Stim1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr1_166220291_166224149 0.04 0.03 3.0e-04 0.03 0.02 0.03 0.02 5.3e-04 9.8e-04 7.5e-04 9.3e-04
2 Adipose intron excision ratio chr1_166220291_166222124 0.03 0.02 8.2e-03 0.01 0.01 0.01 0 1.3e-02 5.1e-02 1.1e-02 1.0e-01
3 Liver gene expression Stim1 0.62 0.13 0.0e+00 0.28 0.43 0.44 0.44 8.9e-32 1.3e-52 1.6e-53 3.7e-53
4 NAcc gene expression Stim1 0.03 0.02 6.8e-04 0.02 0.02 0.01 0.02 4.0e-04 2.8e-04 5.2e-03 3.5e-04
5 NAcc intron excision ratio chr1_166220291_166224149 0.02 0.02 2.5e-03 0.01 0.01 0.01 0.01 3.1e-03 1.5e-02 2.5e-03 6.1e-03
6 Brain gene expression Stim1 0.06 0.04 3.4e-06 0.06 0.06 0.07 0.06 2.3e-06 2.1e-06 3.1e-07 5.9e-06
7 PL gene expression Stim1 0.04 0.03 1.2e-04 0.04 0.04 0.03 0.04 2.1e-05 6.4e-05 1.2e-04 4.3e-05
8 Brain intron excision ratio chr1_166220291_166224149 0.03 0.02 2.0e-03 0.01 0.01 0.01 0.01 2.8e-02 4.0e-02 2.0e-02 2.5e-02
9 Brain intron excision ratio chr1_166222216_166224149 0.04 0.03 7.0e-04 0.01 0.02 0.01 0.01 4.6e-02 4.2e-03 2.3e-02 2.7e-02
10 Brain mRNA stability Stim1 0.07 0.04 7.3e-08 0.07 0.08 0.07 0.08 2.8e-07 1.1e-07 1.6e-07 1.2e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.20.4-0.60.60.5-0.60.50.40.40.30.4-0.2
Area under the delay curve0.30.41.2-0.60.61.1-0.5-0.8-0.6-0.4-0.4-0.40.7
BMI with tail0.82.86.4-0.40.1-1.1-1.11.02.22.32.11.9-2.5
BMI without tail0.41.95.11.5-1.5-2.20.81.11.40.91.21.0-1.6
Body weight0.20.82.51.1-1.6-1.41.0-0.8-0.1-0.5-0.5-0.60.0
Weight adjusted by age0.30.82.21.1-1.5-1.21.2-0.4-0.9-0.3-0.5-0.50.2
Bone surface0.40.71.41.0-0.9-0.61.20.1-0.8-1.0-0.9-0.70.8
Bone volume0.20.40.60.6-0.6-0.30.8-0.1-0.7-0.7-0.7-0.60.7
Breakpoint value in progressive ratio session0.40.81.9-0.91.21.1-1.40.20.20.90.90.8-0.7
Number of licking bursts0.82.35.4-2.32.12.1-2.2-1.30.80.90.50.3-0.2
Context. condit. distance diff. score1.82.25.92.3-2.1-2.41.91.6-0.3-0.00.30.4-0.6
Locomotion velocity, session 11.92.23.9-0.80.90.1-1.31.31.81.92.01.8-1.7
Locomotion distance, session 11.01.22.50.7-0.4-1.20.21.61.01.11.31.3-1.4
Locomotion velocity, session 21.01.22.20.20.1-0.6-0.41.31.21.31.51.4-1.5
Locomotion distance, session 20.91.32.70.4-0.2-1.0-0.21.40.91.31.51.4-1.6
Locomotion velocity, session 30.30.41.01.0-0.7-0.80.80.8-0.2-0.10.10.1-0.1
Locomotion distance, session 30.50.61.91.0-0.8-1.00.81.40.00.30.50.5-0.4
Stereotopy head waving bouts, day 30.50.61.3-0.20.00.50.2-1.2-0.5-1.0-1.0-1.01.0
Stereotopy head waving duration, day 30.10.20.50.4-0.6-0.70.50.40.0-0.2-0.10.1-0.2
Locomotion velocity, session 71.01.12.2-0.30.4-0.2-0.71.01.31.31.51.2-1.3
Locomotion distance, session 70.10.10.3-0.50.50.5-0.6-0.30.20.40.40.1-0.1
Stereotopy head waving bouts, day 71.92.24.72.2-2.0-2.12.11.8-0.4-0.7-0.30.1-0.1
Stereotopy head waving duration, day 71.72.15.12.1-2.0-2.22.01.7-0.2-0.5-0.10.2-0.3
