Hub : Genes

Wnt11

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Wnt11 0.3 0.14 1.2e-13 0.23 0.23 0.21 0.22 2.5e-12 1.4e-12 1.1e-11 3.4e-12
2 IL gene expression Wnt11 0.37 0.17 1.9e-04 0.09 0.05 0.06 0.05 3.8e-03 2.8e-02 1.7e-02 2.7e-02
3 BLA alternative polyA XM_006229718.4 0.1 0.07 1.4e-03 0.03 0.03 -0 0.02 7.5e-03 7.0e-03 7.1e-01 2.7e-02
4 PL alternative polyA XM_006229718.4 0.09 0.06 2.7e-07 0.06 0.07 0.05 0.06 2.2e-07 8.5e-08 3.1e-06 2.5e-07
5 PL alternative polyA XM_006229718.4 0.08 0.05 3.2e-07 0.06 0.06 0.06 0.06 3.2e-07 1.4e-07 5.6e-07 4.7e-07
6 Brain isoform ratio XM_006229718.4 0.06 0.04 3.3e-04 0.03 0.04 0.03 0.04 6.3e-04 1.4e-04 4.6e-04 1.6e-04
7 pVTA alternative polyA XM_006229718.4 0.32 0.18 8.7e-07 0.06 0.12 0.13 0.12 1.5e-03 6.7e-06 2.9e-06 7.2e-06
8 pVTA alternative polyA NM_080401.1 0.3 0.16 5.8e-07 0.08 0.12 0.13 0.12 2.0e-04 4.7e-06 2.4e-06 6.0e-06
9 pVTA alternative polyA NM_080401.1 0.3 0.17 4.1e-07 0.06 0.13 0.14 0.13 9.7e-04 3.0e-06 1.7e-06 3.9e-06
10 PL gene expression Wnt11 0.15 0.09 1.5e-13 0.1 0.11 0.11 0.11 5.6e-11 2.9e-12 4.4e-12 6.4e-12
11 pVTA isoform ratio XM_006229718.4 0.14 0.1 1.5e-03 0.05 0.02 0.03 0.03 3.0e-03 3.2e-02 2.0e-02 1.4e-02
12 BLA alternative polyA XM_006229718.4 0.1 0.07 1.5e-03 0.04 0.03 0 0.02 5.6e-03 9.4e-03 2.6e-01 2.5e-02
13 NAcc alternative polyA XM_006229718.4 0.13 0.07 9.2e-13 0.12 0.12 0.12 0.12 1.0e-13 1.6e-13 1.2e-13 3.5e-13
14 NAcc alternative polyA XM_006229718.4 0.12 0.06 9.0e-12 0.11 0.11 0.11 0.11 1.0e-12 1.6e-12 1.3e-12 2.9e-12
15 pVTA alternative polyA XM_006229718.4 0.31 0.18 1.2e-06 0.06 0.12 0.13 0.12 1.4e-03 8.0e-06 3.6e-06 8.5e-06
16 Brain alternative polyA XM_006229718.4 0.06 0.04 2.6e-04 0.04 0.04 0.04 0.04 8.3e-05 1.0e-04 9.4e-05 6.8e-05
17 Brain alternative polyA XM_006229718.4 0.06 0.04 2.0e-04 0.04 0.04 0.04 0.05 6.4e-05 8.0e-05 7.5e-05 4.2e-05
18 Adipose alternative TSS XM_006229718.4 0.04 0.03 1.5e-03 0 0.01 0.01 0 3.4e-01 4.1e-02 2.1e-02 2.1e-01
19 Adipose alternative TSS NM_080401.1 0.07 0.06 1.1e-04 0 0.02 0.02 0.01 1.5e-01 5.4e-03 3.6e-03 3.3e-02
20 Adipose alternative TSS XM_006229718.4 0.06 0.05 6.4e-05 0.01 0.02 0.02 0.02 4.4e-02 1.9e-03 1.6e-03 5.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.30.52.4-0.10.00.20.30.30.3-1.41.31.3-0.4-0.3-0.4-0.3-0.3-1.60.60.60.6-0.40.7
Area under the delay curve0.10.10.5-0.10.0-0.2-0.2-0.2-0.20.3-0.1-0.10.00.70.10.10.10.1-0.1-0.1-0.1-0.60.5
BMI with tail0.20.73.70.30.20.80.90.90.70.3-0.6-0.7-0.1-1.6-1.9-1.3-1.30.70.60.60.3-0.3-0.4
BMI without tail1.53.18.4-0.91.31.31.51.51.4-0.6-0.1-0.4-2.2-2.9-2.9-2.5-2.5-0.11.61.62.8-1.71.4
Body weight0.62.66.8-0.81.01.21.41.41.4-0.2-0.2-0.5-1.9-2.3-2.6-2.0-2.00.11.51.52.4-2.31.8
Weight adjusted by age0.40.51.7-0.91.00.10.20.20.20.5-0.7-0.9-1.3-0.6-0.7-0.6-0.60.70.30.31.1-0.50.6
Bone surface0.61.04.5-2.01.7-1.1-1.0-1.0-0.90.1-0.3-0.2-2.10.60.50.80.8-0.1-0.4-0.40.7-0.31.0
Bone volume0.30.52.9-1.41.2-0.5-0.4-0.4-0.3-0.30.00.0-1.7-0.1-0.00.10.1-0.30.00.01.0-0.51.0
Breakpoint value in progressive ratio session0.10.10.60.6-0.70.20.20.20.2-0.20.20.40.7-0.3-0.1-0.1-0.1-0.30.00.0-0.40.1-0.4
Number of licking bursts3.94.56.72.3-2.52.62.52.52.5-2.32.32.11.6-2.2-2.6-2.2-2.2-2.22.02.00.8-1.40.6
Context. condit. distance diff. score2.93.58.8-1.71.8-2.2-2.1-2.1-2.31.3-1.6-1.4-1.21.51.31.61.61.1-2.3-2.3-1.63.0-2.3
Locomotion velocity, session 10.40.42.11.0-1.00.1-0.0-0.0-0.00.8-0.4-0.41.40.60.60.20.20.8-0.2-0.2-0.90.0-0.3
Locomotion distance, session 11.31.64.1-0.20.1-1.0-1.1-1.1-1.22.0-1.8-1.70.51.21.11.11.12.0-1.4-1.4-1.50.9-1.1
Locomotion velocity, session 20.30.31.10.1-0.10.1-0.0-0.00.11.0-0.7-0.80.20.40.7-0.1-0.11.00.10.10.3-1.01.0
Locomotion distance, session 20.30.52.0-0.20.0-0.5-0.5-0.5-0.51.3-1.1-1.20.10.40.70.40.41.4-0.7-0.7-0.3-0.10.1
Locomotion velocity, session 31.01.23.0-0.1-0.2-0.8-0.9-0.9-1.11.6-1.6-1.50.30.40.60.40.41.7-1.3-1.3-1.21.4-1.5
Locomotion distance, session 31.61.83.6-0.30.1-1.3-1.3-1.3-1.51.9-1.7-1.60.31.01.01.11.11.9-1.7-1.7-1.41.4-1.3
Stereotopy head waving bouts, day 30.70.91.50.3-0.70.90.90.91.0-1.01.11.20.0-0.6-0.3-0.9-0.9-1.11.11.11.0-1.21.2
Stereotopy head waving duration, day 30.20.31.1-0.50.6-0.6-0.6-0.6-0.60.3-0.3-0.1-0.40.91.10.40.40.2-0.4-0.4-0.20.40.0
