LOC120097346

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression LOC120097346 0.09 0.05 4.2e-09 0.07 0.06 0.06 0.07 5.1e-08 4.0e-07 8.6e-07 7.3e-08
2 LHb gene expression LOC120097346 0.17 0.11 8.3e-03 0.03 0.03 0.03 0.03 7.1e-02 5.7e-02 7.6e-02 6.6e-02
3 NAcc gene expression LOC120097346 0.13 0.07 1.8e-11 0.07 0.1 0.08 0.09 1.8e-08 4.9e-12 1.8e-09 9.5e-11
4 Brain gene expression LOC120097346 0.14 0.08 3.0e-08 0.03 0.08 0.08 0.06 4.0e-04 9.9e-08 1.5e-07 1.2e-06
5 PL intron excision ratio chr1_155447823_155454504 0.08 0.05 4.1e-07 0.06 0.06 0.06 0.06 2.9e-07 2.5e-07 4.1e-07 1.1e-07
6 PL intron excision ratio chr1_155447823_155454481 0.04 0.03 5.4e-03 0.02 0.01 0.02 0.02 1.2e-03 1.2e-02 1.4e-03 2.7e-03
7 PL gene expression LOC120097346 0.15 0.07 5.1e-14 0.13 0.13 0.13 0.13 1.9e-14 3.1e-14 2.2e-14 4.9e-14
8 Liver intron excision ratio chr1_155447823_155454481 0.07 0.05 6.7e-06 0.04 0.04 0.04 0.04 2.7e-05 3.2e-05 1.2e-05 1.8e-05
9 Liver intron excision ratio chr1_155447823_155454504 0.07 0.05 4.8e-06 0.04 0.04 0.04 0.04 2.4e-05 2.5e-05 1.3e-05 2.4e-05
10 NAcc intron excision ratio chr1_155439800_155454504 0.04 0.03 1.5e-03 0.02 0.02 0.02 0.02 1.7e-03 1.0e-03 1.9e-03 8.6e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.20.60.4-0.30.30.1-0.8-0.7-0.70.3-0.3-0.4
Area under the delay curve0.60.61.50.4-0.5-0.4-0.80.90.60.71.2-1.20.6
BMI with tail0.20.82.40.9-0.4-1.1-0.40.50.60.5-1.51.5-0.2
BMI without tail0.30.71.5-0.90.8-0.50.50.30.60.5-1.11.11.2
Body weight0.41.53.7-1.20.6-1.1-0.41.61.71.70.1-0.11.9
Weight adjusted by age0.20.20.5-0.70.70.10.40.10.20.3-0.40.40.6
Bone surface0.51.02.2-1.21.21.51.0-1.0-1.0-1.00.1-0.1-0.5
Bone volume0.30.41.1-1.00.91.00.6-0.6-0.5-0.40.3-0.3-0.4
Breakpoint value in progressive ratio session0.20.20.40.4-0.4-0.20.1-0.4-0.3-0.6-0.60.6-0.5
Number of licking bursts4.04.77.62.1-2.6-2.8-2.42.12.01.91.8-1.72.2
Context. condit. distance diff. score3.13.75.1-1.72.02.02.2-2.2-1.7-1.7-1.91.9-1.7
Locomotion velocity, session 10.50.50.90.9-0.40.10.2-1.0-0.8-0.9-0.80.8-0.9
Locomotion distance, session 11.82.23.1-0.81.11.31.5-1.8-1.6-1.6-1.71.7-1.5
Locomotion velocity, session 20.40.51.2-0.40.40.30.7-0.7-0.7-0.7-1.11.1-0.4
Locomotion distance, session 20.71.02.4-0.70.80.50.8-0.9-0.6-0.7-1.61.6-1.1
Locomotion velocity, session 31.01.11.9-0.90.81.31.2-1.4-1.2-1.2-0.70.7-1.1
Locomotion distance, session 32.22.44.2-0.81.11.81.7-2.0-1.9-1.8-1.21.2-1.5
Stereotopy head waving bouts, day 30.70.81.5-0.1-0.5-0.9-0.81.21.11.10.9-0.91.1
Stereotopy head waving duration, day 30.20.20.3-0.40.30.30.4-0.6-0.4-0.4-0.50.5-0.5
Locomotion velocity, session 70.10.10.40.6-0.4-0.40.0-0.2-0.1-0.2-0.50.5-0.3
Locomotion distance, session 70.50.61.10.7-0.5-0.7-0.81.10.91.00.6-0.60.4
Stereotopy head waving bouts, day 74.34.97.9-2.12.02.42.5-2.8-2.5-2.5-1.61.6-1.6
