Hub : Genes

Fchsd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA alternative TSS XM_017589187.2 0.08 0.06 1.6e-03 0.01 0.03 0.01 0.02 9.2e-02 9.1e-03 1.3e-01 3.4e-02
2 BLA alternative TSS XM_039113302.1 0.09 0.06 1.4e-03 0.01 0.03 0.01 0.02 9.5e-02 8.4e-03 1.3e-01 3.5e-02
3 BLA isoform ratio XM_039113302.1 0.09 0.07 3.1e-03 0.02 0.03 0.05 0.03 1.9e-02 6.8e-03 1.7e-03 9.9e-03
4 PL gene expression Fchsd2 0.06 0.04 1.6e-05 0.02 0.03 0.03 0.03 1.6e-03 6.3e-04 5.8e-04 4.6e-04
5 Brain mRNA stability Fchsd2 0.09 0.05 2.2e-07 0.05 0.06 0.07 0.06 1.7e-05 1.8e-06 5.1e-07 3.1e-06
6 Adipose gene expression Fchsd2 0.04 0.03 1.6e-03 0.02 0.02 0.02 0.02 1.9e-03 4.5e-03 1.8e-03 1.8e-03
7 PL isoform ratio NM_001395742.1 0.23 0.13 3.3e-03 0 0.01 0.01 0.01 1.0e-01 1.1e-02 1.3e-02 4.0e-02
8 Brain gene expression Fchsd2 0.11 0.05 9.8e-09 0.08 0.08 0.08 0.09 1.1e-07 3.0e-08 1.3e-07 7.2e-09
9 pVTA gene expression Fchsd2 0.12 0.07 1.4e-03 0.08 0.07 0.07 0.07 2.5e-04 4.1e-04 4.1e-04 8.0e-04
10 NAcc gene expression Fchsd2 0.07 0.04 2.9e-07 0.04 0.05 0.05 0.05 1.1e-05 6.1e-07 1.2e-06 2.4e-06
11 Liver isoform ratio NM_001395742.1 0.05 0.04 1.0e-04 0.03 0.03 0.03 0.03 4.4e-04 2.7e-04 2.5e-04 2.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.30.51.00.3-0.30.50.5-0.7-1.0-0.70.9-0.70.8-1.0
Area under the delay curve0.10.10.40.3-0.30.60.10.10.1-0.2-0.10.2-0.50.3
BMI with tail0.20.82.91.0-1.01.11.7-1.0-0.60.90.00.30.7-0.2
BMI without tail0.91.96.1-0.60.5-1.1-0.71.61.0-1.3-1.92.5-1.31.5
Body weight1.14.58.7-0.60.6-1.0-1.72.42.60.1-3.02.9-2.52.9
Weight adjusted by age0.80.91.6-0.80.8-0.9-0.81.20.9-0.8-1.11.3-0.90.9
Bone surface0.61.13.4-1.41.4-1.1-1.31.00.4-1.9-0.40.6-0.4-0.1
Bone volume0.40.61.3-1.11.1-0.8-1.20.80.6-1.0-0.40.4-0.40.0
Breakpoint value in progressive ratio session0.50.51.20.7-0.70.40.7-0.8-0.61.10.8-0.61.0-0.4
Number of licking bursts1.92.26.72.6-2.62.31.5-0.8-0.61.30.3-0.0-0.20.5
Context. condit. distance diff. score1.01.24.8-1.81.8-2.2-0.90.40.3-0.5-0.0-0.30.6-0.4
Locomotion velocity, session 11.51.62.70.8-0.81.01.4-1.6-1.6-0.11.5-1.31.6-1.4
Locomotion distance, session 10.40.51.3-0.70.7-0.50.0-0.5-0.6-0.80.6-0.51.1-1.1
Locomotion velocity, session 20.10.10.4-0.10.10.10.3-0.3-0.2-0.50.00.20.5-0.6
Locomotion distance, session 20.10.10.4-0.40.4-0.20.0-0.30.10.4-0.0-0.10.6-0.6
Locomotion velocity, session 30.40.41.1-0.90.9-1.1-0.6-0.0-0.1-0.20.5-0.90.6-0.7
Locomotion distance, session 30.90.91.9-1.11.0-1.0-0.0-0.4-0.8-1.20.9-0.91.1-1.4
Stereotopy head waving bouts, day 30.50.61.20.3-0.30.1-0.60.71.10.9-0.90.8-1.11.0
Stereotopy head waving duration, day 30.00.10.1-0.20.2-0.3-0.0-0.10.10.30.2-0.20.3-0.3
Locomotion velocity, session 70.40.50.70.6-0.70.40.8-0.9-0.80.60.7-0.70.8-0.6
Locomotion distance, session 70.10.20.80.4-0.40.50.2-0.10.10.9-0.10.1-0.40.4
Stereotopy head waving bouts, day 71.61.84.5-2.01.9-2.1-1.30.70.0-2.10.2-0.10.7-1.1
Stereotopy head waving duration, day 71.82.26.8-2.22.1-2.2-1.30.80.1-2.6-0.10.30.6-1.1
