Hub : Genes

Tenm4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr1_160112209_160192294 0.34 0.12 6.5e-05 0.04 0.04 0.04 0.04 1.2e-06 5.7e-07 8.2e-07 2.4e-07
2 Adipose gene expression Tenm4 0.08 0.06 2.3e-04 0 0.01 0.01 0.01 2.0e-01 4.0e-02 3.4e-02 7.0e-02
3 pVTA intron excision ratio chr1_160256484_160310038 0.02 0.02 8.7e-03 0.03 0.03 0.03 0.03 3.6e-03 4.1e-03 1.9e-03 3.3e-03
4 Brain mRNA stability Tenm4 0.09 0.06 8.4e-06 0.05 0.05 0.04 0.04 9.8e-06 1.1e-05 1.1e-04 7.8e-05
5 NAcc gene expression Tenm4 0.04 0.03 3.6e-04 0.02 0.02 0.02 0.02 2.8e-04 5.8e-04 4.4e-04 6.7e-04
6 Adipose intron excision ratio chr1_160112209_160192294 0.62 0.13 3.1e-11 0.09 0.1 0.1 0.1 6.4e-10 2.6e-11 7.6e-11 4.7e-11
7 Adipose intron excision ratio chr1_160137516_160192294 0.44 0.13 2.2e-07 0.06 0.06 0.07 0.07 1.2e-07 2.9e-07 2.5e-08 6.1e-08
8 PL alternative TSS XM_039113135.2 0.02 0.02 9.7e-03 0.01 0.01 0 0.01 5.0e-02 3.8e-02 1.9e-01 3.4e-02
9 Adipose mRNA stability Tenm4 0.05 0.07 8.0e-03 0.03 -0 0 0.01 7.4e-04 7.7e-01 1.0e-01 9.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.01.83.60.91.10.6-0.6-1.11.81.91.4-1.8
Area under the delay curve0.50.72.3-0.7-0.81.5-1.30.1-0.5-0.3-0.7-0.7
BMI with tail1.44.812.80.00.8-3.63.4-0.1-1.0-0.82.33.4
BMI without tail1.26.517.51.41.9-4.23.9-1.50.30.12.33.5
Body weight2.29.527.41.92.6-5.24.6-1.80.50.63.33.3
Weight adjusted by age0.82.47.21.61.6-2.42.7-0.6-0.2-0.1-0.11.7
Bone surface0.20.30.80.10.50.7-0.70.10.50.50.6-0.9
Bone volume0.20.40.80.50.80.2-0.1-0.40.70.80.9-0.7
Breakpoint value in progressive ratio session0.91.63.7-1.0-1.31.9-1.50.3-0.40.1-1.3-1.8
Number of licking bursts0.10.51.20.60.9-0.50.5-0.30.70.81.1-0.2
Context. condit. distance diff. score0.40.51.3-1.0-1.11.1-0.80.4-0.1-0.3-0.3-0.0
Locomotion velocity, session 11.31.52.7-0.8-1.51.5-1.41.5-0.8-0.8-1.6-0.7
Locomotion distance, session 11.62.13.9-1.2-1.81.0-0.92.0-1.5-1.6-1.90.3
Locomotion velocity, session 20.60.71.5-0.8-1.00.4-0.21.2-1.0-1.0-1.00.3
Locomotion distance, session 22.43.46.8-1.5-2.20.7-0.72.6-2.2-2.2-2.40.5
Locomotion velocity, session 30.20.20.70.50.20.3-0.5-0.10.10.1-0.9-0.7
Locomotion distance, session 30.50.61.2-0.2-0.61.1-1.10.30.0-0.0-1.0-1.1
Stereotopy head waving bouts, day 30.70.81.41.11.2-1.01.1-0.90.60.60.70.3
Stereotopy head waving duration, day 30.30.40.9-0.7-0.40.9-1.00.6-0.2-0.10.2-0.7
Locomotion velocity, session 71.82.03.7-1.9-1.91.9-1.91.5-0.8-0.8-0.6-0.4
Locomotion distance, session 71.62.04.1-1.9-2.01.6-1.61.3-1.0-1.1-0.9-0.1
Stereotopy head waving bouts, day 70.40.41.2-0.10.11.1-1.10.40.20.30.3-1.0
Stereotopy head waving duration, day 70.10.10.30.00.30.5-0.50.40.00.20.4-0.4
Locomotion velocity, session 82.63.26.7-2.3-1.92.6-2.42.1-0.9-0.7-0.1-1.2
