Emsy

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Emsy 0.06 0.04 1.2e-04 0.02 0.05 0.05 0.04 3.9e-03 4.0e-05 2.9e-05 7.3e-05
2 Brain alternative TSS NM_001400843.1 0.03 0.02 6.3e-03 0.01 0.01 0.01 0.01 4.3e-02 2.2e-02 1.3e-02 3.6e-02
3 Eye intron excision ratio chr1_152939231_152942631 0.54 0.3 5.1e-03 0.1 0.08 0.08 0.1 1.2e-02 2.3e-02 2.3e-02 1.3e-02
4 Brain alternative TSS XM_006229802.4 0.03 0.02 4.4e-03 0.01 0.01 0.02 0.01 4.0e-02 1.9e-02 1.2e-02 2.7e-02
5 Brain alternative TSS XM_006229811.4 0.03 0.02 7.3e-03 0.01 0.01 0.01 0.01 7.3e-02 4.5e-02 2.7e-02 7.1e-02
6 RMTg intron excision ratio chr1_152888906_152889670 0.15 0.1 5.2e-03 0.08 0.03 0.04 0.06 3.9e-03 4.6e-02 3.2e-02 1.3e-02
7 PL gene expression Emsy 0.04 0.03 8.0e-04 0.03 0.03 0.03 0.03 2.4e-04 3.4e-04 2.7e-04 6.8e-04
8 Adipose alternative polyA XM_006229811.4 0.03 0.02 2.1e-03 0.01 0.01 0 0.01 3.4e-02 8.0e-03 7.9e-02 2.5e-02
9 Brain intron excision ratio chr1_152935575_152939056 0.04 0.03 1.3e-03 0.03 0.03 0.03 0.02 1.7e-03 8.4e-04 2.2e-03 2.7e-03
10 Adipose alternative polyA XM_006229802.4 0.06 0.04 1.4e-05 0.01 0.03 0.03 0.03 1.3e-02 1.0e-04 1.7e-04 3.2e-04
11 Adipose gene expression Emsy 0.49 0.12 0.0e+00 0.36 0.35 0.36 0.36 3.3e-41 1.0e-40 3.7e-41 1.1e-41
12 Adipose isoform ratio NM_001400843.1 0.38 0.13 0.0e+00 0.26 0.28 0.28 0.27 5.3e-29 8.5e-32 7.5e-32 4.4e-30
13 Adipose mRNA stability Emsy 0.15 0.09 4.8e-11 0.08 0.07 0.08 0.07 1.8e-09 2.9e-08 7.6e-09 1.1e-08
14 Adipose isoform ratio XM_006229812.4 0.19 0.09 0.0e+00 0.13 0.14 0.14 0.14 1.1e-14 1.6e-15 1.2e-15 1.6e-15
15 Adipose intron excision ratio chr1_152951834_152953428 0.1 0.06 3.7e-10 0.07 0.06 0.06 0.06 4.3e-08 2.8e-07 5.3e-07 9.4e-08
16 Adipose alternative TSS NM_001400843.1 0.46 0.13 0.0e+00 0.27 0.3 0.3 0.29 4.8e-30 3.5e-34 6.0e-34 1.7e-32
17 Adipose alternative TSS NM_001400843.1 0.47 0.14 0.0e+00 0.27 0.3 0.3 0.29 7.3e-30 3.6e-34 7.3e-34 1.8e-32
18 Adipose alternative TSS XM_006229802.4 0.48 0.13 0.0e+00 0.27 0.31 0.31 0.3 2.8e-30 1.0e-34 1.6e-34 5.1e-33
19 Adipose alternative TSS XM_006229811.4 0.49 0.14 0.0e+00 0.27 0.31 0.31 0.3 2.6e-30 8.8e-35 1.5e-34 3.2e-33

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.10.20.6-0.7-0.5-0.80.50.4-0.3-0.20.4-0.20.4-0.00.0-0.50.3-0.60.40.4-0.3-0.4
Area under the delay curve0.10.10.20.10.20.2-0.2-0.30.20.1-0.30.3-0.30.40.3-0.2-0.40.2-0.3-0.30.30.3
BMI with tail0.31.13.6-0.4-0.7-0.10.61.0-0.4-1.31.3-1.21.3-1.1-1.01.91.2-1.40.80.9-0.9-0.9
BMI without tail4.38.916.2-0.4-1.31.01.31.6-1.8-2.63.3-3.73.5-3.5-3.53.83.6-4.03.53.5-3.5-3.5
Body weight1.66.613.7-0.3-1.01.11.11.4-1.5-2.02.9-3.33.1-3.1-3.03.73.2-3.12.92.9-2.9-2.9
Weight adjusted by age1.61.83.60.5-0.11.20.00.2-0.6-0.61.2-1.81.4-1.7-1.81.91.6-1.71.51.5-1.5-1.6
Bone surface0.50.92.01.00.91.2-0.8-0.90.60.90.2-1.30.4-1.1-1.10.61.0-1.41.11.1-1.1-1.0
Bone volume0.50.92.40.50.30.8-0.3-0.30.00.20.6-1.40.8-1.1-1.20.71.2-1.51.31.3-1.3-1.3
Breakpoint value in progressive ratio session0.20.30.5-0.4-0.2-0.60.20.20.1-0.1-0.30.7-0.40.70.7-0.6-0.60.7-0.6-0.60.60.6
Number of licking bursts1.92.26.4-2.5-2.4-2.32.42.4-1.9-2.21.50.31.30.10.3-0.20.30.30.10.1-0.1-0.1
Context. condit. distance diff. score1.11.43.71.91.80.8-1.9-1.81.81.5-1.4-0.2-1.20.20.4-0.3-0.8-0.1-0.7-0.70.70.7
Locomotion velocity, session 10.91.02.4-0.00.3-0.2-0.2-0.40.20.2-0.91.5-1.11.51.2-1.1-1.31.5-1.1-1.21.11.2
Locomotion distance, session 11.11.42.01.21.30.8-1.3-1.31.31.1-1.41.0-1.40.90.8-0.4-1.21.2-1.2-1.31.21.2
Locomotion velocity, session 20.10.10.80.40.40.9-0.3-0.40.1-0.0-0.10.2-0.10.1-0.10.2-0.10.30.20.2-0.2-0.2
Locomotion distance, session 20.20.30.70.80.90.8-0.9-0.90.70.4-0.50.2-0.50.20.10.2-0.40.3-0.2-0.20.20.2
Locomotion velocity, session 30.40.51.21.11.00.6-1.0-0.90.90.4-0.90.4-0.90.60.4-0.1-0.80.3-0.6-0.60.60.6
Locomotion distance, session 31.41.52.71.31.50.5-1.5-1.41.71.0-1.50.9-1.41.11.0-0.7-1.30.8-1.2-1.21.21.2
Stereotopy head waving bouts, day 30.40.51.2-0.7-0.9-0.11.00.9-1.1-0.80.8-0.30.7-0.5-0.60.20.7-0.10.60.6-0.6-0.6
Stereotopy head waving duration, day 30.10.20.40.60.60.6-0.6-0.60.50.5-0.50.1-0.40.10.0-0.3-0.30.1-0.0-0.00.00.0
