Mogat2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Mogat2 0.41 0.15 0.0e+00 0.36 0.38 0.37 0.37 2.6e-41 1.9e-43 3.6e-42 3.0e-42
2 BLA gene expression Mogat2 0.25 0.11 1.3e-13 0.2 0.22 0.21 0.2 8.7e-11 3.8e-12 2.4e-11 8.1e-11
3 Liver gene expression Mogat2 0.18 0.09 5.9e-15 0.11 0.11 0.1 0.1 4.7e-12 5.6e-12 2.7e-11 1.3e-11
4 IL gene expression Mogat2 0.33 0.16 3.5e-04 0.08 0.08 0.07 0.07 5.0e-03 5.3e-03 1.0e-02 1.0e-02
5 NAcc gene expression Mogat2 0.25 0.11 0.0e+00 0.28 0.27 0.27 0.28 8.5e-33 4.1e-31 5.9e-31 1.8e-32
6 Brain gene expression Mogat2 0.04 0.03 9.6e-04 0.03 0.02 0.02 0.02 6.5e-04 1.0e-02 3.2e-03 9.0e-03
7 pVTA gene expression Mogat2 0.32 0.13 1.9e-12 0.28 0.25 0.27 0.26 1.0e-12 2.1e-11 5.9e-12 1.1e-11
8 OFC gene expression Mogat2 0.19 0.13 6.1e-03 0 0.02 -0.01 0 2.8e-01 1.1e-01 7.1e-01 2.4e-01
9 pVTA intron excision ratio chr1_153522681_153524762 0.26 0.12 4.5e-07 0.11 0.12 0.12 0.13 1.5e-05 5.1e-06 5.7e-06 4.4e-06
10 Adipose gene expression Mogat2 0.24 0.1 0.0e+00 0.22 0.23 0.22 0.23 1.2e-23 2.2e-25 3.2e-24 5.9e-25

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.21.40.30.10.10.10.1-0.10.1-0.10.51.2
Area under the delay curve0.00.00.2-0.2-0.10.1-0.1-0.0-0.10.2-0.1-0.2-0.4
BMI with tail0.00.00.20.0-0.00.0-0.1-0.2-0.1-0.2-0.20.40.1
BMI without tail1.42.87.8-1.1-1.51.31.31.41.41.4-2.21.72.8
Body weight0.41.74.4-1.0-1.21.11.00.80.90.8-1.91.62.1
Weight adjusted by age1.11.32.0-1.0-1.21.11.11.21.11.2-1.40.31.4
Bone surface1.83.15.5-1.6-1.72.02.01.81.61.8-1.8-0.52.4
Bone volume1.11.95.0-1.0-1.21.41.41.41.21.4-1.40.02.2
Breakpoint value in progressive ratio session0.40.40.60.60.6-0.6-0.7-0.8-0.6-0.70.70.1-0.7
Number of licking bursts4.14.85.92.42.3-2.2-2.2-2.4-2.3-2.41.82.4-1.1
Context. condit. distance diff. score2.73.25.4-2.0-1.72.12.11.71.91.7-1.3-2.30.3
Locomotion velocity, session 10.91.01.71.01.0-1.2-1.2-0.9-0.6-0.81.3-0.3-1.3
Locomotion distance, session 10.30.32.0-0.4-0.30.20.20.10.40.20.2-1.4-0.9
Locomotion velocity, session 20.00.00.10.10.0-0.4-0.40.0-0.00.10.10.2-0.1
Locomotion distance, session 20.10.10.3-0.3-0.30.10.10.40.40.4-0.1-0.6-0.0
Locomotion velocity, session 30.30.31.7-0.5-0.30.40.30.30.50.30.1-1.3-0.6
Locomotion distance, session 30.50.62.9-0.7-0.50.50.50.60.80.60.0-1.7-0.7
Stereotopy head waving bouts, day 30.20.21.00.40.3-0.5-0.5-0.4-0.4-0.40.11.00.3
Stereotopy head waving duration, day 30.20.20.3-0.4-0.40.40.50.50.50.5-0.3-0.50.3
Locomotion velocity, session 70.30.40.70.50.6-0.5-0.6-0.7-0.7-0.70.7-0.1-0.8
Locomotion distance, session 70.00.00.10.10.2-0.1-0.2-0.3-0.1-0.30.10.2-0.2
Stereotopy head waving bouts, day 71.01.22.1-1.2-1.21.01.01.31.11.1-0.8-1.50.2
Stereotopy head waving duration, day 71.92.33.2-1.7-1.71.41.51.81.61.6-1.3-1.40.9
Locomotion velocity, session 81.51.82.5-1.4-1.31.51.61.41.31.3-1.2-1.11.0
