Hub : Genes

Pgm2l1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Pgm2l1 0.47 0.16 0.0e+00 0.3 0.37 0.39 0.39 3.3e-16 7.5e-21 2.2e-22 2.1e-22
2 Adipose gene expression Pgm2l1 0.15 0.1 9.8e-10 0.07 0.06 0.05 0.07 2.0e-08 3.7e-07 4.0e-06 2.7e-08
3 NAcc gene expression Pgm2l1 0.32 0.17 0.0e+00 0.16 0.15 0.16 0.16 1.8e-18 6.5e-17 9.0e-18 7.1e-18
4 Brain gene expression Pgm2l1 0.57 0.17 0.0e+00 0.37 0.51 0.51 0.51 2.6e-36 5.9e-54 2.5e-54 6.8e-54
5 PL gene expression Pgm2l1 0.3 0.13 0.0e+00 0.28 0.34 0.34 0.34 7.1e-31 5.7e-39 1.1e-38 6.4e-38
6 IL gene expression Pgm2l1 0.67 0.19 3.0e-10 0.18 0.16 0.16 0.16 4.6e-05 8.9e-05 9.5e-05 9.8e-05
7 OFC gene expression Pgm2l1 0.61 0.17 1.3e-13 0.39 0.36 0.37 0.37 3.2e-10 2.1e-09 8.2e-10 8.6e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.10.20.2-0.4-0.4-0.0-0.00.40.4
Area under the delay curve0.10.10.10.1-0.2-0.2-0.20.3-0.3-0.3
BMI with tail0.10.20.50.3-0.00.2-0.30.3-0.7-0.7
BMI without tail0.51.02.0-0.21.41.40.00.4-1.2-1.2
Body weight0.31.43.00.11.21.3-0.30.7-1.7-1.7
Weight adjusted by age0.30.41.0-0.51.01.00.4-0.2-0.3-0.3
Bone surface0.71.31.6-1.21.31.31.2-1.10.90.9
Bone volume0.50.80.9-1.00.90.91.0-0.90.80.8
Breakpoint value in progressive ratio session0.20.20.60.2-0.7-0.8-0.20.10.10.1
Number of licking bursts6.17.28.52.9-2.4-2.4-2.82.8-2.7-2.7
Context. condit. distance diff. score3.03.64.4-2.11.51.52.0-2.12.02.0
Locomotion velocity, session 10.20.20.60.3-0.7-0.7-0.1-0.00.40.4
Locomotion distance, session 11.11.42.1-1.20.80.81.2-1.31.41.4
Locomotion velocity, session 20.00.00.1-0.30.30.30.2-0.20.10.1
Locomotion distance, session 20.50.70.9-0.90.70.70.9-0.90.90.9
Locomotion velocity, session 31.01.11.9-1.10.40.41.1-1.21.41.4
Locomotion distance, session 31.92.03.2-1.40.70.71.5-1.61.81.8
Stereotopy head waving bouts, day 30.50.61.10.7-0.4-0.4-0.80.9-1.1-1.1
Stereotopy head waving duration, day 30.10.10.2-0.40.10.10.3-0.40.40.4
Locomotion velocity, session 70.20.20.50.4-0.7-0.7-0.40.3-0.1-0.1
Locomotion distance, session 70.20.20.20.5-0.4-0.4-0.50.5-0.4-0.4
Stereotopy head waving bouts, day 73.13.54.1-2.01.61.62.0-2.01.91.9
Stereotopy head waving duration, day 73.44.25.3-2.31.91.92.2-2.21.91.9
Locomotion velocity, session 80.81.01.2-1.10.80.81.1-1.11.01.0
Locomotion distance, session 82.74.04.8-2.21.81.82.1-2.11.91.9
Degree of sensitization distance1.81.83.81.1-0.2-0.2-1.31.4-1.9-1.9
Degree of sensitization stereotypy6.77.38.8-3.02.42.42.9-2.92.72.7
Conditioned locomotion0.00.10.20.2-0.4-0.4-0.10.00.20.2
Cocaine response after cond. corrected2.52.83.71.8-1.2-1.2-1.81.8-1.9-1.9
Cocaine response after cond. not corrected0.70.81.10.9-0.7-0.7-0.90.9-1.0-1.0
Cocaine response before conditioning2.43.03.8-1.81.11.21.8-1.92.02.0
Saline control response1.72.23.9-1.72.02.01.5-1.30.70.7
