Hub : Genes

LOC120097346

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression LOC120097346 0.09 0.05 3.9e-09 0.07 0.07 0.07 0.07 1.5e-08 7.6e-08 2.9e-08 2.8e-08
2 IC gene expression LOC120097346 0.19 0.1 1.9e-05 0.1 0.11 0.1 0.1 8.7e-05 2.5e-05 4.4e-05 3.6e-05
3 pVTA gene expression LOC120097346 0.03 0.02 5.9e-03 0.02 0.02 0.02 0.01 1.5e-02 1.0e-02 1.5e-02 3.6e-02
4 Brain gene expression LOC120097346 0.15 0.1 9.1e-06 0.02 0.04 0.05 0.04 3.3e-03 1.2e-04 8.3e-06 9.5e-05
5 PL intron excision ratio chr1_164859872_164866553 0.08 0.05 1.2e-07 0.06 0.07 0.07 0.07 3.1e-07 5.3e-08 2.0e-08 3.5e-08
6 Brain alternative polyA XR_005494596.2 0.03 0.02 2.6e-03 0.01 0.01 0.01 0.01 3.0e-02 1.4e-02 4.5e-02 3.7e-02
7 Liver intron excision ratio chr1_164859872_164866553 0.07 0.04 1.3e-06 0.04 0.04 0.04 0.04 3.8e-05 1.4e-05 3.3e-05 2.3e-05
8 NAcc gene expression LOC120097346 0.08 0.04 5.0e-13 0.09 0.07 0.08 0.08 2.8e-13 1.7e-11 1.2e-11 5.0e-12
9 PL gene expression LOC120097346 0.24 0.11 1.7e-13 0.13 0.12 0.1 0.12 7.1e-14 3.8e-13 1.8e-11 1.7e-13
10 PL intron excision ratio chr1_164859872_164866530 0.06 0.05 2.0e-03 0.04 0.03 0.03 0.04 6.2e-05 5.2e-04 1.7e-04 8.5e-05
11 Liver intron excision ratio chr1_164859872_164866530 0.07 0.04 1.7e-06 0.05 0.04 0.04 0.04 7.6e-06 1.6e-05 3.1e-05 2.1e-05
12 Liver isoform ratio XR_010060720.1 0.03 0.02 7.0e-03 0.01 0.01 0 0.01 2.3e-02 1.7e-02 9.0e-02 6.0e-02
13 IL gene expression LOC120097346 0.57 0.21 5.3e-04 0.12 0.03 0.05 0.09 9.9e-04 7.4e-02 2.1e-02 3.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.10.20.90.6-0.1-0.2-0.30.5-0.2-0.1-0.6-0.5-0.60.31.00.0
Area under the delay curve0.30.41.40.7-0.3-0.60.8-0.60.50.70.70.60.41.2-0.10.6
BMI with tail0.51.83.50.3-1.5-0.31.7-1.81.50.51.41.51.7-1.9-1.20.0
BMI without tail0.21.26.2-1.3-0.50.8-0.5-0.40.6-0.20.50.60.4-2.5-2.20.0
Body weight0.52.38.0-1.4-1.0-0.20.7-1.81.51.11.92.01.9-0.8-2.80.0
Weight adjusted by age0.00.10.8-0.40.00.3-0.30.00.10.00.20.20.0-0.4-0.90.0
Bone surface0.40.91.9-1.11.21.0-1.41.1-1.0-0.6-1.0-1.0-1.0-0.1-0.60.0
Bone volume0.10.30.6-0.80.80.5-0.70.5-0.6-0.3-0.5-0.4-0.50.2-0.50.0
Breakpoint value in progressive ratio session0.20.41.50.5-0.7-0.80.9-0.50.40.30.30.10.50.21.20.0
Number of licking bursts1.44.48.32.1-2.9-2.62.1-2.12.62.42.02.01.91.80.70.0
Context. condit. distance diff. score2.83.45.3-1.72.22.2-2.32.1-2.1-2.1-1.6-1.7-1.8-2.1-0.40.0
Locomotion velocity, session 10.40.52.10.8-0.10.1-0.10.7-0.4-0.7-0.7-0.8-0.6-0.81.50.0
Locomotion distance, session 11.51.93.3-0.81.21.5-1.31.6-1.5-1.7-1.5-1.5-1.6-1.80.40.0
Locomotion velocity, session 20.30.41.5-0.50.20.6-0.60.8-0.3-0.7-0.6-0.6-0.6-1.2-0.10.0
Locomotion distance, session 20.50.72.7-0.70.71.0-0.40.9-0.8-1.1-0.7-0.7-0.6-1.70.00.0
Locomotion velocity, session 31.01.22.1-0.91.31.1-1.21.1-1.4-1.2-1.1-1.2-1.4-0.80.20.0
Locomotion distance, session 32.32.66.3-0.71.71.5-1.92.1-1.8-1.7-1.7-1.8-2.5-1.10.60.0
Stereotopy head waving bouts, day 30.80.91.9-0.1-0.8-0.90.9-1.21.11.11.11.11.40.9-0.70.0
Stereotopy head waving duration, day 30.20.20.3-0.50.50.5-0.40.4-0.5-0.5-0.5-0.5-0.3-0.6-0.00.0
Locomotion velocity, session 70.20.20.60.6-0.3-0.1-0.30.5-0.0-0.3-0.3-0.2-0.4-0.60.80.0
Locomotion distance, session 70.30.30.70.7-0.6-0.70.7-0.50.60.60.80.80.40.50.10.0