Locomotion distance, session 81.52.24.0-1.7-1.51.61.61.51.61.5-1.1-2.00.1
Degree of sensitization distance0.50.52.60.0-0.10.20.1-0.1-0.1-0.0-0.71.61.2
Degree of sensitization stereotypy2.62.95.0-1.9-1.81.51.62.01.81.8-1.2-2.20.3
Conditioned locomotion0.10.10.20.20.3-0.2-0.3-0.2-0.2-0.20.4-0.3-0.5
Cocaine response after cond. corrected1.82.03.11.41.4-1.4-1.3-1.8-1.5-1.81.11.4-1.1
Cocaine response after cond. not corrected0.91.01.80.90.9-1.0-0.8-1.3-1.1-1.30.90.6-1.1
Cocaine response before conditioning0.70.82.0-0.9-0.90.90.91.01.01.0-0.5-1.40.4
Saline control response1.72.22.9-1.6-1.71.61.51.51.51.5-1.7-0.51.4
Bone: connectivity density0.20.41.4-0.3-0.40.70.60.60.50.6-0.4-0.31.2
Bone: cortical apparent density0.81.03.11.21.0-1.1-1.0-0.9-0.7-0.90.61.80.3
Bone: cortical area1.01.52.4-1.1-1.21.51.51.11.11.1-1.4-0.11.6
Bone: cortical porosity0.60.62.6-0.8-0.60.60.70.70.60.6-0.2-1.6-0.6
Bone: cortical porosity0.30.41.9-0.5-0.40.30.30.40.40.50.1-1.4-0.7
Bone: cortical thickness0.10.10.20.40.4-0.2-0.2-0.4-0.3-0.50.30.40.1
Bone: cortical thickness0.10.10.4-0.2-0.10.30.1-0.1-0.2-0.10.1-0.6-0.4
Bone: cortical tissue density0.81.13.11.21.1-1.1-1.0-1.0-0.8-0.90.61.70.2
Condit. Reinf. active minus inactive responses0.50.61.7-0.6-0.70.70.70.70.70.7-1.00.41.3
Condit. Reinf. active-inactive response ratio1.71.93.8-1.2-1.31.41.41.31.31.4-1.60.32.0
Condit. Reinf. active responses0.10.10.4-0.0-0.20.10.00.10.20.2-0.30.50.7
Condit. Reinf. inactive responses0.30.40.60.60.6-0.8-0.8-0.6-0.5-0.60.70.1-0.7
Incentive salience index mean0.40.51.3-0.6-0.70.60.50.70.80.7-0.90.31.1
Condit. Reinf. lever presses0.10.20.3-0.3-0.40.30.00.50.50.5-0.40.10.6
Condit. Reinf. active minus inactive responses6.58.110.4-3.2-3.23.03.12.83.22.9-2.9-1.91.8
Condit. Reinf. active-inactive response ratio0.90.91.4-1.2-1.11.01.00.81.10.9-0.8-1.10.0
Condit. Reinf. active responses9.513.216.5-4.0-4.13.93.93.63.83.7-3.9-1.92.9
Condit. Reinf. inactive responses6.68.110.0-2.9-3.12.93.03.02.93.0-3.2-0.83.0
Condit. Reinf. lever presses18.525.131.4-5.6-5.55.55.55.25.25.2-4.9-4.03.1
Condit. Reinf. lever reinforcers received10.314.418.1-4.2-4.34.14.13.84.13.9-4.0-2.32.8
Conditioned reinforcement - actives1.21.23.6-1.2-1.11.10.91.11.01.0-0.5-1.9-0.3
Conditioned reinforcement - inactives0.60.71.10.90.8-0.9-0.9-1.0-0.9-0.90.70.6-0.7
Conditioned locomotion0.50.63.4-0.8-0.60.60.60.60.60.6-0.0-1.8-0.6
Patch foraging indifference point 0 sec6.09.711.8-3.4-3.33.43.33.33.23.3-3.0-2.61.9
Patch foraging indifference point AUC0.30.30.6-0.5-0.60.60.60.30.30.3-0.80.50.7
Delay disc. indifference point, 0s delay0.50.61.1-0.9-0.80.70.50.81.01.0-0.7-0.60.3
Delay disc. indifference point, 16s delay0.20.20.60.30.4-0.4-0.5-0.5-0.7-0.40.5-0.2-0.8
Delay disc. indifference point, 2s delay1.01.11.8-1.3-1.10.90.80.91.31.3-0.9-1.1-0.5
