Hub : Traits

Short access day 1 locomotion

Tags: Behavior · Cocaine · Short access

Project: p50_paul_meyer_2020

5 loci · 5 genes with independent associations · 5 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr4	176059677	177381574	1	1	1.26e-07	1.28e-01	3.90e-09	Slco1a1
2	chr7	92127461	93066096	1	1	9.85e-13	5.60e-01	1.00e+00	Ndufb9
3	chr9	83390749	84777604	1	1	0.00e+00	5.45e-02	1.00e+00	Retreg2
4	chr17	61510864	62906219	1	1	3.29e-21	9.80e-04	5.10e-04	Ccny
5	chr20	43987022	45386226	1	1	1.60e-08	5.06e-01	1.19e-08	LOC134483824

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	1284.72	3	2	40	0	1.00e+00	Ndufb9 Retreg2 Slco1a1
BMI without tail	48012.24	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Body weight	6.91	3	1	20	0	1.00e+00	Ndufb9 Retreg2 Slco1a1
Epididymis fat weight	36170.21	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Glucose	1186.24	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Heart weight	4511.78	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Left kidney weight	47089.07	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Right kidney weight	38957.32	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Tail length	46066.56	2	2	40	0	1.00e+00	Ccny Retreg2
Length with tail	3073.86	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Length without tail	32334.99	4	2	40	-1	8.71e-04	Ccny Ndufb9 Retreg2 Slco1a1
Liver weight, left	4845.91	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Liver weight, right	67.94	4	1	20	-1	1.70e-04	Ccny LOC134483824 Ndufb9 Retreg2
Parametrial fat weight	210.72	3	1	20	0	1.00e+00	Ccny LOC134483824 Retreg2
Retroperitoneal fat weight	16055.76	1	1	20	0	1.00e+00	Retreg2
Intraocular pressure	40071.91	1	1	20	0	1.00e+00	Retreg2
Extensor digitorum longus weight	4682.69	1	1	20	0	1.00e+00	Retreg2
Soleus weight	31.34	4	1	20	0.94	5.77e-02	Ccny Ndufb9 Retreg2 Slco1a1
Tibialis anterior weight	4881.94	1	1	20	0	1.00e+00	Retreg2
Tibia length	1631.46	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Number of licking bursts	52375.44	3	1	20	0	1.00e+00	Ccny LOC134483824 Retreg2
Food consumed during 24 hour testing period	53104.21	2	1	20	0	1.00e+00	Ccny Retreg2
Times rat made contact with spout	110.75	3	1	20	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Mean time between licks in bursts	66503.89	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Mean num. licks in bursts	71302.54	2	1	20	0	1.00e+00	Ccny Retreg2
Std. dev. time between licks in bursts	94042.02	1	1	20	0	1.00e+00	Retreg2
Water consumed over 24 hours	34475.19	3	1	20	0	1.00e+00	Ccny LOC134483824 Retreg2
Patch foraging indifference point 0 sec	115003.89	1	1	20	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	44399.08	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Indifference point function ln k	47369.79	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Indifference point function log k	47369.79	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Patch foraging total patch changes 0 sec	120264.14	1	1	20	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	2764.09	4	3	60	1	3.40e-03	Ccny LOC134483824 Ndufb9 Retreg2
Patch foraging total patch changes 18 sec	39261.17	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Patch foraging total patch changes 24 sec	41790.01	4	3	60	1	1.34e-04	Ccny LOC134483824 Ndufb9 Retreg2
Patch foraging total patch changes 6 sec	10907.3	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Patch foraging time to switch 0 sec	78314.79	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 0 sec	74407.03	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 12 sec	80953.12	2	2	40	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 18 sec	34430	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Patch foraging water rate 24 sec	2357.13	2	2	40	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 6 sec	1363.06	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Locomotor activity	35.04	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotor testing distance	22392.41	4	2	40	-1	6.78e-04	Ccny Ndufb9 Retreg2 Slco1a1
Locomotor testing rearing	50806.43	3	1	20	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Light reinforcement 1	77669.42	2	2	40	0	1.00e+00	Ccny Retreg2