Locomotion velocity, session 70.20.31.20.7-0.50.30.30.30.1-0.20.00.10.7-0.5-0.5-0.6-0.6-0.1-0.3-0.3-0.60.7-1.1
Locomotion distance, session 70.10.10.50.30.10.30.30.30.20.2-0.3-0.40.1-0.5-0.6-0.7-0.70.30.00.0-0.10.0-0.2
Stereotopy head waving bouts, day 71.51.73.8-1.10.5-1.6-1.5-1.5-1.51.3-1.2-1.0-0.51.51.91.71.71.2-1.3-1.3-0.60.8-0.4
Stereotopy head waving duration, day 71.72.03.9-1.71.2-1.7-1.7-1.7-1.61.5-1.4-1.3-1.11.62.01.71.71.4-1.3-1.3-0.20.50.1
Locomotion velocity, session 81.21.42.7-1.61.4-1.6-1.5-1.5-1.40.6-0.6-0.5-1.31.61.51.41.40.3-1.2-1.2-0.20.70.2
Locomotion distance, session 81.92.84.2-1.41.2-1.9-1.9-1.9-1.91.8-1.8-1.7-0.81.51.61.51.51.7-2.1-2.1-1.32.0-1.5
Degree of sensitization distance1.51.52.8-0.20.71.21.21.21.4-1.31.10.8-1.0-1.1-1.1-1.3-1.3-1.21.61.61.7-1.51.5
Degree of sensitization stereotypy3.84.17.1-1.81.2-2.4-2.4-2.4-2.42.2-2.0-1.8-0.82.42.72.72.72.0-2.0-2.0-1.01.1-0.5
Conditioned locomotion0.10.10.30.2-0.3-0.2-0.3-0.3-0.3-0.10.20.30.40.30.50.40.4-0.3-0.4-0.4-0.50.5-0.5
Cocaine response after cond. corrected1.11.32.41.3-1.01.51.41.41.5-0.60.70.51.1-1.0-1.2-1.1-1.1-0.41.31.30.4-1.40.6
Cocaine response after cond. not corrected0.30.31.00.8-0.60.70.60.60.70.20.1-0.00.9-0.1-0.4-0.4-0.40.20.50.5-0.1-1.00.4
Cocaine response before conditioning1.11.32.7-1.00.7-1.5-1.5-1.5-1.41.1-0.8-0.5-0.41.51.61.31.30.7-1.5-1.5-0.80.7-0.1
Saline control response0.91.22.9-1.71.5-1.0-1.0-1.0-0.81.3-1.3-1.3-1.60.81.01.01.01.2-0.5-0.50.4-0.60.9
Bone: connectivity density0.30.41.6-0.70.5-0.6-0.5-0.5-0.5-1.00.91.1-0.70.50.50.40.4-1.3-0.2-0.20.20.10.5
Bone: cortical apparent density1.51.93.00.9-0.81.51.51.51.7-1.61.71.50.4-1.2-1.0-1.3-1.3-1.61.71.71.3-1.51.4
Bone: cortical area0.30.42.4-1.21.2-0.4-0.3-0.3-0.30.3-0.7-0.8-1.5-0.2-0.70.10.10.5-0.2-0.20.6-0.10.1
Bone: cortical porosity1.92.13.5-0.70.6-1.5-1.5-1.5-1.61.9-1.7-1.5-0.01.61.61.41.41.7-1.8-1.8-1.41.2-1.0
Bone: cortical porosity1.41.52.9-0.40.3-1.2-1.3-1.3-1.31.7-1.5-1.30.31.41.41.21.21.6-1.6-1.6-1.20.8-0.7
Bone: cortical thickness0.10.21.10.4-0.30.50.50.50.4-0.40.20.10.2-0.6-1.1-0.4-0.4-0.20.10.1-0.00.1-0.5
Bone: cortical thickness0.40.51.1-0.10.0-0.5-0.5-0.5-0.61.0-1.1-1.00.20.5-0.10.50.51.1-0.8-0.8-1.00.6-1.0
Bone: cortical tissue density1.51.92.90.9-0.91.51.51.51.7-1.61.71.60.4-1.1-0.9-1.2-1.2-1.61.71.71.2-1.51.4
Condit. Reinf. active minus inactive responses0.30.41.0-0.50.70.30.40.40.4-0.1-0.2-0.4-1.0-1.0-1.0-0.8-0.80.10.50.50.9-0.50.4
Condit. Reinf. active-inactive response ratio0.40.53.0-1.31.3-0.10.00.00.0-0.40.0-0.1-1.7-0.5-0.6-0.3-0.3-0.30.40.41.1-0.30.6
Condit. Reinf. active responses0.30.31.10.10.10.60.60.60.6-0.2-0.0-0.2-0.3-1.0-1.0-0.9-0.90.10.60.60.7-0.50.3
Condit. Reinf. inactive responses0.20.20.70.8-0.80.50.40.40.30.3-0.2-0.30.8-0.5-0.4-0.5-0.50.40.10.1-0.1-0.2-0.1
Incentive salience index mean0.30.31.1-0.40.60.30.40.40.3-0.0-0.2-0.4-0.8-1.1-0.9-0.8-0.80.20.40.40.8-0.30.2
Condit. Reinf. lever presses0.00.10.3-0.10.10.10.20.20.1-0.10.00.2-0.3-0.6-0.2-0.4-0.4-0.10.20.20.4-0.10.2
Condit. Reinf. active minus inactive responses4.15.110.3-3.13.2-2.4-2.3-2.3-2.22.7-3.0-3.2-2.72.01.31.91.92.8-1.8-1.80.10.30.2
Condit. Reinf. active-inactive response ratio1.01.02.8-0.90.8-1.0-1.0-1.0-1.01.5-1.6-1.7-0.50.70.30.60.61.6-1.1-1.1-0.50.7-0.8
Condit. Reinf. active responses5.17.016.7-4.04.1-2.8-2.6-2.6-2.43.0-3.3-3.6-3.72.31.52.22.23.0-1.6-1.60.7-0.41.1
Condit. Reinf. inactive responses2.93.610.5-3.23.2-1.8-1.7-1.7-1.31.8-1.9-2.0-3.21.51.31.61.61.6-0.4-0.41.4-1.32.1
Condit. Reinf. lever presses13.818.733.5-5.85.6-5.1-5.0-5.0-4.64.6-4.7-4.6-4.74.54.14.74.74.2-3.5-3.5-0.50.80.6
Condit. Reinf. lever reinforcers received5.98.318.1-4.24.3-3.1-3.0-3.0-2.73.4-3.7-3.9-3.72.51.82.52.53.4-1.9-1.90.4-0.10.9
Conditioned reinforcement - actives2.92.94.5-1.10.9-1.9-2.0-2.0-2.01.7-1.6-1.4-0.42.02.11.91.91.5-2.0-2.0-1.51.5-1.3
Conditioned reinforcement - inactives0.40.51.30.7-0.50.60.50.50.7-0.81.11.10.6-0.10.2-0.0-0.0-1.10.70.70.2-0.80.8
Conditioned locomotion2.63.14.6-0.71.0-1.8-1.9-1.9-1.92.1-1.9-1.90.02.01.92.02.02.0-2.0-2.0-1.81.4-1.3
Patch foraging indifference point 0 sec4.06.511.7-3.43.1-3.1-3.1-3.1-2.92.4-2.6-2.6-2.92.62.42.62.62.2-2.4-2.4-0.61.1-0.3