Stereotopy head waving bouts, day 74.75.49.6-2.32.52.5-3.12.7-2.6-2.3-2.7-2.8-2.3-1.7-0.40.0
Stereotopy head waving duration, day 74.05.07.9-2.42.52.5-2.82.5-2.4-2.3-2.5-2.6-2.1-1.8-0.60.0
Locomotion velocity, session 81.11.42.3-1.51.31.3-1.51.4-1.3-1.2-1.0-1.1-1.2-1.1-0.50.0
Locomotion distance, session 82.43.56.6-2.12.12.3-1.92.0-2.1-2.2-1.6-1.6-1.6-2.6-0.60.0
Degree of sensitization distance3.03.37.20.1-1.6-1.51.8-2.22.02.02.32.42.71.2-1.50.0
Degree of sensitization stereotypy7.07.812.6-2.83.33.2-3.53.1-3.2-2.9-3.0-3.1-2.7-2.2-0.70.0
Conditioned locomotion0.91.03.10.2-0.1-0.81.8-1.60.30.71.11.31.51.20.20.0
Cocaine response after cond. corrected1.31.93.61.3-1.9-1.61.5-1.61.81.51.41.41.31.00.10.0
Cocaine response after cond. not corrected0.20.31.11.0-1.0-0.60.6-0.50.80.50.20.30.30.10.40.0
Cocaine response before conditioning3.44.16.7-0.82.02.1-2.22.3-2.3-2.4-2.6-2.5-2.2-2.10.60.0
Saline control response1.01.44.8-2.21.61.3-1.50.9-1.1-0.6-0.8-0.8-0.6-0.2-1.70.0
Bone: connectivity density0.81.22.80.60.40.6-1.21.6-0.9-1.0-1.4-1.5-1.7-0.81.30.0
Bone: cortical apparent density2.13.35.01.4-2.0-2.12.1-2.22.01.92.12.12.11.40.20.0
Bone: cortical area0.10.20.9-0.90.10.10.2-0.50.20.20.20.30.5-0.0-0.90.0
Bone: cortical porosity0.30.41.3-0.11.10.50.10.3-1.0-0.6-0.6-0.6-0.50.40.50.0
Bone: cortical porosity0.60.61.8-0.41.30.8-0.40.6-1.2-0.8-1.0-1.0-0.70.30.40.0
Bone: cortical thickness0.20.30.80.6-0.8-0.70.9-0.80.60.30.30.50.5-0.20.70.0
Bone: cortical thickness0.10.10.2-0.30.30.10.4-0.4-0.2-0.10.10.20.4-0.0-0.10.0
Bone: cortical tissue density2.03.24.81.5-2.0-2.02.1-2.22.01.92.12.12.01.40.30.0
Condit. Reinf. active minus inactive responses0.20.31.4-0.80.20.0-0.2-0.50.20.50.30.40.60.5-1.20.0
Condit. Reinf. active-inactive response ratio0.30.32.1-1.00.50.2-0.5-0.1-0.00.40.10.20.20.8-1.40.0
Condit. Reinf. active responses0.30.40.9-0.5-0.1-0.40.6-0.90.40.70.60.60.90.9-0.80.0
Condit. Reinf. inactive responses0.20.31.30.1-0.3-0.51.1-0.70.30.30.60.50.70.30.30.0
Incentive salience index mean0.20.21.0-0.80.20.00.1-0.40.20.40.20.30.70.6-1.00.0
Condit. Reinf. lever presses0.10.20.6-0.70.30.4-0.30.5-0.3-0.3-0.8-0.6-0.0-0.1-0.30.0
Condit. Reinf. active minus inactive responses3.55.513.9-3.72.82.9-2.92.2-2.2-1.8-1.7-1.8-1.5-1.7-2.80.0
Condit. Reinf. active-inactive response ratio1.01.73.2-1.51.31.5-1.81.5-1.2-1.1-1.3-1.3-1.2-1.1-0.90.0
Condit. Reinf. active responses4.66.620.4-4.53.23.2-3.02.1-2.2-1.8-1.7-1.6-1.4-1.7-3.70.0
Condit. Reinf. inactive responses1.72.611.1-3.32.11.9-1.30.7-1.2-0.8-0.6-0.5-0.3-0.7-3.00.0
Condit. Reinf. lever presses9.814.231.3-5.64.84.9-4.23.6-3.9-3.5-3.0-2.9-2.7-3.3-3.70.0
Condit. Reinf. lever reinforcers received5.78.023.3-4.83.53.5-3.32.5-2.6-2.1-2.1-2.0-1.7-1.8-3.70.0
Conditioned reinforcement - actives0.21.02.5-0.31.61.2-0.50.9-1.5-1.3-0.9-1.0-1.2-0.50.20.0
Conditioned reinforcement - inactives0.30.92.11.0-0.4-0.91.4-1.10.50.80.90.81.21.50.30.0
Conditioned locomotion2.43.55.8-0.52.32.0-1.42.2-2.4-2.3-2.1-2.2-2.4-1.50.80.0
Patch foraging indifference point 0 sec0.92.65.4-1.92.32.2-1.51.4-2.0-1.8-1.1-1.1-1.7-1.5-1.10.0
Patch foraging indifference point AUC0.10.31.4-0.7-0.3-0.00.4-0.50.50.50.40.40.6-0.1-1.20.0
Delay disc. indifference point, 0s delay0.50.52.0-1.40.90.9-0.70.5-0.7-0.5-0.3-0.3-0.4-0.5-1.0-0.1
