Hub : Genes

Fchsd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA alternative TSS XM_063262817.1 0.08 0.05 3.0e-03 0.01 0.03 0.01 0.02 6.5e-02 1.7e-02 9.2e-02 3.4e-02
2 BLA alternative TSS NM_001395742.1 0.09 0.06 3.4e-03 0.02 0.02 0.01 0.02 3.9e-02 3.5e-02 7.4e-02 2.2e-02
3 NAcc mRNA stability Fchsd2 0.02 0.02 3.7e-03 0.01 0.01 0 0 1.5e-02 1.0e-02 5.6e-02 5.0e-02
4 PL gene expression Fchsd2 0.06 0.04 1.3e-04 0.01 0.01 0.02 0.01 4.2e-02 1.2e-02 2.0e-03 7.7e-03
5 Brain mRNA stability Fchsd2 0.12 0.06 5.2e-09 0.09 0.09 0.09 0.09 1.8e-08 1.0e-08 1.9e-08 1.1e-08
6 pVTA gene expression Fchsd2 0.17 0.09 1.2e-08 0.12 0.11 0.11 0.11 9.6e-10 2.7e-09 2.0e-09 2.7e-09
7 IC gene expression Fchsd2 0.16 0.09 4.7e-04 0.09 0.07 0.07 0.07 1.7e-04 6.1e-04 5.8e-04 6.6e-04
8 Adipose gene expression Fchsd2 0.04 0.03 1.5e-03 0.02 0.01 0.02 0.01 2.1e-03 9.2e-03 5.6e-03 6.7e-03
9 Liver alternative TSS NM_001395742.1 0.05 0.04 1.8e-03 0.03 0.01 0.02 0.02 7.0e-04 6.9e-03 2.6e-03 1.9e-03
10 Brain gene expression Fchsd2 0.09 0.05 3.3e-07 0.06 0.06 0.06 0.06 4.2e-06 2.6e-06 4.2e-06 5.2e-06
11 NAcc gene expression Fchsd2 0.07 0.04 9.2e-09 0.04 0.06 0.05 0.05 2.4e-07 4.8e-09 1.1e-07 2.4e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.40.81.4-0.70.70.9-0.80.9-1.0-1.11.2-0.41.00.9
Area under the delay curve0.00.10.2-0.2-0.10.1-0.2-0.10.2-0.20.20.4-0.3-0.4
BMI with tail0.41.23.40.20.3-1.0-0.7-1.31.01.0-0.6-1.2-1.8-1.7
BMI without tail0.52.85.81.3-0.8-2.10.8-2.41.71.8-1.7-0.1-2.3-1.9
Body weight1.46.010.31.2-1.3-2.32.0-2.92.92.9-2.71.5-3.2-3.1
Weight adjusted by age0.20.61.20.5-0.6-0.70.6-0.90.61.1-0.70.7-0.8-0.7
Bone surface0.40.71.81.1-1.4-0.91.2-0.70.40.2-0.31.4-0.2-0.1
Bone volume0.20.41.20.7-1.0-0.60.9-0.50.50.3-0.31.1-0.2-0.2
Breakpoint value in progressive ratio session0.61.11.9-1.31.31.4-0.91.4-0.7-0.80.5-1.10.90.8
Number of licking bursts0.61.76.1-2.52.21.7-1.50.7-0.5-0.50.9-0.8-0.3-0.6
Context. condit. distance diff. score0.60.72.91.7-1.1-1.11.1-0.30.30.2-0.70.20.50.7
Locomotion velocity, session 12.02.33.8-0.91.41.2-1.71.4-1.6-1.61.8-2.01.41.4
Locomotion distance, session 10.40.51.40.8-0.1-0.3-0.20.3-0.5-0.50.7-1.20.81.1
Locomotion velocity, session 20.10.11.20.30.2-0.3-0.3-0.3-0.10.10.1-1.1-0.00.2
Locomotion distance, session 20.20.21.70.6-0.0-0.5-0.2-0.00.20.1-0.0-1.30.20.4
Locomotion velocity, session 30.20.20.80.7-0.3-0.20.30.3-0.2-0.3-0.0-0.10.80.9
Locomotion distance, session 30.50.62.00.7-0.3-0.10.00.5-0.9-0.90.6-0.41.31.4
Stereotopy head waving bouts, day 30.50.61.2-0.3-0.1-0.20.6-0.61.10.8-0.90.8-1.0-1.1
Stereotopy head waving duration, day 30.00.00.10.3-0.2-0.20.20.00.2-0.10.1-0.10.20.2
Locomotion velocity, session 70.70.71.7-0.71.10.7-1.00.8-0.8-0.80.5-1.30.70.7
Locomotion distance, session 70.10.10.3-0.50.50.3-0.50.20.00.1-0.2-0.2-0.2-0.3
Stereotopy head waving bouts, day 71.01.23.51.9-1.8-1.21.5-0.5-0.0-0.3-0.20.80.71.0
Stereotopy head waving duration, day 71.01.34.32.1-1.9-1.51.5-0.80.10.1-0.30.60.40.7