Patch foraging indifference point AUC0.30.31.0-0.60.70.10.10.10.2-0.60.50.4-0.8-0.3-0.4-0.2-0.2-0.70.40.41.0-0.80.9
Delay disc. indifference point, 0s delay0.50.51.5-0.70.7-0.6-0.6-0.6-0.61.2-1.1-1.2-0.50.80.40.50.51.2-0.5-0.5-0.0-0.30.3
Delay disc. indifference point, 16s delay0.10.10.30.3-0.5-0.1-0.1-0.1-0.1-0.10.20.40.50.40.10.10.1-0.3-0.2-0.2-0.5-0.30.2
Delay disc. indifference point, 2s delay1.11.22.9-1.10.9-1.2-1.2-1.2-1.11.4-1.3-1.4-0.71.71.21.11.11.3-1.0-1.0-0.40.10.0
Delay disc. indifference point, 24s delay1.31.22.50.8-1.11.01.01.01.1-1.31.41.60.6-0.7-1.3-0.9-0.9-1.61.11.10.6-1.21.0
Delay disc. indifference point, 4s delay0.50.52.3-0.40.5-0.2-0.3-0.3-0.21.4-1.3-1.4-0.30.50.20.10.11.5-0.1-0.10.2-0.90.6
Delay disc. indifference point, 8s delay0.30.31.2-0.70.5-0.8-0.7-0.7-0.70.2-0.2-0.2-0.51.10.50.60.60.1-0.6-0.6-0.20.20.0
Indifference point function ln k2.13.04.3-0.90.8-1.8-1.9-1.9-2.02.1-2.0-1.9-0.11.91.91.81.82.1-1.9-1.9-1.71.6-1.3
Indifference point function log k2.13.04.3-0.90.8-1.8-1.9-1.9-2.02.1-2.0-1.9-0.11.91.91.81.82.1-1.9-1.9-1.71.6-1.3
Patch foraging total patch changes 0 sec3.35.39.6-3.12.8-2.9-2.8-2.8-2.72.2-2.3-2.3-2.62.42.22.42.41.9-2.2-2.2-0.60.9-0.2
Patch foraging total patch changes 12 sec0.60.84.5-1.91.8-0.9-0.8-0.8-0.70.1-0.5-0.5-2.10.50.10.40.4-0.0-0.3-0.30.9-0.20.6
Patch foraging total patch changes 18 sec1.01.24.8-2.12.1-1.2-1.1-1.1-1.00.7-0.9-1.0-2.20.60.70.60.60.6-0.6-0.60.9-0.10.7
Patch foraging total patch changes 24 sec0.30.41.4-0.81.0-0.4-0.4-0.4-0.40.9-1.0-1.2-0.80.20.40.20.21.0-0.3-0.30.2-0.10.1
Patch foraging total patch changes 6 sec1.11.73.0-1.61.7-1.7-1.7-1.7-1.60.5-0.8-0.6-1.31.41.01.51.50.2-1.4-1.4-0.61.2-0.6
Patch foraging time to switch 0 sec2.64.09.03.0-2.92.42.32.32.1-1.92.02.02.7-1.9-2.0-1.8-1.8-1.61.61.6-0.2-0.2-0.6
Patch foraging water rate 0 sec2.54.06.3-2.52.4-2.4-2.4-2.4-2.32.2-2.3-2.2-2.01.92.01.91.92.0-1.9-1.9-0.40.6-0.0
Patch foraging water rate 12 sec1.92.94.9-1.71.8-2.0-2.0-2.0-1.92.0-1.9-1.9-1.21.82.21.61.61.9-1.7-1.7-0.70.9-0.3
Patch foraging water rate 18 sec0.30.51.1-1.10.9-0.8-0.8-0.8-0.70.8-0.8-0.7-1.00.60.70.30.30.6-0.6-0.60.10.20.2
Patch foraging water rate 24 sec1.52.13.1-0.60.6-1.5-1.6-1.6-1.71.8-1.7-1.5-0.01.31.41.21.21.7-1.7-1.7-1.51.7-1.5
Patch foraging water rate 6 sec0.91.32.2-0.90.9-1.4-1.4-1.4-1.40.9-0.9-0.9-0.51.21.51.21.20.9-1.4-1.4-0.91.3-0.8
Seeking ratio, delayed vs. immediate footshock1.41.63.41.8-1.81.51.51.51.4-1.11.21.31.6-1.2-1.7-1.3-1.3-1.01.21.20.0-0.60.0
Distance traveled before self-admin0.40.51.00.5-0.70.70.70.70.7-0.90.91.00.3-0.7-0.6-0.4-0.4-1.00.80.80.4-0.40.4
Distance traveled after self-admin0.50.63.01.5-1.40.70.60.60.5-0.40.60.51.7-0.1-0.3-0.2-0.2-0.30.30.3-0.80.3-0.7
Extensor digitorum longus weight0.41.53.3-0.40.41.01.11.21.2-1.41.00.8-1.3-1.5-1.8-1.4-1.4-1.21.31.31.7-1.11.0
Bone: elastic displacement0.91.02.31.5-1.51.11.01.00.9-1.00.91.01.3-0.7-1.2-1.0-1.0-1.00.70.7-0.50.4-0.9
Bone: elastic work0.81.13.81.6-2.01.00.90.90.8-1.11.21.31.6-0.7-1.0-0.6-0.6-1.10.40.4-0.80.3-0.8
Bone: endosteal estimation0.51.05.7-2.11.6-0.7-0.5-0.5-0.40.6-0.8-0.9-2.4-0.1-0.00.20.20.60.10.11.4-0.71.1
Bone: endosteal perimeter0.91.86.9-2.52.2-1.3-1.2-1.2-1.01.0-1.3-1.4-2.60.70.90.90.91.1-0.3-0.31.1-0.61.2
Epididymis fat weight1.33.08.30.6-0.32.02.12.12.0-0.80.50.2-0.5-2.9-2.9-2.4-2.4-0.31.91.92.0-1.60.9
Delta time in closed arm before/after self-admin2.12.04.0-0.10.11.21.31.31.4-1.61.51.3-0.9-1.4-1.3-1.5-1.5-1.61.61.62.0-1.71.7
Delta time in open arm before/after self-admin1.31.33.1-1.81.5-1.4-1.3-1.3-1.20.9-0.9-0.8-1.61.21.21.21.20.7-0.9-0.90.10.10.5
Diff in mean of infusions in LGA sessions2.83.15.12.0-2.02.02.02.01.9-1.71.71.81.6-2.2-2.3-1.9-1.9-1.61.61.60.5-0.80.1
Delay discount exponential model param0.10.10.50.10.10.10.20.20.1-0.20.1-0.0-0.1-0.7-0.1-0.1-0.1-0.00.00.00.10.7-0.6
Extinction: sum of active levers before priming0.30.30.70.4-0.20.60.60.60.60.10.0-0.10.2-0.8-0.2-0.5-0.50.10.60.60.5-0.80.7
Active lever presses in extinction session 65.45.27.6-1.10.8-2.4-2.5-2.5-2.52.5-2.4-2.2-0.12.22.82.52.52.4-2.7-2.7-2.42.4-2.0
Bone: final force0.10.20.5-0.60.6-0.3-0.3-0.3-0.2-0.50.40.4-0.70.1-0.30.50.5-0.70.00.00.2-0.30.5