Locomotion velocity, session 80.80.92.51.6-1.3-1.41.30.9-0.5-0.1-0.00.0-0.1
Locomotion distance, session 81.62.46.42.2-1.9-2.51.51.80.20.50.80.8-1.2
Degree of sensitization distance0.80.83.2-0.40.20.8-0.2-1.8-0.8-0.8-0.8-1.11.0
Degree of sensitization stereotypy3.33.78.72.9-2.7-2.82.72.1-0.6-0.8-0.30.0-0.1
Conditioned locomotion0.50.51.5-0.40.50.9-0.3-1.2-0.8-0.5-0.6-0.80.8
Cocaine response after cond. corrected0.60.81.9-1.41.31.3-1.3-0.80.70.50.20.1-0.0
Cocaine response after cond. not corrected0.60.81.9-1.01.00.7-1.10.11.41.00.80.7-0.7
Cocaine response before conditioning1.41.64.31.1-0.9-1.70.72.11.10.91.21.3-1.3
Saline control response2.23.05.21.9-2.0-1.22.3-0.5-1.5-2.0-1.7-1.71.6
Bone: connectivity density1.01.53.0-0.50.7-0.1-0.81.71.41.51.51.6-1.4
Bone: cortical apparent density0.71.12.7-1.51.41.6-1.3-1.30.1-0.1-0.1-0.30.4
Bone: cortical area0.10.20.40.4-0.5-0.40.4-0.3-0.7-0.3-0.2-0.40.3
Bone: cortical porosity0.10.10.30.10.10.30.2-0.0-0.4-0.5-0.4-0.40.5
Bone: cortical porosity0.20.20.30.3-0.20.00.40.2-0.6-0.6-0.5-0.40.6
Bone: cortical thickness0.71.11.8-1.00.90.4-1.20.51.11.31.31.1-1.1
Bone: cortical thickness0.00.00.10.2-0.3-0.30.1-0.3-0.1-0.2-0.0-0.10.0
Bone: cortical tissue density0.71.12.7-1.61.41.6-1.3-1.30.1-0.1-0.1-0.30.4
Condit. Reinf. active minus inactive responses1.61.83.10.9-1.2-0.31.4-1.3-1.2-1.8-1.7-1.71.6
Condit. Reinf. active-inactive response ratio3.03.35.31.2-1.4-0.31.8-1.6-1.8-2.3-2.3-2.22.2
Condit. Reinf. active responses0.91.12.10.2-0.30.40.6-1.3-0.7-1.4-1.4-1.41.4
Condit. Reinf. inactive responses0.30.40.8-0.80.90.8-0.8-0.10.60.50.30.3-0.3
Incentive salience index mean1.01.32.30.5-0.70.01.0-1.1-1.1-1.5-1.5-1.41.4
Condit. Reinf. lever presses0.00.00.1-0.1-0.1-0.10.10.1-0.0-0.2-0.2-0.00.1
Condit. Reinf. active minus inactive responses4.36.613.73.7-3.5-3.03.70.5-2.1-2.3-1.8-1.61.3
Condit. Reinf. active-inactive response ratio0.60.92.31.5-1.3-1.31.40.9-0.4-0.5-0.3-0.10.1
Condit. Reinf. active responses6.79.618.84.3-4.2-3.34.3-0.0-2.7-2.9-2.4-2.21.8
Condit. Reinf. inactive responses3.65.38.92.8-3.0-2.03.0-0.9-2.2-2.4-2.1-2.11.7
Condit. Reinf. lever presses7.811.426.95.2-5.0-4.74.91.4-2.1-2.3-1.6-1.30.7
Condit. Reinf. lever reinforcers received7.210.020.14.4-4.4-3.54.50.2-2.8-2.9-2.4-2.21.7
Conditioned reinforcement - actives0.00.10.30.40.2-0.10.00.3-0.10.20.50.4-0.3
Conditioned reinforcement - inactives0.30.92.0-1.11.01.4-0.6-1.1-0.9-0.4-0.9-0.81.0
Conditioned locomotion0.81.14.60.8-0.5-1.00.32.20.20.91.11.2-1.2
Patch foraging indifference point 0 sec0.71.95.51.8-2.2-2.41.81.10.3-0.8-0.3-0.1-0.2
Patch foraging indifference point AUC0.20.50.80.8-0.8-0.60.8-0.4-0.8-0.9-0.7-0.70.5
Delay disc. indifference point, 0s delay0.60.71.91.1-1.4-1.01.10.1-0.9-0.5-0.4-0.40.3
Delay disc. indifference point, 16s delay0.81.11.9-0.60.71.3-0.3-1.3-1.4-1.0-1.2-1.11.3
Delay disc. indifference point, 2s delay0.60.71.40.8-0.7-0.20.9-0.5-0.6-1.2-0.9-0.91.0