Delay disc. indifference point, 24s delay0.90.91.61.11.0-0.8-0.8-1.1-1.2-1.20.71.00.1
Delay disc. indifference point, 4s delay0.40.41.4-0.7-0.70.30.20.51.11.2-0.6-0.2-0.2
Delay disc. indifference point, 8s delay0.30.30.5-0.7-0.60.70.50.50.40.6-0.5-0.60.0
Indifference point function ln k0.81.14.2-1.0-0.80.90.81.11.01.1-0.3-2.1-0.4
Indifference point function log k0.81.14.2-1.0-0.80.90.81.11.01.1-0.3-2.1-0.4
Patch foraging total patch changes 0 sec4.87.79.7-3.1-3.03.13.02.92.82.9-2.7-2.31.6
Patch foraging total patch changes 12 sec2.63.44.5-1.9-2.02.12.01.81.71.8-2.1-0.31.8
Patch foraging total patch changes 18 sec3.03.94.8-2.0-2.12.01.92.22.12.1-2.2-0.62.0
Patch foraging total patch changes 24 sec0.40.50.9-1.0-0.90.80.80.70.70.6-0.9-0.20.3
Patch foraging total patch changes 6 sec1.42.03.3-1.6-1.51.81.81.31.31.3-1.2-1.40.7
Patch foraging time to switch 0 sec4.67.18.72.92.9-2.9-3.0-2.8-2.6-2.82.71.7-2.0
Patch foraging water rate 0 sec3.25.16.5-2.5-2.52.52.52.32.22.3-2.1-2.01.2
Patch foraging water rate 12 sec1.62.43.3-1.7-1.61.61.61.61.61.7-1.2-1.80.7
Patch foraging water rate 18 sec0.91.11.6-1.1-1.11.21.31.11.11.1-1.0-0.70.9
Patch foraging water rate 24 sec0.50.83.7-0.8-0.70.70.80.80.60.7-0.1-1.9-0.4
Patch foraging water rate 6 sec0.50.81.9-0.9-0.80.91.00.90.71.0-0.5-1.40.2
Seeking ratio, delayed vs. immediate footshock2.22.53.51.91.7-1.7-1.6-1.8-1.5-1.81.71.2-0.7
Distance traveled before self-admin0.30.30.60.70.6-0.5-0.7-0.6-0.5-0.50.40.8-0.1
Distance traveled after self-admin2.22.43.21.61.7-1.6-1.7-1.7-1.7-1.71.80.4-1.3
Extensor digitorum longus weight0.20.72.8-0.3-0.50.60.50.50.20.5-1.11.31.7
Bone: elastic displacement1.92.13.21.61.6-1.4-1.2-1.7-1.8-1.71.50.7-1.0
Bone: elastic work2.02.63.81.71.8-1.5-1.6-1.8-1.9-1.81.80.6-1.2
Bone: endosteal estimation1.94.15.8-2.0-2.12.12.12.01.82.1-2.4-0.02.4
Bone: endosteal perimeter2.65.46.9-2.4-2.52.52.52.52.22.5-2.6-0.52.4
Epididymis fat weight0.30.63.90.40.1-0.3-0.3-0.6-0.6-0.5-0.52.00.9
Delta time in closed arm before/after self-admin0.50.52.80.0-0.10.10.00.20.10.2-0.71.71.2
Delta time in open arm before/after self-admin2.72.63.6-1.7-1.71.71.91.61.61.5-1.6-1.01.4
Diff in mean of infusions in LGA sessions2.93.24.11.91.9-1.8-1.9-2.0-1.9-1.91.61.7-1.1
Delay discount exponential model param0.00.00.20.1-0.00.00.20.10.1-0.2-0.00.10.5
Extinction: sum of active levers before priming0.20.20.40.40.4-0.4-0.5-0.6-0.4-0.60.30.5-0.1
Active lever presses in extinction session 61.61.66.7-1.3-1.01.11.01.11.01.1-0.3-2.6-0.8
Bone: final force0.10.20.5-0.3-0.30.60.60.20.30.3-0.40.00.7
Bone: final moment0.30.41.0-0.5-0.60.80.90.50.60.5-0.7-0.01.0
Food consumed during 24 hour testing period1.92.33.7-1.5-1.61.31.21.81.91.8-1.2-1.41.4
Glucose0.10.10.30.20.2-0.3-0.2-0.2-0.0-0.30.4-0.3-0.5
Heart weight0.91.32.0-1.2-1.21.41.41.11.01.1-1.0-1.00.9
