Hub : Genes

Nup98

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Nup98 0.17 0.11 3.9e-09 0.05 0.07 0.07 0.07 7.6e-06 1.3e-08 3.4e-08 2.0e-08
2 Liver intron excision ratio chr1_165987936_166003238 0.02 0.02 7.3e-03 0 0 -0 -0 2.1e-01 1.4e-01 8.8e-01 4.8e-01
3 PL mRNA stability Nup98 0.04 0.03 1.7e-04 0.01 0.03 0.02 0.02 1.1e-02 5.1e-04 4.6e-03 7.0e-03
4 Adipose gene expression Nup98 0.25 0.14 0.0e+00 0.15 0.16 0.14 0.16 1.7e-16 4.0e-17 1.4e-15 2.1e-17
5 IC mRNA stability Nup98 0.2 0.1 9.7e-07 0.13 0.13 0.11 0.12 5.4e-06 5.0e-06 2.2e-05 6.8e-06
6 Liver intron excision ratio chr1_165987936_166002959 0.03 0.02 2.7e-03 0.01 0.01 0.01 0.01 9.3e-03 2.5e-02 3.1e-02 2.7e-02
7 NAcc mRNA stability Nup98 0.1 0.06 1.2e-11 0.08 0.08 0.08 0.08 1.3e-12 1.6e-12 1.7e-12 1.6e-12
8 pVTA mRNA stability Nup98 0.06 0.05 1.9e-04 0.06 0.04 0.05 0.05 6.3e-06 1.5e-04 1.0e-04 7.4e-05
9 BLA mRNA stability Nup98 0.19 0.11 1.9e-08 0.14 0.13 0.14 0.13 4.7e-08 1.4e-07 9.2e-08 1.9e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.10.20.5-0.70.5-0.50.5-0.40.30.30.30.3
Area under the delay curve0.10.21.2-1.10.00.0-0.10.2-0.4-0.4-0.4-0.4
BMI with tail1.24.15.41.11.7-1.81.8-2.32.32.22.32.3
BMI without tail0.21.16.02.50.1-0.20.2-0.60.90.90.90.9
Body weight0.10.62.21.5-0.90.8-0.90.5-0.4-0.6-0.5-0.4
Weight adjusted by age0.20.51.21.1-0.90.9-0.80.7-0.5-0.3-0.5-0.4
Bone surface0.61.11.40.5-1.11.1-1.21.2-1.2-1.0-1.0-1.0
Bone volume0.30.70.90.2-0.80.8-0.90.9-0.9-0.8-0.8-0.8
Breakpoint value in progressive ratio session0.61.11.5-0.81.2-1.21.0-1.10.80.91.01.0
Number of licking bursts0.61.74.8-2.21.5-1.41.2-1.30.80.80.90.9
Context. condit. distance diff. score0.81.05.82.4-0.90.9-0.80.7-0.3-0.00.00.0
Locomotion velocity, session 12.52.93.7-0.11.7-1.71.7-1.81.71.91.91.9
Locomotion distance, session 10.70.81.61.30.6-0.70.7-0.81.01.01.01.0
Locomotion velocity, session 21.01.21.60.71.0-1.00.9-1.11.11.21.21.2
Locomotion distance, session 20.91.21.51.10.9-0.90.9-1.11.21.21.21.2
Locomotion velocity, session 30.10.20.70.8-0.40.4-0.40.4-0.3-0.1-0.2-0.1
Locomotion distance, session 30.10.11.01.0-0.20.2-0.10.1-0.00.20.20.2
Stereotopy head waving bouts, day 30.50.61.0-0.5-0.60.6-0.60.7-0.7-1.0-0.9-1.0
Stereotopy head waving duration, day 30.10.10.50.7-0.30.2-0.00.20.2-0.3-0.2-0.3
Locomotion velocity, session 71.11.21.70.21.1-1.11.0-1.21.11.31.31.3
Locomotion distance, session 70.10.10.2-0.50.4-0.30.1-0.30.00.30.30.3
Stereotopy head waving bouts, day 71.11.34.32.1-1.21.2-1.01.1-0.6-0.8-0.7-0.7
Stereotopy head waving duration, day 70.91.14.82.2-1.11.1-0.81.0-0.4-0.6-0.5-0.6
Locomotion velocity, session 80.40.52.01.4-0.80.8-0.80.7-0.6-0.1-0.1-0.1
Locomotion distance, session 80.60.96.82.6-0.50.4-0.40.10.20.50.50.5
