Hub : Genes

Fchsd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA alternative TSS XM_063262817.1 0.08 0.05 3.0e-03 0.01 0.03 0.01 0.02 6.5e-02 1.7e-02 9.1e-02 3.8e-02
2 BLA alternative TSS NM_001395742.1 0.09 0.06 3.4e-03 0.02 0.02 0.01 0.02 3.9e-02 3.5e-02 7.2e-02 2.3e-02
3 NAcc mRNA stability Fchsd2 0.02 0.02 3.7e-03 0.01 0.01 0 0 1.5e-02 1.0e-02 5.7e-02 5.2e-02
4 PL gene expression Fchsd2 0.06 0.04 1.3e-04 0.01 0.01 0.02 0.01 4.2e-02 1.2e-02 2.0e-03 7.6e-03
5 Brain mRNA stability Fchsd2 0.12 0.06 5.2e-09 0.09 0.09 0.09 0.09 1.8e-08 1.0e-08 1.9e-08 1.1e-08
6 pVTA gene expression Fchsd2 0.17 0.09 1.2e-08 0.12 0.11 0.11 0.11 9.6e-10 2.7e-09 2.0e-09 2.8e-09
7 IC gene expression Fchsd2 0.16 0.09 4.7e-04 0.09 0.07 0.07 0.07 1.7e-04 6.1e-04 5.8e-04 6.3e-04
8 Adipose gene expression Fchsd2 0.04 0.03 1.5e-03 0.02 0.01 0.02 0.01 2.1e-03 9.2e-03 5.6e-03 6.7e-03
9 Liver alternative TSS NM_001395742.1 0.05 0.04 1.8e-03 0.03 0.01 0.02 0.02 7.0e-04 6.9e-03 2.6e-03 2.3e-03
10 Brain gene expression Fchsd2 0.09 0.05 3.3e-07 0.06 0.06 0.06 0.06 4.2e-06 2.6e-06 4.1e-06 4.4e-06
11 NAcc gene expression Fchsd2 0.07 0.04 9.2e-09 0.04 0.06 0.05 0.05 2.4e-07 4.8e-09 1.2e-07 2.4e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.50.81.4-0.70.70.90.80.91.01.1-1.20.41.00.9
Area under the delay curve0.00.10.2-0.2-0.10.10.2-0.1-0.20.2-0.2-0.4-0.3-0.4
BMI with tail0.41.23.40.20.3-1.00.7-1.3-1.0-1.00.61.2-1.8-1.7
BMI without tail0.92.85.81.3-0.8-2.1-0.8-2.4-1.7-1.81.70.1-2.3-1.9
Body weight1.46.010.31.2-1.3-2.3-2.0-2.9-2.9-2.92.7-1.5-3.2-3.1
Weight adjusted by age0.40.61.20.5-0.6-0.7-0.6-0.9-0.6-1.10.7-0.7-0.8-0.7
Bone surface0.40.71.81.1-1.4-0.9-1.2-0.7-0.4-0.20.3-1.4-0.2-0.1
Bone volume0.20.41.20.7-1.0-0.6-0.9-0.5-0.5-0.30.3-1.1-0.2-0.2
Breakpoint value in progressive ratio session0.91.11.9-1.31.31.40.91.40.70.8-0.51.10.90.8
Number of licking bursts1.11.76.1-2.52.21.71.50.70.50.5-0.90.8-0.3-0.6
Context. condit. distance diff. score0.60.72.91.7-1.1-1.1-1.1-0.3-0.3-0.20.7-0.20.50.7
Locomotion velocity, session 12.12.33.8-0.91.41.21.71.41.61.6-1.82.01.41.4
Locomotion distance, session 10.40.51.40.8-0.1-0.30.20.30.50.5-0.71.20.81.1
Locomotion velocity, session 20.10.11.20.30.2-0.30.3-0.30.1-0.1-0.11.1-0.00.2
Locomotion distance, session 20.20.21.70.6-0.0-0.50.2-0.0-0.2-0.10.01.30.20.4
Locomotion velocity, session 30.20.20.80.7-0.3-0.2-0.30.30.20.30.00.10.80.9
Locomotion distance, session 30.50.62.00.7-0.3-0.1-0.00.50.90.9-0.60.41.31.4
Stereotopy head waving bouts, day 30.50.61.2-0.3-0.1-0.2-0.6-0.6-1.1-0.80.9-0.8-1.0-1.1
Stereotopy head waving duration, day 30.00.00.10.3-0.2-0.2-0.20.0-0.20.1-0.10.10.20.2
Locomotion velocity, session 70.70.71.7-0.71.10.71.00.80.80.8-0.51.30.70.7
Locomotion distance, session 70.10.10.3-0.50.50.30.50.2-0.0-0.10.20.2-0.2-0.3
Stereotopy head waving bouts, day 71.01.23.51.9-1.8-1.2-1.5-0.50.00.30.2-0.80.71.0
Stereotopy head waving duration, day 71.11.34.32.1-1.9-1.5-1.5-0.8-0.1-0.10.3-0.60.40.7