Locomotion velocity, session 80.60.72.2-1.31.3-1.5-1.20.50.5-0.5-0.3-0.20.10.0
Locomotion distance, session 80.81.23.8-1.91.9-1.9-0.90.40.8-0.2-0.50.10.4-0.4
Degree of sensitization distance2.52.55.70.4-0.40.3-0.91.32.01.7-2.01.8-2.12.4
Degree of sensitization stereotypy3.23.58.9-2.82.8-3.0-1.81.00.1-2.70.1-0.00.7-1.2
Conditioned locomotion0.60.75.60.2-0.10.3-0.3-0.10.92.4-0.2-0.7-0.60.6
Cocaine response after cond. corrected0.70.82.31.5-1.51.30.8-0.3-0.20.7-0.20.4-0.40.8
Cocaine response after cond. not corrected0.40.51.11.0-1.01.01.0-0.6-0.8-0.20.4-0.00.4-0.1
Cocaine response before conditioning1.31.63.6-1.21.1-1.00.3-0.6-1.3-1.91.1-0.91.6-1.8
Saline control response2.83.66.3-2.22.2-2.2-2.52.12.0-1.1-1.81.5-1.61.1
Bone: connectivity density1.21.94.00.2-0.30.51.2-1.2-2.0-1.91.6-1.01.7-1.9
Bone: cortical apparent density1.01.33.91.5-1.41.20.10.20.72.0-0.70.4-1.11.6
Bone: cortical area0.91.32.8-0.91.0-0.8-1.51.21.70.2-1.41.0-1.21.1
Bone: cortical porosity0.40.50.9-0.90.9-0.4-0.2-0.2-0.5-0.90.7-0.80.5-0.8
Bone: cortical porosity0.30.40.8-0.90.9-0.4-0.4-0.1-0.4-0.70.6-0.80.4-0.6
Bone: cortical thickness0.20.31.50.6-0.60.70.4-0.50.21.20.0-0.30.2-0.0
Bone: cortical thickness0.10.11.1-0.30.3-0.1-0.2-0.00.51.0-0.1-0.2-0.10.1
Bone: cortical tissue density1.01.34.11.5-1.51.20.20.10.72.0-0.60.3-1.11.6
Condit. Reinf. active minus inactive responses1.11.22.0-0.80.8-1.0-1.41.41.3-0.1-1.20.9-1.31.3
Condit. Reinf. active-inactive response ratio1.71.93.1-1.21.2-1.3-1.71.81.3-0.9-1.31.1-1.61.3
Condit. Reinf. active responses0.50.71.3-0.30.4-0.2-1.00.91.20.5-0.90.6-1.11.0
Condit. Reinf. inactive responses0.20.31.20.4-0.40.90.3-0.50.21.10.0-0.2-0.0-0.0
Incentive salience index mean0.70.91.4-0.70.7-0.5-1.21.11.2-0.3-1.10.9-1.20.9
Condit. Reinf. lever presses0.10.21.1-0.30.30.3-0.10.10.1-1.0-0.30.5-0.1-0.2
Condit. Reinf. active minus inactive responses6.78.313.7-3.73.7-3.6-3.53.12.5-2.6-2.42.4-1.71.2
Condit. Reinf. active-inactive response ratio1.21.33.1-1.61.6-1.5-1.31.00.5-1.8-0.60.8-0.2-0.0
Condit. Reinf. active responses9.112.719.2-4.44.4-4.2-4.33.83.5-2.7-3.33.2-2.41.7
Condit. Reinf. inactive responses5.97.310.2-3.13.1-2.9-3.23.03.2-1.3-2.92.6-2.21.6
Condit. Reinf. lever presses11.014.931.4-5.65.6-5.1-4.43.63.1-3.7-2.92.8-1.50.7
Condit. Reinf. lever reinforcers received9.413.321.7-4.74.7-4.4-4.43.83.4-3.2-3.23.2-2.21.5
Conditioned reinforcement - actives0.60.61.9-1.41.4-0.7-0.4-0.1-0.3-1.00.4-0.40.5-1.0
Conditioned reinforcement - inactives0.20.30.80.2-0.20.5-0.30.20.80.5-0.50.4-0.90.7
Conditioned locomotion0.91.12.8-1.51.4-1.0-0.3-0.4-0.5-0.90.8-0.61.2-1.7
Patch foraging indifference point 0 sec1.22.05.9-2.42.4-1.8-1.21.11.0-1.3-0.70.9-0.2-0.4
Patch foraging indifference point AUC0.70.81.5-0.30.3-0.7-1.01.11.0-0.1-1.21.2-1.10.8
Delay disc. indifference point, 0s delay0.50.51.1-0.90.9-0.7-0.80.61.0-0.2-0.80.7-0.50.3
Delay disc. indifference point, 16s delay0.10.10.60.2-0.20.2-0.10.00.20.80.0-0.5-0.50.3