Bone: connectivity density0.20.30.7-0.2-0.1-0.10.4-0.50.80.8
Bone: cortical apparent density2.43.24.02.0-1.4-1.4-1.91.9-1.9-1.9
Bone: cortical area0.20.40.8-0.60.90.90.5-0.40.10.1
Bone: cortical porosity1.31.52.1-1.40.70.71.3-1.41.41.4
Bone: cortical porosity1.11.21.9-1.20.60.61.2-1.21.41.4
Bone: cortical thickness0.10.20.30.5-0.5-0.5-0.40.4-0.2-0.2
Bone: cortical thickness0.20.30.4-0.50.30.30.5-0.50.70.7
Bone: cortical tissue density2.43.13.92.0-1.4-1.4-1.91.9-1.8-1.8
Condit. Reinf. active minus inactive responses0.10.20.4-0.30.60.60.2-0.0-0.3-0.3
Condit. Reinf. active-inactive response ratio0.40.41.0-0.61.01.00.5-0.3-0.2-0.2
Condit. Reinf. active responses0.00.00.10.00.20.2-0.10.2-0.3-0.3
Condit. Reinf. inactive responses0.00.00.10.2-0.3-0.3-0.10.1-0.0-0.0
Incentive salience index mean0.10.20.4-0.40.70.70.3-0.2-0.1-0.1
Condit. Reinf. lever presses0.10.10.1-0.30.40.40.3-0.20.10.1
Condit. Reinf. active minus inactive responses6.78.313.2-3.33.63.62.9-2.61.71.7
Condit. Reinf. active-inactive response ratio1.91.92.7-1.61.71.61.4-1.31.01.0
Condit. Reinf. active responses8.111.218.7-3.84.34.33.4-2.91.81.8
Condit. Reinf. inactive responses4.25.29.4-2.63.03.12.3-1.91.01.0
Condit. Reinf. lever presses17.623.932.0-5.55.75.65.1-4.73.53.5
Condit. Reinf. lever reinforcers received9.413.320.9-4.14.64.53.7-3.32.22.2
Conditioned reinforcement - actives3.63.64.5-2.01.51.52.1-2.12.02.0
Conditioned reinforcement - inactives0.30.40.80.7-0.0-0.1-0.60.5-0.9-0.9
Conditioned locomotion3.64.46.0-1.91.41.52.3-2.32.42.4
Patch foraging indifference point 0 sec4.36.99.7-3.12.62.62.9-2.72.22.2
Patch foraging indifference point AUC0.20.20.40.10.50.5-0.20.4-0.6-0.6
Delay disc. indifference point, 0s delay0.60.71.0-1.01.01.00.9-0.80.50.5
Delay disc. indifference point, 16s delay0.10.10.10.2-0.4-0.4-0.10.10.10.1
Delay disc. indifference point, 2s delay0.40.51.0-0.81.01.00.6-0.4-0.1-0.1
Delay disc. indifference point, 24s delay0.90.91.41.0-1.2-1.2-0.90.9-0.6-0.6
Delay disc. indifference point, 4s delay0.50.51.2-0.81.11.10.5-0.3-0.2-0.2
Delay disc. indifference point, 8s delay0.00.00.1-0.3-0.1-0.10.1-0.00.10.1
Indifference point function ln k1.92.74.5-1.60.60.71.7-1.82.12.1
Indifference point function log k1.92.74.5-1.60.60.71.7-1.82.12.1
Patch foraging total patch changes 0 sec3.45.47.7-2.82.42.42.5-2.41.91.9
Patch foraging total patch changes 12 sec0.91.22.9-1.21.71.60.9-0.70.20.2
Patch foraging total patch changes 18 sec2.12.64.3-1.92.02.11.6-1.51.01.0
Patch foraging total patch changes 24 sec0.80.92.5-0.81.51.60.8-0.6-0.0-0.0
Patch foraging total patch changes 6 sec0.71.11.3-1.10.90.91.2-1.01.11.1
Patch foraging time to switch 0 sec3.55.37.72.7-2.8-2.5-2.42.2-1.6-1.6
Patch foraging water rate 0 sec3.45.57.2-2.72.42.32.5-2.42.02.0