Stereotopy head waving duration, day 74.75.79.1-2.32.32.62.7-3.0-2.6-2.6-1.81.8-1.6
Locomotion velocity, session 81.21.42.2-1.41.31.31.5-1.5-1.2-1.2-0.90.9-0.8
Locomotion distance, session 82.84.25.4-2.12.11.92.2-2.2-1.6-1.6-2.32.3-1.9
Degree of sensitization distance3.33.47.40.1-0.7-1.8-1.72.72.52.51.3-1.31.9
Degree of sensitization stereotypy8.08.713.4-2.82.93.33.4-3.7-3.2-3.1-2.32.3-2.2
Conditioned locomotion0.91.01.90.2-0.5-0.5-1.21.41.31.31.2-1.2-0.0
Cocaine response after cond. corrected1.71.93.31.2-1.5-1.8-1.51.51.41.50.8-0.81.5
Cocaine response after cond. not corrected0.30.31.01.0-0.8-0.9-0.60.40.30.4-0.00.00.5
Cocaine response before conditioning3.64.47.1-0.71.52.12.2-2.7-2.5-2.5-2.02.0-2.1
Saline control response0.91.25.0-2.21.81.51.1-0.4-0.4-0.50.1-0.1-0.1
Bone: connectivity density0.91.43.40.50.10.90.9-1.9-1.8-1.7-0.80.8-1.1
Bone: cortical apparent density2.93.86.31.2-1.7-2.2-2.12.52.22.11.7-1.71.8
Bone: cortical area0.20.31.5-1.20.70.30.10.40.40.50.2-0.20.2
Bone: cortical porosity0.80.82.2-0.50.71.50.7-1.0-1.1-1.10.0-0.0-1.2
Bone: cortical porosity0.60.71.8-0.50.71.40.6-0.8-1.0-1.00.1-0.1-1.1
Bone: cortical thickness0.10.10.40.3-0.5-0.6-0.50.40.40.5-0.10.1-0.0
Bone: cortical thickness0.10.10.3-0.20.20.2-0.10.30.20.2-0.10.1-0.5
Bone: cortical tissue density2.83.76.21.2-1.7-2.2-2.12.52.22.11.6-1.61.8
Condit. Reinf. active minus inactive responses0.30.30.7-0.80.50.10.00.80.50.50.4-0.40.7
Condit. Reinf. active-inactive response ratio0.40.41.0-1.00.80.50.20.50.30.20.7-0.70.8
Condit. Reinf. active responses0.40.51.4-0.50.0-0.2-0.51.20.80.80.9-0.90.6
Condit. Reinf. inactive responses0.20.30.60.3-0.5-0.4-0.70.80.60.60.4-0.4-0.1
Incentive salience index mean0.20.30.8-0.80.50.2-0.10.90.40.30.5-0.60.5
Condit. Reinf. lever presses0.10.10.3-0.40.30.40.20.1-0.4-0.50.1-0.1-0.0
Condit. Reinf. active minus inactive responses4.55.613.7-3.73.52.82.8-1.7-1.6-1.6-1.51.5-0.8
Condit. Reinf. active-inactive response ratio1.71.82.7-1.51.61.51.6-1.4-1.3-1.3-1.01.0-0.7
Condit. Reinf. active responses4.86.720.2-4.54.13.03.0-1.5-1.4-1.5-1.61.6-0.7
Condit. Reinf. inactive responses2.22.711.0-3.32.81.91.6-0.4-0.3-0.4-0.70.7-0.2
Condit. Reinf. lever presses11.715.830.9-5.45.64.74.6-3.3-2.9-2.9-3.23.2-2.5
Condit. Reinf. lever reinforcers received6.08.422.9-4.84.43.53.4-1.9-1.9-2.0-1.81.8-1.0
Conditioned reinforcement - actives1.61.63.5-0.81.31.91.0-1.2-1.2-1.1-0.70.7-1.9
Conditioned reinforcement - inactives0.80.91.80.3-0.5-0.5-1.11.31.01.01.3-1.30.6
Conditioned locomotion3.23.85.8-1.21.72.21.9-2.3-2.0-2.1-1.71.7-2.4
Patch foraging indifference point 0 sec2.03.25.9-1.82.42.31.9-1.7-1.3-1.1-1.51.5-1.8
Patch foraging indifference point AUC0.30.41.0-0.70.2-0.4-0.10.80.70.70.2-0.21.0
Delay disc. indifference point, 0s delay0.30.41.5-1.20.90.60.6-0.2-0.2-0.1-0.40.4-0.3
Delay disc. indifference point, 16s delay0.91.02.40.5-0.6-0.3-1.01.10.90.91.6-1.60.3
