Hub : Genes

LOC120099888

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression LOC120099888 0.08 0.05 4.0e-07 0.05 0.05 0.05 0.05 7.2e-06 2.5e-06 4.2e-06 7.4e-06
2 Adipose gene expression LOC120099888 0.2 0.1 4.6e-14 0.11 0.11 0.1 0.11 4.2e-12 2.8e-12 1.2e-11 4.4e-12
3 Adipose alternative TSS XR_005499324.1 0.27 0.12 0.0e+00 0.13 0.12 0.12 0.14 2.6e-14 1.8e-13 4.5e-13 8.8e-15
4 Adipose alternative TSS XR_005499327.1 0.26 0.11 5.6e-17 0.13 0.12 0.11 0.13 1.8e-14 2.6e-13 1.4e-12 1.1e-14
5 Adipose alternative polyA XR_005499327.1 0.03 0.02 1.1e-03 0.02 0.01 0.02 0.01 2.2e-03 2.2e-02 6.0e-03 1.3e-02
6 Adipose alternative polyA XR_005499324.1 0.03 0.02 1.6e-03 0.02 0.01 0.02 0.01 1.6e-03 2.8e-02 6.6e-03 7.4e-03
7 PL alternative polyA XR_005499324.1 0.14 0.08 1.0e-12 0.12 0.12 0.12 0.12 2.1e-13 4.7e-13 1.2e-12 3.0e-13
8 PL alternative polyA XR_005499327.1 0.12 0.07 1.3e-10 0.1 0.1 0.08 0.1 1.5e-11 1.3e-10 4.4e-09 4.6e-11
9 NAcc alternative polyA XR_005499324.1 0.04 0.03 9.9e-06 0.03 0.04 0.03 0.03 5.2e-04 4.8e-05 1.3e-04 4.3e-04
10 NAcc alternative polyA XR_005499327.1 0.05 0.03 5.1e-06 0.01 0.04 0.03 0.03 8.3e-03 3.7e-05 1.0e-04 4.2e-04
11 Liver alternative TSS XR_005499327.1 0.03 0.03 1.9e-03 0.01 0.02 0.02 0.01 1.9e-02 4.5e-03 4.3e-03 1.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.00.10.20.2-0.2-0.10.1-0.20.20.5-0.5-0.0-0.1-0.3
Area under the delay curve0.00.00.0-0.10.10.1-0.1-0.10.1-0.10.10.1-0.0-0.0
BMI with tail0.00.00.10.30.1-0.00.0-0.00.00.1-0.10.2-0.2-0.2
BMI without tail1.12.45.0-0.5-0.8-1.41.4-1.61.6-1.11.12.0-2.1-2.2
Body weight0.41.64.0-0.3-0.4-1.11.1-1.01.0-1.11.11.8-1.8-2.0
Weight adjusted by age1.11.31.9-0.7-0.8-1.11.1-1.01.0-1.21.21.3-1.4-1.4
Bone surface1.93.44.4-1.5-2.0-2.02.0-2.02.0-1.31.31.8-1.9-2.1
Bone volume1.11.82.8-1.0-1.5-1.41.4-1.51.5-0.90.91.4-1.4-1.7
Breakpoint value in progressive ratio session0.30.40.60.50.50.6-0.60.6-0.60.6-0.6-0.70.70.7
Number of licking bursts4.35.17.02.72.62.2-2.22.3-2.32.4-2.4-1.91.91.6
Context. condit. distance diff. score2.63.15.1-2.1-2.2-2.12.1-1.91.9-1.41.41.4-1.3-1.2
Locomotion velocity, session 11.01.12.10.60.91.1-1.11.1-1.10.7-0.7-1.21.31.4
Locomotion distance, session 10.20.20.6-0.8-0.4-0.20.2-0.10.1-0.80.8-0.00.10.5
Locomotion velocity, session 20.00.00.10.00.30.3-0.30.0-0.0-0.30.3-0.10.10.3
Locomotion distance, session 20.10.10.4-0.5-0.3-0.20.2-0.20.2-0.60.60.2-0.10.1
Locomotion velocity, session 30.20.20.5-0.7-0.7-0.40.4-0.40.4-0.60.60.00.00.3
Locomotion distance, session 30.30.41.1-1.0-0.9-0.50.5-0.50.5-0.80.80.1-0.00.3
Stereotopy head waving bouts, day 30.10.20.40.60.70.5-0.50.5-0.50.2-0.2-0.10.10.1
Stereotopy head waving duration, day 30.10.20.3-0.5-0.6-0.40.4-0.40.4-0.30.30.3-0.3-0.3
Locomotion velocity, session 70.30.40.50.50.40.5-0.50.6-0.60.7-0.7-0.70.70.7
Locomotion distance, session 70.00.10.20.30.20.1-0.10.2-0.20.4-0.4-0.10.10.0
Stereotopy head waving bouts, day 71.31.42.8-1.5-1.3-1.01.0-1.11.1-1.71.70.9-0.8-0.5