Patch foraging water rate 12 sec2.43.74.5-2.11.81.72.0-2.11.91.9
Patch foraging water rate 18 sec1.11.52.7-1.41.61.41.3-1.20.80.8
Patch foraging water rate 24 sec1.82.54.2-1.50.90.61.6-1.72.12.1
Patch foraging water rate 6 sec1.32.02.4-1.41.21.01.4-1.51.61.6
Seeking ratio, delayed vs. immediate footshock1.01.21.91.3-1.4-1.3-1.20.9-0.7-0.7
Distance traveled before self-admin1.31.42.11.1-1.5-1.2-1.21.3-1.0-1.0
Distance traveled after self-admin0.40.51.10.5-1.0-0.9-0.1-0.00.80.8
Extensor digitorum longus weight0.20.92.20.7-0.0-0.0-0.81.0-1.5-1.5
Bone: elastic displacement1.92.13.81.5-2.0-2.0-1.51.3-0.7-0.7
Bone: elastic work1.52.04.01.4-2.0-2.0-1.41.1-0.5-0.5
Bone: endosteal estimation0.81.84.3-1.42.12.11.2-0.90.00.0
Bone: endosteal perimeter1.22.55.2-1.72.32.31.5-1.20.50.5
Epididymis fat weight1.02.24.61.2-0.5-0.4-1.41.6-2.1-2.1
Delta time in closed arm before/after self-admin3.02.95.31.5-0.6-0.4-1.72.0-2.3-2.3
Delta time in open arm before/after self-admin3.83.64.8-2.12.22.12.0-2.01.51.5
Diff in mean of infusions in LGA sessions3.74.15.72.4-1.7-1.9-2.22.2-1.8-1.8
Delay discount exponential model param0.10.10.2-0.20.30.30.3-0.40.40.4
Extinction: sum of active levers before priming0.10.10.20.3-0.4-0.3-0.40.4-0.4-0.4
Active lever presses in extinction session 64.34.27.4-2.10.70.72.1-2.22.72.7
Bone: final force0.00.00.00.2-0.1-0.1-0.20.2-0.2-0.2
Bone: final moment0.00.00.0-0.10.20.20.1-0.0-0.0-0.0
Food consumed during 24 hour testing period4.65.66.7-2.62.02.02.5-2.52.42.4
Glucose0.10.10.2-0.20.0-0.00.3-0.30.40.4
Heart weight1.31.92.4-1.51.31.41.5-1.51.21.2
Delay discount hyperbolic model param0.00.10.10.0-0.0-0.00.1-0.30.40.4
Intermittent access intake day 1-15 change0.90.91.1-0.90.80.81.0-0.91.11.1
Intermittent access intake escalation1.21.11.5-1.10.90.81.1-1.01.21.2
Intermittent access intake escalation 20.20.20.2-0.40.50.50.5-0.20.30.3
Intermitt. access day 1 inactive lever presses0.60.61.00.9-0.3-0.5-0.80.8-1.0-1.0
Intermitt. access day 15 inactive lever presses0.10.20.3-0.20.30.30.4-0.50.50.5
Intermitt. access escalation Index0.40.40.5-0.60.60.60.6-0.60.70.7
Intermittent access day 1 total infusions1.21.32.3-1.31.41.51.1-1.20.50.5
Intermittent access day 15 total infusions2.02.32.6-1.61.51.61.6-1.61.41.4
Intermittent access terminal intake (last 3 days)1.71.82.2-1.41.41.51.5-1.41.11.1
Intermittent access total infusions1.11.32.1-1.11.41.41.2-1.20.60.6
Intermittent access day 1 locomotion0.10.20.3-0.20.20.30.4-0.50.40.4
Intermittent access day 15 total locomotion1.81.92.2-1.31.21.21.5-1.51.51.5
Intermittent access total locomotion0.70.81.1-0.90.91.01.0-1.00.70.7
Intermittent access standard deviation0.00.00.1-0.30.10.30.2-0.1-0.0-0.0
Left kidney weight0.51.43.4-1.21.81.80.9-0.4-0.4-0.4
