-1.81.4-1.5-1.5
Stereotopy head waving bouts, day 30.50.61.10.60.40.40.9-0.1-1.00.6-1.1-0.60.7-0.7-0.80.9-0.7-0.9-1.01.0-0.90.80.8
Stereotopy head waving duration, day 30.10.10.3-0.5-0.5-0.5-0.4-0.20.4-0.30.50.2-0.10.20.3-0.40.20.40.5-0.40.4-0.2-0.1
Locomotion velocity, session 70.30.30.70.30.40.40.00.70.2-0.60.30.6-0.60.90.6-0.60.70.50.3-0.40.6-0.6-0.7
Locomotion distance, session 70.00.00.10.10.00.00.20.2-0.20.0-0.20.00.10.2-0.10.1-0.0-0.1-0.20.2-0.10.10.0
Stereotopy head waving bouts, day 70.70.83.0-1.2-1.1-1.1-1.7-0.71.6-0.11.30.2-0.3-0.20.4-0.70.40.61.1-1.20.6-0.7-0.7
Stereotopy head waving duration, day 70.70.93.1-1.6-1.5-1.5-1.7-1.31.40.31.1-0.30.2-0.70.0-0.4-0.10.20.9-0.80.2-0.2-0.2
Locomotion velocity, session 80.40.52.4-1.5-1.4-1.4-1.0-0.90.70.00.8-0.20.3-0.10.1-0.4-0.20.30.6-0.40.3-0.00.2
Locomotion distance, session 80.81.25.1-1.7-1.5-1.5-2.2-0.91.90.11.50.2-0.3-0.10.4-0.60.40.51.1-1.30.6-0.7-0.9
Degree of sensitization distance3.03.04.80.1-0.1-0.21.6-0.9-2.11.7-2.1-1.71.9-1.4-1.92.0-1.9-2.0-2.22.2-2.02.12.0
Degree of sensitization stereotypy1.61.87.0-1.8-1.7-1.6-2.6-1.22.3-0.01.80.2-0.4-0.40.5-0.90.50.71.5-1.70.8-0.9-1.0
Conditioned locomotion0.30.30.50.00.10.1-0.20.50.4-0.70.60.6-0.60.70.7-0.70.60.70.7-0.60.7-0.6-0.6
Cocaine response after cond. corrected1.01.12.61.61.41.41.40.8-1.40.6-1.5-0.20.3-0.1-0.71.1-0.4-1.0-1.51.2-0.90.70.3
Cocaine response after cond. not corrected0.30.31.21.11.01.00.60.7-0.60.3-0.80.1-0.10.1-0.30.60.0-0.4-0.80.4-0.40.1-0.2
Cocaine response before conditioning0.91.12.5-1.1-0.9-0.9-1.5-0.31.5-0.61.60.6-0.70.30.9-1.20.81.11.5-1.41.1-1.0-0.7
Saline control response1.01.23.0-1.4-1.5-1.5-1.0-1.70.31.4-0.2-1.31.2-1.5-1.10.8-1.1-1.0-0.40.4-1.00.90.9
Bone: connectivity density0.30.51.6-0.8-0.7-0.70.1-0.00.3-1.10.90.4-0.30.70.9-1.30.41.11.0-0.50.9-0.40.2
Bone: cortical apparent density0.91.13.21.31.11.11.80.5-1.80.4-1.5-0.50.6-0.3-0.70.9-0.7-0.7-1.41.4-0.80.91.1
Bone: cortical area0.60.91.8-1.3-1.3-1.3-0.1-1.3-0.41.0-0.4-1.11.1-0.8-0.90.7-1.0-0.7-0.50.7-0.81.01.2
Bone: cortical porosity1.01.12.9-0.8-0.7-0.7-1.7-0.11.6-0.61.40.8-0.80.60.8-1.00.90.91.2-1.41.0-1.1-1.2
Bone: cortical porosity0.91.02.4-0.5-0.4-0.4-1.50.11.5-0.61.40.9-0.90.60.9-1.01.01.01.2-1.41.0-1.1-1.3
Bone: cortical thickness0.00.10.20.30.30.30.50.4-0.3-0.3-0.00.3-0.20.40.3-0.20.20.30.00.10.2-0.10.1
Bone: cortical thickness0.20.30.6-0.2-0.2-0.1-0.70.10.8-0.30.70.5-0.50.40.4-0.60.60.50.5-0.70.5-0.6-0.6
Bone: cortical tissue density0.81.13.11.41.21.21.80.5-1.70.3-1.4-0.40.5-0.3-0.60.9-0.6-0.7-1.31.3-0.80.81.0
Condit. Reinf. active minus inactive responses0.70.81.3-0.5-0.7-0.70.2-1.0-0.61.0-0.7-1.11.0-1.1-0.90.8-1.1-0.9-0.70.8-0.91.01.1
Condit. Reinf. active-inactive response ratio1.41.52.5-1.2-1.3-1.30.2-1.5-0.71.3-0.7-1.51.5-1.3-1.21.0-1.5-1.1-0.91.1-1.21.41.6
Condit. Reinf. active responses0.20.20.50.0-0.1-0.10.2-0.4-0.40.5-0.5-0.50.5-0.7-0.50.5-0.5-0.5-0.40.5-0.50.50.6
Condit. Reinf. inactive responses0.20.20.50.70.70.7-0.10.50.3-0.30.20.5-0.60.20.3-0.30.50.30.3-0.40.3-0.5-0.6
Incentive salience index mean0.40.51.2-0.5-0.6-0.6-0.0-0.9-0.30.9-0.5-0.90.9-1.1-0.80.7-0.9-0.7-0.50.6-0.80.80.9
Condit. Reinf. lever presses0.10.10.4-0.2-0.2-0.2-0.3-0.50.10.4-0.0-0.30.3-0.6-0.30.2-0.3-0.2-0.00.1-0.30.20.3
Condit. Reinf. active minus inactive responses3.03.79.6-3.0-3.1-3.1-2.6-3.01.32.10.3-1.91.7-2.2-1.71.2-1.5-1.4-0.30.0-1.31.10.7
Condit. Reinf. active-inactive response ratio0.50.52.3-1.1-1.1-1.1-1.5-0.91.00.60.5-0.40.2-0.6-0.40.3-0.2-0.30.2-0.5-0.2-0.0-0.4
Condit. Reinf. active responses4.66.415.4-3.7-3.8-3.8-2.6-3.91.02.8-0.1-2.82.6-3.1-2.51.7-2.4-2.1-0.80.6-2.01.91.6
Condit. Reinf. inactive responses3.64.410.1-2.6-2.7-2.7-1.3-3.20.02.3-0.5-2.52.4-2.8-2.21.5-2.3-1.9-1.01.0-1.91.92.0
