Hub : Genes

Relt

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Relt 0.06 0.05 4.0e-05 0.03 0.03 0.03 0.03 2.5e-04 4.6e-04 1.2e-04 2.3e-04
2 pVTA isoform ratio XM_006229777.5 0.08 0.05 3.9e-05 0.05 0.05 0.04 0.05 5.2e-05 5.8e-05 5.0e-04 5.0e-05
3 pVTA intron excision ratio chr1_164626271_164636538 0.12 0.06 1.1e-08 0.09 0.1 0.09 0.09 1.3e-07 1.3e-08 2.0e-07 9.1e-08
4 Brain intron excision ratio chr1_164626271_164636538 0.13 0.07 8.1e-11 0.1 0.12 0.09 0.1 7.7e-10 7.3e-11 2.3e-08 1.0e-09
5 Brain mRNA stability Relt 0.09 0.05 4.0e-08 0.07 0.08 0.06 0.07 2.5e-07 6.0e-08 1.7e-06 9.7e-07
6 Adipose mRNA stability Relt 0.05 0.03 7.2e-05 0.01 0.03 0.03 0.03 7.8e-03 2.6e-04 2.4e-04 7.3e-04
7 NAcc intron excision ratio chr1_164626271_164636538 0.11 0.06 3.7e-10 0.06 0.07 0.06 0.06 3.9e-10 2.4e-10 3.2e-09 6.1e-10
8 Brain isoform ratio XM_006229777.5 0.1 0.06 3.7e-07 0.07 0.07 0.06 0.06 7.9e-07 4.6e-07 1.1e-06 1.9e-06
9 PL intron excision ratio chr1_164626271_164636538 0.05 0.03 3.6e-05 0.04 0.04 0.03 0.04 3.7e-05 4.5e-05 2.3e-04 8.1e-05
10 NAcc gene expression Relt 0.02 0.01 7.9e-03 0 0.01 0 0.01 5.3e-02 3.9e-03 5.2e-02 2.6e-02
11 IC intron excision ratio chr1_164626271_164636538 0.17 0.09 1.8e-04 0.08 0.09 0.09 0.09 2.2e-04 1.9e-04 1.5e-04 1.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.20.41.10.2-0.7-0.6-0.6-0.50.1-0.6-0.80.8-0.3-1.0
Area under the delay curve0.00.10.30.2-0.5-0.2-0.2-0.30.3-0.2-0.10.2-0.30.2
BMI with tail0.10.41.41.2-0.20.20.3-0.20.60.60.8-0.8-0.70.9
BMI without tail0.31.73.70.01.11.41.40.7-0.61.91.9-1.70.01.7
Body weight0.41.88.40.21.31.01.10.20.31.51.8-1.4-0.52.9
Weight adjusted by age0.10.20.6-0.10.80.50.50.2-0.10.70.7-0.2-0.00.5
Bone surface0.61.11.5-1.21.01.11.11.1-1.21.21.1-1.11.00.4
Bone volume0.20.40.7-0.90.60.70.70.7-0.70.60.6-0.60.60.4
Breakpoint value in progressive ratio session0.71.32.30.9-1.0-1.3-1.3-1.11.0-1.5-1.51.3-0.8-0.7
Number of licking bursts1.95.78.52.6-2.2-2.5-2.5-2.82.7-2.1-2.12.4-2.9-0.6
Context. condit. distance diff. score2.42.95.0-2.21.61.71.72.0-2.01.41.3-1.52.10.3
Locomotion velocity, session 10.50.62.20.4-1.0-0.7-0.7-0.40.0-0.7-0.90.8-0.1-1.5
Locomotion distance, session 10.81.02.0-1.30.80.90.91.1-1.40.80.6-0.81.3-0.4
Locomotion velocity, session 20.20.20.4-0.50.70.40.40.3-0.60.60.4-0.30.20.0
Locomotion distance, session 20.40.61.3-1.10.50.80.70.9-0.90.60.6-0.70.90.2
Locomotion velocity, session 30.50.61.3-1.00.90.70.71.0-1.00.50.4-0.51.1-0.1
Locomotion distance, session 30.91.02.2-1.30.60.90.81.2-1.50.70.4-0.61.4-0.8
Stereotopy head waving bouts, day 30.30.31.00.4-0.1-0.4-0.3-0.70.9-0.3-0.10.4-0.81.0
