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Breakpoint value in progressive ratio session

Breakpoint value in the progressive ratio session after the first set of self admin sessions

Tags: Behavior · Heroin · Progressive ratio

Project: u01_peter_kalivas

5 loci · 5 genes with independent associations · 5 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr4	15395730	16429926	1	1	5.69e-08	4.71e-02	6.40e-01	LOC134486553
2	chr8	130995414	132376607	1	1	9.56e-08	2.99e-01	1.00e+00	Clec3b
3	chr9	83390749	84777604	1	1	0.00e+00	3.17e-01	1.00e+00	Retreg2
4	chr17	56581483	57955699	1	1	9.35e-11	1.86e-01	1.00e+00	LOC108348573
5	chr20	43987022	45386226	1	1	8.06e-08	2.48e-01	1.04e-13	LOC134483824

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	866.87	1	1	20	0	1.00e+00	Retreg2
BMI without tail	57243.66	1	1	20	0	1.00e+00	Retreg2
Body weight	3.66	1	0	0	0	1.00e+00	Retreg2
Epididymis fat weight	36276.19	1	1	20	0	1.00e+00	Retreg2
Glucose	273.37	2	1	20	0	1.00e+00	LOC134486553 Retreg2
Heart weight	3065.65	1	1	20	0	1.00e+00	Retreg2
Left kidney weight	27523.9	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Right kidney weight	40399.64	1	1	20	0	1.00e+00	Retreg2
Tail length	14460.94	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Length with tail	743.1	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Length without tail	47233.74	1	1	20	0	1.00e+00	Retreg2
Liver weight, left	3487.23	1	1	20	0	1.00e+00	Retreg2
Liver weight, right	23.83	3	2	40	0	1.00e+00	Clec3b LOC134483824 Retreg2
Parametrial fat weight	95.21	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Retroperitoneal fat weight	3938.69	1	1	20	0	1.00e+00	Retreg2
Intraocular pressure	10386.52	1	1	20	0	1.00e+00	Retreg2
Extensor digitorum longus weight	1077.67	1	1	20	0	1.00e+00	Retreg2
Soleus weight	20.71	1	1	20	0	1.00e+00	Retreg2
Tibialis anterior weight	1158.38	1	1	20	0	1.00e+00	Retreg2
Tibia length	385.95	2	1	20	0	1.00e+00	Clec3b Retreg2
Number of licking bursts	33715.41	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Food consumed during 24 hour testing period	35509.41	1	1	20	0	1.00e+00	Retreg2
Times rat made contact with spout	42.42	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Mean time between licks in bursts	111630.35	1	1	20	0	1.00e+00	Retreg2
Mean num. licks in bursts	28377.53	2	1	20	0	1.00e+00	Clec3b Retreg2
Std. dev. time between licks in bursts	9921.94	3	1	20	0	1.00e+00	Clec3b LOC134486553 Retreg2
Water consumed over 24 hours	34168.6	1	1	20	0	1.00e+00	Retreg2
Patch foraging indifference point 0 sec	39171.5	1	1	20	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	50128.13	1	1	20	0	1.00e+00	Retreg2
Indifference point function ln k	55646.82	1	1	20	0	1.00e+00	Retreg2
Indifference point function log k	55646.82	1	1	20	0	1.00e+00	Retreg2
Patch foraging total patch changes 0 sec	41947.04	1	1	20	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	1154.32	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Patch foraging total patch changes 18 sec	40454.12	1	1	20	0	1.00e+00	Retreg2
Patch foraging total patch changes 24 sec	37402.79	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Patch foraging total patch changes 6 sec	7787.09	1	1	20	0	1.00e+00	Retreg2
Patch foraging time to switch 0 sec	66489.31	1	1	20	0	1.00e+00	Retreg2
Patch foraging water rate 0 sec	60426.37	1	1	20	0	1.00e+00	Retreg2
Patch foraging water rate 12 sec	70639.93	1	1	20	0	1.00e+00	Retreg2
Patch foraging water rate 18 sec	33728.57	1	1	20	0	1.00e+00	Retreg2