Degree of sensitization distance0.40.50.8-0.6-0.50.5-0.70.5-0.9-0.7-0.7-0.7
Degree of sensitization stereotypy2.02.27.72.8-1.61.6-1.41.4-0.9-0.9-0.8-0.8
Conditioned locomotion0.30.30.7-0.9-0.20.3-0.50.4-0.8-0.5-0.5-0.5
Cocaine response after cond. corrected0.40.51.6-1.30.8-0.80.8-0.70.50.40.50.4
Cocaine response after cond. not corrected0.71.01.3-0.61.1-1.11.1-1.11.10.91.00.9
Cocaine response before conditioning0.60.72.71.60.2-0.30.5-0.40.90.90.90.9
Saline control response3.04.25.11.2-2.32.3-2.22.2-2.0-2.0-2.0-2.0
Bone: connectivity density1.01.62.0-0.01.3-1.31.3-1.31.31.41.41.4
Bone: cortical apparent density0.20.42.2-1.50.6-0.50.5-0.40.2-0.1-0.1-0.1
Bone: cortical area0.10.20.40.3-0.50.5-0.60.4-0.6-0.3-0.3-0.4
Bone: cortical porosity0.20.20.3-0.3-0.30.3-0.30.5-0.5-0.5-0.5-0.5
Bone: cortical porosity0.20.30.4-0.1-0.50.5-0.40.6-0.5-0.6-0.6-0.5
Bone: cortical thickness0.91.51.9-0.51.4-1.41.3-1.41.21.31.31.2
Bone: cortical thickness0.00.00.10.2-0.10.1-0.20.1-0.2-0.3-0.3-0.3
Bone: cortical tissue density0.20.42.3-1.50.6-0.60.5-0.50.2-0.1-0.1-0.1
Condit. Reinf. active minus inactive responses2.22.52.90.3-1.71.7-1.61.7-1.6-1.7-1.7-1.6
Condit. Reinf. active-inactive response ratio4.14.45.30.3-2.22.3-2.22.3-2.2-2.2-2.2-2.2
Condit. Reinf. active responses1.11.41.8-0.4-1.11.2-1.11.2-1.2-1.4-1.4-1.3
Condit. Reinf. inactive responses0.30.30.5-0.70.7-0.70.7-0.60.50.40.40.4
Incentive salience index mean1.31.72.2-0.0-1.31.3-1.21.4-1.2-1.4-1.5-1.4
Condit. Reinf. lever presses0.00.00.1-0.0-0.10.10.00.10.1-0.2-0.2-0.2
Condit. Reinf. active minus inactive responses4.87.39.43.0-3.13.0-3.02.8-2.4-2.2-2.3-2.3
Condit. Reinf. active-inactive response ratio0.40.61.81.3-0.90.9-0.80.8-0.6-0.5-0.5-0.5
Condit. Reinf. active responses7.811.214.33.4-3.83.7-3.73.5-3.1-2.9-3.0-2.9
Condit. Reinf. inactive responses4.56.78.42.1-2.92.9-2.92.7-2.5-2.4-2.4-2.4
Condit. Reinf. lever presses7.010.122.44.7-3.63.5-3.43.1-2.5-2.3-2.3-2.3
Condit. Reinf. lever reinforcers received8.211.514.73.5-3.83.8-3.73.5-3.1-2.9-3.0-2.9
Conditioned reinforcement - actives0.00.00.10.30.2-0.20.1-0.10.10.30.20.2
Conditioned reinforcement - inactives0.10.32.0-1.4-0.10.1-0.10.2-0.4-0.3-0.4-0.5
Conditioned locomotion0.40.71.11.00.5-0.50.6-0.50.80.91.01.0
Patch foraging indifference point 0 sec0.41.24.52.1-1.21.1-1.00.9-0.5-0.8-0.8-0.7
Patch foraging indifference point AUC0.30.71.10.6-0.80.8-0.80.8-0.7-0.8-1.0-1.0
Delay disc. indifference point, 0s delay0.50.61.01.0-0.90.8-0.90.7-0.6-0.6-0.5-0.6
Delay disc. indifference point, 16s delay0.60.81.8-1.4-0.40.5-0.50.7-0.9-1.1-1.0-1.0
Delay disc. indifference point, 2s delay1.01.11.40.2-1.11.1-1.11.1-1.1-1.1-1.2-1.2
Delay disc. indifference point, 24s delay0.30.53.5-1.90.4-0.30.2-0.1-0.2-0.3-0.2-0.3
