Hub : Genes

Mogat2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Mogat2 0.5 0.15 0.0e+00 0.43 0.45 0.44 0.45 9.6e-20 8.3e-21 3.1e-20 1.1e-20
2 BLA gene expression Mogat2 0.25 0.12 1.2e-11 0.17 0.19 0.17 0.18 3.7e-09 3.0e-10 1.8e-09 1.1e-09
3 PL gene expression Mogat2 0.42 0.15 0.0e+00 0.36 0.36 0.37 0.37 2.1e-41 1.6e-41 4.7e-42 7.8e-42
4 OFC gene expression Mogat2 0.2 0.13 4.7e-03 0.06 0.02 -0.01 0.02 1.4e-02 1.2e-01 5.3e-01 1.1e-01
5 Brain gene expression Mogat2 0.05 0.03 3.7e-04 0.04 0.03 0.04 0.04 5.5e-05 3.7e-04 3.3e-04 2.1e-04
6 pVTA gene expression Mogat2 0.24 0.11 0.0e+00 0.27 0.26 0.26 0.27 4.1e-22 5.7e-21 2.2e-21 8.9e-22
7 NAcc gene expression Mogat2 0.31 0.13 0.0e+00 0.35 0.34 0.34 0.34 5.8e-55 8.4e-54 3.4e-54 4.2e-54
8 IL gene expression Mogat2 0.37 0.16 1.2e-04 0.09 0.1 0.07 0.08 3.1e-03 2.7e-03 9.7e-03 6.9e-03
9 NAcc intron excision ratio chr1_162948977_162957777 0.2 0.09 0.0e+00 0.16 0.16 0.16 0.15 7.4e-23 8.3e-23 5.0e-23 2.0e-22
10 pVTA intron excision ratio chr1_162934832_162936910 0.22 0.1 1.0e-14 0.19 0.19 0.19 0.19 7.2e-15 5.2e-15 4.8e-15 1.8e-15
11 NAcc intron excision ratio chr1_162984434_162985025 0.2 0.09 0.0e+00 0.15 0.2 0.2 0.2 1.9e-22 2.7e-29 1.7e-29 1.3e-29
12 Adipose gene expression Mogat2 0.23 0.1 0.0e+00 0.2 0.22 0.21 0.22 6.0e-22 7.5e-24 6.7e-23 1.6e-23

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.10.21.10.30.40.4-0.10.10.10.00.1-0.50.10.31.0
Area under the delay curve0.00.00.3-0.1-0.2-0.20.0-0.1-0.3-0.2-0.10.1-0.00.1-0.5
BMI with tail0.20.73.0-0.1-0.7-0.4-0.4-0.4-0.5-0.3-0.9-0.31.71.21.1
BMI without tail0.92.76.9-0.9-1.5-1.1-1.2-1.3-1.4-1.2-1.9-1.61.52.52.6
Body weight0.52.04.7-0.6-1.4-0.9-1.0-0.8-1.0-0.8-1.8-1.02.02.22.1
Weight adjusted by age0.40.50.8-0.6-0.8-0.6-0.8-0.7-0.7-0.8-0.9-0.7-0.10.90.7
Bone surface1.83.35.6-1.6-1.6-1.5-2.1-1.8-1.7-1.7-1.8-2.2-0.72.02.4
Bone volume1.01.94.6-1.0-1.0-1.0-1.4-1.3-1.2-1.3-1.3-1.9-0.41.62.1
Breakpoint value in progressive ratio session1.31.52.51.11.21.11.41.21.21.21.31.40.4-1.4-1.6
Number of licking bursts2.84.66.82.62.22.42.22.22.12.41.92.22.6-1.3-0.9
Context. condit. distance diff. score2.42.94.1-1.9-1.7-2.0-2.0-1.9-2.0-1.9-1.4-1.9-1.70.90.3
Locomotion velocity, session 11.01.02.00.81.10.91.30.60.80.91.21.0-0.5-1.4-1.3
Locomotion distance, session 10.30.42.0-0.7-0.4-0.6-0.1-0.7-0.3-0.2-0.00.0-1.4-0.7-0.9
Locomotion velocity, session 20.00.00.1-0.1-0.10.00.30.00.10.0-0.00.10.00.0-0.0
Locomotion distance, session 20.10.20.8-0.6-0.4-0.4-0.1-0.6-0.5-0.5-0.3-0.3-0.90.0-0.0
Locomotion velocity, session 30.30.31.7-0.6-0.3-0.5-0.3-0.6-0.4-0.3-0.1-0.1-1.3-0.4-0.7
Locomotion distance, session 30.50.63.3-0.8-0.4-0.7-0.4-0.8-0.6-0.6-0.1-0.2-1.8-0.5-0.8
Stereotopy head waving bouts, day 30.20.31.20.60.40.40.60.50.40.40.20.21.10.10.3
Stereotopy head waving duration, day 30.20.20.3-0.5-0.4-0.4-0.4-0.5-0.6-0.5-0.4-0.5-0.50.30.3
Locomotion velocity, session 70.40.40.90.50.60.60.50.70.70.60.70.9-0.0-0.8-0.9
Locomotion distance, session 70.10.10.10.30.20.30.20.20.10.10.20.40.3-0.2-0.4
Stereotopy head waving bouts, day 71.21.42.8-1.5-1.3-1.3-1.0-1.3-1.4-1.3-1.0-1.0-1.70.50.2