Delay disc. indifference point, 16s delay0.50.82.80.8-0.2-0.80.8-0.90.50.81.01.00.71.70.21.0
Delay disc. indifference point, 2s delay0.30.31.5-1.10.60.5-0.50.3-0.20.0-0.1-0.2-0.30.3-1.2-0.1
Delay disc. indifference point, 24s delay1.72.84.51.6-1.2-1.62.1-2.01.31.41.81.71.71.90.62.1
Delay disc. indifference point, 4s delay0.50.53.2-1.70.40.5-0.4-0.10.00.20.30.30.30.2-1.80.5
Delay disc. indifference point, 8s delay0.20.30.90.9-0.2-0.40.8-0.30.30.40.60.50.30.80.10.3
Indifference point function ln k0.61.83.4-0.41.71.3-1.41.6-1.9-1.6-1.5-1.4-1.5-0.70.90.0
Indifference point function log k0.61.83.4-0.41.71.3-1.41.6-1.9-1.6-1.5-1.4-1.5-0.70.90.0
Patch foraging total patch changes 0 sec0.72.24.1-1.72.02.0-1.41.3-1.7-1.6-0.9-1.0-1.5-1.6-1.00.0
Patch foraging total patch changes 12 sec0.40.53.2-1.30.40.50.1-0.50.10.20.70.60.2-0.2-1.80.0
Patch foraging total patch changes 18 sec0.40.92.0-1.41.41.4-0.70.6-0.9-0.8-0.7-0.6-0.6-0.8-1.40.0
Patch foraging total patch changes 24 sec0.10.43.1-1.10.50.6-0.3-0.20.00.10.50.50.1-0.3-1.80.0
Patch foraging total patch changes 6 sec0.20.30.9-0.70.80.8-0.40.3-0.6-0.7-0.2-0.2-0.5-1.0-0.50.0
Patch foraging time to switch 0 sec0.83.16.12.5-2.2-2.32.0-1.61.81.71.21.21.41.91.70.0
Patch foraging water rate 0 sec0.72.64.9-1.92.22.2-1.91.5-1.9-1.7-1.2-1.2-1.3-1.6-1.10.0
Patch foraging water rate 12 sec0.62.67.4-1.11.72.1-1.51.4-1.8-2.2-1.3-1.3-1.5-2.7-0.20.0
Patch foraging water rate 18 sec0.92.14.7-1.81.31.8-2.01.5-1.2-1.4-0.9-0.9-1.2-2.2-1.20.0
Patch foraging water rate 24 sec0.91.22.5-0.31.41.3-0.80.8-1.5-1.6-1.2-1.2-0.8-1.50.60.0
Patch foraging water rate 6 sec0.91.42.8-0.81.31.5-1.21.3-1.4-1.5-0.9-0.9-1.1-1.7-0.00.0
Seeking ratio, delayed vs. immediate footshock0.40.52.51.4-0.8-0.90.7-0.10.50.30.1-0.00.00.61.60.0
Distance traveled before self-admin0.30.71.70.5-1.3-1.00.8-0.91.10.71.11.10.9-0.30.40.0
Distance traveled after self-admin0.30.62.60.6-0.10.1-0.80.7-0.5-0.8-0.4-0.5-0.7-1.21.60.0
Extensor digitorum longus weight0.31.12.10.4-1.3-0.80.9-1.21.51.21.31.11.30.3-0.90.0
Bone: elastic displacement0.60.73.61.7-1.2-1.00.4-0.00.60.2-0.3-0.3-0.10.11.90.0
Bone: elastic work0.81.15.72.2-1.2-0.90.50.10.4-0.1-0.6-0.5-0.3-0.22.40.0
Bone: endosteal estimation0.41.05.5-1.91.01.0-1.10.3-0.4-0.0-0.2-0.10.10.2-2.40.0
Bone: endosteal perimeter0.61.55.7-2.41.31.4-1.50.8-0.7-0.4-0.6-0.6-0.4-0.3-2.40.0
Epididymis fat weight0.31.63.11.4-1.5-1.31.8-1.51.41.11.31.41.20.30.30.0
Delta time in closed arm before/after self-admin3.53.35.41.4-2.0-1.82.0-2.32.22.02.32.22.01.3-0.60.0
Delta time in open arm before/after self-admin1.92.24.8-1.81.91.8-2.21.7-1.5-1.2-1.4-1.3-1.4-0.5-1.30.0
Diff in mean of infusions in LGA sessions1.52.87.20.9-1.9-2.31.8-1.51.82.11.31.21.42.70.90.0
Delay discount exponential model param0.30.41.1-0.70.40.5-0.80.6-0.5-0.6-0.7-0.6-0.4-1.00.1-0.7
Extinction: sum of active levers before priming0.00.00.2-0.50.10.1-0.2-0.1-0.00.1-0.1-0.20.20.1-0.40.0
Active lever presses in extinction session 62.62.64.8-0.61.91.5-0.91.9-2.2-2.1-1.7-1.8-1.8-1.51.40.0
Bone: final force0.71.12.70.3-0.4-1.01.5-1.40.71.11.01.21.31.6-0.10.0
Bone: final moment0.40.71.90.1-0.2-0.71.2-1.20.50.90.80.91.11.4-0.30.0
Food consumed during 24 hour testing period2.65.37.8-2.12.62.6-2.62.8-2.6-2.5-2.6-2.6-2.5-1.9-0.30.0