Delay disc. indifference point, 4s delay1.61.72.20.6-1.41.4-1.51.4-1.3-1.3-1.4-1.4
Delay disc. indifference point, 8s delay0.10.10.8-0.90.4-0.40.2-0.2-0.0-0.1-0.1-0.0
Indifference point function ln k0.00.10.30.40.1-0.10.3-0.10.40.40.50.5
Indifference point function log k0.00.10.30.40.1-0.10.3-0.10.40.40.50.5
Patch foraging total patch changes 0 sec0.30.94.42.1-1.00.9-0.80.7-0.3-0.6-0.6-0.5
Patch foraging total patch changes 12 sec1.01.41.81.1-1.21.2-1.31.1-1.1-1.1-1.3-1.2
Patch foraging total patch changes 18 sec0.41.01.81.4-1.01.0-1.00.9-0.8-0.9-1.0-0.9
Patch foraging total patch changes 24 sec0.51.62.21.2-1.41.4-1.51.2-1.2-1.1-1.2-1.2
Patch foraging total patch changes 6 sec0.40.62.21.5-0.80.8-0.60.6-0.1-0.5-0.7-0.6
Patch foraging time to switch 0 sec0.62.26.8-2.61.7-1.61.4-1.30.80.91.01.0
Patch foraging water rate 0 sec0.51.85.22.3-1.61.5-1.31.3-0.8-0.8-1.0-1.0
Patch foraging water rate 12 sec0.41.65.92.40.4-0.50.6-0.91.31.41.31.3
Patch foraging water rate 18 sec0.40.96.02.4-0.80.7-0.70.5-0.10.00.00.0
Patch foraging water rate 24 sec0.60.81.31.10.6-0.70.8-0.81.11.10.91.0
Patch foraging water rate 6 sec0.50.82.01.40.4-0.50.6-0.60.91.11.01.0
Seeking ratio, delayed vs. immediate footshock1.62.32.9-1.51.6-1.61.7-1.51.41.41.41.4
Distance traveled before self-admin0.61.32.2-0.11.1-1.11.1-1.21.11.51.41.4
Distance traveled after self-admin1.62.84.40.41.5-1.51.6-1.61.82.12.02.0
Extensor digitorum longus weight0.10.20.3-0.40.6-0.50.3-0.60.20.40.50.4
Bone: elastic displacement2.33.03.7-1.01.8-1.81.9-1.81.81.71.71.7
Bone: elastic work4.66.17.1-1.12.7-2.62.7-2.62.62.52.52.5
Bone: endosteal estimation1.74.15.60.9-2.12.1-2.42.1-2.3-1.9-1.9-1.9
Bone: endosteal perimeter1.74.15.51.4-2.32.2-2.32.2-2.1-1.8-1.8-1.8
Epididymis fat weight0.10.70.9-0.61.0-0.90.8-1.00.80.80.70.8
Delta time in closed arm before/after self-admin0.20.21.5-1.20.3-0.30.2-0.2-0.0-0.1-0.1-0.1
Delta time in open arm before/after self-admin2.32.73.81.4-1.91.9-1.81.8-1.5-1.6-1.4-1.4
Diff in mean of infusions in LGA sessions0.61.06.2-2.5-0.20.3-0.30.5-0.8-0.9-0.8-0.8
Delay discount exponential model param0.10.21.21.1-0.20.2-0.1-0.00.20.20.30.3
Extinction: sum of active levers before priming0.10.10.1-0.0-0.30.3-0.30.4-0.3-0.3-0.4-0.4
Active lever presses in extinction session 60.60.61.51.20.3-0.30.6-0.51.00.71.01.0
Bone: final force0.50.81.7-1.3-0.40.5-0.70.7-1.1-0.9-0.9-1.0
Bone: final moment0.40.71.1-1.0-0.50.5-0.70.7-1.0-0.9-0.9-0.9
Food consumed during 24 hour testing period0.30.74.12.0-0.80.7-0.50.6-0.1-0.2-0.2-0.2
Glucose0.30.50.70.30.7-0.70.7-0.80.70.80.80.8
Heart weight0.91.42.11.2-1.41.4-1.41.2-1.0-1.0-0.9-1.0
Delay discount hyperbolic model param0.10.20.91.0-0.0-0.00.1-0.20.40.40.40.4
