Hub : Genes

Tenm4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr1_160112209_160192294 0.34 0.12 6.5e-05 0.04 0.04 0.04 0.04 1.2e-06 5.7e-07 8.2e-07 2.4e-07
2 Adipose gene expression Tenm4 0.08 0.06 2.3e-04 0 0.01 0.01 0 2.0e-01 4.0e-02 3.4e-02 7.6e-02
3 pVTA intron excision ratio chr1_160256484_160310038 0.02 0.02 8.7e-03 0.03 0.03 0.03 0.03 3.6e-03 4.1e-03 1.9e-03 3.2e-03
4 Brain mRNA stability Tenm4 0.09 0.06 8.4e-06 0.05 0.05 0.04 0.04 9.8e-06 1.1e-05 1.1e-04 7.9e-05
5 NAcc gene expression Tenm4 0.04 0.03 3.6e-04 0.02 0.02 0.02 0.02 2.8e-04 5.8e-04 4.3e-04 6.9e-04
6 Adipose intron excision ratio chr1_160112209_160192294 0.62 0.13 3.1e-11 0.09 0.1 0.1 0.1 6.4e-10 2.6e-11 8.7e-11 5.1e-11
7 Adipose intron excision ratio chr1_160137516_160192294 0.44 0.13 2.2e-07 0.06 0.06 0.07 0.07 1.2e-07 2.9e-07 2.5e-08 6.0e-08
8 PL alternative TSS XM_039113135.2 0.02 0.02 9.7e-03 0.01 0.01 0 0.01 5.0e-02 3.8e-02 1.9e-01 3.6e-02
9 Adipose mRNA stability Tenm4 0.05 0.07 8.0e-03 0.03 -0 0 0.01 7.4e-04 7.7e-01 1.0e-01 1.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.11.83.60.9-1.1-0.60.61.11.8-1.91.41.8
Area under the delay curve0.60.72.3-0.70.8-1.51.3-0.1-0.50.3-0.70.7
BMI with tail1.44.812.80.0-0.83.6-3.40.1-1.00.82.3-3.4
BMI without tail2.16.517.51.4-1.94.2-3.91.50.3-0.12.3-3.5
Body weight2.29.527.42.0-2.65.2-4.61.80.5-0.63.3-3.3
Weight adjusted by age1.62.47.21.6-1.62.4-2.70.6-0.20.1-0.1-1.7
Bone surface0.20.30.80.1-0.5-0.70.7-0.10.5-0.50.60.9
Bone volume0.20.40.80.5-0.8-0.20.10.40.7-0.80.90.7
Breakpoint value in progressive ratio session1.31.63.7-1.01.3-1.91.5-0.3-0.4-0.1-1.31.8
Number of licking bursts0.30.51.20.6-0.90.5-0.50.30.7-0.81.10.2
Context. condit. distance diff. score0.40.51.3-0.91.1-1.10.8-0.4-0.10.3-0.30.0
Locomotion velocity, session 11.41.52.7-0.81.5-1.51.4-1.5-0.80.8-1.60.7
Locomotion distance, session 11.62.13.9-1.21.8-1.00.9-2.0-1.51.6-1.9-0.3
Locomotion velocity, session 20.60.71.5-0.81.0-0.40.2-1.2-1.01.0-1.0-0.3
Locomotion distance, session 22.43.46.8-1.52.2-0.70.7-2.6-2.22.2-2.4-0.5
Locomotion velocity, session 30.20.20.70.5-0.2-0.30.50.10.1-0.1-0.90.7
Locomotion distance, session 30.50.61.2-0.20.6-1.11.1-0.30.00.0-1.01.1
Stereotopy head waving bouts, day 30.70.81.41.1-1.21.0-1.10.90.6-0.60.7-0.3
Stereotopy head waving duration, day 30.30.40.9-0.70.4-0.91.0-0.6-0.20.10.20.7
Locomotion velocity, session 71.92.03.6-1.91.9-1.91.9-1.5-0.80.8-0.60.4
Locomotion distance, session 71.62.04.1-1.92.0-1.61.6-1.3-1.01.1-0.90.1
Stereotopy head waving bouts, day 70.40.41.2-0.1-0.1-1.11.1-0.40.2-0.30.31.0
Stereotopy head waving duration, day 70.10.10.30.0-0.3-0.50.5-0.40.0-0.20.40.4
Locomotion velocity, session 82.63.26.7-2.21.9-2.62.4-2.1-0.90.7-0.11.2