Stereotopy head waving duration, day 72.32.84.3-1.9-1.7-1.51.5-1.71.7-2.12.11.4-1.4-1.1
Locomotion velocity, session 81.41.62.5-1.4-1.6-1.41.4-1.31.3-0.80.81.2-1.2-1.3
Locomotion distance, session 81.52.33.6-1.9-1.8-1.61.6-1.51.5-1.71.71.2-1.1-0.8
Degree of sensitization distance0.20.21.00.50.4-0.20.2-0.10.10.2-0.20.6-0.7-1.0
Degree of sensitization stereotypy3.13.46.0-2.3-2.0-1.61.6-1.81.8-2.52.51.4-1.3-0.8
Conditioned locomotion0.10.10.10.10.00.2-0.20.2-0.20.2-0.2-0.40.40.4
Cocaine response after cond. corrected1.61.83.11.61.81.4-1.41.3-1.31.3-1.3-1.11.11.0
Cocaine response after cond. not corrected0.80.91.41.01.21.0-1.01.0-1.00.8-0.8-0.90.90.8
Cocaine response before conditioning0.60.71.6-1.3-1.2-0.80.8-0.70.7-0.90.90.6-0.5-0.3
Saline control response2.02.63.4-1.5-1.4-1.61.6-1.51.5-1.81.81.7-1.7-1.6
Bone: connectivity density0.20.30.8-0.4-0.9-0.70.7-0.80.80.1-0.10.3-0.4-0.6
Bone: cortical apparent density0.91.22.01.41.31.1-1.11.2-1.21.2-1.2-0.70.60.4
Bone: cortical area1.11.72.9-0.9-1.2-1.41.4-1.51.5-0.80.81.4-1.4-1.7
Bone: cortical porosity0.40.41.1-1.1-0.9-0.60.6-0.60.6-0.80.80.3-0.2-0.0
Bone: cortical porosity0.20.20.7-0.8-0.6-0.30.3-0.30.3-0.60.60.10.00.3
Bone: cortical thickness0.10.10.40.40.20.3-0.30.3-0.30.6-0.6-0.30.30.1
Bone: cortical thickness0.00.00.1-0.4-0.3-0.20.20.1-0.1-0.30.3-0.00.00.1
Bone: cortical tissue density1.01.32.11.41.41.2-1.21.2-1.21.2-1.2-0.80.70.5
Condit. Reinf. active minus inactive responses0.50.61.0-0.4-0.5-0.70.7-0.70.7-0.70.70.9-0.9-1.0
Condit. Reinf. active-inactive response ratio1.71.83.0-0.9-1.2-1.41.4-1.41.4-1.01.01.5-1.6-1.7
Condit. Reinf. active responses0.00.00.10.00.0-0.10.1-0.10.1-0.30.30.3-0.3-0.3
Condit. Reinf. inactive responses0.30.40.80.40.60.8-0.80.7-0.70.2-0.2-0.60.70.9
Incentive salience index mean0.40.50.7-0.5-0.5-0.60.6-0.60.6-0.80.80.8-0.9-0.8
Condit. Reinf. lever presses0.10.10.3-0.3-0.3-0.30.3-0.30.3-0.60.60.4-0.4-0.1
Condit. Reinf. active minus inactive responses7.79.512.4-3.1-2.9-3.03.0-2.92.9-3.53.53.1-3.0-2.8
Condit. Reinf. active-inactive response ratio1.11.22.4-1.3-1.0-1.01.0-0.90.9-1.61.60.9-0.9-0.7
Condit. Reinf. active responses11.015.217.9-3.8-3.6-3.83.8-3.73.7-4.24.24.0-4.0-3.9
Condit. Reinf. inactive responses7.18.710.7-2.7-2.7-2.92.9-2.82.8-3.03.03.2-3.2-3.3
Condit. Reinf. lever presses21.028.431.7-5.6-5.5-5.55.5-5.45.4-5.45.45.1-5.0-4.8
Condit. Reinf. lever reinforcers received11.916.719.9-4.1-3.9-4.04.0-3.93.9-4.54.54.1-4.1-3.9
Conditioned reinforcement - actives1.21.22.3-1.5-1.4-1.11.1-1.11.1-1.11.10.7-0.6-0.4
Conditioned reinforcement - inactives0.70.71.00.91.00.9-0.91.0-1.00.8-0.8-0.80.80.6
Conditioned locomotion0.40.51.4-1.2-1.1-0.60.6-0.60.6-0.70.70.2-0.10.0
Patch foraging indifference point 0 sec6.610.612.4-3.5-3.5-3.43.4-3.43.4-3.13.13.1-3.0-2.9
Patch foraging indifference point AUC0.30.40.7-0.3-0.2-0.60.6-0.70.7-0.50.50.7-0.8-0.8
Delay disc. indifference point, 0s delay0.60.61.2-0.9-0.6-0.60.6-0.80.8-1.11.10.8-0.7-0.5
Delay disc. indifference point, 16s delay0.20.20.30.30.40.5-0.50.4-0.40.5-0.5-0.50.50.5