Locomotion velocity, session 80.40.51.31.1-0.8-0.9-1.1-0.5-0.5-0.30.8-0.50.10.2
Locomotion distance, session 80.71.03.81.9-1.1-1.5-1.1-0.6-0.8-0.70.90.40.10.4
Degree of sensitization distance2.22.35.2-0.2-0.3-0.7-0.8-1.3-2.0-2.01.8-1.0-2.2-2.3
Degree of sensitization stereotypy1.92.16.82.6-2.4-1.7-1.9-0.8-0.2-0.10.5-1.10.71.0
Conditioned locomotion0.20.20.7-0.3-0.00.3-0.30.6-0.8-0.70.6-0.6-0.0-0.2
Cocaine response after cond. corrected0.40.51.8-1.31.00.80.90.10.10.3-0.30.5-0.5-0.7
Cocaine response after cond. not corrected0.50.51.1-0.80.80.61.10.30.81.0-0.80.90.10.1
Cocaine response before conditioning0.91.02.71.2-0.6-0.40.20.41.31.4-0.90.71.41.6
Saline control response2.43.15.92.0-2.1-1.9-2.4-1.6-1.6-1.31.7-2.2-1.0-0.9
Bone: connectivity density1.32.14.1-0.50.80.91.41.02.01.8-2.01.31.61.6
Bone: cortical apparent density0.50.62.5-1.61.31.00.60.3-0.3-0.30.30.0-0.6-0.9
Bone: cortical area0.50.81.50.6-0.8-0.9-1.0-0.9-1.2-0.91.0-0.8-1.0-0.9
Bone: cortical porosity0.20.20.70.5-0.30.1-0.10.60.40.3-0.4-0.30.80.8
Bone: cortical porosity0.30.30.80.6-0.5-0.0-0.20.50.50.4-0.5-0.40.90.8
Bone: cortical thickness0.30.51.1-0.91.00.80.80.70.30.5-0.41.00.30.3
Bone: cortical thickness0.10.10.30.3-0.4-0.3-0.4-0.0-0.6-0.50.4-0.2-0.1-0.1
Bone: cortical tissue density0.50.62.6-1.61.31.10.70.4-0.2-0.20.20.1-0.5-0.7
Condit. Reinf. active minus inactive responses1.31.42.80.7-1.1-1.0-1.4-1.1-1.3-0.91.7-1.4-1.1-1.1
Condit. Reinf. active-inactive response ratio2.02.14.11.1-1.6-1.2-1.7-1.4-1.3-1.21.7-2.0-1.2-1.2
Condit. Reinf. active responses0.60.81.70.3-0.6-0.5-1.0-0.6-1.2-0.81.3-1.0-0.9-0.9
Condit. Reinf. inactive responses0.10.10.3-0.30.50.30.40.4-0.2-0.0-0.20.60.00.0
Incentive salience index mean0.91.11.80.7-1.0-0.9-1.2-1.0-1.2-1.01.4-1.1-1.0-1.0
Condit. Reinf. lever presses0.10.10.30.5-0.4-0.5-0.3-0.4-0.2-0.20.10.2-0.2-0.1
Condit. Reinf. active minus inactive responses6.58.414.43.7-3.8-3.5-3.5-2.9-2.5-2.72.6-2.5-1.7-1.4
Condit. Reinf. active-inactive response ratio0.80.92.31.5-1.5-1.3-1.2-1.0-0.4-0.50.6-0.7-0.3-0.1
Condit. Reinf. active responses9.813.720.94.4-4.6-4.4-4.4-3.7-3.5-3.73.4-3.1-2.5-2.1
Condit. Reinf. inactive responses6.88.811.53.2-3.3-3.4-3.3-2.9-3.2-3.42.9-2.3-2.3-2.0
Condit. Reinf. lever presses11.415.732.75.7-5.4-5.2-4.6-3.9-3.4-3.83.2-2.5-1.9-1.4
Condit. Reinf. lever reinforcers received10.114.122.74.7-4.8-4.6-4.5-3.8-3.4-3.73.4-3.1-2.4-1.9
Conditioned reinforcement - actives0.20.31.31.1-0.7-0.5-0.10.20.30.3-0.3-0.00.70.8
Conditioned reinforcement - inactives0.10.10.2-0.40.50.40.30.5-0.2-0.10.0-0.40.1-0.1
Conditioned locomotion0.81.03.11.2-0.6-0.30.40.80.90.6-1.10.81.61.7
Patch foraging indifference point 0 sec1.01.85.92.4-2.0-1.9-1.5-1.1-0.8-0.80.7-1.0-0.3-0.0
Patch foraging indifference point AUC0.60.91.50.4-0.9-0.9-0.7-1.2-1.0-1.10.9-0.8-1.2-1.1
Delay disc. indifference point, 0s delay0.91.01.81.3-1.2-1.3-1.1-1.0-1.2-0.70.8-0.6-0.7-0.6
Delay disc. indifference point, 16s delay0.10.21.1-0.3-0.20.4-0.10.3-0.20.50.0-1.0-0.0-0.2
Delay disc. indifference point, 2s delay1.11.21.71.1-1.3-1.3-1.2-1.3-1.1-1.00.8-1.0-1.0-0.9