Condit. Reinf. lever presses6.48.830.0-5.5-5.4-5.4-4.4-4.62.62.51.5-2.42.2-2.5-1.80.8-1.8-1.20.6-0.8-1.11.10.7
Condit. Reinf. lever reinforcers received4.66.416.1-3.9-4.0-4.0-3.0-4.01.42.80.3-2.62.4-3.0-2.31.6-2.2-1.9-0.50.3-1.81.71.3
Conditioned reinforcement - actives1.41.43.7-1.4-1.1-1.1-1.9-0.41.9-0.21.70.7-0.70.50.8-0.80.91.01.5-1.61.1-1.1-1.2
Conditioned reinforcement - inactives0.30.30.91.00.90.90.80.6-0.60.5-0.70.1-0.10.1-0.10.9-0.0-0.3-0.70.4-0.30.10.0
Conditioned locomotion1.72.14.2-0.9-0.6-0.6-1.80.22.1-0.72.11.1-1.31.01.5-1.51.41.61.8-1.91.7-1.6-1.6
Patch foraging indifference point 0 sec1.93.112.1-3.5-3.3-3.3-2.8-2.71.80.91.3-1.21.1-1.1-0.7-0.0-0.8-0.31.0-0.7-0.30.40.2
Patch foraging indifference point AUC0.91.01.7-0.4-0.5-0.50.3-0.9-0.81.2-1.0-1.21.2-1.0-1.11.3-1.1-1.2-1.21.0-1.21.11.0
Delay disc. indifference point, 0s delay0.30.30.8-0.6-0.7-0.7-0.9-0.80.50.60.1-0.60.4-0.7-0.60.5-0.4-0.5-0.2-0.1-0.40.20.1
Delay disc. indifference point, 16s delay0.10.10.20.40.40.40.00.50.1-0.20.10.5-0.40.50.3-0.10.40.20.1-0.30.3-0.3-0.5
Delay disc. indifference point, 2s delay0.80.82.2-0.9-1.0-1.0-1.3-1.10.51.5-0.3-0.80.8-0.9-1.21.4-0.7-1.2-0.40.1-0.90.6-0.2
Delay disc. indifference point, 24s delay0.30.31.61.00.90.91.30.8-0.8-0.5-0.50.4-0.20.40.2-0.20.10.2-0.30.40.10.10.4
Delay disc. indifference point, 4s delay0.80.92.4-0.2-0.3-0.3-0.8-0.90.11.5-0.6-1.10.8-1.4-1.31.5-0.9-1.3-1.00.4-1.20.70.2
Delay disc. indifference point, 8s delay0.10.10.4-0.6-0.6-0.6-0.5-0.50.20.40.0-0.30.3-0.2-0.40.3-0.3-0.30.00.0-0.20.2-0.0
Indifference point function ln k1.62.24.9-1.2-0.9-0.9-1.9-0.02.1-1.12.11.1-1.20.91.4-1.81.31.62.2-1.91.6-1.5-1.5
Indifference point function log k1.62.24.9-1.2-0.9-0.9-1.9-0.02.1-1.12.11.1-1.20.91.4-1.81.31.62.2-1.91.6-1.5-1.5
Patch foraging total patch changes 0 sec1.62.59.6-3.1-3.0-3.0-2.5-2.41.60.91.1-1.11.0-1.0-0.70.1-0.8-0.40.8-0.6-0.30.40.2
Patch foraging total patch changes 12 sec1.62.14.3-1.8-1.8-1.8-0.8-2.1-0.11.6-0.5-1.81.7-1.7-1.51.3-1.6-1.4-0.80.8-1.41.41.3
Patch foraging total patch changes 18 sec1.31.74.3-2.0-2.0-2.0-1.0-2.10.21.2-0.1-1.51.5-1.5-1.20.9-1.4-1.0-0.50.5-1.01.11.1
Patch foraging total patch changes 24 sec0.60.71.8-0.6-0.6-0.6-0.8-1.10.11.3-0.5-1.00.9-1.2-1.01.2-0.9-1.1-0.50.4-1.00.80.3
Patch foraging total patch changes 6 sec0.50.73.0-1.7-1.6-1.6-1.2-1.01.00.10.9-0.20.2-0.00.1-0.3-0.10.20.7-0.60.2-0.1-0.1
Patch foraging time to switch 0 sec1.72.68.42.92.92.92.02.6-1.0-1.4-0.51.5-1.41.61.1-0.51.20.8-0.30.10.8-0.9-0.8
Patch foraging water rate 0 sec1.11.86.4-2.5-2.5-2.5-2.3-1.91.60.71.1-0.70.7-0.9-0.5-0.1-0.5-0.20.7-0.7-0.10.1-0.0
Patch foraging water rate 12 sec0.81.23.5-1.8-1.6-1.6-1.9-1.01.7-0.11.50.2-0.2-0.10.4-0.80.30.61.5-1.20.7-0.6-0.5
Patch foraging water rate 18 sec0.30.41.2-1.1-1.1-1.1-0.8-1.00.50.70.3-0.50.5-0.8-0.50.2-0.4-0.30.3-0.1-0.30.30.3
Patch foraging water rate 24 sec1.41.94.0-0.9-0.6-0.6-1.70.11.9-1.01.91.1-1.20.81.3-1.61.21.52.0-1.81.5-1.5-1.4
Patch foraging water rate 6 sec0.50.81.7-1.1-0.9-0.9-1.3-0.31.3-0.51.30.4-0.50.40.7-1.00.60.81.3-1.10.8-0.8-0.6
Seeking ratio, delayed vs. immediate footshock1.11.33.41.81.81.81.21.6-0.4-1.30.01.1-1.20.91.2-1.11.01.00.4-0.20.8-0.8-0.4
Distance traveled before self-admin0.20.20.90.60.60.60.90.4-0.8-0.2-0.60.10.10.20.10.1-0.1-0.1-0.40.5-0.20.30.4
Distance traveled after self-admin1.82.03.51.41.61.60.61.90.3-1.70.81.7-1.71.61.6-1.41.61.60.7-1.01.5-1.5-1.1
Extensor digitorum longus weight0.72.64.3-0.3-0.5-0.51.3-1.1-1.81.6-1.8-1.71.8-1.4-1.71.8-1.8-1.7-1.82.0-1.72.02.1
Bone: elastic displacement1.01.22.61.41.51.51.31.6-0.5-1.50.01.1-1.01.41.1-1.01.01.00.2-0.10.9-0.7-0.5
Bone: elastic work1.31.73.51.51.61.61.11.9-0.3-1.70.31.5-1.41.71.5-1.31.31.30.6-0.51.2-1.1-0.8