Locomotion velocity, session 80.40.51.31.1-0.8-0.91.1-0.50.50.3-0.80.50.10.2
Locomotion distance, session 80.71.03.81.9-1.1-1.51.1-0.60.80.7-0.9-0.40.10.4
Degree of sensitization distance2.12.35.2-0.2-0.3-0.70.8-1.32.02.0-1.81.0-2.2-2.3
Degree of sensitization stereotypy1.92.16.82.6-2.4-1.71.9-0.80.20.1-0.51.10.71.0
Conditioned locomotion0.20.20.7-0.3-0.00.30.30.60.80.7-0.60.6-0.0-0.2
Cocaine response after cond. corrected0.30.51.8-1.31.00.8-0.90.1-0.1-0.30.3-0.5-0.5-0.7
Cocaine response after cond. not corrected0.40.51.1-0.80.80.6-1.10.3-0.8-1.00.8-0.90.10.1
Cocaine response before conditioning0.91.02.71.2-0.6-0.4-0.20.4-1.3-1.40.9-0.71.41.6
Saline control response2.33.15.92.0-2.1-1.92.4-1.61.61.3-1.72.2-1.0-0.9
Bone: connectivity density1.32.14.1-0.50.80.9-1.41.0-2.0-1.82.0-1.31.61.6
Bone: cortical apparent density0.40.62.5-1.61.31.0-0.60.30.30.3-0.3-0.0-0.6-0.9
Bone: cortical area0.50.81.50.6-0.8-0.91.0-0.91.20.9-1.00.8-1.0-0.9
Bone: cortical porosity0.20.20.70.5-0.30.10.10.6-0.4-0.30.40.30.80.8
Bone: cortical porosity0.30.30.80.6-0.5-0.00.20.5-0.5-0.40.50.40.90.8
Bone: cortical thickness0.30.51.1-0.91.00.8-0.80.7-0.3-0.50.4-1.00.30.3
Bone: cortical thickness0.10.10.30.3-0.4-0.30.4-0.00.60.5-0.40.2-0.1-0.1
Bone: cortical tissue density0.40.62.6-1.61.31.1-0.70.40.20.2-0.2-0.1-0.5-0.7
Condit. Reinf. active minus inactive responses1.31.42.80.7-1.1-1.01.4-1.11.30.9-1.71.4-1.1-1.1
Condit. Reinf. active-inactive response ratio2.02.14.11.1-1.6-1.21.7-1.41.31.2-1.72.0-1.2-1.2
Condit. Reinf. active responses0.60.81.70.3-0.6-0.51.0-0.61.20.8-1.31.0-0.9-0.9
Condit. Reinf. inactive responses0.10.10.3-0.30.50.3-0.40.40.20.00.2-0.60.00.0
Incentive salience index mean0.91.11.80.7-1.0-0.91.2-1.01.21.0-1.41.1-1.0-1.0
Condit. Reinf. lever presses0.10.10.30.5-0.4-0.50.3-0.40.20.2-0.1-0.2-0.2-0.1
Condit. Reinf. active minus inactive responses5.58.414.43.7-3.8-3.53.5-2.92.52.7-2.62.5-1.7-1.4
Condit. Reinf. active-inactive response ratio0.60.92.31.5-1.5-1.31.2-1.00.40.5-0.60.7-0.3-0.1
Condit. Reinf. active responses9.513.720.94.4-4.6-4.44.4-3.73.53.7-3.43.1-2.5-2.1
Condit. Reinf. inactive responses5.98.811.53.2-3.3-3.43.3-2.93.23.4-2.92.3-2.3-2.0
Condit. Reinf. lever presses10.815.732.75.7-5.4-5.24.6-3.93.43.8-3.22.5-1.9-1.4
Condit. Reinf. lever reinforcers received10.114.122.74.7-4.8-4.64.5-3.83.43.7-3.43.1-2.4-1.9
Conditioned reinforcement - actives0.10.31.31.1-0.7-0.50.10.2-0.3-0.30.30.00.70.8
Conditioned reinforcement - inactives0.00.10.2-0.40.50.4-0.30.50.20.1-0.00.40.1-0.1
Conditioned locomotion0.71.03.11.2-0.6-0.3-0.40.8-0.9-0.61.1-0.81.61.7
Patch foraging indifference point 0 sec0.61.85.92.4-2.0-1.91.5-1.10.80.8-0.71.0-0.3-0.0
Patch foraging indifference point AUC0.40.91.50.4-0.9-0.90.7-1.21.01.1-0.90.8-1.2-1.1
Delay disc. indifference point, 0s delay0.91.01.81.3-1.2-1.31.1-1.01.20.7-0.80.6-0.7-0.6
Delay disc. indifference point, 16s delay0.10.21.1-0.3-0.20.40.10.30.2-0.5-0.01.0-0.0-0.2