Light reinforcement 2	36014.89	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time number correct	38376.89	4	3	60	-1	1.38e-04	Ccny LOC134483824 Ndufb9 Retreg2
Reaction time mean minus median	68605.03	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Reaction time mean minus median AUC	104201.41	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Reaction time num false alarms	19041.33	3	2	40	0	1.00e+00	Ccny LOC134483824 Retreg2
Reaction time num false alarms AUC	35512.37	3	2	40	0	1.00e+00	Ccny LOC134483824 Retreg2
Reaction time trials correct on left	38376.89	4	3	60	-1	1.38e-04	Ccny LOC134483824 Ndufb9 Retreg2
Reaction time trials on left	37510.71	4	3	60	-1	1.74e-04	Ccny LOC134483824 Ndufb9 Retreg2
Reaction time mean	47192.43	2	1	20	0	1.00e+00	Ccny Retreg2
Reaction time mean AUC	56674.13	2	1	20	0	1.00e+00	Ccny Retreg2
Median of all reaction times	31417.12	1	1	20	0	1.00e+00	Retreg2
Reaction time omissions	11428.15	3	1	20	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Reaction time false alarm rate	304.41	3	1	20	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Reaction time premature initiation rate	18442.81	2	1	20	0	1.00e+00	Ccny Retreg2
Reaction time premature initiations	69362.16	2	1	20	0	1.00e+00	Ccny Retreg2
Std. dev. reaction times	49830.88	3	1	20	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Reaction time trials completed	37510.71	4	3	60	-1	1.74e-04	Ccny LOC134483824 Ndufb9 Retreg2
Reaction time trials AUC	37936.95	4	2	40	-1	1.84e-04	Ccny LOC134483824 Ndufb9 Retreg2
Social response proportion	35302.65	1	1	20	0	1.00e+00	Retreg2
Social responses	1906.34	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Social time	22121.54	2	1	20	0	1.00e+00	Ccny Retreg2
Conditioned locomotion	3044.63	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. corrected	32913.12	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. not corrected	32126.2	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response before conditioning	1409.02	2	1	20	0	1.00e+00	Ccny Retreg2
Saline control response	12962.78	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	53410.48	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	45793.79	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active responses	9691.24	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	21056.03	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever presses	7939.8	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. lever reinforcers received	2000.77	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	10912.53	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	24714.14	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. change in total contacts	57393.18	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. index score	23998.4	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. latency score	29242.48	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever contacts	22069.78	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	16773.11	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	104933.78	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	22438.69	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. response bias	5169.79	1	1	20	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	63842.12	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Conditioned reinforcement - inactives	51691.77	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Conditioned locomotion	10385.67	4	3	60	1	2.79e-04	Ccny LOC134483824 Ndufb9 Retreg2
Intermittent access intake day 1-15 change	105306.64	2	2	40	0	1.00e+00	Ccny Retreg2
Intermittent access intake escalation	209543.53	1	1	20	0	1.00e+00	Retreg2
Intermittent access intake escalation 2	54050.4	2	2	40	0	1.00e+00	Ccny Retreg2
Intermitt. access day 1 inactive lever presses	78848.66	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Intermitt. access day 15 inactive lever presses	69430.96	3	2	40	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Intermitt. access escalation Index	61669.47	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Intermittent access day 1 total infusions	51844.75	3	1	20	0	1.00e+00	Ccny Retreg2 Slco1a1
Intermittent access day 15 total infusions	65747.49	2	1	20	0	1.00e+00	Ccny Retreg2
Intermittent access terminal intake (last 3 days)	41604.86	2	1	20	0	1.00e+00	Ccny Retreg2