Stereotopy head waving duration, day 72.02.43.6-1.9-1.7-1.6-1.5-1.7-1.7-1.7-1.5-1.5-1.61.00.9
Locomotion velocity, session 81.51.82.4-1.4-1.3-1.3-1.5-1.5-1.5-1.4-1.2-1.6-0.91.11.0
Locomotion distance, session 81.62.43.4-1.9-1.6-1.8-1.5-1.8-1.8-1.7-1.3-1.5-1.70.70.2
Degree of sensitization distance0.50.53.50.3-0.20.2-0.10.20.0-0.0-0.5-0.21.91.01.1
Degree of sensitization stereotypy2.83.15.8-2.3-1.9-1.9-1.7-2.0-1.9-1.8-1.5-1.4-2.40.70.3
Conditioned locomotion0.20.20.50.30.50.30.40.40.40.40.60.3-0.6-0.7-0.7
Cocaine response after cond. corrected1.72.13.21.51.21.31.31.61.61.81.11.71.8-1.0-1.0
Cocaine response after cond. not corrected0.91.01.80.90.80.70.91.11.21.30.81.30.9-1.0-1.1
Cocaine response before conditioning0.91.13.1-1.3-0.9-1.1-0.9-1.2-1.1-1.0-0.7-1.1-1.80.30.3
Saline control response1.31.82.5-1.5-1.6-1.5-1.4-1.3-1.3-1.2-1.5-1.3-0.71.31.1
Bone: connectivity density0.20.41.4-0.4-0.2-0.2-0.7-0.4-0.4-0.4-0.3-1.0-0.60.61.2
Bone: cortical apparent density0.91.22.61.41.21.41.21.11.00.91.01.01.6-0.4-0.0
Bone: cortical area0.61.02.0-0.8-0.9-0.8-1.2-0.9-0.7-0.9-1.1-1.20.21.31.4
Bone: cortical porosity0.30.41.8-0.6-0.3-0.6-0.3-0.2-0.2-0.10.00.0-1.3-0.6-1.1
Bone: cortical porosity0.30.31.9-0.6-0.3-0.6-0.2-0.3-0.3-0.2-0.0-0.2-1.4-0.5-0.9
Bone: cortical thickness0.20.40.60.70.70.80.60.70.80.70.60.50.5-0.5-0.2
Bone: cortical thickness0.00.00.2-0.3-0.2-0.20.00.10.0-0.1-0.1-0.0-0.4-0.2-0.2
Bone: cortical tissue density1.01.32.31.51.31.41.31.11.10.91.11.11.5-0.5-0.1
Condit. Reinf. active minus inactive responses0.60.71.7-0.6-0.7-0.6-0.6-0.7-0.8-0.9-0.9-1.10.31.21.3
Condit. Reinf. active-inactive response ratio1.81.93.6-1.0-1.3-1.1-1.3-1.2-1.3-1.4-1.5-1.70.31.81.9
Condit. Reinf. active responses0.10.10.4-0.1-0.2-0.1-0.0-0.2-0.3-0.4-0.3-0.40.20.50.6
Condit. Reinf. inactive responses0.20.30.60.40.50.40.80.50.40.50.60.6-0.2-0.6-0.7
Incentive salience index mean0.50.71.3-0.6-0.7-0.6-0.5-0.8-0.9-1.0-0.9-1.00.11.11.1
Condit. Reinf. lever presses0.30.40.6-0.6-0.6-0.5-0.2-0.8-0.7-0.8-0.6-0.6-0.40.60.7
Condit. Reinf. active minus inactive responses6.38.111.1-3.3-3.3-3.3-3.2-3.1-3.0-2.9-3.1-2.5-1.72.41.7
Condit. Reinf. active-inactive response ratio0.70.81.4-1.2-1.2-1.2-1.0-1.0-1.0-0.9-1.0-0.5-0.90.50.1
Condit. Reinf. active responses9.513.217.4-4.1-4.2-4.0-4.1-3.8-3.7-3.6-4.1-3.4-1.73.42.8
Condit. Reinf. inactive responses6.28.09.9-2.9-3.1-2.9-3.1-2.9-2.8-2.7-3.1-3.0-0.93.02.8
Condit. Reinf. lever presses17.424.132.3-5.7-5.5-5.4-5.6-5.2-5.2-5.1-5.2-4.7-3.44.13.0
Condit. Reinf. lever reinforcers received10.414.519.2-4.3-4.4-4.2-4.3-4.1-3.9-3.9-4.2-3.6-2.03.42.7
Conditioned reinforcement - actives0.50.92.4-1.2-0.9-1.1-0.9-0.9-0.9-0.9-0.7-0.9-1.50.30.1
Conditioned reinforcement - inactives0.60.91.50.80.90.90.90.91.01.00.91.20.2-1.0-1.1
Conditioned locomotion0.60.74.7-0.9-0.4-0.8-0.4-0.4-0.5-0.5-0.0-0.3-2.2-0.7-1.0
Patch foraging indifference point 0 sec4.78.710.9-3.3-3.2-3.2-3.1-3.2-3.2-3.2-3.0-2.9-2.52.41.7
Patch foraging indifference point AUC0.50.71.2-0.6-0.8-0.6-0.8-0.8-0.9-0.7-1.0-0.70.71.11.0
Delay disc. indifference point, 0s delay0.91.01.9-1.1-1.1-1.1-0.7-1.2-1.4-1.3-1.0-0.9-0.60.70.3
Delay disc. indifference point, 16s delay0.20.20.40.30.30.30.40.60.40.40.40.5-0.1-0.4-0.6