Glucose0.20.30.9-0.1-0.10.3-0.80.6-0.2-0.4-0.9-0.9-0.5-0.70.20.0
Heart weight0.61.01.9-1.11.41.1-1.10.9-1.2-0.9-1.1-1.0-1.2-0.4-0.50.0
Delay discount hyperbolic model param0.30.41.1-0.50.40.5-0.70.5-0.5-0.7-0.7-0.6-0.4-1.00.3-0.7
Intermittent access intake day 1-15 change0.31.94.2-0.50.91.4-1.61.7-1.3-1.7-1.4-1.5-1.6-2.10.50.0
Intermittent access intake escalation0.52.64.4-0.81.11.7-2.02.0-1.5-1.9-1.7-1.8-2.0-2.10.50.0
Intermittent access intake escalation 20.30.51.0-0.30.70.9-0.80.9-0.8-0.9-0.5-0.6-0.9-1.0-0.10.0
Intermitt. access day 1 inactive lever presses0.22.43.91.3-1.5-1.71.8-1.61.61.71.71.71.82.00.30.0
Intermitt. access day 15 inactive lever presses0.00.31.21.0-0.3-0.60.5-0.10.10.10.10.00.30.41.10.0
Intermitt. access escalation Index0.00.00.3-0.10.10.1-0.60.3-0.1-0.00.00.0-0.10.1-0.20.0
Intermittent access day 1 total infusions0.51.43.6-1.41.91.4-0.91.1-1.6-1.2-1.2-1.2-0.8-0.4-0.50.0
Intermittent access day 15 total infusions0.92.13.7-1.21.91.8-1.31.5-1.9-1.7-1.6-1.6-1.4-1.1-0.00.0
Intermittent access terminal intake (last 3 days)1.01.83.8-1.41.91.7-1.31.4-1.8-1.6-1.2-1.3-1.3-0.9-0.40.0
Intermittent access total infusions1.41.63.3-1.41.81.7-1.11.2-1.6-1.4-1.2-1.3-1.1-0.9-0.70.0
Intermittent access day 1 locomotion0.30.51.2-0.21.10.6-0.50.8-1.0-0.6-1.0-1.0-0.90.50.30.0
Intermittent access day 15 total locomotion0.62.44.3-0.61.61.5-1.01.9-1.8-1.7-2.1-2.1-2.0-1.00.90.0
Intermittent access total locomotion1.21.42.4-0.91.51.3-1.01.4-1.5-1.3-1.5-1.4-1.5-0.60.10.0
Intermittent access standard deviation0.00.20.6-0.6-0.30.10.4-0.30.3-0.00.60.50.3-0.8-0.60.0
Left kidney weight0.10.93.4-0.8-0.60.10.4-1.10.90.51.01.11.3-0.9-1.80.0
Right kidney weight0.21.66.2-0.8-0.5-0.00.6-1.51.10.91.71.81.7-0.5-2.50.0
Cocaine induced anxiety1.02.75.11.8-1.6-2.02.3-1.61.51.61.41.41.52.11.20.0
Post-drug Anxiety1.92.24.61.0-1.5-1.91.7-1.61.51.81.41.41.42.10.50.0
Baseline Anxiety0.40.72.4-1.50.80.7-1.50.6-0.6-0.3-0.5-0.5-0.4-0.3-1.10.0
Tail length0.42.414.8-3.30.50.7-1.70.00.40.80.60.60.40.3-3.80.0
Length with tail0.52.112.0-3.10.40.4-1.2-0.50.40.91.01.00.90.5-3.50.0
Length without tail0.00.20.4-0.6-0.3-0.4-0.3-0.30.40.50.60.60.50.5-0.50.0
Times rat made contact with spout0.30.30.8-0.2-0.8-0.60.1-0.40.90.90.40.50.40.8-0.60.0
Lifetime Intake1.82.24.3-1.62.11.9-1.41.4-1.9-1.7-1.5-1.5-1.3-1.2-0.70.0
Liver weight, left0.81.32.40.3-1.0-0.90.8-1.31.41.41.51.51.31.3-1.10.0
Liver weight, right2.23.97.10.6-2.0-1.81.5-2.52.42.32.72.72.41.5-1.50.0
Locomotor activity0.20.31.0-0.80.80.8-0.40.3-0.7-0.7-0.1-0.1-0.5-1.0-0.30.0
Locomotor testing distance0.51.13.9-2.01.21.4-1.10.6-0.9-0.9-0.2-0.2-0.5-1.3-1.50.0
Locomotor testing rearing0.10.52.9-1.60.30.4-0.4-0.30.10.20.50.40.4-0.3-1.70.0
Locomotion in novel chamber0.40.51.61.20.50.40.80.1-0.7-0.8-0.7-0.7-0.4-0.41.20.0
Locomotion in novel chamber post-restriction1.13.46.0-1.12.02.0-2.12.3-2.1-1.9-2.3-2.4-2.1-1.20.10.0
Fecal boli incidents, locomotor time 10.20.51.60.90.70.11.10.5-0.6-0.2-0.2-0.1-0.31.31.0-0.8
Change in fecal boli incidents, locomotor task0.30.30.50.7-0.7-0.4-0.5-0.70.60.40.50.40.4-0.3-0.20.7
Time >=10cm from walls, locomotor time 10.60.72.6-0.41.61.1-0.60.8-1.3-1.0-0.7-0.7-0.5-0.2-0.2-0.4
