Hub : Traits

Time to tail flick, test, after self-admin

Time in sec to remove tail from noxious stimuli under test conditions in the second tail flick after self admin

Tags: Behavior · Heroin

Project: u01_peter_kalivas

4 loci · 5 genes with independent associations · 6 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr2	144511896	145907690	1	1	2.17e-09	2.11e-01	1.00e+00	Mindy4b
2	chr7	92127461	93066096	1	1	6.94e-20	5.86e-01	1.00e+00	Ndufb9
3	chr9	83390749	84777604	1	1	0.00e+00	1.34e-01	1.00e+00	Retreg2
4	chr10	24930750	26383343	3	2	4.04e-12	2.47e-02	9.29e-06	Ccng1 Mat2b

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	223.28	4	3	60	-0.85	1.51e-01	Ccng1 Mindy4b Ndufb9 Retreg2
BMI without tail	9545.98	5	2	40	0.92	8.87e-03	Ccng1 Mat2b Mindy4b Ndufb9 Retreg2
Body weight	8.05	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Epididymis fat weight	18141.5	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Glucose	273.97	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Heart weight	1536.76	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Left kidney weight	18352.75	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Right kidney weight	20206.48	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Tail length	28919.24	1	1	20	0	1.00e+00	Retreg2
Length with tail	746.74	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Length without tail	15748.54	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Liver weight, left	1747.19	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Liver weight, right	19.08	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Parametrial fat weight	50.06	3	1	20	1	2.78e-03	Ccng1 Mat2b Retreg2
Retroperitoneal fat weight	789.45	4	1	20	0.96	1.13e-02	Ccng1 Mat2b Mindy4b Retreg2
Intraocular pressure	2601.09	3	1	20	-0.94	6.49e-02	Ccng1 Mat2b Retreg2
Extensor digitorum longus weight	540.26	2	1	20	0	1.00e+00	Mindy4b Retreg2
Soleus weight	12.63	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Tibialis anterior weight	1158.38	1	1	20	0	1.00e+00	Retreg2
Tibia length	385.43	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Number of licking bursts	67424.86	1	1	20	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	35509.41	1	1	20	0	1.00e+00	Retreg2
Times rat made contact with spout	41.61	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Mean time between licks in bursts	55817.09	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Mean num. licks in bursts	56750.08	1	1	20	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	29750.31	1	1	20	0	1.00e+00	Retreg2
Water consumed over 24 hours	34168.6	1	1	20	0	1.00e+00	Retreg2
Patch foraging indifference point 0 sec	39171.5	1	1	20	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	25072.33	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Indifference point function ln k	27852.12	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Indifference point function log k	27852.12	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 0 sec	41947.04	1	1	20	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	1174.88	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 18 sec	20233.2	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 24 sec	24966.79	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Patch foraging total patch changes 6 sec	2604.03	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Patch foraging time to switch 0 sec	33254.99	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 0 sec	20147.41	3	1	20	0	1.00e+00	Ccng1 Ndufb9 Retreg2
Patch foraging water rate 12 sec	35321.86	2	1	20	0	1.00e+00	Ccng1 Retreg2
Patch foraging water rate 18 sec	16866.98	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 24 sec	1033.47	1	1	20	0	1.00e+00	Retreg2
Patch foraging water rate 6 sec	178.04	4	2	40	-0.84	7.45e-02	Ccng1 Mat2b Ndufb9 Retreg2
Locomotor testing distance	13837.71	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Locomotor testing rearing	21135.22	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Light reinforcement 1	33158.6	2	1	20	0	1.00e+00	Mindy4b Retreg2