Delay discount hyperbolic model param0.10.10.20.30.2-0.2-0.0-0.1-0.2-0.50.20.20.4
Intermittent access intake day 1-15 change0.90.92.6-1.1-0.90.91.01.00.90.9-0.6-1.6-0.1
Intermittent access intake escalation1.21.23.3-1.2-1.01.11.11.11.11.1-0.7-1.8-0.0
Intermittent access intake escalation 20.60.60.8-0.9-0.80.80.90.80.80.8-0.7-0.90.3
Intermitt. access day 1 inactive lever presses0.60.71.10.90.8-0.8-0.8-1.1-0.9-0.90.70.7-0.6
Intermitt. access day 15 inactive lever presses0.20.20.30.40.4-0.5-0.5-0.5-0.5-0.50.6-0.3-0.4
Intermitt. access escalation Index0.20.20.5-0.3-0.40.50.40.30.20.2-0.4-0.20.7
Intermittent access day 1 total infusions0.70.81.4-0.8-0.90.90.90.90.90.9-1.00.01.2
Intermittent access day 15 total infusions1.11.31.9-1.2-1.11.21.21.21.11.1-0.9-1.40.5
Intermittent access terminal intake (last 3 days)1.11.21.4-1.2-1.11.11.21.21.11.1-1.0-1.00.7
Intermittent access total infusions0.50.60.7-0.8-0.80.80.80.80.80.8-0.7-0.40.7
Intermittent access day 1 locomotion0.00.00.10.20.2-0.1-0.1-0.1-0.1-0.10.2-0.1-0.1
Intermittent access day 15 total locomotion0.70.81.9-0.9-0.80.80.90.90.90.9-0.5-1.40.2
Intermittent access total locomotion0.30.30.4-0.6-0.60.60.60.60.60.6-0.5-0.50.4
Intermittent access standard deviation0.10.10.1-0.3-0.30.20.40.20.20.2-0.40.00.4
Left kidney weight1.33.75.6-1.9-2.11.91.82.02.02.0-2.40.12.2
Right kidney weight0.82.14.0-1.3-1.61.31.31.31.51.4-1.90.32.0
Cocaine induced anxiety1.92.23.11.61.6-1.5-1.8-1.5-1.5-1.51.41.3-0.9
Post-drug Anxiety0.40.50.70.70.7-0.7-0.8-0.7-0.7-0.70.50.7-0.4
Baseline Anxiety2.02.12.8-1.6-1.51.51.71.61.51.5-1.4-1.20.9
Tail length3.410.219.5-2.8-3.22.93.03.03.03.1-4.11.64.4
Length with tail1.03.89.3-1.5-1.91.61.61.61.51.7-2.61.83.1
Length without tail0.61.22.10.91.0-1.0-1.1-1.2-1.3-1.21.1-0.0-1.4
Times rat made contact with spout0.30.42.00.30.0-0.1-0.20.10.10.0-0.41.41.2
Lifetime Intake0.70.81.0-1.0-0.90.91.01.00.90.9-0.8-0.60.6
Liver weight, left0.40.63.30.50.2-0.4-0.4-0.4-0.3-0.4-0.41.81.1
Liver weight, right1.11.88.81.10.8-1.0-1.1-1.2-1.1-1.2-0.13.01.1
Locomotor activity1.01.62.3-1.1-1.31.31.41.41.41.4-1.2-0.71.5
Locomotor testing distance2.64.35.2-2.0-2.22.22.22.32.32.3-2.1-0.92.0
Locomotor testing rearing1.52.33.3-1.4-1.61.51.51.61.61.6-1.80.31.8
Locomotion in novel chamber0.50.62.6-0.7-0.60.70.70.80.60.7-0.2-1.60.1
Locomotion in novel chamber post-restriction2.02.49.0-1.7-1.31.41.41.41.21.1-0.7-3.0-0.8
Fecal boli incidents, locomotor time 10.30.31.5-0.5-0.60.50.60.40.60.4-0.2-1.20.2
Change in fecal boli incidents, locomotor task1.41.41.81.21.2-1.3-1.3-1.3-1.0-1.21.10.8-1.1
Time >=10cm from walls, locomotor time 11.11.14.0-1.2-1.01.11.00.80.90.8-0.6-2.0-0.4
Bouts of movement, locomotor time 10.00.00.2-0.1-0.0-0.0-0.1-0.10.4-0.10.1-0.4-0.3
Total resting periods, locomotor time 10.20.20.30.30.4-0.4-0.4-0.5-0.1-0.50.5-0.5-0.6
