Pgm2l1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	pVTA	gene expression	Pgm2l1	0.09	0.07	4.8e-05	0.01	0.04	0.05	0.03	2.0e-02	5.1e-04	1.3e-04	2.1e-03
2	BLA	gene expression	Pgm2l1	0.45	0.16	0.0e+00	0.28	0.35	0.36	0.37	3.6e-15	3.0e-19	4.7e-20	1.4e-20
3	Adipose	gene expression	Pgm2l1	0.14	0.09	3.0e-09	0.07	0.06	0.05	0.07	3.6e-08	8.9e-07	1.1e-06	5.8e-08
4	NAcc	gene expression	Pgm2l1	0.31	0.15	0.0e+00	0.18	0.17	0.18	0.17	3.8e-26	9.5e-26	7.3e-26	1.0e-25
5	Brain	gene expression	Pgm2l1	0.58	0.17	0.0e+00	0.35	0.52	0.52	0.52	1.4e-33	2.2e-55	1.7e-55	1.8e-55
6	IC	gene expression	Pgm2l1	0.52	0.13	0.0e+00	0.22	0.42	0.41	0.41	9.2e-10	8.1e-19	1.4e-18	2.0e-18
7	IL	mRNA stability	Pgm2l1	0.16	0.12	9.7e-03	-0	-0.01	-0.01	0.03	4.0e-01	5.5e-01	9.4e-01	5.6e-02
8	PL	gene expression	Pgm2l1	0.31	0.14	0.0e+00	0.28	0.34	0.33	0.33	1.5e-30	1.1e-37	1.3e-36	2.1e-37
9	OFC	gene expression	Pgm2l1	0.58	0.17	2.4e-12	0.33	0.33	0.32	0.34	1.1e-08	1.6e-08	1.7e-08	6.7e-09
10	IL	gene expression	Pgm2l1	0.66	0.17	1.0e-10	0.16	0.17	0.18	0.18	9.8e-05	7.3e-05	4.3e-05	4.4e-05
11	Adipose	mRNA stability	Pgm2l1	0.03	0.03	6.7e-03	0.01	0	0	0	1.6e-02	2.1e-01	1.4e-01	1.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	0.2	0.3	1.1	-0.5	0.4	-0.9	-0.8	-0.3	0.3	0.2	0.2	-0.2	0.2	1.0
Area under the delay curve	0.0	0.1	0.2	-0.4	0.0	-0.1	-0.1	-0.1	0.1	0.1	0.3	0.4	-0.3	-0.3
BMI with tail	0.3	1.2	4.5	-0.0	0.4	0.7	0.9	-0.7	0.4	0.9	0.7	1.8	-1.5	-2.1
BMI without tail	0.3	1.7	8.0	0.8	-0.3	1.7	1.8	0.0	-0.3	0.3	0.1	1.5	-1.2	-2.8
Body weight	0.5	2.1	10.3	0.3	0.1	1.5	1.5	-0.5	0.2	0.7	0.7	2.0	-1.8	-3.2
Weight adjusted by age	0.1	0.2	0.8	-0.1	-0.4	0.6	0.6	0.2	-0.2	-0.2	-0.0	0.3	-0.2	-0.9
Bone surface	0.5	1.0	1.4	1.2	-1.1	1.1	1.1	1.1	-1.0	-1.0	-1.0	-0.8	0.7	-0.6
Bone volume	0.2	0.4	0.5	0.7	-0.7	0.6	0.7	0.7	-0.7	-0.7	-0.6	-0.5	0.5	-0.2
Breakpoint value in progressive ratio session	0.5	0.9	2.2	-1.1	0.7	-1.5	-1.5	-0.7	0.8	0.5	0.6	0.1	-0.2	1.3
Number of licking bursts	2.2	6.6	8.1	-2.8	2.8	-2.4	-2.4	-2.8	2.8	2.8	2.8	2.6	-2.6	0.1
Context. condit. distance diff. score	2.8	3.4	4.3	2.0	-2.0	1.7	1.6	2.0	-2.0	-2.0	-2.1	-1.9	1.9	0.3
Locomotion velocity, session 1	0.3	0.3	1.5	-0.3	0.3	-0.8	-0.8	-0.1	0.2	0.1	-0.0	-0.5	0.4	1.2
Locomotion distance, session 1	1.1	1.4	2.1	1.2	-1.2	0.7	0.7	1.3	-1.2	-1.3	-1.3	-1.4	1.4	0.5
Locomotion velocity, session 2	0.1	0.1	0.1	0.3	-0.3	0.2	0.3	0.3	-0.3	-0.3	-0.2	-0.2	0.1	-0.3
Locomotion distance, session 2	0.6	0.8	1.0	1.0	-1.0	0.7	0.7	1.0	-1.0	-1.0	-1.0	-1.0	1.0	0.1
Locomotion velocity, session 3	1.0	1.2	1.9	1.0	-1.1	0.5	0.6	1.2	-1.1	-1.2	-1.2	-1.4	1.4	0.8
Locomotion distance, session 3	1.7	1.9	3.2	1.3	-1.4	0.7	0.7	1.5	-1.4	-1.5	-1.6	-1.7	1.8	1.0
Stereotopy head waving bouts, day 3	0.6	0.7	1.2	-0.8	0.8	-0.3	-0.4	-0.9	0.9	0.9	1.0	1.0	-1.1	-0.6
Stereotopy head waving duration, day 3	0.1	0.2	0.3	0.4	-0.5	0.3	0.3	0.4	-0.4	-0.5	-0.5	-0.6	0.5	0.2
Locomotion velocity, session 7	0.2	0.2	0.5	-0.4	0.4	-0.6	-0.6	-0.4	0.4	0.2	0.3	-0.1	-0.1	0.7
Locomotion distance, session 7	0.1	0.2	0.2	-0.5	0.5	-0.4	-0.4	-0.5	0.5	0.3	0.5	0.2	-0.4	0.1
Stereotopy head waving bouts, day 7	3.1	3.6	4.6	2.0	-2.1	1.7	1.7	2.1	-2.1	-2.0	-2.1	-1.8	2.0	0.2
Stereotopy head waving duration, day 7	3.3	4.1	5.4	2.2	-2.3	1.9	2.0	2.2	-2.3	-2.1	-2.2	-1.8	1.9	-0.3
Locomotion velocity, session 8	0.9	1.0	1.4	1.1	-1.1	0.9	0.9	1.1	-1.1	-1.2	-1.1	-1.1	1.0	-0.0
Locomotion distance, session 8	2.7	4.0	5.0	2.2	-2.2	2.0	1.8	2.2	-2.2	-2.2	-2.2	-2.0	1.9	-0.1