Right kidney weight0.30.71.8-0.81.31.40.7-0.2-0.4-0.4
Cocaine induced anxiety2.32.63.91.8-2.0-1.7-1.71.6-1.2-1.2
Post-drug Anxiety1.31.41.91.4-0.9-1.0-1.31.3-1.2-1.2
Baseline Anxiety1.01.12.5-1.01.61.31.0-0.90.50.5
Tail length1.23.710.5-1.43.23.10.9-0.2-1.3-1.3
Length with tail0.62.24.6-0.42.22.10.00.5-1.7-1.7
Length without tail0.20.40.60.8-0.7-0.6-0.70.6-0.5-0.5
Times rat made contact with spout0.60.71.30.7-0.3-0.3-0.80.9-1.1-1.1
Lifetime Intake1.51.72.7-1.31.71.61.3-1.40.70.7
Liver weight, left1.21.93.61.3-0.3-0.4-1.31.5-1.9-1.9
Liver weight, right2.64.48.32.0-0.5-0.6-2.12.3-2.9-2.9
Locomotor activity0.81.21.6-1.30.80.71.2-1.11.21.2
Locomotor testing distance1.83.14.3-2.11.91.91.9-1.71.31.3
Locomotor testing rearing0.40.61.6-0.91.21.30.6-0.4-0.0-0.0
Locomotion in novel chamber1.61.94.0-1.20.20.21.5-1.32.02.0
Locomotion in novel chamber post-restriction2.73.34.0-1.81.41.51.9-2.02.02.0
Fecal boli incidents, locomotor time 11.41.52.4-1.30.60.61.3-1.31.51.5
Change in fecal boli incidents, locomotor task1.31.21.91.4-0.9-0.9-1.21.2-1.1-1.1
Time >=10cm from walls, locomotor time 12.42.42.9-1.71.21.21.6-1.71.71.7
Bouts of movement, locomotor time 10.30.40.5-0.60.40.40.6-0.60.70.7
Total resting periods, locomotor time 10.30.40.8-0.40.10.10.5-0.70.90.9
Rest time, locomotor task time 10.10.10.20.1-0.3-0.3-0.0-0.20.40.4
Distance moved, locomotor task time 10.20.20.4-0.10.60.6-0.00.3-0.6-0.6
Vertical activity count, locomotor time 10.20.20.6-0.40.80.80.2-0.1-0.4-0.4
Time >=10cm from walls, locomotor time 21.51.62.2-1.51.51.51.2-1.20.80.8
Bouts of movement, locomotor time 20.20.30.6-0.30.80.80.20.1-0.4-0.4
Total resting periods, locomotor time 20.20.20.40.00.40.4-0.10.4-0.7-0.7
Rest time, locomotor task time 23.33.84.82.2-2.1-2.1-2.21.9-1.5-1.5
Distance moved, locomotor task time 23.13.65.0-2.22.22.22.0-1.81.21.2
Vertical activity count, locomotor time 21.01.12.2-1.21.51.50.9-0.80.10.1
Light reinforcement 12.85.16.22.2-2.5-2.5-2.52.3-1.9-1.9
Light reinforcement 20.30.31.00.3-1.0-1.0-0.50.30.00.0
Bone: marrow area0.71.43.6-1.21.91.91.0-0.7-0.1-0.1
Bone: maximum diameter1.42.54.6-1.82.12.11.6-1.40.60.6
Bone: maximum force0.00.00.0-0.10.20.20.1-0.10.00.0
Bone: maximum moment0.10.10.2-0.40.50.50.4-0.30.20.2
Mean time between licks in bursts3.44.710.4-2.43.23.22.0-1.60.20.2
Mean num. licks in bursts4.85.87.1-2.72.22.22.5-2.52.32.3
Cd content in liver0.90.91.60.9-0.5-0.3-1.01.1-1.2-1.2
Co content in liver1.11.32.8-1.21.71.71.0-0.90.30.3
Cu content in liver0.60.71.8-0.81.31.30.6-0.4-0.2-0.2
Fe content in liver0.10.10.10.3-0.1-0.1-0.30.3-0.3-0.3
K content in liver0.40.40.60.6-0.3-0.3-0.60.7-0.8-0.8
Mg content in liver0.10.10.2-0.40.50.40.3-0.30.10.1
Mn content in liver1.11.22.91.2-1.7-1.7-1.00.8-0.1-0.1