Bone: final moment0.20.20.9-0.90.7-0.4-0.4-0.4-0.2-0.50.40.4-0.90.2-0.10.60.6-0.70.00.00.3-0.30.6
Food consumed during 24 hour testing period1.92.36.8-1.81.0-1.8-1.8-1.8-1.61.2-0.9-0.8-1.11.92.62.22.20.9-1.2-1.20.0-0.01.0
Glucose0.10.10.80.20.1-0.1-0.2-0.2-0.20.9-0.6-0.40.30.30.30.20.20.7-0.2-0.2-0.3-0.40.3
Heart weight0.70.91.6-1.31.3-1.2-1.2-1.2-1.10.8-0.9-0.7-1.11.00.61.11.10.6-1.1-1.1-0.30.10.3
Delay discount hyperbolic model param0.10.10.70.3-0.10.30.30.30.2-0.50.40.30.1-0.8-0.3-0.2-0.2-0.40.10.10.00.6-0.5
Intermittent access intake day 1-15 change2.32.35.0-1.21.0-1.8-1.8-1.8-1.61.5-1.3-1.3-0.52.22.02.02.01.3-1.4-1.4-1.01.0-0.5
Intermittent access intake escalation2.92.85.8-1.41.3-1.9-2.0-2.0-1.81.8-1.6-1.6-0.62.42.12.12.11.7-1.6-1.6-1.11.0-0.5
Intermittent access intake escalation 20.60.61.5-0.90.6-1.0-1.0-1.0-0.90.7-0.6-0.6-0.71.21.01.01.00.6-0.7-0.7-0.30.5-0.1
Intermitt. access day 1 inactive lever presses0.70.71.80.9-0.70.90.90.90.9-1.11.21.30.7-0.5-0.5-0.8-0.8-1.30.70.70.3-0.40.4
Intermitt. access day 15 inactive lever presses0.10.10.40.4-0.40.0-0.0-0.0-0.0-0.10.20.20.60.20.40.30.3-0.2-0.1-0.1-0.50.3-0.4
Intermitt. access escalation Index0.10.10.7-0.40.1-0.2-0.2-0.2-0.2-0.60.40.7-0.50.2-0.20.10.1-0.9-0.1-0.10.20.10.2
Intermittent access day 1 total infusions0.20.31.2-1.00.9-0.5-0.5-0.5-0.40.1-0.2-0.1-1.10.30.50.50.5-0.0-0.0-0.00.5-0.30.6
Intermittent access day 15 total infusions1.92.14.1-1.51.3-1.7-1.8-1.8-1.61.4-1.2-1.2-0.92.02.01.91.91.2-1.2-1.2-0.70.6-0.1
Intermittent access terminal intake (last 3 days)1.11.22.3-1.41.2-1.3-1.3-1.3-1.20.9-0.9-1.0-1.11.31.51.41.40.8-0.8-0.8-0.30.6-0.2
Intermittent access total infusions0.30.40.9-0.90.8-0.7-0.8-0.8-0.60.5-0.5-0.5-0.80.60.80.80.80.4-0.4-0.40.00.10.1
Intermittent access day 1 locomotion0.10.10.20.1-0.3-0.1-0.2-0.2-0.2-0.20.20.30.20.30.40.40.4-0.3-0.2-0.2-0.40.4-0.3
Intermittent access day 15 total locomotion1.51.62.6-1.01.1-1.4-1.4-1.4-1.41.6-1.5-1.5-0.51.51.51.41.41.5-1.3-1.3-0.80.6-0.4
Intermittent access total locomotion0.40.40.7-0.70.8-0.7-0.7-0.7-0.60.8-0.8-0.9-0.50.70.70.80.80.8-0.5-0.5-0.20.2-0.1
Intermittent access standard deviation0.00.00.1-0.30.1-0.1-0.1-0.10.00.2-0.2-0.3-0.4-0.00.20.00.00.30.20.20.3-0.40.3
Left kidney weight0.41.15.2-1.81.7-0.3-0.2-0.2-0.10.9-1.1-1.3-2.3-0.4-0.4-0.4-0.41.00.20.21.7-1.01.4
Right kidney weight0.30.93.2-1.41.1-0.00.10.10.20.6-0.7-1.0-1.8-0.5-0.5-0.5-0.50.70.50.51.6-1.61.8
Cocaine induced anxiety1.51.73.51.7-1.91.61.61.61.4-1.41.41.31.4-1.5-1.2-1.4-1.4-1.21.11.10.2-0.3-0.1
Post-drug Anxiety0.50.51.10.7-0.80.70.70.70.7-1.01.01.00.5-0.5-0.4-0.5-0.5-1.00.70.70.3-0.40.4
Baseline Anxiety1.61.73.6-1.81.9-1.6-1.6-1.6-1.41.1-1.1-1.0-1.51.71.41.51.50.8-1.0-1.0-0.10.20.4
Tail length1.44.317.1-2.92.80.30.50.60.8-0.1-0.5-1.0-4.1-1.6-1.4-1.4-1.40.31.51.54.0-3.03.5
Length with tail0.82.910.5-1.71.50.91.01.01.3-0.40.1-0.2-2.7-1.4-1.4-1.4-1.4-0.31.61.63.2-2.93.1
Length without tail0.10.31.41.0-1.10.40.20.20.30.10.20.41.20.20.10.00.0-0.10.00.0-0.80.2-0.6
Times rat made contact with spout1.21.42.60.1-0.71.11.11.11.2-1.41.31.1-0.5-1.2-0.8-1.1-1.1-1.31.41.41.6-1.31.5
Lifetime Intake0.60.61.2-1.10.9-1.0-1.0-1.0-0.90.7-0.7-0.7-0.90.91.10.90.90.7-0.6-0.6-0.10.2-0.0
Liver weight, left1.42.37.40.10.31.41.41.41.7-1.31.31.1-0.6-1.0-1.4-1.2-1.2-1.31.81.82.0-2.72.6
Liver weight, right3.45.710.50.8-0.92.62.72.72.9-2.12.01.7-0.2-2.4-2.8-2.3-2.3-2.03.03.02.7-3.22.7
Locomotor activity0.50.91.7-1.31.2-1.0-0.9-0.9-0.91.1-1.2-1.2-1.20.70.90.70.71.2-0.8-0.80.10.30.1
Locomotor testing distance1.32.14.9-2.02.2-1.4-1.3-1.3-1.21.9-2.1-2.2-2.00.80.80.90.92.1-1.2-1.20.30.30.2
Locomotor testing rearing0.40.72.9-1.21.5-0.1-0.1-0.1-0.10.7-0.9-1.0-1.7-0.5-0.2-0.6-0.60.9-0.0-0.01.2-0.60.7
Locomotion in novel chamber1.41.83.0-0.70.8-1.4-1.4-1.4-1.41.7-1.7-1.7-0.21.30.91.41.41.7-1.6-1.6-1.30.7-0.6
Locomotion in novel chamber post-restriction5.26.39.6-1.51.4-2.7-2.7-2.7-2.82.9-2.9-3.1-0.52.52.82.72.73.1-2.9-2.9-2.22.0-1.4
Fecal boli incidents, locomotor time 11.01.11.9-0.60.9-1.1-1.1-1.1-1.11.0-1.0-1.2-0.31.11.41.31.31.0-1.0-1.0-0.91.1-0.6
Change in fecal boli incidents, locomotor task0.80.81.41.2-1.21.01.01.00.9-0.70.91.01.1-0.8-0.7-0.8-0.8-0.80.80.80.1-0.90.4