Patch foraging water rate 24 sec	1033.47	1	1	20	0	1.00e+00	Retreg2
Patch foraging water rate 6 sec	837.86	1	1	20	0	1.00e+00	Retreg2
Locomotor testing distance	27661.69	1	1	20	0	1.00e+00	Retreg2
Locomotor testing rearing	31700.47	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Light reinforcement 1	66311.75	1	1	20	0	1.00e+00	Retreg2
Light reinforcement 2	36738.3	1	1	20	0	1.00e+00	Retreg2
Reaction time number correct	31738.33	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Reaction time mean minus median	119950.29	1	1	20	0	1.00e+00	Retreg2
Reaction time mean minus median AUC	61996.51	2	1	20	0	1.00e+00	Clec3b Retreg2
Reaction time num false alarms	7684.56	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Reaction time num false alarms AUC	17512.77	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Reaction time trials correct on left	31738.33	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Reaction time trials on left	30444	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Reaction time mean	14867.01	2	1	20	0	1.00e+00	Clec3b Retreg2
Reaction time mean AUC	19387.31	2	1	20	0	1.00e+00	Clec3b Retreg2
Median of all reaction times	3950.93	2	1	20	0	1.00e+00	Clec3b Retreg2
Reaction time omissions	4187.22	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Reaction time false alarm rate	113.33	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Reaction time premature initiation rate	9733.76	1	1	20	0	1.00e+00	Retreg2
Reaction time premature initiations	53743.58	1	1	20	0	1.00e+00	Retreg2
Std. dev. reaction times	30438.3	2	1	20	0	1.00e+00	Clec3b Retreg2
Reaction time trials completed	30444	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Reaction time trials AUC	31067.47	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Social response proportion	8777.03	1	1	20	0	1.00e+00	Retreg2
Social responses	1265.33	1	1	20	0	1.00e+00	Retreg2
Social time	11650.06	1	1	20	0	1.00e+00	Retreg2
Conditioned locomotion	1400.08	1	1	20	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	19128.47	1	1	20	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	18571.31	1	1	20	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	20	0	1.00e+00	Retreg2
Saline control response	3160.68	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	14521.56	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	14361.09	2	1	20	0	1.00e+00	Clec3b Retreg2
Condit. Reinf. active responses	2302.04	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	5453.58	2	1	20	0	1.00e+00	Clec3b Retreg2
Condit. Reinf. lever presses	3863.86	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. lever reinforcers received	469.54	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	2531.81	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	13282.18	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	39811.91	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. index score	12744.53	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	16150.81	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	5331.08	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	4012.39	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	34989.79	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	11800.43	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	1164.95	1	1	20	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	100795.1	1	1	20	0	1.00e+00	Retreg2
Conditioned reinforcement - inactives	64866.71	1	1	20	0	1.00e+00	Retreg2