Locomotion velocity, session 70.10.10.5-0.3-0.3-0.70.20.3-0.2-0.6-0.10.3-0.10.30.5-0.2-0.30.3-0.4-0.40.40.4
Locomotion distance, session 70.10.10.4-0.1-0.2-0.20.20.3-0.2-0.60.4-0.40.4-0.2-0.10.50.1-0.30.20.2-0.2-0.2
Stereotopy head waving bouts, day 71.11.22.61.51.51.2-1.5-1.51.51.6-1.40.5-1.30.50.3-0.6-0.80.7-0.7-0.80.70.8
Stereotopy head waving duration, day 71.01.23.21.81.71.7-1.7-1.71.61.6-1.1-0.1-0.9-0.0-0.2-0.1-0.30.0-0.1-0.20.10.2
Locomotion velocity, session 80.60.82.21.21.50.9-1.4-1.51.51.4-0.9-0.1-0.80.10.1-0.5-0.40.1-0.1-0.20.20.2
Locomotion distance, session 80.91.43.71.91.91.3-1.9-1.91.61.4-1.40.1-1.20.20.2-0.0-0.70.3-0.6-0.70.60.6
Degree of sensitization distance2.32.33.7-0.9-1.20.01.31.3-1.4-1.21.9-1.71.9-1.7-1.51.61.7-1.61.81.8-1.8-1.8
Degree of sensitization stereotypy2.73.06.52.32.41.8-2.4-2.42.52.6-2.10.7-1.90.70.5-0.8-1.21.0-1.1-1.21.11.2
Conditioned locomotion0.20.20.50.20.3-0.2-0.3-0.30.40.3-0.50.6-0.60.50.5-0.7-0.60.6-0.5-0.50.50.5
Cocaine response after cond. corrected0.50.61.7-1.3-1.3-0.81.31.3-1.0-1.10.90.10.8-0.1-0.10.30.30.30.00.1-0.1-0.1
Cocaine response after cond. not corrected0.20.20.6-0.6-0.5-0.40.50.5-0.2-0.30.10.5-0.00.40.4-0.1-0.30.8-0.5-0.50.50.5
Cocaine response before conditioning1.11.32.11.21.30.7-1.3-1.41.31.4-1.40.7-1.40.90.8-1.1-1.11.0-1.0-1.11.11.1
Saline control response0.81.14.41.41.02.1-0.9-1.00.21.00.0-1.10.2-1.3-1.31.20.9-0.70.90.9-0.9-0.9
Bone: connectivity density0.10.11.1-0.00.2-0.4-0.2-0.40.30.5-0.30.1-0.30.30.4-1.1-0.2-0.3-0.1-0.10.10.1
Bone: cortical apparent density0.81.12.4-1.5-1.6-0.81.51.5-1.6-1.31.2-0.21.1-0.4-0.40.10.8-0.40.80.8-0.8-0.8
Bone: cortical area0.71.12.90.50.30.7-0.3-0.10.10.10.8-1.61.0-1.4-1.31.41.3-1.71.11.1-1.1-1.1
Bone: cortical porosity1.41.52.61.61.61.1-1.6-1.61.61.4-1.60.8-1.50.80.6-0.7-1.20.9-1.0-1.00.91.0
Bone: cortical porosity1.21.32.11.31.40.9-1.4-1.41.41.2-1.50.9-1.40.90.7-0.7-1.21.0-1.0-1.01.01.0
Bone: cortical thickness0.10.20.4-0.5-0.6-0.70.50.7-0.4-0.40.5-0.30.5-0.1-0.00.30.3-0.50.10.1-0.1-0.1
Bone: cortical thickness0.20.20.50.60.40.3-0.5-0.40.50.5-0.50.2-0.50.20.30.2-0.40.3-0.7-0.70.70.7
Bone: cortical tissue density0.71.02.3-1.5-1.5-0.91.51.4-1.5-1.31.2-0.11.0-0.3-0.30.00.7-0.20.70.7-0.7-0.7
Condit. Reinf. active minus inactive responses1.11.22.5-0.1-0.30.30.30.5-0.2-1.01.2-1.51.3-1.3-1.31.51.3-1.61.31.3-1.3-1.3
Condit. Reinf. active-inactive response ratio1.31.43.20.2-0.10.60.10.2-0.2-0.51.1-1.81.3-1.6-1.41.41.5-1.81.41.4-1.4-1.4
Condit. Reinf. active responses0.50.61.2-0.3-0.50.00.50.6-0.2-1.10.9-0.91.0-0.8-0.81.00.9-1.00.80.9-0.8-0.9
Condit. Reinf. inactive responses0.10.10.3-0.2-0.2-0.20.20.20.1-0.6-0.00.4-0.10.40.20.0-0.30.3-0.2-0.20.20.2
Incentive salience index mean0.70.91.70.0-0.20.30.20.4-0.1-1.01.0-1.21.1-1.1-1.11.31.1-1.31.11.1-1.1-1.1
Condit. Reinf. lever presses0.10.10.30.0-0.10.20.10.1-0.1-0.50.3-0.30.3-0.2-0.40.30.4-0.20.40.4-0.4-0.4
Condit. Reinf. active minus inactive responses2.73.39.42.92.53.1-2.5-2.32.11.9-0.5-1.8-0.1-1.8-1.72.11.0-1.40.80.8-0.8-0.8
Condit. Reinf. active-inactive response ratio0.50.51.71.31.11.0-1.1-1.01.00.5-0.5-0.5-0.3-0.5-0.41.00.1-0.2-0.1-0.10.10.1
Condit. Reinf. active responses4.15.616.53.32.84.1-2.8-2.62.32.2-0.2-2.60.4-2.6-2.52.81.9-2.11.61.6-1.6-1.6
Condit. Reinf. inactive responses3.23.911.62.21.83.4-1.7-1.71.31.60.3-2.20.7-2.3-2.52.11.9-2.02.01.9-2.0-1.9
Condit. Reinf. lever presses7.610.330.35.35.05.5-4.9-4.94.34.6-2.2-1.9-1.5-1.9-1.91.50.7-1.40.70.6-0.7-0.6
Condit. Reinf. lever reinforcers received4.36.018.13.63.24.3-3.1-2.92.72.5-0.5-2.50.1-2.5-2.42.71.6-2.01.41.4-1.4-1.4
Conditioned reinforcement - actives2.02.03.91.82.01.1-1.9-2.02.01.9-1.80.7-1.60.70.7-0.7-1.20.9-1.0-1.11.01.1
Conditioned reinforcement - inactives0.10.20.5-0.7-0.5-0.50.50.4-0.3-0.00.10.50.00.40.4-0.5-0.50.7-0.1-0.10.10.1
Conditioned locomotion1.82.24.21.82.01.2-2.0-2.02.02.0-1.90.9-1.70.90.9-0.6-1.40.8-1.1-1.11.11.1
Patch foraging indifference point 0 sec2.13.49.93.22.93.0-2.9-2.82.32.6-1.3-1.3-0.9-1.2-1.00.90.3-0.80.40.4-0.4-0.3
