Hub : Genes

Stim1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr1_166220291_166224149 0.04 0.03 3.0e-04 0.03 0.02 0.03 0.02 5.3e-04 9.8e-04 7.5e-04 9.7e-04
2 Adipose intron excision ratio chr1_166220291_166222124 0.03 0.02 8.2e-03 0.01 0.01 0.01 0 1.3e-02 5.1e-02 1.1e-02 9.2e-02
3 Liver gene expression Stim1 0.62 0.13 0.0e+00 0.28 0.43 0.44 0.44 8.9e-32 1.3e-52 1.9e-53 3.4e-53
4 NAcc gene expression Stim1 0.03 0.02 6.8e-04 0.02 0.02 0.01 0.02 4.0e-04 2.8e-04 5.6e-03 3.6e-04
5 NAcc intron excision ratio chr1_166220291_166224149 0.02 0.02 2.5e-03 0.01 0.01 0.01 0.01 3.1e-03 1.5e-02 2.5e-03 6.0e-03
6 Brain gene expression Stim1 0.06 0.04 3.4e-06 0.06 0.06 0.07 0.06 2.3e-06 2.1e-06 3.1e-07 6.1e-06
7 PL gene expression Stim1 0.04 0.03 1.2e-04 0.04 0.04 0.03 0.04 2.1e-05 6.4e-05 1.2e-04 4.3e-05
8 Brain intron excision ratio chr1_166220291_166224149 0.03 0.02 2.0e-03 0.01 0.01 0.01 0.01 2.8e-02 4.0e-02 1.9e-02 2.4e-02
9 Brain intron excision ratio chr1_166222216_166224149 0.04 0.03 7.0e-04 0.01 0.02 0.01 0.01 4.6e-02 4.2e-03 2.3e-02 2.7e-02
10 Brain mRNA stability Stim1 0.07 0.04 7.3e-08 0.07 0.08 0.07 0.08 2.8e-07 1.1e-07 1.6e-07 1.3e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.20.40.6-0.6-0.5-0.6-0.5-0.4-0.4-0.30.4-0.2
Area under the delay curve0.40.41.20.6-0.6-1.1-0.50.80.50.40.4-0.40.7
BMI with tail0.82.86.40.4-0.11.1-1.1-1.0-2.1-2.3-2.11.9-2.5
BMI without tail0.61.95.1-1.51.52.30.8-1.1-1.3-0.9-1.21.0-1.6
Body weight0.20.82.5-1.11.61.41.00.80.20.50.5-0.60.0
Weight adjusted by age0.50.82.2-1.11.51.21.20.40.90.30.5-0.50.2
Bone surface0.40.71.4-1.00.90.61.2-0.10.81.00.9-0.70.8
Bone volume0.20.40.6-0.60.60.30.80.10.70.70.7-0.60.7
Breakpoint value in progressive ratio session0.70.81.90.9-1.2-1.1-1.4-0.2-0.2-0.9-0.90.8-0.7
Number of licking bursts1.42.35.42.3-2.1-2.1-2.21.3-0.8-0.9-0.50.3-0.2
Context. condit. distance diff. score1.82.25.9-2.32.12.41.9-1.60.20.0-0.30.4-0.6
Locomotion velocity, session 12.02.23.90.8-0.9-0.1-1.3-1.3-1.8-1.9-2.01.8-1.7
Locomotion distance, session 11.01.22.5-0.70.41.20.2-1.6-1.0-1.1-1.31.3-1.4
Locomotion velocity, session 21.01.22.2-0.2-0.10.6-0.4-1.3-1.2-1.3-1.51.4-1.5
Locomotion distance, session 20.91.32.7-0.40.21.0-0.2-1.4-0.9-1.3-1.51.4-1.6
Locomotion velocity, session 30.30.31.0-1.00.70.80.8-0.80.20.1-0.10.1-0.1
Locomotion distance, session 30.50.61.9-1.00.81.00.8-1.4-0.0-0.3-0.50.5-0.4
Stereotopy head waving bouts, day 30.50.61.30.2-0.0-0.50.21.20.61.01.0-1.01.0
Stereotopy head waving duration, day 30.10.20.5-0.40.60.70.5-0.4-0.00.20.10.1-0.2
Locomotion velocity, session 71.01.12.20.3-0.40.2-0.7-1.0-1.4-1.3-1.51.2-1.3
Locomotion distance, session 70.10.10.30.5-0.5-0.5-0.60.3-0.2-0.4-0.40.1-0.1
Stereotopy head waving bouts, day 71.92.24.7-2.22.02.12.1-1.80.40.70.30.1-0.1
Stereotopy head waving duration, day 71.82.15.1-2.12.02.22.0-1.70.20.50.10.2-0.3