Rest time, locomotor task time 11.01.11.71.01.0-1.2-1.2-1.2-0.9-0.91.2-0.1-1.3
Distance moved, locomotor task time 11.61.83.0-1.1-1.21.41.41.41.31.5-1.60.41.7
Vertical activity count, locomotor time 12.22.32.9-1.5-1.51.71.71.71.61.6-1.7-0.21.4
Time >=10cm from walls, locomotor time 20.60.71.0-1.0-1.00.80.80.70.90.9-0.7-0.90.1
Bouts of movement, locomotor time 20.50.51.0-0.8-0.80.60.60.81.01.0-0.7-0.5-0.0
Total resting periods, locomotor time 20.20.30.6-0.6-0.40.30.30.50.80.8-0.4-0.4-0.4
Rest time, locomotor task time 22.32.63.51.91.8-1.6-1.7-1.8-1.7-1.61.61.4-0.9
Distance moved, locomotor task time 23.13.64.6-2.1-2.11.92.02.02.12.0-2.0-1.11.3
Vertical activity count, locomotor time 22.73.04.0-1.9-1.91.71.82.01.81.7-2.0-0.41.6
Light reinforcement 11.52.73.51.91.7-1.7-1.7-1.7-1.7-1.71.31.9-0.5
Light reinforcement 20.20.20.30.50.5-0.6-0.5-0.4-0.3-0.50.6-0.0-0.3
Bone: marrow area1.63.65.2-1.8-2.02.02.01.91.71.9-2.30.12.3
Bone: maximum diameter3.05.47.1-2.4-2.52.62.72.42.22.4-2.6-0.92.2
Bone: maximum force0.40.61.1-0.7-0.71.01.00.70.60.7-0.8-0.21.0
Bone: maximum moment0.61.01.8-0.9-1.01.21.31.00.80.9-1.1-0.31.3
Mean time between licks in bursts5.57.710.9-2.8-3.02.72.72.93.32.9-3.2-0.42.8
Mean num. licks in bursts4.04.86.0-2.3-2.32.22.22.52.42.4-1.9-1.91.6
Cd content in liver0.30.31.50.50.4-0.4-0.5-0.5-0.4-0.50.01.20.4
Co content in liver1.61.92.8-1.3-1.41.11.31.51.71.6-1.60.11.5
Cu content in liver0.60.71.1-0.9-1.00.70.50.91.01.0-1.00.20.7
Fe content in liver0.00.00.10.10.10.0-0.0-0.20.1-0.20.00.2-0.2
K content in liver0.10.10.50.20.1-0.2-0.30.0-0.2-0.1-0.00.70.3
Mg content in liver0.20.20.3-0.5-0.50.50.40.50.40.4-0.4-0.30.0
Mn content in liver2.42.73.61.71.7-1.7-1.6-1.8-1.8-1.71.90.1-1.6
Na content in liver0.20.30.9-0.5-0.40.30.30.40.60.4-0.0-1.0-0.7
Rb content in liver1.41.72.4-1.3-1.41.31.31.51.21.5-1.4-0.41.5
Se content in liver5.46.68.82.82.7-2.8-3.0-2.7-2.4-2.82.61.6-1.9
Sr content in liver0.10.10.40.20.3-0.3-0.2-0.2-0.2-0.40.4-0.5-0.6
Zn content in liver5.25.77.1-2.7-2.62.62.52.62.62.5-2.3-1.91.3
Bone: minimum diameter1.22.25.4-1.1-1.41.41.31.21.21.3-1.91.12.3
Time in familiar zone, hab. session 10.10.10.40.20.1-0.2-0.30.0-0.00.1-0.10.70.5
Time in novel zone, hab. session 10.00.00.10.20.2-0.10.0-0.3-0.2-0.30.10.2-0.1
Total zone transitions, hab. session 10.10.10.9-0.10.00.10.10.10.20.10.3-0.9-0.5
Total locomotion distance, hab. session 10.30.52.70.60.4-0.5-0.6-0.6-0.4-0.5-0.01.70.4
Locomotion velocity, hab. session 10.20.21.50.40.2-0.3-0.4-0.4-0.2-0.3-0.11.20.4
Time in familiar zone, hab. session 22.42.54.0-1.4-1.51.51.61.81.61.8-1.7-0.32.0
Time in novel zone, hab. session 21.41.42.80.91.0-1.1-1.1-1.4-1.1-1.41.3-0.1-1.7
Total zone transitions, hab. session 20.81.04.0-1.1-0.91.00.80.81.00.8-0.4-2.0-0.5
Total locomotion distance, hab. session 20.20.21.0-0.2-0.40.20.10.00.20.0-0.61.00.8