Light reinforcement 2	12249.52	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Reaction time number correct	15874.5	3	2	40	-0.94	6.27e-02	Mat2b Ndufb9 Retreg2
Reaction time mean minus median	59977.3	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Reaction time mean minus median AUC	62002.11	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Reaction time num false alarms	5123.78	2	1	20	0	1.00e+00	Mat2b Retreg2
Reaction time num false alarms AUC	11676.23	2	1	20	0	1.00e+00	Mat2b Retreg2
Reaction time trials correct on left	15874.5	3	2	40	-0.94	6.27e-02	Mat2b Ndufb9 Retreg2
Reaction time trials on left	12182.8	4	2	40	-0.93	1.99e-02	Ccng1 Mat2b Ndufb9 Retreg2
Reaction time mean	14876.61	2	2	40	0	1.00e+00	Mindy4b Retreg2
Reaction time mean AUC	19397.23	2	2	40	0	1.00e+00	Mindy4b Retreg2
Median of all reaction times	3966.33	2	2	40	0	1.00e+00	Mindy4b Retreg2
Reaction time omissions	1403.24	5	1	20	0.9	1.56e-02	Ccng1 Mat2b Mindy4b Ndufb9 Retreg2
Reaction time false alarm rate	108.16	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Reaction time premature initiation rate	4871.37	2	1	20	0	1.00e+00	Mindy4b Retreg2
Reaction time premature initiations	26874.85	2	1	20	0	1.00e+00	Mindy4b Retreg2
Std. dev. reaction times	20292.58	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Reaction time trials completed	12182.8	4	2	40	-0.93	1.99e-02	Ccng1 Mat2b Ndufb9 Retreg2
Reaction time trials AUC	15538.7	3	1	20	-0.94	6.18e-02	Mat2b Ndufb9 Retreg2
Social response proportion	4394.41	2	1	20	0	1.00e+00	Mindy4b Retreg2
Social responses	426.87	3	1	20	0	1.00e+00	Ccng1 Ndufb9 Retreg2
Social time	11650.06	1	1	20	0	1.00e+00	Retreg2
Conditioned locomotion	1400.08	1	1	20	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	19128.47	1	1	20	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	18571.31	1	1	20	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	20	0	1.00e+00	Retreg2
Saline control response	3160.68	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	14521.56	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	14360.59	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active responses	2302.04	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	10889.7	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	1935.17	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. lever reinforcers received	469.54	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	2531.81	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	13282.18	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	19909.31	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. index score	12744.53	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	16150.81	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	5331.08	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	4012.39	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	34989.79	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	11800.43	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	1164.95	1	1	20	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	33615.25	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Conditioned reinforcement - inactives	32455.53	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Conditioned locomotion	3477.64	3	3	60	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Intermittent access intake day 1-15 change	63944.5	2	1	20	0	1.00e+00	Mindy4b Retreg2
Intermittent access intake escalation	25220.29	4	2	40	0.93	2.10e-02	Ccng1 Mat2b Mindy4b Retreg2
Intermittent access intake escalation 2	9055.93	3	1	20	0.94	6.30e-02	Ccng1 Mat2b Retreg2
Intermitt. access day 1 inactive lever presses	90309.52	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Intermitt. access day 15 inactive lever presses	41247.28	3	2	40	0	1.00e+00	Ccng1 Ndufb9 Retreg2
Intermitt. access escalation Index	15558.33	5	1	20	-0.92	9.80e-03	Ccng1 Mat2b Mindy4b Ndufb9 Retreg2
Intermittent access day 1 total infusions	33063.12	2	1	20	0	1.00e+00	Mindy4b Retreg2
Intermittent access day 15 total infusions	24370.06	2	1	20	0	1.00e+00	Ccng1 Retreg2