Delay disc. indifference point, 2s delay0.40.41.7-1.30.80.60.50.0-0.3-0.10.5-0.50.6
Delay disc. indifference point, 24s delay2.32.23.01.2-1.4-1.3-1.71.71.41.61.7-1.70.9
Delay disc. indifference point, 4s delay0.40.42.0-1.40.80.20.30.50.40.40.3-0.30.7
Delay disc. indifference point, 8s delay0.20.20.40.3-0.2-0.1-0.50.60.30.40.7-0.7-0.1
Indifference point function ln k1.21.74.2-0.30.91.71.1-1.6-1.4-1.4-0.80.8-2.1
Indifference point function log k1.21.74.2-0.30.91.71.1-1.6-1.4-1.4-0.80.8-2.1
Patch foraging total patch changes 0 sec1.52.54.7-1.62.22.01.7-1.5-1.1-0.9-1.51.5-1.6
Patch foraging total patch changes 12 sec0.40.52.0-1.41.10.30.30.40.60.8-0.10.10.4
Patch foraging total patch changes 18 sec0.60.82.3-1.21.51.20.9-0.5-0.4-0.4-0.60.6-0.7
Patch foraging total patch changes 24 sec0.30.41.6-1.21.20.40.40.30.40.6-0.20.20.3
Patch foraging total patch changes 6 sec0.30.40.7-0.60.80.60.7-0.5-0.2-0.1-0.80.8-0.6
Patch foraging time to switch 0 sec2.43.77.02.5-2.7-2.1-2.21.61.31.11.9-1.91.2
Patch foraging water rate 0 sec1.93.15.3-1.92.32.11.9-1.6-1.3-1.1-1.71.7-1.6
Patch foraging water rate 12 sec2.64.08.4-1.11.91.62.0-1.9-1.4-1.2-2.92.9-2.2
Patch foraging water rate 18 sec2.02.74.6-1.91.91.32.0-1.4-1.1-0.9-2.22.2-0.7
Patch foraging water rate 24 sec1.11.63.7-0.31.01.31.0-1.2-1.1-1.1-1.51.5-1.9
Patch foraging water rate 6 sec1.42.03.1-1.01.41.41.4-1.3-1.3-1.0-1.81.8-1.7
Seeking ratio, delayed vs. immediate footshock0.50.52.21.5-1.2-0.5-0.7-0.3-0.4-0.30.5-0.5-0.1
Distance traveled before self-admin1.21.32.91.4-1.4-1.7-1.21.01.21.30.1-0.10.9
Distance traveled after self-admin0.50.51.3-0.1-0.20.00.6-1.1-0.6-0.6-1.11.1-0.8
Extensor digitorum longus weight0.20.71.80.4-0.4-1.1-0.70.81.11.00.2-0.21.3
Bone: elastic displacement0.60.72.61.6-1.6-1.1-0.6-0.1-0.2-0.1-0.00.00.1
Bone: elastic work0.81.04.62.1-1.7-0.9-0.5-0.8-0.6-0.4-0.50.5-0.3
Bone: endosteal estimation0.40.93.5-1.91.71.10.8-0.1-0.00.10.2-0.20.5
Bone: endosteal perimeter0.71.45.4-2.32.01.41.2-0.6-0.4-0.4-0.20.20.2
Epididymis fat weight0.92.23.90.9-1.0-1.9-1.41.81.91.80.7-0.72.0
Delta time in closed arm before/after self-admin4.84.78.11.1-1.2-2.3-2.12.82.82.71.7-1.72.4
Delta time in open arm before/after self-admin2.42.45.0-2.02.12.21.6-1.5-1.5-1.3-0.40.4-1.1
Diff in mean of infusions in LGA sessions2.12.34.00.8-1.7-1.6-1.51.41.00.91.9-1.92.0
Delay discount exponential model param0.60.61.3-0.50.60.40.8-0.9-0.5-0.6-1.11.1-0.6
Extinction: sum of active levers before priming0.10.10.10.2-0.3-0.3-0.20.30.1-0.10.3-0.30.2
Active lever presses in extinction session 63.93.76.0-1.01.32.01.8-2.4-2.1-2.2-1.81.8-2.4
Bone: final force0.91.53.1-0.0-0.4-0.4-1.21.51.41.41.8-1.80.6
Bone: final moment0.61.02.3-0.3-0.1-0.2-1.01.21.11.21.5-1.50.4
Food consumed during 24 hour testing period4.75.77.7-2.12.42.82.6-2.7-2.6-2.7-1.81.8-2.1
Glucose0.50.81.5-0.20.30.50.9-1.2-1.2-1.2-0.90.9-0.6