Na content in liver0.30.30.4-0.60.40.40.6-0.60.50.5
Rb content in liver0.70.91.5-1.11.21.10.9-0.90.60.6
Se content in liver3.44.15.62.4-2.4-2.4-2.11.9-1.4-1.4
Sr content in liver0.10.10.3-0.1-0.2-0.20.1-0.30.50.5
Zn content in liver4.95.47.1-2.72.62.62.5-2.31.71.7
Bone: minimum diameter0.40.71.5-0.31.21.20.10.2-1.0-1.0
Time in familiar zone, hab. session 10.10.10.10.20.20.2-0.20.2-0.4-0.4
Time in novel zone, hab. session 10.30.30.30.5-0.6-0.6-0.50.5-0.5-0.5
Total zone transitions, hab. session 10.20.20.5-0.2-0.2-0.20.3-0.40.70.7
Total locomotion distance, hab. session 11.21.83.31.2-0.4-0.4-1.31.5-1.8-1.8
Locomotion velocity, hab. session 10.71.01.90.9-0.2-0.2-1.01.1-1.4-1.4
Time in familiar zone, hab. session 21.41.42.2-1.31.51.51.3-1.10.70.7
Time in novel zone, hab. session 20.30.30.60.5-0.8-0.8-0.50.4-0.1-0.1
Total zone transitions, hab. session 21.82.33.0-1.61.11.11.6-1.71.71.7
Total locomotion distance, hab. session 20.40.51.10.20.50.5-0.40.6-1.1-1.1
Locomotion velocity, hab. session 20.50.71.80.40.40.4-0.60.8-1.3-1.3
Novel to familiar place preference ratio0.10.10.1-0.40.30.30.3-0.30.30.3
Novelty place preference0.10.10.1-0.40.30.30.3-0.30.30.3
Time in novel zone, NPP test0.30.30.4-0.60.40.40.5-0.50.50.5
Total zone transitions, NPP test0.40.51.0-0.60.30.30.7-0.81.01.0
Total locomotion distance, NPP test0.71.01.90.9-0.1-0.1-1.01.1-1.4-1.4
Locomotion velocity, NPP test1.11.62.71.3-0.5-0.5-1.31.4-1.6-1.6
Intraocular pressure0.40.61.3-0.60.10.20.8-0.81.21.2
Delta distance traveled before/after self-admin1.71.82.5-1.01.11.11.4-1.61.51.5
Delta ambulatory time before/after self-admin1.82.03.1-1.11.00.91.4-1.71.81.8
Parametrial fat weight1.42.74.41.4-0.8-0.9-1.81.8-2.1-2.1
Pavlov. Cond. lever latency1.21.52.11.4-1.4-1.4-1.41.2-0.9-0.9
Pavlov. Cond. magazine entry latency2.83.64.9-2.22.22.22.0-1.81.21.2
Pavlov. Cond. change in total contacts1.41.52.1-1.41.41.41.3-1.20.80.8
Pavlov. Cond. index score2.83.54.8-2.22.22.22.0-1.81.21.2
Pavlov. Cond. latency score2.73.54.8-2.22.12.12.0-1.81.21.2
Pavlov. Cond. lever contacts1.11.32.0-1.31.41.41.2-1.00.60.6
Pavlov. Cond. magazine entry number3.54.35.82.4-2.3-2.3-2.22.1-1.5-1.5
Pavlov. Cond. intertrial magazine entries0.91.11.51.2-1.2-1.2-1.11.0-0.7-0.7
Pavlov. Cond. lever-magazine prob. diff.2.32.83.8-1.92.02.01.8-1.61.11.1
Pavlov. Cond. response bias1.11.32.0-1.31.41.41.2-1.10.60.6
Pavlov. Cond. lever latency18.524.931.95.6-5.5-5.5-5.34.9-3.8-3.8
Pavlov. Cond. magazine entry latency4.75.46.7-2.62.22.22.5-2.42.22.2
Pavlov. Cond. change in total contacts14.720.325.4-5.04.84.84.8-4.53.73.7
Pavlov. Cond. index score14.618.823.8-4.94.74.74.6-4.33.43.4
Pavlov. Cond. latency score13.316.520.8-4.64.44.44.3-4.03.33.3
Pavlov. Cond. lever contacts19.226.233.4-5.85.75.75.4-5.03.93.9