Intermittent access terminal intake (last 3 days)	12406.69	2	1	20	0	1.00e+00	Ccng1 Retreg2
Intermittent access total infusions	94.73	2	1	20	0	1.00e+00	Ccng1 Retreg2
Intermittent access day 1 locomotion	17488.68	2	1	20	0	1.00e+00	Mindy4b Retreg2
Intermittent access day 15 total locomotion	85548.8	1	1	20	0	1.00e+00	Retreg2
Intermittent access total locomotion	28.24	5	1	20	0.76	7.94e-02	Ccng1 Mat2b Mindy4b Ndufb9 Retreg2
Intermittent access standard deviation	113962.95	1	1	20	0	1.00e+00	Retreg2
Cocaine induced anxiety	23062.86	3	2	40	0	1.00e+00	Ccng1 Ndufb9 Retreg2
Post-drug Anxiety	1199.41	4	2	40	-1	9.30e-04	Ccng1 Mat2b Ndufb9 Retreg2
Baseline Anxiety	11237.13	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Lifetime Intake	1655.49	1	1	20	0	1.00e+00	Retreg2
Incentive Sensitization - Responses	23801.91	3	3	60	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Incentive Sensitization - Breakpoint	18440.68	3	3	60	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Progressive ratio test 1 active lever presses	10666.3	3	1	20	0	1.00e+00	Ccng1 Ndufb9 Retreg2
Progressive ratio test 1 breakpoint	10105.19	3	1	20	0	1.00e+00	Ccng1 Ndufb9 Retreg2
Progressive ratio test 1 inactive lever presses	31117.61	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 2 active lever presses	5093.11	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Progressive ratio test 2 breakpoint	4276.62	2	1	20	0	1.00e+00	Mindy4b Retreg2
Progressive ratio test 2 inactive lever presses	36254.71	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Total sessions with >9 infusions	988.9	2	1	20	0	1.00e+00	Mindy4b Retreg2
Short access day 1 total inactive lever presses	6580.86	5	3	60	-0.92	9.73e-03	Ccng1 Mat2b Mindy4b Ndufb9 Retreg2
Short access day 10 total inactive lever presses	138842.31	1	1	20	0	1.00e+00	Retreg2
Short access day 1 total infusions	38385.19	1	1	20	0	1.00e+00	Retreg2
Short access day 10 total infusions	7575.13	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Short access total infusions	4396.25	2	1	20	0	1.00e+00	Mindy4b Retreg2
Short access day 1 locomotion	12422.14	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Short access day 10 total locomotion	44107.69	2	2	40	0	1.00e+00	Mindy4b Retreg2
Short access total locomotion	6236.8	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Compulsive drug intake	6232.94	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
One hour access (0.3 mA shock)	783.36	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
One hour access (shock baseline)	54988.81	1	1	20	0	1.00e+00	Retreg2
Number of responses in last shaping day	6815.75	2	1	20	0	1.00e+00	Mindy4b Retreg2
Context. condit. distance diff. score	212.47	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 1	1769.63	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Locomotion distance, session 1	1024.77	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 2	2158.08	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 2	508.11	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 3	507.49	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 3	4009.46	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	1361.96	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	2872.44	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 7	292.79	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 7	435.3	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving bouts, day 7	1279.33	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving duration, day 7	1081.37	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Locomotion velocity, session 8	409.23	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 8	147.88	1	1	20	0	1.00e+00	Retreg2
Degree of sensitization distance	3670.85	1	1	20	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	1029.63	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active minus inactive responses	484.11	2	1	20	0	1.00e+00	Mindy4b Retreg2
Condit. Reinf. active-inactive response ratio	126.1	2	1	20	0	1.00e+00	Mindy4b Retreg2