Delay disc. indifference point, 2s delay0.91.01.5-1.1-0.7-0.80.9-1.01.0-1.21.21.0-0.9-0.7
Delay disc. indifference point, 24s delay0.90.81.41.10.90.8-0.80.8-0.81.2-1.2-0.80.80.5
Delay disc. indifference point, 4s delay0.40.51.7-0.6-0.1-0.20.2-0.30.3-1.31.30.7-0.6-0.4
Delay disc. indifference point, 8s delay0.30.30.4-0.6-0.5-0.60.6-0.60.6-0.40.40.5-0.5-0.5
Indifference point function ln k0.50.71.9-1.4-1.3-0.80.8-0.80.8-0.70.70.4-0.4-0.1
Indifference point function log k0.50.71.9-1.4-1.3-0.80.8-0.80.8-0.70.70.4-0.4-0.1
Patch foraging total patch changes 0 sec5.38.69.8-3.1-3.1-3.13.1-3.13.1-2.82.82.8-2.7-2.6
Patch foraging total patch changes 12 sec3.24.25.1-1.7-1.8-2.12.1-2.32.3-1.91.92.1-2.1-2.2
Patch foraging total patch changes 18 sec3.54.55.3-1.9-2.0-2.12.1-2.32.3-2.02.02.2-2.2-2.1
Patch foraging total patch changes 24 sec0.70.91.6-0.8-0.6-0.80.8-0.90.9-1.31.31.0-0.9-0.8
Patch foraging total patch changes 6 sec1.62.33.1-1.6-1.7-1.81.8-1.71.7-1.21.21.3-1.3-1.4
Patch foraging time to switch 0 sec5.17.88.32.82.92.9-2.92.8-2.82.8-2.8-2.82.82.7
Patch foraging water rate 0 sec3.65.86.8-2.6-2.6-2.52.5-2.52.5-2.42.42.2-2.2-2.0
Patch foraging water rate 12 sec1.62.53.7-1.9-1.9-1.61.6-1.61.6-1.61.61.3-1.3-1.2
Patch foraging water rate 18 sec0.91.21.5-1.1-1.1-1.11.1-1.11.1-1.21.21.1-1.1-1.0
Patch foraging water rate 24 sec0.40.51.4-1.2-1.2-0.70.7-0.70.7-0.60.60.3-0.2-0.0
Patch foraging water rate 6 sec0.40.61.4-1.1-1.2-0.90.9-0.70.7-0.60.60.6-0.6-0.5
Seeking ratio, delayed vs. immediate footshock2.42.73.11.71.61.7-1.71.8-1.81.6-1.6-1.71.71.5
Distance traveled before self-admin0.40.40.60.80.70.6-0.60.7-0.70.8-0.8-0.50.50.3
Distance traveled after self-admin2.32.53.11.31.31.6-1.61.7-1.71.5-1.5-1.81.81.7
Extensor digitorum longus weight0.10.51.60.2-0.1-0.60.6-0.60.6-0.00.00.9-1.0-1.3
Bone: elastic displacement2.12.33.51.51.31.4-1.41.5-1.51.9-1.9-1.61.51.3
Bone: elastic work2.22.84.01.61.41.5-1.51.6-1.62.0-2.0-1.81.81.6
Bone: endosteal estimation2.14.65.8-1.6-1.7-2.22.2-2.32.3-2.02.02.4-2.4-2.4
Bone: endosteal perimeter3.06.27.1-2.1-2.2-2.52.6-2.62.6-2.42.42.6-2.6-2.7
Epididymis fat weight0.10.20.80.90.80.3-0.30.4-0.4-0.10.10.3-0.4-0.5
Delta time in closed arm before/after self-admin0.20.20.70.50.4-0.10.1-0.10.10.1-0.10.6-0.7-0.8
Delta time in open arm before/after self-admin3.02.93.1-1.7-1.8-1.71.7-1.71.7-1.71.71.7-1.7-1.7
Diff in mean of infusions in LGA sessions2.83.14.32.12.11.8-1.81.7-1.71.7-1.7-1.71.61.5
Delay discount exponential model param0.00.00.1-0.0-0.2-0.20.2-0.00.00.0-0.00.0-0.0-0.1
Extinction: sum of active levers before priming0.20.20.30.50.60.4-0.40.4-0.40.3-0.3-0.30.30.3
Active lever presses in extinction session 61.21.23.1-1.8-1.6-1.11.1-1.01.0-1.21.20.5-0.4-0.1
Bone: final force0.20.20.6-0.2-0.5-0.60.6-0.60.60.2-0.20.4-0.4-0.8
Bone: final moment0.30.51.1-0.4-0.7-0.80.8-0.80.8-0.10.10.7-0.7-1.0
Food consumed during 24 hour testing period2.12.64.5-1.9-1.7-1.31.3-1.51.5-2.12.11.4-1.3-1.0
Glucose0.00.10.10.10.20.3-0.30.3-0.30.2-0.2-0.30.30.3