Locomotion velocity, session 80.80.92.5-1.61.31.41.3-0.90.50.10.00.0-0.1
Locomotion distance, session 81.62.46.4-2.21.92.51.5-1.8-0.2-0.5-0.80.8-1.2
Degree of sensitization distance0.80.83.20.4-0.2-0.8-0.21.80.80.80.8-1.11.0
Degree of sensitization stereotypy3.43.78.7-2.92.72.82.7-2.10.60.80.30.0-0.1
Conditioned locomotion0.50.51.50.4-0.5-0.9-0.31.20.70.50.6-0.80.8
Cocaine response after cond. corrected0.70.81.91.4-1.3-1.3-1.30.8-0.7-0.5-0.20.1-0.0
Cocaine response after cond. not corrected0.70.81.81.0-1.0-0.7-1.1-0.1-1.3-1.0-0.80.7-0.7
Cocaine response before conditioning1.41.64.3-1.10.91.70.7-2.1-1.0-0.9-1.21.3-1.3
Saline control response2.33.05.2-1.92.01.22.30.51.62.01.7-1.71.6
Bone: connectivity density1.01.53.00.5-0.70.1-0.8-1.7-1.4-1.5-1.51.6-1.4
Bone: cortical apparent density0.81.12.71.5-1.4-1.6-1.31.3-0.10.10.1-0.30.4
Bone: cortical area0.10.20.4-0.40.50.30.40.30.60.30.2-0.40.3
Bone: cortical porosity0.10.10.3-0.1-0.1-0.30.20.00.40.50.4-0.40.5
Bone: cortical porosity0.20.20.3-0.30.2-0.00.4-0.20.60.60.5-0.40.6
Bone: cortical thickness0.71.11.81.0-0.9-0.4-1.2-0.5-1.1-1.3-1.31.1-1.1
Bone: cortical thickness0.00.00.1-0.20.30.30.10.30.20.20.0-0.10.0
Bone: cortical tissue density0.81.12.71.6-1.4-1.6-1.31.3-0.20.10.1-0.30.4
Condit. Reinf. active minus inactive responses1.71.93.1-0.91.20.31.41.31.21.81.7-1.71.6
Condit. Reinf. active-inactive response ratio3.13.35.3-1.21.40.31.81.61.92.32.3-2.22.2
Condit. Reinf. active responses0.91.12.1-0.20.3-0.40.61.30.81.41.4-1.41.4
Condit. Reinf. inactive responses0.30.40.80.8-0.9-0.8-0.80.1-0.6-0.5-0.30.3-0.3
Incentive salience index mean1.11.32.3-0.50.7-0.01.01.11.11.51.5-1.41.4
Condit. Reinf. lever presses0.00.00.10.10.10.10.1-0.10.10.20.2-0.00.1
Condit. Reinf. active minus inactive responses5.16.613.7-3.73.53.03.7-0.52.22.31.8-1.61.3
Condit. Reinf. active-inactive response ratio0.80.92.3-1.51.31.31.4-0.90.40.50.3-0.10.1
Condit. Reinf. active responses6.99.618.8-4.34.23.34.30.02.82.92.4-2.21.8
Condit. Reinf. inactive responses4.15.38.9-2.83.02.03.00.92.32.42.1-2.11.7
Condit. Reinf. lever presses8.311.426.9-5.25.04.74.9-1.42.22.31.6-1.30.7
Condit. Reinf. lever reinforcers received7.210.120.1-4.44.43.54.5-0.22.82.92.4-2.21.7
Conditioned reinforcement - actives0.10.10.3-0.4-0.20.10.0-0.30.0-0.2-0.50.4-0.3
Conditioned reinforcement - inactives0.60.92.01.1-1.0-1.4-0.61.10.80.40.9-0.81.0
Conditioned locomotion0.91.24.6-0.80.51.00.3-2.2-0.4-0.9-1.11.2-1.2
Patch foraging indifference point 0 sec1.01.95.5-1.82.22.41.8-1.1-0.20.80.3-0.1-0.2
Patch foraging indifference point AUC0.40.50.8-0.80.80.60.80.40.80.90.7-0.70.5
Delay disc. indifference point, 0s delay0.60.71.9-1.11.41.01.1-0.10.90.50.4-0.40.3
Delay disc. indifference point, 16s delay1.01.11.80.6-0.7-1.3-0.31.31.31.01.2-1.11.3