Delay disc. indifference point, 24s delay0.81.23.5-1.41.51.9-1.2-1.4-0.1-0.2-0.5-0.60.8
Delay disc. indifference point, 4s delay1.41.53.71.1-1.3-0.51.2-0.8-1.9-1.4-1.2-1.21.1
Delay disc. indifference point, 8s delay0.20.30.9-0.60.71.0-0.7-0.3-0.0-0.10.10.00.2
Indifference point function ln k0.10.20.80.3-0.3-0.50.20.90.50.40.40.5-0.4
Indifference point function log k0.10.20.80.3-0.3-0.50.20.90.50.40.40.5-0.4
Patch foraging total patch changes 0 sec0.61.85.41.7-2.1-2.31.71.10.5-0.6-0.10.1-0.4
Patch foraging total patch changes 12 sec0.71.01.91.3-1.4-1.21.3-0.2-0.4-1.2-0.9-0.80.5
Patch foraging total patch changes 18 sec0.40.92.21.4-1.4-1.51.30.30.1-1.0-0.5-0.40.2
Patch foraging total patch changes 24 sec0.41.43.21.4-1.8-1.51.5-0.4-0.6-1.1-1.0-0.90.6
Patch foraging total patch changes 6 sec0.50.92.91.1-1.7-1.71.30.50.1-0.5-0.4-0.2-0.1
Patch foraging time to switch 0 sec0.82.97.4-2.52.72.7-2.5-0.80.51.00.50.5-0.1
Patch foraging water rate 0 sec0.62.36.02.2-2.4-2.42.20.6-0.1-1.0-0.4-0.50.2
Patch foraging water rate 12 sec0.72.96.31.4-1.5-2.50.82.11.71.31.71.6-2.0
Patch foraging water rate 18 sec0.92.05.82.1-2.1-2.41.71.30.10.00.40.3-0.7
Patch foraging water rate 24 sec0.60.91.70.4-0.4-1.00.01.30.51.01.21.1-1.3
Patch foraging water rate 6 sec0.91.32.30.8-0.8-1.50.41.51.00.91.31.2-1.3
Seeking ratio, delayed vs. immediate footshock1.42.04.4-1.92.11.5-1.80.51.31.41.11.0-0.7
Distance traveled before self-admin0.40.92.1-0.60.60.1-0.91.10.71.51.01.1-1.1
Distance traveled after self-admin1.22.14.8-0.50.4-0.5-0.82.21.01.91.71.9-1.8
Extensor digitorum longus weight0.10.20.6-0.50.60.5-0.7-0.7-0.30.50.40.2-0.3
Bone: elastic displacement1.92.44.9-1.71.60.9-1.80.72.21.71.51.4-1.3
Bone: elastic work3.64.79.3-2.12.00.9-2.41.23.02.52.52.3-2.1
Bone: endosteal estimation1.23.04.81.9-1.7-0.82.0-1.0-2.2-1.9-1.8-1.81.7
Bone: endosteal perimeter1.33.15.32.1-2.1-1.42.3-0.5-1.7-1.8-1.7-1.61.5
Epididymis fat weight0.10.71.4-1.00.90.7-1.2-0.41.00.80.70.5-0.6
Delta time in closed arm before/after self-admin0.70.61.8-1.11.01.3-0.9-0.8-0.40.1-0.5-0.50.5
Delta time in open arm before/after self-admin2.12.54.61.9-1.9-1.62.2-0.6-1.9-1.3-1.6-1.21.1
Diff in mean of infusions in LGA sessions1.42.66.1-1.71.42.5-1.0-1.9-1.4-0.8-1.6-1.51.8
Delay discount exponential model param0.30.41.20.7-0.7-1.10.60.60.30.30.20.2-0.5
Extinction: sum of active levers before priming0.10.10.40.3-0.00.20.20.10.1-0.7-0.4-0.30.4
Active lever presses in extinction session 61.21.24.60.6-0.8-1.40.52.11.00.90.71.0-1.1
Bone: final force0.71.12.0-0.60.71.3-0.3-1.4-1.3-0.9-1.0-1.11.3
Bone: final moment0.50.91.7-0.40.41.0-0.1-1.2-1.3-0.8-0.9-1.01.2
Food consumed during 24 hour testing period0.81.74.31.8-1.8-2.11.71.5-0.1-0.20.20.4-0.5
Glucose0.30.51.00.00.3-0.3-0.40.90.80.71.01.0-1.0
Heart weight0.91.43.71.3-1.9-1.41.6-0.1-0.8-1.0-1.2-0.90.7