Bone: endosteal estimation1.53.45.9-1.8-2.0-2.0-0.4-2.4-0.62.2-1.0-2.32.2-2.2-2.01.7-2.1-1.9-1.21.3-1.91.91.9
Bone: endosteal perimeter1.53.16.9-2.2-2.3-2.3-0.9-2.6-0.12.1-0.5-2.22.1-2.2-1.81.4-2.0-1.6-0.80.9-1.61.71.6
Epididymis fat weight1.53.66.10.60.30.21.5-0.8-2.12.1-2.5-1.61.9-1.8-2.12.4-2.0-2.3-2.32.3-2.32.21.9
Delta time in closed arm before/after self-admin3.23.14.80.1-0.2-0.21.5-0.9-2.11.8-2.1-1.81.9-1.4-1.82.1-1.9-2.0-2.12.2-2.02.12.0
Delta time in open arm before/after self-admin0.90.92.8-1.7-1.7-1.7-1.2-1.50.70.80.4-0.90.8-1.0-0.60.2-0.7-0.40.1-0.1-0.40.40.5
Diff in mean of infusions in LGA sessions1.01.13.81.91.91.91.71.4-1.3-0.4-1.10.6-0.30.50.10.30.2-0.2-1.00.7-0.20.10.1
Delay discount exponential model param0.10.10.4-0.1-0.1-0.10.10.10.1-0.50.40.2-0.20.20.5-0.60.20.50.4-0.20.4-0.20.1
Extinction: sum of active levers before priming0.10.10.30.50.40.40.50.1-0.50.1-0.6-0.10.2-0.3-0.30.4-0.2-0.4-0.50.4-0.40.30.2
Active lever presses in extinction session 63.02.96.6-1.3-1.1-1.0-2.5-0.12.6-1.22.41.2-1.31.11.2-1.81.51.62.1-2.31.7-1.8-1.9
Bone: final force0.10.10.3-0.6-0.6-0.60.3-0.3-0.40.2-0.1-0.30.40.1-0.10.1-0.3-0.0-0.10.3-0.10.30.5
Bone: final moment0.10.20.6-0.8-0.8-0.80.2-0.5-0.30.3-0.1-0.50.5-0.1-0.20.1-0.5-0.1-0.10.4-0.20.50.7
Food consumed during 24 hour testing period0.81.03.4-1.4-1.3-1.3-1.8-1.21.6-0.11.4-0.0-0.1-0.80.4-0.90.10.61.3-1.10.5-0.5-0.1
Glucose0.10.10.30.20.20.2-0.30.40.4-0.40.30.5-0.50.40.4-0.30.50.40.3-0.40.4-0.5-0.5
Heart weight0.30.41.7-1.3-1.3-1.3-1.0-0.90.70.50.7-0.30.2-0.3-0.1-0.0-0.10.20.4-0.40.1-0.00.1
Delay discount hyperbolic model param0.20.20.80.10.10.10.30.40.0-0.80.40.4-0.40.50.7-0.90.40.80.5-0.30.6-0.40.0
Intermittent access intake day 1-15 change0.60.61.8-1.1-0.9-0.9-1.3-0.41.2-0.11.10.4-0.30.30.4-0.30.40.51.0-1.00.6-0.6-0.7
Intermittent access intake escalation0.80.82.3-1.2-1.1-1.1-1.5-0.51.4-0.21.20.4-0.30.30.5-0.40.50.61.1-1.10.7-0.7-0.8
Intermittent access intake escalation 20.20.20.7-0.8-0.8-0.8-0.7-0.60.40.50.3-0.20.3-0.3-0.20.3-0.2-0.20.2-0.2-0.10.1-0.0
Intermitt. access day 1 inactive lever presses0.30.31.01.00.90.90.80.5-0.70.5-0.70.0-0.0-0.0-0.10.8-0.1-0.4-0.70.5-0.40.20.1
Intermitt. access day 15 inactive lever presses0.30.30.60.30.40.4-0.10.60.5-0.20.60.7-0.80.50.8-0.40.70.70.5-0.60.7-0.7-0.6
Intermitt. access escalation Index0.10.10.2-0.5-0.5-0.5-0.1-0.30.10.10.2-0.20.1-0.10.1-0.2-0.10.10.2-0.10.10.10.3
Intermittent access day 1 total infusions0.30.40.9-0.9-1.0-1.0-0.2-0.9-0.00.7-0.1-0.70.7-0.7-0.50.3-0.6-0.4-0.20.3-0.40.50.7
Intermittent access day 15 total infusions0.50.51.8-1.3-1.2-1.2-1.2-0.71.10.21.00.0-0.10.10.3-0.20.20.50.8-0.80.5-0.4-0.3
Intermittent access terminal intake (last 3 days)0.30.41.5-1.2-1.2-1.2-0.9-0.80.70.50.6-0.30.2-0.2-0.00.1-0.10.10.4-0.40.1-0.00.1
Intermittent access total infusions0.20.20.7-0.8-0.8-0.8-0.4-0.60.30.50.3-0.30.3-0.3-0.10.1-0.2-0.00.1-0.1-0.00.20.3
Intermittent access day 1 locomotion0.20.20.40.10.10.1-0.10.30.3-0.30.50.3-0.50.40.6-0.60.50.60.4-0.40.6-0.5-0.3
Intermittent access day 15 total locomotion0.70.71.6-1.0-0.9-0.8-1.2-0.31.3-0.21.30.4-0.50.40.7-0.80.60.91.1-1.10.9-0.8-0.6
Intermittent access total locomotion0.10.10.4-0.6-0.6-0.6-0.5-0.40.40.20.4-0.10.0-0.10.1-0.20.00.20.3-0.30.2-0.1-0.0
Intermittent access standard deviation0.10.20.3-0.2-0.2-0.2-0.0-0.4-0.20.6-0.3-0.50.4-0.5-0.40.5-0.4-0.4-0.50.3-0.40.40.4
Left kidney weight1.64.68.8-1.6-1.9-1.9-0.4-2.5-0.73.0-1.4-2.52.4-2.7-2.52.5-2.4-2.4-1.61.6-2.32.22.0
Right kidney weight1.13.15.5-1.1-1.4-1.4-0.1-2.0-0.82.3-1.3-2.02.0-2.3-2.22.1-2.0-2.0-1.51.5-1.91.91.9
Cocaine induced anxiety0.60.72.61.61.51.51.31.3-0.9-0.5-0.60.5-0.50.60.30.20.40.1-0.50.40.1-0.2-0.1