Patch foraging indifference point AUC0.30.40.8-0.1-0.30.30.30.3-0.3-0.20.6-0.80.7-0.9-0.90.60.8-0.70.80.8-0.8-0.8
Delay disc. indifference point, 0s delay0.30.31.10.90.81.1-0.8-0.70.70.5-0.3-0.3-0.1-0.3-0.40.60.1-0.30.10.1-0.1-0.1
Delay disc. indifference point, 16s delay0.40.40.7-0.10.2-0.3-0.2-0.30.40.1-0.60.8-0.60.90.8-0.9-0.80.7-0.7-0.70.70.8
Delay disc. indifference point, 2s delay0.60.61.71.31.31.2-1.3-1.31.11.1-0.8-0.0-0.70.0-0.00.2-0.40.1-0.3-0.30.30.3
Delay disc. indifference point, 24s delay0.50.51.5-1.2-1.1-1.01.21.1-1.1-0.90.60.30.40.20.1-0.40.20.4-0.0-0.00.00.0
Delay disc. indifference point, 4s delay0.30.31.70.80.61.3-0.5-0.50.30.10.1-0.40.2-0.4-0.61.00.4-0.30.40.3-0.4-0.3
Delay disc. indifference point, 8s delay0.20.20.50.50.60.3-0.6-0.60.70.6-0.50.1-0.50.30.2-0.3-0.50.0-0.3-0.30.30.3
Indifference point function ln k1.52.03.61.71.91.0-1.9-1.91.81.8-1.80.8-1.71.01.0-0.7-1.30.8-1.2-1.21.21.2
Indifference point function log k1.52.03.61.71.91.0-1.9-1.91.81.8-1.80.8-1.71.01.0-0.7-1.30.8-1.2-1.21.21.2
Patch foraging total patch changes 0 sec1.72.88.02.82.62.7-2.6-2.62.12.4-1.2-1.1-0.9-1.0-0.90.70.2-0.60.30.2-0.3-0.2
Patch foraging total patch changes 12 sec1.11.43.01.00.71.4-0.7-0.60.30.40.5-1.70.7-1.7-1.61.31.3-1.41.31.3-1.3-1.3
Patch foraging total patch changes 18 sec1.31.73.61.51.01.9-1.0-0.90.20.60.3-1.60.6-1.7-1.71.31.3-1.71.41.4-1.4-1.4
Patch foraging total patch changes 24 sec0.50.61.50.90.71.2-0.7-0.60.40.20.2-0.80.3-1.0-0.91.10.6-0.80.70.7-0.7-0.7
Patch foraging total patch changes 6 sec0.50.72.31.31.40.9-1.4-1.31.41.5-0.9-0.4-0.7-0.3-0.1-0.0-0.2-0.2-0.1-0.20.20.2
Patch foraging time to switch 0 sec1.72.67.9-2.5-2.3-2.82.22.2-1.8-1.80.61.50.31.41.4-1.3-0.81.1-0.9-0.80.90.8
Patch foraging water rate 0 sec1.42.36.62.62.52.5-2.4-2.42.11.9-1.1-0.8-0.8-0.8-0.80.80.2-0.50.30.2-0.3-0.2
Patch foraging water rate 12 sec1.11.64.72.22.12.0-2.1-2.11.91.5-1.2-0.2-1.0-0.1-0.20.2-0.4-0.20.00.0-0.0-0.0
Patch foraging water rate 18 sec0.30.51.41.01.01.2-0.9-0.90.80.4-0.1-0.60.0-0.6-0.60.70.3-0.30.50.5-0.5-0.5
Patch foraging water rate 24 sec1.11.53.41.51.70.8-1.7-1.71.81.2-1.60.7-1.50.90.7-0.7-1.20.7-0.9-0.90.80.8
Patch foraging water rate 6 sec0.60.91.91.21.40.7-1.4-1.41.41.3-1.10.3-1.00.50.4-0.6-0.70.5-0.5-0.60.60.6
Seeking ratio, delayed vs. immediate footshock0.70.92.5-1.6-1.4-1.51.41.4-1.2-1.40.60.70.40.50.5-0.4-0.10.4-0.2-0.20.20.2
Distance traveled before self-admin0.20.21.0-0.8-0.8-0.70.90.8-1.0-0.40.40.10.30.10.1-0.20.10.1-0.00.00.00.0
Distance traveled after self-admin1.11.22.3-0.9-0.7-1.30.70.6-0.5-0.2-0.51.5-0.71.41.4-1.3-1.11.5-1.2-1.21.21.2
Extensor digitorum longus weight0.72.74.2-0.9-1.3-0.21.31.3-1.8-1.42.0-1.92.0-1.7-1.61.62.0-2.01.71.7-1.7-1.7
Bone: elastic displacement0.70.82.8-1.4-1.1-1.71.11.1-0.7-0.90.20.80.00.81.0-0.9-0.70.3-0.6-0.60.60.6
Bone: elastic work1.21.54.1-1.5-1.1-2.01.10.9-0.8-0.6-0.21.4-0.51.51.6-1.8-1.11.0-1.2-1.21.21.2
Bone: endosteal estimation1.22.64.91.00.61.9-0.6-0.50.10.21.0-2.21.3-2.1-2.21.91.9-2.01.91.9-1.9-1.9
Bone: endosteal perimeter1.22.55.31.61.42.3-1.3-1.30.80.90.5-2.00.8-1.9-2.01.81.7-1.71.71.7-1.7-1.7
Epididymis fat weight2.14.87.6-1.2-1.8-0.11.82.0-2.1-2.42.7-2.22.7-2.2-2.12.82.5-2.62.22.2-2.2-2.3
Delta time in closed arm before/after self-admin2.42.33.5-1.1-1.4-0.21.51.5-1.8-1.51.9-1.51.9-1.4-1.41.11.8-1.51.61.6-1.6-1.6
Delta time in open arm before/after self-admin1.01.02.71.51.31.6-1.3-1.30.91.2-0.3-1.0-0.0-1.0-0.90.80.5-0.90.70.7-0.7-0.7
Diff in mean of infusions in LGA sessions1.51.64.4-2.1-2.1-1.92.12.1-1.9-1.91.10.40.90.40.3-0.20.20.4-0.1-0.00.10.0
Delay discount exponential model param0.10.10.2-0.1-0.2-0.10.20.2-0.1-0.10.3-0.30.3-0.4-0.30.30.4-0.30.30.3-0.3-0.4
Extinction: sum of active levers before priming0.20.20.6-0.3-0.50.20.50.5-0.8-0.50.5-0.20.5-0.3-0.40.70.5-0.50.40.4-0.4-0.4
Active lever presses in extinction session 63.83.76.72.32.51.4-2.6-2.62.32.5-2.51.1-2.31.11.3-0.9-1.71.1-1.6-1.61.61.6
Bone: final force0.00.00.2-0.1-0.0-0.2-0.00.00.30.50.0-0.30.1-0.1-0.0-0.20.2-0.30.00.00.00.0
