Hub : Genes

Gdpd5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio NM_001109152.2 0.04 0.04 2.6e-03 0.04 0.02 0.03 0.03 3.1e-04 4.8e-03 2.1e-03 1.1e-03
2 NAcc isoform ratio XM_006229817.4 0.02 0.02 7.6e-03 0.01 0.01 0.01 0.01 3.1e-02 1.8e-02 3.1e-02 3.7e-02
3 Adipose gene expression Gdpd5 0.07 0.05 1.2e-07 0.04 0.05 0.06 0.05 7.9e-05 1.2e-06 1.9e-07 1.3e-06
4 pVTA gene expression Gdpd5 0.11 0.08 3.1e-03 0.03 0.02 0.03 0.01 2.0e-02 5.0e-02 2.0e-02 7.7e-02
5 NAcc intron excision ratio chr1_153756067_153758421 0.03 0.03 1.2e-03 0 0.02 0.01 0.01 1.2e-01 3.5e-03 1.2e-02 3.0e-02
6 Brain gene expression Gdpd5 0.41 0.16 0.0e+00 0.24 0.27 0.27 0.27 5.5e-22 8.4e-25 1.8e-25 1.4e-25
7 NAcc intron excision ratio chr1_153756541_153758421 0.03 0.02 2.2e-03 0.01 0.02 0.01 0.01 4.5e-02 3.7e-03 5.2e-02 2.2e-02
8 PL intron excision ratio chr1_153756067_153756527 0.02 0.02 4.7e-03 0.01 0.01 0 0.01 1.4e-02 1.2e-02 3.0e-01 5.0e-02
9 NAcc gene expression Gdpd5 0.08 0.05 3.0e-09 0.07 0.07 0.07 0.07 1.1e-08 5.2e-09 1.6e-08 5.2e-09
10 Brain isoform ratio XM_017590191.2 0.15 0.12 1.4e-06 0.07 0.06 0.05 0.06 9.7e-07 2.8e-06 1.2e-05 6.1e-06
11 PL intron excision ratio chr1_153756067_153758421 0.03 0.03 6.7e-04 0.03 0.03 0.01 0.02 6.7e-04 8.3e-04 7.6e-03 2.6e-03
12 BLA gene expression Gdpd5 0.16 0.13 6.7e-05 0.08 0.07 0.07 0.07 5.6e-05 1.3e-04 1.3e-04 1.1e-04
13 Brain mRNA stability Gdpd5 0.05 0.04 6.5e-04 0.04 0.04 0.03 0.04 2.3e-04 1.7e-04 4.9e-04 2.5e-04
14 Brain intron excision ratio chr1_153680398_153723199 0.11 0.1 3.4e-05 0.05 0.05 0.04 0.05 1.2e-05 3.4e-05 4.7e-05 3.0e-05
15 IL gene expression Gdpd5 0.4 0.17 5.6e-06 0.22 0.19 0.2 0.2 6.0e-06 2.7e-05 1.7e-05 1.4e-05
16 Eye gene expression Gdpd5 0.73 0.14 3.3e-06 0.22 0.19 0.19 0.18 2.4e-04 7.6e-04 6.7e-04 9.6e-04
17 Eye isoform ratio XM_006229814.4 0.36 0.18 6.6e-03 0.12 0.06 0.03 0.06 7.4e-03 4.6e-02 1.1e-01 3.8e-02
18 NAcc intron excision ratio chr1_153680398_153723199 0.05 0.03 1.9e-06 0.05 0.05 0.04 0.05 1.9e-06 3.6e-06 7.5e-06 4.2e-06
19 NAcc isoform ratio XM_017590191.2 0.08 0.06 2.7e-06 0.06 0.04 0.05 0.05 5.6e-07 3.0e-05 2.6e-06 3.9e-06
20 PL gene expression Gdpd5 0.3 0.13 0.0e+00 0.14 0.18 0.17 0.17 1.3e-15 2.7e-19 7.6e-18 6.9e-19

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.20.40.7-0.50.30.70.40.5-0.7-0.3-0.2-0.60.9-0.90.90.20.9-0.6-0.5-0.50.50.5-0.6
Area under the delay curve0.10.10.30.1-0.2-0.3-0.4-0.30.40.30.20.2-0.50.5-0.50.2-0.5-0.10.20.2-0.2-0.20.4
BMI with tail0.10.30.5-0.0-0.2-0.3-0.6-0.40.40.50.50.4-0.60.6-0.60.7-0.6-0.50.60.6-0.6-0.60.7
BMI without tail2.95.99.11.2-2.0-2.0-1.3-2.42.42.62.72.6-2.62.6-2.52.3-2.4-3.02.62.6-2.6-2.72.6
Body weight1.77.39.91.2-1.9-2.3-1.8-2.52.62.72.72.5-3.13.1-3.12.5-3.1-2.93.03.0-3.0-2.93.0
Weight adjusted by age1.82.02.51.1-1.4-1.5-0.3-1.51.51.61.51.6-1.41.4-1.50.8-1.5-1.61.61.6-1.6-1.61.3
Bone surface0.50.92.91.3-1.5-1.01.0-1.20.91.31.31.0-0.40.4-0.4-0.1-0.4-1.70.70.7-0.7-0.7-0.1
Bone volume0.30.52.40.9-1.1-0.70.8-0.90.61.01.00.7-0.20.2-0.20.1-0.2-1.60.50.5-0.5-0.5-0.0
Breakpoint value in progressive ratio session0.20.20.5-0.50.70.60.20.7-0.4-0.7-0.7-0.40.4-0.40.5-0.20.40.7-0.4-0.40.40.2-0.4
Number of licking bursts1.21.56.5-2.51.91.6-2.51.3-1.2-1.0-0.9-1.00.2-0.20.21.90.20.2-0.1-0.10.10.11.0
Context. condit. distance diff. score0.60.84.01.4-1.2-0.72.0-0.60.30.40.40.20.4-0.40.4-1.80.40.1-0.4-0.40.40.5-1.4
Locomotion velocity, session 11.11.22.4-0.51.10.90.41.2-1.0-1.3-1.4-1.01.2-1.21.2-0.81.21.6-1.1-1.11.11.1-0.9
Locomotion distance, session 10.40.52.20.9-0.1-0.31.30.10.1-0.4-0.6-0.10.5-0.50.5-1.50.51.2-0.5-0.50.50.5-0.9
Locomotion velocity, session 20.10.10.10.4-0.1-0.40.1-0.20.40.10.00.3-0.30.3-0.30.0-0.30.30.30.3-0.3-0.30.4
Locomotion distance, session 20.10.10.90.8-0.3-0.40.9-0.10.3-0.0-0.10.20.1-0.10.1-0.70.10.5-0.1-0.10.10.1-0.3
Locomotion velocity, session 30.50.62.10.6-0.00.01.40.3-0.2-0.5-0.6-0.30.8-0.80.8-1.40.81.0-0.6-0.60.60.7-1.2
Locomotion distance, session 30.91.03.40.8-0.1-0.01.80.3-0.3-0.6-0.7-0.51.0-1.01.0-1.81.01.2-0.9-0.90.91.0-1.4
Stereotopy head waving bouts, day 30.30.41.1-0.30.0-0.2-1.0-0.20.30.40.40.3-0.60.6-0.71.1-0.6-0.60.60.6-0.6-0.61.0
Stereotopy head waving duration, day 30.10.10.20.3-0.2-0.10.4-0.1-0.00.00.0-0.00.3-0.30.2-0.50.30.0-0.3-0.30.30.3-0.5