Heart weight1.01.42.2-1.21.41.51.3-1.4-1.2-1.2-0.90.9-1.0
Delay discount hyperbolic model param0.40.51.1-0.20.30.30.6-0.8-0.5-0.6-1.11.1-0.7
Intermittent access intake day 1-15 change2.02.04.3-1.01.00.91.4-1.6-1.3-1.1-2.12.1-1.0
Intermittent access intake escalation2.12.03.9-1.01.01.01.4-1.7-1.4-1.2-2.02.0-1.1
Intermittent access intake escalation 20.10.10.4-0.10.3-0.10.1-0.00.20.3-0.70.7-0.0
Intermitt. access day 1 inactive lever presses1.61.73.20.7-0.8-0.8-1.61.71.21.31.8-1.80.8
Intermitt. access day 15 inactive lever presses0.30.40.6-0.80.40.70.6-0.5-0.6-0.8-0.40.4-0.7
Intermitt. access escalation Index0.10.10.2-0.30.40.4-0.0-0.00.20.20.1-0.1-0.3
Intermittent access day 1 total infusions0.70.92.4-1.51.31.40.9-0.4-0.7-0.70.2-0.2-0.6
Intermittent access day 15 total infusions1.41.52.9-1.71.51.61.2-0.9-1.1-1.0-0.80.8-1.3
Intermittent access terminal intake (last 3 days)1.01.12.7-1.61.41.41.0-0.7-0.8-0.7-0.60.6-0.9
Intermittent access total infusions0.70.82.1-1.51.31.40.9-0.4-0.7-0.7-0.20.2-0.7
Intermittent access day 1 locomotion0.30.30.7-0.60.30.80.3-0.3-0.7-0.60.6-0.6-0.5
Intermittent access day 15 total locomotion2.02.13.3-1.21.31.71.5-1.6-1.8-1.8-1.11.1-1.4
Intermittent access total locomotion0.80.91.6-1.31.01.21.0-0.8-1.1-1.0-0.50.5-0.9
Intermittent access standard deviation0.10.10.6-0.20.1-0.10.10.0-0.10.1-0.80.8-0.1
Left kidney weight0.30.82.2-1.51.50.20.70.10.50.6-1.01.00.8
Right kidney weight0.20.51.0-1.00.9-0.10.10.70.81.0-0.20.20.8
Cocaine induced anxiety3.33.95.32.0-2.1-1.8-2.32.21.61.62.3-2.31.2
Post-drug Anxiety1.82.03.50.5-1.0-1.1-1.31.71.31.41.9-1.91.5
Baseline Anxiety1.21.23.4-1.81.61.41.4-1.0-0.8-0.8-0.40.4-0.1
Tail length1.23.516.3-4.02.70.81.40.60.80.80.5-0.52.7
Length with tail0.83.110.2-3.21.6-0.20.21.71.61.71.0-1.02.8
Length without tail0.20.40.70.0-0.6-0.6-0.70.90.70.70.6-0.60.4
Times rat made contact with spout0.40.41.4-0.1-0.4-0.6-0.50.70.40.50.8-0.81.2
Lifetime Intake1.21.32.8-1.71.61.61.2-0.7-0.9-0.9-0.60.6-0.9
Liver weight, left3.45.48.70.9-1.1-1.6-2.42.92.62.72.8-2.82.2
Liver weight, right4.88.013.30.6-1.4-2.4-2.73.63.33.33.0-3.03.3
Locomotor activity0.30.40.8-0.90.80.50.6-0.3-0.1-0.0-0.90.9-0.8
Locomotor testing distance1.01.74.2-2.11.91.21.5-0.7-0.5-0.4-1.41.4-0.9
Locomotor testing rearing0.30.52.9-1.71.00.20.40.40.50.4-0.10.10.6
Locomotion in novel chamber0.60.73.81.00.10.60.0-0.5-0.4-0.9-0.70.7-1.9
Locomotion in novel chamber post-restriction3.13.76.0-1.11.62.21.9-2.3-2.4-2.4-1.31.3-2.1
Fecal boli incidents, locomotor time 10.80.82.11.20.11.1-0.70.1-0.0-0.21.3-1.3-1.5
Change in fecal boli incidents, locomotor task0.40.41.20.4-0.7-1.1-0.30.60.70.7-0.10.11.0
Time >=10cm from walls, locomotor time 10.60.62.0-0.61.11.40.6-0.4-0.4-0.6-0.20.2-1.4
Bouts of movement, locomotor time 10.20.20.6-0.50.30.6-0.0-0.00.1-0.00.8-0.8-0.2