Degree of sensitization distance	1.6	1.7	3.5	-1.0	1.1	-0.1	-0.2	-1.3	1.2	1.2	1.5	1.8	-1.9	-1.6
Degree of sensitization stereotypy	6.3	7.0	9.0	2.9	-3.0	2.4	2.4	3.0	-3.0	-2.8	-3.0	-2.6	2.7	-0.0
Conditioned locomotion	0.1	0.1	0.7	-0.2	0.1	-0.5	-0.5	0.0	0.1	-0.1	-0.1	-0.4	0.4	0.8
Cocaine response after cond. corrected	1.8	2.7	3.4	-1.8	1.7	-1.3	-1.3	-1.9	1.8	1.8	1.8	1.9	-1.8	-0.4
Cocaine response after cond. not corrected	0.4	0.6	0.9	-0.9	0.8	-0.6	-0.7	-0.9	0.9	0.9	0.9	0.9	-0.9	-0.1
Cocaine response before conditioning	2.6	3.1	4.2	1.8	-1.9	1.3	1.3	2.0	-1.9	-1.9	-2.0	-2.0	2.0	0.7
Saline control response	1.4	1.9	3.1	1.5	-1.6	1.8	1.7	1.3	-1.4	-1.4	-1.2	-0.8	0.8	-1.1
Bone: connectivity density	0.2	0.2	1.1	0.1	-0.1	-0.5	-0.4	0.2	-0.1	-0.3	-0.3	-0.7	0.7	1.1
Bone: cortical apparent density	1.8	2.8	3.7	-1.8	1.9	-1.6	-1.6	-1.9	1.9	1.8	1.9	1.5	-1.6	0.2
Bone: cortical area	0.1	0.2	0.8	0.4	-0.4	0.6	0.7	0.3	-0.2	-0.3	-0.1	0.0	-0.2	-0.9
Bone: cortical porosity	0.9	1.0	2.0	0.9	-1.1	0.5	0.4	1.0	-1.0	-1.2	-1.1	-1.4	1.2	0.9
Bone: cortical porosity	1.1	1.2	2.1	1.0	-1.2	0.6	0.5	1.1	-1.1	-1.3	-1.2	-1.4	1.3	0.8
Bone: cortical thickness	0.3	0.4	0.7	-0.7	0.7	-0.9	-0.9	-0.7	0.7	0.5	0.7	0.2	-0.4	0.6
Bone: cortical thickness	0.2	0.2	0.5	0.5	-0.5	0.3	0.3	0.5	-0.5	-0.7	-0.5	-0.7	0.5	0.2
Bone: cortical tissue density	1.7	2.7	3.6	-1.8	1.9	-1.7	-1.6	-1.8	1.8	1.7	1.8	1.4	-1.5	0.3
Condit. Reinf. active minus inactive responses	0.2	0.2	0.9	0.3	-0.3	0.6	0.6	0.1	-0.2	-0.2	-0.0	0.2	-0.3	-0.9
Condit. Reinf. active-inactive response ratio	0.4	0.4	1.5	0.6	-0.6	1.0	1.0	0.4	-0.5	-0.4	-0.3	0.1	-0.1	-1.2
Condit. Reinf. active responses	0.0	0.0	0.3	0.0	0.0	0.2	0.2	-0.1	0.1	0.0	0.2	0.2	-0.3	-0.5
Condit. Reinf. inactive responses	0.0	0.0	0.1	-0.2	0.2	-0.3	-0.3	-0.1	0.1	0.1	0.1	-0.1	0.0	0.3
Incentive salience index mean	0.2	0.2	0.8	0.5	-0.4	0.7	0.7	0.3	-0.3	-0.4	-0.2	-0.0	-0.1	-0.9
Condit. Reinf. lever presses	0.2	0.3	0.4	0.6	-0.6	0.5	0.6	0.5	-0.5	-0.6	-0.4	-0.4	0.3	-0.4
Condit. Reinf. active minus inactive responses	5.5	8.4	13.3	3.4	-3.2	3.6	3.6	3.0	-3.0	-2.9	-2.7	-1.7	1.7	-2.3
Condit. Reinf. active-inactive response ratio	1.1	1.7	2.4	1.5	-1.5	1.5	1.6	1.4	-1.4	-1.3	-1.3	-0.9	0.9	-0.8
Condit. Reinf. active responses	8.2	11.7	19.2	3.9	-3.8	4.3	4.4	3.4	-3.5	-3.3	-3.0	-1.9	1.9	-3.0
Condit. Reinf. inactive responses	3.8	5.7	9.9	2.7	-2.6	3.1	3.1	2.3	-2.4	-2.3	-2.0	-1.1	1.2	-2.4
Condit. Reinf. lever presses	16.0	23.2	32.3	5.6	-5.4	5.7	5.7	5.0	-5.1	-5.0	-4.7	-3.4	3.4	-2.9
Condit. Reinf. lever reinforcers received	9.6	13.5	21.4	4.2	-4.1	4.6	4.6	3.7	-3.8	-3.6	-3.3	-2.1	2.1	-3.1
Conditioned reinforcement - actives	0.6	2.5	3.5	1.9	-1.7	1.2	1.4	1.8	-1.8	-1.7	-1.8	-1.8	1.6	0.3
Conditioned reinforcement - inactives	0.1	0.3	0.4	-0.7	0.6	-0.5	-0.6	-0.5	0.4	0.6	0.4	0.3	-0.4	0.4
Conditioned locomotion	2.9	4.3	6.6	2.2	-1.9	1.3	1.3	2.4	-2.2	-2.1	-2.4	-2.6	2.6	1.1
Patch foraging indifference point 0 sec	2.1	6.0	8.7	2.6	-2.9	2.6	2.5	2.7	-2.7	-2.7	-2.6	-2.1	2.1	-0.8
Patch foraging indifference point AUC	0.1	0.3	1.5	0.0	-0.1	0.5	0.6	-0.2	0.1	0.1	0.3	0.6	-0.7	-1.2
Delay disc. indifference point, 0s delay	1.0	1.2	1.6	1.1	-1.3	1.3	1.3	1.2	-1.2	-1.1	-1.0	-0.6	0.7	-0.9
Delay disc. indifference point, 16s delay	0.0	0.1	0.2	-0.4	0.2	-0.4	-0.4	-0.1	0.2	0.2	0.2	0.1	-0.0	0.3
Delay disc. indifference point, 2s delay	0.5	0.6	1.5	0.9	-0.8	1.1	1.1	0.6	-0.7	-0.5	-0.4	0.2	0.0	-1.2
Delay disc. indifference point, 24s delay	0.7	1.1	1.7	-1.3	1.1	-1.3	-1.3	-1.0	1.1	1.0	1.0	0.7	-0.7	0.6