Intermittent access intake day 1-15 change0.42.43.71.31.0-1.11.3-1.31.81.91.91.9
Intermittent access intake escalation0.31.72.71.50.7-0.81.0-1.01.51.61.61.6
Intermittent access intake escalation 20.30.51.00.70.4-0.50.5-0.60.71.00.90.9
Intermitt. access day 1 inactive lever presses0.00.54.1-2.00.5-0.40.3-0.3-0.0-0.1-0.1-0.1
Intermitt. access day 15 inactive lever presses0.00.10.5-0.70.1-0.10.3-0.20.30.40.40.4
Intermitt. access escalation Index0.00.10.2-0.1-0.40.4-0.30.4-0.3-0.4-0.4-0.4
Intermittent access day 1 total infusions0.30.91.20.7-1.01.0-1.01.1-1.0-0.8-0.9-0.9
Intermittent access day 15 total infusions0.10.21.11.0-0.40.3-0.20.3-0.00.30.20.2
Intermittent access terminal intake (last 3 days)0.20.31.11.1-0.60.6-0.60.6-0.4-0.1-0.2-0.2
Intermittent access total infusions0.20.31.11.0-0.50.5-0.50.5-0.4-0.3-0.3-0.3
Intermittent access day 1 locomotion0.20.40.6-0.3-0.60.6-0.50.8-0.7-0.7-0.6-0.7
Intermittent access day 15 total locomotion0.20.60.90.40.6-0.70.9-0.60.90.80.90.9
Intermittent access total locomotion0.10.10.30.5-0.40.4-0.20.4-0.2-0.2-0.1-0.1
Intermittent access standard deviation0.10.50.80.60.4-0.50.5-0.70.90.80.90.9
Left kidney weight0.00.31.51.2-0.60.5-0.50.2-0.1-0.2-0.1-0.1
Right kidney weight0.21.32.11.3-1.51.4-1.31.1-0.9-1.0-0.9-0.8
Cocaine induced anxiety0.30.85.9-2.40.7-0.60.6-0.40.1-0.30.00.0
Post-drug Anxiety1.01.13.8-1.9-0.40.5-0.40.8-1.0-1.3-1.1-1.1
Baseline Anxiety1.83.03.71.2-1.91.9-1.81.9-1.6-1.6-1.8-1.8
Tail length2.513.716.31.7-4.04.0-4.04.0-3.7-3.8-3.7-3.7
Length with tail2.711.713.81.5-3.73.7-3.73.6-3.5-3.5-3.5-3.5
Length without tail0.10.50.7-0.0-0.70.7-0.70.7-0.7-0.8-0.8-0.8
Times rat made contact with spout0.10.10.4-0.7-0.10.1-0.20.2-0.3-0.4-0.3-0.4
Lifetime Intake0.30.41.71.3-0.70.6-0.60.6-0.5-0.2-0.3-0.3
Liver weight, left0.20.40.8-0.9-0.30.4-0.60.5-0.9-0.6-0.6-0.6
Liver weight, right0.50.91.5-0.8-0.70.7-1.00.8-1.2-1.1-1.1-1.1
Locomotor activity0.10.21.41.2-0.40.3-0.30.10.10.00.10.1
Locomotor testing distance0.40.93.31.8-1.11.0-1.00.8-0.6-0.5-0.5-0.5
Locomotor testing rearing0.31.11.61.0-1.11.1-1.31.0-1.1-0.9-0.9-0.9
Locomotion in novel chamber1.41.92.4-0.41.3-1.41.5-1.41.61.51.41.4
Locomotion in novel chamber post-restriction0.00.11.01.0-0.00.00.10.00.20.40.30.3
Fecal boli incidents, locomotor time 10.30.73.0-1.70.9-0.90.7-0.60.40.50.50.5
Change in fecal boli incidents, locomotor task0.20.20.40.6-0.40.3-0.30.3-0.2-0.7-0.5-0.5
Time >=10cm from walls, locomotor time 10.70.91.30.6-1.01.0-0.81.0-0.8-1.1-1.1-1.1
Bouts of movement, locomotor time 10.70.91.3-0.4-1.11.1-0.91.1-1.0-1.1-0.9-0.9
Total resting periods, locomotor time 10.10.20.4-0.6-0.40.4-0.20.5-0.4-0.5-0.3-0.4