Conditioned locomotion	5173.6	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Intermittent access intake day 1-15 change	63948.73	2	2	40	0	1.00e+00	LOC108348573 Retreg2
Intermittent access intake escalation	63045.23	2	2	40	0	1.00e+00	LOC108348573 Retreg2
Intermittent access intake escalation 2	18116.37	2	2	40	0	1.00e+00	LOC108348573 Retreg2
Intermitt. access day 1 inactive lever presses	180612.88	1	1	20	0	1.00e+00	Retreg2
Intermitt. access day 15 inactive lever presses	41206.31	3	1	20	0	1.00e+00	LOC108348573 LOC134483824 Retreg2
Intermitt. access escalation Index	93297.07	1	1	20	0	1.00e+00	Retreg2
Intermittent access day 1 total infusions	22042.44	3	1	20	0	1.00e+00	LOC108348573 LOC134486553 Retreg2
Intermittent access day 15 total infusions	24369.24	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Intermittent access terminal intake (last 3 days)	24800.59	1	1	20	0	1.00e+00	Retreg2
Intermittent access total infusions	94.57	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Intermittent access day 1 locomotion	34964.22	1	1	20	0	1.00e+00	Retreg2
Intermittent access day 15 total locomotion	42776.95	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Intermittent access total locomotion	116.36	1	1	20	0	1.00e+00	Retreg2
Intermittent access standard deviation	56983.89	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Cocaine induced anxiety	69097.7	1	1	20	0	1.00e+00	Retreg2
Post-drug Anxiety	4753.56	1	1	20	0	1.00e+00	Retreg2
Baseline Anxiety	16758.06	2	1	20	0	1.00e+00	LOC134486553 Retreg2
Lifetime Intake	832.41	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Incentive Sensitization - Responses	71347.91	1	1	20	0	1.00e+00	Retreg2
Incentive Sensitization - Breakpoint	55273.76	1	1	20	0	1.00e+00	Retreg2
Progressive ratio test 1 active lever presses	10669.02	3	1	20	0	1.00e+00	LOC108348573 LOC134483824 Retreg2
Progressive ratio test 1 breakpoint	10107.44	3	1	20	0	1.00e+00	LOC108348573 LOC134483824 Retreg2
Progressive ratio test 1 inactive lever presses	31105.72	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Progressive ratio test 2 active lever presses	15263.76	1	1	20	0	1.00e+00	Retreg2
Progressive ratio test 2 breakpoint	4274.23	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Progressive ratio test 2 inactive lever presses	72504.33	1	1	20	0	1.00e+00	Retreg2
Total sessions with >9 infusions	986.77	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Short access day 1 total inactive lever presses	19707.17	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Short access day 10 total inactive lever presses	69422.71	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Short access day 1 total infusions	19208.32	2	2	40	0	1.00e+00	LOC134483824 Retreg2
Short access day 10 total infusions	7574.15	3	1	20	0	1.00e+00	LOC108348573 LOC134483824 Retreg2
Short access total infusions	4398.31	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Short access day 1 locomotion	12413.34	2	2	40	0	1.00e+00	LOC134483824 Retreg2
Short access day 10 total locomotion	44090.94	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Short access total locomotion	9342.37	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Compulsive drug intake	9346.23	2	1	20	0	1.00e+00	LOC134483824 Retreg2
One hour access (0.3 mA shock)	1167.89	2	1	20	0	1.00e+00	LOC108348573 Retreg2
One hour access (shock baseline)	27497.31	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Number of responses in last shaping day	13618.48	1	1	20	0	1.00e+00	Retreg2