Delay disc. indifference point, 2s delay1.11.22.1-1.01.0-0.8-1.41.11.1-1.3-1.11.1-1.10.8
Delay disc. indifference point, 24s delay0.80.83.31.2-1.11.00.5-0.50.01.80.2-0.8-0.40.5
Delay disc. indifference point, 4s delay1.61.72.9-1.01.0-0.9-1.41.51.7-0.6-1.51.6-1.41.3
Delay disc. indifference point, 8s delay0.10.10.40.2-0.10.60.4-0.1-0.1-0.30.10.1-0.1-0.0
Indifference point function ln k0.60.82.0-0.80.8-0.40.1-0.8-0.8-0.31.1-1.41.2-1.1
Indifference point function log k0.60.82.0-0.80.8-0.40.1-0.8-0.8-0.31.1-1.41.2-1.1
Patch foraging total patch changes 0 sec1.01.54.5-2.12.1-1.6-0.91.00.9-1.1-0.71.0-0.2-0.4
Patch foraging total patch changes 12 sec1.72.23.5-1.31.3-1.4-1.51.71.9-0.2-1.81.8-1.61.1
Patch foraging total patch changes 18 sec0.91.22.6-1.61.6-1.3-0.91.10.8-1.1-0.91.2-0.6-0.2
Patch foraging total patch changes 24 sec1.72.13.6-1.41.4-1.4-1.61.81.6-0.5-1.61.9-1.51.0
Patch foraging total patch changes 6 sec0.20.20.8-0.80.8-0.9-0.30.30.40.1-0.30.4-0.0-0.4
Patch foraging time to switch 0 sec2.13.36.72.6-2.62.52.1-1.7-1.41.71.4-1.30.6-0.2
Patch foraging water rate 0 sec1.22.05.3-2.32.3-2.0-1.61.20.9-1.1-0.80.6-0.2-0.3
Patch foraging water rate 12 sec0.50.82.2-1.51.5-1.4-0.30.1-0.0-0.40.1-0.20.9-1.0
Patch foraging water rate 18 sec1.21.63.6-1.71.6-1.9-1.41.21.1-0.9-1.11.1-0.20.6
Patch foraging water rate 24 sec0.40.51.3-0.70.7-0.20.3-0.7-0.50.10.7-1.01.1-0.9
Patch foraging water rate 6 sec0.30.41.3-1.11.1-0.8-0.50.1-0.0-0.60.1-0.20.7-0.7
Seeking ratio, delayed vs. immediate footshock1.61.83.41.3-1.41.61.6-1.1-1.8-0.41.6-0.81.2-1.0
Distance traveled before self-admin1.01.02.41.5-1.61.31.3-0.6-0.41.50.5-0.00.2-0.1
Distance traveled after self-admin0.80.92.60.5-0.5-0.30.3-0.9-0.61.61.1-1.31.2-0.8
Extensor digitorum longus weight0.10.61.90.5-0.50.50.30.50.5-0.5-1.01.4-0.81.0
Bone: elastic displacement2.62.94.01.9-2.01.72.0-2.0-1.80.71.7-1.61.6-1.3
Bone: elastic work4.05.18.12.2-2.22.22.8-2.6-2.70.22.3-1.92.3-2.2
Bone: endosteal estimation2.04.36.2-2.12.1-1.9-2.52.51.9-2.0-2.12.2-2.01.5
Bone: endosteal perimeter2.24.56.7-2.32.3-2.0-2.62.42.0-2.1-2.12.2-1.81.2
Epididymis fat weight0.40.92.41.0-1.00.80.30.60.50.3-1.01.4-1.21.6
Delta time in closed arm before/after self-admin1.71.74.11.0-1.00.6-0.01.01.21.0-1.41.7-1.92.0
Delta time in open arm before/after self-admin2.42.35.3-2.32.3-1.8-1.81.30.8-2.2-0.80.7-0.6-0.1
Diff in mean of infusions in LGA sessions0.50.52.01.4-1.40.80.20.00.00.60.10.1-0.60.8
Delay discount exponential model param0.10.10.6-0.40.4-0.8-0.30.00.00.30.1-0.20.4-0.2
Extinction: sum of active levers before priming0.10.10.20.3-0.30.50.2-0.5-0.10.00.0-0.10.00.3
Active lever presses in extinction session 61.21.23.1-1.11.1-0.8-0.0-0.8-0.7-0.21.2-1.21.7-1.7
Bone: final force0.50.81.7-0.10.20.1-1.00.71.21.3-0.80.1-1.31.2
Bone: final moment0.50.81.6-0.40.4-0.1-1.10.81.31.0-0.90.2-1.31.1
Food consumed during 24 hour testing period1.61.95.4-2.22.2-1.7-1.00.40.0-2.30.10.10.8-1.2
Glucose0.30.41.00.0-0.10.10.3-0.5-0.8-1.00.9-0.51.0-0.7