Delay disc. indifference point, 2s delay0.60.71.4-0.80.70.20.90.50.71.20.9-0.91.0
Delay disc. indifference point, 24s delay1.11.23.51.4-1.5-1.9-1.21.40.10.20.5-0.60.8
Delay disc. indifference point, 4s delay1.41.53.6-1.11.30.51.20.81.91.41.2-1.21.1
Delay disc. indifference point, 8s delay0.20.30.90.6-0.7-1.0-0.70.3-0.00.1-0.10.00.2
Indifference point function ln k0.10.20.8-0.30.30.50.2-0.9-0.6-0.4-0.40.5-0.4
Indifference point function log k0.10.20.8-0.30.30.50.2-0.9-0.6-0.4-0.40.5-0.4
Patch foraging total patch changes 0 sec0.91.85.4-1.72.12.31.7-1.1-0.40.60.10.1-0.4
Patch foraging total patch changes 12 sec0.81.01.9-1.31.41.21.30.20.51.20.9-0.80.5
Patch foraging total patch changes 18 sec0.60.92.2-1.41.41.51.3-0.3-0.01.00.5-0.40.2
Patch foraging total patch changes 24 sec0.81.43.2-1.41.81.51.50.40.71.11.0-0.90.6
Patch foraging total patch changes 6 sec0.60.92.9-1.11.71.71.3-0.50.00.50.4-0.2-0.1
Patch foraging time to switch 0 sec1.42.97.42.5-2.7-2.7-2.50.8-0.6-1.0-0.50.5-0.1
Patch foraging water rate 0 sec1.12.36.0-2.22.42.42.2-0.60.21.00.4-0.50.2
Patch foraging water rate 12 sec1.42.96.3-1.41.52.50.8-2.1-1.6-1.3-1.71.6-2.0
Patch foraging water rate 18 sec1.32.05.8-2.12.12.41.7-1.3-0.0-0.0-0.40.3-0.7
Patch foraging water rate 24 sec0.60.91.7-0.40.41.00.0-1.3-0.6-1.0-1.21.1-1.3
Patch foraging water rate 6 sec0.91.32.3-0.80.81.50.4-1.5-1.0-0.9-1.31.2-1.3
Seeking ratio, delayed vs. immediate footshock1.72.14.41.9-2.1-1.5-1.8-0.5-1.4-1.4-1.11.0-0.7
Distance traveled before self-admin0.70.92.10.6-0.6-0.1-0.9-1.1-0.8-1.5-1.01.1-1.1
Distance traveled after self-admin1.72.14.80.5-0.40.5-0.8-2.2-1.1-1.9-1.71.9-1.8
Extensor digitorum longus weight0.10.20.60.5-0.6-0.5-0.70.70.3-0.5-0.40.2-0.3
Bone: elastic displacement2.02.34.71.7-1.6-0.9-1.8-0.7-2.2-1.7-1.51.4-1.3
Bone: elastic work3.64.78.82.1-2.0-0.9-2.4-1.2-3.0-2.5-2.52.3-2.1
Bone: endosteal estimation1.43.04.9-1.91.70.82.01.02.21.91.8-1.81.7
Bone: endosteal perimeter1.43.15.3-2.12.11.42.30.51.71.81.7-1.61.5
Epididymis fat weight0.20.71.41.0-0.9-0.7-1.20.4-1.0-0.8-0.70.5-0.6
Delta time in closed arm before/after self-admin0.70.61.81.1-1.0-1.3-0.90.80.4-0.10.5-0.50.5
Delta time in open arm before/after self-admin2.52.54.6-1.91.91.62.20.61.91.31.6-1.21.1
Diff in mean of infusions in LGA sessions2.12.66.11.7-1.4-2.5-1.01.91.40.81.6-1.51.8
Delay discount exponential model param0.30.41.2-0.70.71.10.6-0.6-0.3-0.3-0.20.2-0.5
Extinction: sum of active levers before priming0.10.10.4-0.30.0-0.20.2-0.10.00.70.4-0.30.4
Active lever presses in extinction session 61.21.24.6-0.60.81.40.5-2.1-1.0-0.9-0.71.0-1.1
Bone: final force0.71.12.00.6-0.7-1.3-0.31.41.30.91.0-1.11.3
Bone: final moment0.50.81.60.4-0.4-1.0-0.11.21.30.80.9-1.01.2
Food consumed during 24 hour testing period1.21.74.3-1.81.82.11.7-1.50.10.2-0.20.4-0.5
Glucose0.30.51.0-0.0-0.30.3-0.4-0.9-0.8-0.7-1.01.0-1.0