Delay disc. indifference point, 2s delay1.11.21.71.1-1.3-1.31.2-1.31.11.0-0.81.0-1.0-0.9
Delay disc. indifference point, 24s delay0.30.41.6-1.30.91.0-0.60.8-0.0-0.4-0.10.20.0-0.2
Delay disc. indifference point, 4s delay2.42.63.51.4-1.6-1.71.7-1.81.91.6-1.51.3-1.6-1.5
Delay disc. indifference point, 8s delay0.00.10.2-0.20.10.2-0.50.1-0.1-0.30.40.1-0.0-0.1
Indifference point function ln k0.30.82.30.7-0.20.1-0.01.0-0.9-1.10.7-0.41.51.5
Indifference point function log k0.30.82.30.7-0.20.1-0.01.0-0.9-1.10.7-0.41.51.5
Patch foraging total patch changes 0 sec0.51.65.02.2-1.9-1.81.3-1.10.80.7-0.60.9-0.3-0.1
Patch foraging total patch changes 12 sec1.92.63.51.4-1.6-1.71.5-1.81.81.9-1.61.1-1.7-1.5
Patch foraging total patch changes 18 sec0.71.73.71.9-1.9-1.81.2-1.40.91.2-0.81.0-0.9-0.7
Patch foraging total patch changes 24 sec0.72.53.01.4-1.6-1.71.5-1.71.51.7-1.31.5-1.6-1.5
Patch foraging total patch changes 6 sec0.20.30.90.9-0.8-0.80.4-0.50.50.3-0.30.3-0.3-0.2
Patch foraging time to switch 0 sec0.83.06.9-2.62.42.4-1.91.8-1.3-1.21.3-1.20.90.6
Patch foraging water rate 0 sec0.51.85.32.3-2.0-1.91.5-1.10.90.6-0.90.9-0.3-0.1
Patch foraging water rate 12 sec0.10.62.61.6-0.8-1.10.1-0.20.0-0.1-0.1-1.00.40.7
Patch foraging water rate 18 sec0.61.42.91.7-1.4-1.61.4-1.31.00.8-1.10.4-0.6-0.4
Patch foraging water rate 24 sec0.30.41.20.8-0.1-0.2-0.30.6-0.5-0.80.4-0.71.01.1
Patch foraging water rate 6 sec0.20.31.31.1-0.6-0.70.3-0.1-0.10.00.1-0.60.40.6
Seeking ratio, delayed vs. immediate footshock1.52.23.7-1.51.61.7-1.51.5-1.9-1.31.8-0.71.31.2
Distance traveled before self-admin0.20.41.3-1.11.10.8-0.70.40.00.20.2-0.9-0.1-0.2
Distance traveled after self-admin1.11.93.1-1.01.41.4-1.11.7-1.2-0.91.2-1.81.61.6
Extensor digitorum longus weight0.10.62.0-0.20.0-0.4-0.1-1.10.60.5-0.4-0.0-1.4-1.4
Bone: elastic displacement2.93.75.3-2.02.22.1-2.11.8-1.9-2.31.8-1.91.51.5
Bone: elastic work4.86.39.1-2.22.52.4-2.92.2-2.7-3.02.7-2.62.01.9
Bone: endosteal estimation1.94.66.42.1-2.5-2.32.4-2.41.91.7-1.82.5-1.9-1.8
Bone: endosteal perimeter1.94.86.92.3-2.6-2.52.5-2.52.01.9-1.82.1-1.8-1.6
Epididymis fat weight0.10.41.3-1.11.10.7-0.90.3-0.2-0.20.1-0.5-0.3-0.5
Delta time in closed arm before/after self-admin0.70.62.4-1.00.50.2-0.4-0.60.50.5-0.50.3-1.4-1.5
Delta time in open arm before/after self-admin1.82.14.22.1-2.0-1.81.9-1.41.21.0-1.01.4-0.6-0.4
Diff in mean of infusions in LGA sessions0.61.15.0-2.21.41.8-0.51.0-0.3-0.30.40.40.2-0.1
Delay discount exponential model param0.00.00.10.20.0-0.10.30.1-0.10.2-0.3-0.20.30.3
Extinction: sum of active levers before priming0.10.20.50.3-0.2-0.40.6-0.40.50.2-0.70.1-0.4-0.4
Active lever presses in extinction session 61.41.44.30.50.10.4-0.61.5-0.9-0.91.0-1.12.02.1
Bone: final force0.20.31.5-0.3-0.10.20.40.10.70.6-0.51.2-0.4-0.6
Bone: final moment0.20.31.4-0.1-0.3-0.00.5-0.10.80.6-0.61.2-0.4-0.6
Food consumed during 24 hour testing period0.61.14.52.1-1.7-1.41.1-0.5-0.10.50.30.30.71.0
Glucose0.10.10.3-0.10.30.2-0.20.0-0.6-0.50.5-0.40.30.4