Stereotopy head waving duration, day 30.10.10.3-0.60.30.40.40.4-0.40.30.2-0.30.50.2
Locomotion velocity, session 70.30.30.50.1-0.6-0.6-0.6-0.50.2-0.6-0.70.7-0.3-0.7
Locomotion distance, session 70.20.30.60.3-0.7-0.6-0.6-0.50.7-0.6-0.50.4-0.50.1
Stereotopy head waving bouts, day 73.43.96.6-2.52.22.02.02.1-2.62.01.6-1.62.1-0.0
Stereotopy head waving duration, day 73.74.57.0-2.32.42.22.22.3-2.62.21.9-2.02.20.1
Locomotion velocity, session 81.01.32.4-1.51.31.11.11.2-1.21.00.9-0.91.20.6
Locomotion distance, session 82.63.86.1-2.51.92.02.02.2-2.11.71.7-1.82.20.8
Degree of sensitization distance0.80.94.00.7-0.2-0.4-0.3-0.91.4-0.30.20.1-1.22.0
Degree of sensitization stereotypy6.26.910.5-3.02.72.72.72.9-3.22.62.2-2.42.90.2
Conditioned locomotion0.30.41.00.2-0.3-0.5-0.5-0.21.0-1.0-0.60.50.10.9
Cocaine response after cond. corrected1.32.03.81.9-1.3-1.4-1.3-1.71.6-1.1-1.01.2-1.8-0.3
Cocaine response after cond. not corrected0.50.71.61.2-1.1-0.7-0.7-0.80.6-0.5-0.60.6-0.9-0.8
Cocaine response before conditioning1.72.04.4-1.40.81.41.31.7-2.11.20.9-1.21.9-1.1
Saline control response2.33.13.8-1.91.91.91.91.7-1.51.81.9-1.81.41.6
Bone: connectivity density0.30.53.90.1-0.7-0.2-0.3-0.0-0.7-0.1-0.50.40.1-2.0
Bone: cortical apparent density1.82.84.71.9-1.6-1.7-1.7-1.92.2-1.6-1.41.6-1.90.4
Bone: cortical area0.20.41.3-0.30.70.60.60.4-0.10.60.7-0.60.21.2
Bone: cortical porosity0.30.31.2-0.50.30.40.40.8-0.60.10.1-0.41.1-0.3
Bone: cortical porosity0.40.51.4-0.70.50.60.61.0-0.80.30.3-0.51.2-0.4
Bone: cortical thickness0.40.60.80.8-0.8-0.9-0.8-0.80.9-0.9-0.90.9-0.7-0.2
Bone: cortical thickness0.10.10.3-0.40.30.30.20.4-0.00.00.2-0.20.50.6
Bone: cortical tissue density1.82.94.71.9-1.6-1.7-1.7-1.92.2-1.7-1.41.6-1.90.3
Condit. Reinf. active minus inactive responses0.40.41.7-0.50.80.60.60.3-0.10.60.8-0.60.11.3
Condit. Reinf. active-inactive response ratio0.80.81.6-0.81.10.90.90.7-0.51.01.1-1.00.41.3
Condit. Reinf. active responses0.10.21.5-0.20.40.20.20.00.30.10.3-0.2-0.11.2
Condit. Reinf. inactive responses0.10.10.20.2-0.3-0.3-0.3-0.20.5-0.5-0.30.3-0.10.3
Incentive salience index mean0.40.51.5-0.60.90.60.70.4-0.20.70.8-0.70.31.2
Condit. Reinf. lever presses0.20.40.6-0.80.70.60.60.5-0.70.70.6-0.50.40.3
Condit. Reinf. active minus inactive responses7.611.615.2-3.63.93.63.63.3-3.23.63.6-3.52.82.5
Condit. Reinf. active-inactive response ratio1.32.12.8-1.51.51.61.61.5-1.71.71.5-1.51.30.5
Condit. Reinf. active responses11.716.822.6-4.34.84.34.33.9-3.54.34.4-4.33.33.4
Condit. Reinf. inactive responses6.08.912.8-3.13.63.13.12.7-2.23.03.3-3.12.33.1
Condit. Reinf. lever presses20.029.033.7-5.75.85.75.75.5-5.25.65.6-5.75.03.3