Condit. Reinf. active responses	1386.69	2	1	20	0	1.00e+00	Mindy4b Retreg2
Condit. Reinf. inactive responses	2347.53	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Incentive salience index mean	3540.72	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	5282.33	1	1	20	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 1	11168.49	1	1	20	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	9232.79	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	221.7	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 1	394.1	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	266.96	1	1	20	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	5880.03	1	1	20	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	6311.49	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	35.66	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 2	22.17	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 2	31.27	1	1	20	0	1.00e+00	Retreg2
Novel to familiar place preference ratio	15339.58	1	1	20	0	1.00e+00	Retreg2
Novelty place preference	14927.56	1	1	20	0	1.00e+00	Retreg2
Time in novel zone, NPP test	10685.62	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, NPP test	980.79	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, NPP test	1687.31	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	953.07	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	491.79	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	1037.76	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. index score	384.43	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	404.63	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	344.19	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. magazine entry number	491.61	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	69.21	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	418.89	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	583.93	1	1	20	0	1.00e+00	Retreg2
Bone: apparent density	2735.95	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone surface	6197.68	1	1	20	0	1.00e+00	Retreg2
Bone volume	8624.75	1	1	20	0	1.00e+00	Retreg2
Bone: connectivity density	841.82	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical apparent density	6014.36	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical area	2293.91	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	221.79	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	560.57	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical thickness	191.17	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical thickness	979.4	3	1	20	0	1.00e+00	Ccng1 Ndufb9 Retreg2
Bone: cortical tissue density	6505.97	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: elastic displacement	7604.03	1	1	20	0	1.00e+00	Retreg2
Bone: elastic work	361.86	1	1	20	0	1.00e+00	Retreg2
Bone: endosteal estimation	4460.13	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: endosteal perimeter	11863.6	1	1	20	0	1.00e+00	Retreg2
Bone: final force	1600.36	1	1	20	0	1.00e+00	Retreg2
Bone: final moment	219.15	1	1	20	0	1.00e+00	Retreg2
Bone: marrow area	4718.77	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum diameter	3037.24	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum force	8697.09	1	1	20	0	1.00e+00	Retreg2
Bone: maximum moment	5989.29	1	1	20	0	1.00e+00	Retreg2
Bone: minimum diameter	4100.86	1	1	20	0	1.00e+00	Retreg2
Bone: periosteal estimation	9791.57	1	1	20	0	1.00e+00	Retreg2
Bone: periosteal perimeter	11400.25	1	1	20	0	1.00e+00	Retreg2
Bone: post-yield work	6839.22	2	1	20	0	1.00e+00	Mindy4b Retreg2
Bone: stiffness	9032.86	1	1	20	0	1.00e+00	Retreg2
Bone: tissue strength	2995.95	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular number	5387.39	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular spacing	3988.39	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular thickness	8476.26	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular tissue density	7288.68	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Breakpoint value in progressive ratio session	12540.97	2	1	20	0	1.00e+00	Mat2b Retreg2