Heart weight0.30.51.41.2-1.2-0.90.9-0.40.40.1-0.30.80.00.1
Delay discount hyperbolic model param0.10.10.30.00.20.20.00.4-0.3-0.1-0.1-0.40.50.5
Intermittent access intake day 1-15 change0.10.72.30.60.4-0.2-0.60.2-0.7-0.90.9-1.50.81.1
Intermittent access intake escalation0.10.71.70.70.2-0.3-0.40.2-0.8-1.01.1-1.30.91.2
Intermittent access intake escalation 20.10.20.50.7-0.3-0.5-0.1-0.2-0.3-0.30.5-0.60.20.3
Intermitt. access day 1 inactive lever presses0.00.41.4-1.21.00.8-0.60.30.1-0.1-0.1-0.2-0.4-0.6
Intermitt. access day 15 inactive lever presses0.10.81.5-1.00.91.2-0.91.2-0.4-0.70.7-0.30.90.8
Intermitt. access escalation Index0.00.00.10.2-0.3-0.20.3-0.2-0.00.0-0.20.3-0.1-0.1
Intermittent access day 1 total infusions0.30.92.41.5-1.6-1.11.2-0.40.50.4-0.41.10.20.3
Intermittent access day 15 total infusions0.20.52.01.4-1.0-0.90.6-0.10.1-0.40.20.20.60.8
Intermittent access terminal intake (last 3 days)0.40.72.81.7-1.4-1.21.0-0.40.50.3-0.20.50.20.4
Intermittent access total infusions0.80.93.11.8-1.4-1.41.0-0.70.70.4-0.40.7-0.10.1
Intermittent access day 1 locomotion0.10.20.60.4-0.6-0.00.30.4-0.1-0.20.20.80.70.7
Intermittent access day 15 total locomotion0.20.92.40.7-0.20.0-0.50.7-0.9-1.11.2-0.71.41.5
Intermittent access total locomotion0.20.31.01.0-0.8-0.50.50.00.0-0.00.20.50.60.7
Intermittent access standard deviation0.10.30.70.30.1-0.60.1-0.60.70.8-0.3-0.6-0.7-0.6
Left kidney weight0.32.34.10.9-1.1-1.51.1-1.91.71.6-1.50.8-2.0-1.9
Right kidney weight0.74.67.21.3-1.7-2.11.7-2.52.22.4-2.11.8-2.7-2.6
Cocaine induced anxiety0.51.33.5-1.91.61.7-1.31.3-0.8-0.50.7-0.20.50.2
Post-drug Anxiety0.50.62.5-1.61.01.3-0.30.7-0.00.0-0.10.7-0.0-0.3
Baseline Anxiety0.81.33.01.0-1.3-1.11.7-1.11.10.6-1.31.5-0.7-0.6
Tail length2.312.317.62.3-3.1-3.24.2-3.93.73.6-3.93.8-3.4-3.3
Length with tail2.611.617.72.1-2.8-2.94.2-3.43.83.6-3.93.9-3.2-3.1
Length without tail0.10.72.2-0.1-0.3-0.21.3-0.51.00.8-0.81.5-0.6-0.7
Times rat made contact with spout0.30.30.7-0.2-0.0-0.20.6-0.70.50.8-0.30.7-0.8-0.8
Lifetime Intake0.91.13.81.9-1.6-1.51.1-0.80.70.4-0.40.7-0.00.2
Liver weight, left0.61.12.60.1-0.5-0.60.7-1.20.81.2-0.81.2-1.5-1.6
Liver weight, right1.22.15.6-0.5-0.1-0.40.8-1.41.61.3-1.51.7-2.2-2.4
Locomotor activity0.20.30.60.8-0.7-0.60.5-0.20.80.4-0.7-0.1-0.1-0.0
Locomotor testing distance1.02.43.41.8-1.8-1.81.7-1.51.81.4-1.60.9-1.1-0.9
Locomotor testing rearing0.82.85.01.2-1.4-1.61.9-1.72.21.8-2.01.4-1.6-1.5
Locomotion in novel chamber0.91.22.5-0.00.30.5-1.61.1-1.2-0.91.4-1.41.11.1
Locomotion in novel chamber post-restriction0.20.62.21.5-1.0-0.80.3-0.1-0.5-0.60.7-0.20.91.0
Fecal boli incidents, locomotor time 10.30.92.70.2-0.10.4-1.31.0-1.1-0.81.6-0.91.00.9
Change in fecal boli incidents, locomotor task0.20.20.7-0.50.30.30.4-0.20.1-0.6-0.80.8-0.3-0.3
Time >=10cm from walls, locomotor time 10.30.41.61.3-1.2-0.70.6-0.00.00.3-0.20.80.30.3
Bouts of movement, locomotor time 10.20.31.20.4-0.6-0.30.6-0.10.80.3-0.11.1-0.1-0.2
Total resting periods, locomotor time 10.10.10.30.1-0.10.2-0.00.50.1-0.30.50.50.60.5