Heart weight1.01.52.0-1.3-1.4-1.31.3-1.31.3-1.11.11.1-1.1-1.1
Delay discount hyperbolic model param0.00.00.10.2-0.10.0-0.00.2-0.20.3-0.3-0.20.20.1
Intermittent access intake day 1-15 change0.80.81.6-1.3-1.1-0.91.0-1.01.0-0.80.80.6-0.6-0.6
Intermittent access intake escalation1.11.12.0-1.4-1.3-1.11.1-1.21.2-1.01.00.8-0.7-0.7
Intermittent access intake escalation 20.60.60.8-0.9-0.8-0.80.8-0.90.9-0.70.70.7-0.7-0.7
Intermitt. access day 1 inactive lever presses0.70.71.00.91.00.9-0.91.0-1.00.7-0.7-0.70.70.6
Intermitt. access day 15 inactive lever presses0.20.20.40.20.20.5-0.50.5-0.50.3-0.3-0.50.50.7
Intermitt. access escalation Index0.20.20.3-0.4-0.5-0.50.5-0.40.4-0.30.30.4-0.4-0.4
Intermittent access day 1 total infusions0.70.81.3-0.8-0.9-0.90.9-0.90.9-0.80.81.0-1.0-1.1
Intermittent access day 15 total infusions1.21.31.9-1.4-1.4-1.21.2-1.21.2-1.01.01.0-0.9-1.0
Intermittent access terminal intake (last 3 days)1.11.31.6-1.2-1.3-1.11.2-1.21.2-1.01.01.0-1.0-1.1
Intermittent access total infusions0.60.60.8-0.8-0.9-0.80.8-0.80.8-0.70.70.8-0.8-0.9
Intermittent access day 1 locomotion0.00.00.10.0-0.00.2-0.20.2-0.20.2-0.2-0.20.20.1
Intermittent access day 15 total locomotion0.70.71.3-1.1-1.2-0.80.9-0.90.9-0.80.80.6-0.6-0.5
Intermittent access total locomotion0.30.30.5-0.6-0.7-0.60.6-0.60.6-0.50.50.5-0.5-0.6
Intermittent access standard deviation0.10.10.2-0.2-0.2-0.20.2-0.30.3-0.40.40.4-0.4-0.5
Left kidney weight1.54.15.5-1.5-1.4-1.91.9-1.91.9-2.22.22.3-2.3-2.3
Right kidney weight0.92.53.4-1.1-1.0-1.41.4-1.51.5-1.81.81.8-1.8-1.8
Cocaine induced anxiety2.02.32.71.71.71.5-1.51.5-1.51.5-1.5-1.41.41.5
Post-drug Anxiety0.40.50.70.80.90.7-0.70.7-0.70.7-0.7-0.60.60.6
Baseline Anxiety2.12.22.5-1.6-1.5-1.51.5-1.51.5-1.41.41.5-1.4-1.4
Tail length3.410.217.2-1.9-2.0-2.93.0-3.13.1-3.13.13.9-4.0-4.1
Length with tail1.03.67.5-0.8-0.8-1.61.6-1.51.5-2.02.02.5-2.6-2.7
Length without tail0.51.11.60.81.01.1-1.11.3-1.30.8-0.8-1.11.11.1
Times rat made contact with spout0.10.10.30.50.40.2-0.20.2-0.20.1-0.10.3-0.3-0.4
Lifetime Intake0.80.91.0-1.0-1.0-0.90.9-1.01.0-0.80.80.9-0.9-1.0
Liver weight, left0.10.20.70.90.80.4-0.40.4-0.40.3-0.30.2-0.3-0.6
Liver weight, right0.61.02.91.71.71.0-1.01.0-1.00.7-0.7-0.10.0-0.3
Locomotor activity1.01.52.2-1.3-1.5-1.21.2-1.11.1-1.21.21.2-1.2-1.3
Locomotor testing distance2.64.45.2-2.0-2.2-2.12.1-1.91.9-2.32.32.1-2.1-2.1
Locomotor testing rearing1.52.33.1-1.1-1.2-1.41.4-1.41.4-1.61.61.7-1.7-1.7
Locomotion in novel chamber0.40.51.3-1.1-1.2-0.70.7-0.60.6-0.60.60.3-0.3-0.3
Locomotion in novel chamber post-restriction1.51.83.9-2.0-1.8-1.41.4-1.41.4-1.31.30.8-0.7-0.4
Fecal boli incidents, locomotor time 10.40.41.1-0.9-0.9-0.50.5-0.40.4-1.01.00.3-0.3-0.2
Change in fecal boli incidents, locomotor task1.71.62.81.31.31.3-1.31.1-1.11.7-1.7-1.11.11.1
Time >=10cm from walls, locomotor time 10.90.92.0-1.4-1.3-1.01.0-0.90.9-0.80.80.7-0.6-0.4
Bouts of movement, locomotor time 10.00.00.1-0.2-0.00.1-0.10.0-0.0-0.20.2-0.00.10.2