Total resting periods, locomotor time 10.20.20.40.00.00.6-0.1-0.2-0.2-0.30.6-0.6-0.7
Rest time, locomotor task time 10.10.10.30.2-0.10.40.0-0.2-0.3-0.20.5-0.5-0.4
Distance moved, locomotor task time 10.10.10.6-0.50.2-0.4-0.00.40.30.2-0.30.30.8
Vertical activity count, locomotor time 10.20.20.9-0.70.4-0.0-0.20.90.50.10.3-0.30.3
Time >=10cm from walls, locomotor time 20.70.73.3-1.81.41.00.70.10.10.2-0.00.0-0.4
Bouts of movement, locomotor time 21.82.04.0-0.70.1-0.4-1.11.81.82.01.7-1.71.2
Total resting periods, locomotor time 22.02.14.0-0.3-0.2-0.7-1.31.91.82.01.8-1.81.2
Rest time, locomotor task time 21.82.04.11.8-2.0-1.8-1.61.21.11.30.9-0.90.8
Distance moved, locomotor task time 21.82.05.4-2.32.11.61.6-1.0-0.9-1.0-1.11.1-0.6
Vertical activity count, locomotor time 20.40.51.5-1.21.00.5-0.00.90.60.20.6-0.60.2
Light reinforcement 11.52.76.12.5-2.4-2.5-1.71.11.21.40.3-0.31.1
Light reinforcement 21.11.53.60.9-0.4-0.20.8-1.5-1.3-1.2-1.91.9-0.8
Bone: marrow area0.30.72.7-1.71.50.90.60.10.10.20.4-0.40.6
Bone: maximum diameter0.81.55.8-2.42.01.51.3-0.6-0.5-0.5-0.40.4-0.1
Bone: maximum force0.30.51.6-0.3-0.00.1-0.60.70.70.81.3-1.30.3
Bone: maximum moment0.20.30.8-0.60.30.3-0.30.30.40.50.9-0.90.1
Mean time between licks in bursts1.52.19.2-3.02.61.20.90.80.90.70.1-0.10.6
Mean num. licks in bursts3.34.06.5-2.22.42.52.2-1.9-1.9-1.8-1.51.5-1.8
Cd content in liver0.50.51.40.7-0.7-0.8-0.70.70.50.50.7-0.71.2
Co content in liver0.70.93.8-2.01.41.10.60.20.10.10.7-0.70.4
Cu content in liver0.40.41.8-1.31.10.60.40.00.10.10.4-0.40.6
Fe content in liver0.20.31.0-0.2-0.10.0-0.30.30.20.11.0-1.00.5
K content in liver0.60.61.40.2-0.5-0.8-1.01.21.01.00.6-0.60.6
Mg content in liver0.10.10.2-0.40.40.20.2-0.1-0.1-0.1-0.30.3-0.2
Mn content in liver0.60.73.11.8-1.5-0.8-0.90.10.10.10.2-0.2-0.4
Na content in liver0.90.91.7-0.80.71.11.0-1.2-1.3-1.3-0.40.4-0.7
Rb content in liver0.70.81.8-1.31.11.30.9-0.8-1.0-1.00.1-0.1-0.2
Se content in liver2.12.65.32.2-2.3-1.7-1.91.20.90.81.7-1.70.9
Sr content in liver1.31.22.90.30.20.30.9-1.3-1.0-1.0-1.71.7-0.9
Zn content in liver3.53.86.1-1.82.52.22.1-1.8-1.6-1.5-2.12.1-1.7
Bone: minimum diameter0.61.12.7-1.70.8-0.2-0.21.11.11.20.8-0.81.5
Time in familiar zone, hab. session 10.10.10.2-0.30.2-0.20.30.00.10.1-0.40.40.5
Time in novel zone, hab. session 10.50.40.70.6-0.6-0.5-0.70.60.60.70.8-0.80.5
Total zone transitions, hab. session 11.01.42.5-0.50.30.81.2-1.6-1.6-1.6-1.21.2-0.9
Total locomotion distance, hab. session 11.62.34.30.2-0.8-1.7-1.32.02.02.10.8-0.81.9
Locomotion velocity, hab. session 11.21.73.30.1-0.6-1.5-1.21.81.81.80.7-0.71.4
Time in familiar zone, hab. session 20.50.51.9-1.11.41.00.8-0.00.10.0-0.30.3-0.2
Time in novel zone, hab. session 20.30.30.50.7-0.7-0.5-0.2-0.4-0.4-0.3-0.60.6-0.5
Total zone transitions, hab. session 23.44.46.4-1.91.71.92.4-2.5-2.2-2.2-2.12.1-1.6