Locomotion velocity, hab. session 20.20.21.3-0.1-0.30.1-0.0-0.10.0-0.1-0.61.10.7
Novel to familiar place preference ratio0.10.10.5-0.1-0.00.1-0.1-0.2-0.2-0.20.2-0.5-0.7
Novelty place preference0.10.10.60.00.1-0.1-0.3-0.3-0.3-0.30.3-0.4-0.8
Time in novel zone, NPP test0.10.10.4-0.2-0.10.1-0.1-0.1-0.0-0.10.1-0.5-0.6
Total zone transitions, NPP test0.10.10.7-0.00.1-0.1-0.1-0.1-0.1-0.10.4-0.9-0.6
Total locomotion distance, NPP test0.70.92.10.90.7-1.0-1.1-1.2-0.8-1.10.51.5-0.3
Locomotion velocity, NPP test1.21.72.81.31.1-1.4-1.4-1.6-1.2-1.50.81.7-0.6
Intraocular pressure0.30.42.4-0.6-0.40.50.40.30.50.40.1-1.5-0.7
Delta distance traveled before/after self-admin0.10.20.50.10.2-0.2-0.3-0.2-0.3-0.30.5-0.7-0.6
Delta ambulatory time before/after self-admin0.30.41.30.20.4-0.3-0.4-0.3-0.4-0.40.8-1.0-1.2
Parametrial fat weight0.20.42.50.40.3-0.2-0.1-0.5-0.5-0.5-0.31.60.8
Pavlov. Cond. lever latency1.51.93.01.31.4-1.3-1.1-1.6-1.7-1.61.40.4-1.6
Pavlov. Cond. magazine entry latency3.44.45.5-2.2-2.32.32.12.22.42.2-2.2-1.11.8
Pavlov. Cond. change in total contacts0.90.91.8-1.0-1.11.00.81.01.31.0-1.0-0.50.7
Pavlov. Cond. index score3.64.56.2-2.1-2.32.11.92.42.52.3-2.2-0.72.2
Pavlov. Cond. latency score3.54.46.1-2.1-2.22.11.92.32.52.3-2.2-0.82.1
Pavlov. Cond. lever contacts1.72.03.3-1.2-1.41.21.01.61.81.6-1.5-0.11.8
Pavlov. Cond. magazine entry number3.94.96.92.32.4-2.3-2.2-2.4-2.6-2.42.21.3-1.7
Pavlov. Cond. intertrial magazine entries2.63.14.41.91.8-2.1-2.1-1.8-1.8-1.81.81.1-1.3
Pavlov. Cond. lever-magazine prob. diff.2.93.65.0-1.9-2.01.91.62.12.22.1-2.0-0.62.1
Pavlov. Cond. response bias1.51.82.9-1.2-1.41.21.01.51.71.5-1.4-0.11.6
Pavlov. Cond. lever latency18.525.031.85.65.5-5.5-5.5-5.2-5.1-5.14.74.3-2.7
Pavlov. Cond. magazine entry latency4.85.67.3-2.7-2.52.72.72.42.32.3-2.0-2.70.8
Pavlov. Cond. change in total contacts12.216.722.1-4.7-4.54.44.54.14.44.1-3.7-4.11.6
Pavlov. Cond. index score14.718.824.5-5.0-4.74.84.84.54.54.4-4.0-4.12.0
Pavlov. Cond. latency score13.216.421.5-4.6-4.44.54.54.24.24.1-3.7-4.01.7
Pavlov. Cond. lever contacts19.727.034.3-5.9-5.65.75.75.45.35.4-4.9-4.52.8
Pavlov. Cond. magazine entry number6.78.111.33.33.0-3.1-3.1-2.9-3.0-2.82.33.4-0.7
Pavlov. Cond. intertrial magazine entries0.40.62.3-0.1-0.40.10.10.30.40.4-0.81.51.5
Pavlov. Cond. lever-magazine prob. diff.13.617.322.7-4.8-4.54.64.54.24.44.2-3.8-3.91.8
Pavlov. Cond. response bias20.127.334.6-5.9-5.75.85.75.45.45.4-4.9-4.62.8
Time in closed arm before self-admin0.40.53.3-0.4-0.30.40.30.40.50.50.2-1.8-0.4
Time in closed arm after self-admin0.90.91.51.11.1-1.0-1.0-0.9-0.9-0.91.20.1-0.6
Time in open arm before self-admin2.42.63.11.71.7-1.8-1.7-1.5-1.6-1.61.41.7-1.3
Time in open arm after self-admin1.01.12.0-1.1-1.11.11.21.10.90.9-1.40.31.1
Bone: periosteal estimation1.93.95.4-1.9-2.12.22.21.91.71.9-2.3-0.12.3