Locomotion velocity, session 70.30.40.5-0.60.70.7-0.10.7-0.6-0.7-0.7-0.70.6-0.60.6-0.30.60.6-0.5-0.50.50.5-0.6
Locomotion distance, session 70.00.00.2-0.30.20.2-0.40.1-0.0-0.1-0.0-0.1-0.10.1-0.10.2-0.1-0.00.10.1-0.1-0.00.0
Stereotopy head waving bouts, day 70.50.53.61.4-0.9-0.91.9-0.60.50.30.20.30.1-0.10.1-1.40.10.4-0.3-0.30.30.1-0.7
Stereotopy head waving duration, day 70.70.93.61.8-1.4-1.31.9-1.11.00.90.80.9-0.30.3-0.3-1.2-0.3-0.20.20.2-0.2-0.4-0.4
Locomotion velocity, session 80.30.31.11.0-1.0-0.61.0-0.70.50.60.60.6-0.00.0-0.0-0.7-0.0-0.50.20.2-0.2-0.1-0.6
Locomotion distance, session 80.50.83.91.8-1.2-1.12.0-0.80.80.50.40.50.0-0.0-0.0-1.70.00.3-0.0-0.00.00.1-0.9
Degree of sensitization distance2.42.44.4-0.2-0.6-0.7-1.9-1.01.11.31.41.2-1.71.7-1.82.1-1.7-1.81.71.7-1.7-1.72.0
Degree of sensitization stereotypy1.11.27.22.2-1.5-1.42.7-1.00.90.60.40.60.0-0.00.0-2.00.00.5-0.2-0.20.20.1-0.9
Conditioned locomotion0.30.40.6-0.30.40.60.20.5-0.6-0.6-0.6-0.60.7-0.70.7-0.50.70.6-0.7-0.70.70.7-0.7
Cocaine response after cond. corrected0.60.63.3-1.30.90.5-1.80.5-0.1-0.3-0.30.0-0.50.5-0.51.4-0.50.10.60.6-0.6-0.61.1
Cocaine response after cond. not corrected0.20.20.8-0.80.70.4-0.90.4-0.1-0.4-0.4-0.1-0.20.2-0.20.6-0.20.50.30.3-0.3-0.30.5
Cocaine response before conditioning0.50.63.91.1-0.5-0.32.0-0.1-0.0-0.1-0.2-0.10.7-0.70.7-1.50.70.4-0.6-0.60.60.6-1.2
Saline control response1.62.13.71.9-1.8-1.80.7-1.71.81.61.51.7-1.31.3-1.30.0-1.3-1.21.51.5-1.5-1.40.8
Bone: connectivity density0.30.51.3-0.1-0.00.60.90.4-0.6-0.3-0.2-0.61.1-1.11.0-0.51.1-0.5-0.8-0.80.80.7-1.1
Bone: cortical apparent density0.40.63.1-1.30.70.5-1.80.4-0.1-0.10.00.1-0.40.4-0.41.6-0.4-0.70.50.5-0.5-0.51.0
Bone: cortical area0.71.02.10.9-1.2-1.00.2-1.11.11.21.31.2-0.90.9-0.90.4-0.9-1.51.01.0-1.0-1.10.5
Bone: cortical porosity0.50.52.40.8-0.3-0.21.50.1-0.1-0.3-0.4-0.30.5-0.50.5-1.60.51.0-0.6-0.60.60.6-1.1
Bone: cortical porosity0.50.62.10.6-0.1-0.01.40.2-0.2-0.4-0.5-0.40.7-0.70.7-1.50.71.1-0.7-0.70.70.7-1.1
Bone: cortical thickness0.10.10.3-0.50.40.5-0.10.5-0.4-0.4-0.3-0.20.4-0.40.40.20.4-0.1-0.2-0.20.20.2-0.2
Bone: cortical thickness0.10.10.60.30.0-0.00.80.1-0.0-0.3-0.3-0.10.4-0.40.4-0.70.40.5-0.1-0.10.10.1-0.6
Bone: cortical tissue density0.40.53.0-1.30.80.6-1.70.4-0.2-0.1-0.00.0-0.30.3-0.41.6-0.3-0.60.40.4-0.4-0.40.9
Condit. Reinf. active minus inactive responses0.80.91.50.7-0.9-0.9-0.3-1.00.91.01.11.0-0.90.9-0.90.7-0.9-1.21.01.0-1.0-1.10.8
Condit. Reinf. active-inactive response ratio1.51.63.41.0-1.4-1.2-0.1-1.41.31.51.61.5-1.21.2-1.20.8-1.2-1.81.31.3-1.3-1.40.9
Condit. Reinf. active responses0.20.20.30.3-0.3-0.4-0.4-0.40.40.50.50.5-0.50.5-0.50.5-0.5-0.60.50.5-0.5-0.60.6
Condit. Reinf. inactive responses0.10.20.5-0.20.50.3-0.00.5-0.4-0.5-0.6-0.50.3-0.30.3-0.20.30.7-0.4-0.40.40.4-0.1
Incentive salience index mean0.60.71.00.8-0.9-0.9-0.1-0.90.91.00.91.0-0.90.9-0.90.5-0.9-1.00.90.9-0.9-1.00.7
Condit. Reinf. lever presses0.10.20.40.6-0.5-0.60.1-0.50.50.40.40.4-0.40.4-0.40.0-0.4-0.30.30.3-0.3-0.40.3
Condit. Reinf. active minus inactive responses4.65.712.03.5-3.2-3.31.6-3.02.92.62.52.8-2.22.2-2.2-0.7-2.2-1.52.12.1-2.1-2.10.9
Condit. Reinf. active-inactive response ratio0.60.72.11.4-1.1-1.31.0-1.01.10.80.60.9-0.70.7-0.7-0.7-0.70.00.50.5-0.5-0.50.1
Condit. Reinf. active responses7.410.218.14.3-4.1-4.21.7-3.93.83.63.43.7-3.03.0-3.0-0.3-3.0-2.53.03.0-3.0-3.01.4
Condit. Reinf. inactive responses5.66.910.23.1-3.2-3.21.0-3.13.13.02.93.0-2.52.5-2.50.4-2.5-2.52.62.6-2.6-2.61.5
Condit. Reinf. lever presses8.211.128.95.4-5.0-4.63.4-4.33.93.83.63.7-2.62.6-2.6-2.0-2.6-2.22.42.4-2.4-2.40.1
Condit. Reinf. lever reinforcers received7.310.220.14.5-4.2-4.32.1-3.93.93.63.43.7-2.92.9-2.9-0.7-2.9-2.32.92.9-2.9-2.91.2
Conditioned reinforcement - actives0.80.84.81.2-0.6-0.42.2-0.20.1-0.1-0.2-0.30.5-0.50.5-1.80.50.7-0.8-0.80.80.9-1.3
Conditioned reinforcement - inactives0.10.20.5-0.70.70.5-0.70.4-0.3-0.4-0.3-0.40.0-0.0-0.00.60.00.2-0.1-0.10.10.20.5
Conditioned locomotion1.21.46.00.7-0.10.12.40.4-0.4-0.7-0.8-0.71.2-1.21.1-2.01.21.2-1.1-1.11.11.2-1.8
Patch foraging indifference point 0 sec2.13.39.33.0-2.9-2.62.1-2.42.22.12.01.9-1.31.3-1.2-1.5-1.2-1.31.11.1-1.1-1.0-0.4