Total locomotion distance, hab. session 21.01.33.1-1.00.2-1.0-0.61.61.81.70.1-0.11.2
Locomotion velocity, hab. session 21.11.53.6-1.00.1-1.2-0.71.71.91.90.3-0.31.5
Novel to familiar place preference ratio0.70.81.9-0.70.00.0-0.71.00.91.01.4-1.40.2
Novelty place preference0.70.71.7-0.80.00.0-0.61.00.90.91.3-1.30.2
Time in novel zone, NPP test0.60.71.5-0.90.20.2-0.50.90.90.91.2-1.20.0
Total zone transitions, NPP test1.21.72.8-0.50.60.91.2-1.7-1.6-1.6-1.61.6-1.3
Total locomotion distance, NPP test1.11.53.20.3-0.6-1.7-1.11.61.81.8-0.20.21.2
Locomotion velocity, NPP test1.21.73.70.6-0.9-1.9-1.21.71.81.8-0.10.11.3
Intraocular pressure1.21.74.60.60.31.21.0-2.0-2.1-1.9-0.60.6-1.2
Delta distance traveled before/after self-admin2.12.34.6-2.11.62.01.7-1.5-1.5-1.4-0.60.6-1.2
Delta ambulatory time before/after self-admin2.32.64.1-1.81.52.01.8-1.8-1.7-1.7-0.80.8-1.6
Parametrial fat weight0.40.82.31.2-1.0-1.5-0.70.50.70.5-0.20.21.4
Pavlov. Cond. lever latency0.60.82.01.4-1.3-1.4-0.90.60.80.80.1-0.10.5
Pavlov. Cond. magazine entry latency1.92.55.1-2.22.31.81.9-1.1-1.0-1.1-1.31.3-0.9
Pavlov. Cond. change in total contacts0.80.82.1-1.41.41.50.9-0.5-0.7-0.60.3-0.3-0.2
Pavlov. Cond. index score1.82.34.8-2.22.22.01.8-1.1-1.3-1.2-0.90.9-0.7
Pavlov. Cond. latency score1.62.04.6-2.12.11.91.6-1.0-1.1-1.1-0.60.6-0.8
Pavlov. Cond. lever contacts0.60.71.7-1.31.31.21.0-0.6-0.7-0.7-0.20.2-0.3
Pavlov. Cond. magazine entry number2.63.35.72.3-2.4-2.3-2.11.51.61.61.3-1.31.1
Pavlov. Cond. intertrial magazine entries0.60.81.40.8-1.2-0.8-1.00.80.40.51.2-1.20.6
Pavlov. Cond. lever-magazine prob. diff.1.62.03.9-2.02.01.91.7-1.1-1.3-1.3-0.80.8-0.7
Pavlov. Cond. response bias0.70.92.0-1.41.41.21.1-0.5-0.7-0.7-0.60.6-0.4
Pavlov. Cond. lever latency13.418.031.85.4-5.6-4.7-4.93.73.13.23.9-3.92.9
Pavlov. Cond. magazine entry latency5.56.310.2-2.12.52.22.7-2.6-2.0-2.0-3.23.2-2.3
Pavlov. Cond. change in total contacts13.218.226.9-5.25.24.55.0-4.1-3.5-3.5-4.14.1-2.8
Pavlov. Cond. index score11.514.723.7-4.64.94.14.4-3.5-2.9-2.9-3.83.8-2.8
Pavlov. Cond. latency score11.013.620.8-4.24.63.94.2-3.5-2.9-2.9-3.83.8-2.7
Pavlov. Cond. lever contacts13.918.933.4-5.65.84.95.0-3.8-3.3-3.4-3.83.8-2.9
Pavlov. Cond. magazine entry number8.510.412.83.0-3.5-3.2-3.63.42.82.83.6-3.62.7
Pavlov. Cond. intertrial magazine entries0.60.82.0-0.70.2-0.3-0.41.20.80.71.2-1.21.4
Pavlov. Cond. lever-magazine prob. diff.10.513.422.2-4.44.73.94.2-3.3-2.7-2.7-3.73.7-2.6
Pavlov. Cond. response bias15.220.733.9-5.65.85.05.2-4.1-3.5-3.6-4.34.3-3.2
Time in closed arm before self-admin4.04.56.8-1.41.52.12.2-2.4-2.2-2.0-2.22.2-2.6
Time in closed arm after self-admin0.50.61.21.1-1.0-0.7-0.90.80.70.60.5-0.5-0.1
Time in open arm before self-admin4.75.18.32.9-2.7-2.8-2.62.12.11.91.5-1.52.0
Time in open arm after self-admin0.20.20.6-0.10.3-0.1-0.30.40.50.50.5-0.50.8
Bone: periosteal estimation0.30.73.3-1.81.51.00.60.00.10.10.2-0.20.3