Intermittent access total infusions	233.33	3	1	20	0	1.00e+00	Ccny LOC134483824 Retreg2
Intermittent access day 1 locomotion	34834.34	3	2	40	0	1.00e+00	Ccny Retreg2 Slco1a1
Intermittent access day 15 total locomotion	88947.95	2	2	40	0	1.00e+00	Ccny Retreg2
Intermittent access total locomotion	361.66	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Intermittent access standard deviation	67320.47	3	2	40	0	1.00e+00	Ccny Retreg2 Slco1a1
Cocaine induced anxiety	53447.41	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Post-drug Anxiety	10242.99	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Baseline Anxiety	34558.77	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Lifetime Intake	2294.74	3	2	40	0	1.00e+00	Ccny LOC134483824 Retreg2
Incentive Sensitization - Responses	54538.05	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Incentive Sensitization - Breakpoint	47607.85	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio test 1 active lever presses	19992.63	5	2	40	1	5.68e-07	Ccny LOC134483824 Ndufb9 Retreg2 Slco1a1
Progressive ratio test 1 breakpoint	19267.93	5	2	40	1	3.02e-07	Ccny LOC134483824 Ndufb9 Retreg2 Slco1a1
Progressive ratio test 1 inactive lever presses	30229.49	5	4	80	1	2.09e-06	Ccny LOC134483824 Ndufb9 Retreg2 Slco1a1
Progressive ratio test 2 active lever presses	19090.97	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio test 2 breakpoint	11681.84	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio test 2 inactive lever presses	41031.92	4	2	40	1	2.79e-04	Ccny Ndufb9 Retreg2 Slco1a1
Total sessions with >9 infusions	2017.61	4	2	40	-0.99	1.07e-02	Ccny LOC134483824 Retreg2 Slco1a1
Short access day 1 total inactive lever presses	28608.12	4	3	60	-1	1.13e-04	Ccny LOC134483824 Ndufb9 Retreg2
Short access day 10 total inactive lever presses	108624.06	2	2	40	0	1.00e+00	Ccny Retreg2
Short access day 1 total infusions	27939.77	4	3	60	-1	2.87e-03	Ccny LOC134483824 Retreg2 Slco1a1
Short access day 10 total infusions	19082.3	4	2	40	-1	2.69e-05	Ccny LOC134483824 Ndufb9 Retreg2
Short access total infusions	11356.64	3	2	40	0	1.00e+00	Ccny LOC134483824 Retreg2
Short access day 10 total locomotion	60537.05	3	2	40	0	1.00e+00	Ccny LOC134483824 Retreg2
Short access total locomotion	17071.32	4	1	20	1	7.22e-05	LOC134483824 Ndufb9 Retreg2 Slco1a1
Compulsive drug intake	16367.62	4	1	20	-1	1.65e-04	Ccny LOC134483824 Ndufb9 Retreg2
One hour access (0.3 mA shock)	2436.65	4	3	60	1	2.17e-03	Ccny Ndufb9 Retreg2 Slco1a1
One hour access (shock baseline)	35069.83	4	1	20	1	6.25e-04	Ccny LOC134483824 Retreg2 Slco1a1
Number of responses in last shaping day	12856.63	4	2	40	1	2.38e-03	Ccny LOC134483824 Retreg2 Slco1a1
Context. condit. distance diff. score	488.1	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 1	7315.11	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Locomotion distance, session 1	2213.01	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 2	9358	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 2	1206.44	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 3	2332.53	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	5866.4	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	12131.92	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 7	659.42	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Locomotion distance, session 7	1254.99	3	1	20	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Stereotopy head waving bouts, day 7	5257.18	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving duration, day 7	4446.48	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Locomotion velocity, session 8	950.4	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion distance, session 8	339.03	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Degree of sensitization distance	15309.16	1	1	20	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	4256.13	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active minus inactive responses	1379.85	3	1	20	0	1.00e+00	Ccny LOC134483824 Retreg2
Condit. Reinf. active-inactive response ratio	1097.66	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active responses	5839.15	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. inactive responses	9694.1	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Incentive salience index mean	4933.87	3	1	20	0	1.00e+00	Ccny LOC134483824 Retreg2