Locomotion distance, session 82.02.86.1-2.0-2.51.7-1.42.0-1.4-1.5-1.70.1
Degree of sensitization distance1.01.13.2-1.4-0.8-0.50.40.7-1.2-1.20.41.8
Degree of sensitization stereotypy0.30.41.0-0.3-0.11.0-1.00.5-0.10.10.1-0.8
Conditioned locomotion2.42.84.2-1.5-1.82.1-2.01.9-1.5-1.2-1.9-0.8
Cocaine response after cond. corrected1.62.34.01.72.0-1.61.5-2.01.41.31.30.4
Cocaine response after cond. not corrected0.60.92.01.11.1-0.90.9-1.41.00.80.50.2
Cocaine response before conditioning0.70.81.8-0.5-1.01.3-1.30.6-0.1-0.2-0.9-1.1
Saline control response1.52.14.7-1.2-1.50.6-0.61.5-2.2-1.9-1.81.0
Bone: connectivity density1.11.84.50.60.71.0-1.0-0.91.81.81.0-2.1
Bone: cortical apparent density0.50.81.7-1.3-0.91.1-1.01.2-0.8-0.60.2-0.2
Bone: cortical area0.30.61.21.01.0-1.11.0-0.60.30.30.40.4
Bone: cortical porosity0.50.50.90.60.7-0.50.3-0.90.90.91.0-0.0
Bone: cortical porosity1.11.21.81.21.2-0.90.7-1.31.31.21.2-0.1
Bone: cortical thickness0.10.10.30.40.4-0.40.4-0.60.30.40.3-0.1
Bone: cortical thickness0.70.81.8-1.0-0.90.2-0.40.8-1.3-1.3-0.90.8
Bone: cortical tissue density0.50.81.5-1.2-0.91.1-1.01.2-0.7-0.50.1-0.3
Condit. Reinf. active minus inactive responses1.11.22.80.81.2-1.71.7-0.60.10.21.21.2
Condit. Reinf. active-inactive response ratio1.31.43.40.71.4-1.51.5-1.00.30.51.81.0
Condit. Reinf. active responses0.50.71.80.80.9-1.31.3-0.4-0.00.00.50.9
Condit. Reinf. inactive responses0.10.20.80.3-0.2-0.30.30.3-0.2-0.3-0.90.2
Incentive salience index mean0.60.81.70.81.0-1.31.3-0.40.30.31.00.7
Condit. Reinf. lever presses0.10.10.5-0.2-0.50.2-0.30.7-0.1-0.1-0.2-0.3
Condit. Reinf. active minus inactive responses2.84.37.7-2.4-2.41.3-1.42.8-2.6-2.4-1.41.0
Condit. Reinf. active-inactive response ratio1.21.93.7-1.9-1.71.2-1.21.9-1.5-1.3-0.30.4
Condit. Reinf. active responses4.05.710.2-2.3-2.61.0-1.13.2-3.2-3.0-2.31.6
Condit. Reinf. inactive responses0.81.22.40.0-0.4-0.80.70.7-1.4-1.4-1.51.5
Condit. Reinf. lever presses9.814.223.7-4.4-4.52.8-2.94.9-4.4-4.1-3.40.9
Condit. Reinf. lever reinforcers received4.25.911.3-2.5-2.61.0-1.13.4-3.2-3.1-2.21.5
Conditioned reinforcement - actives0.10.30.8-0.30.00.7-0.5-0.20.10.20.9-0.8
Conditioned reinforcement - inactives0.61.62.81.21.40.1-0.3-1.41.61.71.5-1.3
Conditioned locomotion0.81.22.30.70.60.9-0.5-1.51.31.30.7-1.5
Patch foraging indifference point 0 sec0.30.81.7-1.3-1.10.4-0.41.1-1.3-1.1-0.50.5
Patch foraging indifference point AUC0.00.10.30.3-0.30.00.0-0.20.40.2-0.6-0.1
Delay disc. indifference point, 0s delay0.80.92.10.3-0.0-1.11.3-0.0-1.0-1.0-1.01.4
Delay disc. indifference point, 16s delay1.82.65.0-1.9-2.02.2-2.11.0-1.4-1.3-1.3-0.4
Delay disc. indifference point, 2s delay0.10.10.4-0.1-0.00.3-0.4-0.1-0.3-0.1-0.2-0.6