Distance traveled before self-admin	25271.77	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Distance traveled after self-admin	32464.08	1	1	20	0	1.00e+00	Retreg2
Delta time in closed arm before/after self-admin	58.1	4	1	20	0.91	3.44e-02	Ccng1 Mat2b Ndufb9 Retreg2
Delta time in open arm before/after self-admin	3791.15	3	1	20	0.93	6.66e-02	Ccng1 Mat2b Retreg2
Diff in mean of infusions in LGA sessions	9167.24	3	1	20	-0.93	7.12e-02	Mat2b Ndufb9 Retreg2
Extinction: sum of active levers before priming	9473.6	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Active lever presses in extinction session 6	738.98	1	1	20	0	1.00e+00	Retreg2
Delta distance traveled before/after self-admin	1485.64	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Delta ambulatory time before/after self-admin	15429.45	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Time in closed arm before self-admin	13439.08	2	1	20	0	1.00e+00	Ccng1 Retreg2
Time in closed arm after self-admin	1156.64	3	1	20	0.98	2.44e-02	Ccng1 Mat2b Retreg2
Time in open arm before self-admin	2209.69	4	2	40	-0.92	8.13e-02	Ccng1 Mindy4b Ndufb9 Retreg2
Time in open arm after self-admin	261.21	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Sum of active levers in priming session hrs 5-6	203.81	4	1	20	0.94	1.93e-02	Ccng1 Mat2b Ndufb9 Retreg2
Time to tail flick, vehicle, before self-admin	4460.73	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Time to tail flick, vehicle, after self-admin	14057.65	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Time to tail flick, test, before self-admin	4093.6	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Delta time to tail flick, vehicle, before/after SA	4908.61	2	1	20	0	1.00e+00	Mindy4b Retreg2
Delta time to tail flick, test, before/after SA	2625.93	5	2	40	0.94	5.42e-03	Ccng1 Mat2b Mindy4b Ndufb9 Retreg2
Ambulatory time before self-admin	78874.38	1	1	20	0	1.00e+00	Retreg2
Ambulatory time after self-admin	26614.91	1	1	20	0	1.00e+00	Retreg2
Total heroin consumption	67.58	3	1	20	1	2.59e-03	Ccng1 Mat2b Retreg2
Area under the delay curve	12400.09	2	1	20	0	1.00e+00	Mindy4b Retreg2
Delay disc. indifference point, 0s delay	440	4	1	20	0.98	3.48e-03	Ccng1 Mat2b Mindy4b Retreg2
Delay disc. indifference point, 16s delay	10984.61	2	1	20	0	1.00e+00	Mindy4b Retreg2
Delay disc. indifference point, 2s delay	83.07	2	1	20	0	1.00e+00	Mindy4b Retreg2
Delay disc. indifference point, 24s delay	32437.06	1	1	20	0	1.00e+00	Retreg2
Delay disc. indifference point, 4s delay	216.13	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Delay disc. indifference point, 8s delay	33362.4	1	1	20	0	1.00e+00	Retreg2
Delay discount exponential model param	8465.49	2	1	20	0	1.00e+00	Mindy4b Retreg2
Delay discount hyperbolic model param	3075.71	3	1	20	0.95	5.16e-02	Mat2b Mindy4b Retreg2
Fecal boli incidents, locomotor time 1	61202.36	1	1	20	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	1904.41	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Time >=10cm from walls, locomotor time 1	3262.1	4	1	20	-0.95	5.17e-02	Ccng1 Mindy4b Ndufb9 Retreg2
Bouts of movement, locomotor time 1	10785.17	1	1	20	0	1.00e+00	Retreg2
Total resting periods, locomotor time 1	2793.59	1	1	20	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	11183.83	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Distance moved, locomotor task time 1	34443.92	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Vertical activity count, locomotor time 1	142354.07	1	1	20	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	23732	3	2	40	0	1.00e+00	Ccng1 Mindy4b Retreg2
Bouts of movement, locomotor time 2	41021.38	2	1	20	0	1.00e+00	Mindy4b Retreg2
Total resting periods, locomotor time 2	49524.91	2	1	20	0	1.00e+00	Mindy4b Retreg2
Rest time, locomotor task time 2	8506.57	3	1	20	0	1.00e+00	Ccng1 Ndufb9 Retreg2
Distance moved, locomotor task time 2	2832.66	3	1	20	0	1.00e+00	Ccng1 Mindy4b Retreg2
Vertical activity count, locomotor time 2	26790.07	2	2	40	0	1.00e+00	Mindy4b Retreg2