Rest time, locomotor task time 10.30.51.0-0.30.10.7-0.10.9-0.9-0.90.60.61.00.9
Distance moved, locomotor task time 10.20.61.20.3-0.2-0.70.4-1.00.91.1-0.6-0.1-1.1-1.0
Vertical activity count, locomotor time 10.10.91.50.7-0.6-1.00.7-1.01.21.2-1.00.3-1.1-1.0
Time >=10cm from walls, locomotor time 21.23.35.21.8-2.2-1.82.2-1.41.91.5-2.12.3-1.1-1.1
Bouts of movement, locomotor time 20.92.94.80.9-1.4-1.31.6-1.52.01.7-1.92.2-1.9-2.0
Total resting periods, locomotor time 20.41.83.30.5-1.0-0.91.1-1.11.51.3-1.51.8-1.6-1.7
Rest time, locomotor task time 21.11.94.1-2.01.81.8-1.51.3-1.1-1.31.2-0.90.60.5
Distance moved, locomotor task time 22.22.94.72.2-2.0-2.12.0-1.71.71.8-1.51.4-1.0-0.8
Vertical activity count, locomotor time 20.92.02.81.4-1.4-1.51.4-1.31.51.7-1.51.3-1.2-1.2
Light reinforcement 10.62.75.8-2.32.41.9-2.31.2-1.2-1.01.4-1.90.40.3
Light reinforcement 21.12.56.4-0.91.51.0-1.91.1-1.6-1.51.9-2.51.31.5
Bone: marrow area1.74.15.61.9-2.4-2.22.2-2.31.81.7-1.72.4-1.9-1.8
Bone: maximum diameter1.93.85.42.1-2.3-2.22.3-2.01.91.7-1.81.9-1.5-1.3
Bone: maximum force0.10.10.8-0.1-0.20.10.30.10.30.2-0.10.9-0.1-0.3
Bone: maximum moment0.10.10.60.1-0.3-0.10.4-0.10.40.2-0.20.8-0.2-0.3
Mean time between licks in bursts1.911.714.83.0-3.6-3.53.6-3.33.83.8-3.53.2-3.1-3.0
Mean num. licks in bursts0.71.85.62.4-2.1-1.71.7-0.90.70.8-0.91.10.10.3
Cd content in liver0.30.30.7-0.2-0.1-0.10.5-0.60.50.5-0.60.8-0.7-0.8
Co content in liver2.83.34.71.6-2.1-1.82.1-1.71.81.9-1.82.2-1.4-1.4
Cu content in liver2.12.43.31.1-1.4-1.51.6-1.81.51.6-1.61.6-1.7-1.6
Fe content in liver0.00.00.0-0.10.00.10.10.00.00.2-0.00.10.00.0
K content in liver0.40.40.8-0.10.1-0.20.3-0.40.90.9-0.70.1-0.8-0.9
Mg content in liver0.10.10.20.30.0-0.30.0-0.20.20.3-0.2-0.5-0.1-0.1
Mn content in liver2.73.04.2-1.51.91.7-1.91.8-1.7-2.11.8-1.71.51.5
Na content in liver0.20.20.80.9-0.6-0.60.6-0.4-0.1-0.10.1-0.10.30.5
Rb content in liver0.30.30.90.8-0.9-0.60.9-0.50.20.1-0.20.9-0.0-0.0
Se content in liver3.94.67.5-2.72.72.7-2.42.2-2.0-2.21.9-1.51.51.2
Sr content in liver1.00.92.00.00.40.3-0.90.5-1.1-1.41.1-1.40.91.1
Zn content in liver1.72.04.12.0-1.6-2.01.3-1.61.11.4-1.20.3-1.1-0.8
Bone: minimum diameter2.54.86.71.3-1.7-1.92.3-2.42.62.2-2.32.3-2.4-2.4
Time in familiar zone, hab. session 10.20.20.40.2-0.3-0.40.5-0.60.50.4-0.60.3-0.5-0.5
Time in novel zone, hab. session 10.10.10.3-0.60.40.5-0.20.3-0.3-0.1-0.00.40.0-0.1
Total zone transitions, hab. session 10.50.61.7-0.10.40.4-0.20.7-0.8-1.00.8-0.81.21.3
Total locomotion distance, hab. session 11.11.63.7-0.4-0.0-0.40.9-1.11.61.4-1.71.1-1.8-1.9
Locomotion velocity, hab. session 10.91.22.7-0.3-0.0-0.40.7-0.91.51.3-1.40.7-1.6-1.7
Time in familiar zone, hab. session 22.02.33.71.7-1.9-1.61.8-1.31.31.3-1.71.7-1.0-1.0
Time in novel zone, hab. session 21.61.73.9-1.01.51.1-1.71.1-1.2-1.01.4-2.01.01.0
Total zone transitions, hab. session 20.40.51.51.2-0.7-0.70.9-0.00.1-0.2-0.1-0.30.81.1