Delay disc. indifference point, 24s delay0.81.44.1-0.8-1.02.0-1.90.4-0.20.0-0.6-1.5
Delay disc. indifference point, 4s delay0.70.72.00.61.0-0.50.7-1.40.50.71.40.2
Delay disc. indifference point, 8s delay0.81.33.3-1.0-1.21.8-1.50.7-0.6-0.6-1.4-0.6
Indifference point function ln k0.51.73.1-1.8-1.31.2-1.31.6-1.6-1.3-0.50.0
Indifference point function log k0.51.73.1-1.8-1.31.2-1.31.6-1.6-1.3-0.50.0
Patch foraging total patch changes 0 sec0.31.01.9-1.3-1.10.5-0.41.2-1.4-1.1-0.60.5
Patch foraging total patch changes 12 sec0.30.41.20.40.1-0.81.00.3-0.1-0.4-0.71.1
Patch foraging total patch changes 18 sec0.10.20.6-0.20.0-0.60.60.3-0.5-0.40.30.8
Patch foraging total patch changes 24 sec0.10.41.30.50.3-1.01.1-0.10.10.0-0.00.8
Patch foraging total patch changes 6 sec0.20.41.10.50.20.3-0.3-0.60.90.9-0.1-1.1
Patch foraging time to switch 0 sec0.93.66.92.52.6-1.51.5-1.42.32.01.6-0.6
Patch foraging water rate 0 sec0.83.06.5-2.5-2.31.7-1.71.3-2.0-1.7-1.00.2
Patch foraging water rate 12 sec1.87.214.9-3.9-3.52.8-2.72.5-3.0-2.4-1.4-0.3
Patch foraging water rate 18 sec2.35.110.4-3.2-2.91.4-1.22.3-2.9-2.7-1.11.2
Patch foraging water rate 24 sec0.91.33.4-1.9-1.21.1-0.91.3-1.3-0.90.50.3
Patch foraging water rate 6 sec3.04.410.0-3.2-2.42.5-2.61.8-2.2-1.6-0.4-0.5
Seeking ratio, delayed vs. immediate footshock0.40.61.00.80.9-1.00.6-1.00.60.60.70.3
Distance traveled before self-admin0.10.10.40.50.2-0.70.6-0.40.00.2-0.2-0.1
Distance traveled after self-admin1.12.03.71.91.1-1.51.3-1.91.71.5-0.3-0.6
Extensor digitorum longus weight0.62.56.1-1.4-1.4-0.91.01.1-2.0-2.2-1.02.5
Bone: elastic displacement0.30.30.8-0.8-0.90.6-0.60.1-0.5-0.5-0.60.1
Bone: elastic work0.20.20.7-0.6-0.80.5-0.5-0.1-0.3-0.3-0.6-0.2
Bone: endosteal estimation0.30.81.71.31.1-1.31.3-0.10.20.10.20.8
Bone: endosteal perimeter0.20.50.90.70.8-0.90.90.6-0.4-0.40.30.9
Epididymis fat weight0.62.810.00.41.6-2.11.9-1.50.60.83.21.3
Delta time in closed arm before/after self-admin2.12.04.9-1.4-1.0-0.10.21.4-2.2-1.9-1.31.8
Delta time in open arm before/after self-admin0.20.31.4-0.3-0.00.5-0.50.10.30.31.2-0.5
Diff in mean of infusions in LGA sessions0.30.62.3-0.3-0.20.9-1.00.40.60.70.3-1.5
Delay discount exponential model param0.60.82.60.70.8-1.61.4-0.00.40.20.60.9
Extinction: sum of active levers before priming0.40.71.3-1.1-0.70.6-0.21.0-1.1-1.0-0.40.7
Active lever presses in extinction session 60.80.82.0-0.9-1.10.8-0.80.9-0.9-0.7-1.4-0.5
Bone: final force0.20.41.20.2-0.30.6-0.70.8-0.1-0.2-1.1-0.8
Bone: final moment0.20.30.80.2-0.30.5-0.60.6-0.1-0.1-0.9-0.8
Food consumed during 24 hour testing period0.81.64.01.31.10.1-0.1-1.31.61.70.8-2.0
Glucose0.50.91.9-1.4-1.01.3-1.21.1-0.6-0.50.2-0.1
Heart weight1.52.45.0-2.2-1.40.4-0.51.3-2.2-2.1-0.41.6