Heart weight0.91.53.7-1.31.91.41.60.10.91.01.2-0.90.7
Delay discount hyperbolic model param0.30.31.0-0.50.51.00.5-0.7-0.5-0.4-0.40.4-0.6
Intermittent access intake day 1-15 change1.22.44.9-0.30.61.5-0.0-2.2-1.8-1.8-1.71.7-1.9
Intermittent access intake escalation1.02.14.5-0.60.91.70.3-2.1-1.5-1.6-1.51.5-1.7
Intermittent access intake escalation 20.50.51.1-0.30.50.80.0-1.0-0.7-0.8-0.80.8-0.9
Intermitt. access day 1 inactive lever presses0.41.44.02.0-1.2-1.9-1.41.3-0.3-0.00.5-0.70.8
Intermitt. access day 15 inactive lever presses0.10.20.60.7-0.1-0.5-0.30.6-0.2-0.30.2-0.20.3
Intermitt. access escalation Index0.10.10.3-0.20.0-0.20.20.50.30.40.4-0.50.4
Intermittent access day 1 total infusions0.50.81.7-1.31.10.61.10.21.20.90.4-0.50.6
Intermittent access day 15 total infusions0.30.51.1-1.11.01.10.9-0.70.1-0.1-0.40.3-0.3
Intermittent access terminal intake (last 3 days)0.40.51.6-1.31.11.01.0-0.70.20.2-0.20.0-0.0
Intermittent access total infusions0.40.51.7-1.30.90.90.9-0.90.40.3-0.20.1-0.1
Intermittent access day 1 locomotion0.20.30.7-0.20.1-0.30.40.40.50.70.7-0.60.8
Intermittent access day 15 total locomotion0.40.71.6-0.1-0.40.4-0.1-1.1-1.3-0.9-1.11.1-0.9
Intermittent access total locomotion0.20.20.6-0.70.50.50.7-0.8-0.20.1-0.10.10.0
Intermittent access standard deviation0.10.30.80.10.40.6-0.2-0.4-0.1-0.9-0.50.5-0.8
Left kidney weight0.10.61.7-0.81.31.20.80.50.80.10.5-0.4-0.2
Right kidney weight0.41.83.6-1.11.91.31.41.31.90.91.3-1.30.7
Cocaine induced anxiety1.41.95.42.2-1.9-2.3-1.61.0-0.8-0.00.5-0.60.9
Post-drug Anxiety1.61.73.61.2-1.5-1.9-0.51.2-0.21.11.3-1.41.7
Baseline Anxiety1.92.24.1-1.81.41.22.00.51.61.71.4-1.31.2
Tail length2.610.014.2-3.13.21.63.62.03.53.83.5-3.53.1
Length with tail2.08.812.4-2.73.01.43.22.23.43.53.3-3.32.9
Length without tail0.20.62.0-0.20.60.10.50.81.40.60.9-0.80.7
Times rat made contact with spout0.20.20.60.4-0.4-0.7-0.20.70.40.30.4-0.50.5
Lifetime Intake0.60.82.4-1.61.11.21.1-1.00.40.3-0.30.1-0.1
Liver weight, left0.40.71.70.4-0.5-1.0-0.31.31.10.60.9-0.90.9
Liver weight, right0.71.34.40.3-0.3-1.0-0.12.10.91.01.2-1.51.3
Locomotor activity0.30.41.5-0.91.11.20.8-0.3-0.1-0.1-0.20.2-0.4
Locomotor testing distance0.71.33.3-1.81.81.81.6-0.50.60.50.2-0.2-0.1
Locomotor testing rearing0.40.81.7-1.31.20.91.20.11.00.90.6-0.70.5
Locomotion in novel chamber1.01.22.01.1-0.8-0.3-1.1-1.0-1.3-1.4-1.21.2-1.2
Locomotion in novel chamber post-restriction0.30.40.9-1.00.50.90.6-0.90.1-0.2-0.40.7-0.6
Fecal boli incidents, locomotor time 10.81.13.01.5-1.6-1.7-1.40.5-0.8-0.4-0.40.20.2
Change in fecal boli incidents, locomotor task0.20.20.8-0.70.40.40.5-0.20.90.50.5-0.10.0
Time >=10cm from walls, locomotor time 10.50.61.2-0.90.60.61.1-0.20.51.00.8-0.60.6
Bouts of movement, locomotor time 10.80.91.9-0.10.2-0.00.81.01.20.81.4-1.31.3