Rest time, locomotor task time 10.10.20.3-0.4-0.20.3-0.20.4-0.5-0.5-0.4-0.5
Distance moved, locomotor task time 10.00.10.20.20.3-0.30.2-0.40.30.40.40.3
Vertical activity count, locomotor time 10.00.00.1-0.2-0.10.1-0.20.1-0.1-0.3-0.2-0.3
Time >=10cm from walls, locomotor time 21.85.05.91.2-2.42.4-2.32.4-2.1-2.3-2.3-2.4
Bouts of movement, locomotor time 21.03.24.5-0.6-1.71.7-1.81.9-2.1-2.0-1.9-1.9
Total resting periods, locomotor time 20.51.92.8-1.0-1.11.2-1.31.4-1.7-1.6-1.5-1.4
Rest time, locomotor task time 20.91.62.5-1.61.5-1.51.3-1.40.91.01.01.0
Distance moved, locomotor task time 21.11.52.71.6-1.41.3-1.21.2-0.9-1.0-1.0-1.1
Vertical activity count, locomotor time 20.51.11.70.1-1.01.0-1.11.1-1.1-1.3-1.2-1.3
Light reinforcement 10.94.15.1-1.22.3-2.22.0-2.31.92.12.02.0
Light reinforcement 22.45.36.90.82.2-2.22.3-2.42.52.62.62.6
Bone: marrow area1.53.65.00.7-2.02.0-2.22.0-2.2-1.8-1.8-1.8
Bone: maximum diameter1.53.14.31.5-1.91.9-2.11.8-1.8-1.5-1.5-1.5
Bone: maximum force0.10.20.8-0.9-0.10.2-0.40.3-0.7-0.4-0.4-0.4
Bone: maximum moment0.10.10.4-0.5-0.10.2-0.40.3-0.6-0.2-0.3-0.3
Mean time between licks in bursts1.811.013.11.7-3.63.6-3.63.5-3.3-3.4-3.3-3.4
Mean num. licks in bursts0.61.73.81.9-1.51.5-1.21.4-0.9-1.0-1.0-1.0
Cd content in liver0.40.40.7-0.7-0.40.4-0.50.6-0.8-0.6-0.7-0.7
Co content in liver3.13.64.20.7-2.02.0-2.02.0-1.9-2.0-2.0-2.0
Cu content in liver1.92.22.60.3-1.61.6-1.61.6-1.6-1.6-1.6-1.6
Fe content in liver0.00.00.1-0.3-0.10.1-0.00.1-0.1-0.2-0.2-0.2
K content in liver0.10.10.4-0.60.2-0.20.2-0.20.1-0.0-0.0-0.0
Mg content in liver0.20.20.30.40.3-0.30.4-0.40.60.40.40.4
Mn content in liver2.83.13.8-1.01.9-1.91.9-1.91.71.91.81.8
Na content in liver0.10.11.01.0-0.10.1-0.00.10.20.20.30.3
Rb content in liver0.50.60.8-0.2-0.70.8-0.60.9-0.8-0.8-0.9-0.9
Se content in liver3.23.77.2-2.72.2-2.22.0-1.91.41.51.61.6
Sr content in liver1.31.21.61.20.8-0.80.9-1.01.31.21.21.2
Zn content in liver0.80.93.51.9-1.01.0-0.90.8-0.4-0.5-0.6-0.6
Bone: minimum diameter1.52.94.00.4-1.71.8-2.01.8-2.0-1.7-1.7-1.7
Time in familiar zone, hab. session 10.10.10.30.6-0.20.1-0.30.1-0.20.00.00.0
Time in novel zone, hab. session 10.20.20.6-0.8-0.20.3-0.20.3-0.4-0.5-0.5-0.5
Total zone transitions, hab. session 10.20.30.60.60.4-0.40.4-0.40.50.80.80.7
Total locomotion distance, hab. session 10.71.01.5-0.4-0.80.9-1.00.8-1.0-1.2-1.2-1.2
Locomotion velocity, hab. session 10.30.50.8-0.4-0.50.6-0.70.5-0.7-0.9-0.9-0.9
Time in familiar zone, hab. session 23.03.44.31.5-2.02.0-2.11.9-1.8-1.8-1.7-1.8
Time in novel zone, hab. session 23.63.94.6-0.62.0-2.02.1-2.12.12.12.12.1
Total zone transitions, hab. session 20.50.74.62.1-0.70.6-0.40.40.10.10.20.1
Total locomotion distance, hab. session 21.21.62.10.8-1.41.4-1.41.2-1.2-1.3-1.3-1.3