Bouts of movement, locomotor time 10.10.21.0-0.30.60.1-0.10.5-0.30.1-0.00.10.11.0-0.3-0.8
Total resting periods, locomotor time 10.20.21.10.20.60.0-0.00.7-0.5-0.1-0.3-0.2-0.10.80.4-1.1
Rest time, locomotor task time 10.30.52.00.80.50.0-0.70.8-0.6-0.3-0.5-0.4-0.40.50.8-1.4
Distance moved, locomotor task time 10.10.41.3-0.8-0.6-0.10.4-0.70.70.40.30.30.6-0.2-0.91.2
Vertical activity count, locomotor time 10.00.31.0-1.0-0.10.00.5-0.50.40.40.20.20.80.4-1.00.8
Time >=10cm from walls, locomotor time 20.20.72.7-1.21.41.0-0.9-0.0-0.8-0.40.20.20.2-0.1-1.60.5
Bouts of movement, locomotor time 20.72.46.1-0.4-0.1-0.51.3-2.00.81.31.81.91.81.6-1.82.5
Total resting periods, locomotor time 20.62.35.5-0.1-0.4-0.81.5-2.01.01.41.81.91.81.7-1.42.4
Rest time, locomotor task time 20.91.52.91.7-1.7-1.71.0-0.71.41.21.21.20.90.91.3-0.2
Distance moved, locomotor task time 21.11.54.7-2.21.61.6-1.20.6-1.2-1.0-0.9-0.9-0.5-1.0-1.6-0.0
Vertical activity count, locomotor time 20.20.42.0-1.20.70.40.2-0.3-0.20.10.10.10.80.6-1.40.6
Light reinforcement 10.52.45.72.3-2.4-1.91.6-1.61.91.31.61.41.20.21.20.0
Light reinforcement 20.40.93.80.6-0.30.4-0.61.0-0.4-1.0-0.9-1.1-1.0-1.91.30.0
Bone: marrow area0.30.85.1-1.70.80.8-0.90.1-0.20.1-0.1-0.00.20.3-2.30.0
Bone: maximum diameter0.61.35.0-2.21.31.3-1.20.4-0.8-0.5-0.7-0.6-0.4-0.6-2.00.0
Bone: maximum force0.10.31.00.2-0.1-0.50.7-0.70.30.60.40.50.61.0-0.00.0
Bone: maximum moment0.00.10.4-0.10.1-0.20.4-0.40.10.30.20.20.30.7-0.20.0
Mean time between licks in bursts0.32.112.6-2.91.31.1-0.2-0.8-0.20.30.90.90.90.0-3.50.0
Mean num. licks in bursts1.43.86.8-2.22.62.4-2.22.1-2.4-2.1-1.9-1.9-1.8-1.5-0.80.0
Cd content in liver0.40.41.2-0.1-0.7-0.70.4-0.50.81.00.60.50.71.1-0.50.0
Co content in liver0.50.63.1-1.50.90.7-0.4-0.2-0.30.00.20.20.40.2-1.80.0
Cu content in liver0.40.53.2-1.00.10.1-0.3-0.30.40.60.50.50.40.5-1.80.0
Fe content in liver0.00.00.00.0-0.0-0.1-0.00.00.00.1-0.10.1-0.20.10.10.0
K content in liver0.70.71.5-0.1-0.7-0.71.1-1.00.90.81.11.01.20.4-0.50.0
Mg content in liver0.10.10.6-0.40.10.3-0.10.2-0.2-0.40.0-0.1-0.0-0.8-0.20.0
Mn content in liver0.50.53.31.5-0.6-0.60.40.10.1-0.1-0.1-0.2-0.2-0.21.80.0
Na content in liver1.61.83.9-1.41.01.3-2.01.8-1.2-1.3-1.4-1.6-1.6-1.3-0.20.0
Rb content in liver0.40.50.9-0.90.80.6-0.90.9-0.7-0.4-0.8-0.8-0.70.3-0.30.0
Se content in liver2.02.46.72.6-2.0-2.11.5-1.11.41.30.60.80.71.52.20.0
Sr content in liver1.41.22.80.00.50.9-1.31.2-0.9-1.3-1.3-1.4-1.3-1.70.70.0
Zn content in liver1.11.33.0-1.71.31.6-1.10.8-1.0-1.1-0.6-0.7-0.5-1.5-1.60.0
Bone: minimum diameter0.61.25.7-1.6-0.2-0.10.1-1.00.81.01.01.01.20.6-2.40.0
Time in familiar zone, hab. session 10.10.10.3-0.4-0.10.1-0.50.20.20.1-0.1-0.1-0.2-0.2-0.60.0
Time in novel zone, hab. session 10.40.40.70.8-0.6-0.70.6-0.80.60.70.60.70.80.70.20.0
Total zone transitions, hab. session 10.91.32.4-0.50.70.8-1.51.4-1.1-1.2-1.5-1.5-1.3-1.10.80.0
Total locomotion distance, hab. session 11.72.45.30.2-1.5-1.41.1-2.01.91.82.02.02.30.9-1.30.0
Locomotion velocity, hab. session 11.41.94.6-0.0-1.3-1.21.3-1.81.51.51.81.82.10.7-1.10.0
Time in familiar zone, hab. session 20.60.62.1-1.21.31.0-0.90.4-0.8-0.5-0.1-0.10.2-0.4-1.50.0
Time in novel zone, hab. session 20.30.31.50.9-0.7-0.30.5-0.00.2-0.2-0.2-0.2-0.4-0.51.20.0