Total resting periods, locomotor time 10.20.20.60.3-0.4-0.30.20.60.10.30.7-0.60.8
Rest time, locomotor task time 10.10.10.4-0.0-0.6-0.40.10.0-0.30.40.2-0.30.5
Distance moved, locomotor task time 10.10.10.20.00.30.1-0.2-0.10.4-0.4-0.30.3-0.4
Vertical activity count, locomotor time 10.10.11.00.10.2-0.2-0.10.51.00.10.3-0.20.2
Time >=10cm from walls, locomotor time 22.63.86.4-2.11.91.12.30.62.52.42.1-1.91.8
Bouts of movement, locomotor time 21.72.85.9-0.70.5-0.70.91.92.41.92.0-2.12.2
Total resting periods, locomotor time 21.11.93.5-0.2-0.2-1.10.31.81.91.51.6-1.71.8
Rest time, locomotor task time 21.51.94.41.7-2.1-1.6-1.90.3-1.5-1.1-1.00.8-0.6
Distance moved, locomotor task time 21.31.53.2-1.81.71.61.8-0.51.11.00.7-0.60.4
Vertical activity count, locomotor time 20.70.93.1-0.70.7-0.00.70.61.81.31.1-1.01.0
Light reinforcement 11.33.15.22.0-1.9-1.2-2.3-0.4-2.2-2.0-1.81.6-1.6
Light reinforcement 22.94.47.90.5-0.60.7-1.2-2.4-2.4-2.6-2.82.7-2.8
Bone: marrow area1.22.74.5-1.71.50.71.81.12.11.81.8-1.71.6
Bone: maximum diameter1.32.44.6-2.12.11.62.10.21.41.51.2-1.21.0
Bone: maximum force0.20.30.70.4-0.5-0.8-0.30.70.80.30.4-0.50.7
Bone: maximum moment0.10.20.60.1-0.3-0.5-0.10.50.70.20.2-0.40.5
Mean time between licks in bursts3.38.111.4-2.83.01.73.41.83.23.33.1-3.02.7
Mean num. licks in bursts1.32.04.6-2.11.91.92.1-1.10.91.00.7-0.50.4
Cd content in liver0.30.40.90.2-0.4-0.8-0.00.90.20.70.6-0.70.9
Co content in liver2.12.44.1-1.61.40.61.81.01.62.01.7-1.81.7
Cu content in liver1.51.83.2-1.01.00.31.21.11.81.61.6-1.51.5
Fe content in liver0.00.10.10.2-0.2-0.3-0.10.20.30.20.2-0.20.3
K content in liver0.30.20.80.7-0.5-0.7-0.50.90.00.00.2-0.30.2
Mg content in liver0.10.10.30.00.10.4-0.1-0.3-0.4-0.4-0.40.4-0.6
Mn content in liver2.02.33.31.6-1.6-0.9-1.8-0.9-1.5-1.8-1.61.6-1.4
Na content in liver0.50.51.7-0.80.81.10.7-1.30.0-0.3-0.30.5-0.5
Rb content in liver0.30.30.8-0.30.1-0.20.60.20.40.90.7-0.70.9
Se content in liver3.23.88.32.9-2.9-2.6-2.80.1-1.2-1.6-1.11.1-0.6
Sr content in liver1.71.43.1-0.40.51.30.0-1.8-1.1-1.3-1.41.5-1.6
Zn content in liver1.21.43.4-1.81.81.81.6-0.60.70.50.3-0.2-0.1
Bone: minimum diameter1.22.24.6-1.11.20.41.41.32.11.61.6-1.71.6
Time in familiar zone, hab. session 10.10.10.3-0.60.40.50.3-0.2-0.20.0-0.20.1-0.2
Time in novel zone, hab. session 10.40.40.70.6-0.3-0.7-0.20.80.50.40.7-0.70.7
Total zone transitions, hab. session 10.40.51.4-0.40.20.60.1-1.2-0.6-0.8-0.80.8-0.8
Total locomotion distance, hab. session 10.81.13.50.10.1-0.60.21.90.91.21.2-1.41.2
Locomotion velocity, hab. session 10.50.72.70.1-0.1-0.6-0.01.60.60.80.9-1.00.9
Time in familiar zone, hab. session 22.42.54.4-2.02.01.52.10.71.41.71.4-1.41.2
Time in novel zone, hab. session 22.52.64.21.4-1.4-0.6-1.7-1.2-1.7-2.1-1.81.8-1.7
Total zone transitions, hab. session 21.31.74.8-1.81.92.21.6-1.50.0-0.1-0.20.4-0.7