Delay disc. indifference point, 24s delay0.40.41.6-1.30.91.00.60.80.00.40.1-0.20.0-0.2
Delay disc. indifference point, 4s delay2.52.63.51.4-1.6-1.7-1.7-1.8-1.9-1.61.5-1.3-1.6-1.5
Delay disc. indifference point, 8s delay0.00.10.2-0.20.10.20.50.10.10.3-0.4-0.1-0.0-0.1
Indifference point function ln k0.40.82.30.7-0.20.10.01.00.91.1-0.70.41.51.5
Indifference point function log k0.40.82.30.7-0.20.10.01.00.91.1-0.70.41.51.5
Patch foraging total patch changes 0 sec0.81.65.02.2-1.8-1.8-1.3-1.1-0.8-0.70.6-0.9-0.3-0.1
Patch foraging total patch changes 12 sec2.02.63.51.4-1.6-1.7-1.5-1.8-1.8-1.91.6-1.1-1.7-1.5
Patch foraging total patch changes 18 sec1.11.73.71.9-1.9-1.8-1.2-1.4-0.9-1.20.8-1.0-0.9-0.7
Patch foraging total patch changes 24 sec1.42.53.01.4-1.6-1.7-1.5-1.7-1.5-1.71.3-1.5-1.6-1.5
Patch foraging total patch changes 6 sec0.20.30.90.9-0.8-0.8-0.4-0.5-0.5-0.30.3-0.3-0.3-0.2
Patch foraging time to switch 0 sec1.53.06.9-2.62.42.41.91.81.31.2-1.31.20.90.6
Patch foraging water rate 0 sec0.81.85.32.3-2.0-1.9-1.5-1.1-0.9-0.60.9-0.9-0.3-0.1
Patch foraging water rate 12 sec0.30.62.61.6-0.8-1.1-0.1-0.2-0.00.10.11.00.40.7
Patch foraging water rate 18 sec0.91.42.91.7-1.4-1.6-1.4-1.3-1.0-0.81.1-0.4-0.6-0.4
Patch foraging water rate 24 sec0.30.41.20.8-0.1-0.20.30.60.50.8-0.40.71.01.1
Patch foraging water rate 6 sec0.20.31.31.1-0.5-0.7-0.3-0.10.1-0.0-0.10.60.40.6
Seeking ratio, delayed vs. immediate footshock1.82.23.7-1.51.61.71.51.51.91.3-1.80.71.31.2
Distance traveled before self-admin0.30.41.3-1.11.10.80.70.4-0.0-0.2-0.20.9-0.1-0.2
Distance traveled after self-admin1.61.93.1-1.01.41.41.11.71.20.9-1.21.81.61.6
Extensor digitorum longus weight0.10.62.0-0.20.0-0.40.1-1.1-0.6-0.50.40.0-1.4-1.4
Bone: elastic displacement3.23.75.3-2.02.22.12.11.81.92.3-1.81.91.51.5
Bone: elastic work4.86.39.1-2.22.52.42.92.22.73.0-2.72.62.01.9
Bone: endosteal estimation2.14.66.42.1-2.5-2.3-2.4-2.4-1.9-1.71.8-2.5-1.9-1.8
Bone: endosteal perimeter2.24.86.92.3-2.6-2.5-2.5-2.5-2.0-1.91.8-2.1-1.8-1.6
Epididymis fat weight0.10.41.3-1.11.10.70.90.30.20.2-0.10.5-0.3-0.5
Delta time in closed arm before/after self-admin0.70.62.4-1.00.50.20.4-0.6-0.5-0.50.5-0.3-1.4-1.5
Delta time in open arm before/after self-admin2.12.14.22.1-2.0-1.8-1.9-1.4-1.2-1.01.0-1.4-0.6-0.4
Diff in mean of infusions in LGA sessions0.91.15.0-2.21.41.80.51.00.30.3-0.4-0.40.2-0.1
Delay discount exponential model param0.00.00.10.20.0-0.1-0.30.10.1-0.20.30.20.30.3
Extinction: sum of active levers before priming0.10.20.50.3-0.2-0.4-0.6-0.4-0.5-0.20.7-0.1-0.4-0.4
Active lever presses in extinction session 61.41.44.30.50.10.40.61.50.90.9-1.01.12.02.1
Bone: final force0.20.31.5-0.3-0.10.2-0.40.1-0.7-0.60.5-1.2-0.4-0.6
Bone: final moment0.20.31.4-0.1-0.3-0.0-0.5-0.1-0.8-0.60.6-1.2-0.4-0.6
Food consumed during 24 hour testing period0.81.14.52.1-1.7-1.4-1.1-0.50.1-0.5-0.3-0.30.71.0
Glucose0.10.10.3-0.10.30.20.20.00.60.5-0.50.40.30.4
Heart weight0.30.51.41.2-1.2-0.9-0.9-0.4-0.4-0.10.3-0.80.00.1