Locomotion distance, session 82.02.86.1-1.92.5-1.71.4-2.0-1.41.5-1.7-0.1
Degree of sensitization distance1.01.13.2-1.30.80.5-0.4-0.7-1.21.20.4-1.8
Degree of sensitization stereotypy0.30.41.0-0.30.1-1.01.0-0.5-0.1-0.10.10.8
Conditioned locomotion2.42.84.2-1.51.8-2.12.0-1.9-1.51.2-1.90.8
Cocaine response after cond. corrected1.92.34.01.7-2.01.6-1.52.01.4-1.31.3-0.4
Cocaine response after cond. not corrected0.80.92.01.1-1.10.9-0.91.41.0-0.80.5-0.2
Cocaine response before conditioning0.70.81.8-0.51.0-1.31.3-0.6-0.10.2-0.91.1
Saline control response1.62.14.7-1.31.5-0.60.6-1.5-2.21.9-1.8-1.0
Bone: connectivity density1.11.84.50.7-0.7-1.01.00.91.8-1.81.02.1
Bone: cortical apparent density0.60.81.7-1.30.9-1.11.0-1.2-0.80.60.20.2
Bone: cortical area0.40.61.21.0-1.01.1-1.00.60.3-0.30.4-0.4
Bone: cortical porosity0.50.50.90.6-0.70.5-0.30.90.9-0.91.00.0
Bone: cortical porosity1.11.21.81.2-1.20.9-0.71.31.3-1.21.20.1
Bone: cortical thickness0.10.10.30.4-0.40.4-0.40.60.3-0.40.30.1
Bone: cortical thickness0.70.81.8-1.00.9-0.20.4-0.8-1.31.3-0.9-0.8
Bone: cortical tissue density0.60.81.5-1.20.9-1.11.0-1.2-0.70.50.10.3
Condit. Reinf. active minus inactive responses1.11.22.80.8-1.21.7-1.70.60.1-0.21.2-1.2
Condit. Reinf. active-inactive response ratio1.31.43.40.7-1.41.5-1.51.00.3-0.51.8-1.0
Condit. Reinf. active responses0.50.71.80.8-0.91.3-1.30.4-0.0-0.00.5-0.9
Condit. Reinf. inactive responses0.10.20.80.30.20.3-0.3-0.3-0.20.3-0.9-0.2
Incentive salience index mean0.60.81.70.8-1.01.3-1.30.40.3-0.31.0-0.7
Condit. Reinf. lever presses0.10.10.5-0.20.5-0.20.3-0.7-0.10.1-0.20.3
Condit. Reinf. active minus inactive responses3.34.37.7-2.52.4-1.31.4-2.8-2.62.4-1.4-1.0
Condit. Reinf. active-inactive response ratio1.61.93.7-1.91.7-1.21.2-1.9-1.51.3-0.3-0.4
Condit. Reinf. active responses4.15.710.2-2.32.6-1.01.1-3.2-3.23.0-2.3-1.6
Condit. Reinf. inactive responses0.91.22.4-0.00.40.8-0.7-0.7-1.41.4-1.5-1.5
Condit. Reinf. lever presses10.314.223.7-4.44.5-2.82.9-4.9-4.44.1-3.4-0.9
Condit. Reinf. lever reinforcers received4.35.911.3-2.52.6-1.01.1-3.4-3.23.1-2.2-1.5
Conditioned reinforcement - actives0.10.30.8-0.3-0.0-0.70.50.20.1-0.20.90.8
Conditioned reinforcement - inactives1.11.62.81.2-1.4-0.10.31.41.6-1.71.51.3
Conditioned locomotion0.91.22.30.7-0.6-0.90.51.51.3-1.30.71.5
Patch foraging indifference point 0 sec0.50.81.7-1.31.1-0.40.4-1.1-1.31.1-0.5-0.5
Patch foraging indifference point AUC0.10.10.30.30.3-0.0-0.00.20.4-0.2-0.60.1
Delay disc. indifference point, 0s delay0.80.92.10.20.01.1-1.30.0-1.01.0-1.0-1.4
Delay disc. indifference point, 16s delay2.42.65.0-1.92.0-2.22.1-1.0-1.41.3-1.30.4
Delay disc. indifference point, 2s delay0.10.10.4-0.10.0-0.30.40.1-0.30.1-0.20.6