Delay discount hyperbolic model param0.40.51.60.50.5-1.31.10.10.20.00.20.8
Intermittent access intake day 1-15 change0.10.81.40.0-0.10.8-0.8-1.11.21.10.7-1.0
Intermittent access intake escalation0.21.11.90.20.20.9-0.9-1.21.41.30.9-1.3
Intermittent access intake escalation 20.20.30.90.50.4-0.1-0.1-1.00.90.70.3-0.3
Intermitt. access day 1 inactive lever presses0.11.74.31.81.2-0.40.6-2.11.71.4-0.0-0.8
Intermitt. access day 15 inactive lever presses0.00.20.40.60.6-0.40.5-0.60.20.40.4-0.5
Intermitt. access escalation Index0.10.51.9-0.20.01.1-0.6-0.10.30.70.1-1.4
Intermittent access day 1 total infusions0.20.61.1-1.0-0.50.8-0.80.9-0.9-0.80.30.1
Intermittent access day 15 total infusions0.51.23.0-0.9-0.31.7-1.7-0.10.30.51.5-1.3
Intermittent access terminal intake (last 3 days)0.30.52.4-0.6-0.10.9-1.0-0.20.30.31.6-0.4
Intermittent access total infusions0.50.53.3-0.8-0.00.7-0.7-0.10.00.11.8-0.1
Intermittent access day 1 locomotion0.30.51.00.20.60.9-0.8-0.70.60.70.9-1.0
Intermittent access day 15 total locomotion0.20.71.3-0.10.21.2-1.2-0.30.90.81.1-0.9
Intermittent access total locomotion0.91.14.00.30.90.6-0.5-0.91.21.12.0-0.6
Intermittent access standard deviation0.20.82.30.50.6-1.51.3-0.90.30.21.00.9
Left kidney weight0.53.911.01.01.5-3.33.2-1.4-0.30.01.52.5
Right kidney weight0.64.213.20.71.0-3.63.5-0.7-0.6-0.61.02.9
Cocaine induced anxiety0.20.51.21.10.70.1-0.0-1.00.80.8-0.6-0.6
Post-drug Anxiety0.20.20.6-0.30.00.8-0.80.3-0.30.10.3-0.7
Baseline Anxiety1.32.14.9-2.1-1.20.9-1.02.2-1.9-1.40.90.1
Tail length0.84.17.72.02.4-2.82.4-2.51.11.01.71.6
Length with tail1.04.311.61.82.2-3.42.8-1.90.70.71.71.7
Length without tail0.31.54.31.31.4-2.11.7-1.00.40.81.10.2
Times rat made contact with spout0.10.10.4-0.2-0.0-0.70.50.3-0.2-0.10.60.3
Lifetime Intake0.20.31.3-0.8-0.20.4-0.40.3-0.4-0.21.20.2
Liver weight, left2.34.08.91.82.6-2.01.9-2.01.51.73.00.6
Liver weight, right2.64.69.31.72.4-2.42.2-2.31.71.83.11.0
Locomotor activity0.91.52.5-1.6-1.50.6-0.51.5-1.6-1.5-0.80.5
Locomotor testing distance1.43.48.0-1.9-1.4-0.60.72.0-2.8-2.7-0.82.1
Locomotor testing rearing0.93.48.8-1.7-1.0-1.00.91.8-2.5-2.60.03.0
Locomotion in novel chamber0.40.61.70.1-0.10.9-0.8-0.10.91.00.7-1.3
Locomotion in novel chamber post-restriction1.95.611.8-3.1-2.83.4-3.12.7-1.3-1.3-0.5-1.0
Fecal boli incidents, locomotor time 10.20.40.90.40.4-0.80.7-0.1-0.6-0.6-0.90.9
Change in fecal boli incidents, locomotor task0.50.62.1-0.5-0.10.5-0.7-0.00.40.71.4-1.1
Time >=10cm from walls, locomotor time 10.30.41.8-0.1-0.00.8-1.0-0.0-0.20.1-0.3-1.3
Bouts of movement, locomotor time 10.91.22.5-1.1-1.21.1-0.80.9-1.2-1.2-1.60.3
Total resting periods, locomotor time 11.11.22.3-1.2-1.31.5-1.20.8-0.9-0.9-1.4-0.2