Locomotion velocity, hab. session 21.21.62.20.6-1.41.4-1.51.2-1.3-1.3-1.4-1.3
Novel to familiar place preference ratio2.22.93.9-0.5-1.71.7-1.61.8-1.7-1.9-2.0-1.9
Novelty place preference2.12.73.5-0.4-1.61.7-1.61.7-1.7-1.8-1.9-1.8
Time in novel zone, NPP test2.63.14.0-0.3-1.81.8-1.71.9-1.8-1.9-2.0-1.9
Total zone transitions, NPP test1.21.82.50.81.2-1.21.3-1.31.51.51.61.5
Total locomotion distance, NPP test0.20.30.60.00.6-0.60.6-0.80.70.50.50.5
Locomotion velocity, NPP test0.50.71.2-0.20.9-1.00.9-1.10.90.70.70.7
Intraocular pressure0.30.50.8-0.00.6-0.60.9-0.60.90.80.70.7
Delta distance traveled before/after self-admin0.60.60.91.0-0.90.9-0.70.9-0.6-0.7-0.7-0.7
Delta ambulatory time before/after self-admin0.20.40.90.9-0.70.7-0.50.7-0.4-0.4-0.5-0.5
Parametrial fat weight2.15.06.0-0.02.3-2.32.3-2.42.32.42.42.4
Pavlov. Cond. lever latency0.91.11.4-0.51.1-1.11.1-1.21.11.11.21.1
Pavlov. Cond. magazine entry latency1.51.94.52.1-1.61.5-1.41.4-1.0-0.9-1.0-0.9
Pavlov. Cond. change in total contacts2.32.53.10.5-1.61.7-1.61.8-1.6-1.6-1.7-1.7
Pavlov. Cond. index score1.41.72.11.4-1.51.4-1.41.4-1.2-1.1-1.2-1.1
Pavlov. Cond. latency score1.41.82.21.2-1.51.5-1.41.5-1.2-1.2-1.3-1.2
Pavlov. Cond. lever contacts0.70.81.00.7-1.01.0-0.91.0-0.9-0.8-0.9-0.8
Pavlov. Cond. magazine entry number1.72.23.3-1.81.7-1.71.5-1.61.21.11.21.2
Pavlov. Cond. intertrial magazine entries0.20.31.5-1.20.5-0.50.4-0.30.10.10.10.1
Pavlov. Cond. lever-magazine prob. diff.1.21.41.81.3-1.31.3-1.21.3-1.1-1.0-1.1-1.1
Pavlov. Cond. response bias0.60.81.71.3-1.01.0-0.90.9-0.7-0.5-0.6-0.6
Pavlov. Cond. lever latency6.28.730.4-5.53.3-3.13.0-2.61.81.61.71.6
Pavlov. Cond. magazine entry latency1.11.610.43.2-0.1-0.00.1-0.40.91.01.01.0
Pavlov. Cond. change in total contacts3.07.227.05.2-3.02.8-2.62.4-1.5-1.4-1.5-1.4
Pavlov. Cond. index score3.25.024.04.9-2.32.2-2.11.7-1.0-0.9-0.9-0.9
Pavlov. Cond. latency score2.43.921.84.7-2.01.8-1.71.4-0.7-0.5-0.6-0.5
Pavlov. Cond. lever contacts6.08.827.35.2-3.43.2-3.02.7-1.9-1.8-1.9-1.8
Pavlov. Cond. magazine entry number1.52.015.3-3.91.0-0.80.7-0.4-0.2-0.3-0.3-0.3
Pavlov. Cond. intertrial magazine entries1.43.03.9-0.3-1.71.8-1.71.9-1.8-2.0-2.0-2.0
Pavlov. Cond. lever-magazine prob. diff.3.35.023.04.8-2.42.2-2.11.8-1.1-0.9-1.0-1.0
Pavlov. Cond. response bias5.47.530.95.6-3.02.8-2.62.3-1.4-1.3-1.4-1.3
Time in closed arm before self-admin0.40.74.02.0-0.80.8-0.50.6-0.2-0.2-0.2-0.2
Time in closed arm after self-admin0.20.20.7-0.80.4-0.40.5-0.40.30.30.30.3
Time in open arm before self-admin3.44.25.6-2.32.4-2.32.2-2.21.81.71.61.6
Time in open arm after self-admin0.20.20.30.1-0.60.6-0.50.5-0.4-0.6-0.5-0.5
Bone: periosteal estimation0.71.72.60.7-1.41.4-1.61.4-1.6-1.1-1.1-1.1