Post-drug Anxiety0.20.20.60.70.70.70.80.5-0.70.2-0.6-0.00.10.1-0.20.5-0.1-0.3-0.40.5-0.30.20.2
Baseline Anxiety0.70.72.5-1.6-1.5-1.5-1.2-1.30.60.70.3-0.70.7-0.7-0.60.2-0.6-0.40.2-0.1-0.40.40.3
Tail length5.215.923.4-2.4-2.9-3.00.4-4.4-2.44.5-3.2-4.74.8-4.8-4.64.3-4.7-4.5-3.73.7-4.54.54.4
Length with tail2.910.515.7-1.1-1.7-1.70.8-3.0-2.43.8-3.1-3.73.7-3.8-4.03.8-3.8-3.8-3.33.3-3.83.73.5
Length without tail0.20.41.01.01.01.00.21.00.1-0.2-0.00.7-0.70.70.2-0.00.70.30.1-0.30.3-0.6-0.8
Times rat made contact with spout1.01.22.20.20.0-0.01.2-0.5-1.40.9-1.3-1.01.1-1.1-1.01.1-1.2-1.1-1.21.4-1.21.31.5
Lifetime Intake0.20.21.0-1.0-1.0-1.0-0.7-0.70.50.50.4-0.30.3-0.3-0.20.1-0.2-0.00.2-0.2-0.00.10.1
Liver weight, left1.72.74.50.60.30.21.7-0.6-2.11.5-2.1-1.61.6-1.5-1.71.7-1.7-1.8-2.12.1-1.91.91.9
Liver weight, right3.45.610.31.41.01.02.7-0.5-3.12.1-3.2-2.02.1-2.0-2.42.6-2.3-2.6-3.13.1-2.72.62.6
Locomotor activity0.30.51.7-1.3-1.2-1.3-0.9-1.00.70.20.7-0.20.2-0.60.2-0.5-0.20.30.9-0.40.2-0.00.5
Locomotor testing distance0.91.44.3-2.0-2.1-2.1-1.6-1.90.81.10.5-1.11.0-1.5-0.60.3-1.0-0.50.4-0.1-0.50.60.8
Locomotor testing rearing1.21.93.5-1.2-1.4-1.4-0.5-1.8-0.41.7-0.8-1.81.6-1.9-1.51.3-1.6-1.4-0.91.0-1.51.41.4
Locomotion in novel chamber1.21.53.1-1.0-0.8-0.8-1.20.11.6-1.11.70.9-1.00.81.4-1.71.11.41.6-1.51.4-1.3-0.9
Locomotion in novel chamber post-restriction1.92.36.7-1.8-1.5-1.4-2.6-0.42.4-0.32.10.9-0.90.91.0-0.91.11.12.1-2.01.3-1.4-1.8
Fecal boli incidents, locomotor time 10.70.81.8-0.6-0.5-0.5-1.1-0.11.3-0.61.30.6-0.80.30.8-1.20.81.01.2-1.21.0-0.9-0.6
Change in fecal boli incidents, locomotor task0.40.41.51.21.21.21.01.0-0.7-0.3-0.60.4-0.30.6-0.00.30.3-0.0-0.50.3-0.0-0.1-0.3
Time >=10cm from walls, locomotor time 11.01.02.9-1.2-1.1-1.1-1.7-0.41.6-0.11.40.5-0.50.50.5-0.70.70.71.5-1.30.8-0.9-1.0
Bouts of movement, locomotor time 10.00.00.20.00.00.0-0.40.00.4-0.10.30.1-0.2-0.0-0.0-0.20.20.1-0.0-0.30.1-0.3-0.3
Total resting periods, locomotor time 10.40.40.70.30.40.4-0.30.50.6-0.80.70.7-0.80.60.6-0.80.80.80.5-0.70.7-0.8-0.7
Rest time, locomotor task time 10.60.71.41.11.21.2-0.21.10.5-0.90.41.0-1.10.60.7-0.71.00.70.3-0.70.7-0.9-1.0
Distance moved, locomotor task time 11.51.72.7-1.2-1.3-1.40.4-1.4-0.91.3-0.9-1.51.6-1.1-1.21.3-1.5-1.2-1.01.2-1.31.51.6
Vertical activity count, locomotor time 11.31.32.8-1.6-1.7-1.7-0.2-1.5-0.41.2-0.5-1.31.4-0.8-1.11.2-1.3-1.0-0.70.8-0.91.21.1
Time >=10cm from walls, locomotor time 20.30.31.4-0.8-0.8-0.8-1.2-0.80.80.70.4-0.40.2-0.6-0.60.4-0.2-0.30.1-0.4-0.20.0-0.2
Bouts of movement, locomotor time 20.50.51.2-0.6-0.6-0.6-0.6-0.90.01.1-0.5-0.80.8-0.8-0.91.1-0.8-1.0-0.50.4-0.90.70.2
Total resting periods, locomotor time 20.40.41.2-0.3-0.3-0.3-0.5-0.6-0.00.9-0.5-0.60.6-0.6-0.81.1-0.6-0.9-0.60.4-0.80.5-0.0
Rest time, locomotor task time 20.91.03.11.71.71.71.71.6-1.1-1.1-0.70.7-0.61.00.5-0.30.50.3-0.40.50.3-0.2-0.0
Distance moved, locomotor task time 21.41.64.0-2.0-2.0-2.0-1.6-2.00.81.60.2-1.31.2-1.5-1.10.9-1.0-0.9-0.30.0-0.90.70.5
Vertical activity count, locomotor time 21.71.83.7-1.8-1.9-1.9-0.8-1.9-0.01.6-0.3-1.61.6-1.4-1.51.3-1.4-1.2-0.90.7-1.11.21.0
Light reinforcement 10.61.13.91.81.71.72.01.2-1.5-0.4-1.20.2-0.10.2-0.10.3-0.1-0.3-1.01.0-0.40.40.6
Light reinforcement 20.20.30.50.40.40.40.10.60.2-0.70.40.6-0.60.50.5-0.70.60.60.3-0.40.6-0.6-0.3
Bone: marrow area1.53.25.3-1.7-1.9-1.9-0.2-2.3-0.72.1-1.1-2.22.2-2.1-2.01.7-2.1-1.9-1.31.4-1.91.91.9
Bone: maximum diameter1.42.56.4-2.4-2.5-2.5-1.2-2.40.21.8-0.1-1.81.8-1.6-1.51.1-1.6-1.2-0.50.6-1.21.31.3
Bone: maximum force0.10.21.0-1.0-1.0-1.00.1-0.6-0.20.30.0-0.50.5-0.1-0.20.1-0.4-0.1-0.10.3-0.10.40.7
Bone: maximum moment0.20.41.4-1.2-1.2-1.2-0.0-0.9-0.20.40.0-0.60.7-0.3-0.30.1-0.6-0.1-0.10.3-0.20.50.8