Delay disc. indifference point, 4s delay	0.8	0.9	2.8	0.8	-1.0	1.3	1.3	0.7	-0.7	-0.7	-0.4	0.1	-0.1	-1.7
Delay disc. indifference point, 8s delay	0.0	0.0	0.2	-0.5	-0.2	-0.1	-0.1	0.0	-0.0	-0.1	0.1	0.2	-0.1	-0.1
Indifference point function ln k	0.9	2.7	5.0	1.5	-1.6	0.7	0.8	1.9	-1.7	-1.8	-1.9	-2.1	2.2	1.2
Indifference point function log k	0.9	2.7	5.0	1.5	-1.6	0.7	0.8	1.9	-1.7	-1.8	-1.9	-2.1	2.2	1.2
Patch foraging total patch changes 0 sec	1.7	4.9	7.1	2.4	-2.7	2.4	2.3	2.4	-2.4	-2.4	-2.3	-1.8	1.8	-0.9
Patch foraging total patch changes 12 sec	0.8	1.1	2.8	1.0	-1.2	1.5	1.4	0.8	-0.8	-1.0	-0.5	-0.2	0.1	-1.7
Patch foraging total patch changes 18 sec	1.2	2.8	5.0	1.9	-2.0	2.1	2.2	1.6	-1.8	-1.6	-1.5	-0.8	0.9	-1.4
Patch foraging total patch changes 24 sec	0.3	0.9	2.5	1.1	-0.8	1.6	1.4	0.7	-0.8	-0.6	-0.5	0.0	-0.1	-1.6
Patch foraging total patch changes 6 sec	0.7	1.1	1.6	1.1	-1.2	1.0	1.0	1.2	-1.1	-1.3	-1.0	-1.1	0.9	-0.4
Patch foraging time to switch 0 sec	1.3	5.0	7.2	-2.3	2.7	-2.7	-2.5	-2.4	2.4	2.4	2.2	1.6	-1.7	1.2
Patch foraging water rate 0 sec	1.3	5.1	7.0	2.4	-2.6	2.4	2.2	2.5	-2.5	-2.4	-2.3	-1.9	2.0	-0.7
Patch foraging water rate 12 sec	0.8	3.4	4.2	2.0	-2.0	1.8	1.6	2.0	-2.0	-2.0	-2.0	-2.0	1.9	0.2
Patch foraging water rate 18 sec	0.7	1.5	2.7	1.5	-1.3	1.6	1.4	1.3	-1.3	-1.2	-1.2	-0.9	0.8	-0.7
Patch foraging water rate 24 sec	1.7	2.4	4.2	1.5	-1.5	0.8	0.8	1.6	-1.6	-1.7	-1.7	-2.0	2.0	1.0
Patch foraging water rate 6 sec	1.1	1.6	2.2	1.4	-1.4	1.1	0.9	1.4	-1.4	-1.4	-1.4	-1.5	1.5	0.4
Seeking ratio, delayed vs. immediate footshock	1.0	1.4	2.1	-0.9	1.4	-1.4	-1.3	-1.4	1.2	1.2	0.9	0.5	-0.8	1.3
Distance traveled before self-admin	0.5	1.0	1.7	-1.0	1.0	-1.3	-1.0	-1.1	1.1	0.8	1.1	0.8	-0.9	0.2
Distance traveled after self-admin	0.4	0.8	3.6	-0.2	0.6	-1.4	-1.2	-0.3	0.4	0.3	0.0	-0.5	0.6	1.9
Extensor digitorum longus weight	0.3	1.2	2.9	-0.7	0.8	-0.0	0.0	-1.0	0.9	1.0	1.2	1.6	-1.6	-1.7
Bone: elastic displacement	1.7	2.2	4.2	-1.7	1.6	-2.0	-2.0	-1.4	1.5	1.3	1.3	0.6	-0.7	1.5
Bone: elastic work	1.7	2.2	4.4	-1.7	1.5	-2.1	-2.1	-1.4	1.5	1.2	1.2	0.4	-0.6	1.7
Bone: endosteal estimation	0.9	2.3	6.4	1.6	-1.4	2.2	2.3	1.2	-1.2	-1.0	-0.9	0.1	0.0	-2.5
Bone: endosteal perimeter	1.2	3.0	6.2	1.9	-1.7	2.4	2.5	1.5	-1.5	-1.4	-1.2	-0.4	0.3	-2.4
Epididymis fat weight	0.3	1.4	2.4	-1.2	1.2	-0.9	-0.7	-1.4	1.2	1.4	1.2	1.5	-1.4	-0.3
Delta time in closed arm before/after self-admin	3.0	2.8	5.5	-1.3	1.7	-0.8	-0.7	-1.9	1.7	1.8	1.9	2.2	-2.3	-1.2
Delta time in open arm before/after self-admin	2.0	2.4	3.9	1.8	-1.8	2.0	1.9	1.5	-1.7	-1.5	-1.5	-1.0	1.0	-0.9
Diff in mean of infusions in LGA sessions	3.4	6.0	8.3	-2.6	2.9	-2.4	-2.7	-2.7	2.7	2.7	2.5	2.0	-2.1	1.1
Delay discount exponential model param	0.0	0.1	0.2	0.4	-0.0	0.1	0.1	0.1	-0.2	-0.1	-0.3	-0.4	0.3	0.3
Extinction: sum of active levers before priming	0.0	0.0	0.2	-0.1	-0.1	0.1	0.2	-0.0	-0.0	0.2	0.0	0.4	-0.3	-0.4
Active lever presses in extinction session 6	3.7	3.7	8.1	1.2	-1.9	0.2	0.3	2.1	-1.9	-2.1	-2.1	-2.6	2.9	1.9
Bone: final force	0.1	0.1	0.2	-0.4	0.3	-0.4	-0.4	-0.4	0.4	0.3	0.4	0.2	-0.3	0.2
Bone: final moment	0.0	0.0	0.0	-0.2	0.1	-0.2	-0.2	-0.2	0.2	0.1	0.2	0.0	-0.2	0.0
Food consumed during 24 hour testing period	2.5	5.1	6.4	2.5	-2.5	2.0	2.0	2.5	-2.5	-2.5	-2.5	-2.3	2.3	-0.0
Glucose	0.0	0.0	0.1	-0.1	0.2	-0.2	-0.1	-0.1	0.2	0.2	0.2	0.2	-0.1	-0.1
Heart weight	0.9	1.4	2.1	1.4	-1.2	1.0	1.3	1.3	-1.3	-1.2	-1.3	-1.0	1.0	-0.3
Delay discount hyperbolic model param	0.1	0.1	0.3	0.3	0.1	-0.1	-0.1	0.1	-0.1	-0.1	-0.3	-0.5	0.4	0.6