Bone: periosteal perimeter2.64.46.2-2.0-2.22.22.22.21.92.2-2.3-0.32.5
Bone: post-yield work0.81.11.6-1.0-1.01.21.21.21.01.1-1.1-0.31.3
Progressive ratio test 1 active lever presses0.50.50.60.70.7-0.8-0.7-0.7-0.7-0.70.70.3-0.8
Progressive ratio test 1 breakpoint0.30.30.40.60.6-0.6-0.6-0.6-0.6-0.60.60.4-0.6
Progressive ratio test 1 inactive lever presses0.10.10.1-0.4-0.30.40.30.30.20.2-0.4-0.20.1
Progressive ratio test 2 active lever presses1.11.21.5-1.2-1.21.21.21.21.21.2-1.1-0.60.7
Progressive ratio test 2 breakpoint1.21.31.7-1.3-1.21.21.31.31.31.3-1.2-0.60.7
Progressive ratio test 2 inactive lever presses0.40.40.7-0.7-0.70.80.80.70.60.6-0.6-0.60.6
Incentive Sensitization - Responses3.03.13.7-1.9-1.91.91.91.91.81.8-1.8-1.01.3
Incentive Sensitization - Breakpoint2.82.93.5-1.9-1.81.81.81.81.81.8-1.7-1.11.2
Sum of active levers in priming session hrs 5-60.10.10.20.30.2-0.3-0.5-0.4-0.3-0.30.20.0-0.1
Progressive ratio0.10.10.4-0.1-0.00.0-0.00.0-0.2-0.00.2-0.7-0.4
Food seeking constrained by brief footshock1.51.82.5-1.5-1.61.51.51.31.41.3-1.6-0.41.1
Seeking ratio, punishment vs. effort1.11.42.2-1.2-1.31.21.21.11.31.1-1.50.31.3
Retroperitoneal fat weight1.34.423.61.81.3-1.5-1.5-1.7-1.8-1.8-0.14.91.4
Reaction time number correct0.20.31.00.30.3-0.4-0.4-0.2-0.3-0.20.7-1.0-0.8
Reaction time mean minus median1.31.72.5-1.3-1.41.51.61.31.31.3-1.4-0.51.3
Reaction time mean minus median AUC1.21.62.2-1.3-1.31.41.51.21.21.3-1.2-0.91.1
Reaction time num false alarms1.41.93.21.51.4-1.5-1.4-1.4-1.7-1.51.01.8-0.4
Reaction time num false alarms AUC1.11.52.01.31.2-1.4-1.3-1.2-1.4-1.31.01.3-0.6
Reaction time trials correct on left0.20.31.00.30.3-0.4-0.4-0.2-0.3-0.20.7-1.0-0.8
Reaction time trials on left0.20.31.00.30.3-0.4-0.4-0.3-0.4-0.20.7-1.0-0.8
Reaction time mean0.20.31.00.50.5-0.4-0.3-0.7-0.8-0.80.11.00.2
Reaction time mean AUC0.60.91.41.00.9-0.8-0.7-1.1-1.1-1.20.61.1-0.1
Median of all reaction times0.81.11.91.11.1-1.0-0.9-1.3-1.3-1.40.71.2-0.3
Reaction time omissions0.10.10.30.20.2-0.2-0.1-0.5-0.6-0.50.10.3-0.1
Reaction time false alarm rate1.01.42.81.21.1-1.2-1.1-1.2-1.3-1.30.71.7-0.3
Reaction time premature initiation rate3.74.97.1-2.1-2.32.42.42.12.22.2-2.70.32.6
Reaction time premature initiations2.43.44.3-1.8-1.92.12.01.91.82.0-2.0-0.51.9
Std. dev. reaction times0.70.91.6-0.9-1.01.01.10.80.70.8-1.30.31.2
Reaction time trials completed0.20.31.00.30.3-0.4-0.4-0.3-0.4-0.20.7-1.0-0.8
Reaction time trials AUC0.10.20.80.20.2-0.3-0.3-0.2-0.3-0.20.6-0.9-0.7
Run reversals in cocaine runway, females1.41.45.3-0.4-0.60.60.60.60.40.6-1.52.32.0
Run reversals in cocaine runway, males0.00.00.00.20.2-0.0-0.0-0.00.00.10.10.10.1
Latency to leave start box in cocaine runway1.92.12.61.31.4-1.5-1.6-1.4-1.5-1.41.21.3-1.5
Latency to leave start box in cocaine runway, F1.01.11.70.91.0-1.1-1.2-1.0-1.0-1.00.71.3-1.1