Bone: final moment0.00.10.30.00.10.0-0.1-0.10.30.50.1-0.50.2-0.3-0.2-0.00.4-0.50.20.2-0.2-0.2
Food consumed during 24 hour testing period1.41.74.91.72.11.9-2.0-2.21.72.2-1.40.4-1.30.1-0.2-0.5-0.40.7-0.2-0.20.20.3
Glucose0.10.10.50.50.50.5-0.5-0.50.70.1-0.30.3-0.30.30.20.1-0.40.2-0.1-0.20.10.1
Heart weight0.40.51.51.21.20.9-1.2-1.21.21.2-0.5-0.4-0.4-0.3-0.20.10.0-0.30.20.2-0.2-0.2
Delay discount hyperbolic model param0.10.10.2-0.3-0.4-0.40.30.4-0.2-0.20.3-0.20.3-0.2-0.10.00.3-0.20.20.2-0.2-0.2
Intermittent access intake day 1-15 change1.71.63.91.51.71.1-1.7-1.71.92.0-1.60.6-1.50.80.7-0.7-1.20.7-0.9-0.90.90.9
Intermittent access intake escalation1.91.94.41.72.01.3-1.9-2.02.02.1-1.70.6-1.50.70.7-0.6-1.20.6-0.8-0.90.80.9
Intermittent access intake escalation 20.30.30.90.80.90.7-0.8-0.90.81.0-0.6-0.0-0.50.00.1-0.1-0.30.0-0.1-0.10.10.1
Intermitt. access day 1 inactive lever presses0.30.30.7-0.9-0.8-0.70.80.8-0.8-0.80.50.20.30.20.2-0.1-0.20.4-0.0-0.00.00.0
Intermitt. access day 15 inactive lever presses0.20.30.7-0.10.0-0.3-0.1-0.10.00.3-0.40.7-0.50.60.6-0.5-0.80.8-0.6-0.60.60.6
Intermitt. access escalation Index0.00.00.0-0.00.1-0.1-0.0-0.10.20.1-0.0-0.2-0.0-0.0-0.1-0.20.1-0.10.00.00.00.0
Intermittent access day 1 total infusions0.30.40.90.60.50.9-0.4-0.40.40.50.2-0.70.3-0.7-0.80.40.6-0.60.70.7-0.7-0.7
Intermittent access day 15 total infusions1.21.43.81.51.81.4-1.7-1.81.91.9-1.30.3-1.20.40.3-0.5-0.70.5-0.4-0.50.40.5
Intermittent access terminal intake (last 3 days)0.60.62.01.21.31.1-1.2-1.21.41.4-0.7-0.2-0.6-0.1-0.1-0.1-0.3-0.10.00.0-0.0-0.0
Intermittent access total infusions0.20.30.70.70.70.9-0.7-0.70.80.8-0.3-0.3-0.2-0.3-0.40.10.2-0.20.30.3-0.3-0.3
Intermittent access day 1 locomotion0.10.10.30.00.2-0.1-0.1-0.20.50.4-0.40.4-0.40.30.4-0.4-0.40.5-0.3-0.30.30.3
Intermittent access day 15 total locomotion0.91.02.51.51.61.3-1.5-1.51.61.4-1.10.2-0.90.20.10.0-0.50.3-0.3-0.40.30.3
Intermittent access total locomotion0.20.30.90.80.70.9-0.6-0.70.70.8-0.3-0.3-0.2-0.3-0.30.4-0.0-0.20.20.2-0.2-0.2
Intermittent access standard deviation0.10.10.20.10.10.4-0.1-0.1-0.00.00.2-0.30.2-0.4-0.30.40.4-0.20.40.4-0.4-0.4
Left kidney weight1.33.56.61.00.52.1-0.5-0.40.0-0.31.4-2.51.7-2.4-2.62.62.3-2.12.32.3-2.3-2.3
Right kidney weight0.92.44.60.70.31.7-0.2-0.2-0.1-0.41.3-2.01.5-1.9-2.22.12.0-1.51.91.9-1.9-1.9
Cocaine induced anxiety1.01.23.3-1.7-1.7-1.71.61.6-1.8-1.40.70.60.50.60.5-0.5-0.10.5-0.3-0.30.40.3
Post-drug Anxiety0.30.31.0-0.9-0.9-0.80.80.7-1.0-0.50.30.30.20.50.3-0.4-0.00.4-0.2-0.20.20.2
Baseline Anxiety0.91.02.61.51.61.6-1.5-1.61.61.5-0.8-0.4-0.6-0.2-0.30.1-0.1-0.20.20.1-0.1-0.1
Tail length4.513.623.20.9-0.33.10.40.5-1.8-1.53.3-4.73.7-4.7-4.84.44.6-4.74.74.7-4.7-4.7
Length with tail2.17.812.60.2-0.72.00.80.8-1.7-1.42.9-3.53.1-3.5-3.63.43.4-3.13.53.5-3.5-3.5
Length without tail0.30.61.9-0.4-0.2-0.70.20.20.30.2-0.51.0-0.61.01.0-0.6-1.01.4-1.0-1.01.01.0
Times rat made contact with spout1.11.22.0-0.9-1.1-0.11.21.1-1.4-1.11.4-0.91.3-1.0-1.00.61.3-0.91.31.3-1.3-1.3
Lifetime Intake0.30.41.00.91.01.0-0.9-0.91.00.9-0.4-0.3-0.3-0.2-0.30.10.1-0.10.20.2-0.2-0.2
Liver weight, left1.11.83.3-1.2-1.2-0.11.31.2-1.4-1.11.8-1.21.8-1.3-1.11.21.5-1.11.51.5-1.5-1.5
Liver weight, right3.04.98.7-2.2-2.5-0.62.52.6-2.6-2.33.0-1.82.9-1.9-1.92.12.4-1.72.12.1-2.1-2.1
Locomotor activity0.50.82.71.31.11.6-1.1-1.10.80.7-0.2-0.8-0.0-0.8-1.00.60.5-0.70.90.9-0.9-0.9
Locomotor testing distance1.42.46.32.01.62.5-1.6-1.51.00.80.1-1.70.4-1.7-1.81.81.2-1.61.51.5-1.5-1.5
Locomotor testing rearing1.72.65.20.90.21.7-0.2-0.1-0.3-0.61.2-2.11.5-2.1-2.12.31.7-2.02.02.0-2.0-2.0
Locomotion in novel chamber1.01.22.71.41.60.9-1.6-1.61.61.5-1.30.4-1.20.50.7-0.3-0.90.4-0.8-0.80.80.8
Locomotion in novel chamber post-restriction3.23.98.12.72.81.7-2.8-2.82.62.7-2.50.9-2.30.91.0-0.8-1.60.9-1.4-1.41.41.4
Fecal boli incidents, locomotor time 10.60.71.51.01.20.7-1.2-1.21.11.2-1.00.4-0.90.40.5-0.5-0.70.4-0.5-0.50.50.5
Change in fecal boli incidents, locomotor task0.50.51.2-1.1-1.0-1.11.00.9-0.8-0.80.30.60.10.70.6-0.5-0.40.6-0.3-0.30.30.3