Mean time between licks in bursts4.46.211.8-2.3-2.6-2.6-1.4-3.4-0.23.3-1.2-3.02.8-3.4-2.92.5-2.8-2.7-1.41.5-2.62.42.1
Mean num. licks in bursts1.21.55.1-2.3-2.1-2.1-2.1-1.71.60.21.4-0.40.4-0.8-0.0-0.6-0.30.31.1-0.90.3-0.10.0
Cd content in liver0.70.81.60.50.20.21.0-0.1-1.20.7-1.2-0.80.8-0.6-0.91.0-0.8-0.9-1.21.2-1.01.01.0
Co content in liver1.31.53.1-1.1-1.3-1.3-0.6-1.7-0.21.6-0.6-1.51.4-1.8-1.51.2-1.4-1.3-0.80.7-1.31.21.1
Cu content in liver1.01.22.8-0.4-0.6-0.6-0.5-1.3-0.21.6-0.8-1.31.2-1.7-1.41.4-1.2-1.4-1.00.7-1.31.10.8
Fe content in liver0.00.10.20.0-0.0-0.00.1-0.0-0.30.2-0.3-0.10.2-0.0-0.30.4-0.2-0.3-0.40.3-0.30.20.1
K content in liver0.30.30.50.50.40.40.5-0.2-0.70.6-0.7-0.50.5-0.7-0.50.7-0.6-0.6-0.60.7-0.60.60.6
Mg content in liver0.10.10.3-0.4-0.3-0.3-0.5-0.40.30.40.1-0.30.2-0.3-0.20.3-0.2-0.3-0.0-0.1-0.20.1-0.1
Mn content in liver1.82.13.61.61.81.90.61.90.3-1.70.71.8-1.71.61.5-1.31.61.40.9-0.91.4-1.4-1.3
Na content in liver0.30.31.1-0.2-0.1-0.1-1.0-0.11.0-0.10.70.4-0.40.10.4-0.30.40.30.6-0.80.4-0.6-0.9
Rb content in liver0.50.71.8-1.3-1.3-1.3-0.6-1.30.10.70.1-0.90.9-0.9-0.70.3-0.8-0.5-0.10.3-0.50.70.8
Se content in liver1.82.28.52.92.92.91.72.3-0.9-1.2-0.61.3-1.31.10.8-0.41.10.6-0.30.00.6-0.8-0.8
Sr content in liver0.50.50.60.10.20.3-0.40.50.7-0.70.70.8-0.80.70.8-0.80.80.80.8-0.80.8-0.8-0.8
Zn content in liver1.82.06.9-2.6-2.6-2.6-2.5-2.11.61.01.0-1.00.8-1.1-0.70.2-0.7-0.40.5-0.7-0.30.20.0
Bone: minimum diameter2.24.15.9-1.0-1.3-1.30.7-2.0-1.62.3-1.8-2.42.4-2.2-2.32.2-2.4-2.2-2.02.1-2.32.42.4
Time in familiar zone, hab. session 10.30.30.50.30.20.20.6-0.2-0.70.6-0.7-0.60.5-0.6-0.60.7-0.6-0.6-0.60.7-0.60.60.7
Time in novel zone, hab. session 10.00.00.10.10.10.10.30.2-0.3-0.2-0.2-0.00.10.2-0.00.0-0.0-0.1-0.20.2-0.10.10.1
Total zone transitions, hab. session 10.60.91.4-0.3-0.1-0.1-0.70.51.0-1.01.20.9-0.91.01.1-1.11.01.21.1-1.11.2-1.1-0.9
Total locomotion distance, hab. session 11.21.83.30.80.50.51.3-0.3-1.61.3-1.8-1.21.2-1.1-1.41.6-1.3-1.5-1.81.7-1.51.41.3
Locomotion velocity, hab. session 10.71.01.80.50.30.30.9-0.3-1.21.0-1.3-0.90.9-0.9-1.11.3-1.0-1.2-1.31.2-1.21.11.0
Time in familiar zone, hab. session 20.91.02.4-1.5-1.5-1.5-0.4-1.5-0.10.9-0.1-1.21.1-1.1-0.80.5-1.1-0.5-0.20.5-0.60.91.2
Time in novel zone, hab. session 20.70.71.41.11.11.1-0.21.10.5-0.80.41.0-1.10.80.8-0.61.00.60.4-0.70.7-1.0-1.2
Total zone transitions, hab. session 21.11.44.2-1.1-0.9-0.9-2.1-0.32.0-0.51.70.7-0.80.50.8-1.00.91.01.4-1.61.0-1.2-1.3
Total locomotion distance, hab. session 21.31.72.70.1-0.1-0.20.5-0.9-1.11.6-1.5-1.41.3-1.6-1.61.6-1.4-1.6-1.61.4-1.61.41.3
Locomotion velocity, hab. session 21.52.13.40.3-0.0-0.00.6-0.9-1.21.7-1.7-1.51.5-1.7-1.71.8-1.5-1.8-1.81.6-1.81.61.4
Novel to familiar place preference ratio0.10.10.3-0.1-0.0-0.0-0.50.10.5-0.00.20.2-0.30.20.2-0.10.30.10.1-0.40.1-0.3-0.6
Novelty place preference0.10.10.40.10.10.1-0.50.20.5-0.00.20.2-0.30.10.2-0.20.30.10.1-0.40.1-0.4-0.6
Time in novel zone, NPP test0.10.10.5-0.1-0.1-0.1-0.70.00.6-0.00.40.2-0.30.10.2-0.20.30.10.3-0.50.2-0.4-0.6
Total zone transitions, NPP test0.50.71.10.00.10.2-0.90.41.1-0.61.00.8-0.90.50.8-0.90.90.91.0-1.10.9-1.0-1.0
Total locomotion distance, NPP test0.91.32.51.31.01.00.90.1-1.21.2-1.6-0.80.7-1.1-1.21.4-0.8-1.4-1.51.2-1.31.00.7
Locomotion velocity, NPP test1.01.42.91.71.41.41.20.4-1.31.1-1.7-0.60.5-1.0-1.11.4-0.7-1.4-1.61.3-1.30.90.6
Intraocular pressure0.91.32.2-0.8-0.5-0.5-1.30.31.5-1.01.51.0-1.01.11.2-1.21.11.21.4-1.41.2-1.2-1.3
Delta distance traveled before/after self-admin0.80.81.30.00.20.2-0.60.61.0-0.81.10.9-1.10.80.9-1.01.11.20.9-1.21.1-1.1-1.0
Delta ambulatory time before/after self-admin1.31.52.40.20.40.4-0.90.81.4-1.11.41.2-1.41.11.2-1.21.41.41.1-1.51.4-1.5-1.5