Bone: periosteal perimeter0.71.32.01.2-1.31.3-1.41.2-1.2-0.9-0.9-0.9
Bone: post-yield work0.10.10.20.4-0.30.3-0.50.2-0.5-0.2-0.2-0.1
Progressive ratio test 1 active lever presses0.00.00.0-0.20.0-0.00.10.1-0.0-0.10.10.0
Progressive ratio test 1 breakpoint0.00.00.0-0.20.00.00.10.1-0.1-0.1-0.0-0.0
Progressive ratio test 1 inactive lever presses0.10.20.8-0.90.5-0.40.5-0.30.20.20.20.2
Progressive ratio test 2 active lever presses0.10.10.20.1-0.30.3-0.20.4-0.4-0.2-0.3-0.3
Progressive ratio test 2 breakpoint0.10.10.10.2-0.30.3-0.20.4-0.4-0.2-0.3-0.3
Progressive ratio test 2 inactive lever presses0.00.10.20.00.3-0.30.4-0.30.30.50.40.4
Incentive Sensitization - Responses0.10.20.20.4-0.30.3-0.40.4-0.5-0.3-0.4-0.4
Incentive Sensitization - Breakpoint0.00.00.20.4-0.10.1-0.20.2-0.20.0-0.1-0.2
Sum of active levers in priming session hrs 5-60.10.10.40.60.1-0.20.1-0.20.30.50.30.3
Progressive ratio0.31.01.61.20.6-0.60.7-0.81.11.31.21.2
Food seeking constrained by brief footshock1.41.82.71.6-1.61.5-1.31.3-1.0-1.1-1.1-1.1
Seeking ratio, punishment vs. effort1.02.23.10.4-1.41.4-1.51.5-1.6-1.8-1.7-1.7
Retroperitoneal fat weight0.31.32.4-1.51.4-1.31.1-1.30.80.90.90.9
Reaction time number correct0.10.30.40.20.5-0.50.6-0.50.60.60.50.4
Reaction time mean minus median0.10.71.00.6-1.01.0-1.00.9-0.9-0.8-0.8-0.7
Reaction time mean minus median AUC0.10.40.60.6-0.70.7-0.80.7-0.6-0.7-0.5-0.5
Reaction time num false alarms0.40.75.0-2.20.5-0.50.4-0.3-0.1-0.3-0.3-0.3
Reaction time num false alarms AUC0.30.74.4-2.10.8-0.70.6-0.50.10.0-0.0-0.0
Reaction time trials correct on left0.10.30.40.20.5-0.50.6-0.50.60.60.50.4
Reaction time trials on left0.10.30.50.20.6-0.60.7-0.60.70.70.60.5
Reaction time mean0.30.63.8-1.90.00.0-0.20.2-0.7-0.8-0.6-0.6
Reaction time mean AUC0.30.74.6-2.10.2-0.1-0.10.1-0.6-0.7-0.5-0.5
Median of all reaction times0.50.85.9-2.40.5-0.40.2-0.1-0.5-0.5-0.3-0.3
Reaction time omissions0.10.10.4-0.60.4-0.40.4-0.40.30.10.20.2
Reaction time false alarm rate0.40.64.0-2.00.7-0.60.5-0.40.0-0.0-0.00.0
Reaction time premature initiation rate1.62.43.21.4-1.81.7-1.81.6-1.5-1.3-1.5-1.4
Reaction time premature initiations0.30.91.61.3-1.11.0-1.10.9-0.8-0.6-0.8-0.7
Std. dev. reaction times0.51.72.5-0.7-1.21.2-1.31.3-1.6-1.5-1.4-1.4
Reaction time trials completed0.10.30.50.20.6-0.60.7-0.60.70.70.60.5
Reaction time trials AUC0.00.20.20.20.4-0.40.5-0.40.50.50.40.3
Run reversals in cocaine runway, females0.60.60.80.7-0.90.8-0.90.7-0.7-0.9-0.8-0.8
Run reversals in cocaine runway, males0.20.20.8-0.90.5-0.50.5-0.40.30.20.40.4
Latency to leave start box in cocaine runway0.30.42.6-1.60.7-0.70.3-0.5-0.1-0.2-0.1-0.1
Latency to leave start box in cocaine runway, F0.70.92.7-1.6-0.10.1-0.60.3-0.9-1.1-1.1-1.1