Time >=10cm from walls, locomotor time 12.52.54.4-1.11.0-1.8-1.8-1.8-1.81.5-1.5-1.4-0.51.62.11.51.51.5-2.0-2.0-1.51.7-1.3
Bouts of movement, locomotor time 10.20.20.9-0.0-0.3-0.2-0.2-0.3-0.20.7-0.7-0.90.20.30.70.00.00.9-0.3-0.3-0.40.2-0.2
Total resting periods, locomotor time 10.20.20.80.3-0.6-0.1-0.2-0.2-0.20.6-0.5-0.70.60.40.90.10.10.8-0.4-0.4-0.70.4-0.5
Rest time, locomotor task time 10.30.42.51.0-1.60.30.20.20.20.4-0.1-0.01.40.50.4-0.1-0.10.4-0.0-0.0-0.8-0.4-0.1
Distance moved, locomotor task time 10.50.53.1-1.21.7-0.1-0.00.00.0-0.3-0.0-0.2-1.7-0.6-0.6-0.2-0.2-0.20.40.41.3-0.20.6
Vertical activity count, locomotor time 10.60.73.5-1.51.9-0.8-0.6-0.6-0.60.1-0.5-0.6-1.8-0.2-0.50.50.50.1-0.3-0.30.80.4-0.0
Time >=10cm from walls, locomotor time 20.80.92.2-0.80.8-0.9-0.9-0.9-0.91.4-1.4-1.4-0.60.91.30.40.41.5-0.9-0.9-0.40.6-0.4
Bouts of movement, locomotor time 20.30.31.2-0.70.4-0.5-0.5-0.5-0.50.8-0.8-0.8-0.60.51.10.20.20.9-0.3-0.30.1-0.10.4
Total resting periods, locomotor time 20.20.20.9-0.40.1-0.3-0.4-0.4-0.30.7-0.6-0.7-0.20.51.00.00.00.8-0.2-0.20.00.00.2
Rest time, locomotor task time 21.61.83.11.6-1.81.51.51.51.5-1.61.61.51.4-1.1-1.2-1.3-1.3-1.51.41.40.3-0.50.3
Distance moved, locomotor task time 21.82.04.2-1.92.0-1.4-1.4-1.4-1.41.9-2.0-2.0-1.81.00.71.11.11.9-1.2-1.20.10.2-0.1
Vertical activity count, locomotor time 20.91.04.1-1.72.0-0.9-0.8-0.8-0.80.8-1.0-1.2-1.90.10.00.40.40.9-0.6-0.60.9-0.10.3
Light reinforcement 11.62.94.01.7-1.52.02.02.02.0-1.92.01.91.2-1.7-2.0-1.5-1.5-1.91.91.90.9-1.40.9
Light reinforcement 20.10.10.40.3-0.1-0.0-0.1-0.10.00.20.00.00.60.6-0.10.70.7-0.0-0.0-0.0-0.3-0.60.4
Bone: marrow area0.40.95.3-1.91.5-0.5-0.4-0.4-0.30.4-0.7-0.7-2.3-0.2-0.10.10.10.40.20.21.4-0.81.1
Bone: maximum diameter1.22.16.7-2.52.3-1.5-1.4-1.4-1.31.3-1.6-1.7-2.61.00.51.21.21.3-1.0-1.00.6-0.10.5
Bone: maximum force0.20.31.1-1.10.7-0.7-0.6-0.6-0.5-0.40.30.4-1.00.40.10.90.9-0.6-0.3-0.30.1-0.00.4
Bone: maximum moment0.20.41.6-1.30.8-0.8-0.6-0.6-0.5-0.40.20.3-1.20.50.20.90.9-0.6-0.3-0.30.3-0.00.5
Mean time between licks in bursts1.92.68.8-2.92.5-1.3-1.2-1.2-0.91.5-1.6-1.7-3.01.11.01.21.21.3-0.2-0.21.7-1.32.0
Mean num. licks in bursts2.63.25.0-2.22.1-2.2-2.1-2.1-2.01.8-1.9-1.9-1.81.72.21.71.71.8-1.5-1.5-0.31.0-0.1
Cd content in liver1.31.53.00.5-0.91.21.31.31.2-1.51.31.30.0-1.5-1.7-1.6-1.6-1.50.90.91.0-0.70.5
Co content in liver0.40.52.0-1.11.1-0.2-0.1-0.1-0.10.4-0.7-0.8-1.4-0.3-0.3-0.4-0.40.6-0.0-0.01.1-0.90.9
Cu content in liver0.30.41.3-0.70.8-0.1-0.1-0.10.00.7-0.7-0.9-0.90.00.2-0.2-0.20.80.10.10.9-1.01.1
Fe content in liver0.00.00.20.10.10.20.20.20.10.1-0.2-0.3-0.0-0.1-0.4-0.1-0.10.20.00.00.1-0.10.2
K content in liver0.60.51.60.2-0.40.60.60.60.6-1.01.11.3-0.0-0.4-0.3-0.6-0.6-1.20.80.80.8-0.60.8
Mg content in liver0.10.10.3-0.40.1-0.4-0.4-0.4-0.40.3-0.2-0.1-0.30.50.50.20.20.1-0.3-0.3-0.10.4-0.2
Mn content in liver0.70.83.61.6-1.80.70.60.60.5-0.60.80.81.9-0.10.0-0.2-0.2-0.60.40.4-1.00.4-0.8
Na content in liver0.80.82.5-0.50.4-1.1-1.1-1.1-1.10.8-0.6-0.40.11.61.41.31.30.6-0.7-0.7-0.80.5-0.1
Rb content in liver0.30.42.1-1.31.0-0.7-0.6-0.6-0.60.2-0.20.2-1.50.40.50.10.1-0.1-0.3-0.30.7-0.20.6
Se content in liver2.83.48.22.8-2.92.22.12.02.0-1.82.01.92.6-1.5-1.4-1.6-1.6-1.71.61.6-0.0-0.80.2
Sr content in liver0.20.20.60.3-0.4-0.2-0.2-0.2-0.30.4-0.5-0.70.50.20.20.30.30.7-0.5-0.5-0.70.6-0.8
Zn content in liver3.74.16.4-2.52.2-2.4-2.3-2.3-2.22.3-2.4-2.4-2.11.91.81.91.92.2-2.0-2.0-0.31.0-0.3
Bone: minimum diameter0.61.14.1-1.30.90.50.60.60.7-0.70.2-0.1-2.0-1.0-1.2-0.9-0.9-0.41.01.02.0-1.31.4
Time in familiar zone, hab. session 10.40.41.10.0-0.20.40.50.50.6-0.80.80.7-0.2-0.1-0.2-0.3-0.3-0.80.70.70.9-0.81.0
Time in novel zone, hab. session 10.10.10.50.2-0.00.30.30.30.30.1-0.3-0.30.0-0.7-0.7-0.6-0.60.30.20.2-0.10.1-0.5
Total zone transitions, hab. session 10.50.81.4-0.20.2-0.9-0.9-0.9-0.90.7-0.6-0.60.31.21.11.11.10.7-1.0-1.0-1.11.1-0.8
Total locomotion distance, hab. session 11.31.83.50.7-0.81.61.71.71.6-1.31.10.90.0-1.9-1.8-1.7-1.7-1.01.51.51.3-1.10.7
Locomotion velocity, hab. session 10.71.02.70.5-0.51.21.31.31.2-0.90.70.6-0.1-1.6-1.5-1.3-1.3-0.71.01.01.0-0.70.4
Time in familiar zone, hab. session 20.50.63.1-1.61.3-0.8-0.6-0.6-0.5-0.3-0.00.0-1.80.30.30.40.4-0.4-0.2-0.21.00.10.6