Patch foraging indifference point AUC0.80.91.40.4-0.8-0.9-0.6-1.00.91.01.11.0-1.11.1-1.20.9-1.1-0.90.90.9-0.9-1.01.1
Delay disc. indifference point, 0s delay0.60.61.41.1-0.9-1.20.5-0.91.20.70.60.9-0.80.7-0.8-0.3-0.8-0.10.80.8-0.8-0.80.3
Delay disc. indifference point, 16s delay0.10.20.4-0.40.40.40.10.4-0.3-0.4-0.4-0.60.3-0.30.4-0.20.30.4-0.5-0.50.50.5-0.2
Delay disc. indifference point, 2s delay1.01.22.11.3-1.2-1.4-0.2-1.31.41.11.01.0-1.41.4-1.3-0.2-1.4-0.20.90.9-0.9-0.60.8
Delay disc. indifference point, 24s delay0.40.41.2-1.10.91.0-0.50.7-0.8-0.6-0.5-0.50.4-0.40.30.70.4-0.2-0.6-0.60.60.00.1
Delay disc. indifference point, 4s delay1.41.52.51.3-1.0-1.5-0.2-1.21.61.10.91.4-1.51.5-1.50.3-1.5-0.21.31.3-1.3-1.31.2
Delay disc. indifference point, 8s delay0.10.10.30.4-0.5-0.4-0.1-0.50.40.40.40.3-0.40.4-0.4-0.2-0.4-0.30.10.1-0.1-0.10.1
Indifference point function ln k0.91.24.30.9-0.30.12.10.2-0.3-0.5-0.6-0.51.1-1.11.2-2.11.11.0-1.1-1.11.11.1-1.8
Indifference point function log k0.91.24.30.9-0.30.12.10.2-0.3-0.5-0.6-0.51.1-1.11.2-2.11.11.0-1.1-1.11.11.1-1.8
Patch foraging total patch changes 0 sec1.72.87.62.8-2.6-2.41.8-2.22.01.91.81.7-1.21.2-1.2-1.3-1.1-1.11.01.0-1.0-0.9-0.3
Patch foraging total patch changes 12 sec2.22.94.31.7-2.1-2.10.2-2.02.02.02.01.9-1.71.7-1.70.4-1.7-1.71.61.6-1.6-1.61.0
Patch foraging total patch changes 18 sec1.92.44.41.9-2.1-2.00.9-1.91.91.91.91.7-1.51.5-1.50.0-1.4-1.61.31.3-1.3-1.30.6
Patch foraging total patch changes 24 sec0.81.01.91.1-1.1-1.40.0-1.21.21.11.01.0-1.21.2-1.20.2-1.1-0.50.80.8-0.8-0.80.9
Patch foraging total patch changes 6 sec0.30.41.41.2-1.1-0.81.1-0.80.60.70.70.4-0.10.1-0.1-0.9-0.1-0.4-0.1-0.10.10.0-0.6
Patch foraging time to switch 0 sec2.23.37.5-2.72.72.4-1.62.4-2.1-2.2-2.1-2.11.5-1.51.50.71.51.5-1.4-1.41.41.4-0.3
Patch foraging water rate 0 sec1.22.05.92.4-2.1-2.01.9-1.81.71.51.41.5-0.90.9-1.0-1.3-0.9-0.80.90.9-0.9-0.9-0.3
Patch foraging water rate 12 sec0.50.73.91.7-1.2-0.92.0-0.80.70.50.50.50.2-0.20.1-1.50.10.0-0.1-0.10.10.2-0.9
Patch foraging water rate 18 sec0.40.61.61.3-1.1-1.00.8-1.01.00.80.80.8-0.50.5-0.7-0.3-0.7-0.50.60.6-0.6-0.50.2
Patch foraging water rate 24 sec0.81.24.70.8-0.20.12.20.3-0.4-0.5-0.6-0.61.1-1.11.1-1.91.11.1-1.0-1.01.01.1-1.6
Patch foraging water rate 6 sec0.30.42.50.8-0.5-0.21.6-0.10.0-0.0-0.1-0.00.6-0.60.5-1.20.50.4-0.5-0.50.50.4-1.0
Seeking ratio, delayed vs. immediate footshock1.21.42.9-1.51.71.6-0.51.6-1.2-1.5-1.5-1.01.3-1.41.40.21.41.0-0.8-0.80.80.5-0.5
Distance traveled before self-admin0.20.20.8-0.80.50.6-0.90.4-0.6-0.3-0.2-0.20.3-0.30.30.60.3-0.1-0.2-0.20.20.00.2
Distance traveled after self-admin2.22.53.7-1.61.81.70.41.9-1.8-1.9-1.9-1.81.7-1.71.6-0.51.71.4-1.5-1.51.51.5-1.3
Extensor digitorum longus weight0.52.04.00.1-0.9-0.8-1.4-1.11.11.41.51.2-1.51.5-1.51.8-1.5-2.01.51.5-1.5-1.51.6
Bone: elastic displacement1.61.83.4-1.81.71.8-0.61.7-1.6-1.5-1.4-1.41.4-1.41.40.21.40.9-1.1-1.11.11.1-0.7
Bone: elastic work2.02.64.4-2.01.92.1-0.31.9-1.9-1.8-1.7-1.81.7-1.71.7-0.11.71.2-1.5-1.51.51.4-1.1
Bone: endosteal estimation2.04.45.92.0-2.4-2.30.0-2.42.32.42.42.3-2.12.1-2.10.8-2.1-2.32.22.2-2.2-2.21.6
Bone: endosteal perimeter2.24.56.92.4-2.6-2.50.4-2.62.52.52.52.3-2.02.0-2.00.4-2.0-2.12.12.1-2.1-2.01.3
Epididymis fat weight1.22.86.2-0.0-0.6-0.9-2.1-1.11.21.41.41.3-2.02.0-1.82.3-1.9-1.61.81.8-1.8-2.02.5
Delta time in closed arm before/after self-admin2.32.25.2-0.1-0.6-0.7-2.3-1.11.01.31.41.2-1.61.6-1.52.1-1.6-1.81.51.5-1.5-1.62.0
Delta time in open arm before/after self-admin1.31.32.81.7-1.6-1.51.4-1.41.31.31.21.2-0.90.9-1.0-0.5-0.9-1.00.90.9-0.9-0.80.1
Diff in mean of infusions in LGA sessions0.91.03.6-1.81.61.2-1.91.2-1.0-1.0-0.9-1.00.4-0.40.41.10.40.5-0.1-0.10.10.50.5
Delay discount exponential model param0.10.10.3-0.10.10.20.50.2-0.3-0.2-0.2-0.20.5-0.50.5-0.20.50.0-0.1-0.10.10.2-0.5
Extinction: sum of active levers before priming0.10.10.4-0.20.20.0-0.60.00.10.00.00.1-0.20.3-0.30.5-0.2-0.10.40.4-0.4-0.40.5
Active lever presses in extinction session 61.41.46.41.1-0.4-0.32.50.1-0.0-0.5-0.6-0.50.8-0.91.0-2.50.81.4-1.0-1.01.01.0-2.0
Bone: final force0.00.00.5-0.1-0.20.1-0.1-0.10.00.20.30.20.0-0.00.00.20.0-0.70.20.2-0.2-0.2-0.1