Heart weight0.50.71.9-1.41.4-1.1-0.70.40.4-1.0-0.4-0.00.1-0.5
Delay discount hyperbolic model param0.10.10.3-0.10.1-0.50.0-0.2-0.20.60.3-0.50.6-0.4
Intermittent access intake day 1-15 change0.30.31.2-0.60.5-0.50.2-0.4-0.2-0.80.10.00.9-1.1
Intermittent access intake escalation0.40.41.4-0.60.6-0.50.3-0.5-0.3-0.90.2-0.11.0-1.2
Intermittent access intake escalation 20.10.10.8-0.10.10.20.30.10.1-0.5-0.40.9-0.1-0.0
Intermitt. access day 1 inactive lever presses0.40.41.40.5-0.51.20.20.10.50.3-0.50.5-0.90.8
Intermitt. access day 15 inactive lever presses0.20.20.4-0.40.5-0.6-0.4-0.20.20.40.4-0.50.4-0.6
Intermitt. access escalation Index0.20.20.5-0.50.5-0.4-0.40.70.4-0.2-0.30.7-0.40.3
Intermittent access day 1 total infusions1.11.32.7-1.61.6-1.4-1.61.10.9-1.0-0.50.6-0.70.2
Intermittent access day 15 total infusions0.70.82.4-1.51.5-1.1-1.10.40.6-0.8-0.30.2-0.0-0.5
Intermittent access terminal intake (last 3 days)0.80.92.2-1.51.5-1.2-1.30.80.9-0.8-0.50.6-0.3-0.1
Intermittent access total infusions0.80.92.1-1.41.5-1.1-1.30.70.8-1.0-0.50.5-0.50.0
Intermittent access day 1 locomotion0.10.10.3-0.50.5-0.1-0.4-0.10.0-0.50.4-0.40.1-0.5
Intermittent access day 15 total locomotion0.70.72.3-1.11.0-0.6-0.2-0.3-0.3-1.50.5-0.40.8-1.4
Intermittent access total locomotion0.30.41.1-1.01.0-0.8-0.80.10.4-0.6-0.1-0.20.1-0.5
Intermittent access standard deviation0.00.00.10.1-0.10.30.3-0.20.1-0.2-0.10.30.2-0.2
Left kidney weight1.23.57.7-1.41.4-1.6-1.62.22.0-1.0-2.42.8-1.71.7
Right kidney weight0.92.44.6-1.01.0-1.1-1.41.91.8-0.4-1.92.2-1.71.8
Cocaine induced anxiety1.41.64.81.9-1.82.21.2-0.9-0.51.60.6-0.7-0.20.2
Post-drug Anxiety0.40.51.30.6-0.60.4-0.40.50.70.8-0.50.4-1.11.1
Baseline Anxiety2.02.13.9-1.81.8-2.0-1.81.61.0-1.7-1.11.1-0.90.6
Tail length6.319.028.9-3.33.3-4.2-5.25.44.5-2.5-4.84.7-4.64.5
Length with tail4.014.522.0-2.32.4-3.0-4.54.64.7-0.6-4.54.0-4.44.6
Length without tail0.20.42.40.5-0.40.5-0.3-0.00.81.6-0.2-0.3-0.30.7
Times rat made contact with spout0.30.40.80.3-0.30.4-0.40.60.5-0.6-0.70.9-0.80.9
Lifetime Intake1.01.12.7-1.61.6-1.4-1.40.70.8-1.0-0.50.4-0.3-0.1
Liver weight, left1.32.06.10.5-0.50.8-0.71.41.30.6-1.51.6-2.42.5
Liver weight, right2.64.412.70.6-0.60.3-1.42.22.21.0-2.52.2-3.23.6
Locomotor activity0.20.30.8-0.70.7-0.7-0.50.40.90.9-0.40.3-0.00.0
Locomotor testing distance1.22.03.2-1.81.8-1.7-1.71.41.8-0.2-1.41.4-0.60.6
Locomotor testing rearing1.62.54.5-1.11.1-1.3-1.91.82.10.0-1.91.8-1.51.7
Locomotion in novel chamber1.11.32.60.2-0.20.91.4-1.5-1.40.21.3-1.21.4-1.6
Locomotion in novel chamber post-restriction1.11.35.0-1.51.4-0.8-0.3-0.2-0.8-2.20.5-0.21.1-1.5
Fecal boli incidents, locomotor time 10.80.92.0-0.40.41.30.9-1.0-1.2-1.40.8-0.60.4-1.2
Change in fecal boli incidents, locomotor task0.30.31.00.7-0.7-0.3-0.20.30.01.00.1-0.2-0.20.8
Time >=10cm from walls, locomotor time 10.40.41.6-1.21.3-0.7-0.60.40.2-0.2-0.0-0.2-0.0-0.3
Bouts of movement, locomotor time 10.10.10.3-0.50.6-0.3-0.60.50.4-0.2-0.10.1-0.4-0.2