Time >=10cm from walls, locomotor time 11.61.63.41.71.80.9-1.8-1.91.71.4-1.60.5-1.50.60.8-0.7-1.10.4-0.9-0.90.90.9
Bouts of movement, locomotor time 10.10.10.20.40.40.5-0.4-0.40.3-0.0-0.30.2-0.30.10.10.2-0.2-0.0-0.3-0.30.30.3
Total resting periods, locomotor time 10.30.30.50.20.40.1-0.4-0.40.5-0.0-0.60.7-0.60.60.7-0.3-0.60.5-0.7-0.70.70.7
Rest time, locomotor task time 10.70.82.0-0.20.0-0.30.0-0.1-0.0-0.0-0.71.4-0.91.11.1-0.8-1.01.4-1.2-1.21.21.2
Distance moved, locomotor task time 11.51.63.40.2-0.10.80.10.2-0.3-0.21.2-1.81.3-1.7-1.71.51.5-1.61.61.6-1.6-1.6
Vertical activity count, locomotor time 11.01.02.60.70.40.8-0.4-0.30.30.60.6-1.60.8-1.4-1.41.11.1-1.51.21.2-1.2-1.2
Time >=10cm from walls, locomotor time 20.50.51.71.31.11.3-1.1-1.10.80.5-0.4-0.3-0.3-0.3-0.30.80.1-0.40.10.1-0.1-0.1
Bouts of movement, locomotor time 20.20.31.30.90.71.1-0.6-0.70.30.1-0.1-0.3-0.0-0.5-0.40.70.4-0.40.30.2-0.3-0.2
Total resting periods, locomotor time 20.10.10.70.60.50.8-0.5-0.50.20.0-0.2-0.1-0.1-0.2-0.20.40.2-0.20.10.1-0.1-0.0
Rest time, locomotor task time 21.01.23.2-1.8-1.7-1.71.71.5-1.5-1.10.50.80.30.70.7-1.1-0.30.7-0.4-0.40.40.4
Distance moved, locomotor task time 21.51.74.72.01.62.2-1.7-1.51.21.1-0.1-1.40.2-1.4-1.41.90.9-1.00.80.8-0.8-0.8
Vertical activity count, locomotor time 21.51.73.61.20.81.5-0.8-0.60.30.50.6-1.80.8-1.7-1.71.91.4-1.81.41.4-1.4-1.4
Light reinforcement 10.81.54.5-2.1-2.0-1.72.02.0-1.8-1.41.20.21.00.00.10.00.40.30.10.1-0.1-0.1
Light reinforcement 20.30.40.8-0.10.1-0.2-0.1-0.10.30.6-0.50.8-0.60.70.7-0.4-0.60.9-0.8-0.80.80.8
Bone: marrow area1.12.44.60.90.51.7-0.4-0.4-0.00.11.1-2.21.3-2.1-2.11.81.9-2.01.91.9-1.9-1.9
Bone: maximum diameter1.22.24.41.81.52.1-1.4-1.31.01.20.2-2.00.6-1.8-1.71.61.4-1.81.31.3-1.3-1.3
Bone: maximum force0.00.10.60.10.3-0.0-0.3-0.30.40.8-0.2-0.3-0.1-0.1-0.0-0.30.2-0.3-0.1-0.10.10.1
Bone: maximum moment0.10.10.60.30.40.2-0.4-0.40.40.8-0.1-0.5-0.0-0.3-0.2-0.20.4-0.50.10.1-0.1-0.1
Mean time between licks in bursts2.94.111.02.01.53.3-1.4-1.41.01.20.7-2.31.0-2.6-2.82.62.2-1.92.12.1-2.1-2.1
Mean num. licks in bursts1.31.64.72.22.02.1-1.9-2.01.41.8-1.0-0.7-0.7-0.5-0.70.50.2-0.70.40.4-0.4-0.4
Cd content in liver0.91.02.6-1.1-1.2-0.91.21.3-1.3-1.61.3-0.81.3-0.7-0.70.60.9-0.80.70.7-0.7-0.7
Co content in liver1.21.42.60.80.21.2-0.2-0.2-0.6-0.40.9-1.51.0-1.4-1.61.41.4-1.41.51.5-1.5-1.5
Cu content in liver0.80.92.90.70.21.3-0.2-0.1-0.4-0.20.7-1.10.8-1.2-1.21.71.0-1.01.11.1-1.1-1.1
Fe content in liver0.00.00.3-0.0-0.2-0.10.20.3-0.6-0.00.2-0.20.2-0.1-0.00.30.1-0.30.10.1-0.1-0.1
K content in liver0.30.30.7-0.7-0.7-0.40.80.7-0.8-0.60.6-0.20.5-0.2-0.20.10.30.00.50.5-0.5-0.5
Mg content in liver0.00.00.20.40.30.4-0.3-0.30.10.2-0.2-0.1-0.1-0.1-0.10.20.00.10.00.0-0.0-0.0
Mn content in liver1.31.52.9-1.1-0.7-1.50.70.7-0.1-0.2-0.71.7-0.91.61.6-1.4-1.41.6-1.4-1.41.41.4
Na content in liver1.01.01.70.70.90.4-0.8-0.91.21.3-1.31.0-1.30.90.9-1.0-1.11.2-1.0-1.01.01.0
Rb content in liver0.50.61.30.80.51.1-0.5-0.40.00.10.3-1.10.5-0.9-0.91.00.7-1.00.90.9-0.9-0.9
Se content in liver2.02.46.3-2.3-2.0-2.52.01.9-1.5-1.60.41.7-0.01.51.5-1.2-0.91.6-1.1-1.11.11.1
Sr content in liver0.20.20.30.20.3-0.1-0.3-0.30.30.2-0.50.5-0.50.50.5-0.3-0.50.4-0.5-0.50.50.5
Zn content in liver2.02.27.22.72.22.6-2.2-2.11.71.9-1.0-1.0-0.6-1.0-1.11.10.4-0.80.50.4-0.5-0.4
Bone: minimum diameter1.93.66.3-0.1-0.50.90.50.6-1.1-0.92.0-2.52.1-2.4-2.42.22.5-2.42.32.3-2.3-2.3
Time in familiar zone, hab. session 10.20.10.5-0.6-0.5-0.50.60.5-0.7-0.30.5-0.10.4-0.1-0.0-0.00.30.10.20.2-0.2-0.2
Time in novel zone, hab. session 10.20.20.6-0.1-0.20.10.20.3-0.0-0.60.5-0.50.5-0.5-0.50.60.5-0.80.50.5-0.5-0.5
Total zone transitions, hab. session 10.81.11.70.50.8-0.1-0.8-0.81.20.9-1.21.0-1.21.11.1-1.3-1.31.1-1.1-1.11.11.1
Total locomotion distance, hab. session 11.41.93.3-1.3-1.7-0.71.71.8-1.7-1.81.8-1.11.7-1.1-1.11.21.3-0.91.21.2-1.2-1.2
Locomotion velocity, hab. session 10.91.22.1-0.9-1.4-0.51.31.5-1.4-1.41.4-0.91.3-0.9-1.01.01.1-0.81.01.0-1.0-1.0
Time in familiar zone, hab. session 20.70.81.60.60.50.9-0.5-0.50.10.50.4-1.30.5-1.1-1.10.80.9-1.21.11.1-1.1-1.1