Latency to leave start box in cocaine runway, M1.41.41.8-0.51.4-1.31.2-1.31.11.11.21.2
Std. dev. time between licks in bursts2.24.15.00.5-2.12.1-2.22.1-2.2-2.2-2.1-2.1
Total sessions with >9 infusions0.60.72.31.5-0.80.8-0.90.8-0.7-0.4-0.5-0.5
Short access day 1 total inactive lever presses0.20.40.6-0.7-0.40.5-0.60.6-0.8-0.7-0.7-0.8
Short access day 10 total inactive lever presses0.10.53.0-1.70.6-0.60.5-0.50.20.0-0.0-0.0
Short access day 1 total infusions1.22.53.41.5-1.71.7-1.81.6-1.6-1.2-1.4-1.4
Short access day 10 total infusions0.30.51.81.4-0.70.6-0.80.6-0.6-0.3-0.4-0.3
Short access total infusions0.71.02.41.5-1.11.1-1.11.1-0.9-0.5-0.7-0.6
Short access day 1 locomotion0.10.20.91.0-0.20.2-0.10.10.10.40.30.3
Short access day 10 total locomotion0.00.10.90.9-0.0-0.00.1-0.10.30.20.30.3
Short access total locomotion0.10.20.30.40.3-0.30.4-0.30.40.50.60.6
One hour access (0.3 mA shock)0.10.20.70.90.1-0.10.2-0.20.30.50.30.3
Compulsive drug intake1.21.82.4-0.71.4-1.41.5-1.41.51.41.31.3
One hour access (shock baseline)0.10.32.51.6-0.40.4-0.40.3-0.10.10.10.1
Social response proportion0.10.10.3-0.50.2-0.20.4-0.30.50.10.10.1
Social responses0.30.30.6-0.8-0.40.4-0.50.4-0.6-0.7-0.7-0.7
Social time1.21.82.8-1.71.6-1.61.5-1.41.11.21.01.1
Soleus weight0.20.51.0-0.8-0.40.4-0.60.5-0.8-1.0-0.9-0.9
Bone: stiffness0.91.62.8-1.7-0.70.8-1.01.0-1.5-1.4-1.4-1.5
Tibialis anterior weight0.20.50.9-0.0-0.70.7-0.90.7-1.0-0.7-0.7-0.7
Time to tail flick, vehicle, before self-admin0.30.31.61.3-0.20.10.1-0.10.50.70.50.5
Time to tail flick, vehicle, after self-admin0.40.91.20.5-1.01.0-1.11.1-1.1-0.8-0.9-0.9
Time to tail flick, test, before self-admin3.13.64.81.3-2.22.2-1.92.1-1.6-2.0-1.8-1.8
Time to tail flick, test, after self-admin3.84.04.80.5-2.22.2-2.22.1-2.1-2.1-2.0-2.0
Delta time to tail flick, vehicle, before/after SA0.30.40.6-0.6-0.30.3-0.50.5-0.8-0.7-0.7-0.7
Delta time to tail flick, test, before/after SA0.50.60.8-0.80.9-0.80.7-0.90.60.90.80.8
Tibia length0.30.70.90.9-1.01.0-0.91.0-0.8-0.7-0.7-0.7
Ambulatory time before self-admin0.51.42.3-0.41.2-1.21.1-1.21.01.51.41.4
Ambulatory time after self-admin0.71.12.10.70.8-0.80.9-0.81.11.41.41.4
Bone: tissue strength3.43.64.5-0.11.9-1.92.0-1.92.02.12.12.1
Total heroin consumption0.10.20.60.80.1-0.20.2-0.30.40.30.40.4
Bone: trabecular number1.12.02.7-1.11.7-1.61.5-1.51.31.31.31.3
Bone: trabecular spacing0.30.41.51.20.3-0.30.5-0.50.80.50.50.5
Bone: trabecular thickness1.11.62.4-1.0-1.01.0-1.21.2-1.5-1.3-1.4-1.4
Bone: trabecular tissue density1.52.64.6-2.1-1.01.1-1.41.3-1.9-1.8-1.8-1.8
Water consumed over 24 hours0.10.10.3-0.60.4-0.40.4-0.40.40.20.30.2
Number of responses in last shaping day0.70.92.4-1.5-0.50.6-0.70.8-1.2-0.9-1.0-0.9