Delay disc. indifference point, 24s delay1.21.44.1-0.81.0-2.01.9-0.4-0.2-0.0-0.61.5
Delay disc. indifference point, 4s delay0.70.72.00.6-1.00.5-0.71.40.5-0.71.4-0.2
Delay disc. indifference point, 8s delay1.11.33.3-1.01.2-1.81.5-0.7-0.60.6-1.40.6
Indifference point function ln k1.01.73.1-1.81.3-1.21.3-1.6-1.61.3-0.5-0.0
Indifference point function log k1.01.73.1-1.81.3-1.21.3-1.6-1.61.3-0.5-0.0
Patch foraging total patch changes 0 sec0.51.01.9-1.31.1-0.50.4-1.2-1.41.1-0.6-0.5
Patch foraging total patch changes 12 sec0.30.41.20.4-0.10.8-1.0-0.3-0.10.4-0.7-1.1
Patch foraging total patch changes 18 sec0.10.20.6-0.2-0.00.6-0.6-0.3-0.50.40.3-0.8
Patch foraging total patch changes 24 sec0.20.41.30.5-0.31.0-1.10.10.1-0.0-0.0-0.8
Patch foraging total patch changes 6 sec0.30.41.10.5-0.2-0.30.30.60.9-0.9-0.11.1
Patch foraging time to switch 0 sec1.73.66.92.5-2.61.5-1.51.42.3-2.01.60.6
Patch foraging water rate 0 sec1.43.06.5-2.52.3-1.71.7-1.3-2.01.7-1.0-0.2
Patch foraging water rate 12 sec3.47.214.9-3.93.5-2.82.7-2.5-3.02.4-1.40.3
Patch foraging water rate 18 sec3.35.110.4-3.22.9-1.41.2-2.3-2.92.7-1.1-1.2
Patch foraging water rate 24 sec0.91.23.4-1.81.2-1.10.9-1.3-1.30.90.5-0.3
Patch foraging water rate 6 sec3.04.410.0-3.22.4-2.52.6-1.8-2.21.6-0.40.5
Seeking ratio, delayed vs. immediate footshock0.50.61.00.8-0.91.0-0.61.00.6-0.60.7-0.3
Distance traveled before self-admin0.10.10.40.5-0.20.7-0.60.40.0-0.2-0.20.1
Distance traveled after self-admin1.62.03.71.9-1.11.5-1.31.91.7-1.5-0.30.6
Extensor digitorum longus weight0.62.56.1-1.41.40.9-1.0-1.1-2.02.2-1.0-2.5
Bone: elastic displacement0.30.30.8-0.80.9-0.60.6-0.1-0.50.5-0.6-0.1
Bone: elastic work0.20.20.7-0.60.8-0.50.50.1-0.30.3-0.60.2
Bone: endosteal estimation0.30.81.61.3-1.11.3-1.30.10.2-0.10.2-0.8
Bone: endosteal perimeter0.20.50.90.6-0.80.9-0.9-0.6-0.40.40.3-0.9
Epididymis fat weight0.82.810.00.4-1.62.1-1.91.50.6-0.83.2-1.3
Delta time in closed arm before/after self-admin2.22.04.9-1.41.00.1-0.2-1.4-2.21.9-1.3-1.8
Delta time in open arm before/after self-admin0.30.31.4-0.30.0-0.50.5-0.10.3-0.31.20.5
Diff in mean of infusions in LGA sessions0.50.62.3-0.20.2-0.91.0-0.40.6-0.70.31.5
Delay discount exponential model param0.70.82.60.7-0.81.6-1.40.00.4-0.20.6-0.9
Extinction: sum of active levers before priming0.60.71.3-1.10.7-0.60.2-1.0-1.11.0-0.4-0.7
Active lever presses in extinction session 60.80.82.0-0.91.1-0.80.8-0.9-0.90.7-1.40.5
Bone: final force0.20.41.20.20.3-0.60.7-0.8-0.10.2-1.10.8
Bone: final moment0.20.30.80.20.3-0.50.6-0.6-0.10.1-0.90.8
Food consumed during 24 hour testing period1.21.64.01.3-1.1-0.10.11.31.6-1.70.82.0
Glucose0.50.91.9-1.41.0-1.31.2-1.1-0.60.50.20.1
Heart weight1.52.45.1-2.31.4-0.40.5-1.3-2.22.1-0.4-1.6