Time in novel zone, hab. session 20.40.40.8-0.00.1-0.1-0.1-0.10.5-0.2-0.50.9-0.50.80.8-0.2-0.70.8-0.9-0.90.90.9
Total zone transitions, hab. session 21.82.34.41.51.80.7-1.8-1.72.11.9-1.90.9-1.81.01.0-0.8-1.41.4-1.6-1.61.61.6
Total locomotion distance, hab. session 20.81.01.8-0.7-0.9-0.20.91.1-1.0-0.81.3-1.11.3-1.3-1.11.31.3-0.60.80.9-0.8-0.9
Locomotion velocity, hab. session 20.91.22.1-0.8-1.1-0.21.11.2-1.1-0.91.4-1.11.4-1.4-1.21.41.4-0.61.01.0-1.0-1.0
Novel to familiar place preference ratio0.20.20.30.50.40.4-0.3-0.40.10.6-0.60.4-0.50.30.4-0.1-0.40.5-0.6-0.60.60.6
Novelty place preference0.10.10.20.50.30.4-0.2-0.3-0.00.4-0.50.4-0.40.30.30.0-0.30.5-0.5-0.50.50.5
Time in novel zone, NPP test0.20.20.40.60.50.6-0.4-0.50.20.6-0.60.3-0.50.30.30.0-0.40.4-0.5-0.50.50.5
Total zone transitions, NPP test0.81.11.90.40.70.0-0.7-0.71.20.9-1.21.1-1.21.11.1-1.0-1.21.4-1.3-1.31.31.3
Total locomotion distance, NPP test0.81.02.7-1.3-1.5-0.81.51.6-1.3-1.41.3-0.41.2-0.7-0.71.10.90.00.40.4-0.4-0.4
Locomotion velocity, NPP test0.91.33.5-1.6-1.7-1.01.71.9-1.6-1.61.4-0.31.3-0.7-0.61.10.90.10.30.3-0.3-0.3
Intraocular pressure0.81.12.41.11.30.4-1.3-1.31.61.2-1.30.7-1.30.70.8-0.7-1.10.5-0.8-0.80.80.8
Delta distance traveled before/after self-admin0.50.60.90.40.5-0.1-0.5-0.60.60.6-0.90.9-0.90.80.8-0.8-0.90.9-0.9-0.90.90.9
Delta ambulatory time before/after self-admin1.21.31.90.50.7-0.3-0.7-0.80.80.9-1.31.3-1.41.31.3-1.2-1.41.3-1.3-1.31.31.3
Parametrial fat weight0.91.83.2-1.2-1.4-0.41.41.5-1.2-1.51.8-1.41.8-1.2-1.01.01.5-1.51.41.4-1.4-1.4
Pavlov. Cond. lever latency0.30.41.3-0.9-0.7-1.10.70.7-0.3-0.5-0.00.7-0.10.60.8-0.5-0.50.5-0.7-0.60.70.6
Pavlov. Cond. magazine entry latency1.01.23.31.71.31.8-1.3-1.20.91.0-0.1-1.40.2-1.3-1.21.30.9-1.10.70.7-0.7-0.7
Pavlov. Cond. change in total contacts0.30.31.00.90.81.0-0.8-0.70.70.5-0.2-0.4-0.1-0.4-0.40.70.3-0.20.10.1-0.1-0.1
Pavlov. Cond. index score1.11.43.51.51.11.9-1.1-1.00.60.60.2-1.50.5-1.4-1.51.41.1-1.31.11.1-1.1-1.1
Pavlov. Cond. latency score1.01.33.31.51.11.8-1.1-1.10.60.70.1-1.40.3-1.3-1.41.31.0-1.21.01.0-1.0-1.0
Pavlov. Cond. lever contacts0.60.71.40.70.41.2-0.3-0.30.0-0.00.5-1.10.6-0.9-1.20.90.9-0.91.01.0-1.0-1.0
Pavlov. Cond. magazine entry number1.11.43.9-1.9-1.6-2.01.61.5-1.2-1.20.31.30.01.11.1-1.2-0.71.1-0.7-0.70.70.7
Pavlov. Cond. intertrial magazine entries0.60.72.7-1.4-1.2-1.21.21.2-0.7-1.60.60.80.30.70.5-0.2-0.30.5-0.2-0.20.20.2
Pavlov. Cond. lever-magazine prob. diff.0.91.12.61.31.01.6-0.9-0.90.50.60.2-1.40.4-1.2-1.31.11.0-1.11.01.0-1.0-1.0
Pavlov. Cond. response bias0.50.61.30.70.41.1-0.3-0.30.10.00.4-1.10.6-0.9-1.10.90.9-0.90.90.9-0.9-0.9
Pavlov. Cond. lever latency8.010.830.4-5.5-5.3-5.45.25.2-4.6-4.82.51.61.81.61.6-1.3-0.41.0-0.2-0.10.20.1
Pavlov. Cond. magazine entry latency2.73.17.82.82.82.1-2.8-2.82.62.7-1.9-0.2-1.6-0.10.1-0.3-0.6-0.1-0.7-0.70.70.7
Pavlov. Cond. change in total contacts6.18.424.04.94.74.5-4.7-4.64.33.9-2.5-1.1-1.9-1.1-1.01.1-0.1-0.6-0.3-0.30.30.3
Pavlov. Cond. index score6.68.424.14.94.74.5-4.7-4.64.14.2-2.5-1.3-1.9-1.2-1.10.90.0-0.8-0.1-0.20.10.2
Pavlov. Cond. latency score6.27.821.74.74.64.2-4.5-4.44.14.1-2.5-1.0-1.9-0.9-0.80.7-0.2-0.5-0.3-0.40.30.4
Pavlov. Cond. lever contacts8.511.732.35.75.55.5-5.4-5.34.94.9-2.6-1.8-1.9-1.7-1.61.40.4-1.10.30.2-0.3-0.2
Pavlov. Cond. magazine entry number3.74.613.0-3.6-3.5-2.93.53.4-3.1-3.02.20.41.80.30.2-0.30.70.20.70.7-0.7-0.7
Pavlov. Cond. intertrial magazine entries1.82.43.9-0.5-0.90.51.01.0-1.2-1.11.7-1.61.8-1.7-1.71.81.9-1.62.02.0-2.0-2.0
Pavlov. Cond. lever-magazine prob. diff.6.17.722.34.74.54.4-4.5-4.43.94.0-2.3-1.2-1.7-1.2-1.11.00.1-0.8-0.1-0.20.10.2
Pavlov. Cond. response bias8.511.632.85.75.55.5-5.4-5.34.84.8-2.7-1.7-1.9-1.6-1.61.30.3-1.20.20.1-0.2-0.1
Time in closed arm before self-admin2.22.54.21.41.70.5-1.8-1.82.11.8-2.01.3-1.91.31.3-1.2-1.71.3-1.5-1.61.51.6
Time in closed arm after self-admin0.80.81.9-0.6-0.3-0.90.30.1-0.10.1-0.61.3-0.81.31.2-1.4-1.11.2-1.0-1.01.01.0
Time in open arm before self-admin1.31.44.0-2.0-2.0-1.71.92.0-1.7-1.71.10.30.90.30.2-0.20.20.20.10.1-0.1-0.1