Delay discount hyperbolic model param0.30.31.00.5-0.5-1.00.50.70.50.40.40.4-0.6
Intermittent access intake day 1-15 change0.42.34.90.3-0.6-1.5-0.02.21.81.81.71.7-1.9
Intermittent access intake escalation0.42.14.50.6-0.9-1.70.32.11.41.61.51.5-1.7
Intermittent access intake escalation 20.30.51.10.3-0.5-0.80.01.00.70.80.80.8-0.9
Intermitt. access day 1 inactive lever presses0.11.44.0-2.01.21.9-1.4-1.30.40.0-0.5-0.70.8
Intermitt. access day 15 inactive lever presses0.00.20.6-0.70.10.5-0.3-0.60.30.3-0.2-0.20.3
Intermitt. access escalation Index0.00.10.30.2-0.00.20.2-0.5-0.3-0.4-0.4-0.50.4
Intermittent access day 1 total infusions0.30.81.71.3-1.1-0.61.1-0.2-1.2-0.9-0.4-0.50.6
Intermittent access day 15 total infusions0.20.51.11.1-1.0-1.10.90.7-0.20.10.40.3-0.3
Intermittent access terminal intake (last 3 days)0.30.51.61.3-1.1-1.01.00.7-0.2-0.20.20.0-0.0
Intermittent access total infusions0.40.51.71.3-0.9-0.90.90.9-0.4-0.30.20.1-0.1
Intermittent access day 1 locomotion0.10.30.70.2-0.10.30.4-0.4-0.6-0.7-0.7-0.60.8
Intermittent access day 15 total locomotion0.20.71.60.10.4-0.4-0.11.11.30.91.11.1-0.9
Intermittent access total locomotion0.20.20.60.7-0.5-0.50.70.80.2-0.10.10.10.0
Intermittent access standard deviation0.10.30.8-0.1-0.4-0.6-0.20.40.10.90.50.5-0.8
Left kidney weight0.10.61.70.8-1.3-1.20.8-0.5-0.8-0.1-0.5-0.4-0.2
Right kidney weight0.31.93.61.1-1.9-1.31.4-1.3-1.9-0.9-1.3-1.30.7
Cocaine induced anxiety0.71.95.4-2.21.92.3-1.6-1.00.80.0-0.5-0.60.9
Post-drug Anxiety1.51.73.6-1.21.51.9-0.5-1.20.3-1.1-1.3-1.41.7
Baseline Anxiety1.32.24.11.8-1.4-1.22.0-0.5-1.6-1.7-1.4-1.31.2
Tail length1.89.914.23.1-3.2-1.63.6-2.0-3.4-3.8-3.5-3.53.1
Length with tail2.08.712.42.7-3.0-1.43.2-2.2-3.3-3.5-3.3-3.32.9
Length without tail0.10.62.10.2-0.6-0.10.5-0.8-1.4-0.6-0.9-0.80.7
Times rat made contact with spout0.20.20.6-0.40.40.7-0.2-0.7-0.4-0.3-0.4-0.50.5
Lifetime Intake0.60.82.41.6-1.1-1.21.11.0-0.5-0.30.30.1-0.1
Liver weight, left0.40.71.7-0.40.51.0-0.3-1.3-1.2-0.6-0.9-0.90.9
Liver weight, right0.71.34.4-0.30.31.0-0.1-2.1-0.8-1.0-1.2-1.51.3
Locomotor activity0.30.41.50.9-1.1-1.20.80.30.10.10.20.2-0.4
Locomotor testing distance0.51.33.31.8-1.8-1.81.60.5-0.6-0.5-0.2-0.2-0.1
Locomotor testing rearing0.20.81.71.3-1.2-0.91.2-0.1-1.0-0.9-0.6-0.70.5
Locomotion in novel chamber0.91.22.0-1.10.80.3-1.11.01.31.41.21.2-1.2
Locomotion in novel chamber post-restriction0.10.40.91.0-0.5-0.90.60.9-0.10.20.40.7-0.6
Fecal boli incidents, locomotor time 10.41.13.0-1.51.61.7-1.4-0.50.80.40.40.20.2
Change in fecal boli incidents, locomotor task0.20.20.90.7-0.4-0.40.50.2-1.0-0.5-0.5-0.10.0
Time >=10cm from walls, locomotor time 10.40.61.20.9-0.6-0.61.10.2-0.5-1.0-0.8-0.60.6
Bouts of movement, locomotor time 10.70.91.90.1-0.20.00.8-1.0-1.2-0.8-1.4-1.31.3
Total resting periods, locomotor time 10.20.20.6-0.30.40.30.2-0.6-0.1-0.3-0.7-0.60.8