Context. condit. distance diff. score	212.47	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 1	3523.61	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 1	519.22	2	1	20	0	1.00e+00	Clec3b Retreg2
Locomotion velocity, session 2	1082.17	2	1	20	0	1.00e+00	Clec3b Retreg2
Locomotion distance, session 2	262.21	2	1	20	0	1.00e+00	Clec3b Retreg2
Locomotion velocity, session 3	507.49	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 3	4009.46	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	685.78	2	1	20	0	1.00e+00	Clec3b Retreg2
Stereotopy head waving duration, day 3	1440.36	2	1	20	0	1.00e+00	Clec3b Retreg2
Locomotion velocity, session 7	150.94	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Locomotion distance, session 7	431.85	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Stereotopy head waving bouts, day 7	1265.52	2	1	20	0	1.00e+00	Clec3b Retreg2
Stereotopy head waving duration, day 7	1068.64	2	1	20	0	1.00e+00	Clec3b Retreg2
Locomotion velocity, session 8	409.23	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 8	78.04	2	1	20	0	1.00e+00	Clec3b Retreg2
Degree of sensitization distance	1840.58	2	1	20	0	1.00e+00	Clec3b Retreg2
Degree of sensitization stereotypy	1030.23	2	1	20	0	1.00e+00	Clec3b Retreg2
Condit. Reinf. active minus inactive responses	482.09	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Condit. Reinf. active-inactive response ratio	242.03	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active responses	1386.95	2	1	20	0	1.00e+00	Clec3b Retreg2
Condit. Reinf. inactive responses	2346.27	2	1	20	0	1.00e+00	Clec3b Retreg2
Incentive salience index mean	1184.82	3	1	20	0	1.00e+00	Clec3b LOC134483824 Retreg2
Condit. Reinf. lever presses	1766.97	3	1	20	0	1.00e+00	Clec3b LOC134483824 Retreg2
Time in familiar zone, hab. session 1	5590.83	2	1	20	0	1.00e+00	Clec3b Retreg2
Time in novel zone, hab. session 1	4619.75	2	1	20	0	1.00e+00	Clec3b Retreg2
Total zone transitions, hab. session 1	429.72	1	1	20	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	394.1	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	266.96	1	1	20	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	5880.03	1	1	20	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	6311.49	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	34.93	2	1	20	0	1.00e+00	Clec3b Retreg2
Total locomotion distance, hab. session 2	15.45	2	1	20	0	1.00e+00	Clec3b Retreg2
Locomotion velocity, hab. session 2	24.52	2	1	20	0	1.00e+00	Clec3b Retreg2
Novel to familiar place preference ratio	7674.1	2	1	20	0	1.00e+00	Clec3b Retreg2
Novelty place preference	7469.43	2	1	20	0	1.00e+00	Clec3b Retreg2
Time in novel zone, NPP test	5349.89	2	1	20	0	1.00e+00	Clec3b Retreg2
Total zone transitions, NPP test	973.86	2	1	20	0	1.00e+00	Clec3b Retreg2
Total locomotion distance, NPP test	1687.31	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	479.1	2	1	20	0	1.00e+00	Clec3b Retreg2
Pavlov. Cond. lever latency	254.89	2	1	20	0	1.00e+00	Clec3b Retreg2
Pavlov. Cond. magazine entry latency	7.63	2	0	0	0	1.00e+00	Clec3b LOC134486553
Pavlov. Cond. change in total contacts	531.56	2	1	20	0	1.00e+00	Clec3b Retreg2
Pavlov. Cond. index score	203.78	2	2	40	0	1.00e+00	Clec3b Retreg2
Pavlov. Cond. latency score	211.57	2	1	20	0	1.00e+00	Clec3b Retreg2
Pavlov. Cond. lever contacts	356.79	2	2	40	0	1.00e+00	Clec3b Retreg2
Pavlov. Cond. magazine entry number	250.13	2	1	20	0	1.00e+00	Clec3b Retreg2