Bone: final moment0.10.10.90.2-0.5-0.20.1-0.40.20.50.60.4-0.10.1-0.10.2-0.1-1.00.30.3-0.3-0.3-0.0
Food consumed during 24 hour testing period0.80.95.22.0-1.4-1.32.3-1.00.90.70.60.90.0-0.00.0-1.30.0-0.20.10.1-0.1-0.2-0.5
Glucose0.10.10.2-0.10.30.30.40.3-0.4-0.4-0.4-0.40.4-0.40.4-0.30.40.5-0.4-0.40.40.4-0.4
Heart weight0.30.41.41.1-1.0-0.81.2-0.70.60.60.60.5-0.20.2-0.2-0.7-0.2-0.50.00.0-0.0-0.2-0.4
Delay discount hyperbolic model param0.30.30.6-0.40.40.60.50.5-0.6-0.5-0.4-0.50.8-0.80.8-0.20.80.1-0.4-0.40.40.5-0.6
Intermittent access intake day 1-15 change0.30.31.50.9-0.6-0.41.2-0.30.10.10.1-0.00.2-0.20.2-1.20.20.4-0.5-0.50.50.5-0.8
Intermittent access intake escalation0.40.42.01.0-0.7-0.51.4-0.30.20.10.10.00.3-0.30.2-1.30.30.4-0.5-0.50.50.5-0.9
Intermittent access intake escalation 20.20.20.60.8-0.7-0.60.4-0.60.50.50.50.4-0.30.3-0.4-0.4-0.3-0.20.20.2-0.2-0.1-0.1
Intermitt. access day 1 inactive lever presses0.10.20.9-0.70.60.4-0.90.4-0.3-0.3-0.3-0.3-0.00.0-0.10.70.00.1-0.0-0.00.00.00.6
Intermitt. access day 15 inactive lever presses0.30.30.6-0.20.50.50.50.6-0.5-0.6-0.7-0.50.7-0.70.6-0.50.80.6-0.5-0.50.50.4-0.6
Intermitt. access escalation Index0.10.10.30.4-0.3-0.20.6-0.20.10.20.20.20.0-0.00.0-0.10.0-0.40.10.1-0.1-0.2-0.2
Intermittent access day 1 total infusions0.50.50.80.8-0.9-0.80.7-0.80.90.80.80.9-0.50.5-0.50.1-0.5-0.90.80.8-0.8-0.80.3
Intermittent access day 15 total infusions0.30.42.41.1-0.8-0.61.5-0.50.50.40.30.40.1-0.10.1-1.00.1-0.1-0.1-0.10.10.0-0.7
Intermittent access terminal intake (last 3 days)0.30.31.51.0-0.9-0.71.2-0.70.70.60.60.6-0.20.2-0.2-0.6-0.2-0.40.20.2-0.2-0.3-0.4
Intermittent access total infusions0.20.20.70.7-0.7-0.50.8-0.50.60.50.50.5-0.20.2-0.3-0.2-0.2-0.50.30.3-0.3-0.4-0.1
Intermittent access day 1 locomotion0.20.20.4-0.20.30.40.60.4-0.3-0.4-0.4-0.30.6-0.60.5-0.40.60.3-0.3-0.30.30.3-0.6
Intermittent access day 15 total locomotion0.40.42.80.9-0.5-0.31.7-0.10.1-0.0-0.1-0.00.5-0.50.4-1.20.50.3-0.4-0.40.40.4-1.0
Intermittent access total locomotion0.10.10.70.6-0.4-0.30.9-0.30.30.20.20.30.0-0.00.0-0.40.0-0.10.00.0-0.0-0.1-0.3
Intermittent access standard deviation0.20.20.50.4-0.4-0.50.1-0.50.70.50.40.5-0.50.5-0.60.3-0.5-0.40.70.7-0.7-0.50.4
Left kidney weight2.15.97.52.3-2.5-2.7-0.4-2.72.72.72.62.5-2.72.7-2.71.1-2.7-2.42.52.5-2.5-2.32.2
Right kidney weight1.54.25.81.7-1.9-2.3-0.4-2.12.22.22.12.0-2.32.3-2.41.1-2.3-2.12.22.2-2.2-2.01.9
Cocaine induced anxiety0.60.72.3-1.51.41.2-1.11.1-1.0-1.0-0.9-0.90.6-0.60.40.70.60.6-0.5-0.50.50.40.1
Post-drug Anxiety0.10.21.1-0.80.50.5-1.10.4-0.3-0.3-0.2-0.2-0.10.10.00.6-0.10.1-0.1-0.10.10.00.4
Baseline Anxiety0.80.82.01.4-1.4-1.20.5-1.21.11.11.11.0-0.80.8-0.7-0.5-0.8-0.70.70.7-0.7-0.50.1
Tail length6.319.123.33.1-4.1-4.3-1.5-4.64.64.74.84.6-4.84.8-4.83.0-4.7-4.74.74.7-4.7-4.74.2
Length with tail3.311.915.72.0-2.7-3.2-1.9-3.33.53.53.53.3-3.93.9-4.02.8-4.0-3.63.83.8-3.8-3.83.7
Length without tail0.20.41.0-0.61.00.7-0.50.8-0.7-0.8-0.9-1.00.4-0.40.3-0.10.20.9-0.4-0.40.40.6-0.1
Times rat made contact with spout0.70.82.0-0.2-0.3-0.3-1.1-0.60.50.80.80.7-0.90.9-0.91.4-0.9-1.20.90.9-0.9-0.91.3
Lifetime Intake0.20.30.90.8-0.8-0.60.9-0.60.60.60.60.6-0.30.3-0.3-0.4-0.3-0.40.30.3-0.3-0.3-0.1
Liver weight, left1.32.14.6-0.4-0.3-0.6-2.0-0.80.91.11.11.1-1.51.5-1.52.1-1.5-1.61.71.7-1.7-1.72.0
Liver weight, right2.44.010.3-0.7-0.1-0.6-2.9-0.91.11.31.31.3-2.12.0-2.13.2-2.1-2.02.42.4-2.4-2.33.0
Locomotor activity0.30.41.61.2-1.1-0.81.2-0.80.50.70.60.50.0-0.00.1-0.60.1-0.8-0.0-0.00.0-0.1-0.3
Locomotor testing distance1.21.94.72.2-2.1-1.91.4-1.81.71.61.61.6-0.90.9-0.8-0.5-0.9-1.41.01.0-1.0-1.10.3
Locomotor testing rearing1.82.73.71.6-1.8-1.9-0.0-1.91.91.81.81.8-1.61.6-1.60.7-1.6-1.71.81.8-1.8-1.71.3
Locomotion in novel chamber0.70.93.60.5-0.20.21.90.3-0.4-0.5-0.5-0.51.1-1.11.2-1.61.20.3-0.9-0.90.90.8-1.5
Locomotion in novel chamber post-restriction0.91.15.51.2-0.7-0.42.0-0.3-0.1-0.1-0.2-0.40.6-0.50.7-2.30.61.0-1.1-1.11.11.2-1.6
Fecal boli incidents, locomotor time 10.30.42.20.7-0.3-0.31.50.0-0.1-0.2-0.30.00.5-0.60.5-1.20.50.2-0.4-0.40.40.3-1.0
Change in fecal boli incidents, locomotor task0.50.51.3-1.01.11.0-1.20.9-0.8-0.7-0.7-0.60.2-0.20.20.60.20.6-0.5-0.50.50.40.2