Total locomotion distance, hab. session 22.83.77.00.6-0.9-1.41.8-1.72.72.4-2.61.4-2.2-2.2
Locomotion velocity, hab. session 23.04.07.70.5-0.8-1.41.9-1.82.82.5-2.61.4-2.4-2.3
Novel to familiar place preference ratio1.01.33.20.4-0.8-0.51.4-0.41.51.4-1.51.8-0.7-0.8
Novelty place preference1.01.32.90.4-0.8-0.51.4-0.41.61.4-1.51.7-0.7-0.8
Time in novel zone, NPP test1.31.53.30.6-0.9-0.71.6-0.41.71.5-1.61.8-0.7-0.9
Total zone transitions, NPP test0.60.82.90.10.50.2-0.70.6-0.8-0.61.3-1.71.01.2
Total locomotion distance, NPP test0.70.92.3-0.40.5-0.4-0.1-0.81.31.3-0.8-0.6-1.5-1.5
Locomotion velocity, NPP test0.50.81.9-0.70.9-0.1-0.4-0.61.01.0-0.6-0.9-1.4-1.3
Intraocular pressure1.42.36.1-0.20.30.9-1.31.0-2.5-1.92.3-0.91.71.7
Delta distance traveled before/after self-admin0.50.61.41.2-1.0-0.51.00.2-0.3-0.0-0.00.61.01.1
Delta ambulatory time before/after self-admin0.30.61.51.1-0.8-0.30.70.4-0.6-0.40.30.31.21.2
Parametrial fat weight0.81.83.8-1.41.61.1-1.90.5-1.4-1.31.7-1.90.40.5
Pavlov. Cond. lever latency0.81.12.3-1.51.51.3-1.21.0-0.8-0.90.7-0.90.50.3
Pavlov. Cond. magazine entry latency2.02.65.92.4-2.2-2.21.8-1.71.31.3-1.41.0-0.8-0.5
Pavlov. Cond. change in total contacts1.31.43.01.6-1.7-1.31.5-1.00.90.7-1.11.5-0.5-0.4
Pavlov. Cond. index score1.72.14.82.2-2.1-2.01.7-1.51.11.1-1.11.0-0.7-0.5
Pavlov. Cond. latency score1.72.14.62.1-2.1-1.91.7-1.41.11.2-1.11.1-0.7-0.5
Pavlov. Cond. lever contacts0.80.92.11.4-1.4-1.31.1-1.00.60.7-0.70.7-0.5-0.3
Pavlov. Cond. magazine entry number2.12.66.0-2.52.32.2-1.91.6-1.1-1.21.3-1.30.70.5
Pavlov. Cond. intertrial magazine entries0.40.51.3-1.11.01.1-0.50.8-0.4-0.90.4-0.20.40.3
Pavlov. Cond. lever-magazine prob. diff.1.31.63.92.0-1.9-1.71.5-1.30.80.9-0.90.9-0.5-0.3
Pavlov. Cond. response bias0.91.12.71.6-1.4-1.51.2-1.10.70.7-0.80.6-0.5-0.3
Pavlov. Cond. lever latency9.813.733.1-5.85.25.1-4.23.6-3.0-3.32.9-1.81.50.8
Pavlov. Cond. magazine entry latency1.01.45.52.3-1.5-1.90.8-0.90.60.8-0.5-1.00.10.5
Pavlov. Cond. change in total contacts4.310.625.65.1-4.4-4.53.9-3.12.62.9-2.71.5-1.1-0.5
Pavlov. Cond. index score5.89.123.74.9-4.2-4.33.3-2.92.52.7-2.31.0-1.1-0.5
Pavlov. Cond. latency score4.67.320.34.5-3.8-3.92.9-2.62.12.4-2.00.6-0.9-0.3
Pavlov. Cond. lever contacts9.413.831.95.6-5.1-5.04.3-3.63.13.4-3.02.0-1.6-0.9
Pavlov. Cond. magazine entry number2.12.810.2-3.22.42.6-1.61.3-0.9-1.10.90.4-0.0-0.5
Pavlov. Cond. intertrial magazine entries1.02.23.70.6-1.2-1.11.6-1.51.41.5-1.61.9-1.6-1.7
Pavlov. Cond. lever-magazine prob. diff.5.99.022.44.7-4.1-4.23.3-2.92.52.8-2.41.0-1.2-0.6
Pavlov. Cond. response bias8.912.331.65.6-4.9-4.93.9-3.32.83.1-2.71.4-1.3-0.6
Time in closed arm before self-admin0.30.51.41.2-0.8-0.50.90.40.3-0.2-0.30.01.01.2
Time in closed arm after self-admin0.70.71.5-1.21.01.2-0.71.2-0.6-1.00.6-0.40.70.5
Time in open arm before self-admin2.63.27.5-2.42.42.0-2.71.2-1.9-1.11.7-1.70.40.2
Time in open arm after self-admin0.30.30.90.5-0.6-0.70.3-1.00.20.6-0.30.4-0.7-0.7
Bone: periosteal estimation1.33.14.11.7-2.0-2.01.9-2.01.71.4-1.41.8-1.6-1.5