Condit. Reinf. lever presses	10719.24	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Time in familiar zone, hab. session 1	41873.03	1	1	20	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	35522.88	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	916.07	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 1	849.35	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 1	571.33	2	1	20	0	1.00e+00	Ccny Retreg2
Time in familiar zone, hab. session 2	23379.25	1	1	20	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	24924.95	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	143.96	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 2	51.92	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 2	77.91	2	1	20	0	1.00e+00	Ccny Retreg2
Novel to familiar place preference ratio	27759.88	2	1	20	0	1.00e+00	Ccny Retreg2
Novelty place preference	27195.73	2	1	20	0	1.00e+00	Ccny Retreg2
Time in novel zone, NPP test	40844.77	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, NPP test	4127.68	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, NPP test	3566.83	2	2	40	0	1.00e+00	Ccny Retreg2
Locomotion velocity, NPP test	2031.76	2	2	40	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever latency	1100.5	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. magazine entry latency	8.04	1	0	0	0	1.00e+00	Ccny
Pavlov. Cond. change in total contacts	2273.55	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. index score	1769.33	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	1841.19	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	1520.48	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. magazine entry number	1086.53	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. intertrial magazine entries	269.44	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	1940.27	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	2606.99	1	1	20	0	1.00e+00	Retreg2
Bone: apparent density	11138.75	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone surface	25125.6	1	1	20	0	1.00e+00	Retreg2
Bone volume	33831.7	1	1	20	0	1.00e+00	Retreg2
Bone: connectivity density	3557.17	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical apparent density	11324.81	4	2	40	-1	1.55e-04	Ccny LOC134483824 Ndufb9 Retreg2
Bone: cortical area	9468.26	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	618.76	3	1	20	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Bone: cortical porosity	1607.52	3	1	20	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Bone: cortical thickness	546.4	3	1	20	0	1.00e+00	LOC134483824 Ndufb9 Retreg2
Bone: cortical thickness	6100.69	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical tissue density	12121.63	4	2	40	-1	1.35e-04	Ccny LOC134483824 Ndufb9 Retreg2
Bone: elastic displacement	29626.25	1	1	20	0	1.00e+00	Retreg2
Bone: elastic work	1494.59	1	1	20	0	1.00e+00	Retreg2
Bone: endosteal estimation	17631.97	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: endosteal perimeter	44697.39	1	1	20	0	1.00e+00	Retreg2
Bone: final force	7031.22	1	1	20	0	1.00e+00	Retreg2
Bone: final moment	1042.62	1	1	20	0	1.00e+00	Retreg2
Bone: marrow area	18537.3	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum diameter	12203.48	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum force	34553.99	1	1	20	0	1.00e+00	Retreg2
Bone: maximum moment	12359.57	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: minimum diameter	8601.34	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Bone: periosteal estimation	38190.5	1	1	20	0	1.00e+00	Retreg2
Bone: periosteal perimeter	21593.51	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Bone: post-yield work	50847.58	1	1	20	0	1.00e+00	Retreg2
Bone: stiffness	35564.91	1	1	20	0	1.00e+00	Retreg2
Bone: tissue strength	12264.67	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular number	20584.56	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular spacing	15655.12	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular thickness	33264.33	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular tissue density	17885.93	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Breakpoint value in progressive ratio session	37486.67	3	2	40	0	1.00e+00	Ccny LOC134483824 Retreg2