Time >=10cm from walls, locomotor time 10.50.53.10.9-0.6-0.31.8-0.30.00.0-0.00.10.3-0.20.3-1.50.30.6-0.6-0.60.60.3-1.1
Bouts of movement, locomotor time 10.10.10.30.3-0.0-0.20.6-0.00.3-0.1-0.10.1-0.10.1-0.1-0.3-0.10.40.40.4-0.4-0.0-0.1
Total resting periods, locomotor time 10.30.30.6-0.10.50.40.70.6-0.3-0.7-0.7-0.50.6-0.60.6-0.60.50.8-0.2-0.20.20.5-0.7
Rest time, locomotor task time 10.60.61.4-0.51.00.70.30.9-0.9-1.0-1.1-0.90.8-0.80.7-0.40.71.2-0.7-0.70.70.7-0.4
Distance moved, locomotor task time 11.41.53.00.8-1.3-1.0-0.4-1.41.21.51.61.5-1.11.2-1.10.9-1.1-1.71.21.2-1.2-1.41.0
Vertical activity count, locomotor time 11.11.22.30.8-1.4-1.1-0.3-1.31.21.41.51.3-1.21.2-1.20.4-1.1-1.50.70.7-0.7-0.90.5
Time >=10cm from walls, locomotor time 20.60.61.51.2-0.9-1.10.8-0.90.90.70.61.0-0.80.8-0.8-0.6-0.8-0.00.60.6-0.6-0.90.1
Bouts of movement, locomotor time 20.60.71.01.0-0.9-1.0-0.3-1.00.90.90.90.8-0.90.9-0.90.1-1.0-0.20.90.9-0.9-0.50.8
Total resting periods, locomotor time 20.40.40.80.7-0.6-0.7-0.6-0.70.70.70.60.5-0.90.9-0.80.2-0.90.10.70.7-0.7-0.30.7
Rest time, locomotor task time 21.21.44.0-2.01.71.7-1.51.5-1.5-1.2-1.1-1.10.8-0.80.90.90.80.5-0.9-0.90.90.7-0.1
Distance moved, locomotor task time 22.32.65.52.4-2.1-2.21.3-2.02.11.81.71.8-1.41.4-1.5-0.5-1.3-1.01.51.5-1.5-1.50.6
Vertical activity count, locomotor time 22.22.43.71.6-1.9-1.90.1-1.81.81.81.81.8-1.61.6-1.70.2-1.6-1.41.41.4-1.4-1.60.8
Light reinforcement 10.40.83.6-1.71.41.1-1.91.0-0.8-0.7-0.7-0.80.2-0.20.21.40.2-0.1-0.0-0.00.00.40.7
Light reinforcement 20.20.20.4-0.40.60.40.10.6-0.5-0.6-0.6-0.40.6-0.60.5-0.30.50.4-0.3-0.30.30.3-0.5
Bone: marrow area1.94.15.51.8-2.2-2.2-0.1-2.32.22.32.32.2-2.12.1-2.00.9-2.1-2.32.12.1-2.1-2.11.6
Bone: maximum diameter1.83.36.02.3-2.4-2.20.8-2.32.12.22.22.0-1.71.7-1.60.0-1.7-1.91.71.7-1.7-1.70.7
Bone: maximum force0.10.10.80.3-0.6-0.20.1-0.40.30.50.60.4-0.10.1-0.10.1-0.1-0.90.30.3-0.3-0.3-0.2
Bone: maximum moment0.20.31.20.5-0.8-0.50.3-0.70.50.70.80.6-0.30.3-0.30.1-0.3-1.10.50.5-0.5-0.5-0.1
Mean time between licks in bursts6.99.713.83.4-3.4-3.70.3-3.63.63.43.33.6-3.23.2-3.20.8-3.2-2.63.23.2-3.2-3.22.3
Mean num. licks in bursts1.21.45.52.3-1.9-1.72.2-1.51.21.21.11.1-0.40.4-0.4-1.4-0.4-0.60.40.4-0.4-0.4-0.6
Cd content in liver0.50.51.5-0.40.0-0.1-1.2-0.20.30.40.50.5-0.70.7-0.71.2-0.7-0.80.70.7-0.7-0.91.0
Co content in liver2.12.43.51.6-1.7-1.90.3-1.71.81.71.61.7-1.71.7-1.70.4-1.7-1.31.71.7-1.7-1.61.2
Cu content in liver1.62.02.71.3-1.3-1.6-0.2-1.51.61.41.31.5-1.61.6-1.60.5-1.6-0.91.61.6-1.6-1.51.4
Fe content in liver0.00.00.1-0.20.0-0.1-0.3-0.10.10.10.10.2-0.30.3-0.30.3-0.3-0.10.30.3-0.3-0.20.3
K content in liver0.20.20.6-0.1-0.1-0.2-0.8-0.30.30.30.30.3-0.50.5-0.50.7-0.5-0.50.50.5-0.5-0.40.8
Mg content in liver0.10.10.30.6-0.5-0.50.1-0.50.40.40.40.4-0.30.3-0.3-0.2-0.3-0.10.30.3-0.3-0.30.2
Mn content in liver2.32.63.6-1.61.91.8-0.11.9-1.8-1.9-1.9-1.81.6-1.61.7-0.51.61.6-1.6-1.61.61.6-1.1
Na content in liver0.10.10.80.5-0.2-0.30.6-0.10.1-0.1-0.2-0.10.2-0.20.2-0.90.20.7-0.3-0.30.30.4-0.4
Rb content in liver0.70.91.71.2-1.3-1.10.6-1.21.11.11.21.0-0.80.8-0.8-0.0-0.8-1.10.80.8-0.8-0.80.3
Se content in liver2.02.46.0-2.42.52.0-1.42.1-1.8-1.9-1.9-1.71.1-1.11.10.71.11.5-1.1-1.11.11.1-0.0
Sr content in liver0.50.40.6-0.20.40.40.50.6-0.6-0.6-0.7-0.60.7-0.70.7-0.70.70.8-0.7-0.70.70.7-0.8
Zn content in liver2.22.47.42.7-2.3-2.21.7-2.01.91.71.61.8-1.11.1-1.1-1.2-1.1-0.81.11.1-1.1-1.1-0.1
Bone: minimum diameter2.34.46.61.1-1.8-1.8-1.0-2.12.02.22.32.2-2.22.2-2.21.8-2.2-2.62.32.3-2.3-2.32.1
Time in familiar zone, hab. session 10.20.20.5-0.1-0.1-0.2-0.4-0.30.30.40.40.4-0.50.5-0.50.7-0.5-0.60.50.5-0.5-0.60.7
Time in novel zone, hab. session 10.00.00.2-0.30.20.2-0.50.1-0.2-0.1-0.0-0.10.1-0.10.00.20.1-0.1-0.0-0.00.00.00.1
Total zone transitions, hab. session 10.60.81.6-0.10.40.60.80.7-0.7-0.7-0.7-0.81.1-1.11.1-1.11.10.8-1.1-1.11.11.2-1.3
Total locomotion distance, hab. session 10.81.23.2-0.3-0.1-0.4-1.8-0.50.70.70.70.7-1.21.2-1.21.7-1.2-1.01.21.2-1.2-1.01.7
Locomotion velocity, hab. session 10.50.71.8-0.2-0.1-0.4-1.3-0.50.60.60.60.5-0.90.9-1.01.3-0.9-0.80.90.9-0.9-0.71.3
Time in familiar zone, hab. session 21.11.22.21.2-1.5-1.20.8-1.31.21.31.41.3-0.90.9-0.90.2-0.9-1.40.90.9-0.9-1.00.4