Rest time, locomotor task time 10.10.10.40.00.60.40.1-0.00.4-0.4-0.2-0.30.5
Distance moved, locomotor task time 10.00.10.2-0.0-0.3-0.1-0.20.1-0.50.40.30.3-0.4
Vertical activity count, locomotor time 10.00.21.0-0.1-0.20.2-0.1-0.5-1.0-0.1-0.3-0.20.2
Time >=10cm from walls, locomotor time 21.43.96.52.1-1.9-1.12.3-0.6-2.6-2.4-2.1-1.91.8
Bouts of movement, locomotor time 20.82.86.00.7-0.50.70.9-1.9-2.5-1.9-2.0-2.12.2
Total resting periods, locomotor time 20.51.93.70.20.21.10.3-1.8-1.9-1.5-1.6-1.71.8
Rest time, locomotor task time 21.22.04.4-1.72.11.6-1.9-0.31.61.11.00.8-0.6
Distance moved, locomotor task time 21.11.53.21.8-1.7-1.61.80.5-1.1-1.0-0.7-0.60.4
Vertical activity count, locomotor time 20.40.93.10.7-0.70.00.7-0.6-1.8-1.3-1.1-1.01.0
Light reinforcement 10.73.25.2-2.01.91.2-2.30.42.22.01.81.6-1.6
Light reinforcement 22.04.47.9-0.50.6-0.7-1.22.42.42.62.82.7-2.8
Bone: marrow area1.12.74.41.7-1.5-0.71.8-1.1-2.1-1.8-1.8-1.71.6
Bone: maximum diameter1.22.44.62.1-2.1-1.62.1-0.2-1.4-1.5-1.2-1.21.0
Bone: maximum force0.20.30.7-0.40.50.8-0.3-0.7-0.9-0.3-0.4-0.50.7
Bone: maximum moment0.10.20.6-0.10.30.5-0.1-0.5-0.8-0.2-0.2-0.40.5
Mean time between licks in bursts1.38.111.42.8-3.0-1.73.4-1.8-3.1-3.3-3.1-3.02.7
Mean num. licks in bursts0.72.04.62.1-1.9-1.92.11.1-0.9-1.0-0.7-0.50.4
Cd content in liver0.30.40.9-0.20.40.8-0.0-0.9-0.2-0.7-0.6-0.70.9
Co content in liver2.12.44.11.6-1.4-0.61.8-1.0-1.5-2.0-1.7-1.81.7
Cu content in liver1.51.83.21.0-1.0-0.31.2-1.1-1.8-1.6-1.6-1.51.5
Fe content in liver0.00.00.1-0.20.20.3-0.1-0.2-0.2-0.2-0.2-0.20.3
K content in liver0.30.20.8-0.70.50.7-0.5-0.9-0.0-0.0-0.2-0.30.2
Mg content in liver0.10.10.3-0.0-0.1-0.4-0.10.30.40.40.40.4-0.6
Mn content in liver2.02.23.3-1.61.60.9-1.80.91.51.81.61.6-1.4
Na content in liver0.50.51.70.8-0.8-1.10.71.3-0.10.30.30.5-0.5
Rb content in liver0.30.30.80.3-0.10.20.6-0.2-0.3-0.9-0.7-0.70.9
Se content in liver3.23.78.3-2.92.92.6-2.8-0.11.11.61.11.1-0.6
Sr content in liver1.71.43.10.4-0.5-1.30.01.81.11.31.41.5-1.6
Zn content in liver1.21.43.41.8-1.8-1.81.60.6-0.7-0.5-0.3-0.2-0.1
Bone: minimum diameter1.12.24.71.1-1.2-0.41.4-1.3-2.2-1.6-1.6-1.71.6
Time in familiar zone, hab. session 10.10.10.30.6-0.4-0.50.30.20.2-0.00.20.1-0.2
Time in novel zone, hab. session 10.30.40.7-0.60.30.7-0.2-0.8-0.5-0.4-0.7-0.70.7
Total zone transitions, hab. session 10.30.51.40.4-0.2-0.60.11.20.50.80.80.8-0.8
Total locomotion distance, hab. session 10.81.13.5-0.1-0.10.60.2-1.9-0.9-1.2-1.2-1.41.2
Locomotion velocity, hab. session 10.50.72.7-0.10.10.6-0.0-1.6-0.6-0.8-0.9-1.00.9
Time in familiar zone, hab. session 22.22.54.42.0-2.0-1.52.1-0.7-1.3-1.7-1.4-1.41.2
Time in novel zone, hab. session 22.32.54.2-1.41.40.6-1.71.21.62.11.81.8-1.7
Total zone transitions, hab. session 21.31.74.81.8-1.9-2.21.61.50.00.10.20.4-0.7