Total resting periods, locomotor time 10.10.10.5-0.20.20.2-0.0-0.1-0.2-0.10.5-0.50.2-0.7
Rest time, locomotor task time 10.10.20.7-0.10.1-0.4-0.2-0.1-0.30.40.6-0.80.2-0.2
Distance moved, locomotor task time 10.40.51.8-0.10.1-0.0-0.20.70.6-0.6-1.11.3-0.70.8
Vertical activity count, locomotor time 10.60.61.3-0.50.5-0.1-0.60.70.9-0.2-1.11.1-1.01.0
Time >=10cm from walls, locomotor time 22.32.55.3-1.81.8-2.0-2.31.71.70.4-1.10.5-1.41.3
Bouts of movement, locomotor time 21.92.14.9-0.70.7-0.6-1.41.71.90.5-1.71.4-2.21.7
Total resting periods, locomotor time 21.21.33.8-0.20.3-0.1-1.01.31.50.6-1.41.2-1.91.4
Rest time, locomotor task time 21.92.24.42.1-2.11.71.7-1.4-1.11.81.1-1.10.6-0.5
Distance moved, locomotor task time 22.63.04.9-2.22.2-2.0-2.11.91.6-1.3-1.61.6-1.01.0
Vertical activity count, locomotor time 21.71.82.6-1.31.3-0.9-1.61.41.6-0.3-1.61.2-1.61.5
Light reinforcement 11.83.37.62.7-2.82.42.3-1.7-1.51.61.1-0.71.0-0.6
Light reinforcement 21.82.44.71.1-1.21.02.0-1.9-1.8-0.31.5-0.92.2-2.0
Bone: marrow area1.83.95.7-1.91.9-1.7-2.32.41.8-1.9-2.02.2-1.91.5
Bone: maximum diameter2.13.96.9-2.32.3-2.2-2.62.22.1-1.3-1.91.7-1.51.2
Bone: maximum force0.30.51.2-0.40.5-0.2-1.10.80.90.3-0.60.2-1.00.8
Bone: maximum moment0.30.51.1-0.60.7-0.3-1.10.80.9-0.0-0.70.4-0.90.6
Mean time between licks in bursts7.310.315.4-3.23.2-3.1-3.63.73.9-0.7-3.73.1-3.32.6
Mean num. licks in bursts1.82.16.0-2.52.5-2.1-1.61.00.7-1.5-0.40.30.0-0.2
Cd content in liver0.30.30.80.7-0.70.80.40.1-0.3-0.9-0.20.7-0.40.0
Co content in liver2.93.45.7-1.91.9-1.9-2.42.22.0-1.0-1.81.4-1.91.4
Cu content in liver1.72.13.1-1.41.4-1.3-1.81.71.4-1.3-1.51.4-1.51.2
Fe content in liver0.10.10.3-0.10.10.0-0.40.40.3-0.4-0.30.2-0.60.4
K content in liver0.40.30.90.5-0.51.00.3-0.10.70.8-0.70.3-0.60.5
Mg content in liver0.00.10.2-0.30.30.1-0.0-0.00.3-0.2-0.40.1-0.10.0
Mn content in liver2.42.73.91.6-1.71.82.0-1.9-1.71.11.7-1.71.5-1.1
Na content in liver0.30.31.9-0.70.7-0.4-0.3-0.0-0.3-1.40.2-0.20.4-0.6
Rb content in liver0.81.03.5-1.31.3-0.9-1.10.80.5-1.9-0.60.6-0.50.2
Se content in liver2.32.85.82.3-2.32.41.8-1.7-1.50.91.4-1.50.7-0.6
Sr content in liver1.00.92.20.3-0.3-0.01.2-1.0-1.2-0.11.0-0.71.5-1.4
Zn content in liver1.61.84.9-2.22.2-1.7-0.80.80.5-2.0-0.70.80.1-0.6
Bone: minimum diameter2.24.27.0-1.21.2-1.2-2.32.42.6-0.4-2.62.3-2.52.3
Time in familiar zone, hab. session 10.20.10.3-0.20.2-0.5-0.30.40.50.0-0.50.4-0.30.5
Time in novel zone, hab. session 10.10.10.20.5-0.50.4-0.00.0-0.20.20.2-0.1-0.20.3
Total zone transitions, hab. session 10.40.61.7-0.00.0-0.30.1-0.7-0.9-0.51.0-1.11.3-1.2
Total locomotion distance, hab. session 11.21.74.40.6-0.60.1-0.71.21.51.4-1.61.3-1.72.1
Locomotion velocity, hab. session 10.91.32.90.5-0.40.2-0.60.91.51.6-1.41.1-1.51.7
Time in familiar zone, hab. session 21.92.03.8-1.71.7-1.9-1.81.61.2-0.3-1.10.9-1.11.1
Time in novel zone, hab. session 21.41.42.31.1-1.21.41.5-1.5-1.00.21.0-0.71.3-1.3
Total zone transitions, hab. session 20.70.92.9-1.41.4-1.7-1.00.10.1-0.60.3-0.41.0-0.9