Pavlov. Cond. magazine entry number8.510.312.63.5-3.1-3.1-3.43.3-3.0-3.0
Pavlov. Cond. intertrial magazine entries0.40.61.50.20.40.4-0.40.6-1.2-1.2
Pavlov. Cond. lever-magazine prob. diff.13.517.221.9-4.74.64.64.4-4.13.23.2
Pavlov. Cond. response bias19.726.834.0-5.85.65.65.5-5.14.14.1
Time in closed arm before self-admin3.53.97.1-1.70.70.72.1-2.32.72.7
Time in closed arm after self-admin0.60.61.90.9-1.4-1.1-0.60.40.20.2
Time in open arm before self-admin4.85.26.92.3-2.0-2.1-2.52.6-2.2-2.2
Time in open arm after self-admin0.30.40.9-0.40.90.80.10.2-0.6-0.6
Bone: periosteal estimation0.81.63.6-1.31.91.91.1-0.90.10.1
Bone: periosteal perimeter1.01.73.2-1.51.81.81.3-1.00.50.5
Bone: post-yield work0.20.20.3-0.50.50.50.5-0.50.40.4
Progressive ratio test 1 active lever presses0.10.10.30.5-0.2-0.2-0.40.3-0.4-0.4
Progressive ratio test 1 breakpoint0.10.20.30.5-0.1-0.1-0.40.3-0.5-0.5
Progressive ratio test 1 inactive lever presses0.30.30.8-0.50.90.80.3-0.5-0.3-0.3
Progressive ratio test 2 active lever presses0.80.91.5-1.11.21.21.0-0.80.50.5
Progressive ratio test 2 breakpoint0.81.01.6-1.11.31.21.0-0.80.50.5
Progressive ratio test 2 inactive lever presses0.91.11.5-1.21.01.01.1-1.20.80.8
Incentive Sensitization - Responses2.12.13.4-1.71.81.71.5-1.20.90.9
Incentive Sensitization - Breakpoint2.02.02.9-1.71.71.61.6-1.31.01.0
Sum of active levers in priming session hrs 5-60.20.20.4-0.1-0.6-0.7-0.10.10.40.4
Progressive ratio0.10.10.3-0.4-0.2-0.10.3-0.40.50.5
Food seeking constrained by brief footshock0.60.71.4-1.11.11.20.9-0.50.10.1
Seeking ratio, punishment vs. effort0.50.61.6-0.51.31.20.4-0.1-0.5-0.5
Retroperitoneal fat weight5.217.030.63.8-1.6-1.6-4.24.5-5.5-5.5
Reaction time number correct0.60.82.0-0.5-0.3-0.60.6-0.71.41.4
Reaction time mean minus median0.50.71.4-1.11.01.20.8-0.70.30.3
Reaction time mean minus median AUC1.11.52.2-1.51.11.21.2-1.31.11.1
Reaction time num false alarms2.53.43.92.0-1.7-1.6-1.92.0-1.9-1.9
Reaction time num false alarms AUC1.31.82.01.4-1.4-1.3-1.41.4-1.3-1.3
Reaction time trials correct on left0.60.82.0-0.5-0.3-0.60.6-0.71.41.4
Reaction time trials on left0.60.82.0-0.5-0.4-0.60.6-0.71.41.4
Reaction time mean1.01.52.11.2-0.9-0.8-1.31.3-1.5-1.5
Reaction time mean AUC1.31.82.21.4-1.1-1.0-1.51.4-1.5-1.5
Median of all reaction times1.82.42.81.7-1.3-1.3-1.61.6-1.7-1.7
Reaction time omissions0.40.60.80.6-0.7-0.5-0.80.8-0.9-0.9
Reaction time false alarm rate1.92.73.71.7-1.2-1.0-1.71.8-1.9-1.9
Reaction time premature initiation rate0.91.23.7-0.91.71.90.7-0.4-0.5-0.5
Reaction time premature initiations0.81.22.3-1.21.41.51.1-0.90.40.4
Std. dev. reaction times0.20.30.6-0.10.60.8-0.00.2-0.8-0.8
Reaction time trials completed0.60.82.0-0.5-0.4-0.60.6-0.71.41.4
Reaction time trials AUC0.50.71.6-0.5-0.3-0.50.6-0.71.31.3