Bone: periosteal perimeter1.32.53.71.7-1.8-1.91.7-1.91.61.3-1.31.2-1.5-1.3
Bone: post-yield work0.10.20.30.3-0.4-0.30.5-0.30.40.6-0.40.6-0.3-0.3
Progressive ratio test 1 active lever presses0.20.30.7-0.00.10.4-0.20.6-0.5-0.60.70.20.90.9
Progressive ratio test 1 breakpoint0.20.30.7-0.00.10.4-0.20.5-0.5-0.60.70.20.80.8
Progressive ratio test 1 inactive lever presses0.10.20.6-0.10.30.4-0.30.6-0.5-0.80.50.10.70.6
Progressive ratio test 2 active lever presses0.20.30.80.9-0.8-0.70.6-0.50.2-0.30.00.6-0.00.1
Progressive ratio test 2 breakpoint0.20.30.80.9-0.8-0.70.6-0.50.2-0.30.00.60.00.1
Progressive ratio test 2 inactive lever presses0.10.20.60.5-0.0-0.1-0.10.4-0.1-0.80.3-0.30.60.7
Incentive Sensitization - Responses0.30.71.51.2-1.1-1.21.0-1.00.70.2-0.50.7-0.6-0.5
Incentive Sensitization - Breakpoint0.20.51.21.1-0.9-1.00.8-0.80.6-0.0-0.40.4-0.4-0.3
Sum of active levers in priming session hrs 5-60.10.10.2-0.10.10.20.10.40.30.4-0.2-0.50.30.4
Progressive ratio0.20.61.20.50.1-0.1-0.40.3-0.7-1.10.9-1.10.91.1
Food seeking constrained by brief footshock1.61.93.01.5-1.5-1.71.3-1.71.61.2-1.50.7-1.3-1.1
Seeking ratio, punishment vs. effort1.43.24.81.0-1.3-1.61.6-1.92.02.2-2.11.5-2.0-2.0
Retroperitoneal fat weight0.62.68.1-2.01.50.3-0.4-1.41.41.3-1.20.4-2.7-2.8
Reaction time number correct0.20.61.3-0.20.50.6-0.51.1-0.6-0.70.3-0.71.11.1
Reaction time mean minus median0.21.21.91.1-1.1-1.31.1-1.11.41.2-1.10.9-1.0-0.9
Reaction time mean minus median AUC0.10.81.61.3-1.1-1.11.0-0.61.01.0-0.90.7-0.4-0.4
Reaction time num false alarms0.40.72.4-1.61.10.9-0.50.20.40.5-0.00.3-0.8-1.1
Reaction time num false alarms AUC0.20.41.5-1.20.90.9-0.70.40.10.30.30.0-0.5-0.7
Reaction time trials correct on left0.20.61.3-0.20.50.6-0.51.1-0.6-0.70.3-0.71.11.1
Reaction time trials on left0.20.61.3-0.20.50.6-0.51.1-0.6-0.70.4-0.71.21.1
Reaction time mean0.30.71.8-0.80.30.20.1-0.21.11.0-0.90.6-1.1-1.4
Reaction time mean AUC0.20.41.0-1.00.60.5-0.10.10.70.6-0.70.4-0.7-1.0
Median of all reaction times0.40.61.6-1.30.80.7-0.40.20.70.6-0.60.3-0.8-1.1
Reaction time omissions0.20.30.7-0.10.1-0.20.2-0.50.80.7-0.50.4-0.8-0.9
Reaction time false alarm rate0.40.51.5-1.20.70.6-0.6-0.10.40.60.10.1-1.0-1.2
Reaction time premature initiation rate2.64.06.11.8-2.2-2.21.7-2.52.12.1-1.71.3-2.2-2.0
Reaction time premature initiations0.61.72.81.5-1.6-1.71.1-1.51.41.3-1.10.6-1.2-1.0
Std. dev. reaction times0.72.43.80.7-1.2-1.31.4-1.61.91.7-1.61.6-1.9-1.9
Reaction time trials completed0.20.61.3-0.20.50.6-0.51.1-0.6-0.70.4-0.71.21.1
Reaction time trials AUC0.10.30.8-0.10.30.4-0.40.9-0.4-0.50.1-0.50.90.8
Run reversals in cocaine runway, females2.02.34.90.2-0.6-1.11.1-2.01.61.6-1.80.8-2.2-2.1
Run reversals in cocaine runway, males0.40.41.3-0.40.30.6-0.40.5-0.9-1.10.9-0.30.60.5
Latency to leave start box in cocaine runway0.50.72.8-1.71.11.0-1.0-0.0-0.3-0.70.3-0.3-0.6-0.7
Latency to leave start box in cocaine runway, F0.60.72.2-1.40.50.5-0.2-0.60.60.3-0.60.6-1.4-1.5