Total locomotion distance, hab. session 21.11.42.31.0-1.2-0.61.1-1.5-1.2-1.3-1.3-1.41.0
Locomotion velocity, hab. session 21.11.52.70.9-1.1-0.41.0-1.7-1.3-1.4-1.4-1.51.1
Novel to familiar place preference ratio2.02.65.10.2-0.50.51.0-1.9-1.7-2.0-2.3-2.12.1
Novelty place preference1.82.34.40.3-0.60.41.0-1.8-1.6-1.8-2.1-2.02.0
Time in novel zone, NPP test2.22.64.90.5-0.80.31.2-1.8-1.7-2.0-2.2-2.12.1
Total zone transitions, NPP test1.11.73.00.00.1-0.8-0.41.61.51.61.61.7-1.7
Total locomotion distance, NPP test0.20.30.6-0.50.40.2-0.7-0.80.80.50.50.3-0.6
Locomotion velocity, NPP test0.40.61.1-0.80.70.4-1.1-0.71.00.80.70.5-0.8
Intraocular pressure0.20.41.4-0.30.3-0.1-0.21.20.50.70.60.9-0.7
Delta distance traveled before/after self-admin0.60.61.61.2-1.0-0.91.20.5-0.6-0.7-0.3-0.30.3
Delta ambulatory time before/after self-admin0.30.51.21.1-0.8-0.91.10.5-0.5-0.6-0.1-0.10.1
Parametrial fat weight1.53.56.5-1.11.20.1-1.71.62.02.32.52.4-2.4
Pavlov. Cond. lever latency0.60.71.3-1.00.80.5-1.1-0.10.91.10.90.8-0.9
Pavlov. Cond. magazine entry latency1.82.35.52.3-2.2-2.12.20.8-1.1-1.1-0.6-0.50.3
Pavlov. Cond. change in total contacts1.51.62.61.3-1.1-0.51.6-0.2-1.5-1.6-1.4-1.31.4
Pavlov. Cond. index score1.21.53.61.9-1.5-1.41.80.6-1.1-1.2-0.7-0.70.6
Pavlov. Cond. latency score1.21.53.11.7-1.4-1.21.80.4-1.1-1.3-0.9-0.80.8
Pavlov. Cond. lever contacts0.50.61.31.1-0.9-0.71.10.3-0.8-0.9-0.6-0.50.5
Pavlov. Cond. magazine entry number1.72.24.8-2.22.01.8-2.2-0.71.21.30.90.7-0.6
Pavlov. Cond. intertrial magazine entries0.40.51.4-1.11.11.2-0.9-0.50.20.1-0.1-0.10.3
Pavlov. Cond. lever-magazine prob. diff.1.01.33.01.7-1.4-1.21.70.6-1.0-1.1-0.7-0.60.6
Pavlov. Cond. response bias0.70.92.31.5-1.3-1.31.40.6-0.7-0.7-0.4-0.30.2
Pavlov. Cond. lever latency8.712.330.3-5.55.35.4-5.0-2.11.51.60.80.60.1
Pavlov. Cond. magazine entry latency2.73.910.12.2-2.2-3.21.52.41.01.01.61.5-2.0
Pavlov. Cond. change in total contacts4.410.726.05.1-4.9-5.14.62.2-1.3-1.5-0.7-0.5-0.2
Pavlov. Cond. index score5.58.622.94.6-4.4-4.83.92.2-0.7-0.8-0.10.0-0.7
Pavlov. Cond. latency score4.67.420.54.2-4.1-4.53.62.3-0.4-0.50.20.3-0.9
Pavlov. Cond. lever contacts7.911.628.05.3-5.2-5.24.91.8-1.6-1.8-1.1-0.80.1
Pavlov. Cond. magazine entry number4.05.215.1-3.13.13.9-2.5-2.6-0.2-0.3-0.9-1.01.5
Pavlov. Cond. intertrial magazine entries1.12.44.20.6-0.70.31.1-1.6-1.7-2.0-2.1-2.02.0
Pavlov. Cond. lever-magazine prob. diff.5.48.321.94.5-4.4-4.73.92.1-0.9-0.9-0.2-0.1-0.6
Pavlov. Cond. response bias8.511.830.35.3-5.3-5.54.82.4-1.2-1.3-0.5-0.3-0.5
Time in closed arm before self-admin0.81.34.51.8-1.5-2.11.60.70.2-0.50.20.2-0.5
Time in closed arm after self-admin0.30.30.8-0.90.90.8-0.7-0.30.00.20.00.00.1
Time in open arm before self-admin3.34.08.1-2.92.32.3-2.8-0.12.41.81.41.2-1.0
Time in open arm after self-admin0.20.20.40.3-0.6-0.20.5-0.6-0.2-0.4-0.6-0.50.5
Bone: periosteal estimation0.51.32.11.4-1.2-0.71.3-0.6-1.5-1.1-1.0-1.11.0