Distance traveled before self-admin	44694.41	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Distance traveled after self-admin	50469.31	2	2	40	0	1.00e+00	Ccny Retreg2
Delta time in closed arm before/after self-admin	519.13	4	2	40	0.86	1.44e-01	Ccny LOC134483824 Ndufb9 Retreg2
Delta time in open arm before/after self-admin	27441.91	2	2	40	0	1.00e+00	Ccny Retreg2
Diff in mean of infusions in LGA sessions	54247.61	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Extinction: sum of active levers before priming	22948.06	4	3	60	1	6.28e-04	Ccny LOC134483824 Ndufb9 Retreg2
Active lever presses in extinction session 6	1117.83	3	2	40	0	1.00e+00	Ccny LOC134483824 Retreg2
Delta distance traveled before/after self-admin	4205.11	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Delta ambulatory time before/after self-admin	32036.91	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Time in closed arm before self-admin	22074.57	4	2	40	-1	1.67e-03	Ccny LOC134483824 Retreg2 Slco1a1
Time in closed arm after self-admin	9901.19	2	2	40	0	1.00e+00	Ccny Retreg2
Time in open arm before self-admin	11597.83	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Time in open arm after self-admin	669.46	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Sum of active levers in priming session hrs 5-6	1945.79	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Time to tail flick, vehicle, before self-admin	12970.36	4	2	40	0.99	5.41e-03	Ccny Ndufb9 Retreg2 Slco1a1
Time to tail flick, vehicle, after self-admin	39443.57	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Time to tail flick, test, before self-admin	10954.71	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Time to tail flick, test, after self-admin	2022.59	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Delta time to tail flick, vehicle, before/after SA	12304.47	3	2	40	0	1.00e+00	Ccny Retreg2 Slco1a1
Delta time to tail flick, test, before/after SA	18952.76	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Ambulatory time before self-admin	85572.63	2	2	40	0	1.00e+00	Ccny Retreg2
Ambulatory time after self-admin	44153.3	2	2	40	0	1.00e+00	Ccny Retreg2
Total heroin consumption	369.99	3	2	40	0	1.00e+00	Ccny LOC134483824 Retreg2
Area under the delay curve	40810.48	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 0s delay	3163.48	3	1	20	0	1.00e+00	Ccny LOC134483824 Retreg2
Delay disc. indifference point, 16s delay	37437.33	2	2	40	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 2s delay	416.46	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 24s delay	50025	2	2	40	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 4s delay	870.6	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Delay disc. indifference point, 8s delay	101423.99	1	1	20	0	1.00e+00	Retreg2
Delay discount exponential model param	30110.07	2	1	20	0	1.00e+00	Ccny Retreg2
Delay discount hyperbolic model param	45715.54	1	1	20	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	75084.64	2	1	20	0	1.00e+00	Ccny Retreg2
Change in fecal boli incidents, locomotor task	7889.79	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Time >=10cm from walls, locomotor time 1	12331.1	4	2	40	-1	9.17e-05	Ccny Ndufb9 Retreg2 Slco1a1
Bouts of movement, locomotor time 1	13896.68	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Total resting periods, locomotor time 1	5936.78	2	2	40	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 1	25327.02	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Distance moved, locomotor task time 1	53112.82	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Vertical activity count, locomotor time 1	219061.96	1	1	20	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	80995.71	2	1	20	0	1.00e+00	Ccny Retreg2
Bouts of movement, locomotor time 2	87164.71	2	2	40	0	1.00e+00	Ccny Retreg2
Total resting periods, locomotor time 2	95051.56	2	2	40	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 2	27936.17	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Distance moved, locomotor task time 2	17217.33	2	2	40	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 2	69238.05	2	2	40	0	1.00e+00	Ccny Retreg2