Time in novel zone, hab. session 20.70.71.8-0.61.00.8-0.20.9-0.8-1.1-1.2-0.80.8-0.80.8-0.50.81.3-0.7-0.70.70.7-0.4
Total zone transitions, hab. session 20.50.73.31.2-0.5-0.51.7-0.20.2-0.1-0.3-0.00.5-0.50.5-1.80.51.0-0.5-0.50.50.6-1.2
Total locomotion distance, hab. session 21.41.92.90.6-0.8-1.2-1.1-1.11.41.21.21.3-1.61.6-1.61.3-1.6-1.11.61.6-1.6-1.51.7
Locomotion velocity, hab. session 21.62.23.70.5-0.8-1.2-1.4-1.21.41.31.21.3-1.71.7-1.81.5-1.7-1.21.71.7-1.7-1.71.9
Novel to familiar place preference ratio0.00.00.20.20.0-0.10.20.00.1-0.1-0.2-0.10.1-0.10.1-0.40.10.5-0.1-0.10.10.2-0.1
Novelty place preference0.00.00.30.20.1-0.10.30.10.1-0.2-0.3-0.10.1-0.10.1-0.40.10.5-0.1-0.10.10.1-0.1
Time in novel zone, NPP test0.00.00.20.3-0.1-0.20.5-0.00.2-0.1-0.2-0.00.1-0.10.1-0.50.10.5-0.0-0.00.00.1-0.2
Total zone transitions, NPP test0.30.41.00.30.20.20.90.4-0.3-0.6-0.7-0.40.7-0.70.7-1.00.71.0-0.6-0.60.60.6-0.8
Total locomotion distance, NPP test0.70.92.9-0.20.2-0.4-1.4-0.30.70.40.30.6-1.11.1-1.11.4-1.1-0.31.21.2-1.2-1.11.7
Locomotion velocity, NPP test0.60.82.9-0.50.5-0.1-1.7-0.10.50.10.10.4-1.01.0-1.01.5-1.0-0.11.01.0-1.0-1.01.7
Intraocular pressure0.60.82.40.30.10.31.20.4-0.5-0.6-0.6-0.70.9-0.91.0-1.51.01.0-0.9-0.90.91.2-1.4
Delta distance traveled before/after self-admin0.60.71.6-0.10.50.41.30.7-0.5-0.8-0.8-0.80.8-0.80.8-1.00.80.9-0.8-0.80.81.0-1.1
Delta ambulatory time before/after self-admin1.01.12.1-0.20.70.51.40.9-0.7-1.1-1.2-1.11.0-1.01.0-1.41.01.4-1.0-1.01.01.3-1.4
Parametrial fat weight0.81.55.1-0.7-0.2-0.2-2.3-0.60.30.91.10.6-1.41.4-1.32.1-1.4-1.51.11.1-1.1-0.91.7
Pavlov. Cond. lever latency0.81.02.2-1.51.41.3-0.91.2-1.1-1.2-1.1-1.10.8-0.80.80.20.81.0-0.7-0.70.70.8-0.3
Pavlov. Cond. magazine entry latency2.02.65.52.3-2.2-2.11.3-2.01.91.81.81.8-1.41.4-1.4-0.4-1.4-1.41.31.3-1.3-1.40.4
Pavlov. Cond. change in total contacts0.80.92.21.5-1.2-1.40.8-1.11.21.00.91.1-0.90.9-0.9-0.3-0.9-0.50.80.8-0.8-0.90.4
Pavlov. Cond. index score2.22.85.62.4-2.3-2.21.2-2.11.91.91.91.9-1.51.5-1.5-0.2-1.5-1.61.41.4-1.4-1.50.6
Pavlov. Cond. latency score2.02.65.42.3-2.2-2.11.3-2.01.91.91.81.8-1.41.4-1.4-0.3-1.4-1.51.31.3-1.3-1.40.5
Pavlov. Cond. lever contacts1.31.52.61.6-1.5-1.60.6-1.51.41.41.41.5-1.11.1-1.20.2-1.1-1.31.11.1-1.1-1.20.7
Pavlov. Cond. magazine entry number1.82.35.7-2.42.22.1-1.61.9-1.7-1.7-1.7-1.71.2-1.21.20.71.21.2-1.1-1.11.11.2-0.2
Pavlov. Cond. intertrial magazine entries0.91.12.6-1.41.61.3-0.71.4-1.2-1.3-1.3-1.10.9-0.91.00.40.91.1-0.7-0.70.70.70.0
Pavlov. Cond. lever-magazine prob. diff.1.82.34.32.1-2.0-2.01.1-1.91.71.81.71.7-1.31.3-1.4-0.1-1.3-1.51.21.2-1.2-1.40.6
Pavlov. Cond. response bias1.21.42.51.6-1.5-1.60.6-1.41.41.41.31.4-1.11.1-1.20.1-1.1-1.21.01.0-1.0-1.10.7
Pavlov. Cond. lever latency7.710.330.7-5.54.94.6-3.74.2-3.9-3.5-3.3-3.52.3-2.32.32.52.31.8-2.2-2.22.22.20.3
Pavlov. Cond. magazine entry latency1.21.45.22.3-1.9-1.62.1-1.41.11.11.01.0-0.30.3-0.3-1.9-0.3-0.20.30.3-0.3-0.2-1.1
Pavlov. Cond. change in total contacts4.96.722.64.8-3.9-3.83.6-3.33.12.62.42.8-1.61.6-1.6-2.6-1.6-0.81.61.6-1.6-1.6-0.6
Pavlov. Cond. index score5.57.022.54.7-4.1-3.83.3-3.43.12.92.72.8-1.71.7-1.7-2.5-1.7-1.21.61.6-1.6-1.6-0.6
Pavlov. Cond. latency score4.75.819.54.4-3.8-3.53.2-3.12.82.62.42.5-1.51.5-1.5-2.5-1.5-1.01.41.4-1.4-1.3-0.7
Pavlov. Cond. lever contacts7.910.831.85.6-5.0-4.73.8-4.33.93.63.43.6-2.32.3-2.3-2.6-2.3-1.92.22.2-2.2-2.2-0.4
Pavlov. Cond. magazine entry number2.12.510.0-3.22.52.2-2.91.8-1.6-1.4-1.2-1.50.5-0.50.52.50.50.0-0.5-0.50.50.51.2
Pavlov. Cond. intertrial magazine entries1.62.13.50.4-0.8-1.0-1.1-1.21.31.31.41.3-1.61.6-1.61.7-1.6-1.71.61.6-1.6-1.61.9
Pavlov. Cond. lever-magazine prob. diff.5.46.921.34.6-4.0-3.83.1-3.43.12.82.72.9-1.81.8-1.8-2.3-1.8-1.21.71.7-1.7-1.7-0.4
Pavlov. Cond. response bias7.610.331.65.6-5.0-4.64.0-4.13.83.53.33.5-2.12.1-2.1-2.8-2.1-1.82.02.0-2.0-2.0-0.6
Time in closed arm before self-admin2.12.37.50.50.20.42.70.8-0.8-1.1-1.2-0.91.8-1.81.7-2.31.81.4-1.6-1.61.61.3-2.3
Time in closed arm after self-admin1.81.92.9-1.11.31.40.31.5-1.4-1.4-1.4-1.31.7-1.71.7-0.51.71.0-1.5-1.51.51.1-1.2
Time in open arm before self-admin0.80.85.4-1.71.31.1-2.30.8-0.7-0.5-0.5-0.5-0.20.2-0.11.5-0.20.30.20.2-0.2-0.01.2