Intermittent access intake day 1-15 change	0.2	1.1	2.1	1.0	-1.1	0.7	0.6	1.1	-1.0	-1.3	-1.0	-1.5	1.3	0.4
Intermittent access intake escalation	0.3	1.4	2.5	1.2	-1.3	0.8	0.8	1.3	-1.2	-1.5	-1.2	-1.6	1.4	0.4
Intermittent access intake escalation 2	0.6	1.1	1.7	1.1	-1.1	1.0	0.8	1.2	-1.0	-1.3	-0.9	-1.2	1.1	-0.1
Intermitt. access day 1 inactive lever presses	0.2	2.1	3.3	-1.5	1.8	-1.2	-1.3	-1.5	1.5	1.7	1.5	1.4	-1.5	-0.1
Intermitt. access day 15 inactive lever presses	0.1	0.7	1.5	-0.9	1.0	-1.2	-1.0	-0.6	0.7	0.8	0.5	0.2	-0.2	1.1
Intermitt. access escalation Index	0.0	0.0	0.1	0.3	-0.0	0.2	0.2	0.3	-0.2	-0.0	-0.2	-0.1	0.3	-0.1
Intermittent access day 1 total infusions	0.6	1.8	2.9	1.7	-1.5	1.4	1.5	1.3	-1.5	-1.2	-1.6	-1.2	1.1	-0.1
Intermittent access day 15 total infusions	1.0	2.6	3.3	1.8	-1.7	1.4	1.4	1.7	-1.7	-1.7	-1.8	-1.8	1.6	0.3
Intermittent access terminal intake (last 3 days)	1.8	3.2	4.1	1.9	-2.0	1.6	1.6	2.0	-2.0	-2.0	-1.9	-1.9	1.7	-0.0
Intermittent access total infusions	1.9	2.3	3.4	1.8	-1.6	1.8	1.8	1.6	-1.7	-1.4	-1.6	-1.2	1.1	-0.4
Intermittent access day 1 locomotion	0.2	0.4	0.9	0.7	-0.4	0.2	0.5	0.6	-0.7	-0.6	-0.8	-0.9	0.7	0.4
Intermittent access day 15 total locomotion	0.5	1.9	3.7	1.3	-1.3	0.7	0.8	1.4	-1.4	-1.5	-1.6	-1.9	1.7	0.8
Intermittent access total locomotion	0.9	1.1	1.6	1.2	-1.1	0.9	1.0	1.1	-1.2	-1.1	-1.3	-1.2	1.0	0.3
Intermittent access standard deviation	0.0	0.2	1.0	0.3	-0.4	0.5	0.7	0.3	-0.2	-0.4	-0.1	0.1	-0.1	-1.0
Left kidney weight	0.1	0.9	4.9	0.3	-0.3	1.1	1.1	-0.1	-0.1	-0.0	0.3	0.9	-0.9	-2.2
Right kidney weight	0.2	1.4	7.6	0.6	-0.4	1.6	1.5	0.0	-0.2	-0.0	0.3	1.0	-1.1	-2.8
Cocaine induced anxiety	0.8	2.1	3.5	-1.8	1.6	-1.9	-1.7	-1.4	1.5	1.4	1.4	0.9	-1.0	0.8
Post-drug Anxiety	2.3	2.6	3.6	-1.8	1.9	-1.8	-1.7	-1.7	1.7	1.8	1.7	1.4	-1.4	0.5
Baseline Anxiety	0.1	0.2	0.6	0.4	-0.3	0.8	0.6	0.2	-0.3	-0.1	-0.3	0.1	-0.0	-0.5
Tail length	0.4	2.3	11.9	0.9	-0.6	2.2	2.1	0.2	-0.3	-0.0	0.2	1.4	-1.3	-3.4
Length with tail	0.4	1.6	8.1	0.7	-0.5	1.9	1.7	-0.0	-0.2	-0.0	0.2	1.1	-1.1	-2.8
Length without tail	0.1	0.3	0.5	-0.5	0.6	-0.3	-0.3	-0.7	0.6	0.6	0.6	0.6	-0.7	-0.2
Times rat made contact with spout	0.6	0.6	1.2	-0.7	0.7	-0.3	-0.3	-0.8	0.8	0.8	0.9	1.1	-1.1	-0.7
Lifetime Intake	2.2	2.7	4.2	2.1	-1.8	2.0	1.9	1.7	-1.8	-1.5	-1.8	-1.3	1.2	-0.3
Liver weight, left	0.4	0.7	2.3	-0.3	0.5	0.3	0.3	-0.7	0.6	0.7	0.8	1.2	-1.3	-1.5
Liver weight, right	1.6	2.8	5.5	-1.3	1.5	-0.3	-0.4	-1.7	1.6	1.7	1.9	2.3	-2.3	-1.8
Locomotor activity	0.7	1.1	2.0	0.8	-1.2	0.7	0.7	1.2	-1.2	-1.4	-1.1	-1.3	1.2	-0.0
Locomotor testing distance	1.0	2.4	3.3	1.6	-1.8	1.7	1.8	1.7	-1.6	-1.7	-1.4	-1.1	1.0	-1.2
Locomotor testing rearing	0.2	0.7	2.4	0.6	-0.8	1.2	1.2	0.5	-0.6	-0.6	-0.3	0.0	-0.1	-1.6
Locomotion in novel chamber	1.1	1.5	3.3	0.9	-1.1	0.3	0.3	1.5	-1.2	-1.5	-1.3	-1.8	1.8	0.8
Locomotion in novel chamber post-restriction	1.0	3.0	3.9	2.0	-1.7	1.5	1.5	1.9	-1.9	-1.8	-1.9	-1.8	1.9	0.1
Fecal boli incidents, locomotor time 1	0.5	1.2	2.4	1.0	-1.0	0.4	0.4	1.2	-1.1	-1.2	-1.2	-1.5	1.5	0.8
Change in fecal boli incidents, locomotor task	0.7	0.8	1.3	-0.5	1.1	-0.7	-0.7	-1.0	1.0	1.1	1.0	0.9	-1.0	-0.0
Time >=10cm from walls, locomotor time 1	2.0	2.5	3.2	1.5	-1.8	1.3	1.3	1.8	-1.8	-1.7	-1.8	-1.7	1.8	0.3
Bouts of movement, locomotor time 1	0.2	0.3	0.4	0.6	-0.6	0.4	0.4	0.6	-0.6	-0.5	-0.6	-0.4	0.6	-0.0
Total resting periods, locomotor time 1	0.2	0.3	0.7	0.6	-0.4	0.1	0.1	0.6	-0.5	-0.4	-0.7	-0.6	0.8	0.6
Rest time, locomotor task time 1	0.1	0.2	1.0	0.1	0.1	-0.4	-0.4	0.0	-0.1	0.0	-0.3	-0.4	0.5	1.0