Parametrial fat weight1.32.44.50.30.10.11.8-0.5-2.11.2-2.1-1.41.6-0.9-1.71.8-1.6-1.7-2.02.1-1.71.81.8
Pavlov. Cond. lever latency0.50.61.91.21.31.30.81.4-0.4-0.8-0.20.8-0.81.10.6-0.30.80.4-0.1-0.10.5-0.5-0.7
Pavlov. Cond. magazine entry latency1.31.75.0-2.2-2.2-2.2-1.5-2.10.71.20.3-1.31.2-1.4-1.10.6-1.1-0.8-0.00.1-0.80.80.8
Pavlov. Cond. change in total contacts0.40.51.2-0.8-0.9-0.9-1.0-1.10.60.90.1-0.70.5-1.1-0.60.4-0.6-0.5-0.1-0.1-0.50.30.2
Pavlov. Cond. index score1.41.84.9-2.0-2.1-2.1-1.4-2.20.51.30.2-1.41.4-1.8-1.20.6-1.3-0.9-0.10.2-0.91.01.1
Pavlov. Cond. latency score1.31.74.6-2.0-2.1-2.1-1.4-2.10.61.20.2-1.31.3-1.7-1.10.6-1.2-0.80.00.2-0.80.91.0
Pavlov. Cond. lever contacts0.80.92.4-1.1-1.2-1.2-0.7-1.50.11.1-0.1-1.11.1-1.6-1.00.7-1.1-0.8-0.20.4-0.80.91.0
Pavlov. Cond. magazine entry number1.31.65.22.32.32.31.82.1-1.0-1.1-0.61.1-1.11.30.9-0.40.90.6-0.30.20.5-0.6-0.6
Pavlov. Cond. intertrial magazine entries0.91.14.12.02.02.01.11.6-0.5-0.8-0.30.9-1.00.60.8-0.40.80.50.0-0.10.4-0.6-0.5
Pavlov. Cond. lever-magazine prob. diff.1.21.43.9-1.8-1.9-1.8-1.1-2.00.41.10.1-1.31.2-1.6-1.10.6-1.2-0.8-0.10.3-0.80.91.0
Pavlov. Cond. response bias0.70.92.2-1.1-1.2-1.2-0.7-1.50.11.0-0.1-1.11.0-1.5-1.00.6-1.0-0.8-0.20.4-0.80.80.9
Pavlov. Cond. lever latency6.58.831.35.65.55.54.94.4-3.2-2.2-2.02.0-1.82.21.4-0.41.40.8-1.11.30.7-0.6-0.2
Pavlov. Cond. magazine entry latency1.92.28.3-2.9-2.7-2.7-2.6-1.72.00.31.7-0.30.2-0.10.1-0.50.10.41.2-1.30.5-0.4-0.6
Pavlov. Cond. change in total contacts4.46.121.8-4.6-4.4-4.4-4.7-3.53.21.62.1-1.31.0-1.6-0.80.0-0.7-0.41.3-1.6-0.2-0.0-0.5
Pavlov. Cond. index score5.26.724.4-4.9-4.8-4.8-4.5-3.73.01.72.0-1.51.3-1.6-1.00.2-0.9-0.51.2-1.4-0.30.2-0.2
Pavlov. Cond. latency score4.75.921.5-4.6-4.5-4.5-4.3-3.43.01.42.0-1.31.1-1.3-0.80.1-0.7-0.31.2-1.5-0.10.1-0.4
Pavlov. Cond. lever contacts6.89.333.7-5.8-5.7-5.7-5.0-4.63.22.32.1-2.11.9-2.2-1.40.5-1.5-0.81.2-1.3-0.60.60.2
Pavlov. Cond. magazine entry number2.83.413.23.33.13.13.62.1-2.8-0.4-2.10.3-0.20.4-0.10.6-0.1-0.4-1.51.8-0.60.60.9
Pavlov. Cond. intertrial magazine entries1.82.33.30.2-0.1-0.11.1-1.0-1.61.7-1.7-1.71.6-1.7-1.71.8-1.7-1.7-1.71.8-1.81.81.8
Pavlov. Cond. lever-magazine prob. diff.4.96.222.1-4.7-4.6-4.6-4.4-3.62.91.81.8-1.61.4-1.6-1.10.4-1.0-0.61.0-1.3-0.40.3-0.2
Pavlov. Cond. response bias6.99.434.6-5.9-5.8-5.7-5.1-4.53.42.12.3-2.01.7-2.0-1.20.2-1.3-0.61.3-1.5-0.40.50.1
Time in closed arm before self-admin3.03.46.3-0.7-0.4-0.4-1.80.52.3-1.72.51.7-1.81.32.1-2.41.92.32.4-2.32.2-2.1-1.7
Time in closed arm after self-admin1.31.32.50.91.01.00.41.30.3-1.30.81.4-1.41.31.6-1.31.31.51.0-0.91.4-1.2-0.8
Time in open arm before self-admin1.21.43.71.91.71.71.91.1-1.70.1-1.7-0.20.20.1-0.51.0-0.3-0.9-1.41.2-0.80.60.3
Time in open arm after self-admin2.02.23.5-0.8-1.1-1.10.2-1.5-1.01.6-1.3-1.81.8-1.5-1.91.6-1.7-1.8-1.51.4-1.71.71.4
Bone: periosteal estimation1.42.85.1-1.9-2.1-2.1-0.4-2.3-0.52.0-0.8-2.02.0-1.9-1.71.4-1.9-1.6-1.01.2-1.61.71.8
Bone: periosteal perimeter1.42.35.0-1.9-2.1-2.1-0.6-2.2-0.21.6-0.4-1.81.8-1.8-1.41.0-1.7-1.2-0.60.9-1.31.51.6
Bone: post-yield work0.30.41.8-1.3-1.3-1.3-0.1-0.8-0.00.20.2-0.50.6-0.2-0.2-0.0-0.5-0.00.10.2-0.10.40.7
Progressive ratio test 1 active lever presses0.20.20.50.70.70.70.50.7-0.2-0.1-0.10.4-0.40.50.30.10.40.2-0.0-0.00.2-0.2-0.3
Progressive ratio test 1 breakpoint0.10.10.40.60.60.60.50.5-0.40.1-0.30.2-0.20.30.10.30.2-0.0-0.20.20.0-0.0-0.2
Progressive ratio test 1 inactive lever presses0.10.10.5-0.4-0.4-0.4-0.1-0.3-0.10.7-0.2-0.30.4-0.2-0.30.7-0.3-0.4-0.20.2-0.30.30.2
Progressive ratio test 2 active lever presses0.50.51.5-1.2-1.2-1.2-0.8-1.10.41.00.1-0.60.7-0.6-0.60.8-0.6-0.5-0.00.0-0.40.40.3
Progressive ratio test 2 breakpoint0.50.61.6-1.2-1.3-1.3-0.8-1.10.31.10.1-0.70.7-0.7-0.60.8-0.6-0.5-0.10.1-0.50.50.3