Delay discount hyperbolic model param0.10.10.30.00.20.2-0.00.40.30.10.10.40.50.5
Intermittent access intake day 1-15 change0.30.72.30.60.4-0.20.60.20.70.9-0.91.50.81.1
Intermittent access intake escalation0.30.71.70.70.2-0.30.40.20.81.0-1.11.30.91.2
Intermittent access intake escalation 20.20.20.50.7-0.2-0.50.1-0.20.30.3-0.50.60.20.3
Intermitt. access day 1 inactive lever presses0.10.41.4-1.21.00.80.60.3-0.10.10.10.2-0.4-0.6
Intermitt. access day 15 inactive lever presses0.40.81.5-1.00.91.20.91.20.40.7-0.70.30.90.8
Intermitt. access escalation Index0.00.00.10.2-0.3-0.2-0.3-0.20.0-0.00.2-0.3-0.1-0.1
Intermittent access day 1 total infusions0.50.92.41.5-1.6-1.1-1.2-0.4-0.5-0.40.4-1.10.20.3
Intermittent access day 15 total infusions0.30.52.01.4-1.0-0.9-0.6-0.1-0.10.4-0.2-0.20.60.8
Intermittent access terminal intake (last 3 days)0.60.72.81.7-1.4-1.2-1.0-0.4-0.5-0.30.2-0.50.20.4
Intermittent access total infusions0.80.93.11.8-1.4-1.4-1.0-0.7-0.7-0.40.4-0.7-0.10.1
Intermittent access day 1 locomotion0.20.20.60.4-0.6-0.0-0.30.40.10.2-0.2-0.80.70.7
Intermittent access day 15 total locomotion0.50.92.40.7-0.20.00.50.70.91.1-1.20.71.41.5
Intermittent access total locomotion0.20.31.01.0-0.8-0.5-0.50.0-0.00.0-0.2-0.50.60.7
Intermittent access standard deviation0.10.30.70.30.2-0.6-0.1-0.6-0.7-0.80.30.6-0.7-0.6
Left kidney weight0.52.34.10.9-1.1-1.5-1.1-1.9-1.7-1.61.5-0.8-2.0-1.9
Right kidney weight1.04.67.21.3-1.7-2.1-1.7-2.5-2.2-2.42.1-1.8-2.7-2.6
Cocaine induced anxiety0.91.33.5-1.91.61.71.31.30.80.5-0.70.20.50.2
Post-drug Anxiety0.50.62.5-1.61.01.30.30.70.0-0.00.1-0.7-0.0-0.3
Baseline Anxiety1.11.33.01.0-1.3-1.1-1.7-1.1-1.1-0.61.3-1.5-0.7-0.6
Tail length3.212.317.62.3-3.1-3.2-4.2-3.9-3.7-3.63.9-3.8-3.4-3.3
Length with tail2.711.617.72.1-2.8-2.9-4.2-3.4-3.8-3.63.9-3.9-3.2-3.1
Length without tail0.20.72.2-0.1-0.3-0.2-1.3-0.5-1.0-0.80.8-1.5-0.6-0.7
Times rat made contact with spout0.30.30.7-0.2-0.0-0.2-0.6-0.7-0.5-0.80.3-0.7-0.8-0.8
Lifetime Intake0.91.13.81.9-1.6-1.5-1.1-0.8-0.7-0.40.4-0.7-0.00.2
Liver weight, left0.61.12.60.1-0.5-0.6-0.7-1.2-0.8-1.20.8-1.2-1.5-1.6
Liver weight, right1.22.15.6-0.5-0.1-0.4-0.8-1.4-1.6-1.31.5-1.7-2.2-2.4
Locomotor activity0.20.30.60.8-0.7-0.6-0.5-0.2-0.8-0.40.70.1-0.1-0.0
Locomotor testing distance1.32.43.41.8-1.8-1.8-1.7-1.5-1.8-1.41.6-0.9-1.1-0.9
Locomotor testing rearing1.42.85.01.2-1.4-1.6-1.9-1.7-2.2-1.82.0-1.4-1.6-1.5
Locomotion in novel chamber0.91.22.5-0.00.30.51.61.11.20.9-1.41.41.11.1
Locomotion in novel chamber post-restriction0.40.62.21.5-1.0-0.8-0.3-0.10.50.6-0.70.20.91.0
Fecal boli incidents, locomotor time 10.60.92.70.2-0.10.41.31.01.10.8-1.60.91.00.9
Change in fecal boli incidents, locomotor task0.20.20.7-0.50.30.3-0.4-0.2-0.10.60.8-0.8-0.3-0.3
Time >=10cm from walls, locomotor time 10.40.41.61.3-1.2-0.7-0.6-0.0-0.0-0.30.2-0.80.30.3
Bouts of movement, locomotor time 10.20.31.20.4-0.6-0.3-0.6-0.1-0.8-0.30.1-1.1-0.1-0.2
Total resting periods, locomotor time 10.10.10.30.1-0.10.20.00.5-0.10.3-0.5-0.50.60.5