Total resting periods, locomotor time 10.10.20.50.10.20.4-0.40.4-0.40.2-0.2-0.50.50.7
Rest time, locomotor task time 11.11.21.80.71.01.2-1.21.2-1.20.7-0.7-1.11.21.4
Distance moved, locomotor task time 11.51.73.1-0.7-1.1-1.41.4-1.41.4-0.80.81.4-1.5-1.8
Vertical activity count, locomotor time 12.32.43.4-1.1-1.4-1.71.7-1.71.7-1.01.01.6-1.7-1.8
Time >=10cm from walls, locomotor time 20.80.81.5-1.1-0.9-0.80.8-0.80.8-1.21.20.8-0.8-0.6
Bouts of movement, locomotor time 20.40.50.6-0.7-0.4-0.70.7-0.70.7-0.70.70.7-0.7-0.5
Total resting periods, locomotor time 20.10.10.2-0.4-0.1-0.30.4-0.40.4-0.40.40.4-0.4-0.2
Rest time, locomotor task time 22.83.24.41.91.81.7-1.71.8-1.82.1-2.1-1.71.61.4
Distance moved, locomotor task time 23.84.56.3-2.1-2.0-2.02.0-2.12.1-2.52.52.1-2.0-1.8
Vertical activity count, locomotor time 23.33.64.3-1.6-1.7-1.91.9-2.12.1-1.91.92.0-2.0-2.0
Light reinforcement 11.62.93.92.01.91.8-1.81.8-1.81.7-1.7-1.41.41.2
Light reinforcement 20.20.20.30.30.40.5-0.50.5-0.50.3-0.3-0.50.60.5
Bone: marrow area1.94.15.4-1.5-1.6-2.12.1-2.22.2-1.81.82.2-2.3-2.3
Bone: maximum diameter3.56.47.8-2.2-2.4-2.72.7-2.82.8-2.22.22.6-2.6-2.7
Bone: maximum force0.40.71.1-0.6-0.9-1.01.0-1.01.0-0.20.20.8-0.8-1.1
Bone: maximum moment0.71.11.7-0.9-1.1-1.21.2-1.21.2-0.50.51.0-1.1-1.3
Mean time between licks in bursts6.08.511.3-2.5-2.3-2.72.7-2.82.8-3.43.43.2-3.2-3.0
Mean num. licks in bursts4.14.96.2-2.5-2.5-2.22.2-2.22.2-2.42.42.0-2.0-1.7
Cd content in liver0.20.20.60.70.60.4-0.30.3-0.30.5-0.5-0.10.10.0
Co content in liver1.51.82.6-1.1-1.0-1.11.1-1.21.2-1.61.61.6-1.5-1.3
Cu content in liver0.70.81.9-0.7-0.4-0.70.7-0.60.6-1.41.41.1-1.0-0.8
Fe content in liver0.00.00.10.20.10.1-0.10.3-0.30.2-0.2-0.00.00.0
K content in liver0.00.00.20.30.40.2-0.20.1-0.10.0-0.00.0-0.0-0.1
Mg content in liver0.20.30.3-0.5-0.4-0.50.5-0.60.6-0.60.60.4-0.4-0.4
Mn content in liver2.32.63.51.41.41.7-1.61.5-1.51.5-1.5-1.91.91.8
Na content in liver0.10.20.4-0.6-0.4-0.30.3-0.30.3-0.60.60.1-0.10.1
Rb content in liver1.41.72.0-1.2-1.3-1.31.3-1.31.3-1.21.21.4-1.4-1.4
Se content in liver5.66.98.12.62.82.8-2.82.6-2.62.3-2.3-2.62.62.6
Sr content in liver0.10.10.30.00.00.2-0.20.2-0.20.1-0.1-0.40.40.5
Zn content in liver5.86.47.6-2.7-2.6-2.62.6-2.52.5-2.82.82.4-2.3-2.1
Bone: minimum diameter1.12.04.3-0.6-0.8-1.41.4-1.41.4-1.01.01.8-1.8-2.1
Time in familiar zone, hab. session 10.00.00.10.30.30.1-0.10.1-0.10.1-0.10.1-0.1-0.1
Time in novel zone, hab. session 10.00.00.10.30.10.1-0.10.2-0.20.3-0.3-0.10.1-0.1
Total zone transitions, hab. session 10.00.10.1-0.4-0.4-0.10.1-0.10.10.1-0.1-0.20.30.3
Total locomotion distance, hab. session 10.20.30.90.90.90.5-0.50.6-0.60.4-0.4-0.10.0-0.0
Locomotion velocity, hab. session 10.10.10.40.60.60.3-0.30.3-0.30.2-0.20.0-0.0-0.1
Time in familiar zone, hab. session 22.32.42.9-1.3-1.5-1.61.6-1.71.7-1.31.31.6-1.7-1.7
Time in novel zone, hab. session 21.11.11.70.81.01.1-1.11.2-1.20.7-0.7-1.21.21.3
Total zone transitions, hab. session 20.71.02.1-1.4-1.2-1.01.0-1.01.0-1.11.10.5-0.4-0.1