Progressive ratio test 2 inactive lever presses0.20.20.8-0.9-0.8-0.8-0.6-0.50.50.40.60.10.00.00.20.10.10.30.4-0.40.3-0.10.0
Incentive Sensitization - Responses1.31.33.7-1.9-1.9-1.9-1.3-1.70.61.30.2-1.11.1-1.0-0.90.9-0.9-0.7-0.10.1-0.60.70.6
Incentive Sensitization - Breakpoint1.11.13.5-1.9-1.9-1.9-1.3-1.60.71.10.4-0.90.9-0.9-0.70.7-0.7-0.50.1-0.1-0.40.50.4
Sum of active levers in priming session hrs 5-60.10.10.30.30.20.3-0.10.20.2-0.50.10.3-0.3-0.00.0-0.40.20.20.2-0.20.2-0.2-0.1
Progressive ratio0.30.30.7-0.2-0.0-0.0-0.50.30.7-0.50.70.5-0.60.50.7-0.60.60.60.9-0.70.6-0.7-0.7
Food seeking constrained by brief footshock1.11.42.7-1.3-1.4-1.4-0.8-1.60.01.5-0.5-1.21.3-1.5-1.31.2-1.3-1.3-0.80.6-1.21.10.8
Seeking ratio, punishment vs. effort1.72.13.1-0.9-1.1-1.1-0.1-1.6-0.81.8-1.1-1.61.7-1.7-1.71.7-1.7-1.7-1.51.3-1.71.61.4
Retroperitoneal fat weight4.916.130.32.11.41.34.5-0.7-5.33.6-5.5-3.43.6-2.9-4.14.8-3.8-4.5-5.45.2-4.54.44.2
Reaction time number correct1.21.73.00.10.30.3-0.90.81.4-1.71.51.4-1.51.01.4-1.71.41.51.5-1.51.5-1.5-1.3
Reaction time mean minus median0.70.91.9-1.4-1.4-1.4-0.5-1.4-0.01.0-0.2-1.11.1-0.9-0.90.8-1.0-0.8-0.50.5-0.80.90.8
Reaction time mean minus median AUC0.40.51.9-1.4-1.3-1.3-0.9-1.10.60.40.4-0.60.5-0.5-0.3-0.0-0.4-0.10.2-0.1-0.20.30.3
Reaction time num false alarms0.81.13.41.71.51.51.80.7-1.60.3-1.5-0.20.3-0.3-0.60.9-0.5-0.8-1.21.2-0.80.70.7
Reaction time num false alarms AUC0.50.62.41.51.41.41.30.8-1.00.1-1.00.0-0.0-0.1-0.20.5-0.1-0.4-0.80.7-0.40.30.3
Reaction time trials correct on left1.21.73.00.10.30.3-0.90.81.4-1.71.51.4-1.51.01.4-1.71.41.51.5-1.51.5-1.5-1.3
Reaction time trials on left1.21.73.00.10.30.3-0.90.81.4-1.71.51.5-1.51.01.4-1.71.41.51.5-1.51.5-1.5-1.3
Reaction time mean0.60.82.00.40.30.31.40.1-1.40.6-1.3-0.70.8-0.1-0.81.0-0.7-0.9-1.41.3-0.91.00.9
Reaction time mean AUC0.50.72.40.90.70.71.60.5-1.40.2-1.2-0.30.40.1-0.50.7-0.4-0.6-1.21.1-0.60.70.7
Median of all reaction times0.50.72.81.00.80.81.70.6-1.50.2-1.3-0.30.40.3-0.50.7-0.4-0.6-1.31.1-0.60.70.7
Reaction time omissions0.20.30.60.20.10.10.70.0-0.70.5-0.8-0.40.5-0.2-0.50.6-0.4-0.6-0.70.7-0.60.60.5
Reaction time false alarm rate0.91.32.91.41.31.21.70.5-1.60.8-1.6-0.50.6-0.4-0.81.3-0.7-1.0-1.41.4-1.00.90.8
Reaction time premature initiation rate3.64.87.1-2.0-2.3-2.3-0.1-2.6-1.12.6-1.4-2.72.7-2.3-2.42.2-2.5-2.3-1.81.8-2.22.42.4
Reaction time premature initiations1.31.84.0-1.9-2.0-2.0-0.7-1.9-0.11.3-0.3-1.51.5-1.4-1.31.0-1.4-1.1-0.70.7-1.11.21.4
Std. dev. reaction times1.31.82.6-0.9-1.0-1.00.3-1.3-1.01.6-1.2-1.61.6-1.2-1.51.6-1.5-1.5-1.51.3-1.51.51.4
Reaction time trials completed1.21.73.00.10.30.3-0.90.81.4-1.71.51.5-1.51.01.4-1.71.41.51.5-1.51.5-1.5-1.3
Reaction time trials AUC0.91.22.20.00.20.2-0.80.71.2-1.41.31.2-1.20.81.2-1.51.21.31.3-1.31.2-1.3-1.1
Run reversals in cocaine runway, females6.76.510.0-0.2-0.6-0.61.9-1.7-2.82.4-2.9-2.72.9-2.3-2.92.9-2.9-2.9-3.23.1-2.93.02.9
Run reversals in cocaine runway, males0.00.00.10.10.10.10.30.2-0.2-0.3-0.10.1-0.00.30.00.00.00.1-0.20.10.10.00.1
Latency to leave start box in cocaine runway1.01.12.81.71.51.51.30.9-1.30.3-1.6-0.10.3-0.0-0.71.1-0.3-1.1-1.31.1-0.90.60.0
Latency to leave start box in cocaine runway, F1.51.73.81.41.11.11.20.3-1.51.0-2.0-0.80.9-0.7-1.41.8-1.0-1.7-1.71.5-1.51.10.5
Latency to leave start box in cocaine runway, M0.50.51.00.50.60.60.20.90.2-0.90.40.9-0.81.00.8-0.70.80.70.4-0.50.7-0.7-0.7
Std. dev. time between licks in bursts2.93.46.3-1.0-1.3-1.3-0.2-2.1-0.82.5-1.4-2.22.1-2.4-2.32.2-2.2-2.2-1.41.5-2.22.01.7
Total sessions with >9 infusions0.80.92.9-1.7-1.6-1.5-1.7-0.91.40.01.30.0-0.10.10.3-0.60.20.51.1-1.00.6-0.5-0.5