Rest time, locomotor task time 10.40.51.0-0.30.10.70.10.90.90.9-0.6-0.61.00.9
Distance moved, locomotor task time 10.40.61.20.3-0.2-0.7-0.4-1.0-0.9-1.10.60.1-1.1-1.0
Vertical activity count, locomotor time 10.40.91.50.7-0.6-1.0-0.7-1.0-1.2-1.21.0-0.3-1.1-1.0
Time >=10cm from walls, locomotor time 22.23.35.21.8-2.2-1.8-2.2-1.4-1.9-1.52.1-2.3-1.1-1.1
Bouts of movement, locomotor time 21.82.94.80.9-1.4-1.3-1.6-1.5-2.0-1.71.9-2.2-1.9-2.0
Total resting periods, locomotor time 21.01.83.30.5-1.0-0.9-1.1-1.1-1.5-1.31.5-1.8-1.6-1.7
Rest time, locomotor task time 21.51.94.1-2.01.81.81.51.31.11.3-1.20.90.60.5
Distance moved, locomotor task time 22.42.94.72.2-2.0-2.1-2.0-1.7-1.7-1.81.5-1.4-1.0-0.8
Vertical activity count, locomotor time 21.42.02.81.4-1.4-1.5-1.4-1.3-1.5-1.71.5-1.3-1.2-1.2
Light reinforcement 11.12.75.8-2.32.41.92.31.21.21.0-1.41.90.40.3
Light reinforcement 21.62.56.4-0.91.51.01.91.11.61.5-1.92.51.31.5
Bone: marrow area1.94.15.61.9-2.4-2.2-2.2-2.3-1.8-1.71.7-2.4-1.9-1.8
Bone: maximum diameter2.03.85.42.1-2.3-2.2-2.3-2.0-1.9-1.71.8-1.9-1.5-1.3
Bone: maximum force0.10.10.8-0.1-0.20.1-0.30.1-0.3-0.20.1-0.9-0.1-0.3
Bone: maximum moment0.10.10.60.1-0.3-0.1-0.4-0.1-0.4-0.20.2-0.8-0.2-0.3
Mean time between licks in bursts4.811.714.83.0-3.6-3.5-3.6-3.3-3.8-3.83.5-3.2-3.1-3.0
Mean num. licks in bursts1.21.85.62.4-2.1-1.7-1.7-0.9-0.7-0.80.9-1.10.10.3
Cd content in liver0.30.30.7-0.2-0.1-0.1-0.5-0.6-0.5-0.50.6-0.8-0.7-0.8
Co content in liver2.83.34.71.6-2.1-1.8-2.1-1.7-1.8-1.91.8-2.2-1.4-1.4
Cu content in liver2.12.43.31.1-1.4-1.5-1.6-1.8-1.5-1.61.6-1.6-1.7-1.6
Fe content in liver0.00.00.0-0.10.00.1-0.10.0-0.0-0.20.0-0.10.00.0
K content in liver0.40.40.8-0.10.1-0.2-0.3-0.4-0.9-0.90.7-0.1-0.8-0.9
Mg content in liver0.10.10.20.30.0-0.3-0.0-0.2-0.2-0.30.20.5-0.1-0.1
Mn content in liver2.73.04.2-1.51.91.71.91.81.72.1-1.81.71.51.5
Na content in liver0.20.20.80.9-0.6-0.6-0.6-0.40.10.1-0.10.10.30.5
Rb content in liver0.30.30.90.8-0.9-0.6-0.9-0.5-0.2-0.10.2-0.9-0.0-0.0
Se content in liver3.94.67.5-2.72.72.72.42.22.02.2-1.91.51.51.2
Sr content in liver1.00.92.00.00.40.30.90.51.11.4-1.11.40.91.1
Zn content in liver1.82.04.12.0-1.6-2.0-1.3-1.6-1.1-1.41.2-0.3-1.1-0.8
Bone: minimum diameter2.64.86.71.3-1.7-1.9-2.3-2.4-2.6-2.22.3-2.3-2.4-2.4
Time in familiar zone, hab. session 10.20.20.40.2-0.3-0.4-0.5-0.6-0.5-0.40.6-0.3-0.5-0.5
Time in novel zone, hab. session 10.10.10.3-0.60.40.50.20.30.30.10.0-0.40.0-0.1
Total zone transitions, hab. session 10.50.61.7-0.10.40.40.20.70.81.0-0.80.81.21.3
Total locomotion distance, hab. session 11.11.63.7-0.4-0.0-0.4-0.9-1.1-1.6-1.41.7-1.1-1.8-1.9
Locomotion velocity, hab. session 10.91.22.7-0.3-0.0-0.4-0.7-0.9-1.5-1.31.4-0.7-1.6-1.7
Time in familiar zone, hab. session 22.22.33.71.7-1.9-1.6-1.8-1.3-1.3-1.31.7-1.7-1.0-1.0
Time in novel zone, hab. session 21.71.73.9-1.01.51.11.71.11.21.0-1.42.01.01.0
Total zone transitions, hab. session 20.40.51.51.2-0.7-0.7-0.9-0.0-0.10.20.10.30.81.1