Time in open arm after self-admin2.32.53.60.9-1.4-1.4-0.7-1.61.51.71.71.5-1.91.9-1.81.1-1.9-1.61.91.9-1.9-1.51.5
Bone: periosteal estimation1.83.65.01.9-2.2-2.10.2-2.22.12.22.22.1-1.81.8-1.80.7-1.8-2.22.02.0-2.0-2.01.2
Bone: periosteal perimeter1.83.04.91.9-2.2-2.00.4-2.12.02.12.11.9-1.51.5-1.50.4-1.5-2.11.71.7-1.7-1.70.9
Bone: post-yield work0.20.20.90.5-0.8-0.40.3-0.60.40.70.80.4-0.20.2-0.2-0.1-0.2-0.90.20.2-0.2-0.2-0.2
Progressive ratio test 1 active lever presses0.30.30.7-0.80.70.7-0.20.6-0.6-0.6-0.6-0.60.3-0.30.40.10.40.5-0.6-0.60.60.5-0.1
Progressive ratio test 1 breakpoint0.10.20.5-0.70.60.6-0.30.5-0.4-0.4-0.4-0.40.1-0.10.20.30.20.3-0.4-0.40.40.30.1
Progressive ratio test 1 inactive lever presses0.10.10.10.3-0.3-0.2-0.0-0.40.20.40.40.2-0.30.3-0.30.1-0.3-0.30.10.1-0.1-0.10.3
Progressive ratio test 2 active lever presses0.50.61.21.1-1.1-1.00.7-1.00.90.90.90.8-0.70.7-0.7-0.3-0.7-0.60.40.4-0.4-0.50.2
Progressive ratio test 2 breakpoint0.60.61.31.1-1.2-1.00.7-1.10.91.01.00.9-0.80.8-0.8-0.2-0.8-0.60.50.5-0.5-0.60.2
Progressive ratio test 2 inactive lever presses0.10.11.10.6-0.5-0.41.1-0.30.30.30.30.20.1-0.10.0-0.50.1-0.2-0.1-0.10.10.0-0.5
Incentive Sensitization - Responses1.61.63.31.8-1.8-1.71.0-1.61.51.51.51.4-1.11.1-1.1-0.4-1.1-1.00.90.9-0.9-1.00.3
Incentive Sensitization - Breakpoint1.31.33.01.7-1.7-1.61.2-1.51.41.31.31.3-0.90.9-1.0-0.5-0.9-0.90.80.8-0.8-0.80.1
Sum of active levers in priming session hrs 5-60.00.00.10.10.1-0.00.40.10.0-0.2-0.20.0-0.00.0-0.0-0.1-0.00.2-0.1-0.10.1-0.2-0.0
Progressive ratio0.30.40.90.10.20.30.70.3-0.7-0.4-0.4-0.60.6-0.60.6-0.70.60.5-0.9-0.90.90.8-0.6
Food seeking constrained by brief footshock1.61.92.91.6-1.7-1.70.2-1.71.61.61.61.5-1.51.5-1.40.2-1.4-1.11.31.3-1.3-1.31.0
Seeking ratio, punishment vs. effort2.42.94.31.2-1.5-1.7-0.6-1.72.01.71.71.9-1.91.9-1.80.9-1.8-1.42.12.1-2.1-1.81.5
Retroperitoneal fat weight3.210.631.7-1.7-0.1-0.8-5.6-1.31.62.02.21.9-3.53.4-3.65.4-3.6-3.33.43.4-3.4-3.34.9
Reaction time number correct1.01.41.9-0.00.60.61.40.9-0.9-1.1-1.2-1.11.3-1.31.3-1.41.31.4-1.3-1.31.31.4-1.4
Reaction time mean minus median0.81.11.81.1-1.4-1.20.3-1.31.21.31.31.2-1.01.0-1.10.1-1.0-1.21.01.0-1.0-1.00.5
Reaction time mean minus median AUC0.40.61.51.2-1.2-0.91.0-1.00.80.90.90.8-0.50.5-0.5-0.4-0.4-0.70.50.5-0.5-0.5-0.1
Reaction time num false alarms0.40.63.5-1.20.90.7-1.90.5-0.4-0.3-0.2-0.4-0.40.4-0.41.5-0.3-0.20.40.4-0.4-0.31.1
Reaction time num false alarms AUC0.20.31.6-0.90.90.6-1.30.6-0.4-0.4-0.4-0.4-0.10.1-0.11.0-0.10.20.10.1-0.1-0.10.8
Reaction time trials correct on left1.01.41.9-0.00.60.61.40.9-0.9-1.1-1.2-1.11.3-1.31.3-1.41.31.4-1.3-1.31.31.4-1.4
Reaction time trials on left1.01.41.9-0.00.60.71.40.9-0.9-1.1-1.2-1.11.4-1.41.3-1.41.31.4-1.3-1.31.31.4-1.4
Reaction time mean0.30.52.4-0.90.30.3-1.50.0-0.00.20.30.2-0.60.6-0.71.3-0.6-0.70.60.6-0.6-0.70.8
Reaction time mean AUC0.30.42.4-1.30.70.7-1.50.4-0.4-0.2-0.1-0.1-0.20.2-0.31.2-0.3-0.40.20.2-0.2-0.40.7
Median of all reaction times0.40.53.0-1.50.80.8-1.70.5-0.5-0.3-0.2-0.2-0.20.2-0.31.3-0.3-0.30.20.2-0.2-0.40.7
Reaction time omissions0.10.20.9-0.30.10.0-1.0-0.10.00.20.20.1-0.30.3-0.40.7-0.4-0.50.40.4-0.4-0.40.6
Reaction time false alarm rate0.50.73.7-1.00.70.4-1.90.2-0.1-0.00.0-0.0-0.70.7-0.61.6-0.6-0.40.60.6-0.6-0.61.3
Reaction time premature initiation rate4.25.67.71.9-2.5-2.4-0.6-2.62.52.72.82.6-2.62.6-2.51.2-2.5-2.72.42.4-2.4-2.51.8
Reaction time premature initiations1.62.33.81.7-1.9-1.80.3-1.81.81.81.81.7-1.51.5-1.40.2-1.4-1.61.41.4-1.4-1.40.7
Std. dev. reaction times1.31.82.40.6-1.2-1.1-0.8-1.31.21.41.51.4-1.51.5-1.51.0-1.5-1.51.51.5-1.5-1.51.2
Reaction time trials completed1.01.41.9-0.00.60.71.40.9-0.9-1.1-1.2-1.11.4-1.41.3-1.41.31.4-1.3-1.31.31.4-1.4
Reaction time trials AUC0.71.01.50.10.50.51.20.7-0.7-0.9-1.0-0.91.1-1.11.1-1.21.11.2-1.1-1.11.11.2-1.1
Run reversals in cocaine runway, females5.65.48.20.2-1.3-1.5-2.6-1.91.82.22.32.0-2.62.6-2.72.8-2.6-2.72.52.5-2.5-2.42.9
Run reversals in cocaine runway, males0.00.00.2-0.40.20.3-0.30.2-0.2-0.2-0.1-0.10.1-0.10.10.10.1-0.1-0.3-0.30.30.2-0.2
Latency to leave start box in cocaine runway0.60.74.8-1.21.00.6-2.20.5-0.3-0.4-0.3-0.5-0.50.5-0.51.3-0.50.40.30.3-0.30.11.2