Delay disc. indifference point, 2s delay1.01.12.2-1.1-1.3-1.3-0.8-1.3-1.5-1.2-1.0-0.5-0.70.6-0.5
Delay disc. indifference point, 24s delay0.91.01.71.21.11.20.91.31.31.20.90.91.0-0.50.1
Delay disc. indifference point, 4s delay0.70.81.8-0.8-1.0-1.0-0.4-1.2-1.4-1.2-0.9-0.50.10.7-0.1
Delay disc. indifference point, 8s delay0.20.30.4-0.6-0.6-0.6-0.6-0.4-0.7-0.5-0.6-0.5-0.20.60.1
Indifference point function ln k0.50.95.5-1.1-0.6-0.9-0.6-0.7-0.7-0.9-0.3-0.7-2.4-0.2-0.6
Indifference point function log k0.50.95.5-1.1-0.6-0.9-0.6-0.7-0.7-0.9-0.3-0.7-2.4-0.2-0.6
Patch foraging total patch changes 0 sec3.97.39.2-3.0-2.9-3.0-2.9-3.0-3.0-2.9-2.8-2.6-2.32.21.5
Patch foraging total patch changes 12 sec3.03.94.9-1.8-2.1-1.9-2.1-2.1-2.1-2.1-2.2-2.1-0.32.12.0
Patch foraging total patch changes 18 sec3.65.56.9-2.2-2.4-2.3-2.3-2.6-2.6-2.5-2.5-2.5-0.72.42.3
Patch foraging total patch changes 24 sec0.40.71.2-0.9-1.1-1.0-0.9-1.0-1.0-0.8-1.0-0.5-0.30.70.4
Patch foraging total patch changes 6 sec1.52.33.6-1.7-1.6-1.6-1.9-1.7-1.7-1.5-1.5-1.4-1.21.10.8
Patch foraging time to switch 0 sec3.57.18.42.92.92.92.82.82.92.82.82.71.8-2.4-2.0
Patch foraging water rate 0 sec2.45.16.8-2.6-2.5-2.6-2.4-2.4-2.4-2.3-2.3-2.2-2.01.71.2
Patch foraging water rate 12 sec1.02.15.0-1.7-1.4-1.6-1.4-1.6-1.5-1.4-1.2-1.2-2.20.70.5
Patch foraging water rate 18 sec0.60.91.1-1.0-1.0-1.0-0.9-1.0-1.1-1.0-0.9-0.9-1.10.70.7
Patch foraging water rate 24 sec0.60.85.0-1.0-0.6-0.9-0.6-0.7-0.7-0.7-0.3-0.6-2.2-0.3-0.5
Patch foraging water rate 6 sec0.40.62.5-0.9-0.7-0.8-0.9-0.7-0.6-0.7-0.5-0.6-1.60.20.1
Seeking ratio, delayed vs. immediate footshock2.22.63.71.81.91.91.71.61.81.81.81.50.8-1.5-0.7
Distance traveled before self-admin0.30.31.00.70.60.70.60.40.40.60.50.51.0-0.2-0.1
Distance traveled after self-admin2.22.83.91.51.81.61.81.71.71.72.01.70.1-2.0-1.6
Extensor digitorum longus weight0.20.93.3-0.1-0.5-0.2-0.5-0.3-0.4-0.5-1.0-0.71.41.61.8
Bone: elastic displacement2.02.33.21.61.61.71.31.81.71.81.61.60.9-1.4-1.1
Bone: elastic work2.02.63.71.71.81.81.51.91.91.81.71.60.8-1.5-1.1
Bone: endosteal estimation2.24.87.1-1.9-2.3-2.0-2.3-2.2-2.1-2.2-2.5-2.40.02.72.6
Bone: endosteal perimeter2.96.27.8-2.4-2.6-2.5-2.6-2.5-2.4-2.5-2.8-2.8-0.62.82.7
Epididymis fat weight0.30.92.11.10.70.91.01.00.91.10.61.21.5-0.6-0.6
Delta time in closed arm before/after self-admin0.60.53.60.80.30.70.40.40.30.40.00.31.90.60.8
Delta time in open arm before/after self-admin3.13.04.5-1.8-1.8-1.8-2.1-1.7-1.6-1.7-1.9-1.9-0.81.71.6
Diff in mean of infusions in LGA sessions6.17.48.93.02.92.93.02.82.82.82.82.92.0-2.4-2.2
Delay discount exponential model param0.00.00.30.10.20.2-0.10.10.30.20.1-0.2-0.0-0.00.5
Extinction: sum of active levers before priming0.00.00.10.0-0.1-0.00.1-0.00.10.1-0.10.20.30.10.1
Active lever presses in extinction session 61.01.05.8-1.0-0.4-0.9-0.4-0.4-0.4-0.50.10.1-2.4-1.0-1.7
Bone: final force0.00.00.20.00.00.1-0.40.00.2-0.0-0.1-0.30.20.20.3
Bone: final moment0.10.20.5-0.2-0.2-0.1-0.7-0.3-0.1-0.3-0.3-0.60.10.50.7
Food consumed during 24 hour testing period2.23.14.3-2.0-1.6-1.7-1.4-2.1-2.0-1.9-1.4-1.9-2.11.21.3