Total locomotion distance, hab. session 22.43.26.7-0.40.4-1.0-1.71.72.62.0-2.21.6-2.02.4
Locomotion velocity, hab. session 22.63.47.3-0.30.3-0.9-1.71.82.72.0-2.31.7-2.12.5
Novel to familiar place preference ratio0.91.02.3-0.50.6-0.4-1.30.81.51.5-0.8-0.0-1.20.9
Novelty place preference1.01.02.5-0.50.6-0.5-1.30.81.61.6-0.8-0.1-1.20.9
Time in novel zone, NPP test1.21.22.8-0.70.8-0.7-1.50.91.71.6-0.9-0.0-1.21.0
Total zone transitions, NPP test0.40.61.9-0.20.10.10.5-0.9-0.8-0.70.8-0.51.4-1.4
Total locomotion distance, NPP test0.81.12.90.7-0.70.60.10.41.31.7-1.31.3-1.01.3
Locomotion velocity, NPP test0.81.13.01.1-1.10.90.50.21.01.7-1.11.2-0.81.1
Intraocular pressure1.62.36.9-0.10.00.20.9-0.9-2.4-2.61.8-1.11.7-1.9
Delta distance traveled before/after self-admin1.61.75.1-1.81.9-2.3-2.10.90.8-0.2-0.4-0.4-0.10.2
Delta ambulatory time before/after self-admin1.11.24.0-1.71.7-2.0-1.70.40.3-0.20.0-0.80.4-0.3
Parametrial fat weight0.50.92.11.4-1.41.31.2-0.4-0.7-1.0-0.21.00.1-0.1
Pavlov. Cond. lever latency0.81.02.11.5-1.51.01.1-0.9-0.81.40.7-0.90.6-0.0
Pavlov. Cond. magazine entry latency2.02.65.1-2.32.3-2.2-1.71.51.4-1.3-1.31.4-0.70.5
Pavlov. Cond. change in total contacts1.51.62.9-1.71.7-1.3-1.51.30.9-1.6-0.90.9-0.90.4
Pavlov. Cond. index score2.02.65.0-2.22.2-1.9-1.71.51.2-2.1-1.21.5-0.70.2
Pavlov. Cond. latency score2.02.54.9-2.22.2-1.8-1.71.51.2-2.0-1.21.4-0.80.2
Pavlov. Cond. lever contacts1.01.23.4-1.41.4-1.0-1.01.00.7-1.9-0.91.2-0.60.1
Pavlov. Cond. magazine entry number2.12.65.72.4-2.42.01.6-1.3-1.02.21.0-1.20.40.0
Pavlov. Cond. intertrial magazine entries0.40.51.11.1-1.01.00.4-0.6-0.40.80.5-0.60.10.1
Pavlov. Cond. lever-magazine prob. diff.1.72.14.5-2.02.0-1.7-1.41.30.9-2.1-1.01.3-0.60.0
Pavlov. Cond. response bias0.91.12.0-1.41.4-1.2-1.01.00.8-1.4-0.91.1-0.60.3
Pavlov. Cond. lever latency10.013.530.25.5-5.55.34.0-3.3-2.93.22.6-2.51.0-0.3
Pavlov. Cond. magazine entry latency1.21.44.1-2.02.0-1.9-0.50.30.4-1.0-0.30.20.8-1.0
Pavlov. Cond. change in total contacts7.510.424.5-4.94.9-5.0-3.62.72.4-2.9-2.01.7-0.4-0.1
Pavlov. Cond. index score6.88.721.2-4.64.6-4.3-3.02.42.3-2.6-2.01.8-0.5-0.1
Pavlov. Cond. latency score5.77.117.9-4.24.2-4.0-2.72.11.9-2.5-1.71.6-0.2-0.3
Pavlov. Cond. lever contacts10.514.432.3-5.75.7-5.4-4.23.43.0-3.5-2.72.5-1.10.4
Pavlov. Cond. magazine entry number2.63.29.23.0-3.02.91.4-0.8-0.81.80.6-0.4-0.71.1
Pavlov. Cond. intertrial magazine entries1.31.73.0-0.50.5-0.6-1.41.61.4-0.9-1.51.7-1.71.6
Pavlov. Cond. lever-magazine prob. diff.6.68.419.9-4.54.4-4.3-3.02.52.3-2.5-2.11.8-0.60.0
Pavlov. Cond. response bias9.813.331.4-5.65.6-5.3-3.93.12.8-3.4-2.42.3-0.7-0.0
Time in closed arm before self-admin1.11.32.6-1.31.3-1.5-0.4-0.5-0.30.60.9-1.51.6-1.4
Time in closed arm after self-admin0.90.93.31.0-0.90.61.0-0.9-0.61.80.9-1.00.5-0.5
Time in open arm before self-admin2.72.97.72.8-2.82.62.3-1.3-1.21.10.8-0.20.10.3
Time in open arm after self-admin0.60.61.7-0.40.4-0.2-0.50.90.5-1.3-0.91.0-1.00.7
Bone: periosteal estimation1.63.45.0-1.81.9-1.5-2.22.21.9-1.5-2.02.0-1.81.3