Rest time, locomotor task time 10.50.71.9-0.7-0.71.2-0.91.4-0.8-0.4-0.2-0.8
Distance moved, locomotor task time 10.30.81.80.80.8-1.31.2-0.50.60.30.61.2
Vertical activity count, locomotor time 10.21.12.90.60.8-1.61.4-0.50.3-0.01.01.7
Time >=10cm from walls, locomotor time 20.10.41.20.70.5-1.10.8-0.7-0.0-0.0-0.40.4
Bouts of movement, locomotor time 20.31.14.6-0.3-0.8-0.00.10.8-1.2-1.3-2.20.8
Total resting periods, locomotor time 20.20.93.9-0.2-0.60.10.10.7-1.0-1.2-2.00.7
Rest time, locomotor task time 20.10.10.40.60.2-0.00.30.0-0.10.1-0.6-0.6
Distance moved, locomotor task time 20.81.12.80.61.0-1.71.5-0.40.20.00.81.5
Vertical activity count, locomotor time 21.12.55.01.11.7-2.22.1-1.10.40.41.81.9
Light reinforcement 10.10.51.1-0.4-0.5-0.50.60.4-0.9-1.0-1.00.9
Light reinforcement 20.10.20.50.40.20.3-0.3-0.40.60.50.1-0.7
Bone: marrow area0.30.71.61.31.1-1.21.2-0.10.20.10.20.8
Bone: maximum diameter0.30.61.40.60.8-1.21.10.2-0.4-0.40.11.1
Bone: maximum force0.30.51.40.0-0.30.9-0.90.90.10.1-0.6-1.2
Bone: maximum moment0.20.41.4-0.0-0.30.8-0.90.70.20.2-0.4-1.2
Mean time between licks in bursts0.21.24.8-0.20.2-1.31.50.3-1.0-0.80.62.2
Mean num. licks in bursts0.20.51.0-0.9-1.00.4-0.50.6-0.9-0.9-0.80.3
Cd content in liver0.70.72.0-0.70.0-0.60.50.6-1.3-1.10.31.4
Co content in liver1.92.24.7-1.1-0.9-0.40.41.4-2.1-2.2-1.91.8
Cu content in liver1.01.23.01.41.0-1.71.6-0.8-0.3-0.2-0.41.2
Fe content in liver0.20.20.50.70.5-0.50.3-0.60.60.4-0.3-0.1
K content in liver1.11.13.92.00.9-0.91.0-0.50.80.8-1.0-0.6
Mg content in liver0.70.72.31.50.4-1.11.1-0.30.00.2-1.3-0.1
Mn content in liver0.50.62.21.30.5-0.1-0.0-0.10.40.5-1.5-1.1
Na content in liver1.71.95.02.21.5-0.80.6-1.11.81.7-0.1-1.2
Rb content in liver0.20.30.60.40.10.7-0.7-0.00.20.2-0.7-0.7
Se content in liver2.02.46.12.51.8-1.21.0-2.11.51.6-0.3-1.0
Sr content in liver0.30.30.8-0.5-0.70.2-0.10.5-0.5-0.6-0.90.2
Zn content in liver2.32.75.4-0.3-0.9-1.61.60.8-2.0-2.1-2.02.3
Bone: minimum diameter1.73.45.12.22.2-2.22.2-1.71.41.41.70.8
Time in familiar zone, hab. session 10.10.10.3-0.4-0.30.4-0.4-0.20.40.30.6-0.2
Time in novel zone, hab. session 10.70.81.9-0.5-0.40.00.11.1-1.4-1.3-1.20.7
Total zone transitions, hab. session 10.71.02.3-0.5-1.00.8-0.91.5-0.9-0.9-1.4-0.5
Total locomotion distance, hab. session 13.04.311.32.32.1-3.43.3-1.60.70.50.41.8
Locomotion velocity, hab. session 13.95.512.92.82.4-3.63.5-2.21.21.00.81.6
Time in familiar zone, hab. session 20.70.81.7-1.3-0.90.8-0.90.3-1.0-1.0-0.60.6
Time in novel zone, hab. session 20.50.61.61.00.8-1.11.3-0.30.40.40.40.4
Total zone transitions, hab. session 20.60.82.2-0.6-1.20.5-0.51.2-0.8-0.9-1.5-0.0
Total locomotion distance, hab. session 23.14.010.82.11.7-3.23.3-1.70.60.50.41.8