Distance moved, locomotor task time 1	0.1	0.3	1.6	-0.3	-0.1	0.5	0.5	-0.0	0.1	0.1	0.3	0.7	-0.7	-1.3
Vertical activity count, locomotor time 1	0.0	0.3	1.1	0.2	-0.5	0.8	0.8	0.2	-0.3	-0.3	-0.1	0.2	-0.4	-1.1
Time >=10cm from walls, locomotor time 2	0.6	1.7	2.6	1.3	-1.5	1.6	1.6	1.3	-1.3	-1.5	-1.2	-1.1	0.8	-0.8
Bouts of movement, locomotor time 2	0.2	0.5	2.1	0.9	-0.4	1.0	1.0	0.3	-0.3	-0.4	-0.1	0.2	-0.3	-1.5
Total resting periods, locomotor time 2	0.1	0.3	1.5	0.5	-0.1	0.6	0.6	-0.0	0.1	-0.1	0.2	0.4	-0.5	-1.2
Rest time, locomotor task time 2	2.0	3.3	4.5	-1.9	2.0	-2.0	-2.0	-2.1	2.0	1.9	1.8	1.5	-1.5	1.0
Distance moved, locomotor task time 2	2.3	3.1	4.6	1.5	-2.1	2.1	2.1	2.0	-1.9	-1.9	-1.7	-1.2	1.2	-1.4
Vertical activity count, locomotor time 2	0.5	1.1	2.1	0.9	-1.3	1.4	1.4	1.0	-1.0	-1.1	-0.8	-0.4	0.3	-1.3
Light reinforcement 1	0.9	4.3	6.5	-2.6	2.1	-2.2	-2.2	-2.3	2.2	2.0	2.2	1.8	-1.9	0.6
Light reinforcement 2	0.1	0.3	0.9	-0.8	0.3	-0.9	-0.9	-0.4	0.4	0.2	0.3	-0.2	-0.0	0.9
Bone: marrow area	0.8	1.9	6.1	1.4	-1.2	2.0	2.1	1.0	-1.0	-0.8	-0.7	0.2	-0.1	-2.5
Bone: maximum diameter	1.2	2.3	4.4	1.7	-1.6	2.0	2.1	1.4	-1.4	-1.4	-1.2	-0.6	0.5	-1.8
Bone: maximum force	0.0	0.0	0.1	-0.3	0.1	-0.2	-0.2	-0.2	0.2	0.0	0.2	-0.0	-0.1	0.1
Bone: maximum moment	0.0	0.0	0.0	-0.0	-0.1	0.0	0.0	-0.0	-0.0	-0.2	0.0	-0.1	-0.0	-0.0
Mean time between licks in bursts	0.7	4.1	8.7	2.1	-2.1	2.9	2.9	1.6	-1.8	-1.6	-1.3	-0.3	0.2	-2.9
Mean num. licks in bursts	2.0	5.3	6.8	2.5	-2.6	2.2	2.2	2.5	-2.5	-2.5	-2.5	-2.3	2.2	-0.3
Cd content in liver	0.6	0.7	1.2	-0.8	0.8	-0.4	-0.4	-0.9	0.8	0.9	0.9	1.1	-1.1	-0.8
Co content in liver	1.0	1.1	2.2	1.1	-1.1	1.5	1.5	0.9	-1.0	-0.9	-0.8	-0.3	0.2	-1.5
Cu content in liver	0.6	0.7	4.0	0.3	-0.3	1.0	1.0	-0.0	-0.1	-0.0	0.2	0.8	-0.8	-2.0
Fe content in liver	0.0	0.1	0.1	-0.3	0.2	-0.3	-0.3	-0.3	0.2	0.2	0.2	0.2	-0.2	-0.0
K content in liver	0.3	0.3	0.6	-0.4	0.4	-0.1	-0.1	-0.6	0.5	0.4	0.6	0.7	-0.8	-0.6
Mg content in liver	0.1	0.1	0.2	0.4	-0.3	0.4	0.4	0.3	-0.3	-0.3	-0.3	-0.2	0.1	-0.4
Mn content in liver	0.8	0.9	2.5	-0.9	1.0	-1.4	-1.4	-0.6	0.8	0.7	0.5	-0.1	0.0	1.6
Na content in liver	0.5	0.6	0.7	0.9	-0.8	0.8	0.8	0.8	-0.8	-0.8	-0.8	-0.7	0.6	-0.0
Rb content in liver	0.3	0.4	0.5	0.7	-0.7	0.7	0.7	0.6	-0.6	-0.6	-0.6	-0.4	0.4	-0.3
Se content in liver	4.3	5.1	8.0	-2.6	2.6	-2.8	-2.8	-2.3	2.3	2.3	2.1	1.4	-1.4	1.6
Sr content in liver	0.2	0.2	0.4	0.4	-0.4	0.1	0.1	0.5	-0.4	-0.5	-0.5	-0.6	0.6	0.6
Zn content in liver	2.4	2.8	4.7	1.9	-1.9	2.2	2.2	1.6	-1.7	-1.6	-1.4	-0.8	0.8	-1.6
Bone: minimum diameter	0.6	1.1	6.2	0.5	-0.3	1.2	1.3	0.0	-0.1	0.1	0.3	1.0	-1.0	-2.5
Time in familiar zone, hab. session 1	0.1	0.1	0.4	-0.1	0.2	0.2	0.2	-0.2	0.2	0.3	0.3	0.5	-0.5	-0.6
Time in novel zone, hab. session 1	0.2	0.2	0.4	-0.6	0.5	-0.6	-0.6	-0.5	0.5	0.5	0.5	0.4	-0.4	0.2
Total zone transitions, hab. session 1	0.2	0.3	1.0	0.2	-0.2	-0.2	-0.3	0.3	-0.3	-0.5	-0.4	-0.9	0.7	1.0
Total locomotion distance, hab. session 1	1.1	1.6	3.2	-1.1	1.2	-0.4	-0.4	-1.4	1.3	1.3	1.5	1.7	-1.8	-1.3
Locomotion velocity, hab. session 1	0.6	0.9	1.8	-0.8	0.8	-0.2	-0.3	-1.0	0.9	0.9	1.1	1.2	-1.3	-1.1
Time in familiar zone, hab. session 2	1.4	1.6	2.6	1.5	-1.4	1.6	1.6	1.2	-1.3	-1.2	-1.2	-0.8	0.7	-1.0
Time in novel zone, hab. session 2	0.4	0.4	0.9	-0.7	0.6	-1.0	-0.9	-0.5	0.6	0.5	0.4	0.1	-0.1	0.8
Total zone transitions, hab. session 2	1.7	2.1	3.0	1.5	-1.6	1.0	1.0	1.6	-1.6	-1.6	-1.7	-1.7	1.7	0.6
Total locomotion distance, hab. session 2	0.4	0.5	2.6	-0.2	0.2	0.5	0.5	-0.4	0.3	0.4	0.6	1.0	-1.0	-1.6