Short access day 1 total inactive lever presses0.10.20.50.70.70.70.60.6-0.3-0.3-0.10.4-0.40.30.3-0.20.30.3-0.20.00.2-0.2-0.1
Short access day 10 total inactive lever presses0.10.10.30.40.50.50.20.50.1-0.40.20.5-0.50.40.4-0.20.40.40.2-0.20.4-0.4-0.3
Short access day 1 total infusions0.70.82.6-1.6-1.6-1.6-1.2-1.40.70.90.4-0.70.7-0.7-0.60.3-0.6-0.40.3-0.1-0.40.40.3
Short access day 10 total infusions0.40.51.2-0.9-0.9-0.9-0.5-1.00.11.1-0.1-0.80.7-0.8-0.70.7-0.7-0.6-0.40.3-0.60.60.5
Short access total infusions0.40.41.0-0.9-1.0-1.0-0.4-1.00.00.8-0.1-0.70.7-0.7-0.60.5-0.7-0.5-0.20.3-0.50.60.5
Short access day 1 locomotion1.61.74.2-1.2-0.9-0.9-2.0-0.12.0-0.61.80.9-1.00.91.1-1.21.11.21.6-1.81.3-1.4-1.6
Short access day 10 total locomotion0.10.10.4-0.4-0.4-0.4-0.7-0.40.50.60.3-0.30.1-0.2-0.00.1-0.00.00.1-0.30.0-0.1-0.2
Short access total locomotion0.10.10.3-0.2-0.1-0.1-0.50.00.50.20.40.1-0.20.20.2-0.20.30.20.3-0.40.3-0.3-0.5
One hour access (0.3 mA shock)0.60.72.7-1.6-1.6-1.6-1.4-1.11.00.60.8-0.30.3-0.4-0.1-0.0-0.20.10.6-0.60.1-0.0-0.0
Compulsive drug intake0.60.61.0-0.10.10.1-0.80.40.9-0.70.90.9-0.80.70.8-0.80.90.81.0-1.00.9-0.9-1.0
One hour access (shock baseline)0.40.41.5-1.2-1.2-1.2-0.9-1.00.60.70.4-0.50.5-0.5-0.30.3-0.4-0.20.2-0.2-0.20.20.2
Social response proportion0.40.41.00.80.60.61.00.2-1.00.5-0.9-0.30.3-0.4-0.40.7-0.4-0.6-0.90.8-0.60.60.6
Social responses1.31.72.90.70.40.41.3-0.4-1.61.3-1.7-1.11.2-1.2-1.31.5-1.3-1.5-1.61.6-1.51.41.5
Social time1.62.16.82.62.62.61.32.3-0.4-1.4-0.21.6-1.51.21.0-0.61.30.8-0.1-0.30.8-1.0-1.1
Soleus weight2.05.88.3-0.2-0.6-0.61.7-1.7-2.52.6-2.7-2.62.7-2.4-2.72.7-2.7-2.7-2.72.8-2.72.92.9
Bone: stiffness0.40.71.1-0.2-0.3-0.40.8-0.4-1.10.8-1.0-0.80.9-0.4-0.90.9-0.8-0.8-1.01.1-0.81.01.0
Tibialis anterior weight0.31.21.7-0.8-1.0-1.00.1-1.2-0.71.3-0.8-1.31.3-1.1-1.21.2-1.3-1.2-1.01.0-1.21.21.2
Time to tail flick, vehicle, before self-admin0.10.10.60.0-0.0-0.00.70.1-0.3-0.50.20.1-0.10.10.3-0.80.10.50.20.10.3-0.00.5
Time to tail flick, vehicle, after self-admin0.80.82.4-1.5-1.4-1.4-1.5-0.81.3-0.31.20.2-0.10.00.4-0.80.30.61.1-0.90.6-0.5-0.4
Time to tail flick, test, before self-admin0.60.61.2-0.4-0.5-0.60.1-0.8-0.40.8-0.6-0.90.9-0.9-1.10.8-0.9-0.9-0.90.7-0.90.90.7
Time to tail flick, test, after self-admin1.11.12.2-0.2-0.4-0.4-0.0-1.0-0.61.5-1.0-1.21.1-1.3-1.21.4-1.2-1.4-1.10.9-1.31.10.8
Delta time to tail flick, vehicle, before/after SA0.80.84.1-1.4-1.2-1.2-2.0-0.61.50.11.00.2-0.20.20.1-0.10.40.10.9-1.10.3-0.6-1.2
Delta time to tail flick, test, before/after SA0.10.10.50.70.70.70.00.5-0.00.1-0.20.3-0.30.20.20.20.2-0.1-0.0-0.1-0.0-0.2-0.5
Tibia length1.13.28.4-1.9-1.6-1.6-2.9-0.62.8-0.92.51.0-1.10.71.3-1.71.31.52.2-2.41.6-1.7-1.8
Ambulatory time before self-admin0.30.30.90.90.90.90.80.9-0.4-0.6-0.10.6-0.50.80.7-0.30.50.40.20.00.4-0.3-0.2
Ambulatory time after self-admin3.03.35.21.61.81.80.32.20.8-2.01.32.2-2.32.12.0-1.82.22.11.2-1.52.0-2.0-1.7
Bone: tissue strength2.12.03.10.20.40.4-0.61.21.1-1.81.41.6-1.61.71.7-1.61.61.61.4-1.51.7-1.6-1.6
Total heroin consumption0.10.10.2-0.2-0.2-0.2-0.5-0.10.5-0.30.40.1-0.2-0.1-0.0-0.40.20.20.2-0.40.2-0.3-0.1
Bone: trabecular number0.60.92.20.70.80.81.31.2-0.5-1.50.30.9-0.81.21.3-1.30.81.30.6-0.11.0-0.60.1
Bone: trabecular spacing0.30.42.6-0.7-0.7-0.7-1.6-0.51.30.30.70.1-0.2-0.1-0.00.00.3-0.00.6-0.90.2-0.5-1.0
Bone: trabecular thickness0.30.41.40.20.10.11.1-0.2-1.10.1-0.7-0.50.6-0.4-0.40.1-0.6-0.3-0.60.9-0.50.81.2
Bone: trabecular tissue density1.92.75.41.10.80.81.7-0.2-2.11.6-2.3-1.31.4-1.2-1.72.2-1.5-1.9-2.32.0-1.91.71.5
Water consumed over 24 hours0.40.51.41.11.11.11.20.9-0.7-0.7-0.20.6-0.50.40.6-0.50.40.50.10.20.4-0.20.3
Number of responses in last shaping day0.80.81.3-0.6-0.8-0.80.1-1.0-0.51.1-0.6-1.01.0-1.1-0.90.8-1.0-0.9-0.80.8-0.91.01.1