Glucose0.00.00.10.20.10.20.10.10.00.20.10.30.4-0.1-0.2
Heart weight0.61.01.8-1.2-1.1-1.0-1.4-1.0-0.9-0.9-1.0-1.0-0.90.70.6
Delay discount hyperbolic model param0.10.10.30.20.40.30.10.30.50.40.30.0-0.1-0.30.4
Intermittent access intake day 1-15 change0.40.92.7-1.2-0.9-1.0-1.1-0.9-0.9-0.9-0.7-0.8-1.60.3-0.1
Intermittent access intake escalation0.51.13.0-1.3-1.0-1.2-1.2-1.1-1.1-1.1-0.8-0.9-1.70.3-0.0
Intermittent access intake escalation 20.91.02.1-1.2-1.1-1.1-1.2-1.1-1.1-1.0-0.9-0.8-1.40.50.2
Intermitt. access day 1 inactive lever presses0.83.14.41.81.71.81.91.91.91.91.72.11.3-1.5-1.4
Intermitt. access day 15 inactive lever presses1.42.93.81.71.81.81.91.81.81.81.82.00.6-1.7-1.2
Intermitt. access escalation Index0.00.00.10.00.10.1-0.00.20.20.20.0-0.10.20.10.3
Intermittent access day 1 total infusions0.40.60.8-0.9-0.8-0.7-0.9-0.8-0.8-0.8-0.7-0.8-0.70.60.7
Intermittent access day 15 total infusions0.81.22.6-1.4-1.1-1.1-1.2-1.1-1.1-1.1-0.9-1.0-1.60.50.3
Intermittent access terminal intake (last 3 days)1.51.92.8-1.7-1.4-1.5-1.6-1.5-1.5-1.5-1.3-1.4-1.60.90.7
Intermittent access total infusions1.21.41.8-1.3-1.2-1.2-1.3-1.2-1.2-1.2-1.2-1.3-0.91.01.0
Intermittent access day 1 locomotion0.10.10.4-0.3-0.1-0.2-0.3-0.2-0.2-0.2-0.1-0.4-0.60.00.1
Intermittent access day 15 total locomotion0.40.83.3-1.1-0.7-0.9-0.9-0.8-0.8-0.8-0.5-0.7-1.80.0-0.2
Intermittent access total locomotion0.40.50.9-0.9-0.7-0.7-0.9-0.7-0.7-0.7-0.6-0.8-1.00.40.4
Intermittent access standard deviation0.30.71.3-0.6-0.8-0.7-0.9-0.7-0.8-0.8-0.9-0.80.21.11.2
Left kidney weight0.41.73.6-0.8-1.3-1.0-0.9-1.3-1.4-1.2-1.5-1.21.01.91.9
Right kidney weight0.52.45.0-1.0-1.5-1.2-1.1-1.4-1.5-1.4-1.8-1.51.02.22.2
Cocaine induced anxiety0.81.11.71.31.21.31.21.21.11.11.00.81.1-0.6-0.0
Post-drug Anxiety1.21.21.91.41.31.31.11.31.21.21.00.91.2-0.5-0.1
Baseline Anxiety0.20.20.4-0.4-0.5-0.5-0.6-0.6-0.5-0.5-0.5-0.5-0.20.50.3
Tail length1.24.612.4-1.2-1.9-1.5-1.7-1.8-1.8-1.7-2.4-2.31.53.23.5
Length with tail0.62.55.9-1.0-1.6-1.2-1.3-1.3-1.4-1.3-1.9-1.51.12.32.4
Length without tail0.20.50.90.70.60.60.90.80.70.80.60.90.5-0.6-0.7
Times rat made contact with spout0.30.31.60.30.10.30.1-0.1-0.10.1-0.2-0.21.20.81.2
Lifetime Intake1.21.52.0-1.4-1.3-1.3-1.4-1.3-1.3-1.3-1.2-1.3-1.20.90.7
Liver weight, left0.20.31.90.2-0.20.00.20.20.00.2-0.40.01.40.70.9
Liver weight, right0.81.36.41.20.71.11.11.00.90.90.30.62.50.61.2
Locomotor activity1.11.72.6-1.3-1.2-1.1-1.3-1.4-1.3-1.4-1.2-1.6-1.31.31.4
Locomotor testing distance2.23.95.0-2.0-2.0-1.9-1.9-2.0-2.1-2.0-2.1-2.2-1.22.12.1
Locomotor testing rearing0.91.83.0-1.2-1.4-1.2-1.3-1.3-1.3-1.2-1.6-1.5-0.11.71.7
Locomotion in novel chamber0.40.52.3-0.8-0.5-0.7-0.5-0.5-0.7-0.8-0.3-0.7-1.50.1-0.1
Locomotion in novel chamber post-restriction1.42.28.4-1.8-1.4-1.8-1.4-1.3-1.3-1.4-1.0-0.9-2.90.3-0.6
Fecal boli incidents, locomotor time 10.20.31.2-0.7-0.4-0.6-0.5-0.7-0.5-0.4-0.2-0.6-1.1-0.00.1
Change in fecal boli incidents, locomotor task1.01.01.51.00.91.01.10.81.11.20.91.20.8-0.9-0.9
Time >=10cm from walls, locomotor time 11.11.14.8-1.3-1.0-1.2-1.0-1.0-0.8-1.1-0.7-0.6-2.20.1-0.5
Bouts of movement, locomotor time 10.00.00.1-0.2-0.1-0.20.0-0.3-0.00.1-0.00.3-0.0-0.2-0.2