Delay discount hyperbolic model param0.40.51.60.5-0.51.3-1.1-0.10.2-0.00.2-0.8
Intermittent access intake day 1-15 change0.40.81.40.00.1-0.80.81.11.2-1.10.71.0
Intermittent access intake escalation0.51.11.90.2-0.2-0.90.91.21.4-1.30.91.3
Intermittent access intake escalation 20.30.30.90.5-0.40.10.11.00.9-0.70.30.3
Intermitt. access day 1 inactive lever presses0.41.74.31.8-1.20.4-0.62.11.7-1.4-0.00.8
Intermitt. access day 15 inactive lever presses0.10.20.40.6-0.60.4-0.50.60.2-0.40.40.5
Intermitt. access escalation Index0.30.51.9-0.2-0.0-1.10.60.10.3-0.70.11.4
Intermittent access day 1 total infusions0.40.61.1-1.10.5-0.80.8-0.9-0.90.80.3-0.1
Intermittent access day 15 total infusions0.81.23.0-0.90.3-1.71.70.10.3-0.51.51.3
Intermittent access terminal intake (last 3 days)0.40.52.4-0.60.1-0.91.00.20.3-0.31.60.4
Intermittent access total infusions0.50.53.3-0.80.0-0.70.70.10.0-0.11.80.1
Intermittent access day 1 locomotion0.40.51.00.2-0.6-0.90.80.70.6-0.70.91.0
Intermittent access day 15 total locomotion0.40.71.3-0.1-0.2-1.21.20.30.9-0.81.10.9
Intermittent access total locomotion0.91.14.00.4-0.9-0.60.50.91.2-1.12.00.6
Intermittent access standard deviation0.40.82.30.5-0.61.5-1.30.90.3-0.21.0-0.9
Left kidney weight0.83.911.01.0-1.53.3-3.21.4-0.3-0.01.5-2.5
Right kidney weight0.94.213.20.7-1.03.6-3.50.7-0.60.61.0-2.9
Cocaine induced anxiety0.40.51.21.1-0.7-0.10.01.00.8-0.8-0.60.6
Post-drug Anxiety0.20.20.6-0.3-0.0-0.80.8-0.3-0.3-0.10.30.7
Baseline Anxiety1.82.14.9-2.11.2-0.91.0-2.2-1.91.40.9-0.1
Tail length1.04.17.72.0-2.42.8-2.42.51.1-1.01.7-1.6
Length with tail1.04.311.61.8-2.23.4-2.81.90.7-0.71.7-1.7
Length without tail0.51.54.31.3-1.42.1-1.71.00.4-0.81.1-0.2
Times rat made contact with spout0.10.10.4-0.20.00.7-0.5-0.3-0.20.10.6-0.3
Lifetime Intake0.20.31.3-0.80.2-0.40.4-0.3-0.40.21.2-0.2
Liver weight, left2.44.08.91.8-2.62.0-1.92.01.5-1.73.0-0.6
Liver weight, right2.64.69.31.7-2.42.4-2.22.31.7-1.83.1-1.0
Locomotor activity0.91.52.5-1.61.5-0.60.5-1.5-1.61.5-0.8-0.5
Locomotor testing distance1.93.58.0-1.91.40.6-0.7-2.0-2.82.7-0.8-2.1
Locomotor testing rearing1.73.48.8-1.81.01.0-0.9-1.8-2.52.60.0-3.0
Locomotion in novel chamber0.50.61.70.10.1-0.90.80.10.9-1.00.71.3
Locomotion in novel chamber post-restriction3.45.611.8-3.02.8-3.43.1-2.7-1.31.3-0.51.0
Fecal boli incidents, locomotor time 10.30.40.90.3-0.40.8-0.70.1-0.60.6-0.9-0.9
Change in fecal boli incidents, locomotor task0.60.62.1-0.50.1-0.50.70.00.4-0.71.41.1
Time >=10cm from walls, locomotor time 10.40.41.8-0.10.0-0.81.00.0-0.2-0.1-0.31.3
Bouts of movement, locomotor time 11.11.22.5-1.11.2-1.10.8-0.9-1.21.2-1.6-0.3
Total resting periods, locomotor time 11.11.22.3-1.21.3-1.51.2-0.8-0.90.9-1.40.2