Latency to leave start box in cocaine runway, M0.50.50.80.70.8-0.7-0.7-0.6-0.8-0.60.8-0.1-0.9
Std. dev. time between licks in bursts1.92.23.4-1.4-1.61.31.21.61.71.7-1.80.51.7
Total sessions with >9 infusions2.02.23.1-1.6-1.51.51.51.81.61.6-1.1-1.70.5
Short access day 1 total inactive lever presses0.40.50.60.70.7-0.7-0.7-0.7-0.8-0.80.60.4-0.3
Short access day 10 total inactive lever presses0.20.20.30.50.5-0.5-0.4-0.5-0.5-0.50.5-0.0-0.4
Short access day 1 total infusions1.92.12.6-1.6-1.61.51.61.61.51.5-1.4-1.00.9
Short access day 10 total infusions0.70.71.0-1.0-1.00.90.91.00.90.9-1.0-0.20.7
Short access total infusions0.70.81.1-1.0-1.00.90.91.00.90.9-1.0-0.30.8
Short access day 1 locomotion1.11.24.4-1.2-0.90.90.90.91.01.0-0.3-2.1-0.8
Short access day 10 total locomotion0.20.30.4-0.6-0.50.50.40.60.60.6-0.4-0.40.1
Short access total locomotion0.10.10.2-0.3-0.20.20.20.30.40.4-0.0-0.5-0.3
One hour access (0.3 mA shock)1.82.12.4-1.5-1.51.61.51.51.61.6-1.3-1.30.9
Compulsive drug intake0.20.20.9-0.00.1-0.1-0.1-0.2-0.1-0.10.4-1.0-0.7
One hour access (shock baseline)1.11.31.5-1.2-1.21.21.21.21.21.2-1.1-0.80.8
Social response proportion0.50.51.30.80.6-0.7-0.7-0.8-0.7-0.80.41.10.2
Social responses0.30.42.50.50.3-0.5-0.4-0.5-0.5-0.4-0.11.60.7
Social time4.45.87.42.52.5-2.5-2.4-2.7-2.6-2.72.51.3-2.1
Soleus weight0.51.45.0-0.4-0.70.70.70.60.30.6-1.52.02.2
Bone: stiffness0.10.10.4-0.1-0.10.30.3-0.0-0.0-0.0-0.40.60.7
Tibialis anterior weight0.20.81.4-0.9-0.91.00.90.80.80.8-1.20.31.2
Time to tail flick, vehicle, before self-admin0.20.21.10.30.10.1-0.10.0-0.1-0.0-0.10.61.0
Time to tail flick, vehicle, after self-admin1.61.72.9-1.4-1.31.31.51.31.31.3-1.0-1.70.7
Time to tail flick, test, before self-admin0.40.40.6-0.6-0.60.60.50.70.70.8-0.70.20.6
Time to tail flick, test, after self-admin0.40.40.6-0.6-0.60.50.60.70.70.7-0.80.40.5
Delta time to tail flick, vehicle, before/after SA1.51.54.9-1.4-1.10.91.21.01.11.1-0.6-2.2-0.9
Delta time to tail flick, test, before/after SA0.40.40.90.50.6-0.6-0.5-0.6-0.6-0.60.60.1-1.0
Tibia length1.02.98.5-1.8-1.61.71.81.61.71.7-0.8-2.9-0.4
Ambulatory time before self-admin0.80.81.01.01.0-0.9-1.0-1.0-0.9-0.90.90.6-0.7
Ambulatory time after self-admin2.93.14.51.81.9-1.7-1.9-1.9-1.9-1.92.10.0-1.8
Bone: tissue strength0.70.72.00.50.7-0.5-0.5-0.7-0.6-0.71.1-0.9-1.4
Total heroin consumption0.10.10.3-0.3-0.30.40.10.10.30.2-0.2-0.50.1
Bone: trabecular number0.50.81.41.21.1-0.8-0.8-0.8-1.0-0.80.90.80.3
Bone: trabecular spacing0.50.71.8-1.0-0.80.70.60.71.00.8-0.4-1.3-0.7
Bone: trabecular thickness0.30.31.50.30.1-0.00.1-0.1-0.3-0.1-0.31.11.2
Bone: trabecular tissue density0.50.73.20.80.7-0.8-0.6-0.9-0.6-0.80.21.80.1
Water consumed over 24 hours0.91.11.81.41.2-1.2-1.3-0.9-1.0-0.91.01.10.1
Number of responses in last shaping day0.70.71.8-0.6-0.80.80.70.80.80.8-1.00.51.3