Hub : Traits

Patch foraging water rate 18 sec

Delay discounting using a sequential patch depletion procedure, water consumption rate during the last two sessions with an experimenter-imposed delay of 18 sec

Tags: Behavior · Delay discounting

Project: p50_david_dietz

1 locus · 2 genes with independent associations · 10 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr1	140610199	142727457	10	2	1.37e-10	3.55e-09	1e+00	Grm5 LOC102554680

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
Liver weight, right	6.59	1	0	0	-0.99	6.20e-04	Grm5
Retroperitoneal fat weight	2.88	1	0	0	0	1.00e+00	Grm5
Intraocular pressure	12.61	3	0	0	1	2.00e-21	Ctsc Grm5 LOC102554680
Mean time between licks in bursts	7.65	3	0	0	-1	1.02e-14	Ctsc Grm5 LOC102554680
Patch foraging time to switch 0 sec	8.77	3	0	0	-1	2.23e-18	Ctsc Grm5 LOC102554680
Patch foraging water rate 0 sec	6.55	1	0	0	1	2.73e-04	Grm5
Patch foraging water rate 12 sec	12.97	3	1	50	1	9.94e-20	Ctsc Grm5 LOC102554680
Patch foraging water rate 24 sec	7	2	0	0	1	7.67e-15	Ctsc Grm5
Patch foraging water rate 6 sec	7.63	2	0	0	1	3.15e-21	Ctsc Grm5
Locomotor activity	5.79	2	0	0	0	1.00e+00	Ctsc Grm5
Light reinforcement 1	11.66	3	0	0	-1	2.65e-18	Ctsc Grm5 LOC102554680
Light reinforcement 2	21.39	3	3	150	-0.99	1.39e-16	Ctsc Grm5 LOC102554680
Reaction time num false alarms	13.97	3	0	0	-1	2.11e-21	Ctsc Grm5 LOC102554680
Reaction time num false alarms AUC	10.75	3	0	0	-1	8.83e-22	Ctsc Grm5 LOC102554680
Reaction time false alarm rate	13.75	3	0	0	-1	2.58e-20	Ctsc Grm5 LOC102554680
Short access day 1 total infusions	9.4	2	0	0	-1	5.44e-04	Ctsc LOC102554680
Locomotion velocity, session 1	17.88	3	0	0	1	1.41e-19	Ctsc Grm5 LOC102554680
Locomotion velocity, session 2	8.27	3	0	0	1	6.86e-10	Ctsc Grm5 LOC102554680
Locomotion distance, session 3	9.36	3	0	0	1	1.34e-10	Ctsc Grm5 LOC102554680
Stereotopy head waving bouts, day 3	9.3	3	0	0	-1	1.47e-16	Ctsc Grm5 LOC102554680
Locomotion velocity, session 8	8.28	3	0	0	1	9.55e-17	Ctsc Grm5 LOC102554680
Total zone transitions, hab. session 1	7.85	3	0	0	1	1.79e-12	Ctsc Grm5 LOC102554680
Total locomotion distance, hab. session 1	29.24	3	3	150	-1	4.91e-18	Ctsc Grm5 LOC102554680
Locomotion velocity, hab. session 1	30	3	3	150	-1	1.46e-17	Ctsc Grm5 LOC102554680
Total locomotion distance, hab. session 2	35.8	3	3	150	-1	9.73e-18	Ctsc Grm5 LOC102554680
Locomotion velocity, hab. session 2	33.18	3	3	150	-1	8.45e-18	Ctsc Grm5 LOC102554680
Total locomotion distance, NPP test	39.71	3	3	150	-0.99	2.86e-16	Ctsc Grm5 LOC102554680
Locomotion velocity, NPP test	38.37	3	3	150	-0.99	1.34e-16	Ctsc Grm5 LOC102554680
Vertical activity count, locomotor time 2	9.16	1	0	0	0	1.00e+00	Grm5
Latency to leave start box in cocaine runway	11.39	2	0	0	-1	2.62e-08	Ctsc Grm5
Latency to leave start box in cocaine runway, F	8.69	1	0	0	0	1.00e+00	Grm5
Latency to leave start box in cocaine runway, M	9.9	1	0	0	-1	2.22e-03	Grm5
Cd content in liver	8.18	1	0	0	0	1.00e+00	Grm5

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.35
Adipose	alternative TSS	0	0	1.29
Adipose	gene expression	0	0	1.31
Adipose	isoform ratio	0	0	1.35
Adipose	intron excision ratio	0	0	1.27
Adipose	mRNA stability	0	0	1.29
BLA	alternative polyA	0	0	1.33
BLA	alternative TSS	0	0	1.38
BLA	gene expression	1	0	1.32
BLA	isoform ratio	2	0.1	1.41
BLA	intron excision ratio	0	0	1.36
BLA	mRNA stability	0	0	1.37
Brain	alternative polyA	2	0.1	1.26
Brain	alternative TSS	0	0	1.35
Brain	gene expression	1	0	1.36
Brain	isoform ratio	2	0	1.38
Brain	intron excision ratio	0	0	1.43
Brain	mRNA stability	1	0	1.35
Eye	alternative polyA	0	0	1.15
Eye	alternative TSS	0	0	1.27
Eye	gene expression	1	0.1	1.31
Eye	isoform ratio	0	0	1.34
Eye	intron excision ratio	0	0	1.24
Eye	mRNA stability	0	0	1.14
IL	alternative polyA	0	0	1.41
IL	alternative TSS	0	0	1.27
IL	gene expression	0	0	1.34
IL	isoform ratio	0	0	1.43
IL	intron excision ratio	0	0	1.34
IL	mRNA stability	0	0	1.39
LHb	alternative polyA	0	0	1.28
LHb	alternative TSS	0	0	1.57
LHb	gene expression	0	0	1.37
LHb	isoform ratio	0	0	1.46
LHb	intron excision ratio	0	0	1.28
LHb	mRNA stability	0	0	1.37
Liver	alternative polyA	0	0	1.36
Liver	alternative TSS	0	0	1.24
Liver	gene expression	1	0	1.35
Liver	isoform ratio	0	0	1.29
Liver	intron excision ratio	0	0	1.34
Liver	mRNA stability	0	0	1.32
NAcc	alternative polyA	0	0	1.36
NAcc	alternative TSS	0	0	1.37
NAcc	gene expression	1	0	1.35
NAcc	isoform ratio	3	0.1	1.41
NAcc	intron excision ratio	0	0	1.36
NAcc	mRNA stability	0	0	1.35
OFC	alternative polyA	0	0	1.33
OFC	alternative TSS	0	0	1.47
OFC	gene expression	0	0	1.29
OFC	isoform ratio	0	0	1.46
OFC	intron excision ratio	0	0	1.27
OFC	mRNA stability	0	0	1.34
PL	alternative polyA	0	0	1.37
PL	alternative TSS	0	0	1.29
PL	gene expression	1	0	1.37
PL	isoform ratio	1	0	1.42
PL	intron excision ratio	0	0	1.37
PL	mRNA stability	0	0	1.38
pVTA	alternative polyA	0	0	1.27
pVTA	alternative TSS	0	0	1.4
pVTA	gene expression	0	0	1.32
pVTA	isoform ratio	0	0	1.39
pVTA	intron excision ratio	0	0	1.47
pVTA	mRNA stability	0	0	1.38
RMTg	alternative polyA	0	0	1.21
RMTg	alternative TSS	0	0	1.23
RMTg	gene expression	0	0	1.34
RMTg	isoform ratio	0	0	1.31
RMTg	intron excision ratio	0	0	1.32
RMTg	mRNA stability	1	0.2	1.45