Rest time, locomotor task time 10.60.71.9-0.70.7-1.20.9-1.4-0.80.4-0.20.8
Distance moved, locomotor task time 10.50.81.80.8-0.81.3-1.20.50.6-0.30.6-1.2
Vertical activity count, locomotor time 10.51.12.90.6-0.81.6-1.40.50.30.01.0-1.7
Time >=10cm from walls, locomotor time 20.30.41.20.7-0.51.1-0.80.7-0.00.0-0.4-0.4
Bouts of movement, locomotor time 20.71.14.6-0.30.80.0-0.1-0.8-1.21.3-2.2-0.8
Total resting periods, locomotor time 20.50.93.9-0.20.6-0.1-0.1-0.7-1.01.2-2.0-0.7
Rest time, locomotor task time 20.10.10.40.6-0.20.0-0.3-0.0-0.1-0.1-0.60.6
Distance moved, locomotor task time 20.91.12.80.6-1.01.7-1.50.40.2-0.00.8-1.5
Vertical activity count, locomotor time 21.82.55.01.1-1.72.2-2.11.10.4-0.41.8-1.9
Light reinforcement 10.20.51.1-0.40.50.5-0.6-0.4-0.91.0-1.0-0.9
Light reinforcement 20.10.20.50.4-0.2-0.30.30.40.6-0.50.10.7
Bone: marrow area0.30.71.61.3-1.11.2-1.20.10.2-0.10.2-0.8
Bone: maximum diameter0.30.61.40.6-0.81.2-1.1-0.2-0.40.40.1-1.1
Bone: maximum force0.30.51.40.00.3-0.90.9-0.90.1-0.1-0.61.2
Bone: maximum moment0.20.41.4-0.00.3-0.80.9-0.70.2-0.2-0.41.2
Mean time between licks in bursts0.51.24.8-0.2-0.21.3-1.5-0.3-1.00.80.6-2.2
Mean num. licks in bursts0.30.51.0-0.91.0-0.40.5-0.6-0.90.9-0.8-0.3
Cd content in liver0.70.72.0-0.7-0.00.6-0.5-0.6-1.31.10.3-1.4
Co content in liver1.92.24.7-1.10.90.4-0.4-1.4-2.12.2-1.9-1.8
Cu content in liver1.01.23.01.3-1.01.7-1.60.8-0.30.2-0.4-1.2
Fe content in liver0.20.20.50.7-0.50.5-0.30.60.6-0.4-0.30.1
K content in liver1.11.13.92.0-0.90.9-1.00.50.8-0.8-1.00.6
Mg content in liver0.70.72.21.5-0.41.1-1.10.30.0-0.2-1.30.1
Mn content in liver0.60.62.21.2-0.50.10.00.10.4-0.5-1.51.1
Na content in liver1.71.95.02.2-1.50.8-0.61.11.8-1.7-0.11.2
Rb content in liver0.20.30.60.4-0.1-0.70.70.00.2-0.2-0.70.7
Se content in liver2.02.46.12.5-1.81.2-1.02.11.5-1.6-0.31.0
Sr content in liver0.30.30.8-0.50.7-0.20.1-0.5-0.50.6-0.9-0.2
Zn content in liver2.42.75.4-0.40.91.6-1.6-0.8-2.02.1-2.0-2.3
Bone: minimum diameter1.83.45.12.2-2.22.2-2.21.71.4-1.41.7-0.8
Time in familiar zone, hab. session 10.10.10.3-0.40.3-0.40.40.20.4-0.30.60.2
Time in novel zone, hab. session 10.80.81.9-0.50.4-0.0-0.1-1.1-1.41.3-1.2-0.7
Total zone transitions, hab. session 10.71.02.3-0.61.0-0.80.9-1.5-0.90.9-1.40.5
Total locomotion distance, hab. session 13.04.311.32.3-2.13.4-3.31.60.7-0.50.4-1.8
Locomotion velocity, hab. session 13.95.512.92.7-2.43.6-3.52.21.2-1.00.8-1.6
Time in familiar zone, hab. session 20.70.81.7-1.30.9-0.80.9-0.3-1.01.0-0.6-0.6
Time in novel zone, hab. session 20.60.61.61.0-0.81.1-1.30.30.4-0.40.4-0.4
Total zone transitions, hab. session 20.60.82.2-0.61.2-0.50.5-1.2-0.80.9-1.50.0
Total locomotion distance, hab. session 23.14.010.82.1-1.73.2-3.31.70.6-0.50.4-1.8