Total locomotion distance, hab. session 22.83.77.00.6-0.9-1.4-1.8-1.7-2.7-2.42.6-1.4-2.2-2.2
Locomotion velocity, hab. session 23.04.07.70.5-0.8-1.4-1.9-1.8-2.8-2.52.6-1.4-2.4-2.3
Novel to familiar place preference ratio1.21.33.20.4-0.8-0.5-1.4-0.4-1.5-1.41.5-1.8-0.7-0.8
Novelty place preference1.21.32.90.4-0.8-0.5-1.4-0.4-1.6-1.41.5-1.7-0.7-0.8
Time in novel zone, NPP test1.41.53.30.6-0.9-0.7-1.6-0.4-1.7-1.51.6-1.8-0.7-0.9
Total zone transitions, NPP test0.60.82.90.10.50.20.70.60.80.6-1.31.71.01.2
Total locomotion distance, NPP test0.70.92.3-0.40.5-0.40.1-0.8-1.3-1.30.80.6-1.5-1.5
Locomotion velocity, NPP test0.60.81.9-0.70.9-0.10.4-0.6-1.0-1.00.60.9-1.4-1.3
Intraocular pressure1.62.36.1-0.20.30.91.31.02.51.9-2.30.91.71.7
Delta distance traveled before/after self-admin0.50.61.41.2-1.0-0.5-1.00.20.30.00.0-0.61.01.1
Delta ambulatory time before/after self-admin0.40.61.51.1-0.8-0.3-0.70.40.60.4-0.3-0.31.21.2
Parametrial fat weight0.81.83.8-1.41.61.11.90.51.41.3-1.71.90.40.5
Pavlov. Cond. lever latency0.81.12.3-1.51.51.31.21.00.80.9-0.70.90.50.3
Pavlov. Cond. magazine entry latency2.02.65.92.4-2.2-2.2-1.8-1.7-1.3-1.31.4-1.0-0.8-0.5
Pavlov. Cond. change in total contacts1.31.43.01.6-1.7-1.3-1.5-1.0-0.9-0.71.1-1.5-0.5-0.4
Pavlov. Cond. index score1.72.14.82.2-2.1-2.0-1.7-1.5-1.1-1.11.1-1.0-0.7-0.5
Pavlov. Cond. latency score1.72.14.62.1-2.1-1.9-1.7-1.4-1.1-1.21.1-1.1-0.7-0.5
Pavlov. Cond. lever contacts0.80.92.11.4-1.4-1.3-1.1-1.0-0.6-0.70.7-0.7-0.5-0.3
Pavlov. Cond. magazine entry number2.12.66.0-2.52.32.21.91.61.11.2-1.31.30.70.5
Pavlov. Cond. intertrial magazine entries0.40.51.3-1.11.01.10.50.80.40.9-0.40.20.40.3
Pavlov. Cond. lever-magazine prob. diff.1.31.63.92.0-1.9-1.7-1.5-1.3-0.8-0.90.9-0.9-0.5-0.3
Pavlov. Cond. response bias0.91.12.71.6-1.4-1.5-1.2-1.1-0.7-0.70.8-0.6-0.5-0.3
Pavlov. Cond. lever latency10.113.733.1-5.85.25.14.23.63.03.3-2.91.81.50.8
Pavlov. Cond. magazine entry latency1.11.45.52.3-1.5-1.9-0.8-0.9-0.6-0.80.51.00.10.5
Pavlov. Cond. change in total contacts6.610.625.65.1-4.4-4.5-3.9-3.1-2.6-2.92.7-1.5-1.1-0.5
Pavlov. Cond. index score6.89.123.74.9-4.2-4.3-3.3-2.9-2.5-2.72.3-1.0-1.1-0.5
Pavlov. Cond. latency score5.57.320.34.5-3.8-3.9-2.9-2.6-2.1-2.42.0-0.6-0.9-0.3
Pavlov. Cond. lever contacts10.013.831.95.6-5.1-5.0-4.3-3.6-3.1-3.43.0-2.0-1.6-0.9
Pavlov. Cond. magazine entry number2.22.810.2-3.22.42.61.61.30.91.1-0.9-0.4-0.0-0.5
Pavlov. Cond. intertrial magazine entries1.42.23.70.6-1.2-1.1-1.6-1.5-1.4-1.51.6-1.9-1.6-1.7
Pavlov. Cond. lever-magazine prob. diff.6.89.022.44.7-4.1-4.2-3.3-2.9-2.5-2.82.4-1.0-1.2-0.6
Pavlov. Cond. response bias9.112.331.65.6-4.9-4.9-3.9-3.3-2.8-3.12.7-1.4-1.3-0.6
Time in closed arm before self-admin0.40.51.41.2-0.8-0.5-0.90.4-0.30.20.3-0.01.01.2
Time in closed arm after self-admin0.70.71.5-1.21.01.20.71.20.61.0-0.60.40.70.5
Time in open arm before self-admin2.93.27.5-2.42.42.02.71.21.91.1-1.71.70.40.2
Time in open arm after self-admin0.30.30.90.5-0.6-0.7-0.3-1.0-0.2-0.60.3-0.4-0.7-0.7
Bone: periosteal estimation1.53.14.11.7-2.0-2.0-1.9-2.0-1.7-1.41.4-1.8-1.6-1.5