Total locomotion distance, hab. session 20.10.10.40.10.2-0.20.2-0.20.2-0.50.50.6-0.6-0.6
Locomotion velocity, hab. session 20.10.10.30.20.4-0.10.1-0.00.0-0.40.40.5-0.5-0.5
Novel to familiar place preference ratio0.00.00.1-0.2-0.0-0.00.00.1-0.1-0.40.4-0.10.20.2
Novelty place preference0.10.10.1-0.10.10.1-0.10.3-0.3-0.40.4-0.20.30.3
Time in novel zone, NPP test0.10.10.3-0.3-0.1-0.10.10.0-0.0-0.50.5-0.00.10.2
Total zone transitions, NPP test0.00.10.3-0.3-0.10.1-0.10.1-0.1-0.10.1-0.30.40.5
Total locomotion distance, NPP test0.50.81.91.11.41.0-1.01.0-1.00.4-0.4-0.50.50.6
Locomotion velocity, NPP test1.01.43.01.41.71.3-1.31.4-1.40.7-0.7-0.90.90.9
Intraocular pressure0.20.20.6-0.8-0.8-0.50.5-0.50.5-0.30.30.0-0.00.1
Delta distance traveled before/after self-admin0.10.10.4-0.1-0.10.2-0.20.2-0.20.0-0.0-0.40.40.6
Delta ambulatory time before/after self-admin0.20.20.9-0.10.00.3-0.30.4-0.40.1-0.1-0.70.70.9
Parametrial fat weight0.10.30.80.90.70.2-0.20.2-0.20.7-0.70.2-0.3-0.6
Pavlov. Cond. lever latency1.41.82.41.31.31.3-1.31.3-1.31.5-1.5-1.41.41.2
Pavlov. Cond. magazine entry latency3.84.95.4-2.2-2.2-2.32.3-2.12.1-2.32.32.2-2.2-2.0
Pavlov. Cond. change in total contacts1.11.12.4-1.1-0.9-0.90.9-0.90.9-1.51.51.1-1.0-0.7
Pavlov. Cond. index score3.74.75.9-2.1-2.1-2.12.1-2.12.1-2.42.42.3-2.3-2.0
Pavlov. Cond. latency score3.64.65.7-2.1-2.1-2.12.1-2.02.0-2.42.42.2-2.2-1.9
Pavlov. Cond. lever contacts1.61.82.9-1.2-1.2-1.21.2-1.21.2-1.71.71.5-1.5-1.2
Pavlov. Cond. magazine entry number4.15.25.92.32.32.3-2.32.2-2.22.4-2.4-2.32.22.0
Pavlov. Cond. intertrial magazine entries2.53.13.91.81.92.0-2.01.8-1.81.4-1.4-1.81.81.7
Pavlov. Cond. lever-magazine prob. diff.3.03.74.6-1.8-1.8-1.91.9-1.81.8-2.12.12.0-2.0-1.8
Pavlov. Cond. response bias1.51.82.6-1.2-1.2-1.21.2-1.31.3-1.61.61.5-1.4-1.2
Pavlov. Cond. lever latency21.128.433.35.85.65.5-5.55.4-5.45.5-5.5-5.04.84.5
Pavlov. Cond. magazine entry latency5.36.18.2-2.8-2.9-2.72.7-2.72.7-2.22.22.1-2.0-1.9
Pavlov. Cond. change in total contacts13.819.024.1-4.9-4.6-4.44.4-4.44.4-4.74.73.9-3.8-3.4
Pavlov. Cond. index score16.721.425.8-5.1-4.9-4.84.8-4.84.8-4.74.74.2-4.1-3.8
Pavlov. Cond. latency score14.918.622.9-4.8-4.6-4.54.5-4.54.5-4.44.43.9-3.8-3.4
Pavlov. Cond. lever contacts22.330.435.6-6.0-5.8-5.75.7-5.75.7-5.65.65.1-5.0-4.7
Pavlov. Cond. magazine entry number7.59.112.53.53.43.1-3.13.2-3.23.2-3.2-2.52.42.1
Pavlov. Cond. intertrial magazine entries0.20.20.90.20.2-0.10.1-0.00.0-0.30.30.7-0.8-1.0
Pavlov. Cond. lever-magazine prob. diff.15.519.723.7-4.9-4.7-4.64.6-4.64.6-4.64.64.1-3.9-3.6
Pavlov. Cond. response bias22.630.836.3-6.0-5.9-5.85.8-5.75.7-5.65.65.1-5.0-4.7
Time in closed arm before self-admin0.30.31.1-1.1-1.1-0.40.4-0.40.4-0.60.6-0.10.20.4
Time in closed arm after self-admin1.01.11.50.80.71.0-1.01.0-1.01.0-1.0-1.21.21.2
Time in open arm before self-admin2.83.04.72.02.21.8-1.81.8-1.81.6-1.6-1.51.41.3
Time in open arm after self-admin1.11.22.4-0.6-0.7-1.11.1-1.11.1-0.80.81.4-1.4-1.6