Locomotion velocity, hab. session 22.83.810.82.1-1.53.3-3.31.50.4-0.2-0.1-1.9
Novel to familiar place preference ratio0.20.20.50.7-0.5-0.10.10.20.7-0.60.00.7
Novelty place preference0.10.10.20.5-0.2-0.20.1-0.10.4-0.3-0.20.5
Time in novel zone, NPP test0.10.10.30.00.2-0.50.4-0.50.00.0-0.40.4
Total zone transitions, NPP test0.81.22.1-1.21.5-1.41.3-1.4-0.70.6-0.90.6
Total locomotion distance, NPP test2.23.07.91.8-1.62.7-2.81.61.0-0.70.7-1.4
Locomotion velocity, NPP test2.73.89.12.2-1.93.0-3.01.91.2-1.00.8-1.3
Intraocular pressure2.13.05.8-2.41.8-2.12.2-1.9-1.61.5-0.40.2
Delta distance traveled before/after self-admin0.10.10.50.4-0.10.2-0.10.40.7-0.3-0.50.1
Delta ambulatory time before/after self-admin0.10.10.30.10.10.10.10.40.6-0.1-0.6-0.1
Parametrial fat weight0.61.53.50.6-0.91.9-1.61.10.5-0.41.7-1.2
Pavlov. Cond. lever latency0.10.10.30.2-0.30.4-0.50.4-0.10.2-0.4-0.5
Pavlov. Cond. magazine entry latency0.70.91.8-1.11.10.1-0.1-1.1-1.21.3-0.5-1.2
Pavlov. Cond. change in total contacts0.70.72.80.4-0.80.3-0.20.51.0-1.11.70.5
Pavlov. Cond. index score0.30.40.9-0.70.70.1-0.0-0.9-0.70.8-0.1-0.6
Pavlov. Cond. latency score0.10.10.3-0.30.30.2-0.0-0.6-0.30.40.2-0.3
Pavlov. Cond. lever contacts0.00.00.1-0.00.10.3-0.2-0.3-0.00.10.2-0.2
Pavlov. Cond. magazine entry number1.11.32.81.4-1.20.2-0.21.71.4-1.50.41.1
Pavlov. Cond. intertrial magazine entries1.92.34.11.7-1.70.5-0.61.82.0-2.01.41.0
Pavlov. Cond. lever-magazine prob. diff.0.20.30.8-0.70.7-0.10.2-0.9-0.50.6-0.0-0.3
Pavlov. Cond. response bias0.20.30.8-0.70.70.1-0.1-0.9-0.60.7-0.1-0.6
Pavlov. Cond. lever latency14.720.031.35.3-5.63.4-3.35.45.0-4.84.31.2
Pavlov. Cond. magazine entry latency4.35.210.8-3.33.0-1.81.8-2.3-2.62.4-1.5-0.8
Pavlov. Cond. change in total contacts7.411.818.9-4.24.2-1.91.8-3.8-4.34.1-3.1-2.1
Pavlov. Cond. index score10.213.821.9-4.64.7-2.62.5-4.1-4.44.1-3.4-1.4
Pavlov. Cond. latency score8.911.819.4-4.44.4-2.62.5-3.8-3.93.7-3.1-1.1
Pavlov. Cond. lever contacts13.819.129.6-5.35.4-3.33.2-5.2-5.04.8-4.1-1.4
Pavlov. Cond. magazine entry number8.710.719.44.4-4.12.7-2.73.53.8-3.52.40.9
Pavlov. Cond. intertrial magazine entries2.13.17.12.4-1.92.6-2.71.30.9-0.80.6-1.3
Pavlov. Cond. lever-magazine prob. diff.9.512.620.1-4.54.5-2.52.4-4.0-4.24.0-3.2-1.4
Pavlov. Cond. response bias15.020.330.7-5.45.5-3.13.0-5.3-5.35.1-4.2-1.8
Time in closed arm before self-admin0.00.10.1-0.20.30.3-0.1-0.1-0.10.3-0.4-0.0
Time in closed arm after self-admin0.20.20.5-0.50.40.2-0.2-0.2-0.70.5-0.4-0.4
Time in open arm before self-admin0.50.52.00.00.20.4-0.6-0.3-0.90.8-1.4-0.7
Time in open arm after self-admin0.00.00.10.3-0.1-0.1-0.0-0.10.2-0.2-0.10.0
Bone: periosteal estimation0.61.22.31.5-1.51.5-1.50.60.5-0.50.6-0.7