Condit. Reinf. lever reinforcers received13.719.225.8-4.65.14.64.64.2-3.94.64.7-4.63.63.4
Conditioned reinforcement - actives0.41.43.0-1.10.91.21.11.5-1.40.90.8-1.31.7-0.4
Conditioned reinforcement - inactives0.10.41.10.5-0.5-0.5-0.5-0.41.0-0.7-0.61.0-0.30.1
Conditioned locomotion1.62.35.3-1.91.21.41.32.0-2.01.00.8-1.22.3-1.0
Patch foraging indifference point 0 sec1.74.96.7-2.01.72.42.42.6-2.32.22.2-2.52.60.9
Patch foraging indifference point AUC0.20.41.2-0.41.00.40.50.00.10.60.7-0.5-0.31.1
Delay disc. indifference point, 0s delay1.41.51.8-1.31.31.31.31.2-1.01.21.3-1.31.11.3
Delay disc. indifference point, 16s delay0.20.31.00.5-1.0-0.5-0.5-0.30.7-0.7-0.50.3-0.20.2
Delay disc. indifference point, 2s delay1.11.32.1-1.01.41.11.10.8-1.01.21.2-1.40.51.1
Delay disc. indifference point, 24s delay1.21.93.11.6-1.8-1.4-1.4-1.31.6-1.6-1.31.2-1.10.1
Delay disc. indifference point, 4s delay1.51.63.6-1.01.61.31.30.9-0.61.41.6-1.20.51.9
Delay disc. indifference point, 8s delay0.00.10.30.0-0.6-0.2-0.2-0.20.3-0.2-0.10.4-0.2-0.1
Indifference point function ln k0.30.92.8-1.10.10.80.71.3-1.30.40.2-0.61.7-0.9
Indifference point function log k0.30.92.8-1.10.10.80.71.3-1.30.40.2-0.61.7-0.9
Patch foraging total patch changes 0 sec1.44.15.5-1.81.52.32.22.3-2.12.12.1-2.32.30.9
Patch foraging total patch changes 12 sec1.21.63.4-0.71.41.31.30.9-0.51.41.6-1.40.61.9
Patch foraging total patch changes 18 sec1.33.04.4-1.51.61.91.91.8-1.61.92.0-2.11.61.0
Patch foraging total patch changes 24 sec0.51.62.6-0.91.11.31.41.0-0.71.41.6-1.50.71.6
Patch foraging total patch changes 6 sec0.40.71.0-0.70.60.90.91.0-0.80.80.9-1.00.90.5
Patch foraging time to switch 0 sec1.55.96.92.5-2.4-2.6-2.6-2.52.4-2.6-2.52.6-2.3-1.5
Patch foraging water rate 0 sec1.24.55.8-2.11.72.32.32.4-2.22.12.1-2.32.40.9
Patch foraging water rate 12 sec0.62.64.4-1.61.01.71.62.0-1.91.41.4-1.72.10.0
Patch foraging water rate 18 sec1.12.53.1-1.71.51.71.71.6-1.71.81.7-1.61.40.9
Patch foraging water rate 24 sec0.60.82.6-0.90.20.90.81.3-1.10.40.4-0.81.6-0.5
Patch foraging water rate 6 sec0.91.42.3-1.40.71.21.21.4-1.41.00.9-1.11.5-0.2
Seeking ratio, delayed vs. immediate footshock1.31.93.81.7-1.5-1.4-1.4-1.20.7-1.3-1.51.1-1.0-2.0
Distance traveled before self-admin0.40.91.50.9-0.8-1.1-1.1-1.21.0-1.1-1.00.6-1.2-0.1
Distance traveled after self-admin0.40.71.70.2-0.5-0.9-1.0-0.50.1-1.2-1.30.7-0.1-1.3
Extensor digitorum longus weight0.10.41.51.2-0.5-0.2-0.2-0.70.70.20.3-0.1-1.10.6
Bone: elastic displacement2.43.04.11.4-1.8-1.9-1.9-1.71.2-1.7-2.02.0-1.4-1.9
Bone: elastic work3.03.97.41.9-2.3-2.0-2.0-1.71.1-1.8-2.22.1-1.4-2.7
Bone: endosteal estimation1.43.35.3-1.31.82.02.01.5-1.42.22.3-2.21.01.8