Bone: periosteal estimation2.24.66.1-1.6-1.8-2.22.3-2.32.3-1.81.82.3-2.3-2.5
Bone: periosteal perimeter2.84.66.2-1.8-2.0-2.22.2-2.22.2-1.91.92.3-2.3-2.5
Bone: post-yield work0.81.11.6-0.9-1.2-1.21.2-1.31.3-0.50.51.0-1.1-1.2
Progressive ratio test 1 active lever presses0.50.50.60.70.70.7-0.70.7-0.70.8-0.8-0.70.70.6
Progressive ratio test 1 breakpoint0.40.40.50.60.70.6-0.60.6-0.60.7-0.7-0.60.60.4
Progressive ratio test 1 inactive lever presses0.10.10.2-0.3-0.3-0.40.4-0.30.3-0.20.20.3-0.3-0.4
Progressive ratio test 2 active lever presses1.31.41.6-1.1-1.2-1.21.2-1.31.3-1.11.11.1-1.1-1.2
Progressive ratio test 2 breakpoint1.31.51.7-1.2-1.2-1.21.2-1.31.3-1.11.11.2-1.2-1.3
Progressive ratio test 2 inactive lever presses0.50.50.9-0.8-0.9-0.80.8-0.80.8-0.60.60.6-0.7-0.7
Incentive Sensitization - Responses3.53.53.9-1.8-1.9-1.91.9-2.02.0-1.81.81.9-1.8-1.8
Incentive Sensitization - Breakpoint3.33.33.7-1.8-1.9-1.91.9-1.91.9-1.81.81.8-1.7-1.7
Sum of active levers in priming session hrs 5-60.00.00.10.10.20.2-0.20.2-0.2-0.20.2-0.20.20.4
Progressive ratio0.00.00.1-0.2-0.2-0.00.00.0-0.0-0.00.0-0.20.20.3
Food seeking constrained by brief footshock1.82.32.8-1.4-1.2-1.51.5-1.41.4-1.71.71.6-1.6-1.6
Seeking ratio, punishment vs. effort1.21.52.4-0.8-0.8-1.21.2-1.21.2-1.31.31.5-1.5-1.6
Retroperitoneal fat weight0.82.78.83.02.71.4-1.41.5-1.51.5-1.5-0.20.1-0.6
Reaction time number correct0.10.20.8-0.2-0.00.4-0.40.4-0.4-0.00.0-0.60.70.9
Reaction time mean minus median1.31.72.7-1.2-1.3-1.41.4-1.21.2-0.90.91.4-1.4-1.6
Reaction time mean minus median AUC1.21.62.1-1.4-1.5-1.31.3-1.21.2-1.01.01.3-1.3-1.3
Reaction time num false alarms1.31.83.01.71.71.4-1.41.3-1.31.3-1.3-1.11.00.8
Reaction time num false alarms AUC1.01.42.31.41.51.3-1.31.2-1.21.0-1.0-1.01.00.9
Reaction time trials correct on left0.10.20.8-0.2-0.00.4-0.40.4-0.4-0.00.0-0.60.70.9
Reaction time trials on left0.10.20.8-0.2-0.00.4-0.40.4-0.4-0.00.0-0.60.70.9
Reaction time mean0.20.30.90.80.60.4-0.40.5-0.51.0-1.0-0.20.2-0.2
Reaction time mean AUC0.70.91.81.21.00.9-0.90.9-0.91.3-1.3-0.70.60.3
Median of all reaction times0.81.12.01.31.20.9-0.91.0-1.01.4-1.4-0.80.70.4
Reaction time omissions0.10.10.10.40.30.2-0.20.3-0.30.3-0.3-0.10.1-0.2
Reaction time false alarm rate0.91.22.31.51.51.2-1.11.0-1.01.1-1.1-0.80.80.6
Reaction time premature initiation rate3.85.07.7-1.6-1.9-2.42.4-2.32.3-1.71.72.6-2.6-2.8
Reaction time premature initiations2.63.64.4-1.6-1.8-2.12.1-2.02.0-1.51.52.0-2.0-2.1
Std. dev. reaction times0.60.92.2-0.5-0.7-1.01.0-0.80.8-0.50.51.2-1.2-1.5
Reaction time trials completed0.10.20.8-0.2-0.00.4-0.40.4-0.4-0.00.0-0.60.70.9
Reaction time trials AUC0.10.10.5-0.2-0.10.3-0.30.4-0.4-0.10.1-0.50.50.7
Run reversals in cocaine runway, females0.80.72.80.40.2-0.60.6-0.60.6-0.30.31.2-1.4-1.7
Run reversals in cocaine runway, males0.00.00.10.20.10.1-0.10.1-0.10.3-0.3-0.10.1-0.0
Latency to leave start box in cocaine runway2.12.33.91.62.01.5-1.51.5-1.51.4-1.4-1.31.31.2
Latency to leave start box in cocaine runway, F1.11.22.81.31.71.2-1.21.1-1.10.8-0.8-0.70.70.7