Locomotion velocity, hab. session 22.83.810.82.11.5-3.33.3-1.50.40.2-0.11.9
Novel to familiar place preference ratio0.20.20.50.70.50.1-0.1-0.20.70.60.0-0.7
Novelty place preference0.10.10.20.50.20.2-0.10.10.40.3-0.2-0.5
Time in novel zone, NPP test0.10.10.30.0-0.20.5-0.40.50.0-0.0-0.4-0.4
Total zone transitions, NPP test0.81.22.1-1.2-1.51.4-1.31.4-0.7-0.6-0.9-0.6
Total locomotion distance, NPP test2.23.07.91.81.6-2.72.8-1.61.00.70.71.4
Locomotion velocity, NPP test2.73.89.12.21.9-3.03.0-1.91.21.00.81.3
Intraocular pressure1.83.05.8-2.4-1.82.1-2.21.9-1.6-1.5-0.4-0.2
Delta distance traveled before/after self-admin0.10.10.50.40.1-0.20.1-0.40.70.3-0.5-0.1
Delta ambulatory time before/after self-admin0.10.10.30.1-0.1-0.1-0.1-0.40.60.1-0.60.1
Parametrial fat weight0.61.43.50.50.9-1.91.6-1.10.50.41.71.2
Pavlov. Cond. lever latency0.10.10.30.30.3-0.40.5-0.4-0.1-0.2-0.40.5
Pavlov. Cond. magazine entry latency0.70.91.8-1.1-1.1-0.10.11.1-1.2-1.3-0.51.2
Pavlov. Cond. change in total contacts0.70.72.80.40.8-0.30.2-0.51.01.11.7-0.5
Pavlov. Cond. index score0.30.40.9-0.7-0.7-0.10.00.9-0.7-0.8-0.10.6
Pavlov. Cond. latency score0.10.10.3-0.3-0.3-0.20.00.6-0.3-0.40.20.3
Pavlov. Cond. lever contacts0.00.00.1-0.0-0.1-0.30.20.3-0.0-0.10.20.2
Pavlov. Cond. magazine entry number1.11.32.81.41.2-0.20.2-1.71.41.50.4-1.1
Pavlov. Cond. intertrial magazine entries1.92.34.11.71.7-0.50.6-1.82.02.01.4-1.0
Pavlov. Cond. lever-magazine prob. diff.0.20.30.8-0.7-0.70.1-0.20.9-0.5-0.6-0.00.3
Pavlov. Cond. response bias0.20.30.8-0.7-0.7-0.10.10.9-0.6-0.7-0.10.6
Pavlov. Cond. lever latency14.220.031.35.35.6-3.43.3-5.45.04.84.3-1.2
Pavlov. Cond. magazine entry latency3.75.210.8-3.3-3.01.8-1.82.3-2.6-2.4-1.50.8
Pavlov. Cond. change in total contacts4.911.818.9-4.2-4.21.9-1.83.8-4.3-4.1-3.12.1
Pavlov. Cond. index score8.813.821.9-4.6-4.72.6-2.54.1-4.4-4.1-3.41.4
Pavlov. Cond. latency score7.311.819.4-4.4-4.42.6-2.53.8-3.9-3.7-3.11.1
Pavlov. Cond. lever contacts12.919.129.6-5.3-5.43.3-3.25.2-5.0-4.8-4.11.4
Pavlov. Cond. magazine entry number8.210.719.44.44.1-2.72.7-3.53.83.52.4-0.9
Pavlov. Cond. intertrial magazine entries1.43.17.12.41.9-2.62.7-1.30.90.80.61.3
Pavlov. Cond. lever-magazine prob. diff.8.212.620.0-4.5-4.52.5-2.44.0-4.2-4.0-3.21.4
Pavlov. Cond. response bias14.720.330.7-5.4-5.53.1-3.05.3-5.3-5.1-4.21.8
Time in closed arm before self-admin0.00.10.1-0.2-0.3-0.30.10.1-0.1-0.3-0.40.0
Time in closed arm after self-admin0.20.20.5-0.5-0.4-0.20.20.2-0.7-0.5-0.40.4
Time in open arm before self-admin0.40.52.00.0-0.2-0.40.60.3-0.9-0.8-1.40.7
Time in open arm after self-admin0.00.00.10.30.10.10.00.10.20.2-0.1-0.0
Bone: periosteal estimation0.51.22.31.51.5-1.51.5-0.60.50.50.60.7