Latency to leave start box in cocaine runway, M1.31.22.2-0.81.00.9-1.50.8-1.2-1.31.2-1.50.80.8
Std. dev. time between licks in bursts2.85.47.71.6-2.0-2.22.1-2.42.72.8-2.32.0-2.6-2.6
Total sessions with >9 infusions1.21.44.52.1-1.8-1.71.4-1.10.70.4-0.71.0-0.2-0.0
Short access day 1 total inactive lever presses0.00.10.20.4-0.4-0.40.3-0.20.50.0-0.10.4-0.1-0.2
Short access day 10 total inactive lever presses0.10.41.1-1.10.91.0-0.90.8-0.3-0.40.3-0.20.2-0.0
Short access day 1 total infusions1.83.67.02.6-2.6-2.42.2-1.81.61.5-1.51.6-1.0-0.9
Short access day 10 total infusions0.81.23.51.9-1.7-1.61.4-1.10.70.5-0.60.9-0.2-0.0
Short access total infusions1.01.54.72.2-1.9-1.71.4-1.00.70.4-0.51.0-0.10.1
Short access day 1 locomotion0.40.72.31.5-1.0-0.80.50.0-0.8-0.80.70.21.01.1
Short access day 10 total locomotion0.20.61.91.4-0.9-1.20.9-0.70.60.8-0.50.1-0.20.0
Short access total locomotion0.20.31.00.6-0.3-0.2-0.00.3-0.7-0.70.7-0.20.91.0
One hour access (0.3 mA shock)0.30.41.71.3-0.9-1.00.4-0.40.20.30.20.20.10.3
Compulsive drug intake2.33.44.5-1.51.72.0-1.82.1-2.1-2.12.0-1.41.91.8
One hour access (shock baseline)0.51.34.02.0-1.5-1.81.1-1.11.10.9-0.70.2-0.5-0.2
Social response proportion0.30.41.1-0.50.6-0.0-0.6-0.30.80.6-0.3-0.5-1.0-1.0
Social responses1.31.84.1-0.1-0.0-0.60.6-1.11.91.8-1.41.0-1.9-2.0
Social time1.32.05.1-2.12.31.9-1.61.6-0.6-1.10.9-1.00.80.6
Soleus weight0.82.56.9-0.0-0.4-1.00.6-1.81.81.6-1.50.9-2.5-2.6
Bone: stiffness0.40.72.1-0.6-0.00.20.5-0.21.01.0-0.71.4-1.0-1.2
Tibialis anterior weight0.41.42.30.5-0.8-1.01.1-1.21.51.3-1.21.3-1.5-1.5
Time to tail flick, vehicle, before self-admin0.10.10.30.5-0.1-0.40.5-0.20.30.1-0.10.00.30.4
Time to tail flick, vehicle, after self-admin0.30.62.01.4-1.4-0.90.9-0.40.10.2-0.00.80.20.3
Time to tail flick, test, before self-admin1.72.03.41.2-1.5-1.41.8-1.61.31.4-1.41.7-1.0-0.9
Time to tail flick, test, after self-admin2.52.63.41.0-1.5-1.41.8-1.61.81.6-1.81.7-1.7-1.7
Delta time to tail flick, vehicle, before/after SA0.20.20.70.7-0.9-0.40.1-0.1-0.5-0.20.30.30.20.1
Delta time to tail flick, test, before/after SA0.30.30.7-0.80.80.6-0.80.5-0.3-0.40.3-0.8-0.1-0.2
Tibia length0.41.23.71.9-1.9-1.11.3-0.00.30.8-0.30.80.80.8
Ambulatory time before self-admin0.20.71.7-1.31.21.1-0.90.9-0.3-0.30.5-1.00.30.3
Ambulatory time after self-admin1.01.53.6-0.50.81.1-0.61.7-1.1-1.01.0-1.21.81.9
Bone: tissue strength3.03.23.9-1.11.61.6-1.81.8-1.9-1.91.8-2.01.91.9
Total heroin consumption0.10.10.40.10.1-0.10.40.10.60.4-0.6-0.40.00.1
Bone: trabecular number1.42.63.6-1.61.81.7-1.61.5-1.8-1.71.9-1.31.41.4
Bone: trabecular spacing0.20.31.11.0-0.5-0.8-0.1-0.20.10.20.2-1.10.20.4
Bone: trabecular thickness0.50.72.6-0.6-0.10.30.9-0.10.80.7-1.11.6-0.6-0.8
Bone: trabecular tissue density1.42.45.4-1.00.10.11.0-0.82.01.8-1.82.0-2.0-2.3
Water consumed over 24 hours0.20.30.7-0.70.70.7-0.40.5-0.6-0.40.9-0.20.50.4
Number of responses in last shaping day0.40.51.5-0.3-0.4-0.10.3-0.50.80.6-0.41.2-1.0-1.2