Total resting periods, locomotor time 10.20.20.50.10.30.20.40.10.40.50.40.6-0.2-0.7-0.5
Rest time, locomotor task time 10.70.91.50.71.00.81.10.90.91.11.11.10.2-1.2-1.0
Distance moved, locomotor task time 11.01.53.0-0.8-1.1-0.9-1.3-1.0-1.3-1.4-1.3-1.50.31.71.6
Vertical activity count, locomotor time 10.92.23.3-1.2-1.5-1.3-1.7-1.4-1.5-1.7-1.6-1.7-0.21.81.4
Time >=10cm from walls, locomotor time 20.60.81.5-1.1-1.1-1.2-0.8-1.1-1.0-0.9-0.9-0.8-0.80.40.1
Bouts of movement, locomotor time 20.40.61.3-0.8-1.0-0.9-0.8-1.1-1.2-0.6-0.9-0.3-0.30.50.0
Total resting periods, locomotor time 20.20.30.9-0.5-0.7-0.6-0.4-0.9-0.9-0.4-0.60.1-0.10.2-0.3
Rest time, locomotor task time 21.82.33.31.81.71.81.61.41.41.71.61.51.4-1.2-0.8
Distance moved, locomotor task time 22.53.04.4-2.0-2.0-2.1-1.8-1.7-1.7-1.9-1.9-1.9-1.01.51.1
Vertical activity count, locomotor time 21.82.53.3-1.6-1.8-1.8-1.6-1.5-1.5-1.8-1.8-1.8-0.31.71.3
Light reinforcement 10.82.02.91.71.51.71.61.61.41.51.31.31.6-0.6-0.3
Light reinforcement 20.20.20.40.30.50.50.60.60.50.60.50.5-0.0-0.5-0.3
Bone: marrow area2.04.36.6-1.8-2.1-1.9-2.1-2.0-1.9-2.0-2.3-2.30.22.62.5
Bone: maximum diameter2.85.26.9-2.2-2.4-2.3-2.6-2.2-2.1-2.2-2.5-2.5-0.62.42.3
Bone: maximum force0.10.20.5-0.3-0.3-0.2-0.7-0.3-0.2-0.4-0.4-0.60.10.50.6
Bone: maximum moment0.30.40.9-0.5-0.5-0.4-0.9-0.5-0.5-0.6-0.7-0.90.00.80.9
Mean time between licks in bursts2.86.88.6-2.5-2.9-2.6-2.4-2.9-2.9-2.7-2.9-2.6-0.52.82.6
Mean num. licks in bursts2.94.55.9-2.4-2.2-2.3-2.2-2.3-2.2-2.4-2.0-2.3-2.11.61.4
Cd content in liver0.10.21.20.50.20.30.30.20.20.30.00.31.10.20.2
Co content in liver1.61.82.6-1.2-1.4-1.3-1.3-1.4-1.5-1.6-1.5-1.4-0.21.51.3
Cu content in liver0.40.50.9-0.4-0.7-0.5-0.2-0.8-0.8-0.6-0.8-0.50.61.01.0
Fe content in liver0.10.10.20.30.20.20.20.20.30.40.20.40.2-0.3-0.4
K content in liver0.00.00.20.20.00.10.30.1-0.00.00.00.00.40.20.2
Mg content in liver0.10.10.2-0.3-0.3-0.3-0.0-0.3-0.4-0.3-0.1-0.0-0.4-0.1-0.3
Mn content in liver1.92.13.21.31.51.41.41.31.41.51.71.5-0.2-1.8-1.7
Na content in liver0.40.40.8-0.8-0.7-0.9-0.5-0.7-0.7-0.7-0.4-0.4-0.90.0-0.6
Rb content in liver0.80.91.6-0.9-0.8-0.8-0.9-0.8-1.0-0.9-0.9-1.2-0.61.11.3
Se content in liver7.38.611.53.13.13.03.42.93.03.03.23.11.6-2.9-2.6
Sr content in liver0.10.10.4-0.2-0.1-0.2-0.2-0.3-0.3-0.30.0-0.1-0.6-0.2-0.4
Zn content in liver2.93.34.3-1.9-2.0-1.9-1.7-2.0-2.1-1.9-1.9-1.8-0.81.71.5
Bone: minimum diameter1.42.56.2-0.9-1.4-1.1-1.3-1.5-1.3-1.4-1.8-1.71.22.32.5
Time in familiar zone, hab. session 10.10.10.30.20.10.20.40.1-0.2-0.2-0.1-0.20.60.40.5
Time in novel zone, hab. session 10.10.10.20.30.20.3-0.10.20.40.40.10.40.4-0.1-0.0
Total zone transitions, hab. session 10.10.10.7-0.20.1-0.0-0.1-0.2-0.2-0.20.2-0.1-0.8-0.4-0.4
Total locomotion distance, hab. session 10.30.53.20.80.40.60.60.40.50.60.10.41.80.30.5
Locomotion velocity, hab. session 10.20.21.70.50.20.30.40.20.40.40.00.21.30.30.4
Time in familiar zone, hab. session 22.82.94.7-1.5-1.6-1.4-1.7-1.7-1.8-1.9-1.7-2.2-0.62.02.0
Time in novel zone, hab. session 21.61.63.10.91.00.91.11.21.41.41.21.80.0-1.7-1.7