Total zone transitions, hab. session 22.93.75.6-2.01.92.0-2.42.1-2.1-2.1-2.2-2.2-1.8-2.10.00.0
Total locomotion distance, hab. session 21.21.64.1-1.1-0.6-0.50.8-1.71.11.11.71.72.00.0-1.90.0
Locomotion velocity, hab. session 21.41.94.5-1.1-0.8-0.70.9-1.81.31.31.91.92.10.2-2.00.0
Novel to familiar place preference ratio0.50.71.8-0.70.3-0.41.0-1.10.20.71.00.91.01.4-0.60.0
Novelty place preference0.50.61.5-0.80.3-0.40.9-1.10.10.61.00.91.01.2-0.70.0
Time in novel zone, NPP test0.50.61.3-0.90.5-0.20.9-1.1-0.00.50.90.91.01.1-0.80.0
Total zone transitions, NPP test0.91.32.5-0.50.61.0-0.91.4-1.0-1.4-1.5-1.5-1.3-1.60.80.0
Total locomotion distance, NPP test1.31.83.80.2-1.5-1.01.6-1.81.61.21.71.82.0-0.2-0.90.0
Locomotion velocity, NPP test1.52.13.70.5-1.8-1.21.7-1.91.81.31.81.81.9-0.1-0.60.0
Intraocular pressure0.91.43.10.80.60.8-1.01.5-1.1-1.1-1.6-1.8-1.8-0.61.30.0
Delta distance traveled before/after self-admin2.32.54.7-1.12.01.6-2.21.9-2.0-1.6-1.7-1.8-1.8-0.70.20.0
Delta ambulatory time before/after self-admin1.52.64.4-1.12.01.6-2.12.0-2.0-1.7-1.8-1.8-1.8-0.80.40.0
Parametrial fat weight0.30.62.51.4-1.6-0.60.0-0.21.00.2-0.1-0.1-0.3-1.20.80.0
Pavlov. Cond. lever latency0.70.92.11.5-1.3-1.20.8-0.91.00.71.00.90.70.20.90.0
Pavlov. Cond. magazine entry latency2.33.05.3-2.32.02.2-2.21.9-1.7-1.6-1.5-1.4-1.3-1.6-1.60.0
Pavlov. Cond. change in total contacts0.90.92.1-1.51.41.1-1.10.9-1.0-0.6-0.9-0.9-0.70.1-1.00.0
Pavlov. Cond. index score1.82.34.5-2.11.91.9-1.81.6-1.5-1.3-1.5-1.4-1.1-1.0-1.40.0
Pavlov. Cond. latency score1.62.04.2-2.11.81.8-1.51.5-1.5-1.2-1.4-1.3-1.0-0.8-1.40.0
Pavlov. Cond. lever contacts0.80.91.7-1.31.21.2-1.11.0-1.0-0.8-1.0-1.0-0.8-0.5-0.90.0
Pavlov. Cond. magazine entry number2.43.05.42.3-2.1-2.12.1-2.01.81.51.61.51.51.21.50.0
Pavlov. Cond. intertrial magazine entries0.50.51.10.7-0.8-1.00.7-0.80.70.80.60.50.51.10.80.0
Pavlov. Cond. lever-magazine prob. diff.1.72.23.8-1.91.81.8-1.81.7-1.5-1.3-1.6-1.5-1.2-0.9-1.20.0
Pavlov. Cond. response bias1.31.62.6-1.61.41.5-1.61.4-1.2-1.1-1.2-1.2-1.0-1.1-1.00.0
Pavlov. Cond. lever latency12.116.931.35.6-5.0-5.34.6-3.94.34.13.43.33.24.33.40.0
Pavlov. Cond. magazine entry latency3.75.211.3-2.32.42.9-2.32.5-2.4-2.7-2.1-2.0-1.9-3.4-0.70.0
Pavlov. Cond. change in total contacts6.515.829.1-5.44.64.9-4.74.0-4.1-3.9-3.6-3.5-3.2-4.1-2.90.0
Pavlov. Cond. index score8.313.023.6-4.94.34.7-3.93.5-3.8-3.7-3.0-2.9-2.8-4.0-2.70.0
Pavlov. Cond. latency score7.411.920.0-4.54.14.4-3.73.4-3.6-3.6-3.0-2.9-2.7-4.0-2.40.0
Pavlov. Cond. lever contacts10.615.631.5-5.64.95.1-4.43.7-4.1-3.9-3.3-3.2-2.9-3.9-3.40.0
Pavlov. Cond. magazine entry number6.88.913.73.3-3.3-3.73.2-3.33.23.42.82.82.63.71.20.0
Pavlov. Cond. intertrial magazine entries0.30.82.4-0.8-0.3-0.40.3-0.90.81.10.80.71.01.2-1.60.0
Pavlov. Cond. lever-magazine prob. diff.7.711.922.3-4.74.14.5-3.73.3-3.6-3.5-2.8-2.7-2.5-3.9-2.80.0
Pavlov. Cond. response bias12.717.531.5-5.65.05.4-4.74.1-4.4-4.2-3.6-3.5-3.3-4.5-3.20.0
Time in closed arm before self-admin1.62.94.6-1.82.11.8-1.71.8-2.1-2.0-1.8-1.5-1.6-1.80.30.0
Time in closed arm after self-admin0.50.61.50.6-0.6-0.91.2-0.80.50.50.60.70.80.61.00.0
Time in open arm before self-admin2.93.58.83.0-2.6-2.22.2-1.82.21.71.61.31.41.21.30.0
Time in open arm after self-admin0.10.10.60.2-0.10.1-0.70.20.20.20.1-0.1-0.20.2-0.80.0