Time in open arm after self-admin1.21.42.70.2-0.20.70.10.2-0.4-0.51.1-1.61.2-1.5-1.51.31.5-1.51.51.5-1.5-1.5
Bone: periosteal estimation1.22.55.21.10.71.8-0.7-0.50.20.31.0-2.31.3-2.1-2.12.11.9-2.21.81.8-1.8-1.8
Bone: periosteal perimeter1.22.03.61.21.01.8-0.9-0.90.50.70.6-1.90.9-1.7-1.81.51.6-1.81.71.6-1.7-1.6
Bone: post-yield work0.10.20.50.40.60.3-0.6-0.70.60.7-0.2-0.4-0.1-0.2-0.2-0.40.3-0.30.20.2-0.2-0.2
Progressive ratio test 1 active lever presses0.10.10.3-0.5-0.3-0.50.40.3-0.10.1-0.10.5-0.20.40.4-0.5-0.40.4-0.3-0.30.30.3
Progressive ratio test 1 breakpoint0.10.10.3-0.5-0.4-0.60.50.4-0.10.0-0.00.4-0.10.30.4-0.5-0.30.4-0.2-0.20.20.2
Progressive ratio test 1 inactive lever presses0.00.00.10.20.20.1-0.1-0.10.20.3-0.0-0.20.0-0.2-0.20.00.1-0.00.10.1-0.1-0.1
Progressive ratio test 2 active lever presses0.70.72.41.31.11.6-0.9-0.90.80.8-0.2-0.80.0-0.8-0.80.90.5-0.70.70.6-0.7-0.7
Progressive ratio test 2 breakpoint0.60.62.11.21.01.4-0.9-0.80.70.8-0.1-0.80.1-0.8-0.80.90.5-0.70.70.6-0.7-0.6
Progressive ratio test 2 inactive lever presses0.30.31.00.90.71.0-0.7-0.70.50.6-0.2-0.5-0.1-0.5-0.50.50.1-0.40.40.4-0.4-0.4
Incentive Sensitization - Responses1.31.34.01.81.42.0-1.3-1.31.01.1-0.2-1.20.1-1.1-1.21.10.7-1.00.90.9-0.9-0.9
Incentive Sensitization - Breakpoint1.21.23.81.81.51.9-1.4-1.31.01.2-0.3-1.1-0.1-0.9-1.01.00.6-0.90.70.7-0.7-0.7
Sum of active levers in priming session hrs 5-60.00.00.20.0-0.10.20.10.1-0.5-0.20.00.10.00.10.10.2-0.00.1-0.1-0.10.10.1
Progressive ratio0.30.40.60.40.4-0.1-0.4-0.40.50.8-0.80.6-0.80.60.6-0.7-0.70.7-0.8-0.80.80.8
Food seeking constrained by brief footshock0.91.13.51.31.11.9-1.1-1.10.70.90.0-1.10.2-1.0-1.11.10.9-1.00.90.9-0.9-0.9
Seeking ratio, punishment vs. effort1.11.42.40.60.41.4-0.4-0.4-0.0-0.10.8-1.51.0-1.5-1.51.51.5-1.41.51.4-1.5-1.4
Retroperitoneal fat weight5.718.630.7-3.7-4.5-1.44.64.9-4.7-5.05.5-3.75.4-3.7-3.64.34.6-3.94.14.2-4.2-4.2
Reaction time number correct1.11.52.20.30.9-0.3-0.9-1.01.20.9-1.41.4-1.51.41.3-1.4-1.41.4-1.5-1.51.51.5
Reaction time mean minus median0.81.12.51.20.91.6-0.8-0.80.80.70.2-1.30.4-1.1-1.11.10.8-1.51.21.1-1.2-1.1
Reaction time mean minus median AUC0.70.92.61.41.31.6-1.2-1.21.21.3-0.4-0.7-0.2-0.6-0.60.60.2-0.90.60.5-0.6-0.6
Reaction time num false alarms1.31.84.9-2.1-2.2-1.72.12.2-1.9-1.81.5-0.21.3-0.4-0.30.40.8-0.20.40.5-0.4-0.5
Reaction time num false alarms AUC0.70.92.7-1.6-1.6-1.41.61.6-1.3-1.30.90.20.70.10.10.10.30.20.00.1-0.1-0.1
Reaction time trials correct on left1.11.52.20.30.9-0.3-0.9-1.01.20.9-1.41.4-1.51.41.3-1.4-1.41.4-1.5-1.51.51.5
Reaction time trials on left1.11.62.30.40.9-0.3-0.9-1.01.31.0-1.41.5-1.51.41.4-1.4-1.41.5-1.5-1.51.51.5
Reaction time mean0.40.50.8-0.6-0.9-0.00.90.9-0.9-0.60.9-0.60.9-0.6-0.50.50.7-0.80.80.8-0.8-0.8
Reaction time mean AUC0.30.51.3-0.9-1.1-0.31.11.0-1.1-0.70.8-0.20.7-0.3-0.20.20.4-0.40.50.5-0.5-0.5
Median of all reaction times0.40.51.6-1.1-1.2-0.61.21.1-1.2-0.80.8-0.10.7-0.20.0-0.00.3-0.20.30.3-0.3-0.3
Reaction time omissions0.10.10.4-0.2-0.20.10.10.20.1-0.00.5-0.40.5-0.4-0.20.50.3-0.70.30.3-0.3-0.3
Reaction time false alarm rate1.11.64.1-1.8-2.0-1.32.02.0-1.9-1.61.5-0.41.3-0.5-0.40.60.9-0.40.60.6-0.6-0.6
Reaction time premature initiation rate2.93.88.40.80.31.6-0.3-0.1-0.0-0.31.6-2.91.9-2.6-2.52.42.4-2.82.42.4-2.4-2.4
Reaction time premature initiations1.11.53.31.00.91.3-0.9-0.80.80.40.5-1.80.8-1.6-1.51.41.3-1.71.31.3-1.3-1.3
Std. dev. reaction times1.21.64.20.50.11.20.00.0-0.2-0.21.0-1.71.2-1.5-1.51.51.4-2.11.61.6-1.6-1.6
Reaction time trials completed1.11.62.30.40.9-0.3-0.9-1.01.31.0-1.41.5-1.51.41.4-1.4-1.41.5-1.5-1.51.51.5
Reaction time trials AUC0.81.21.70.40.9-0.2-0.9-1.01.20.9-1.21.2-1.31.21.1-1.1-1.21.2-1.3-1.31.31.3
Run reversals in cocaine runway, females5.45.38.0-1.2-1.80.11.81.9-2.2-2.02.8-2.62.8-2.4-2.52.22.6-2.32.72.7-2.6-2.7
Run reversals in cocaine runway, males0.10.10.4-0.1-0.0-0.10.0-0.1-0.10.3-0.20.3-0.30.30.4-0.6-0.20.3-0.2-0.20.20.2
Latency to leave start box in cocaine runway0.80.82.6-1.6-1.4-1.41.41.4-1.1-1.20.60.60.40.60.5-0.4-0.00.5-0.4-0.30.40.4