Total zone transitions, hab. session 20.70.92.9-1.2-0.9-1.1-0.7-1.0-1.0-0.9-0.5-0.5-1.7-0.2-0.6
Total locomotion distance, hab. session 20.20.31.1-0.1-0.4-0.3-0.1-0.3-0.2-0.1-0.6-0.21.10.80.8
Locomotion velocity, hab. session 20.20.31.60.0-0.3-0.10.0-0.2-0.10.0-0.5-0.11.20.70.7
Novel to familiar place preference ratio0.10.10.5-0.1-0.0-0.20.10.40.40.30.10.5-0.1-0.5-0.7
Novelty place preference0.20.20.60.00.1-0.10.30.50.50.40.20.6-0.1-0.6-0.7
Time in novel zone, NPP test0.10.10.4-0.2-0.1-0.20.10.20.20.20.00.4-0.3-0.4-0.6
Total zone transitions, NPP test0.10.20.8-0.10.1-0.00.2-0.00.10.10.30.3-0.9-0.7-0.7
Total locomotion distance, NPP test0.60.82.11.00.70.81.10.70.91.10.61.11.4-0.5-0.3
Locomotion velocity, NPP test1.01.52.81.31.01.11.41.11.31.50.91.51.7-0.8-0.6
Intraocular pressure0.30.42.3-0.6-0.3-0.4-0.4-0.4-0.3-0.2-0.00.1-1.5-0.5-0.9
Delta distance traveled before/after self-admin0.30.32.6-0.40.0-0.30.0-0.00.0-0.10.3-0.0-1.6-0.7-0.7
Delta ambulatory time before/after self-admin0.30.42.6-0.30.1-0.30.10.10.1-0.00.40.1-1.6-0.9-1.0
Parametrial fat weight0.30.62.10.90.60.80.50.90.90.90.50.81.5-0.2-0.2
Pavlov. Cond. lever latency2.02.53.61.51.51.41.21.91.91.81.51.81.0-1.6-1.7
Pavlov. Cond. magazine entry latency4.25.46.8-2.4-2.4-2.4-2.3-2.6-2.6-2.5-2.4-2.5-1.32.11.9
Pavlov. Cond. change in total contacts1.01.11.7-1.2-1.2-1.2-0.8-1.3-1.3-1.1-1.1-1.1-0.70.80.6
Pavlov. Cond. index score3.94.96.5-2.2-2.2-2.2-1.9-2.6-2.5-2.5-2.3-2.5-1.22.22.1
Pavlov. Cond. latency score3.74.76.3-2.2-2.2-2.1-1.9-2.5-2.4-2.4-2.2-2.4-1.32.12.0
Pavlov. Cond. lever contacts2.02.43.5-1.4-1.4-1.3-1.1-1.9-1.8-1.8-1.5-1.8-0.81.61.7
Pavlov. Cond. magazine entry number4.25.47.62.42.42.42.22.82.62.62.42.51.4-2.1-1.8
Pavlov. Cond. intertrial magazine entries2.42.93.81.81.81.81.91.81.82.01.81.80.7-1.6-1.3
Pavlov. Cond. lever-magazine prob. diff.3.24.05.2-1.9-2.0-1.9-1.7-2.3-2.2-2.2-2.0-2.3-1.02.02.0
Pavlov. Cond. response bias2.12.53.9-1.5-1.5-1.4-1.2-2.0-1.8-1.8-1.6-1.8-0.81.61.6
Pavlov. Cond. lever latency17.924.334.45.95.65.65.65.15.25.15.14.64.0-3.8-2.6
Pavlov. Cond. magazine entry latency4.55.47.9-2.8-2.5-2.7-2.7-2.4-2.4-2.4-2.2-2.2-2.31.40.7
Pavlov. Cond. change in total contacts9.715.623.1-4.8-4.5-4.6-4.4-4.2-4.2-4.1-4.1-3.4-3.62.71.5
Pavlov. Cond. index score13.418.025.7-5.1-4.8-4.9-4.8-4.5-4.6-4.4-4.4-3.9-3.63.01.9
Pavlov. Cond. latency score11.715.522.5-4.7-4.5-4.6-4.5-4.2-4.2-4.1-4.0-3.5-3.52.71.6
Pavlov. Cond. lever contacts16.823.232.8-5.7-5.5-5.5-5.5-5.0-5.0-5.0-5.1-4.5-3.83.72.5
Pavlov. Cond. magazine entry number6.27.711.63.43.13.33.03.03.02.92.72.43.0-1.5-0.7
Pavlov. Cond. intertrial magazine entries0.40.62.2-0.1-0.5-0.3-0.3-0.5-0.4-0.4-0.8-0.71.11.21.5
Pavlov. Cond. lever-magazine prob. diff.12.616.823.8-4.9-4.7-4.7-4.6-4.4-4.5-4.3-4.2-3.7-3.43.01.8
Pavlov. Cond. response bias17.824.233.9-5.8-5.5-5.6-5.5-5.1-5.2-5.2-5.1-4.7-4.03.72.6
Time in closed arm before self-admin0.40.52.9-0.9-0.4-0.7-0.5-0.6-0.6-0.6-0.2-0.6-1.7-0.2-0.1
Time in closed arm after self-admin1.21.31.91.11.41.41.31.11.11.11.41.10.3-1.2-0.7
Time in open arm before self-admin1.92.13.01.71.51.51.71.41.41.41.41.61.3-1.1-1.3
Time in open arm after self-admin1.11.22.1-0.9-1.2-1.1-1.3-1.0-1.0-1.0-1.3-1.10.21.41.2