Bone: periosteal estimation0.30.63.8-1.60.70.8-0.70.0-0.2-0.0-0.2-0.10.1-0.0-1.90.0
Bone: periosteal perimeter0.40.83.3-1.80.81.1-1.00.4-0.4-0.4-0.5-0.4-0.2-0.6-1.80.0
Bone: post-yield work0.00.00.2-0.20.10.1-0.2-0.1-0.00.00.20.20.1-0.2-0.40.0
Progressive ratio test 1 active lever presses0.20.40.90.10.60.4-0.60.9-0.7-0.6-0.9-1.0-0.9-0.10.60.0
Progressive ratio test 1 breakpoint0.20.41.00.10.60.4-0.70.9-0.7-0.6-0.9-1.0-0.9-0.00.60.0
Progressive ratio test 1 inactive lever presses0.10.10.40.60.3-0.0-0.00.2-0.4-0.2-0.5-0.5-0.10.60.60.0
Progressive ratio test 2 active lever presses0.40.51.1-0.80.90.9-0.80.7-0.8-0.6-0.9-1.0-0.6-0.2-0.40.0
Progressive ratio test 2 breakpoint0.50.61.2-0.91.00.9-0.90.8-0.9-0.7-0.9-1.1-0.7-0.2-0.40.0
Progressive ratio test 2 inactive lever presses0.20.51.0-0.30.90.7-0.40.7-1.0-0.9-1.0-1.0-0.5-0.50.40.0
Incentive Sensitization - Responses0.20.41.5-1.20.90.9-0.60.3-0.7-0.5-0.5-0.6-0.2-0.3-0.90.0
Incentive Sensitization - Breakpoint0.20.51.4-1.20.90.9-0.70.4-0.7-0.6-0.6-0.7-0.3-0.5-0.70.0
Sum of active levers in priming session hrs 5-60.20.10.4-0.30.20.2-0.40.4-0.4-0.4-0.5-0.6-0.1-0.60.30.0
Progressive ratio0.61.83.7-0.70.91.2-1.41.9-1.2-1.5-1.7-1.7-1.7-1.50.50.0
Food seeking constrained by brief footshock0.60.72.7-1.10.81.1-1.20.7-0.5-0.5-0.6-0.5-0.3-1.0-1.60.0
Seeking ratio, punishment vs. effort0.40.93.9-0.8-0.2-0.10.2-1.10.70.81.11.11.30.3-2.00.0
Retroperitoneal fat weight2.08.917.21.5-4.1-3.12.8-3.54.13.43.43.43.41.2-1.30.0
Reaction time number correct0.10.31.00.10.70.4-0.00.2-0.9-0.8-0.5-0.5-0.3-0.51.00.0
Reaction time mean minus median0.00.21.3-1.00.60.50.1-0.1-0.2-0.10.20.20.4-0.1-1.10.0
Reaction time mean minus median AUC0.10.31.2-1.01.10.8-0.10.2-0.7-0.5-0.2-0.2-0.1-0.3-0.70.0
Reaction time num false alarms2.74.56.71.7-2.1-2.42.5-2.52.32.32.62.52.32.10.10.0
Reaction time num false alarms AUC1.43.26.01.6-1.6-1.92.4-2.11.81.82.12.12.01.90.30.0
Reaction time trials correct on left0.10.31.00.10.70.4-0.00.2-0.9-0.8-0.5-0.5-0.3-0.51.00.0
Reaction time trials on left0.10.31.00.10.70.40.00.1-0.8-0.8-0.5-0.5-0.3-0.51.00.0
Reaction time mean1.43.25.60.8-1.5-1.82.3-2.21.82.01.92.02.42.1-0.40.0
Reaction time mean AUC1.22.84.90.9-1.4-1.82.2-2.01.71.91.61.72.22.2-0.10.0
Median of all reaction times2.54.06.81.3-1.8-2.22.6-2.32.02.22.02.22.52.4-0.00.0
Reaction time omissions0.30.51.10.1-0.8-0.61.0-1.00.90.80.70.71.00.5-0.40.0
Reaction time false alarm rate2.63.65.51.5-1.9-2.02.4-2.12.12.12.22.22.11.8-0.10.0
Reaction time premature initiation rate0.50.85.9-1.50.40.8-0.6-0.00.20.20.30.30.2-0.5-2.40.0
Reaction time premature initiations0.20.52.3-1.20.81.0-0.50.1-0.4-0.4-0.1-0.1-0.0-0.7-1.50.0
Std. dev. reaction times0.41.32.7-0.6-0.4-0.61.2-1.31.01.31.21.31.61.3-1.70.0
Reaction time trials completed0.10.31.00.10.70.40.00.1-0.8-0.8-0.5-0.5-0.3-0.51.00.0
Reaction time trials AUC0.00.20.60.10.50.30.2-0.1-0.7-0.6-0.3-0.2-0.0-0.40.80.0
Run reversals in cocaine runway, females1.11.23.5-0.6-1.3-0.60.1-1.01.51.21.31.31.3-0.2-1.90.0
Run reversals in cocaine runway, males0.10.20.50.1-0.1-0.20.30.4-0.00.1-0.7-0.7-0.10.70.60.0
Latency to leave start box in cocaine runway1.72.34.81.3-2.2-1.91.1-1.52.11.91.51.51.21.50.10.0
Latency to leave start box in cocaine runway, F2.73.35.70.8-2.3-2.11.5-2.12.42.42.02.01.82.0-0.60.0