Time in novel zone, hab. session 20.50.52.01.1-0.90.40.20.20.11.1-0.8-0.81.40.0-0.1-0.1-0.11.2-0.1-0.1-1.10.0-0.8
Total zone transitions, hab. session 22.22.94.0-0.90.6-1.8-1.8-1.8-1.91.9-1.8-1.8-0.11.81.62.02.01.8-2.0-2.0-1.81.6-1.4
Total locomotion distance, hab. session 20.50.72.0-0.1-0.20.80.90.90.9-0.90.60.5-0.5-1.2-1.4-0.8-0.8-0.70.80.81.1-0.90.7
Locomotion velocity, hab. session 20.70.92.3-0.0-0.31.01.11.11.1-0.90.70.5-0.4-1.4-1.5-0.9-0.9-0.81.01.01.2-1.10.8
Novel to familiar place preference ratio0.40.41.4-0.00.2-0.4-0.5-0.5-0.41.1-0.9-1.10.30.60.50.60.61.2-0.5-0.5-0.80.3-0.5
Novelty place preference0.30.41.40.10.0-0.2-0.3-0.3-0.31.1-0.9-1.00.40.40.50.40.41.2-0.4-0.4-0.80.2-0.6
Time in novel zone, NPP test0.50.51.7-0.10.3-0.4-0.5-0.5-0.51.2-1.1-1.20.20.60.60.60.61.3-0.5-0.5-0.80.4-0.6
Total zone transitions, NPP test0.40.61.1-0.0-0.5-0.7-0.7-0.8-0.70.9-0.6-0.60.61.00.81.11.10.8-0.8-0.8-1.00.5-0.5
Total locomotion distance, NPP test1.21.73.91.1-1.51.61.61.61.6-0.90.80.80.8-1.7-2.0-1.3-1.3-0.81.31.30.7-1.30.4
Locomotion velocity, NPP test1.62.24.81.4-1.81.91.91.91.8-1.01.00.91.1-1.9-2.2-1.5-1.5-0.81.51.50.7-1.40.4
Intraocular pressure1.21.73.8-0.40.7-1.3-1.3-1.3-1.41.1-1.1-1.30.11.01.71.31.31.2-1.5-1.5-1.41.9-1.6
Delta distance traveled before/after self-admin0.40.40.80.2-0.0-0.5-0.5-0.5-0.60.7-0.6-0.70.50.90.60.60.60.8-0.7-0.7-0.90.7-0.7
Delta ambulatory time before/after self-admin0.80.81.90.3-0.1-0.7-0.8-0.8-0.80.9-0.7-0.80.91.10.90.90.91.0-1.1-1.1-1.41.2-1.2
Parametrial fat weight1.01.94.20.20.01.31.41.41.5-1.21.00.8-0.6-1.3-1.8-1.4-1.4-1.11.71.71.6-2.01.8
Pavlov. Cond. lever latency0.40.51.81.3-1.20.80.70.70.6-0.40.40.41.3-0.5-0.9-0.5-0.5-0.30.30.3-0.60.3-0.9
Pavlov. Cond. magazine entry latency1.41.84.7-2.22.0-1.5-1.4-1.4-1.41.4-1.6-1.7-2.10.90.91.11.11.4-1.1-1.10.20.50.1
Pavlov. Cond. change in total contacts0.40.41.0-0.90.8-0.7-0.6-0.6-0.61.0-1.0-1.0-0.70.40.60.40.41.0-0.5-0.50.1-0.20.3
Pavlov. Cond. index score1.11.44.4-2.11.9-1.2-1.1-1.1-1.01.1-1.3-1.4-2.10.50.90.70.71.2-0.7-0.70.8-0.10.7
Pavlov. Cond. latency score1.11.44.3-2.11.9-1.3-1.2-1.2-1.11.1-1.3-1.4-2.10.60.90.80.81.1-0.8-0.80.6-0.00.6
Pavlov. Cond. lever contacts0.40.41.8-1.21.0-0.4-0.3-0.3-0.30.4-0.4-0.4-1.4-0.10.4-0.0-0.00.4-0.0-0.01.0-0.71.1
Pavlov. Cond. magazine entry number1.82.35.02.2-2.11.71.61.61.6-1.61.82.02.0-1.0-1.1-1.2-1.2-1.71.31.3-0.1-0.60.0
Pavlov. Cond. intertrial magazine entries1.41.64.12.0-1.81.61.51.51.4-0.60.80.81.8-1.4-1.1-1.6-1.6-0.41.11.10.1-0.80.1
Pavlov. Cond. lever-magazine prob. diff.0.81.03.7-1.91.7-1.0-0.9-0.9-0.90.9-1.0-1.1-1.90.40.80.60.60.9-0.5-0.50.8-0.10.8
Pavlov. Cond. response bias0.30.31.7-1.20.8-0.4-0.3-0.3-0.30.4-0.5-0.5-1.3-0.10.40.10.10.4-0.1-0.10.9-0.40.8
Pavlov. Cond. lever latency14.819.932.15.7-5.25.35.25.24.9-4.94.94.74.4-4.7-4.2-4.8-4.8-4.44.14.11.1-1.60.2
Pavlov. Cond. magazine entry latency5.36.29.1-2.72.8-3.0-3.0-3.0-2.92.5-2.5-2.3-1.92.62.32.82.82.2-2.6-2.6-1.41.7-1.1
Pavlov. Cond. change in total contacts11.816.224.3-4.54.4-4.6-4.5-4.5-4.44.9-4.9-4.9-3.34.13.54.04.04.7-4.0-4.0-1.61.8-1.1
Pavlov. Cond. index score12.716.423.4-4.84.6-4.8-4.7-4.7-4.54.5-4.6-4.4-3.74.13.74.24.24.1-3.9-3.9-1.41.9-0.9
Pavlov. Cond. latency score12.115.021.3-4.54.3-4.6-4.5-4.5-4.44.2-4.3-4.2-3.44.03.64.24.23.9-3.8-3.8-1.51.9-0.9
Pavlov. Cond. lever contacts15.721.534.4-5.95.5-5.5-5.4-5.4-5.15.1-5.1-5.0-4.64.84.44.94.94.6-4.3-4.3-1.11.8-0.4
Pavlov. Cond. magazine entry number7.89.513.63.0-3.13.53.53.53.5-3.63.73.62.0-2.9-2.7-3.1-3.1-3.53.33.31.8-2.21.7
Pavlov. Cond. intertrial magazine entries1.01.34.0-0.30.41.01.01.01.2-0.80.60.2-0.9-1.0-0.9-1.1-1.1-0.51.51.52.0-1.71.9
Pavlov. Cond. lever-magazine prob. diff.11.815.021.5-4.64.5-4.6-4.5-4.5-4.34.3-4.4-4.3-3.53.93.54.14.14.0-3.7-3.7-1.31.8-0.8
Pavlov. Cond. response bias16.121.934.2-5.85.5-5.6-5.4-5.4-5.25.1-5.2-5.0-4.64.84.44.94.94.7-4.4-4.4-1.32.0-0.7
Time in closed arm before self-admin2.12.33.4-0.40.3-1.6-1.6-1.6-1.71.6-1.5-1.40.41.81.61.81.81.4-1.9-1.9-1.81.6-1.4
Time in closed arm after self-admin0.30.31.20.9-0.80.30.20.20.2-0.60.80.81.10.30.50.10.1-0.70.20.2-0.50.10.0
Time in open arm before self-admin2.32.53.71.8-1.61.91.91.91.8-1.51.51.31.3-1.8-1.9-1.7-1.7-1.21.71.70.7-0.90.3