Pavlov. Cond. intertrial magazine entries	123.55	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	223.48	2	2	40	0	1.00e+00	Clec3b Retreg2
Pavlov. Cond. response bias	305.35	2	2	40	0	1.00e+00	Clec3b Retreg2
Bone: apparent density	5461.77	1	1	20	0	1.00e+00	Retreg2
Bone surface	6197.68	1	1	20	0	1.00e+00	Retreg2
Bone volume	8624.75	1	1	20	0	1.00e+00	Retreg2
Bone: connectivity density	1667.52	1	1	20	0	1.00e+00	Retreg2
Bone: cortical apparent density	4020.48	3	2	40	0	1.00e+00	Clec3b LOC134483824 Retreg2
Bone: cortical area	2295.19	2	1	20	0	1.00e+00	Clec3b Retreg2
Bone: cortical porosity	152.45	3	1	20	0	1.00e+00	Clec3b LOC134483824 Retreg2
Bone: cortical porosity	375.8	3	1	20	0	1.00e+00	Clec3b LOC134483824 Retreg2
Bone: cortical thickness	133.44	3	2	40	0	1.00e+00	Clec3b LOC134483824 Retreg2
Bone: cortical thickness	2918.77	1	1	20	0	1.00e+00	Retreg2
Bone: cortical tissue density	4346.62	3	2	40	0	1.00e+00	Clec3b LOC134483824 Retreg2
Bone: elastic displacement	3819.66	2	2	40	0	1.00e+00	Clec3b Retreg2
Bone: elastic work	191.83	2	2	40	0	1.00e+00	Clec3b Retreg2
Bone: endosteal estimation	4459	2	1	20	0	1.00e+00	Clec3b Retreg2
Bone: endosteal perimeter	5933.74	2	1	20	0	1.00e+00	Clec3b Retreg2
Bone: final force	804.26	2	1	20	0	1.00e+00	Clec3b Retreg2
Bone: final moment	115.83	2	1	20	0	1.00e+00	Clec3b Retreg2
Bone: marrow area	4717.39	2	1	20	0	1.00e+00	Clec3b Retreg2
Bone: maximum diameter	6068.73	1	1	20	0	1.00e+00	Retreg2
Bone: maximum force	8697.09	1	1	20	0	1.00e+00	Retreg2
Bone: maximum moment	2997.14	2	1	20	0	1.00e+00	Clec3b Retreg2
Bone: minimum diameter	2053.27	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Bone: periosteal estimation	9791.57	1	1	20	0	1.00e+00	Retreg2
Bone: periosteal perimeter	5702.1	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Bone: post-yield work	6844.24	2	1	20	0	1.00e+00	Clec3b Retreg2
Bone: stiffness	9032.86	1	1	20	0	1.00e+00	Retreg2
Bone: tissue strength	2995.95	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular number	10739.78	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular spacing	7952.12	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular thickness	8476.26	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular tissue density	14554.51	1	1	20	0	1.00e+00	Retreg2
Distance traveled before self-admin	50534.09	1	1	20	0	1.00e+00	Retreg2
Distance traveled after self-admin	16237.59	2	1	20	0	1.00e+00	LOC134486553 Retreg2
Delta time in closed arm before/after self-admin	126.15	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Delta time in open arm before/after self-admin	15131.21	1	1	20	0	1.00e+00	Retreg2
Diff in mean of infusions in LGA sessions	18327.77	2	1	20	0	1.00e+00	LOC134486553 Retreg2
Extinction: sum of active levers before priming	5685.67	5	1	20	1	1.66e-07	Clec3b LOC108348573 LOC134483824 LOC134486553 Retreg2
Active lever presses in extinction session 6	202.19	4	2	40	-0.95	4.93e-02	LOC108348573 LOC134483824 LOC134486553 Retreg2
Delta distance traveled before/after self-admin	2940.47	1	1	20	0	1.00e+00	Retreg2
Delta ambulatory time before/after self-admin	30849.75	1	1	20	0	1.00e+00	Retreg2
Time in closed arm before self-admin	13437.5	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Time in closed arm after self-admin	4591.18	1	1	20	0	1.00e+00	Retreg2
Time in open arm before self-admin	8746.25	1	1	20	0	1.00e+00	Retreg2
Time in open arm after self-admin	242.31	2	1	20	0	1.00e+00	LOC134486553 Retreg2