Total locomotion distance, hab. session 21.11.42.3-1.01.20.61.11.51.21.31.3-1.41.0
Locomotion velocity, hab. session 21.11.52.7-0.91.10.41.01.71.31.41.4-1.51.1
Novel to familiar place preference ratio2.42.65.1-0.20.5-0.51.01.91.72.02.3-2.12.1
Novelty place preference2.22.34.4-0.30.6-0.41.01.81.61.82.1-2.02.0
Time in novel zone, NPP test2.52.64.9-0.50.8-0.31.21.81.72.02.2-2.12.1
Total zone transitions, NPP test1.21.73.0-0.0-0.10.8-0.4-1.6-1.5-1.6-1.61.7-1.7
Total locomotion distance, NPP test0.20.30.60.5-0.4-0.2-0.70.8-0.7-0.5-0.50.3-0.6
Locomotion velocity, NPP test0.40.61.10.8-0.7-0.4-1.10.7-1.0-0.8-0.70.5-0.8
Intraocular pressure0.30.41.40.3-0.30.1-0.2-1.2-0.6-0.7-0.60.9-0.7
Delta distance traveled before/after self-admin0.60.61.6-1.21.00.91.2-0.50.60.70.3-0.30.3
Delta ambulatory time before/after self-admin0.40.51.2-1.10.80.91.1-0.50.60.60.1-0.10.1
Parametrial fat weight1.53.56.51.1-1.2-0.1-1.7-1.6-2.0-2.3-2.52.4-2.4
Pavlov. Cond. lever latency0.60.71.31.0-0.8-0.5-1.10.1-0.9-1.1-0.90.8-0.9
Pavlov. Cond. magazine entry latency1.82.35.5-2.32.22.12.2-0.81.11.10.6-0.50.3
Pavlov. Cond. change in total contacts1.51.62.6-1.31.10.51.60.21.51.61.4-1.31.4
Pavlov. Cond. index score1.21.53.6-1.91.51.41.8-0.61.11.20.7-0.70.6
Pavlov. Cond. latency score1.21.53.1-1.71.41.21.8-0.41.21.30.9-0.80.8
Pavlov. Cond. lever contacts0.50.61.3-1.10.90.71.1-0.30.80.90.6-0.50.5
Pavlov. Cond. magazine entry number1.72.24.82.2-2.0-1.8-2.20.7-1.2-1.3-0.90.7-0.6
Pavlov. Cond. intertrial magazine entries0.40.51.41.1-1.1-1.2-0.90.5-0.2-0.10.1-0.10.3
Pavlov. Cond. lever-magazine prob. diff.1.11.33.0-1.71.41.21.7-0.61.01.10.7-0.60.6
Pavlov. Cond. response bias0.80.92.3-1.51.31.31.4-0.60.70.70.4-0.30.2
Pavlov. Cond. lever latency9.012.330.35.5-5.3-5.4-5.02.1-1.6-1.6-0.80.60.1
Pavlov. Cond. magazine entry latency3.23.810.1-2.22.23.21.5-2.4-1.0-1.0-1.61.5-2.0
Pavlov. Cond. change in total contacts6.710.726.0-5.14.95.14.6-2.21.31.50.7-0.5-0.2
Pavlov. Cond. index score6.48.622.9-4.64.44.83.9-2.20.80.80.10.0-0.7
Pavlov. Cond. latency score5.67.520.6-4.24.14.53.6-2.30.40.5-0.20.3-0.9
Pavlov. Cond. lever contacts8.511.728.0-5.35.25.24.9-1.81.61.81.1-0.80.1
Pavlov. Cond. magazine entry number4.25.215.13.1-3.1-3.9-2.52.60.20.30.9-1.01.5
Pavlov. Cond. intertrial magazine entries1.62.44.2-0.60.7-0.31.11.61.82.02.1-2.02.0
Pavlov. Cond. lever-magazine prob. diff.6.28.322.0-4.54.44.73.9-2.10.90.90.2-0.1-0.6
Pavlov. Cond. response bias8.711.830.3-5.35.35.54.8-2.41.21.30.5-0.3-0.5
Time in closed arm before self-admin1.01.34.5-1.81.52.11.6-0.7-0.20.5-0.20.2-0.5
Time in closed arm after self-admin0.30.30.80.9-0.9-0.8-0.70.3-0.1-0.2-0.00.00.1
Time in open arm before self-admin3.64.08.12.9-2.3-2.3-2.80.1-2.3-1.8-1.41.2-1.0
Time in open arm after self-admin0.20.20.4-0.30.60.20.50.60.20.40.6-0.50.5
Bone: periosteal estimation0.61.32.2-1.41.20.71.30.61.51.11.0-1.11.0