Weight adjusted by age	35416.78	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, delayed vs. immediate footshock	6730.03	2	1	20	0	1.00e+00	Mindy4b Retreg2
Locomotion in novel chamber	1993.33	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Locomotion in novel chamber post-restriction	21811.96	3	1	20	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Progressive ratio	33967.16	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Food seeking constrained by brief footshock	941.83	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, punishment vs. effort	20653.58	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Run reversals in cocaine runway, females	9406.04	1	1	20	0	1.00e+00	Retreg2
Run reversals in cocaine runway, males	1947.15	3	2	40	0.97	2.86e-02	Mat2b Ndufb9 Retreg2
Latency to leave start box in cocaine runway	16290.75	1	1	20	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, F	2400.69	3	2	40	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Latency to leave start box in cocaine runway, M	867.32	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Co content in liver	1133.25	1	1	20	0	1.00e+00	Retreg2
Cu content in liver	28.08	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Fe content in liver	1344.53	1	1	20	0	1.00e+00	Retreg2
K content in liver	1519.62	1	1	20	0	1.00e+00	Retreg2
Mg content in liver	6026.97	1	1	20	0	1.00e+00	Retreg2
Mn content in liver	537.3	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Na content in liver	2013.84	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Rb content in liver	71.08	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Se content in liver	8.63	1	0	0	0	1.00e+00	Ndufb9
Zn content in liver	1887.46	2	2	40	0	1.00e+00	Ndufb9 Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.05
Adipose	alternative TSS	0	0	1
Adipose	gene expression	0	0	1.01
Adipose	isoform ratio	0	0	1.03
Adipose	intron excision ratio	0	0	1.13
Adipose	mRNA stability	1	0	1.05
BLA	alternative polyA	0	0	1.02
BLA	alternative TSS	0	0	0.98
BLA	gene expression	0	0	1.03
BLA	isoform ratio	0	0	1.02
BLA	intron excision ratio	0	0	1.07
BLA	mRNA stability	0	0	1.05
Brain	alternative polyA	0	0	1.03
Brain	alternative TSS	0	0	0.97
Brain	gene expression	0	0	1.01
Brain	isoform ratio	0	0	1
Brain	intron excision ratio	0	0	1.11
Brain	mRNA stability	0	0	1
Eye	alternative polyA	0	0	0.91
Eye	alternative TSS	0	0	0.93
Eye	gene expression	0	0	1
Eye	isoform ratio	0	0	1.01
Eye	intron excision ratio	0	0	1.17
Eye	mRNA stability	0	0	0.98
IC	alternative polyA	0	0	1.07
IC	alternative TSS	0	0	1.01
IC	gene expression	0	0	1.03
IC	isoform ratio	0	0	0.98
IC	intron excision ratio	0	0	1.15
IC	mRNA stability	0	0	1.08
IL	alternative polyA	0	0	1.01
IL	alternative TSS	0	0	1.03
IL	gene expression	0	0	1.03
IL	isoform ratio	0	0	0.98
IL	intron excision ratio	0	0	1.02
IL	mRNA stability	0	0	1.07
LHb	alternative polyA	0	0	0.95
LHb	alternative TSS	0	0	1.06
LHb	gene expression	0	0	1.02
LHb	isoform ratio	0	0	0.95
LHb	intron excision ratio	0	0	1.07
LHb	mRNA stability	0	0	1.01
Liver	alternative polyA	0	0	1.1
Liver	alternative TSS	0	0	1.01
Liver	gene expression	0	0	1.03
Liver	isoform ratio	0	0	1.03
Liver	intron excision ratio	2	0	1.09
Liver	mRNA stability	0	0	1.01
NAcc	alternative polyA	1	0	1.45
NAcc	alternative TSS	0	0	1.02
NAcc	gene expression	0	0	1.01
NAcc	isoform ratio	0	0	1
NAcc	intron excision ratio	1	0	1.14
NAcc	mRNA stability	0	0	1.04
OFC	alternative polyA	0	0	0.98
OFC	alternative TSS	0	0	0.96
OFC	gene expression	0	0	0.99
OFC	isoform ratio	0	0	0.98
OFC	intron excision ratio	0	0	1
OFC	mRNA stability	0	0	1.06
PL	alternative polyA	0	0	1.07
PL	alternative TSS	0	0	1.01
PL	gene expression	0	0	1
PL	isoform ratio	0	0	1.03
PL	intron excision ratio	0	0	1.09
PL	mRNA stability	0	0	1.03
pVTA	alternative polyA	0	0	1.04
pVTA	alternative TSS	0	0	0.95
pVTA	gene expression	1	0	1.02
pVTA	isoform ratio	0	0	1.04
pVTA	intron excision ratio	0	0	1.2
pVTA	mRNA stability	0	0	1.08
RMTg	alternative polyA	0	0	1.12
RMTg	alternative TSS	0	0	1.09
RMTg	gene expression	0	0	1.07
RMTg	isoform ratio	0	0	1.09
RMTg	intron excision ratio	0	0	1.12
RMTg	mRNA stability	0	0	1.08