Sum of active levers in priming session hrs 5-6	256.56	4	2	40	1	4.83e-03	Clec3b LOC108348573 LOC134486553 Retreg2
Time to tail flick, vehicle, before self-admin	6687.56	2	1	20	0	1.00e+00	Clec3b Retreg2
Time to tail flick, vehicle, after self-admin	21076.39	2	1	20	0	1.00e+00	LOC134486553 Retreg2
Time to tail flick, test, before self-admin	4073.4	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Time to tail flick, test, after self-admin	480.11	3	1	20	0	1.00e+00	LOC108348573 LOC134486553 Retreg2
Delta time to tail flick, vehicle, before/after SA	4909.3	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Delta time to tail flick, test, before/after SA	7856.05	2	2	40	0	1.00e+00	LOC134486553 Retreg2
Ambulatory time before self-admin	39444.81	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Ambulatory time after self-admin	8885.03	3	2	40	0	1.00e+00	LOC108348573 LOC134486553 Retreg2
Total heroin consumption	58.89	5	1	20	0.91	3.33e-02	Clec3b LOC108348573 LOC134483824 LOC134486553 Retreg2
Area under the delay curve	12407.64	2	2	40	0	1.00e+00	LOC108348573 Retreg2
Delay disc. indifference point, 0s delay	726.01	3	1	20	0	1.00e+00	LOC108348573 LOC134483824 Retreg2
Delay disc. indifference point, 16s delay	10984.19	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Delay disc. indifference point, 2s delay	83.27	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Delay disc. indifference point, 24s delay	10825.43	3	2	40	0	1.00e+00	Clec3b LOC108348573 Retreg2
Delay disc. indifference point, 4s delay	214.7	3	1	20	0	1.00e+00	LOC108348573 LOC134486553 Retreg2
Delay disc. indifference point, 8s delay	16686.05	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Delay discount exponential model param	8473.8	2	2	40	0	1.00e+00	LOC108348573 Retreg2
Delay discount hyperbolic model param	6149.06	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Fecal boli incidents, locomotor time 1	30604.78	2	1	20	0	1.00e+00	LOC134486553 Retreg2
Change in fecal boli incidents, locomotor task	2839.25	2	1	20	0	1.00e+00	LOC134486553 Retreg2
Time >=10cm from walls, locomotor time 1	13009.3	1	1	20	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 1	10785.17	1	1	20	0	1.00e+00	Retreg2
Total resting periods, locomotor time 1	2793.59	1	1	20	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	22349.64	1	1	20	0	1.00e+00	Retreg2
Distance moved, locomotor task time 1	68821.85	1	1	20	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 1	142354.07	1	1	20	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	71159.6	1	1	20	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 2	82029.05	1	1	20	0	1.00e+00	Retreg2
Total resting periods, locomotor time 2	99042.67	1	1	20	0	1.00e+00	Retreg2
Rest time, locomotor task time 2	25503.09	1	1	20	0	1.00e+00	Retreg2
Distance moved, locomotor task time 2	8477.87	1	1	20	0	1.00e+00	Retreg2
Vertical activity count, locomotor time 2	53555.35	1	1	20	0	1.00e+00	Retreg2
Weight adjusted by age	35393.37	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Seeking ratio, delayed vs. immediate footshock	13445.31	1	1	20	0	1.00e+00	Retreg2
Locomotion in novel chamber	1955.3	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Locomotion in novel chamber post-restriction	32714.78	2	1	20	0	1.00e+00	LOC134486553 Retreg2
Progressive ratio	22633.48	3	1	20	0	1.00e+00	LOC108348573 LOC134483824 Retreg2
Food seeking constrained by brief footshock	630.39	3	1	20	0	1.00e+00	Clec3b LOC134486553 Retreg2