Bone: periosteal perimeter1.52.53.71.7-1.8-1.9-1.7-1.9-1.6-1.31.3-1.2-1.5-1.3
Bone: post-yield work0.10.20.30.3-0.4-0.3-0.5-0.3-0.4-0.60.4-0.6-0.3-0.3
Progressive ratio test 1 active lever presses0.20.30.7-0.00.10.40.20.60.50.6-0.7-0.20.90.9
Progressive ratio test 1 breakpoint0.20.30.7-0.00.10.40.20.50.50.6-0.7-0.20.80.8
Progressive ratio test 1 inactive lever presses0.20.20.6-0.10.30.40.30.60.50.8-0.5-0.10.70.6
Progressive ratio test 2 active lever presses0.20.30.80.9-0.8-0.7-0.6-0.5-0.20.3-0.0-0.6-0.00.1
Progressive ratio test 2 breakpoint0.30.30.80.9-0.8-0.7-0.6-0.5-0.20.3-0.0-0.60.00.1
Progressive ratio test 2 inactive lever presses0.10.20.60.5-0.0-0.10.10.40.10.8-0.30.30.60.7
Incentive Sensitization - Responses0.50.71.51.2-1.1-1.2-1.0-1.0-0.7-0.20.5-0.7-0.6-0.5
Incentive Sensitization - Breakpoint0.40.51.21.1-0.9-1.0-0.8-0.8-0.60.00.4-0.4-0.4-0.3
Sum of active levers in priming session hrs 5-60.10.10.2-0.10.10.2-0.10.4-0.3-0.40.20.50.30.4
Progressive ratio0.40.61.20.50.1-0.10.40.30.71.1-0.91.10.91.1
Food seeking constrained by brief footshock1.61.93.01.5-1.5-1.7-1.3-1.7-1.6-1.21.5-0.7-1.3-1.1
Seeking ratio, punishment vs. effort2.23.24.81.0-1.4-1.6-1.6-1.9-2.0-2.22.1-1.5-2.0-2.0
Retroperitoneal fat weight0.62.68.1-2.01.50.30.4-1.4-1.4-1.31.2-0.4-2.7-2.8
Reaction time number correct0.30.61.3-0.20.50.60.51.10.60.7-0.30.71.11.1
Reaction time mean minus median0.51.21.91.1-1.1-1.3-1.1-1.1-1.4-1.21.1-0.9-1.0-0.9
Reaction time mean minus median AUC0.30.81.61.3-1.1-1.1-1.0-0.6-1.0-1.00.9-0.7-0.4-0.4
Reaction time num false alarms0.50.72.4-1.61.10.90.50.2-0.4-0.50.0-0.3-0.8-1.1
Reaction time num false alarms AUC0.30.41.5-1.20.90.90.70.4-0.1-0.3-0.3-0.0-0.5-0.7
Reaction time trials correct on left0.30.61.3-0.20.50.60.51.10.60.7-0.30.71.11.1
Reaction time trials on left0.30.61.3-0.20.50.60.51.10.60.7-0.40.71.21.1
Reaction time mean0.40.71.8-0.80.30.2-0.1-0.2-1.1-1.00.9-0.6-1.1-1.4
Reaction time mean AUC0.30.41.0-1.00.60.50.10.1-0.7-0.60.7-0.4-0.7-1.0
Median of all reaction times0.40.61.6-1.30.80.70.40.2-0.7-0.60.6-0.3-0.8-1.1
Reaction time omissions0.20.30.7-0.10.1-0.2-0.2-0.5-0.8-0.70.5-0.4-0.8-0.9
Reaction time false alarm rate0.40.51.5-1.20.70.60.6-0.1-0.4-0.6-0.1-0.1-1.0-1.2
Reaction time premature initiation rate2.94.06.11.8-2.2-2.2-1.7-2.5-2.1-2.11.7-1.3-2.2-2.0
Reaction time premature initiations1.01.72.81.5-1.6-1.7-1.1-1.5-1.4-1.31.1-0.6-1.2-1.0
Std. dev. reaction times1.32.43.80.7-1.2-1.3-1.4-1.6-1.9-1.71.6-1.6-1.9-1.9
Reaction time trials completed0.30.61.3-0.20.50.60.51.10.60.7-0.40.71.21.1
Reaction time trials AUC0.20.30.8-0.10.30.40.40.90.40.5-0.10.50.90.8
Run reversals in cocaine runway, females2.32.34.90.2-0.6-1.1-1.1-2.0-1.6-1.61.8-0.8-2.2-2.1
Run reversals in cocaine runway, males0.40.41.3-0.40.30.60.40.50.91.1-0.90.30.60.5
Latency to leave start box in cocaine runway0.60.72.8-1.71.11.01.0-0.00.30.7-0.30.3-0.6-0.7
Latency to leave start box in cocaine runway, F0.60.72.2-1.40.50.50.2-0.6-0.6-0.30.6-0.6-1.4-1.5