Bone: periosteal perimeter0.61.22.41.5-1.6-1.21.5-0.2-1.1-0.8-0.8-0.80.6
Bone: post-yield work0.10.10.30.5-0.4-0.30.30.0-0.5-0.2-0.0-0.10.0
Progressive ratio test 1 active lever presses0.00.00.20.10.20.20.10.5-0.2-0.00.10.10.1
Progressive ratio test 1 breakpoint0.00.10.30.10.20.20.00.6-0.2-0.10.10.10.1
Progressive ratio test 1 inactive lever presses0.10.30.9-0.80.90.9-0.7-0.10.40.20.10.10.1
Progressive ratio test 2 active lever presses0.10.10.40.4-0.00.00.30.3-0.7-0.3-0.0-0.10.2
Progressive ratio test 2 breakpoint0.10.10.50.5-0.1-0.00.40.3-0.7-0.3-0.0-0.00.2
Progressive ratio test 2 inactive lever presses0.00.10.20.00.30.0-0.20.4-0.20.40.50.5-0.4
Incentive Sensitization - Responses0.10.20.80.6-0.4-0.20.40.1-0.9-0.4-0.1-0.10.2
Incentive Sensitization - Breakpoint0.10.10.50.5-0.3-0.20.30.3-0.7-0.10.20.2-0.1
Sum of active levers in priming session hrs 5-60.30.31.20.3-0.4-0.60.11.10.30.20.40.4-0.5
Progressive ratio0.51.32.50.5-0.5-1.40.31.41.61.21.11.3-1.4
Food seeking constrained by brief footshock1.31.63.21.8-1.5-1.51.8-0.6-1.0-1.1-1.1-1.00.6
Seeking ratio, punishment vs. effort0.71.63.51.0-0.8-0.01.0-1.2-1.9-1.7-1.3-1.51.3
Retroperitoneal fat weight0.42.04.5-1.92.01.9-2.1-1.60.90.70.70.2-0.4
Reaction time number correct0.10.30.6-0.10.2-0.2-0.30.70.70.40.80.7-0.7
Reaction time mean minus median0.10.60.80.8-0.9-0.50.9-0.6-0.8-0.6-0.7-0.90.7
Reaction time mean minus median AUC0.00.30.60.7-0.7-0.50.8-0.1-0.6-0.4-0.4-0.50.4
Reaction time num false alarms1.22.15.7-1.92.02.4-1.5-1.90.5-0.3-0.5-0.70.9
Reaction time num false alarms AUC0.81.85.0-1.82.02.2-1.6-1.50.70.0-0.2-0.30.6
Reaction time trials correct on left0.10.30.6-0.10.2-0.2-0.30.70.70.40.80.7-0.7
Reaction time trials on left0.10.30.7-0.10.3-0.2-0.30.70.80.50.90.7-0.7
Reaction time mean0.92.04.8-1.31.52.2-1.1-2.2-1.2-0.6-0.9-1.11.3
Reaction time mean AUC0.92.15.4-1.51.72.3-1.2-2.1-1.1-0.5-0.8-1.01.2
Median of all reaction times1.62.57.0-1.82.12.7-1.6-2.2-1.0-0.3-0.6-0.91.1
Reaction time omissions0.20.30.7-0.70.80.8-0.7-0.6-0.00.20.20.0-0.0
Reaction time false alarm rate1.21.74.6-1.81.92.2-1.5-1.60.50.0-0.3-0.40.6
Reaction time premature initiation rate1.42.13.91.7-1.8-1.21.7-0.7-2.0-1.4-1.3-1.41.0
Reaction time premature initiations0.30.91.81.3-1.3-1.11.2-0.2-1.3-0.8-0.5-0.60.3
Std. dev. reaction times0.51.73.30.10.00.90.4-1.8-1.8-1.4-1.5-1.71.7
Reaction time trials completed0.10.30.7-0.10.3-0.2-0.30.70.80.50.90.7-0.7
Reaction time trials AUC0.00.20.4-0.10.2-0.2-0.20.40.60.30.60.5-0.5
Run reversals in cocaine runway, females0.40.51.20.7-1.1-0.60.8-0.3-0.2-0.6-0.6-0.80.4
Run reversals in cocaine runway, males0.30.30.8-0.80.90.8-0.7-0.1-0.10.4-0.10.20.0
Latency to leave start box in cocaine runway0.60.82.8-1.31.31.7-1.4-0.10.0-0.10.0-0.10.3
Latency to leave start box in cocaine runway, F0.91.13.0-1.00.91.7-0.9-1.1-0.4-1.0-0.9-1.11.2