Bone: periosteal perimeter0.50.93.8-2.01.61.11.0-0.4-0.2-0.2-0.40.4-0.0
Bone: post-yield work0.00.10.2-0.30.40.30.2-0.10.10.1-0.10.1-0.2
Progressive ratio test 1 active lever presses0.00.00.1-0.3-0.00.10.2-0.2-0.4-0.40.1-0.10.1
Progressive ratio test 1 breakpoint0.00.00.1-0.40.00.10.2-0.1-0.3-0.30.1-0.10.3
Progressive ratio test 1 inactive lever presses0.20.20.7-0.70.70.80.3-0.0-0.3-0.50.2-0.2-0.4
Progressive ratio test 2 active lever presses0.50.51.9-1.41.01.10.6-0.1-0.5-0.60.4-0.4-0.2
Progressive ratio test 2 breakpoint0.50.52.1-1.51.01.10.6-0.1-0.5-0.50.4-0.4-0.1
Progressive ratio test 2 inactive lever presses0.60.71.7-1.10.91.30.6-0.4-0.7-0.9-0.00.0-1.1
Incentive Sensitization - Responses0.70.73.0-1.71.41.20.70.0-0.2-0.30.2-0.2-0.2
Incentive Sensitization - Breakpoint0.70.72.6-1.61.41.20.7-0.2-0.4-0.5-0.10.1-0.4
Sum of active levers in priming session hrs 5-60.20.20.4-0.5-0.2-0.20.4-0.3-0.3-0.5-0.70.7-0.2
Progressive ratio0.40.51.00.20.10.50.6-1.0-0.8-1.0-0.70.7-0.8
Food seeking constrained by brief footshock0.50.72.8-1.71.20.50.9-0.2-0.0-0.3-0.60.60.5
Seeking ratio, punishment vs. effort0.50.62.0-1.40.9-0.10.10.80.70.80.1-0.11.0
Retroperitoneal fat weight3.912.725.01.1-2.3-4.5-3.24.64.24.22.0-2.05.0
Reaction time number correct0.30.41.60.10.00.50.3-0.5-0.6-0.6-0.80.8-1.3
Reaction time mean minus median0.20.20.7-0.90.90.40.20.40.30.3-0.20.2-0.1
Reaction time mean minus median AUC0.30.41.0-0.91.00.90.4-0.0-0.0-0.1-0.40.4-0.8
Reaction time num false alarms3.85.26.81.6-2.0-2.3-2.62.62.42.62.3-2.31.8
Reaction time num false alarms AUC2.73.75.21.6-1.7-1.7-2.32.21.92.12.2-2.21.1
Reaction time trials correct on left0.30.41.60.10.00.50.3-0.5-0.6-0.6-0.80.8-1.3
Reaction time trials on left0.30.41.60.20.00.50.3-0.5-0.6-0.6-0.80.8-1.3
Reaction time mean2.73.77.11.0-1.3-1.7-2.12.72.32.02.0-2.01.5
Reaction time mean AUC2.53.36.01.1-1.5-1.6-2.12.52.01.72.1-2.11.4
Median of all reaction times3.44.68.01.5-1.8-2.0-2.52.82.42.12.3-2.31.5
Reaction time omissions0.50.71.80.5-0.8-1.1-1.01.31.00.80.5-0.50.6
Reaction time false alarm rate3.14.35.71.5-1.7-2.0-2.32.42.22.32.2-2.21.7
Reaction time premature initiation rate0.50.62.1-1.41.50.40.60.10.60.5-0.40.40.9
Reaction time premature initiations0.40.61.9-1.11.40.70.8-0.20.1-0.0-0.80.8-0.1
Std. dev. reaction times1.01.43.2-0.40.1-0.5-0.91.81.51.41.3-1.31.2
Reaction time trials completed0.30.41.60.20.00.50.3-0.5-0.6-0.6-0.80.8-1.3
Reaction time trials AUC0.20.21.10.10.00.30.2-0.2-0.3-0.3-0.70.6-1.1
Run reversals in cocaine runway, females1.31.35.0-0.50.0-1.4-0.41.41.21.4-0.00.02.2
Run reversals in cocaine runway, males0.20.20.40.5-0.30.1-0.20.2-0.2-0.50.6-0.6-0.1
Latency to leave start box in cocaine runway1.61.73.91.2-1.4-1.6-1.20.91.11.11.0-1.02.0
Latency to leave start box in cocaine runway, F1.92.15.60.8-1.2-1.7-1.31.31.41.51.3-1.32.4