Bone: periosteal perimeter1.62.64.2-1.81.8-1.6-2.11.81.8-1.0-1.71.6-1.31.0
Bone: post-yield work0.20.30.6-0.60.6-0.8-0.80.60.40.2-0.30.3-0.30.4
Progressive ratio test 1 active lever presses0.00.00.1-0.0-0.0-0.2-0.2-0.1-0.0-0.20.2-0.30.1-0.3
Progressive ratio test 1 breakpoint0.00.00.1-0.10.1-0.2-0.30.10.1-0.4-0.0-0.1-0.1-0.1
Progressive ratio test 1 inactive lever presses0.20.20.6-0.80.8-0.2-0.60.20.4-0.8-0.30.1-0.3-0.1
Progressive ratio test 2 active lever presses0.80.81.7-1.21.2-0.8-1.30.70.9-1.3-0.70.4-0.70.2
Progressive ratio test 2 breakpoint0.91.02.0-1.31.3-0.9-1.40.81.0-1.2-0.80.5-0.80.3
Progressive ratio test 2 inactive lever presses0.30.31.1-1.01.1-0.5-0.7-0.10.3-0.30.1-0.50.1-0.4
Incentive Sensitization - Responses1.81.83.0-1.71.7-1.2-1.71.31.4-1.2-1.31.0-1.20.6
Incentive Sensitization - Breakpoint1.31.32.4-1.51.6-1.1-1.51.01.2-1.1-1.00.9-0.90.4
Sum of active levers in priming session hrs 5-60.30.32.10.4-0.3-0.2-0.2-0.30.21.40.4-0.60.50.1
Progressive ratio0.40.51.20.1-0.10.10.7-0.5-0.9-0.70.7-0.41.0-1.1
Food seeking constrained by brief footshock1.62.03.0-1.31.3-1.7-1.71.61.6-0.6-1.61.5-1.21.2
Seeking ratio, punishment vs. effort2.02.53.9-1.11.1-1.2-1.81.72.0-0.1-2.01.7-1.81.9
Retroperitoneal fat weight2.06.716.52.3-2.31.6-0.21.82.51.4-3.13.5-3.24.1
Reaction time number correct0.60.82.40.1-0.10.10.6-1.1-0.51.30.9-1.51.1-1.0
Reaction time mean minus median0.60.81.7-1.01.0-0.7-1.00.91.3-0.1-1.10.9-0.90.6
Reaction time mean minus median AUC0.40.61.3-1.11.2-0.8-0.90.61.00.1-0.60.3-0.50.3
Reaction time num false alarms1.11.53.71.8-1.71.90.7-0.20.41.8-0.40.3-1.01.0
Reaction time num false alarms AUC0.81.13.81.5-1.42.00.9-0.50.11.5-0.10.0-0.70.5
Reaction time trials correct on left0.60.82.40.1-0.10.10.6-1.1-0.51.30.9-1.51.1-1.0
Reaction time trials on left0.60.92.40.1-0.10.10.7-1.1-0.61.30.9-1.61.1-1.0
Reaction time mean0.81.12.61.0-0.91.10.10.31.01.6-0.70.3-1.41.6
Reaction time mean AUC0.70.92.31.1-1.11.30.20.00.61.5-0.4-0.0-1.11.4
Median of all reaction times1.01.33.91.5-1.41.60.5-0.20.52.0-0.3-0.1-1.11.5
Reaction time omissions0.30.41.00.9-0.91.00.7-0.30.31.0-0.30.1-0.30.4
Reaction time false alarm rate0.81.13.51.5-1.41.90.7-0.00.41.0-0.50.8-1.10.9
Reaction time premature initiation rate2.83.87.4-1.61.6-1.8-1.72.42.0-1.5-2.32.7-1.91.6
Reaction time premature initiations1.11.52.3-1.41.4-1.4-0.91.31.4-0.8-1.41.5-0.90.6
Std. dev. reaction times1.21.73.8-0.50.5-0.2-1.11.41.80.0-1.71.4-2.01.8
Reaction time trials completed0.60.92.40.1-0.10.10.7-1.1-0.61.30.9-1.61.1-1.0
Reaction time trials AUC0.40.62.00.1-0.10.00.5-0.9-0.31.40.7-1.30.8-0.7
Run reversals in cocaine runway, females2.42.35.70.0-0.1-0.4-0.91.71.8-0.5-2.22.4-1.82.1
Run reversals in cocaine runway, males0.30.30.60.3-0.30.60.4-0.4-0.7-0.70.7-0.60.4-0.4
Latency to leave start box in cocaine runway0.60.62.11.4-1.40.91.0-0.4-0.5-0.30.10.3-0.30.1
Latency to leave start box in cocaine runway, F0.50.51.11.0-1.10.50.40.30.3-0.3-0.60.9-1.00.9