Latency to leave start box in cocaine runway, M1.31.22.2-0.81.00.91.50.81.21.3-1.21.50.80.8
Std. dev. time between licks in bursts4.05.47.71.6-2.0-2.2-2.1-2.4-2.7-2.82.3-2.0-2.6-2.6
Total sessions with >9 infusions1.21.44.52.1-1.8-1.7-1.4-1.1-0.7-0.40.7-1.0-0.2-0.0
Short access day 1 total inactive lever presses0.10.10.20.4-0.4-0.4-0.3-0.2-0.5-0.00.1-0.4-0.1-0.2
Short access day 10 total inactive lever presses0.20.41.1-1.10.91.00.90.80.30.4-0.30.20.2-0.0
Short access day 1 total infusions2.73.67.02.6-2.6-2.4-2.2-1.8-1.6-1.51.5-1.6-1.0-0.9
Short access day 10 total infusions1.01.23.51.9-1.7-1.6-1.4-1.1-0.7-0.50.6-0.9-0.2-0.0
Short access total infusions1.21.54.72.2-1.9-1.7-1.4-1.0-0.7-0.40.5-1.0-0.10.1
Short access day 1 locomotion0.60.72.31.5-1.0-0.8-0.50.00.80.8-0.7-0.21.01.1
Short access day 10 total locomotion0.30.61.91.4-0.9-1.2-0.9-0.7-0.6-0.80.5-0.1-0.20.0
Short access total locomotion0.30.31.00.6-0.3-0.20.00.30.70.7-0.70.20.91.0
One hour access (0.3 mA shock)0.30.41.71.3-0.9-1.0-0.4-0.4-0.2-0.3-0.2-0.20.10.3
Compulsive drug intake2.93.44.5-1.51.72.01.82.12.12.1-2.01.41.91.8
One hour access (shock baseline)0.91.34.02.0-1.5-1.8-1.1-1.1-1.1-0.90.7-0.2-0.5-0.2
Social response proportion0.40.41.1-0.50.6-0.00.6-0.3-0.8-0.60.30.5-1.0-1.0
Social responses1.41.84.1-0.1-0.0-0.6-0.6-1.1-1.9-1.81.4-1.0-1.9-2.0
Social time1.52.05.1-2.12.31.91.61.60.61.1-0.91.00.80.6
Soleus weight0.82.56.9-0.0-0.4-1.0-0.6-1.8-1.8-1.61.5-0.9-2.5-2.6
Bone: stiffness0.40.72.1-0.6-0.00.2-0.5-0.2-1.0-1.00.7-1.4-1.0-1.2
Tibialis anterior weight0.41.42.30.5-0.8-1.0-1.1-1.2-1.5-1.31.2-1.3-1.5-1.5
Time to tail flick, vehicle, before self-admin0.10.10.30.5-0.1-0.4-0.5-0.2-0.3-0.10.1-0.00.30.4
Time to tail flick, vehicle, after self-admin0.50.62.01.4-1.4-0.9-0.9-0.4-0.1-0.20.0-0.80.20.3
Time to tail flick, test, before self-admin1.92.03.41.2-1.5-1.4-1.8-1.6-1.3-1.41.4-1.7-1.0-0.9
Time to tail flick, test, after self-admin2.52.63.41.0-1.5-1.4-1.8-1.6-1.8-1.61.8-1.7-1.7-1.7
Delta time to tail flick, vehicle, before/after SA0.20.20.70.7-0.9-0.4-0.1-0.10.50.2-0.3-0.30.20.1
Delta time to tail flick, test, before/after SA0.30.30.7-0.80.80.60.80.50.30.4-0.30.8-0.1-0.2
Tibia length0.41.23.71.9-1.9-1.1-1.3-0.0-0.3-0.80.3-0.80.80.8
Ambulatory time before self-admin0.50.71.7-1.31.21.10.90.90.30.3-0.51.00.30.3
Ambulatory time after self-admin1.31.53.6-0.50.81.10.61.71.11.0-1.01.21.81.9
Bone: tissue strength3.13.23.9-1.11.61.61.81.81.91.9-1.82.01.91.9
Total heroin consumption0.10.10.40.10.1-0.1-0.40.1-0.6-0.40.60.40.00.1
Bone: trabecular number1.62.63.6-1.61.81.71.61.51.81.7-1.91.31.41.4
Bone: trabecular spacing0.20.31.11.0-0.5-0.80.1-0.2-0.1-0.2-0.21.10.20.4
Bone: trabecular thickness0.50.72.6-0.6-0.10.3-0.9-0.1-0.8-0.71.1-1.6-0.6-0.8
Bone: trabecular tissue density1.62.45.4-1.00.10.1-1.0-0.8-2.0-1.81.8-2.0-2.0-2.3
Water consumed over 24 hours0.30.30.7-0.70.70.70.40.50.60.4-0.90.20.50.4
Number of responses in last shaping day0.50.51.5-0.3-0.4-0.1-0.3-0.5-0.8-0.60.4-1.2-1.0-1.2