Locomotion velocity, hab. session 2	0.6	0.8	3.1	-0.3	0.4	0.4	0.4	-0.7	0.5	0.7	0.8	1.3	-1.3	-1.8
Novel to familiar place preference ratio	0.0	0.1	0.1	0.2	-0.3	0.3	0.2	0.3	-0.3	-0.2	-0.3	-0.2	0.3	0.1
Novelty place preference	0.0	0.1	0.1	0.2	-0.3	0.3	0.2	0.3	-0.3	-0.2	-0.3	-0.2	0.3	0.1
Time in novel zone, NPP test	0.2	0.2	0.3	0.5	-0.5	0.5	0.4	0.5	-0.5	-0.4	-0.5	-0.4	0.5	0.1
Total zone transitions, NPP test	0.3	0.4	0.9	0.6	-0.6	0.0	0.1	0.7	-0.6	-0.7	-0.7	-0.9	0.9	0.6
Total locomotion distance, NPP test	0.7	1.0	2.0	-0.8	0.9	-0.3	-0.2	-1.0	0.9	1.1	1.1	1.4	-1.4	-1.2
Locomotion velocity, NPP test	1.1	1.6	2.8	-1.1	1.3	-0.6	-0.5	-1.3	1.3	1.4	1.4	1.7	-1.6	-1.1
Intraocular pressure	0.3	0.5	1.3	0.5	-0.5	0.0	0.1	0.7	-0.6	-0.8	-0.7	-1.1	1.1	0.8
Delta distance traveled before/after self-admin	2.0	2.2	3.7	1.7	-1.2	1.0	1.0	1.6	-1.6	-1.3	-1.8	-1.7	1.9	0.8
Delta ambulatory time before/after self-admin	1.2	2.1	3.8	1.7	-1.2	1.0	0.9	1.6	-1.6	-1.3	-1.8	-1.7	1.9	0.9
Parametrial fat weight	0.8	1.8	2.6	-1.5	1.4	-0.9	-1.0	-1.6	1.4	1.5	1.5	1.5	-1.6	-0.2
Pavlov. Cond. lever latency	1.5	1.9	2.6	-1.6	1.6	-1.5	-1.6	-1.5	1.5	1.5	1.3	1.0	-1.0	0.8
Pavlov. Cond. magazine entry latency	3.2	4.2	5.8	2.3	-2.4	2.4	2.4	2.1	-2.2	-2.1	-2.0	-1.4	1.4	-1.3
Pavlov. Cond. change in total contacts	1.4	1.5	2.1	1.4	-1.4	1.5	1.4	1.3	-1.3	-1.3	-1.2	-0.9	0.8	-0.8
Pavlov. Cond. index score	2.8	3.6	5.1	2.1	-2.2	2.2	2.3	2.0	-2.0	-2.0	-1.8	-1.3	1.3	-1.2
Pavlov. Cond. latency score	2.7	3.5	4.8	2.1	-2.2	2.1	2.2	1.9	-2.0	-2.0	-1.8	-1.3	1.3	-1.2
Pavlov. Cond. lever contacts	1.3	1.6	2.4	1.5	-1.5	1.4	1.5	1.3	-1.3	-1.3	-1.2	-0.9	0.8	-0.9
Pavlov. Cond. magazine entry number	3.4	4.3	5.9	-2.3	2.4	-2.4	-2.4	-2.2	2.2	2.2	2.0	1.5	-1.5	1.2
Pavlov. Cond. intertrial magazine entries	0.9	1.1	1.7	-1.2	1.2	-1.3	-1.3	-1.1	1.1	1.1	1.0	0.7	-0.7	0.8
Pavlov. Cond. lever-magazine prob. diff.	2.3	2.8	4.0	1.9	-2.0	2.0	2.0	1.8	-1.8	-1.7	-1.6	-1.1	1.1	-1.1
Pavlov. Cond. response bias	1.5	1.9	2.7	1.6	-1.6	1.6	1.7	1.4	-1.5	-1.5	-1.3	-1.0	0.9	-0.9
Pavlov. Cond. lever latency	18.1	25.4	33.6	-5.8	5.7	-5.7	-5.7	-5.4	5.4	5.3	5.0	4.0	-3.9	2.5
Pavlov. Cond. magazine entry latency	4.0	5.7	7.3	2.7	-2.7	2.4	2.4	2.6	-2.6	-2.6	-2.5	-2.3	2.2	-0.4
Pavlov. Cond. change in total contacts	7.9	19.3	25.2	5.0	-5.0	4.9	4.9	4.7	-4.7	-4.7	-4.4	-3.5	3.5	-2.0
Pavlov. Cond. index score	11.9	18.7	24.7	5.0	-4.9	4.9	4.8	4.6	-4.6	-4.6	-4.3	-3.5	3.4	-2.0
Pavlov. Cond. latency score	10.3	16.5	21.9	4.7	-4.6	4.5	4.5	4.3	-4.3	-4.3	-4.1	-3.4	3.2	-1.8
Pavlov. Cond. lever contacts	16.3	24.0	31.5	5.6	-5.6	5.6	5.6	5.2	-5.2	-5.2	-4.8	-3.8	3.7	-2.5
Pavlov. Cond. magazine entry number	7.7	10.0	12.6	-3.5	3.6	-3.2	-3.2	-3.4	3.4	3.4	3.3	2.9	-2.9	0.6
Pavlov. Cond. intertrial magazine entries	0.3	0.6	2.7	-0.1	0.1	0.6	0.6	-0.3	0.3	0.4	0.5	1.1	-1.1	-1.6
Pavlov. Cond. lever-magazine prob. diff.	11.2	17.2	22.7	4.8	-4.7	4.8	4.7	4.4	-4.4	-4.4	-4.1	-3.3	3.2	-2.0
Pavlov. Cond. response bias	18.0	24.9	32.5	5.7	-5.7	5.6	5.6	5.3	-5.3	-5.3	-5.0	-4.0	3.9	-2.3
Time in closed arm before self-admin	1.8	3.1	5.9	1.6	-1.6	0.8	0.9	2.0	-1.9	-1.8	-2.1	-2.3	2.4	1.1
Time in closed arm after self-admin	0.6	0.7	1.9	-0.6	1.0	-1.4	-1.1	-0.6	0.7	0.7	0.5	-0.1	-0.1	1.1
Time in open arm before self-admin	3.2	3.9	5.7	-2.4	2.0	-1.8	-2.1	-2.2	2.2	1.9	2.2	1.9	-1.9	0.3
Time in open arm after self-admin	0.2	0.3	1.1	-0.1	-0.3	0.8	0.5	-0.1	0.0	-0.1	0.2	0.6	-0.6	-1.1
Bone: periosteal estimation	0.7	1.6	4.5	1.3	-1.2	1.8	1.9	1.0	-1.0	-0.9	-0.7	-0.0	-0.0	-2.1