Bone: periosteal perimeter0.20.30.80.4-0.50.8-0.8-0.3-0.30.4-0.0-0.9
Bone: post-yield work0.50.72.50.6-0.3-0.50.50.31.2-1.20.11.6
Progressive ratio test 1 active lever presses0.20.30.70.1-0.3-0.40.50.60.4-0.60.80.8
Progressive ratio test 1 breakpoint0.30.30.80.1-0.3-0.50.50.60.4-0.60.80.9
Progressive ratio test 1 inactive lever presses0.20.31.10.2-0.4-0.50.50.80.2-0.60.21.1
Progressive ratio test 2 active lever presses0.30.42.2-0.4-0.0-0.60.50.30.3-0.21.5-0.2
Progressive ratio test 2 breakpoint0.30.42.1-0.4-0.0-0.60.50.30.3-0.21.4-0.2
Progressive ratio test 2 inactive lever presses0.20.31.0-1.00.6-0.50.7-0.3-0.50.40.60.0
Incentive Sensitization - Responses0.10.20.6-0.60.2-0.20.1-0.0-0.40.20.8-0.6
Incentive Sensitization - Breakpoint0.10.20.5-0.60.3-0.30.1-0.0-0.30.20.7-0.6
Sum of active levers in priming session hrs 5-60.10.10.20.00.2-0.3-0.10.20.3-0.40.10.1
Progressive ratio1.01.65.3-0.61.20.6-0.4-1.0-1.11.5-2.3-1.4
Food seeking constrained by brief footshock2.02.55.6-1.21.00.6-0.9-1.5-2.22.1-1.3-2.4
Seeking ratio, punishment vs. effort1.01.54.01.0-1.61.1-1.31.20.7-1.02.0-0.6
Retroperitoneal fat weight2.811.825.61.5-3.14.8-4.72.70.7-0.85.1-4.0
Reaction time number correct0.10.21.2-0.20.6-0.40.2-0.3-0.40.2-1.10.3
Reaction time mean minus median0.61.42.6-1.11.10.6-0.7-1.1-1.61.6-0.8-1.6
Reaction time mean minus median AUC0.30.71.3-0.80.70.5-0.5-1.0-1.11.1-0.5-1.0
Reaction time num false alarms3.65.07.42.7-2.72.6-2.32.52.1-2.01.8-0.3
Reaction time num false alarms AUC2.84.46.32.4-2.52.3-2.02.42.1-2.02.1-0.1
Reaction time trials correct on left0.10.21.2-0.20.6-0.40.2-0.3-0.40.2-1.10.3
Reaction time trials on left0.10.31.3-0.30.6-0.40.2-0.4-0.40.2-1.10.3
Reaction time mean0.40.61.20.10.21.1-0.8-1.0-0.50.7-0.7-1.0
Reaction time mean AUC0.20.41.10.3-0.11.1-0.7-0.8-0.20.4-0.3-0.6
Median of all reaction times0.30.41.00.5-0.01.0-0.7-1.0-0.00.3-0.6-0.5
Reaction time omissions0.50.72.0-0.70.50.9-0.9-0.8-0.90.9-0.0-1.4
Reaction time false alarm rate2.83.85.32.1-2.31.9-1.72.22.0-1.92.2-0.0
Reaction time premature initiation rate0.40.52.4-0.20.00.7-1.00.3-0.20.60.2-1.6
Reaction time premature initiations0.20.41.6-0.60.40.4-0.8-0.1-0.60.7-0.2-1.3
Std. dev. reaction times0.91.74.3-0.60.51.3-1.3-1.2-1.51.6-0.7-2.1
Reaction time trials completed0.10.31.3-0.30.6-0.40.2-0.4-0.40.2-1.10.3
Reaction time trials AUC0.10.21.3-0.30.5-0.20.0-0.4-0.50.3-1.10.0
Run reversals in cocaine runway, females2.02.06.21.4-0.72.0-2.50.80.6-0.1-0.2-2.2
Run reversals in cocaine runway, males4.04.09.0-2.82.2-1.81.9-3.0-2.11.7-0.00.1
Latency to leave start box in cocaine runway2.12.35.72.4-1.71.6-1.71.61.4-1.3-0.70.5
Latency to leave start box in cocaine runway, F2.12.45.72.4-1.51.9-2.11.31.3-0.9-1.3-0.1