Seeking ratio, punishment vs. effort	20644.58	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Run reversals in cocaine runway, females	4716.05	2	1	20	0	1.00e+00	LOC108348573 Retreg2
Run reversals in cocaine runway, males	7664.74	1	1	20	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway	16290.75	1	1	20	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, F	7166.92	1	1	20	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	1716.51	1	1	20	0	1.00e+00	Retreg2
Cd content in liver	8.89	1	0	0	0	1.00e+00	LOC134483824
Co content in liver	573.41	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Cu content in liver	25.23	2	1	20	0	1.00e+00	Clec3b Retreg2
Fe content in liver	675.94	2	1	20	0	1.00e+00	LOC134483824 Retreg2
K content in liver	1519.62	1	1	20	0	1.00e+00	Retreg2
Mg content in liver	6026.97	1	1	20	0	1.00e+00	Retreg2
Mn content in liver	1009.39	1	1	20	0	1.00e+00	Retreg2
Na content in liver	4018.36	1	1	20	0	1.00e+00	Retreg2
Rb content in liver	47.89	2	1	20	0	1.00e+00	Clec3b Retreg2
Sr content in liver	8.05	1	0	0	0	1.00e+00	LOC134483824
Zn content in liver	1877.44	2	1	20	0	1.00e+00	LOC134483824 Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	0.99
Adipose	alternative TSS	0	0	0.97
Adipose	gene expression	2	0	1.04
Adipose	isoform ratio	0	0	0.98
Adipose	intron excision ratio	0	0	0.96
Adipose	mRNA stability	0	0	1.02
BLA	alternative polyA	0	0	1.01
BLA	alternative TSS	0	0	1.08
BLA	gene expression	0	0	1.04
BLA	isoform ratio	0	0	1.05
BLA	intron excision ratio	0	0	0.97
BLA	mRNA stability	0	0	1.01
Brain	alternative polyA	0	0	1
Brain	alternative TSS	0	0	1.06
Brain	gene expression	0	0	1.06
Brain	isoform ratio	0	0	1.03
Brain	intron excision ratio	0	0	1
Brain	mRNA stability	0	0	1.05
Eye	alternative polyA	0	0	1.02
Eye	alternative TSS	0	0	1.03
Eye	gene expression	0	0	1.04
Eye	isoform ratio	0	0	1.04
Eye	intron excision ratio	0	0	1.01
Eye	mRNA stability	0	0	0.98
IC	alternative polyA	0	0	1.01
IC	alternative TSS	0	0	1.01
IC	gene expression	1	0	1.05
IC	isoform ratio	0	0	1
IC	intron excision ratio	0	0	0.96
IC	mRNA stability	0	0	0.99
IL	alternative polyA	0	0	0.97
IL	alternative TSS	0	0	0.99
IL	gene expression	0	0	1.03
IL	isoform ratio	0	0	1.01
IL	intron excision ratio	0	0	0.91
IL	mRNA stability	0	0	1.04
LHb	alternative polyA	0	0	1.02
LHb	alternative TSS	0	0	0.99
LHb	gene expression	0	0	1.05
LHb	isoform ratio	0	0	1.01
LHb	intron excision ratio	0	0	0.99
LHb	mRNA stability	0	0	1.07
Liver	alternative polyA	0	0	1.1
Liver	alternative TSS	0	0	0.99
Liver	gene expression	1	0	1.03
Liver	isoform ratio	0	0	1.03
Liver	intron excision ratio	0	0	0.95
Liver	mRNA stability	0	0	1.01
NAcc	alternative polyA	1	0	13.86
NAcc	alternative TSS	0	0	1.09
NAcc	gene expression	0	0	1.06
NAcc	isoform ratio	0	0	1.06
NAcc	intron excision ratio	0	0	1.02
NAcc	mRNA stability	0	0	1.04
OFC	alternative polyA	0	0	1.01
OFC	alternative TSS	0	0	1
OFC	gene expression	0	0	1.06
OFC	isoform ratio	0	0	1.04
OFC	intron excision ratio	0	0	0.95
OFC	mRNA stability	0	0	1.02
PL	alternative polyA	0	0	1.06
PL	alternative TSS	0	0	1.09
PL	gene expression	0	0	1.05
PL	isoform ratio	0	0	1.05
PL	intron excision ratio	0	0	1.01
PL	mRNA stability	0	0	1.06
pVTA	alternative polyA	0	0	1
pVTA	alternative TSS	0	0	1.06
pVTA	gene expression	0	0	1.04
pVTA	isoform ratio	0	0	1.02
pVTA	intron excision ratio	0	0	1
pVTA	mRNA stability	0	0	1.01
RMTg	alternative polyA	0	0	1.04
RMTg	alternative TSS	0	0	0.95
RMTg	gene expression	0	0	1.01
RMTg	isoform ratio	0	0	0.98
RMTg	intron excision ratio	0	0	0.89
RMTg	mRNA stability	0	0	1.03