Bone: endosteal perimeter1.84.56.6-1.72.32.32.31.8-1.72.52.6-2.41.31.8
Epididymis fat weight0.31.42.31.5-1.3-1.2-1.1-1.31.4-1.0-0.91.0-1.3-0.3
Delta time in closed arm before/after self-admin1.71.63.61.9-1.3-1.1-1.1-1.51.6-0.8-0.60.5-1.80.5
Delta time in open arm before/after self-admin3.13.64.4-2.12.02.12.11.9-1.92.12.0-1.81.71.0
Diff in mean of infusions in LGA sessions2.54.56.31.8-1.4-2.4-2.3-2.52.3-2.3-2.22.5-2.4-0.4
Delay discount exponential model param0.10.10.2-0.30.50.20.20.3-0.30.20.1-0.10.4-0.1
Extinction: sum of active levers before priming0.10.10.3-0.10.50.30.30.1-0.10.30.3-0.20.00.5
Active lever presses in extinction session 61.11.13.6-1.70.30.60.61.4-1.4-0.0-0.1-0.51.9-1.0
Bone: final force0.20.30.80.6-0.4-0.4-0.5-0.40.9-0.7-0.40.4-0.30.8
Bone: final moment0.10.10.60.4-0.2-0.2-0.2-0.20.6-0.4-0.20.1-0.10.8
Food consumed during 24 hour testing period2.54.97.8-2.62.32.32.22.5-2.82.11.8-2.12.5-0.1
Glucose0.00.10.50.10.2-0.00.0-0.1-0.20.3-0.00.2-0.2-0.7
Heart weight0.81.21.7-1.21.31.21.21.3-1.11.01.0-1.01.30.5
Delay discount hyperbolic model param0.00.00.1-0.20.20.00.00.2-0.2-0.1-0.10.10.3-0.3
Intermittent access intake day 1-15 change0.20.82.1-1.10.80.80.80.9-1.50.80.5-0.80.9-0.7
Intermittent access intake escalation0.21.23.0-1.31.00.90.91.1-1.71.00.7-0.91.1-0.9
Intermittent access intake escalation 20.40.71.2-0.70.60.80.80.9-1.10.90.7-1.00.8-0.3
Intermitt. access day 1 inactive lever presses0.11.73.21.5-1.3-1.3-1.2-1.41.8-1.2-1.01.6-1.40.0
Intermitt. access day 15 inactive lever presses0.20.92.60.0-0.4-1.0-1.0-0.80.9-1.2-1.21.6-0.5-0.4
Intermitt. access escalation Index0.00.00.0-0.10.00.20.20.1-0.10.20.2-0.10.10.0
Intermittent access day 1 total infusions0.72.24.0-2.01.61.51.51.7-1.41.21.2-1.11.80.4
Intermittent access day 15 total infusions0.92.24.4-2.11.51.51.51.8-1.71.31.2-1.11.90.0
Intermittent access terminal intake (last 3 days)1.52.74.5-2.11.81.71.71.9-1.61.51.4-1.32.00.4
Intermittent access total infusions2.42.84.4-2.11.81.81.81.9-1.61.61.6-1.31.90.6
Intermittent access day 1 locomotion0.20.41.3-1.10.60.50.50.7-0.60.30.20.00.9-0.2
Intermittent access day 15 total locomotion0.31.12.2-1.50.60.90.91.3-1.50.70.5-0.41.5-1.1
Intermittent access total locomotion1.01.23.1-1.81.21.11.11.3-1.20.90.8-0.61.4-0.0
Intermittent access standard deviation0.00.20.5-0.20.50.30.40.1-0.20.50.5-0.6-0.00.7
Left kidney weight0.10.82.50.20.70.80.90.3-0.01.11.3-1.1-0.21.6
Right kidney weight0.21.44.60.10.81.11.20.5-0.11.41.8-1.6-0.12.1
Cocaine induced anxiety1.13.13.71.9-1.9-1.9-1.9-1.81.8-1.9-1.81.7-1.6-0.8
Post-drug Anxiety2.12.43.21.5-1.4-1.7-1.7-1.81.8-1.7-1.51.7-1.70.0