Latency to leave start box in cocaine runway, M0.20.21.41.2-0.5-0.3-0.00.20.2-0.1-0.1-0.1-0.6-0.20.90.0
Std. dev. time between licks in bursts0.81.56.6-1.40.0-0.00.9-1.40.81.01.41.51.60.7-2.60.0
Total sessions with >9 infusions2.12.64.3-1.82.12.1-1.71.6-1.8-1.7-1.7-1.6-1.3-1.2-1.00.0
Short access day 1 total inactive lever presses0.10.11.0-0.20.40.10.5-0.1-0.20.1-0.1-0.10.21.0-0.30.0
Short access day 10 total inactive lever presses0.21.42.61.6-1.0-1.31.6-1.21.01.11.01.11.31.50.70.0
Short access day 1 total infusions1.02.16.1-2.52.22.0-1.00.9-1.6-1.2-1.1-1.0-0.7-0.6-1.80.0
Short access day 10 total infusions1.42.33.6-1.71.81.9-1.81.7-1.7-1.5-1.5-1.6-1.4-1.1-0.90.0
Short access total infusions1.92.75.1-1.72.32.1-1.81.7-2.0-1.7-1.6-1.6-1.5-1.1-0.90.0
Short access day 1 locomotion1.83.04.7-1.52.22.0-1.52.1-2.2-1.9-2.0-2.0-1.9-1.00.20.0
Short access day 10 total locomotion0.31.33.3-1.81.21.4-1.01.3-1.2-1.2-1.0-1.0-1.1-1.0-0.60.0
Short access total locomotion1.01.52.7-0.61.21.2-1.21.6-1.4-1.3-1.6-1.6-1.6-0.70.50.0
One hour access (0.3 mA shock)0.81.01.8-0.81.41.4-0.81.1-1.2-1.2-0.8-0.9-1.2-1.0-0.30.0
Compulsive drug intake0.40.54.41.2-0.4-0.60.60.1-0.1-0.2-0.3-0.2-0.20.02.10.0
One hour access (shock baseline)0.72.03.5-1.61.81.9-1.41.3-1.6-1.5-1.0-1.1-1.4-1.5-1.00.0
Social response proportion1.41.84.10.8-1.2-1.12.0-1.91.41.11.81.81.40.4-0.40.0
Social responses2.43.26.40.1-1.3-1.32.5-2.41.81.72.42.42.31.1-1.30.0
Social time1.11.74.21.5-1.6-1.72.0-1.51.21.01.01.00.80.91.40.0
Soleus weight1.33.96.90.3-1.8-1.52.0-2.52.32.22.52.42.61.4-1.80.0
Bone: stiffness1.32.44.90.5-1.1-1.61.9-2.01.41.81.81.91.82.2-0.50.0
Tibialis anterior weight0.20.81.7-0.5-0.4-0.40.7-1.10.80.91.31.21.20.7-1.30.0
Time to tail flick, vehicle, before self-admin0.91.12.9-0.70.71.0-1.71.2-0.9-1.1-1.2-1.3-1.0-1.4-0.10.0
Time to tail flick, vehicle, after self-admin0.61.22.9-1.11.71.4-1.31.1-1.5-1.1-1.2-1.2-1.0-0.0-0.40.0
Time to tail flick, test, before self-admin0.70.82.4-1.30.80.9-1.50.9-0.5-0.2-0.7-0.9-0.9-0.3-1.50.0
Time to tail flick, test, after self-admin0.60.63.0-0.80.20.0-0.4-0.60.40.60.90.90.90.6-1.70.0
Delta time to tail flick, vehicle, before/after SA0.20.20.8-0.20.90.40.40.2-0.6-0.2-0.4-0.2-0.10.9-0.10.0
Delta time to tail flick, test, before/after SA0.91.12.21.1-0.9-1.01.1-1.30.90.71.41.51.50.50.40.0
Tibia length1.12.97.1-1.92.72.0-1.21.9-2.4-1.9-1.8-1.7-1.6-0.7-0.10.0
Ambulatory time before self-admin0.20.61.20.8-1.1-1.00.8-0.80.80.50.90.80.7-0.20.80.0
Ambulatory time after self-admin0.81.22.4-0.10.80.6-1.31.3-1.3-1.4-1.1-1.0-1.3-1.31.60.0
Bone: tissue strength0.70.83.71.0-0.00.1-0.30.8-0.6-0.9-0.9-1.0-0.9-0.91.90.0
Total heroin consumption0.10.20.8-0.80.20.3-0.10.1-0.3-0.4-0.1-0.20.1-0.90.00.0
Bone: trabecular number0.30.52.71.2-0.8-0.6-0.20.50.20.0-0.5-0.5-0.70.21.60.0
Bone: trabecular spacing0.71.12.4-0.91.11.3-0.61.1-1.1-1.3-1.1-1.0-1.0-1.5-0.10.0
Bone: trabecular thickness0.81.22.70.2-0.7-1.20.8-1.31.01.31.31.31.41.7-0.30.0
Bone: trabecular tissue density3.76.510.90.6-2.1-2.52.8-3.32.63.03.13.03.33.0-1.10.0
Water consumed over 24 hours0.10.10.40.4-0.5-0.4-0.10.10.30.2-0.1-0.1-0.20.40.60.0
Number of responses in last shaping day1.31.73.70.7-0.9-1.21.8-1.71.31.61.11.21.41.9-0.60.0