Run reversals in cocaine runway, females2.72.76.51.00.30.1-1.41.6-2.5-2.5
Run reversals in cocaine runway, males0.10.10.10.3-0.3-0.3-0.30.1-0.2-0.2
Latency to leave start box in cocaine runway3.74.05.42.1-1.2-1.3-2.22.2-2.3-2.3
Latency to leave start box in cocaine runway, F3.53.86.31.9-0.9-0.9-2.12.2-2.5-2.5
Latency to leave start box in cocaine runway, M0.20.20.50.6-0.7-0.7-0.50.3-0.0-0.0
Std. dev. time between licks in bursts0.91.02.6-0.81.61.60.6-0.2-0.6-0.6
Total sessions with >9 infusions3.13.44.2-1.92.02.01.9-2.01.51.5
Short access day 1 total inactive lever presses0.10.10.30.50.0-0.2-0.50.2-0.4-0.4
Short access day 10 total inactive lever presses0.10.10.30.4-0.4-0.6-0.10.20.10.1
Short access day 1 total infusions2.52.74.2-1.92.02.01.7-1.60.90.9
Short access day 10 total infusions1.21.42.8-1.21.71.61.2-1.10.40.4
Short access total infusions1.11.22.6-1.21.61.50.9-1.00.20.2
Short access day 1 locomotion2.42.63.4-1.71.21.21.6-1.91.81.8
Short access day 10 total locomotion0.30.30.6-0.50.60.50.8-0.50.50.5
Short access total locomotion0.20.20.2-0.40.40.50.5-0.50.30.3
One hour access (0.3 mA shock)2.22.63.6-1.71.91.81.8-1.61.21.2
Compulsive drug intake0.20.20.4-0.1-0.4-0.50.1-0.30.60.6
One hour access (shock baseline)1.61.93.1-1.41.81.71.5-1.30.90.9
Social response proportion0.60.60.90.9-0.3-0.4-0.80.9-0.9-0.9
Social responses0.91.12.41.0-0.0-0.1-1.01.1-1.5-1.5
Social time2.53.34.72.0-2.0-2.2-2.01.7-1.2-1.2
Soleus weight0.61.74.10.70.40.4-1.01.3-2.0-2.0
Bone: stiffness0.40.61.00.9-0.2-0.2-0.70.8-1.0-1.0
Tibialis anterior weight0.10.20.5-0.30.60.70.10.1-0.5-0.5
Time to tail flick, vehicle, before self-admin0.10.10.20.1-0.4-0.40.0-0.00.50.5
Time to tail flick, vehicle, after self-admin3.03.34.1-1.91.61.81.8-2.01.71.7
Time to tail flick, test, before self-admin0.30.30.6-0.50.80.80.4-0.3-0.3-0.3
Time to tail flick, test, after self-admin0.30.31.2-0.21.10.90.10.1-0.4-0.4
Delta time to tail flick, vehicle, before/after SA1.81.82.6-1.61.41.61.2-1.50.90.9
Delta time to tail flick, test, before/after SA0.30.30.50.7-0.3-0.4-0.60.6-0.4-0.4
Tibia length2.36.57.9-2.71.91.92.7-2.82.82.8
Ambulatory time before self-admin1.21.32.11.2-1.4-1.3-1.11.2-0.8-0.8
Ambulatory time after self-admin0.60.61.50.3-0.9-0.60.2-0.51.21.2
Bone: tissue strength0.40.40.80.0-0.8-0.80.1-0.30.90.9
Total heroin consumption0.40.50.7-0.80.40.40.7-0.80.80.8
Bone: trabecular number0.60.91.91.1-1.4-1.4-0.80.7-0.1-0.1
Bone: trabecular spacing0.91.21.6-1.31.21.21.1-1.10.90.9
Bone: trabecular thickness0.30.40.40.6-0.6-0.6-0.60.6-0.6-0.6
Bone: trabecular tissue density2.23.15.31.6-0.8-0.8-1.82.0-2.3-2.3
Water consumed over 24 hours0.50.61.00.9-1.0-1.0-0.80.7-0.3-0.3
Number of responses in last shaping day0.10.20.4-0.40.60.60.3-0.2-0.1-0.1