Bone: periosteal estimation1.83.85.8-1.7-2.0-1.8-2.2-1.9-1.7-1.9-2.2-2.20.12.42.4
Bone: periosteal perimeter2.64.47.1-1.9-2.1-1.9-2.2-2.0-1.9-2.0-2.3-2.4-0.32.52.7
Bone: post-yield work0.71.01.8-0.7-0.8-0.7-1.1-0.9-1.0-1.1-0.9-1.3-0.01.21.3
Progressive ratio test 1 active lever presses0.30.40.70.50.60.60.50.60.60.60.70.6-0.3-0.8-0.9
Progressive ratio test 1 breakpoint0.30.40.70.50.60.60.50.60.60.60.70.6-0.3-0.8-0.8
Progressive ratio test 1 inactive lever presses0.40.50.70.60.70.80.60.80.80.80.70.80.1-0.7-0.7
Progressive ratio test 2 active lever presses0.40.50.7-0.8-0.8-0.7-0.8-0.7-0.8-0.7-0.7-0.7-0.50.60.3
Progressive ratio test 2 breakpoint0.40.50.7-0.8-0.7-0.7-0.8-0.7-0.8-0.7-0.7-0.7-0.60.50.3
Progressive ratio test 2 inactive lever presses0.10.10.3-0.4-0.3-0.3-0.5-0.2-0.2-0.2-0.3-0.2-0.50.10.2
Incentive Sensitization - Responses1.21.72.2-1.4-1.5-1.4-1.5-1.4-1.4-1.4-1.4-1.3-0.71.20.9
Incentive Sensitization - Breakpoint1.21.62.0-1.4-1.4-1.3-1.4-1.3-1.3-1.3-1.3-1.2-0.81.10.9
Sum of active levers in priming session hrs 5-60.10.10.3-0.10.00.00.30.10.20.10.10.4-0.5-0.4-0.3
Progressive ratio0.10.21.2-0.6-0.4-0.4-0.4-0.2-0.2-0.4-0.2-0.3-1.10.0-0.2
Food seeking constrained by brief footshock2.02.43.3-1.7-1.8-1.8-1.7-1.6-1.7-1.5-1.8-1.5-0.41.51.2
Seeking ratio, punishment vs. effort0.91.31.9-0.8-1.2-1.1-1.1-1.2-1.2-0.9-1.3-1.00.81.41.3
Retroperitoneal fat weight0.83.621.72.11.01.61.11.61.61.60.21.04.71.01.5
Reaction time number correct0.20.31.7-0.10.30.10.40.20.30.20.60.3-1.3-0.9-0.8
Reaction time mean minus median0.82.02.9-1.3-1.4-1.4-1.7-1.4-1.5-1.4-1.5-1.5-0.21.51.3
Reaction time mean minus median AUC0.71.72.6-1.4-1.3-1.4-1.6-1.2-1.4-1.3-1.3-1.4-0.81.11.1
Reaction time num false alarms1.21.72.71.51.21.41.41.61.61.41.01.11.6-0.5-0.2
Reaction time num false alarms AUC0.81.21.91.21.11.21.21.31.41.20.91.01.2-0.6-0.4
Reaction time trials correct on left0.20.31.7-0.10.30.10.40.20.30.20.60.3-1.3-0.9-0.8
Reaction time trials on left0.20.41.7-0.10.30.10.40.20.30.20.60.3-1.3-0.9-0.9
Reaction time mean0.30.53.00.80.50.60.20.70.70.80.30.61.70.00.2
Reaction time mean AUC0.71.12.91.21.01.10.71.21.11.20.71.01.7-0.4-0.1
Median of all reaction times1.01.43.81.31.11.20.81.31.31.40.81.22.0-0.5-0.2
Reaction time omissions0.00.10.4-0.0-0.3-0.1-0.20.10.00.0-0.30.10.70.30.1
Reaction time false alarm rate0.91.33.11.31.01.21.11.31.41.20.81.01.7-0.3-0.1
Reaction time premature initiation rate3.54.87.5-1.8-2.3-2.0-2.3-2.2-2.0-2.1-2.6-2.30.62.72.6
Reaction time premature initiations1.93.44.3-1.8-2.0-1.9-2.0-1.9-1.7-1.9-2.1-2.0-0.32.01.8
Std. dev. reaction times0.61.11.9-0.7-1.0-0.9-1.2-0.8-0.9-0.9-1.2-1.01.01.41.3
Reaction time trials completed0.20.41.7-0.10.30.10.40.20.30.20.60.3-1.3-0.9-0.9
Reaction time trials AUC0.10.31.4-0.10.2-0.00.30.20.20.20.40.2-1.2-0.8-0.7
Run reversals in cocaine runway, females1.21.25.70.1-0.5-0.2-0.5-0.3-0.4-0.5-1.0-0.82.41.71.8
Run reversals in cocaine runway, males0.00.00.30.20.30.20.10.0-0.10.00.20.00.60.00.1
Latency to leave start box in cocaine runway2.32.73.51.91.51.51.81.71.81.71.41.81.8-1.1-1.5