Baseline Anxiety0.50.81.6-1.11.20.91.00.7-0.61.01.0-0.50.51.3
Tail length0.95.114.2-1.62.92.12.21.1-1.02.72.8-2.00.23.8
Length with tail0.94.214.9-1.62.71.81.91.0-0.52.12.4-1.70.23.9
Length without tail0.00.20.9-0.40.5-0.2-0.1-0.30.5-0.1-0.00.4-0.51.0
Times rat made contact with spout0.10.20.80.40.0-0.3-0.2-0.60.40.10.00.3-0.90.4
Lifetime Intake2.83.45.4-2.32.02.02.02.1-1.81.81.7-1.52.10.6
Liver weight, left0.20.30.80.9-0.3-0.0-0.0-0.40.60.20.4-0.3-0.80.9
Liver weight, right0.81.33.21.8-0.8-0.7-0.7-1.31.7-0.4-0.10.3-1.71.5
Locomotor activity0.30.50.9-0.80.50.80.70.9-0.60.50.6-0.71.00.6
Locomotor testing distance1.12.73.3-1.71.51.81.81.6-1.41.71.8-1.81.41.5
Locomotor testing rearing0.31.33.3-1.01.41.11.20.7-0.51.21.4-1.10.41.8
Locomotion in novel chamber0.20.31.80.0-0.40.1-0.00.6-0.4-0.3-0.2-0.50.9-1.4
Locomotion in novel chamber post-restriction0.92.75.0-1.91.41.71.61.9-2.21.61.3-1.61.9-0.6
Fecal boli incidents, locomotor time 10.10.41.7-0.1-0.40.20.10.7-0.4-0.2-0.1-0.41.1-1.3
Change in fecal boli incidents, locomotor task0.30.40.80.6-0.9-0.6-0.6-0.80.4-0.4-0.50.2-0.90.2
Time >=10cm from walls, locomotor time 11.01.33.1-1.30.91.21.21.6-0.90.80.9-0.81.80.3
Bouts of movement, locomotor time 10.20.20.6-0.80.60.40.40.5-0.30.20.3-0.50.50.4
Total resting periods, locomotor time 10.10.10.5-0.70.20.10.10.4-0.4-0.2-0.1-0.30.6-0.2
Rest time, locomotor task time 10.10.20.5-0.4-0.2-0.3-0.4-0.0-0.2-0.5-0.60.20.3-0.7
Distance moved, locomotor task time 10.10.20.40.50.30.30.4-0.00.40.60.60.2-0.40.5
Vertical activity count, locomotor time 10.00.31.0-0.20.50.60.70.40.00.70.9-0.40.21.0
Time >=10cm from walls, locomotor time 20.82.34.4-1.51.61.61.61.6-0.61.31.6-1.01.52.1
Bouts of movement, locomotor time 20.20.84.20.20.50.70.70.40.30.61.0-1.20.12.0
Total resting periods, locomotor time 20.10.42.60.50.10.30.30.00.50.20.6-0.9-0.21.6
Rest time, locomotor task time 21.93.24.11.6-1.8-2.0-2.0-2.01.5-2.0-1.91.6-1.8-1.2
Distance moved, locomotor task time 22.63.44.6-1.62.12.12.12.0-1.22.12.1-1.21.71.6
Vertical activity count, locomotor time 20.51.32.5-0.81.11.21.21.1-0.41.21.4-1.00.91.6
Light reinforcement 11.14.87.62.8-2.4-2.2-2.2-2.32.1-2.0-2.02.1-2.3-1.2
Light reinforcement 20.20.52.50.6-0.9-0.6-0.6-0.5-0.2-0.4-0.80.7-0.4-1.6
Bone: marrow area1.12.74.6-1.11.61.81.81.3-1.22.12.1-2.00.81.7
Bone: maximum diameter1.73.44.7-1.52.22.02.01.6-1.42.12.2-2.01.31.8
Bone: maximum force0.00.10.20.4-0.3-0.2-0.2-0.20.4-0.3-0.20.2-0.10.3
Bone: maximum moment0.00.00.10.1-0.10.00.00.00.1-0.00.0-0.10.00.3
Mean time between licks in bursts1.26.914.2-1.83.02.72.82.2-1.32.73.1-3.01.63.8