Latency to leave start box in cocaine runway, M0.60.61.41.0-0.90.6-0.51.20.6-0.90.30.7
Std. dev. time between licks in bursts0.50.71.50.6-0.91.1-1.20.90.2-0.41.0-0.7
Total sessions with >9 infusions0.50.61.4-0.20.30.8-0.9-0.2-1.00.9-0.9-1.2
Short access day 1 total inactive lever presses0.30.31.20.4-0.60.1-0.20.60.4-0.71.10.4
Short access day 10 total inactive lever presses0.00.10.20.3-0.2-0.10.1-0.00.3-0.1-0.10.4
Short access day 1 total infusions0.50.71.9-0.60.20.6-0.8-0.6-1.10.80.4-1.4
Short access day 10 total infusions0.40.51.3-0.30.00.8-0.8-0.4-1.10.9-0.3-1.0
Short access total infusions0.50.61.6-0.60.30.6-0.7-0.6-1.21.0-0.4-1.1
Short access day 1 locomotion0.40.51.1-0.70.6-0.50.5-0.9-1.00.8-0.80.1
Short access day 10 total locomotion0.00.10.10.1-0.10.1-0.10.20.4-0.20.2-0.3
Short access total locomotion0.20.20.70.6-0.50.4-0.40.80.4-0.3-0.4-0.3
One hour access (0.3 mA shock)0.70.81.7-1.31.0-1.10.9-0.8-0.80.90.2-0.4
Compulsive drug intake0.91.02.61.2-0.5-0.1-0.01.11.6-1.40.21.3
One hour access (shock baseline)1.31.93.9-2.01.6-1.71.7-1.3-1.31.2-0.20.0
Social response proportion0.50.51.30.8-0.51.2-0.81.00.8-0.50.2-0.3
Social responses0.40.51.1-0.90.70.5-0.1-0.3-0.91.0-0.4-1.1
Social time1.62.23.51.9-1.61.8-1.81.91.3-1.20.6-0.5
Soleus weight0.92.76.91.1-1.42.6-2.51.70.20.00.8-2.0
Bone: stiffness0.30.52.00.5-0.3-0.70.8-0.30.7-0.80.31.4
Tibialis anterior weight0.20.61.9-0.20.40.9-0.9-0.5-0.70.8-0.5-1.4
Time to tail flick, vehicle, before self-admin0.50.51.7-0.90.8-1.31.0-0.4-0.20.4-0.40.1
Time to tail flick, vehicle, after self-admin1.41.84.0-1.71.4-0.50.7-1.4-2.01.9-0.9-0.8
Time to tail flick, test, before self-admin0.50.51.60.5-0.81.2-1.30.1-0.60.30.2-0.7
Time to tail flick, test, after self-admin2.22.37.50.4-0.31.9-2.10.1-1.21.3-1.3-2.7
Delta time to tail flick, vehicle, before/after SA0.70.61.4-0.80.90.10.3-0.6-1.21.1-1.0-0.4
Delta time to tail flick, test, before/after SA0.30.30.70.5-0.00.5-0.50.80.5-0.1-0.9-0.8
Tibia length0.10.41.31.0-0.40.7-0.70.3-0.30.2-1.1-0.1
Ambulatory time before self-admin0.20.30.70.5-0.30.1-0.10.50.5-0.80.70.9
Ambulatory time after self-admin0.70.81.81.0-0.50.4-0.31.21.3-1.2-0.11.0
Bone: tissue strength2.42.55.20.4-0.6-0.91.00.82.1-2.32.22.3
Total heroin consumption0.70.82.1-1.51.3-0.50.4-0.7-1.10.9-0.7-0.2
Bone: trabecular number0.91.64.20.6-0.5-1.11.01.01.6-1.60.72.1
Bone: trabecular spacing0.30.40.8-0.60.70.4-0.3-0.6-0.90.9-0.5-0.8
Bone: trabecular thickness0.10.10.50.1-0.6-0.0-0.1-0.1-0.1-0.00.7-0.3
Bone: trabecular tissue density0.20.30.50.7-0.60.7-0.5-0.1-0.40.2-0.5-0.5
Water consumed over 24 hours0.20.30.80.0-0.2-0.30.20.30.6-0.70.80.9
Number of responses in last shaping day0.70.81.80.7-1.11.4-1.10.4-0.60.60.5-1.3