Latency to leave start box in cocaine runway, F1.61.84.01.71.21.21.51.31.41.41.01.52.0-0.5-0.9
Latency to leave start box in cocaine runway, M0.70.71.00.70.80.70.80.90.80.80.90.90.2-0.9-1.0
Std. dev. time between licks in bursts1.82.54.2-1.3-1.7-1.5-1.3-1.6-1.8-1.6-1.9-1.50.12.01.8
Total sessions with >9 infusions1.72.12.8-1.7-1.6-1.7-1.5-1.6-1.6-1.6-1.4-1.5-1.41.10.6
Short access day 1 total inactive lever presses0.00.00.10.20.20.20.20.20.20.20.20.30.2-0.1-0.1
Short access day 10 total inactive lever presses0.61.52.01.31.41.41.31.31.31.31.31.40.6-1.1-0.8
Short access day 1 total infusions2.73.64.5-2.1-2.1-2.1-2.0-2.0-2.0-2.0-2.0-1.9-1.21.71.2
Short access day 10 total infusions0.81.11.5-1.2-1.2-1.2-1.1-1.0-1.0-1.0-1.1-1.1-0.80.80.6
Short access total infusions1.41.82.4-1.6-1.5-1.6-1.4-1.4-1.4-1.4-1.3-1.3-1.31.00.5
Short access day 1 locomotion1.72.13.5-1.8-1.5-1.7-1.6-1.5-1.6-1.6-1.2-1.3-1.90.6-0.0
Short access day 10 total locomotion1.01.82.3-1.5-1.4-1.5-1.3-1.5-1.5-1.5-1.2-1.4-1.40.90.7
Short access total locomotion0.50.71.5-0.9-0.7-1.0-0.8-0.8-0.9-0.9-0.6-0.8-1.20.3-0.1
One hour access (0.3 mA shock)1.01.11.6-1.3-1.1-1.2-1.2-1.1-1.1-1.1-1.0-1.1-1.20.60.6
Compulsive drug intake1.01.12.40.71.00.70.90.91.01.01.21.1-0.8-1.6-1.5
One hour access (shock baseline)1.11.72.2-1.5-1.3-1.4-1.3-1.4-1.4-1.4-1.2-1.3-1.30.90.8
Social response proportion0.50.51.40.80.70.80.70.80.80.80.50.61.2-0.20.1
Social responses0.30.42.20.70.30.50.40.40.40.40.10.21.50.40.7
Social time4.35.87.62.42.52.42.42.82.62.62.52.71.2-2.4-2.1
Soleus weight0.51.55.70.0-0.6-0.2-0.7-0.3-0.3-0.3-1.2-0.82.32.02.4
Bone: stiffness0.10.21.10.50.40.50.10.50.60.40.20.31.00.10.2
Tibialis anterior weight0.20.71.6-0.6-0.9-0.6-0.8-0.6-0.7-0.6-1.1-0.60.51.31.2
Time to tail flick, vehicle, before self-admin0.50.51.7-0.6-0.5-0.4-0.6-0.6-0.7-0.7-0.6-1.0-0.50.71.3
Time to tail flick, vehicle, after self-admin1.21.52.4-1.4-1.3-1.3-1.5-1.2-1.2-1.3-1.2-1.4-0.91.01.0
Time to tail flick, test, before self-admin1.01.02.0-0.6-0.9-0.8-0.9-0.9-1.0-0.9-1.1-1.10.81.41.3
Time to tail flick, test, after self-admin0.30.30.7-0.2-0.5-0.3-0.4-0.5-0.5-0.5-0.6-0.40.40.80.8
Delta time to tail flick, vehicle, before/after SA0.50.51.0-0.8-0.8-1.0-0.9-0.7-0.7-0.7-0.6-0.3-0.60.2-0.7
Delta time to tail flick, test, before/after SA0.80.81.40.80.80.91.00.90.90.90.91.2-0.1-1.0-1.0
Tibia length0.92.57.5-2.1-1.6-1.8-1.9-1.5-1.5-1.5-1.2-0.9-2.70.1-0.4
Ambulatory time before self-admin0.71.11.51.11.11.21.11.01.01.11.11.20.6-1.0-1.0
Ambulatory time after self-admin2.53.05.21.31.81.51.71.71.71.72.01.8-0.6-2.3-2.0
Bone: tissue strength0.80.82.20.60.90.70.50.70.70.71.10.9-0.5-1.4-1.5
Total heroin consumption0.00.00.10.00.0-0.10.3-0.00.1-0.10.10.00.1-0.0-0.1
Bone: trabecular number0.50.81.61.11.21.20.71.01.01.01.00.30.6-0.50.3
Bone: trabecular spacing0.50.61.5-0.9-0.8-1.0-0.6-0.8-0.8-0.8-0.5-0.3-1.2-0.1-0.8
Bone: trabecular thickness0.20.31.10.50.40.60.20.40.40.30.1-0.01.00.51.1
Bone: trabecular tissue density1.01.45.01.41.01.21.11.21.11.10.81.12.2-0.3-0.3
Water consumed over 24 hours0.50.61.31.01.01.11.00.70.70.80.80.60.6-0.30.2
Number of responses in last shaping day0.30.32.00.50.10.30.20.10.10.1-0.2-0.21.40.71.1