Latency to leave start box in cocaine runway, M1.21.11.90.8-0.81.01.3-1.3-1.4-0.51.2-0.80.9-1.3
Std. dev. time between licks in bursts3.74.46.9-1.41.4-1.3-2.22.52.6-0.2-2.62.5-2.62.1
Total sessions with >9 infusions1.41.53.9-2.01.9-1.9-0.90.20.0-1.60.1-0.30.8-1.2
Short access day 1 total inactive lever presses0.10.10.2-0.10.10.5-0.3-0.30.3-0.10.1-0.4-0.4-0.1
Short access day 10 total inactive lever presses0.30.31.50.6-0.61.20.7-0.7-0.30.40.4-0.30.1-0.2
Short access day 1 total infusions1.61.74.1-2.02.0-1.7-1.61.01.0-1.2-0.90.6-0.60.2
Short access day 10 total infusions1.51.62.9-1.71.7-1.6-1.71.21.0-1.5-0.90.9-0.70.2
Short access total infusions1.01.12.4-1.61.6-1.5-1.30.90.8-1.1-0.70.6-0.40.1
Short access day 1 locomotion1.31.43.4-1.11.1-0.40.3-0.8-1.2-1.81.1-1.01.4-1.9
Short access day 10 total locomotion0.10.10.4-0.30.3-0.0-0.10.00.6-0.1-0.40.3-0.1-0.1
Short access total locomotion0.20.20.5-0.30.3-0.1-0.0-0.3-0.1-0.70.3-0.40.4-0.7
One hour access (0.3 mA shock)0.80.92.4-1.51.5-1.1-1.00.70.8-0.8-0.70.9-0.3-0.0
Compulsive drug intake1.11.12.50.6-0.60.91.2-1.1-1.6-0.31.3-1.11.1-1.1
One hour access (shock baseline)1.51.72.8-1.61.7-1.4-1.61.21.6-0.4-1.31.2-0.90.7
Social response proportion0.50.61.60.6-0.60.80.50.10.91.3-0.90.8-0.80.6
Social responses1.51.94.40.3-0.30.5-0.61.02.11.7-1.91.4-1.91.5
Social time1.92.55.62.0-2.01.71.5-1.7-0.72.41.0-1.60.7-0.8
Soleus weight0.92.68.00.2-0.20.4-0.51.71.80.1-2.32.8-2.31.9
Bone: stiffness1.11.74.20.00.00.2-1.41.31.71.2-1.40.8-2.11.9
Tibialis anterior weight0.41.22.6-0.50.5-0.6-1.01.21.50.4-1.41.1-1.41.6
Time to tail flick, vehicle, before self-admin0.10.10.5-0.10.1-0.7-0.60.20.40.60.0-0.30.3-0.0
Time to tail flick, vehicle, after self-admin1.51.64.2-1.91.9-1.6-1.00.4-0.2-2.00.3-0.40.6-1.2
Time to tail flick, test, before self-admin1.61.52.9-1.11.1-1.7-1.61.60.9-1.5-0.81.3-0.70.6
Time to tail flick, test, after self-admin2.82.94.6-1.21.2-1.5-2.02.11.9-0.6-1.92.0-1.81.8
Delta time to tail flick, vehicle, before/after SA1.11.15.8-1.31.3-0.50.0-0.1-0.9-2.40.4-0.20.6-1.2
Delta time to tail flick, test, before/after SA0.20.20.70.5-0.50.60.3-0.10.10.8-0.30.1-0.30.4
Tibia length0.51.34.7-2.12.2-1.3-1.20.20.4-0.80.2-0.80.4-0.7
Ambulatory time before self-admin1.11.22.41.5-1.51.41.4-0.8-0.71.30.9-0.40.5-0.4
Ambulatory time after self-admin0.91.03.00.1-0.1-0.7-0.0-0.9-0.61.61.2-1.71.3-0.9
Bone: tissue strength2.42.34.10.8-0.80.81.5-1.8-1.80.21.9-1.82.0-2.0
Total heroin consumption0.30.41.5-0.50.6-0.8-0.60.20.71.2-0.2-0.10.30.2
Bone: trabecular number1.21.92.71.3-1.31.31.4-1.6-1.7-0.11.6-1.31.4-1.4
Bone: trabecular spacing0.20.30.7-0.80.8-0.40.0-0.0-0.0-0.7-0.00.30.6-0.7
Bone: trabecular thickness0.60.81.70.1-0.0-0.2-1.10.81.11.1-0.70.1-1.31.3
Bone: trabecular tissue density2.53.68.90.6-0.60.5-1.51.72.41.8-2.11.4-2.93.0
Water consumed over 24 hours0.40.50.90.9-0.90.90.5-0.7-0.80.00.8-0.80.6-0.2
Number of responses in last shaping day0.50.51.2-0.60.7-0.1-0.90.90.8-0.6-0.80.6-1.10.5