Bone: periosteal perimeter0.20.30.80.50.5-0.80.80.3-0.3-0.4-0.00.9
Bone: post-yield work0.40.72.50.60.30.5-0.5-0.31.21.20.1-1.6
Progressive ratio test 1 active lever presses0.20.30.70.10.30.4-0.5-0.60.40.60.8-0.8
Progressive ratio test 1 breakpoint0.20.30.80.10.30.5-0.5-0.60.40.60.8-0.9
Progressive ratio test 1 inactive lever presses0.10.31.10.20.40.5-0.5-0.80.20.60.2-1.1
Progressive ratio test 2 active lever presses0.30.42.2-0.40.00.6-0.5-0.30.30.21.50.2
Progressive ratio test 2 breakpoint0.30.42.1-0.40.00.6-0.5-0.30.30.21.40.2
Progressive ratio test 2 inactive lever presses0.10.31.0-1.0-0.60.5-0.70.3-0.5-0.40.6-0.0
Incentive Sensitization - Responses0.10.20.6-0.6-0.20.2-0.10.0-0.4-0.20.80.6
Incentive Sensitization - Breakpoint0.10.20.5-0.6-0.30.3-0.10.0-0.3-0.20.70.6
Sum of active levers in priming session hrs 5-60.10.10.20.0-0.20.30.1-0.20.30.40.1-0.1
Progressive ratio0.51.65.3-0.5-1.2-0.60.41.0-1.1-1.5-2.31.4
Food seeking constrained by brief footshock2.02.55.6-1.2-1.0-0.60.91.5-2.2-2.1-1.32.4
Seeking ratio, punishment vs. effort0.71.54.01.01.6-1.11.3-1.20.71.02.00.6
Retroperitoneal fat weight2.611.825.61.43.1-4.84.7-2.70.70.85.14.0
Reaction time number correct0.10.21.2-0.2-0.60.4-0.20.3-0.4-0.2-1.1-0.3
Reaction time mean minus median0.21.42.6-1.1-1.1-0.60.71.1-1.6-1.6-0.81.6
Reaction time mean minus median AUC0.10.71.3-0.8-0.7-0.50.51.0-1.1-1.1-0.51.0
Reaction time num false alarms2.95.07.42.72.7-2.62.3-2.52.12.01.80.3
Reaction time num false alarms AUC1.94.46.32.42.5-2.32.0-2.42.12.02.10.1
Reaction time trials correct on left0.10.21.2-0.2-0.60.4-0.20.3-0.4-0.2-1.1-0.3
Reaction time trials on left0.10.31.3-0.3-0.60.4-0.20.4-0.4-0.2-1.1-0.3
Reaction time mean0.30.61.20.1-0.2-1.10.81.0-0.5-0.7-0.71.0
Reaction time mean AUC0.10.41.10.30.1-1.10.70.8-0.2-0.4-0.30.6
Median of all reaction times0.20.41.00.50.0-1.00.71.0-0.0-0.3-0.60.5
Reaction time omissions0.50.72.0-0.7-0.5-0.90.90.8-0.9-0.9-0.01.4
Reaction time false alarm rate2.73.85.32.12.3-1.91.7-2.22.01.92.20.0
Reaction time premature initiation rate0.30.52.4-0.2-0.0-0.71.0-0.3-0.2-0.60.21.6
Reaction time premature initiations0.10.41.6-0.6-0.4-0.40.80.1-0.6-0.7-0.21.3
Std. dev. reaction times0.51.74.3-0.6-0.5-1.31.31.2-1.5-1.6-0.72.1
Reaction time trials completed0.10.31.3-0.3-0.60.4-0.20.4-0.4-0.2-1.1-0.3
Reaction time trials AUC0.10.21.3-0.3-0.50.2-0.00.4-0.5-0.3-1.1-0.0
Run reversals in cocaine runway, females1.82.06.21.40.7-2.02.5-0.80.60.1-0.22.2
Run reversals in cocaine runway, males3.64.09.0-2.8-2.21.8-1.93.0-2.1-1.7-0.0-0.1
Latency to leave start box in cocaine runway1.72.35.72.41.7-1.61.7-1.61.41.3-0.7-0.5
Latency to leave start box in cocaine runway, F1.92.45.82.41.5-1.92.1-1.31.30.9-1.30.1