Bone: periosteal perimeter0.71.22.4-1.51.61.21.50.21.10.80.8-0.80.6
Bone: post-yield work0.10.10.3-0.50.40.30.3-0.00.50.20.0-0.10.0
Progressive ratio test 1 active lever presses0.00.00.2-0.1-0.2-0.20.1-0.50.20.0-0.10.10.1
Progressive ratio test 1 breakpoint0.00.10.3-0.1-0.2-0.20.0-0.60.20.1-0.10.10.1
Progressive ratio test 1 inactive lever presses0.20.30.90.8-0.9-0.9-0.70.1-0.4-0.2-0.10.10.1
Progressive ratio test 2 active lever presses0.10.10.3-0.40.0-0.00.3-0.30.60.30.0-0.10.2
Progressive ratio test 2 breakpoint0.10.10.4-0.50.10.00.4-0.30.60.30.0-0.00.2
Progressive ratio test 2 inactive lever presses0.10.10.2-0.0-0.3-0.0-0.2-0.40.1-0.4-0.50.5-0.4
Incentive Sensitization - Responses0.10.20.7-0.60.40.20.4-0.10.80.40.1-0.10.2
Incentive Sensitization - Breakpoint0.10.10.4-0.50.30.20.3-0.30.60.1-0.20.2-0.1
Sum of active levers in priming session hrs 5-60.30.31.2-0.30.40.60.1-1.1-0.3-0.2-0.40.4-0.5
Progressive ratio0.81.32.4-0.50.51.40.3-1.4-1.5-1.2-1.11.3-1.4
Food seeking constrained by brief footshock1.31.63.2-1.81.51.51.80.61.01.11.1-1.00.6
Seeking ratio, punishment vs. effort1.11.63.5-1.00.80.01.01.21.91.71.3-1.51.3
Retroperitoneal fat weight0.52.04.51.9-2.0-1.9-2.11.6-0.9-0.7-0.70.2-0.4
Reaction time number correct0.10.30.60.1-0.20.2-0.3-0.7-0.7-0.4-0.80.7-0.7
Reaction time mean minus median0.20.50.8-0.80.90.50.90.60.80.60.7-0.90.7
Reaction time mean minus median AUC0.10.30.6-0.70.70.50.80.10.60.40.4-0.50.4
Reaction time num false alarms1.52.15.71.9-2.0-2.4-1.51.9-0.50.30.5-0.70.9
Reaction time num false alarms AUC1.21.85.01.8-2.0-2.2-1.61.5-0.7-0.00.2-0.30.6
Reaction time trials correct on left0.10.30.60.1-0.20.2-0.3-0.7-0.7-0.4-0.80.7-0.7
Reaction time trials on left0.20.30.70.1-0.30.2-0.3-0.7-0.8-0.5-0.90.7-0.7
Reaction time mean1.22.04.81.3-1.5-2.2-1.12.21.10.60.9-1.11.3
Reaction time mean AUC1.32.15.41.5-1.7-2.3-1.22.11.00.50.8-1.01.2
Median of all reaction times1.82.57.01.8-2.1-2.7-1.62.20.90.30.6-0.91.1
Reaction time omissions0.20.30.70.7-0.8-0.8-0.70.6-0.0-0.2-0.20.0-0.0
Reaction time false alarm rate1.21.74.61.8-1.9-2.2-1.51.6-0.5-0.00.3-0.40.6
Reaction time premature initiation rate1.52.13.8-1.71.81.21.70.71.91.41.3-1.41.0
Reaction time premature initiations0.50.91.8-1.31.31.11.20.21.20.80.5-0.60.3
Std. dev. reaction times0.91.73.3-0.1-0.0-0.90.41.81.71.41.5-1.71.7
Reaction time trials completed0.20.30.70.1-0.30.2-0.3-0.7-0.8-0.5-0.90.7-0.7
Reaction time trials AUC0.10.20.40.1-0.20.2-0.2-0.4-0.6-0.3-0.60.5-0.5
Run reversals in cocaine runway, females0.50.51.2-0.71.10.60.80.30.30.60.6-0.80.4
Run reversals in cocaine runway, males0.30.30.80.8-0.9-0.8-0.70.10.0-0.40.10.20.0
Latency to leave start box in cocaine runway0.70.82.81.3-1.3-1.7-1.40.10.00.1-0.0-0.10.3
Latency to leave start box in cocaine runway, F1.01.13.01.0-0.9-1.7-0.91.10.51.00.9-1.11.2