Latency to leave start box in cocaine runway, M0.60.50.80.60.60.7-0.70.6-0.60.9-0.9-0.80.80.8
Std. dev. time between licks in bursts1.82.23.2-1.1-0.9-1.31.3-1.41.4-1.71.71.8-1.8-1.7
Total sessions with >9 infusions2.02.23.2-1.8-1.8-1.51.6-1.71.7-1.31.31.2-1.2-1.1
Short access day 1 total inactive lever presses0.40.40.50.70.60.7-0.70.7-0.70.6-0.6-0.60.60.5
Short access day 10 total inactive lever presses0.20.20.30.40.40.5-0.50.6-0.60.5-0.5-0.50.50.5
Short access day 1 total infusions2.22.42.6-1.6-1.6-1.51.5-1.61.6-1.51.51.5-1.5-1.5
Short access day 10 total infusions0.80.91.1-0.9-0.8-0.90.9-0.90.9-1.01.01.0-1.0-1.0
Short access total infusions0.80.91.2-0.9-0.9-1.01.0-1.01.0-0.90.91.0-1.0-1.1
Short access day 1 locomotion0.80.82.1-1.5-1.3-0.90.9-0.90.9-0.90.90.4-0.4-0.2
Short access day 10 total locomotion0.20.30.4-0.6-0.5-0.50.5-0.40.4-0.60.60.4-0.4-0.4
Short access total locomotion0.00.00.1-0.3-0.2-0.20.2-0.20.2-0.20.20.1-0.0-0.0
One hour access (0.3 mA shock)1.92.32.9-1.6-1.7-1.61.6-1.51.5-1.51.51.4-1.4-1.3
Compulsive drug intake0.10.10.3-0.2-0.10.1-0.10.1-0.1-0.10.1-0.30.30.5
One hour access (shock baseline)1.21.41.6-1.2-1.3-1.21.2-1.21.2-1.11.11.1-1.1-1.2
Social response proportion0.40.40.80.90.90.7-0.70.7-0.70.6-0.6-0.40.40.4
Social responses0.20.20.70.80.80.5-0.50.5-0.50.2-0.20.0-0.1-0.2
Social time4.66.07.42.32.52.5-2.52.7-2.72.0-2.0-2.52.52.6
Soleus weight0.30.82.70.20.0-0.70.7-0.70.7-0.40.41.3-1.4-1.6
Bone: stiffness0.10.10.40.20.1-0.30.3-0.30.30.4-0.40.3-0.3-0.6
Tibialis anterior weight0.30.91.4-0.6-0.7-1.01.0-0.90.9-0.70.71.1-1.1-1.2
Time to tail flick, vehicle, before self-admin0.00.00.10.2-0.1-0.10.1-0.20.20.3-0.30.0-0.1-0.1
Time to tail flick, vehicle, after self-admin1.61.72.7-1.6-1.6-1.31.3-1.31.3-1.31.31.1-1.1-1.0
Time to tail flick, test, before self-admin0.30.30.6-0.4-0.4-0.60.6-0.50.5-0.30.30.7-0.7-0.7
Time to tail flick, test, after self-admin0.30.30.6-0.3-0.1-0.40.4-0.30.3-0.70.70.8-0.7-0.7
Delta time to tail flick, vehicle, before/after SA1.11.12.3-1.5-1.2-1.01.0-1.01.0-1.21.20.8-0.7-0.4
Delta time to tail flick, test, before/after SA0.40.40.50.50.70.7-0.70.7-0.70.2-0.2-0.60.60.7
Tibia length0.92.75.1-2.3-2.1-1.71.7-1.71.7-1.71.71.0-0.9-0.6
Ambulatory time before self-admin0.90.91.01.00.90.9-0.91.0-1.01.0-1.0-1.01.00.9
Ambulatory time after self-admin2.93.24.61.31.41.8-1.81.9-1.91.7-1.7-2.12.12.1
Bone: tissue strength0.60.51.20.20.20.6-0.60.6-0.60.8-0.8-1.01.01.1
Total heroin consumption0.10.10.4-0.4-0.3-0.30.3-0.20.2-0.70.70.2-0.2-0.1
Bone: trabecular number0.60.92.31.10.60.8-0.70.6-0.61.5-1.5-1.00.90.6
Bone: trabecular spacing0.40.51.2-1.1-0.7-0.60.6-0.60.6-1.11.10.5-0.4-0.2
Bone: trabecular thickness0.10.10.20.40.10.0-0.00.1-0.10.3-0.30.2-0.2-0.4
Bone: trabecular tissue density0.50.71.81.21.30.8-0.81.0-1.00.7-0.7-0.30.2-0.0
Water consumed over 24 hours1.01.21.51.21.11.2-1.21.1-1.11.1-1.1-1.01.00.9
Number of responses in last shaping day0.60.61.0-0.5-0.6-0.80.8-0.70.7-0.80.81.0-1.0-1.0