Time in open arm after self-admin0.40.42.1-1.00.7-0.00.10.10.1-0.40.20.3-1.5-0.6-0.6-0.5-0.5-0.40.40.41.2-0.70.8
Bone: periosteal estimation0.51.05.7-2.01.8-0.7-0.6-0.6-0.50.8-1.1-1.2-2.4-0.0-0.30.30.30.9-0.1-0.11.1-0.60.8
Bone: periosteal perimeter0.71.25.9-2.22.0-1.0-0.9-0.9-0.70.6-0.9-1.0-2.40.50.60.70.70.7-0.3-0.31.1-0.51.0
Bone: post-yield work0.40.61.6-1.31.1-0.9-0.8-0.8-0.7-0.60.50.7-1.30.60.70.70.7-0.9-0.4-0.40.3-0.10.7
Progressive ratio test 1 active lever presses0.10.10.40.6-0.60.30.30.30.3-0.40.50.40.7-0.00.00.10.1-0.40.30.3-0.30.0-0.2
Progressive ratio test 1 breakpoint0.20.20.50.5-0.60.40.30.30.4-0.60.70.60.5-0.1-0.00.00.0-0.70.40.4-0.1-0.0-0.1
Progressive ratio test 1 inactive lever presses0.00.10.1-0.40.3-0.2-0.2-0.2-0.2-0.20.20.2-0.40.20.10.30.3-0.3-0.1-0.10.10.10.1
Progressive ratio test 2 active lever presses0.91.02.2-1.21.5-1.0-1.0-1.0-0.91.3-1.3-1.5-1.10.80.90.80.81.4-0.7-0.7-0.00.3-0.1
Progressive ratio test 2 breakpoint0.80.92.2-1.31.5-1.0-1.0-1.0-0.91.1-1.2-1.3-1.20.81.00.80.81.2-0.7-0.70.00.5-0.2
Progressive ratio test 2 inactive lever presses0.40.41.1-0.81.0-0.7-0.7-0.7-0.70.7-0.7-0.7-0.70.60.70.60.60.6-0.6-0.6-0.10.4-0.2
Incentive Sensitization - Responses1.91.94.2-1.92.1-1.4-1.4-1.4-1.31.6-1.7-1.9-1.81.11.11.11.11.7-1.0-1.00.20.4-0.0
Incentive Sensitization - Breakpoint1.92.04.1-1.92.0-1.5-1.5-1.5-1.41.7-1.8-1.9-1.71.21.11.21.21.7-1.1-1.10.00.5-0.1
Sum of active levers in priming session hrs 5-60.10.10.40.3-0.40.20.20.20.20.5-0.4-0.50.3-0.30.2-0.2-0.20.60.10.1-0.1-0.20.1
Progressive ratio0.30.30.7-0.0-0.0-0.5-0.5-0.5-0.60.5-0.5-0.40.30.80.30.70.70.4-0.7-0.7-0.80.6-0.6
Food seeking constrained by brief footshock0.91.12.7-1.61.6-1.0-1.0-1.0-0.81.2-1.2-1.2-1.60.90.70.90.91.1-0.5-0.50.5-0.81.1
Seeking ratio, punishment vs. effort0.50.62.4-1.21.4-0.2-0.2-0.2-0.10.3-0.4-0.5-1.5-0.10.2-0.1-0.10.30.40.41.2-1.11.4
Retroperitoneal fat weight5.116.933.61.8-1.54.74.84.84.8-3.52.92.5-0.4-5.5-5.8-5.0-5.0-2.94.74.74.3-4.33.0
Reaction time number correct0.40.61.50.3-0.7-0.7-0.7-0.7-0.80.3-0.10.10.81.11.00.80.80.1-1.0-1.0-1.21.0-0.8
Reaction time mean minus median0.60.82.9-1.51.7-0.9-0.8-0.8-0.70.9-0.9-1.0-1.60.50.80.80.80.9-0.4-0.40.4-0.10.6
Reaction time mean minus median AUC1.01.33.0-1.51.7-1.2-1.2-1.2-1.11.2-1.1-1.2-1.31.11.41.41.41.1-0.8-0.8-0.00.20.3
Reaction time num false alarms2.43.25.31.5-1.92.02.02.02.0-2.12.02.01.0-2.0-2.3-1.7-1.7-2.01.91.91.1-1.10.5
Reaction time num false alarms AUC1.41.93.61.4-1.91.51.51.51.5-1.51.51.61.1-1.4-1.6-1.2-1.2-1.51.41.40.7-0.80.2
Reaction time trials correct on left0.40.61.50.3-0.7-0.7-0.7-0.7-0.80.3-0.10.10.81.11.00.80.80.1-1.0-1.0-1.21.0-0.8
Reaction time trials on left0.50.61.60.3-0.7-0.7-0.8-0.8-0.80.3-0.20.10.81.21.00.90.90.1-1.0-1.0-1.31.0-0.8
Reaction time mean0.40.51.70.20.10.80.80.80.9-0.50.60.4-0.1-0.6-0.3-0.5-0.5-0.41.21.20.7-1.31.0
Reaction time mean AUC0.60.71.90.6-0.31.01.01.01.1-0.60.80.70.3-0.7-0.3-0.6-0.6-0.71.31.30.6-1.41.0
Median of all reaction times0.60.91.90.7-0.51.11.11.01.2-0.81.00.90.4-0.7-0.4-0.6-0.6-0.81.41.40.6-1.40.9
Reaction time omissions0.10.10.40.1-0.00.40.40.30.40.1-0.0-0.1-0.0-0.2-0.4-0.1-0.10.00.60.60.1-0.30.2
Reaction time false alarm rate1.72.43.91.2-1.41.81.81.81.8-1.61.51.40.7-1.9-2.0-1.6-1.6-1.41.81.81.1-1.20.5
Reaction time premature initiation rate0.91.17.8-2.12.3-0.4-0.3-0.3-0.20.2-0.7-0.9-2.8-0.3-0.6-0.3-0.30.30.20.21.4-0.30.7
Reaction time premature initiations0.60.84.4-1.81.8-0.9-0.8-0.8-0.80.5-0.9-0.9-2.10.40.10.30.30.5-0.5-0.50.50.40.1
Std. dev. reaction times0.30.52.1-1.01.4-0.0-0.0-0.00.10.4-0.5-0.7-1.4-0.3-0.0-0.1-0.10.50.40.41.0-0.80.9
Reaction time trials completed0.50.61.60.3-0.7-0.7-0.8-0.8-0.80.3-0.20.10.81.21.00.90.90.1-1.0-1.0-1.31.0-0.8
Reaction time trials AUC0.30.51.20.2-0.6-0.6-0.7-0.7-0.70.4-0.20.00.71.10.90.80.80.2-0.9-0.9-1.10.8-0.6
Run reversals in cocaine runway, females3.73.68.5-0.50.61.51.71.71.8-1.91.61.4-1.6-2.1-2.2-2.1-2.1-1.92.22.22.9-2.22.3
Run reversals in cocaine runway, males0.20.21.1-0.1-0.1-0.1-0.1-0.10.0-0.60.80.9-0.00.21.00.30.3-0.90.20.20.10.10.4
Latency to leave start box in cocaine runway1.41.63.31.5-1.81.51.51.51.4-1.31.51.51.3-1.3-0.6-1.1-1.1-1.21.21.20.3-0.50.1