Bone: periosteal perimeter	0.8	1.5	3.7	1.3	-1.2	1.8	1.8	1.0	-1.0	-1.0	-0.8	-0.2	0.1	-1.9
Bone: post-yield work	0.0	0.0	0.1	0.2	-0.2	0.3	0.3	0.2	-0.2	-0.1	-0.1	0.0	0.0	-0.3
Progressive ratio test 1 active lever presses	0.0	0.1	0.5	0.3	0.2	-0.2	-0.1	-0.0	-0.1	0.1	-0.3	-0.3	0.2	0.7
Progressive ratio test 1 breakpoint	0.0	0.1	0.4	0.3	0.2	-0.2	-0.1	-0.0	-0.1	0.2	-0.2	-0.3	0.2	0.6
Progressive ratio test 1 inactive lever presses	0.0	0.1	0.3	-0.1	0.3	-0.3	-0.2	-0.4	0.1	0.5	-0.1	0.2	-0.3	0.6
Progressive ratio test 2 active lever presses	0.3	0.5	0.8	0.7	-0.8	0.9	0.9	0.7	-0.8	-0.7	-0.7	-0.5	0.4	-0.3
Progressive ratio test 2 breakpoint	0.4	0.5	0.8	0.8	-0.8	0.9	0.9	0.7	-0.8	-0.7	-0.7	-0.6	0.4	-0.3
Progressive ratio test 2 inactive lever presses	0.1	0.4	0.6	0.4	-0.7	0.4	0.5	0.6	-0.7	-0.6	-0.8	-0.7	0.6	0.5
Incentive Sensitization - Responses	0.3	0.9	1.7	0.7	-1.3	1.3	1.1	1.0	-1.0	-1.2	-0.8	-0.7	0.6	-0.6
Incentive Sensitization - Breakpoint	0.4	0.9	1.6	0.7	-1.3	1.2	1.0	1.0	-1.0	-1.2	-0.8	-0.8	0.7	-0.5
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.4	-0.5	-0.4	-0.4	-0.4	0.2	-0.1	-0.5	-0.2	-0.5	0.4	0.6
Progressive ratio	0.2	0.6	1.2	0.5	-0.9	0.3	0.5	0.9	-0.8	-1.0	-0.9	-1.1	0.9	0.5
Food seeking constrained by brief footshock	1.0	1.2	2.3	1.1	-1.3	1.4	1.5	1.1	-1.0	-1.2	-0.8	-0.4	0.3	-1.5
Seeking ratio, punishment vs. effort	0.3	0.7	4.1	0.6	-0.3	1.1	1.0	0.0	-0.1	0.1	0.1	0.9	-0.7	-2.0
Retroperitoneal fat weight	2.7	12.1	22.3	-3.3	3.3	-1.6	-1.6	-3.8	3.5	3.8	3.9	4.7	-4.6	-2.5
Reaction time number correct	0.2	0.9	2.3	0.2	-0.6	-0.3	-0.4	0.8	-0.6	-0.9	-0.8	-1.4	1.4	1.5
Reaction time mean minus median	0.1	0.8	1.5	0.9	-1.1	1.2	1.1	0.8	-0.9	-0.9	-0.7	-0.3	0.4	-0.8
Reaction time mean minus median AUC	0.2	1.5	2.2	1.3	-1.5	1.3	1.2	1.2	-1.3	-1.3	-1.3	-1.0	1.1	-0.2
Reaction time num false alarms	1.8	3.1	3.8	-1.9	1.9	-1.6	-1.6	-1.8	1.9	1.9	1.9	1.9	-1.8	-0.2
Reaction time num false alarms AUC	0.7	1.5	1.9	-1.4	1.3	-1.3	-1.1	-1.3	1.3	1.3	1.3	1.3	-1.2	-0.0
Reaction time trials correct on left	0.2	0.9	2.3	0.2	-0.6	-0.3	-0.4	0.8	-0.6	-0.9	-0.8	-1.4	1.4	1.5
Reaction time trials on left	0.3	0.9	2.4	0.2	-0.6	-0.4	-0.5	0.8	-0.6	-0.9	-0.8	-1.4	1.5	1.5
Reaction time mean	0.7	1.5	2.4	-1.4	1.2	-0.8	-0.9	-1.3	1.2	1.4	1.3	1.6	-1.4	-0.2
Reaction time mean AUC	0.8	1.8	2.5	-1.5	1.4	-1.0	-1.2	-1.5	1.4	1.6	1.4	1.6	-1.4	0.2
Median of all reaction times	1.6	2.5	3.4	-1.9	1.7	-1.3	-1.4	-1.7	1.6	1.8	1.7	1.8	-1.6	0.2
Reaction time omissions	0.2	0.3	0.7	-0.6	0.3	-0.2	-0.1	-0.6	0.5	0.5	0.6	0.8	-0.8	-0.6
Reaction time false alarm rate	1.8	2.4	3.8	-1.5	1.7	-1.1	-1.0	-1.7	1.6	1.8	1.7	1.9	-1.9	-0.7
Reaction time premature initiation rate	1.0	1.5	6.2	1.1	-0.9	1.7	1.9	0.6	-0.7	-0.6	-0.3	0.5	-0.6	-2.5
Reaction time premature initiations	0.4	1.3	2.3	1.3	-1.3	1.4	1.5	1.1	-1.1	-1.1	-0.9	-0.5	0.4	-1.3
Std. dev. reaction times	0.1	0.4	2.2	0.2	-0.2	0.8	0.7	-0.1	-0.0	0.1	0.3	0.8	-0.7	-1.5
Reaction time trials completed	0.3	0.9	2.4	0.2	-0.6	-0.4	-0.5	0.8	-0.6	-0.9	-0.8	-1.4	1.5	1.5
Reaction time trials AUC	0.2	0.7	1.7	0.2	-0.6	-0.3	-0.4	0.8	-0.5	-0.8	-0.7	-1.3	1.3	1.3
Run reversals in cocaine runway, females	2.1	2.3	5.6	-0.9	1.0	0.2	0.2	-1.4	1.2	1.5	1.5	2.4	-2.3	-2.1
Run reversals in cocaine runway, males	0.1	0.1	0.2	-0.2	0.3	-0.4	-0.2	-0.3	0.2	0.4	0.2	0.3	-0.2	0.3
Latency to leave start box in cocaine runway	3.7	5.1	7.2	-2.3	2.4	-1.5	-1.7	-2.6	2.5	2.5	2.6	2.5	-2.7	-0.4
Latency to leave start box in cocaine runway, F	4.4	5.5	9.3	-2.2	2.4	-1.2	-1.4	-2.7	2.5	2.5	2.7	2.9	-3.0	-1.1