Latency to leave start box in cocaine runway, F0.70.72.1-1.5-1.4-1.11.41.4-1.2-1.21.00.00.80.0-0.10.20.50.00.10.1-0.1-0.1
Latency to leave start box in cocaine runway, M0.60.61.4-0.5-0.1-0.90.10.00.20.1-0.61.0-0.71.11.1-1.2-0.90.9-0.9-0.90.90.9
Std. dev. time between licks in bursts1.61.93.90.60.31.6-0.2-0.20.1-0.21.1-1.71.2-1.7-2.01.81.7-1.61.71.7-1.7-1.7
Total sessions with >9 infusions1.21.33.51.71.81.3-1.8-1.81.91.8-1.3-0.0-1.10.20.1-0.3-0.50.1-0.4-0.40.40.4
Short access day 1 total inactive lever presses0.00.00.2-0.3-0.2-0.00.30.2-0.0-0.20.10.30.10.20.2-0.1-0.20.50.00.0-0.1-0.0
Short access day 10 total inactive lever presses0.10.10.3-0.3-0.3-0.50.20.2-0.4-0.2-0.10.4-0.10.40.4-0.4-0.40.4-0.3-0.30.30.3
Short access day 1 total infusions0.90.93.01.61.51.7-1.4-1.51.41.3-0.6-0.6-0.4-0.5-0.60.30.3-0.30.40.4-0.4-0.4
Short access day 10 total infusions0.30.30.70.70.60.9-0.5-0.50.50.30.1-0.70.2-0.6-0.70.50.6-0.50.50.5-0.5-0.5
Short access total infusions0.20.20.60.60.60.8-0.5-0.50.60.6-0.1-0.50.0-0.4-0.50.20.4-0.20.40.4-0.4-0.4
Short access day 1 locomotion2.93.15.81.92.21.0-2.3-2.32.42.4-2.21.1-2.11.21.2-1.1-1.61.2-1.4-1.41.41.4
Short access day 10 total locomotion0.10.10.50.70.60.6-0.5-0.50.50.5-0.2-0.2-0.1-0.3-0.30.50.1-0.20.10.1-0.1-0.1
Short access total locomotion0.20.20.50.40.50.1-0.5-0.50.70.7-0.60.4-0.60.40.4-0.4-0.60.5-0.5-0.50.50.5
One hour access (0.3 mA shock)0.80.92.91.71.41.6-1.4-1.31.01.0-0.5-0.8-0.3-0.7-0.70.80.3-0.80.40.4-0.4-0.4
Compulsive drug intake0.30.30.40.60.60.1-0.6-0.50.70.2-0.60.4-0.60.50.40.0-0.60.2-0.6-0.60.60.6
One hour access (shock baseline)0.50.51.71.21.11.3-1.0-1.10.91.1-0.5-0.5-0.3-0.4-0.40.20.0-0.30.30.3-0.3-0.3
Social response proportion0.40.51.3-0.9-1.1-0.51.11.0-1.1-0.90.8-0.10.7-0.3-0.30.20.50.10.30.3-0.3-0.3
Social responses1.41.72.9-1.3-1.5-0.61.61.6-1.5-1.71.7-1.01.6-1.1-1.11.11.3-0.81.21.2-1.2-1.2
Social time1.41.84.3-2.0-1.7-2.11.61.6-1.3-1.30.21.5-0.11.21.3-0.8-0.91.5-1.2-1.11.21.1
Soleus weight1.74.97.4-1.0-1.70.21.81.8-2.2-1.72.6-2.52.7-2.4-2.52.12.7-2.22.52.5-2.5-2.5
Bone: stiffness0.10.10.4-0.6-0.5-0.50.50.5-0.40.30.3-0.30.3-0.2-0.1-0.20.50.10.00.00.00.0
Tibialis anterior weight0.20.61.40.2-0.10.50.10.1-0.5-0.20.7-1.20.9-1.1-1.00.91.1-0.90.90.8-0.8-0.8
Time to tail flick, vehicle, before self-admin0.50.50.9-0.7-0.9-0.60.80.9-0.8-1.00.8-0.60.8-0.5-0.50.30.6-0.70.50.5-0.5-0.5
Time to tail flick, vehicle, after self-admin1.01.02.71.51.61.1-1.6-1.61.61.6-1.10.0-1.00.10.2-0.3-0.50.2-0.3-0.40.30.4
Time to tail flick, test, before self-admin0.30.30.60.1-0.00.40.00.1-0.1-0.20.5-0.80.6-0.8-0.80.70.6-0.80.70.7-0.7-0.7
Time to tail flick, test, after self-admin0.70.71.40.30.00.90.00.0-0.3-0.50.7-1.00.8-1.1-1.11.21.0-0.71.01.0-1.0-1.0
Delta time to tail flick, vehicle, before/after SA2.72.75.52.02.31.3-2.3-2.32.32.3-2.00.8-1.90.80.9-0.8-1.30.9-1.1-1.11.11.1
Delta time to tail flick, test, before/after SA0.20.10.7-0.2-0.1-0.20.10.0-0.1-0.2-0.20.6-0.30.50.5-0.3-0.40.9-0.4-0.40.40.4
Tibia length1.23.49.02.52.71.5-2.7-2.63.02.4-2.30.6-2.01.00.8-0.6-1.60.8-1.3-1.31.31.3
Ambulatory time before self-admin0.30.30.7-0.8-0.7-0.80.70.6-0.7-0.30.00.7-0.10.70.6-0.6-0.40.5-0.5-0.50.50.5
Ambulatory time after self-admin1.61.83.9-0.7-0.4-1.30.40.2-0.20.0-1.02.0-1.21.81.8-1.6-1.61.9-1.6-1.61.61.6
Bone: tissue strength2.12.03.4-0.10.3-1.2-0.4-0.40.80.8-1.41.6-1.51.81.9-1.8-1.81.5-1.8-1.81.81.8
Total heroin consumption0.10.10.20.30.30.2-0.3-0.30.20.5-0.40.2-0.40.30.3-0.2-0.40.4-0.5-0.50.50.5
Bone: trabecular number0.50.73.5-1.5-1.2-1.91.21.1-0.7-0.90.40.40.30.60.7-1.1-0.2-0.2-0.2-0.20.20.2
Bone: trabecular spacing0.91.12.71.61.61.5-1.6-1.61.41.3-1.20.4-1.00.40.30.1-0.70.6-0.5-0.50.50.5
Bone: trabecular thickness0.91.11.6-0.8-1.0-0.41.01.0-1.2-1.11.3-1.01.3-1.0-0.90.81.3-1.11.11.1-1.1-1.1
Bone: trabecular tissue density1.11.52.7-1.3-1.6-0.41.61.6-1.6-1.21.6-0.81.5-1.0-1.01.01.3-0.61.01.0-1.0-1.0
Water consumed over 24 hours0.50.61.8-1.4-1.3-1.21.31.2-1.2-1.10.60.40.40.30.3-0.6-0.00.30.00.1-0.0-0.0
Number of responses in last shaping day0.80.91.7-0.1-0.50.20.40.6-0.6-0.71.1-1.31.1-1.2-1.11.01.0-1.01.11.1-1.1-1.1