Latency to leave start box in cocaine runway, F1.31.42.21.1-1.51.41.51.51.4-1.21.21.10.8-1.4-1.2-1.1-1.1-1.01.31.30.7-0.90.5
Latency to leave start box in cocaine runway, M0.20.20.60.6-0.70.10.10.10.0-0.50.60.70.80.20.60.10.1-0.5-0.1-0.1-0.60.7-0.6
Std. dev. time between licks in bursts0.60.72.9-1.41.2-0.1-0.0-0.00.10.2-0.3-0.4-1.7-0.2-0.2-0.2-0.20.20.50.51.7-1.31.6
Total sessions with >9 infusions2.22.43.6-1.61.5-1.9-1.9-1.9-1.91.5-1.5-1.4-1.11.71.51.81.81.3-1.7-1.7-0.81.0-0.7
Short access day 1 total inactive lever presses0.20.20.70.6-0.10.50.40.40.5-0.20.40.40.50.00.2-0.2-0.2-0.30.50.50.2-0.80.7
Short access day 10 total inactive lever presses0.10.10.50.5-0.50.30.20.30.2-0.40.50.70.5-0.2-0.1-0.2-0.2-0.60.10.1-0.30.2-0.2
Short access day 1 total infusions1.51.62.9-1.71.6-1.5-1.5-1.5-1.31.3-1.3-1.4-1.51.51.51.31.31.3-1.0-1.00.00.00.5
Short access day 10 total infusions0.30.30.9-0.90.8-0.6-0.6-0.6-0.50.5-0.6-0.7-1.00.40.50.30.30.5-0.3-0.30.20.10.0
Short access total infusions0.30.31.1-1.00.8-0.7-0.7-0.7-0.60.3-0.4-0.4-1.00.70.60.60.60.3-0.3-0.30.30.00.2
Short access day 1 locomotion3.74.05.8-1.11.0-2.2-2.2-2.2-2.22.0-1.9-1.9-0.22.32.42.42.41.9-2.3-2.3-2.01.9-1.6
Short access day 10 total locomotion0.20.30.5-0.40.4-0.5-0.5-0.5-0.50.7-0.7-0.7-0.30.40.30.50.50.7-0.6-0.6-0.30.4-0.4
Short access total locomotion0.20.20.5-0.20.0-0.5-0.6-0.6-0.50.3-0.3-0.30.00.70.50.70.70.2-0.6-0.6-0.60.6-0.5
One hour access (0.3 mA shock)1.51.73.1-1.51.5-1.4-1.4-1.4-1.41.6-1.7-1.8-1.31.01.21.01.01.7-1.3-1.3-0.40.9-0.6
Compulsive drug intake0.60.61.90.3-0.1-0.4-0.4-0.4-0.51.2-1.2-1.20.5-0.0-0.10.20.21.4-0.9-0.9-1.01.0-1.2
One hour access (shock baseline)0.91.12.9-1.31.2-1.2-1.2-1.2-1.00.9-0.7-0.9-1.21.41.71.11.10.8-0.8-0.8-0.10.40.1
Social response proportion1.01.02.10.6-1.01.11.11.11.1-1.21.31.40.4-0.8-0.6-0.9-0.9-1.41.11.10.7-1.10.9
Social responses1.62.03.00.5-0.71.51.61.61.6-1.61.41.3-0.1-1.7-1.4-1.7-1.7-1.51.61.61.6-1.41.2
Social time2.02.67.32.6-2.71.91.71.71.6-1.41.71.82.6-1.4-1.0-1.2-1.2-1.41.11.1-0.5-0.3-0.6
Soleus weight1.03.16.9-0.60.21.41.61.61.7-1.81.51.4-1.6-2.0-1.8-1.8-1.8-1.82.02.02.6-2.12.2
Bone: stiffness0.30.51.7-0.50.30.10.20.20.4-1.11.11.0-0.60.1-0.40.40.4-1.30.60.60.7-1.01.2
Tibialis anterior weight0.10.21.4-0.90.7-0.10.00.00.1-0.30.1-0.0-1.2-0.3-0.3-0.2-0.2-0.30.20.20.8-0.30.5
Time to tail flick, vehicle, before self-admin0.60.61.80.2-0.30.60.70.70.6-1.00.80.9-0.2-0.8-1.3-1.0-1.0-1.10.60.60.8-0.40.6
Time to tail flick, vehicle, after self-admin1.81.92.8-1.41.4-1.7-1.7-1.7-1.61.2-1.2-1.1-1.01.71.51.61.61.1-1.5-1.5-0.91.1-0.6
Time to tail flick, test, before self-admin0.10.10.5-0.50.4-0.00.00.00.1-0.20.10.2-0.7-0.2-0.5-0.2-0.2-0.40.20.20.6-0.50.6
Time to tail flick, test, after self-admin0.20.20.6-0.40.50.20.20.20.20.4-0.5-0.6-0.7-0.1-0.2-0.5-0.50.60.40.40.7-0.80.7
Delta time to tail flick, vehicle, before/after SA4.04.06.9-1.31.3-2.1-2.2-2.2-2.12.1-1.9-2.0-0.52.42.62.32.32.1-2.1-2.1-1.81.7-1.4
Delta time to tail flick, test, before/after SA0.10.10.60.6-0.60.30.20.20.20.2-0.1-0.20.70.10.4-0.2-0.20.40.20.2-0.30.1-0.3
Tibia length1.95.47.7-1.51.5-2.6-2.6-2.6-2.82.7-2.7-2.4-0.62.11.92.32.32.5-2.7-2.7-2.12.5-2.1
Ambulatory time before self-admin0.40.41.00.8-1.00.60.60.60.6-0.60.80.80.9-0.6-0.4-0.3-0.3-0.70.50.5-0.1-0.1-0.1
Ambulatory time after self-admin0.60.74.41.7-1.30.50.30.30.30.00.30.32.10.30.20.00.00.1-0.1-0.1-1.30.6-1.0
Bone: tissue strength0.80.82.70.6-0.5-0.6-0.6-0.6-0.7-0.00.10.21.10.50.60.90.9-0.2-1.0-1.0-1.61.7-1.6
Total heroin consumption0.10.10.4-0.30.0-0.4-0.4-0.4-0.40.3-0.3-0.3-0.00.50.60.50.50.2-0.4-0.4-0.30.6-0.3
Bone: trabecular number0.91.55.30.9-1.00.90.90.90.9-2.22.02.20.5-1.0-1.1-0.9-0.9-2.30.90.90.2-0.10.1
Bone: trabecular spacing1.72.25.6-0.71.1-1.3-1.4-1.4-1.42.2-2.0-2.2-0.21.41.71.31.32.4-1.5-1.5-1.10.9-0.7
Bone: trabecular thickness0.81.01.70.1-0.30.91.01.01.0-1.21.00.8-0.5-1.2-1.2-1.0-1.0-1.11.01.01.2-1.31.1
Bone: trabecular tissue density1.21.73.40.6-0.51.61.61.61.7-1.11.10.80.1-1.2-1.4-1.2-1.2-0.91.81.81.4-1.81.5
Water consumed over 24 hours1.11.32.11.2-1.51.21.31.31.2-1.31.41.40.8-1.1-0.9-1.1-1.1-1.31.21.20.7-0.80.7
Number of responses in last shaping day0.30.31.0-0.50.50.30.40.40.3-0.50.30.2-1.0-0.8-0.8-0.7-0.7-0.40.50.51.0-0.20.3