Latency to leave start box in cocaine runway, M1.11.11.70.8-1.0-0.5-1.2-1.1-0.6-1.1-1.21.3-1.1
Std. dev. time between licks in bursts2.33.24.6-1.31.40.51.61.92.12.12.1-2.11.9
Total sessions with >9 infusions0.81.03.9-2.01.31.31.3-0.60.30.6-0.30.0-0.1
Short access day 1 total inactive lever presses0.40.51.70.30.1-0.50.01.30.50.70.7-0.80.9
Short access day 10 total inactive lever presses0.51.23.01.7-1.3-1.6-1.31.4-0.9-0.10.3-0.30.5
Short access day 1 total infusions1.72.25.1-2.31.91.31.90.81.71.50.8-1.00.8
Short access day 10 total infusions0.60.82.7-1.61.31.21.1-0.80.20.4-0.40.1-0.2
Short access total infusions1.01.33.8-2.01.71.41.6-0.51.00.80.1-0.30.2
Short access day 1 locomotion0.40.51.3-0.91.21.00.7-0.80.4-0.2-0.50.4-0.4
Short access day 10 total locomotion0.20.40.8-0.70.90.90.5-0.70.1-0.2-0.50.5-0.6
Short access total locomotion0.30.41.7-0.30.10.30.1-1.3-0.3-0.5-0.80.7-0.6
One hour access (0.3 mA shock)0.40.41.4-0.70.30.80.3-1.20.1-0.3-0.50.6-0.7
Compulsive drug intake1.01.12.21.5-1.1-0.4-1.20.5-1.1-1.4-0.81.1-1.0
One hour access (shock baseline)0.81.34.7-1.51.21.41.0-2.20.70.0-0.50.4-0.6
Social response proportion0.20.31.20.9-0.2-0.4-0.51.1-0.1-0.10.3-0.30.1
Social responses0.60.83.10.5-0.2-0.7-0.21.80.80.81.0-1.00.9
Social time1.41.94.41.8-2.1-1.8-2.00.3-0.9-1.0-1.00.9-0.6
Soleus weight0.31.03.60.5-0.5-1.0-0.31.90.90.91.0-1.11.0
Bone: stiffness1.32.14.60.8-0.8-1.7-0.32.11.61.41.5-1.61.8
Tibialis anterior weight0.10.51.1-0.40.3-0.10.41.00.80.70.7-0.90.8
Time to tail flick, vehicle, before self-admin0.70.82.3-0.71.11.50.8-0.3-1.3-0.3-0.70.5-0.7
Time to tail flick, vehicle, after self-admin0.40.61.3-1.10.70.51.10.2-0.00.90.7-0.60.7
Time to tail flick, test, before self-admin2.82.95.4-1.82.21.52.30.81.31.71.8-1.61.4
Time to tail flick, test, after self-admin3.23.35.9-1.21.60.51.81.32.42.02.3-2.22.0
Delta time to tail flick, vehicle, before/after SA0.30.30.6-0.1-0.2-0.7-0.00.20.80.50.7-0.50.7
Delta time to tail flick, test, before/after SA0.50.51.31.1-1.0-1.0-1.10.2-0.1-0.7-0.40.3-0.3
Tibia length0.30.91.7-1.31.11.01.3-0.81.20.60.6-0.30.4
Ambulatory time before self-admin0.60.91.80.7-0.8-0.4-1.1-0.8-0.7-1.3-1.11.1-1.0
Ambulatory time after self-admin1.01.25.1-0.3-0.00.7-0.1-2.2-0.2-1.2-1.31.4-1.3
Bone: tissue strength2.62.64.50.9-1.1-0.1-1.3-1.6-1.8-2.1-2.12.0-1.9
Total heroin consumption0.20.30.6-0.40.60.70.2-0.70.2-0.4-0.40.5-0.6
Bone: trabecular number1.11.82.51.4-1.6-1.0-1.6-0.9-1.5-1.4-1.41.4-1.1
Bone: trabecular spacing0.50.71.4-0.60.61.10.3-1.2-0.5-0.4-0.80.9-1.1
Bone: trabecular thickness1.21.42.80.2-0.1-0.90.21.51.51.31.4-1.51.7
Bone: trabecular tissue density2.84.19.61.1-0.9-2.2-0.43.12.01.82.2-2.42.5
Water consumed over 24 hours0.10.20.40.6-0.5-0.5-0.50.3-0.3-0.3-0.10.1-0.1
Number of responses in last shaping day1.41.52.80.8-0.9-1.7-0.41.41.31.21.4-1.41.6