Latency to leave start box in cocaine runway, M1.11.01.7-0.81.00.5-1.21.10.51.11.21.3-1.1
Std. dev. time between licks in bursts1.73.24.61.3-1.4-0.51.6-1.9-2.0-2.1-2.1-2.11.9
Total sessions with >9 infusions0.81.03.92.0-1.3-1.31.30.6-0.3-0.60.30.0-0.1
Short access day 1 total inactive lever presses0.20.51.7-0.3-0.10.50.0-1.3-0.4-0.7-0.7-0.80.9
Short access day 10 total inactive lever presses0.21.33.0-1.71.31.6-1.3-1.41.00.1-0.3-0.30.5
Short access day 1 total infusions1.12.25.12.3-1.9-1.31.9-0.8-1.8-1.5-0.8-1.00.8
Short access day 10 total infusions0.50.82.71.6-1.3-1.21.10.8-0.2-0.40.40.1-0.2
Short access total infusions1.01.33.82.0-1.7-1.41.60.5-1.1-0.8-0.1-0.30.2
Short access day 1 locomotion0.30.51.30.9-1.2-1.00.70.8-0.40.20.50.4-0.4
Short access day 10 total locomotion0.10.40.80.7-0.9-0.90.50.7-0.10.20.50.5-0.6
Short access total locomotion0.20.41.70.3-0.1-0.30.11.30.30.50.80.7-0.6
One hour access (0.3 mA shock)0.30.41.40.7-0.3-0.80.31.2-0.30.30.50.6-0.7
Compulsive drug intake0.81.12.2-1.51.10.4-1.2-0.51.01.40.81.1-1.0
One hour access (shock baseline)0.51.34.71.5-1.2-1.41.02.2-0.7-0.00.50.4-0.6
Social response proportion0.20.31.2-0.90.20.4-0.5-1.10.10.1-0.3-0.30.1
Social responses0.60.83.1-0.50.20.7-0.2-1.8-0.8-0.8-1.0-1.00.9
Social time1.21.94.4-1.82.11.8-2.0-0.30.91.01.00.9-0.6
Soleus weight0.31.03.6-0.50.51.0-0.3-1.9-0.8-0.9-1.0-1.11.0
Bone: stiffness1.22.24.6-0.80.81.7-0.3-2.1-1.7-1.4-1.5-1.61.8
Tibialis anterior weight0.10.51.10.4-0.30.10.4-1.0-0.8-0.7-0.7-0.90.8
Time to tail flick, vehicle, before self-admin0.60.82.30.7-1.1-1.50.80.31.40.30.70.5-0.7
Time to tail flick, vehicle, after self-admin0.30.61.31.1-0.7-0.51.1-0.20.1-0.9-0.7-0.60.7
Time to tail flick, test, before self-admin2.52.95.41.8-2.2-1.52.3-0.8-1.2-1.7-1.8-1.61.4
Time to tail flick, test, after self-admin3.13.35.81.2-1.6-0.51.8-1.3-2.4-2.0-2.3-2.22.0
Delta time to tail flick, vehicle, before/after SA0.20.30.60.10.20.7-0.0-0.2-0.8-0.5-0.7-0.50.7
Delta time to tail flick, test, before/after SA0.40.51.3-1.11.01.0-1.1-0.20.00.70.40.3-0.3
Tibia length0.30.91.81.3-1.1-1.01.30.8-1.3-0.6-0.6-0.30.4
Ambulatory time before self-admin0.30.91.8-0.70.80.4-1.10.80.61.31.11.1-1.0
Ambulatory time after self-admin0.81.25.10.30.0-0.7-0.12.20.11.21.31.4-1.3
Bone: tissue strength2.52.64.5-0.91.10.1-1.31.61.82.12.12.0-1.9
Total heroin consumption0.20.30.60.4-0.6-0.70.20.7-0.20.40.40.5-0.6
Bone: trabecular number0.91.82.5-1.41.61.0-1.60.91.51.41.41.4-1.1
Bone: trabecular spacing0.50.71.40.6-0.6-1.10.31.20.50.40.80.9-1.1
Bone: trabecular thickness1.01.42.8-0.20.10.90.2-1.5-1.5-1.3-1.4-1.51.7
Bone: trabecular tissue density2.34.19.6-1.10.92.2-0.4-3.1-2.0-1.8-2.2-2.42.5
Water consumed over 24 hours0.10.20.4-0.60.50.5-0.5-0.30.30.30.10.1-0.1
Number of responses in last shaping day1.21.62.8-0.80.91.7-0.4-1.4-1.4-1.2-1.4-1.41.6