Weight adjusted by age	54026.61	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Seeking ratio, delayed vs. immediate footshock	24709.08	2	2	40	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber	5467.09	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Locomotion in novel chamber post-restriction	51551.01	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Progressive ratio	39494.38	4	3	60	-1	5.65e-04	Ccny LOC134483824 Ndufb9 Retreg2
Food seeking constrained by brief footshock	3673.46	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, punishment vs. effort	39437.56	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Run reversals in cocaine runway, females	18598.36	2	1	20	0	1.00e+00	Ccny Retreg2
Run reversals in cocaine runway, males	9993.2	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Latency to leave start box in cocaine runway	29317.55	2	2	40	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway, F	14201.52	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Latency to leave start box in cocaine runway, M	2456.15	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Cd content in liver	10.06	1	0	0	0	1.00e+00	LOC134483824
Co content in liver	2367.39	2	1	20	0	1.00e+00	LOC134483824 Retreg2
Cu content in liver	89.33	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Fe content in liver	2831.62	2	1	20	0	1.00e+00	LOC134483824 Retreg2
K content in liver	6593.53	1	1	20	0	1.00e+00	Retreg2
Mg content in liver	24493.99	1	1	20	0	1.00e+00	Retreg2
Mn content in liver	2219.37	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Na content in liver	8325.4	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Rb content in liver	241.33	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Se content in liver	8.64	1	0	0	0	1.00e+00	Ndufb9
Sr content in liver	8.84	1	0	0	0	1.00e+00	LOC134483824
Zn content in liver	5264.34	3	2	40	0	1.00e+00	LOC134483824 Ndufb9 Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.08
Adipose	alternative TSS	0	0	1.15
Adipose	gene expression	1	0	1.16
Adipose	isoform ratio	0	0	1.11
Adipose	intron excision ratio	0	0	1.09
Adipose	mRNA stability	1	0	1.17
BLA	alternative polyA	0	0	1.06
BLA	alternative TSS	0	0	1.13
BLA	gene expression	0	0	1.12
BLA	isoform ratio	0	0	1.08
BLA	intron excision ratio	0	0	1.05
BLA	mRNA stability	0	0	1.12
Brain	alternative polyA	0	0	1.11
Brain	alternative TSS	0	0	1.09
Brain	gene expression	0	0	1.14
Brain	isoform ratio	0	0	1.11
Brain	intron excision ratio	0	0	1.04
Brain	mRNA stability	0	0	1.14
Eye	alternative polyA	0	0	0.98
Eye	alternative TSS	0	0	1.01
Eye	gene expression	0	0	1.18
Eye	isoform ratio	0	0	1.2
Eye	intron excision ratio	0	0	1.06
Eye	mRNA stability	0	0	1.06
IC	alternative polyA	0	0	1.07
IC	alternative TSS	0	0	1.19
IC	gene expression	0	0	1.16
IC	isoform ratio	0	0	1.1
IC	intron excision ratio	0	0	1.07
IC	mRNA stability	0	0	1.14
IL	alternative polyA	0	0	1.12
IL	alternative TSS	0	0	1.16
IL	gene expression	0	0	1.11
IL	isoform ratio	0	0	1.1
IL	intron excision ratio	0	0	1.03
IL	mRNA stability	0	0	1.18
LHb	alternative polyA	0	0	1.12
LHb	alternative TSS	0	0	1.19
LHb	gene expression	0	0	1.09
LHb	isoform ratio	0	0	1.12
LHb	intron excision ratio	0	0	1.03
LHb	mRNA stability	0	0	1.21
Liver	alternative polyA	0	0	1.11
Liver	alternative TSS	0	0	1.1
Liver	gene expression	0	0	1.15
Liver	isoform ratio	0	0	1.13
Liver	intron excision ratio	0	0	1.02
Liver	mRNA stability	1	0	1.16
NAcc	alternative polyA	1	0	40.18
NAcc	alternative TSS	0	0	1.15
NAcc	gene expression	0	0	1.14
NAcc	isoform ratio	0	0	1.16
NAcc	intron excision ratio	0	0	1.11
NAcc	mRNA stability	0	0	1.16
OFC	alternative polyA	0	0	1.13
OFC	alternative TSS	0	0	1.14
OFC	gene expression	0	0	1.12
OFC	isoform ratio	0	0	1.06
OFC	intron excision ratio	0	0	1
OFC	mRNA stability	0	0	1.11
PL	alternative polyA	0	0	1.17
PL	alternative TSS	0	0	1.15
PL	gene expression	0	0	1.16
PL	isoform ratio	0	0	1.13
PL	intron excision ratio	0	0	1.11
PL	mRNA stability	0	0	1.17
pVTA	alternative polyA	0	0	1.14
pVTA	alternative TSS	0	0	1.19
pVTA	gene expression	1	0	1.16
pVTA	isoform ratio	0	0	1.14
pVTA	intron excision ratio	0	0	1.06
pVTA	mRNA stability	0	0	1.16
RMTg	alternative polyA	0	0	1.02
RMTg	alternative TSS	0	0	1.09
RMTg	gene expression	0	0	1.14
RMTg	isoform ratio	0	0	1.12
RMTg	intron excision ratio	0	0	1.06
RMTg	mRNA stability	0	0	1.13