Latency to leave start box in cocaine runway, M0.20.21.21.1-0.7-0.2-0.3-0.3-0.3-0.30.2-0.2-0.2
Std. dev. time between licks in bursts1.01.12.1-1.41.0-0.1-0.31.41.41.50.7-0.71.2
Total sessions with >9 infusions4.44.86.1-2.02.22.32.5-2.4-2.2-2.1-2.22.2-1.9
Short access day 1 total inactive lever presses0.40.41.6-0.2-0.20.2-0.60.80.10.21.3-1.30.0
Short access day 10 total inactive lever presses0.50.61.00.9-0.7-0.4-1.01.00.70.50.9-0.90.0
Short access day 1 total infusions1.51.63.6-1.91.91.71.3-0.7-0.9-0.8-0.70.7-0.9
Short access day 10 total infusions1.21.33.7-1.91.61.41.3-0.7-0.9-0.9-0.60.6-0.4
Short access total infusions1.01.22.6-1.61.51.31.2-0.8-0.8-0.7-0.80.8-0.6
Short access day 1 locomotion2.72.94.6-0.61.32.11.6-2.1-2.1-1.9-1.21.2-2.1
Short access day 10 total locomotion0.20.20.5-0.70.50.20.3-0.1-0.2-0.1-0.60.6-0.2
Short access total locomotion0.40.40.7-0.50.40.70.6-0.7-0.9-0.8-0.40.4-0.5
One hour access (0.3 mA shock)1.01.22.6-1.31.61.31.0-0.6-0.5-0.5-1.11.1-1.1
Compulsive drug intake0.30.31.51.2-0.50.1-0.3-0.3-0.4-0.40.1-0.1-0.7
One hour access (shock baseline)0.80.93.4-1.81.61.10.9-0.2-0.1-0.2-0.60.6-0.6
Social response proportion1.21.33.40.5-0.6-1.2-1.21.61.61.80.5-0.50.7
Social responses2.12.76.6-0.2-0.5-1.5-1.62.62.32.51.1-1.11.4
Social time1.31.73.81.5-2.0-1.7-1.51.31.11.00.9-0.90.6
Soleus weight1.02.95.40.2-0.4-1.6-1.62.32.32.31.3-1.32.1
Bone: stiffness2.03.15.6-0.0-0.7-0.9-1.72.22.02.02.4-2.41.5
Tibialis anterior weight0.10.51.1-0.60.3-0.4-0.40.91.11.10.6-0.60.8
Time to tail flick, vehicle, before self-admin0.40.40.9-0.90.20.20.7-0.9-0.7-0.7-0.70.7-0.2
Time to tail flick, vehicle, after self-admin3.63.86.4-1.71.92.52.1-2.4-2.2-2.2-1.11.1-1.8
Time to tail flick, test, before self-admin0.80.82.2-1.51.00.81.2-0.8-0.9-1.0-0.30.30.4
Time to tail flick, test, after self-admin0.50.62.5-1.60.90.20.30.30.40.60.4-0.41.1
Delta time to tail flick, vehicle, before/after SA1.61.53.5-0.41.31.91.1-1.4-1.5-1.4-0.50.5-1.4
Delta time to tail flick, test, before/after SA0.40.41.20.4-0.5-0.8-0.70.70.81.10.1-0.10.5
Tibia length1.23.37.3-1.91.92.71.6-1.7-1.8-1.8-0.60.6-2.3
Ambulatory time before self-admin1.01.12.21.5-1.4-1.5-1.10.81.01.00.3-0.30.7
Ambulatory time after self-admin0.60.71.6-0.3-0.00.50.8-1.2-0.9-0.8-0.80.8-1.1
Bone: tissue strength0.90.92.00.8-0.40.30.5-1.4-1.2-1.1-1.01.0-1.3
Total heroin consumption0.60.71.4-1.10.70.50.9-0.5-0.5-0.6-1.21.2-0.9
Bone: trabecular number0.20.41.21.1-1.1-0.4-0.3-0.5-0.6-0.60.2-0.2-0.2
Bone: trabecular spacing1.11.52.7-0.81.21.01.2-1.2-1.0-1.0-1.61.6-1.1
Bone: trabecular thickness1.21.43.1-0.1-0.6-0.6-1.01.31.21.31.8-1.81.0
Bone: trabecular tissue density5.07.012.90.2-1.3-2.1-2.53.63.03.03.1-3.12.8
Water consumed over 24 hours0.20.20.70.6-0.9-0.4-0.40.2-0.2-0.10.6-0.60.2
Number of responses in last shaping day0.40.51.4-0.50.30.3-0.40.80.30.51.2-1.20.4