Latency to leave start box in cocaine runway, M0.60.61.40.90.9-0.60.5-1.20.60.90.3-0.7
Std. dev. time between licks in bursts0.40.71.50.60.9-1.11.2-0.90.20.41.00.7
Total sessions with >9 infusions0.50.61.4-0.2-0.3-0.80.90.2-1.0-0.9-0.91.2
Short access day 1 total inactive lever presses0.20.31.20.40.6-0.10.2-0.60.40.71.1-0.4
Short access day 10 total inactive lever presses0.00.10.20.30.20.1-0.10.00.30.1-0.1-0.4
Short access day 1 total infusions0.30.71.9-0.6-0.2-0.60.80.6-1.1-0.80.41.4
Short access day 10 total infusions0.30.51.3-0.3-0.0-0.80.80.4-1.1-0.9-0.31.0
Short access total infusions0.40.61.6-0.6-0.3-0.60.70.6-1.2-1.0-0.41.1
Short access day 1 locomotion0.30.51.1-0.7-0.60.5-0.50.9-1.0-0.8-0.8-0.1
Short access day 10 total locomotion0.00.10.10.00.1-0.10.1-0.20.40.20.20.3
Short access total locomotion0.20.20.70.60.5-0.40.4-0.80.40.3-0.40.3
One hour access (0.3 mA shock)0.70.81.7-1.3-1.01.1-0.90.8-0.8-0.90.20.4
Compulsive drug intake0.71.02.61.10.50.10.0-1.11.61.40.2-1.3
One hour access (shock baseline)0.71.93.9-2.0-1.61.7-1.71.3-1.3-1.2-0.2-0.0
Social response proportion0.40.51.30.80.5-1.20.8-1.00.80.50.20.3
Social responses0.40.51.1-0.9-0.7-0.50.10.3-0.9-1.0-0.41.1
Social time1.42.23.51.91.6-1.81.8-1.91.31.20.60.5
Soleus weight0.92.76.91.11.4-2.62.5-1.70.2-0.00.82.0
Bone: stiffness0.30.52.00.50.30.7-0.80.30.70.80.3-1.4
Tibialis anterior weight0.20.61.9-0.2-0.4-0.90.90.5-0.7-0.8-0.51.4
Time to tail flick, vehicle, before self-admin0.40.51.7-0.9-0.81.3-1.00.4-0.2-0.4-0.4-0.1
Time to tail flick, vehicle, after self-admin0.91.84.0-1.7-1.40.5-0.71.4-2.0-1.9-0.90.8
Time to tail flick, test, before self-admin0.50.51.60.60.8-1.21.3-0.1-0.6-0.30.20.7
Time to tail flick, test, after self-admin2.22.37.50.40.3-1.92.1-0.1-1.2-1.3-1.32.7
Delta time to tail flick, vehicle, before/after SA0.60.61.4-0.8-0.9-0.1-0.30.6-1.2-1.1-1.00.4
Delta time to tail flick, test, before/after SA0.30.30.70.50.0-0.50.5-0.80.50.1-0.90.8
Tibia length0.10.41.31.00.4-0.70.7-0.3-0.3-0.2-1.10.1
Ambulatory time before self-admin0.10.30.70.50.3-0.10.1-0.50.50.80.7-0.9
Ambulatory time after self-admin0.50.81.81.00.5-0.40.3-1.21.31.2-0.1-1.0
Bone: tissue strength2.32.45.20.40.60.9-1.0-0.82.12.32.2-2.3
Total heroin consumption0.70.82.1-1.5-1.30.5-0.40.7-1.1-0.9-0.70.2
Bone: trabecular number0.81.64.20.60.51.1-1.0-1.01.61.60.7-2.1
Bone: trabecular spacing0.30.40.8-0.6-0.7-0.40.30.6-0.9-0.9-0.50.8
Bone: trabecular thickness0.10.10.50.10.60.00.10.1-0.10.00.70.3
Bone: trabecular tissue density0.20.30.60.70.6-0.70.50.1-0.4-0.2-0.50.5
Water consumed over 24 hours0.10.30.80.00.20.3-0.2-0.30.60.70.8-0.9
Number of responses in last shaping day0.60.81.80.71.1-1.41.1-0.4-0.6-0.60.51.3