Latency to leave start box in cocaine runway, M	0.3	0.3	0.6	-0.6	0.7	-0.7	-0.8	-0.6	0.6	0.5	0.5	0.2	-0.2	0.7
Std. dev. time between licks in bursts	0.7	1.3	5.9	0.8	-0.8	1.6	1.6	0.4	-0.5	-0.4	-0.1	0.6	-0.6	-2.4
Total sessions with >9 infusions	2.5	3.1	5.9	2.4	-1.8	2.2	2.3	1.6	-1.9	-1.6	-1.8	-1.2	1.0	-0.8
Short access day 1 total inactive lever presses	0.0	0.1	0.2	0.3	0.1	0.4	0.2	-0.4	0.0	0.3	-0.1	0.3	-0.4	-0.0
Short access day 10 total inactive lever presses	0.1	0.7	1.3	-1.1	1.1	-1.1	-1.1	-0.8	0.9	0.9	0.8	0.4	-0.4	0.6
Short access day 1 total infusions	2.1	4.2	7.4	2.7	-2.3	2.7	2.7	1.9	-2.2	-1.8	-2.0	-1.1	1.0	-1.3
Short access day 10 total infusions	1.4	2.3	3.7	1.9	-1.6	1.8	1.9	1.6	-1.6	-1.4	-1.5	-1.0	0.9	-0.8
Short access total infusions	2.2	3.1	4.9	2.2	-1.9	2.2	2.2	1.7	-1.9	-1.6	-1.9	-1.2	1.1	-0.6
Short access day 1 locomotion	1.9	3.2	4.2	2.0	-2.0	1.6	1.7	1.8	-2.0	-1.8	-2.1	-1.8	1.7	0.2
Short access day 10 total locomotion	0.5	2.0	2.8	1.6	-1.5	1.3	1.4	1.6	-1.5	-1.7	-1.4	-1.5	1.3	-0.6
Short access total locomotion	0.6	0.9	1.4	1.0	-1.0	0.6	0.9	1.1	-1.1	-1.1	-1.1	-1.2	1.0	0.2
One hour access (0.3 mA shock)	1.6	1.8	2.3	1.5	-1.4	1.4	1.4	1.5	-1.4	-1.5	-1.4	-1.4	1.2	-0.2
Compulsive drug intake	0.7	1.0	4.1	-1.1	0.4	-1.4	-1.6	-0.3	0.4	0.1	0.2	-0.6	0.6	2.0
One hour access (shock baseline)	1.2	3.1	4.8	2.2	-1.8	2.1	2.0	1.8	-1.8	-1.7	-1.8	-1.5	1.4	-0.7
Social response proportion	0.5	0.7	1.1	-0.6	1.0	-0.3	-0.4	-0.9	0.9	0.9	1.0	0.9	-1.1	-0.6
Social responses	0.9	1.1	2.5	-0.7	0.9	0.1	-0.1	-1.1	0.9	1.1	1.1	1.5	-1.6	-1.3
Social time	1.9	2.9	4.1	-1.9	2.0	-2.0	-2.0	-1.9	1.9	1.7	1.6	1.0	-1.1	1.3
Soleus weight	0.8	2.3	6.6	-0.9	0.9	0.1	0.2	-1.3	1.2	1.3	1.6	2.2	-2.2	-2.6
Bone: stiffness	0.5	1.0	1.3	-1.0	1.1	-0.7	-0.7	-1.1	1.1	1.1	1.1	1.1	-1.1	-0.3
Tibialis anterior weight	0.1	0.3	1.9	0.1	-0.1	0.5	0.6	-0.2	0.1	0.1	0.3	0.6	-0.7	-1.4
Time to tail flick, vehicle, before self-admin	0.2	0.3	0.6	0.3	-0.5	0.3	0.3	0.7	-0.5	-0.7	-0.6	-0.8	0.7	0.1
Time to tail flick, vehicle, after self-admin	0.9	1.8	3.4	1.8	-1.5	1.3	1.6	1.2	-1.4	-1.3	-1.5	-1.1	1.0	-0.3
Time to tail flick, test, before self-admin	0.4	0.4	1.7	0.4	-0.5	1.0	1.0	0.4	-0.4	-0.1	-0.2	0.6	-0.3	-1.3
Time to tail flick, test, after self-admin	0.4	0.4	1.9	0.2	-0.2	1.0	0.8	0.0	-0.1	0.1	0.1	0.7	-0.6	-1.4
Delta time to tail flick, vehicle, before/after SA	0.5	0.6	1.4	1.2	-0.9	0.8	1.1	0.5	-0.8	-0.6	-0.8	-0.3	0.3	-0.3
Delta time to tail flick, test, before/after SA	0.3	0.4	0.6	-0.6	0.8	-0.6	-0.7	-0.7	0.7	0.6	0.7	0.4	-0.4	0.4
Tibia length	2.1	5.7	7.7	2.5	-2.6	1.7	1.7	2.7	-2.6	-2.7	-2.7	-2.8	2.8	0.7
Ambulatory time before self-admin	0.3	1.0	2.4	-0.9	1.1	-1.6	-1.2	-1.0	1.1	0.8	1.0	0.5	-0.6	0.7
Ambulatory time after self-admin	0.6	0.9	4.2	0.6	0.1	-0.9	-0.6	0.4	-0.3	-0.2	-0.7	-1.2	1.4	2.0
Bone: tissue strength	0.7	0.7	3.8	-0.5	0.3	-1.2	-1.2	-0.2	0.2	0.1	-0.0	-0.6	0.6	1.9
Total heroin consumption	0.1	0.1	0.2	-0.0	-0.4	0.1	-0.1	0.2	-0.2	-0.4	-0.3	-0.4	0.3	0.4
Bone: trabecular number	0.8	1.5	3.0	-1.3	1.3	-1.7	-1.7	-1.0	1.2	1.1	1.0	0.4	-0.3	1.5
Bone: trabecular spacing	0.8	1.2	1.7	1.2	-1.3	1.1	1.1	1.2	-1.2	-1.2	-1.2	-1.0	1.0	-0.2
Bone: trabecular thickness	0.5	0.7	0.9	-1.0	0.9	-0.9	-0.8	-0.9	0.9	0.8	1.0	0.8	-0.8	0.1
Bone: trabecular tissue density	1.7	3.0	4.4	-1.8	1.8	-1.1	-1.1	-1.9	1.9	1.9	2.0	2.1	-2.1	-0.9
Water consumed over 24 hours	0.2	0.4	0.7	-0.7	0.7	-0.8	-0.8	-0.7	0.7	0.6	0.6	0.4	-0.4	0.5
Number of responses in last shaping day	0.5	0.7	1.6	-0.6	0.8	-0.3	-0.1	-0.8	0.8	0.9	0.9	1.2	-1.3	-0.9