Latency to leave start box in cocaine runway, F1.01.15.5-0.70.4-0.1-2.3-0.20.50.30.30.2-1.21.2-1.21.6-1.2-0.10.90.9-0.9-0.61.8
Latency to leave start box in cocaine runway, M0.70.71.0-0.90.91.0-0.10.9-1.0-0.9-0.9-1.00.9-0.90.9-0.30.90.8-0.8-0.80.81.0-0.7
Std. dev. time between licks in bursts3.84.65.71.7-2.0-2.2-0.6-2.32.32.32.22.3-2.42.4-2.41.2-2.4-1.92.32.3-2.3-2.22.1
Total sessions with >9 infusions0.50.52.91.3-1.1-0.81.7-0.70.70.50.50.50.0-0.00.0-1.40.0-0.0-0.1-0.10.10.1-0.9
Short access day 1 total inactive lever presses0.20.20.4-0.60.70.6-0.30.6-0.4-0.5-0.5-0.50.4-0.40.50.20.40.3-0.3-0.30.30.3-0.1
Short access day 10 total inactive lever presses0.20.20.3-0.40.50.50.10.5-0.4-0.5-0.5-0.50.5-0.50.4-0.10.50.4-0.4-0.40.40.4-0.3
Short access day 1 total infusions0.90.92.31.5-1.4-1.31.0-1.31.21.11.11.0-0.80.8-0.7-0.5-0.8-0.70.60.6-0.6-0.70.1
Short access day 10 total infusions0.60.71.11.0-1.0-1.10.6-1.01.00.90.90.9-0.80.8-0.80.0-0.8-0.70.80.8-0.8-0.80.5
Short access total infusions0.50.50.90.8-1.0-0.90.4-0.90.90.90.90.9-0.70.7-0.70.0-0.7-0.70.60.6-0.6-0.70.4
Short access day 1 locomotion0.91.04.10.9-0.4-0.11.90.1-0.2-0.4-0.4-0.40.8-0.80.8-2.00.81.1-1.0-1.01.01.0-1.5
Short access day 10 total locomotion0.10.10.40.6-0.5-0.50.6-0.40.50.30.20.4-0.10.1-0.2-0.4-0.1-0.00.20.2-0.2-0.3-0.1
Short access total locomotion0.00.00.20.2-0.1-0.00.40.00.0-0.1-0.1-0.00.2-0.20.1-0.50.20.3-0.2-0.20.20.2-0.3
One hour access (0.3 mA shock)0.50.62.31.5-1.3-1.11.4-1.00.80.80.80.8-0.30.3-0.3-0.9-0.3-0.40.30.3-0.3-0.3-0.4
Compulsive drug intake0.50.50.90.10.30.30.60.5-0.6-0.6-0.7-0.70.6-0.60.7-1.00.60.9-0.8-0.80.80.9-0.9
One hour access (shock baseline)0.40.51.21.1-1.1-0.91.1-0.90.90.80.80.8-0.50.5-0.5-0.4-0.4-0.50.50.5-0.5-0.4-0.0
Social response proportion0.20.21.0-0.60.30.1-0.90.10.00.00.10.1-0.20.2-0.31.0-0.2-0.40.40.4-0.4-0.50.8
Social responses0.91.12.8-0.2-0.2-0.5-1.5-0.60.70.80.80.7-1.11.1-1.21.7-1.2-1.11.21.2-1.2-1.21.7
Social time1.92.55.4-2.12.31.9-1.12.0-1.8-2.0-2.0-1.91.2-1.21.20.31.21.7-1.3-1.31.31.3-0.3
Soleus weight1.75.17.60.3-1.3-1.5-2.0-1.81.92.22.32.0-2.52.5-2.52.6-2.5-2.72.52.5-2.5-2.52.7
Bone: stiffness0.30.41.0-0.3-0.2-0.2-1.0-0.40.30.50.60.4-0.70.7-0.71.0-0.7-1.00.70.7-0.7-0.60.7
Tibialis anterior weight0.41.31.70.7-1.1-1.1-0.5-1.21.21.31.31.2-1.31.3-1.30.8-1.3-1.31.31.3-1.3-1.31.0
Time to tail flick, vehicle, before self-admin0.10.10.2-0.30.10.50.30.3-0.3-0.1-0.10.10.5-0.50.50.20.5-0.5-0.0-0.00.0-0.3-0.3
Time to tail flick, vehicle, after self-admin0.50.52.91.2-1.0-0.71.7-0.60.50.40.40.30.2-0.20.3-1.20.2-0.1-0.3-0.30.30.2-0.9
Time to tail flick, test, before self-admin0.90.91.40.6-0.8-0.8-0.4-0.91.00.90.91.1-1.21.1-1.20.5-1.2-0.81.01.0-1.0-1.00.8
Time to tail flick, test, after self-admin1.41.52.30.8-0.9-1.2-0.8-1.21.41.11.11.2-1.31.3-1.40.8-1.3-0.81.51.5-1.5-1.21.4
Delta time to tail flick, vehicle, before/after SA0.40.42.01.1-0.8-0.81.0-0.60.40.30.2-0.0-0.20.20.1-1.4-0.20.7-0.5-0.50.50.8-0.6
Delta time to tail flick, test, before/after SA0.10.10.4-0.30.50.3-0.50.3-0.3-0.4-0.4-0.40.2-0.20.30.00.20.6-0.1-0.10.10.30.2
Tibia length0.51.58.21.9-0.9-0.72.9-0.30.2-0.1-0.2-0.20.8-0.80.8-2.70.81.1-0.8-0.80.80.9-1.9
Ambulatory time before self-admin0.70.71.3-1.11.01.1-0.60.9-1.1-0.8-0.8-0.80.9-0.90.90.20.90.5-0.8-0.80.80.6-0.3
Ambulatory time after self-admin3.53.85.4-1.72.12.00.92.3-2.1-2.3-2.3-2.22.1-2.12.0-1.02.12.0-1.9-1.91.91.9-1.7
Bone: tissue strength2.32.23.0-0.81.11.30.81.4-1.5-1.5-1.5-1.51.7-1.71.7-1.31.71.6-1.7-1.71.71.7-1.7
Total heroin consumption0.10.10.90.4-0.2-0.30.9-0.10.30.10.00.3-0.20.2-0.0-0.4-0.20.10.00.0-0.0-0.3-0.2
Bone: trabecular number1.11.72.9-1.51.31.7-0.11.4-1.6-1.2-1.0-1.51.6-1.61.60.21.60.1-1.2-1.21.21.2-1.0
Bone: trabecular spacing0.20.31.21.1-0.6-0.80.9-0.60.60.30.20.5-0.30.3-0.3-1.1-0.30.60.00.0-0.00.0-0.2
Bone: trabecular thickness0.20.21.1-0.4-0.00.1-0.6-0.10.10.30.40.2-0.20.2-0.21.0-0.2-1.00.50.5-0.5-0.60.5
Bone: trabecular tissue density1.21.75.0-0.70.1-0.3-2.2-0.50.60.70.80.8-1.51.5-1.52.1-1.5-1.01.41.4-1.4-1.32.0
Water consumed over 24 hours0.50.61.3-1.11.01.1-0.41.0-1.0-0.8-0.8-0.80.8-0.80.80.50.80.2-0.7-0.70.70.6-0.1
Number of responses in last shaping day1.01.01.40.9-1.0-1.0-0.1-1.01.21.11.11.1-0.90.9-1.00.6-0.9-1.21.11.1-1.1-1.20.8