Mean num. licks in bursts1.95.16.7-2.52.22.42.32.6-2.52.12.0-2.32.60.7
Cd content in liver0.20.20.70.60.1-0.3-0.3-0.60.5-0.0-0.00.3-0.80.5
Co content in liver1.61.93.3-1.21.51.41.51.2-0.81.41.6-1.51.01.8
Cu content in liver0.81.02.4-0.31.21.01.00.5-0.41.31.4-1.10.01.6
Fe content in liver0.00.00.00.1-0.0-0.1-0.1-0.10.1-0.1-0.10.2-0.10.1
K content in liver0.20.20.90.40.2-0.2-0.2-0.40.6-0.10.00.1-0.51.0
Mg content in liver0.10.10.2-0.20.50.40.40.3-0.30.40.4-0.40.30.3
Mn content in liver1.61.83.11.0-1.6-1.4-1.4-1.00.7-1.4-1.61.4-0.7-1.8
Na content in liver0.91.11.9-1.31.41.01.00.9-1.41.10.9-0.80.80.0
Rb content in liver0.50.50.8-0.80.90.80.80.7-0.90.80.7-0.70.60.2
Se content in liver5.26.27.62.4-2.5-2.7-2.7-2.52.2-2.6-2.72.8-2.2-1.9
Sr content in liver0.20.21.2-0.40.10.20.20.3-0.70.3-0.0-0.10.4-1.1
Zn content in liver3.03.44.7-1.62.02.02.01.8-1.62.12.1-2.21.61.2
Bone: minimum diameter0.81.66.1-0.41.51.11.20.5-0.11.41.6-1.2-0.12.5
Time in familiar zone, hab. session 10.10.10.2-0.10.40.20.2-0.0-0.00.40.3-0.2-0.20.4
Time in novel zone, hab. session 10.30.40.50.7-0.6-0.7-0.7-0.60.7-0.7-0.60.6-0.6-0.2
Total zone transitions, hab. session 10.10.20.6-0.80.40.10.10.2-0.70.1-0.20.30.4-0.8
Total locomotion distance, hab. session 10.60.92.61.0-0.2-0.6-0.5-1.11.4-0.4-0.10.4-1.41.6
Locomotion velocity, hab. session 10.40.62.60.7-0.1-0.4-0.4-0.81.2-0.30.00.3-1.01.6
Time in familiar zone, hab. session 21.82.02.7-1.41.21.51.51.5-1.11.31.5-1.61.31.6
Time in novel zone, hab. session 20.70.72.00.8-0.7-0.8-0.9-0.70.4-0.8-1.00.9-0.6-1.4
Total zone transitions, hab. session 21.62.14.3-2.11.81.41.41.6-1.81.21.0-0.91.60.2
Total locomotion distance, hab. session 20.70.96.9-0.21.10.40.5-0.00.70.40.8-0.5-0.32.6
Locomotion velocity, hab. session 20.71.07.6-0.11.00.30.4-0.20.80.40.8-0.4-0.52.8
Novel to familiar place preference ratio0.20.32.0-0.40.70.20.20.30.4-0.10.2-0.20.41.4
Novelty place preference0.30.32.2-0.40.80.30.30.30.4-0.10.2-0.20.41.5
Time in novel zone, NPP test0.40.52.6-0.60.90.40.40.50.20.00.4-0.40.61.6
Total zone transitions, NPP test0.20.30.9-0.90.60.40.40.5-0.90.30.1-0.10.6-0.7
Total locomotion distance, NPP test0.40.61.80.8-0.2-0.4-0.4-0.81.2-0.30.00.2-1.11.4
Locomotion velocity, NPP test0.60.92.01.2-0.5-0.7-0.7-1.11.4-0.5-0.30.6-1.41.1
Intraocular pressure0.40.75.70.2-0.5-0.0-0.10.2-0.90.1-0.30.00.4-2.4
Delta distance traveled before/after self-admin1.41.63.2-1.51.31.21.21.6-1.60.90.8-0.91.8-0.2
Delta ambulatory time before/after self-admin0.81.43.2-1.51.11.11.11.5-1.60.80.7-0.81.8-0.5
Parametrial fat weight0.71.63.01.7-1.3-1.2-1.2-1.40.7-0.7-1.01.0-1.5-1.6
Pavlov. Cond. lever latency1.72.12.61.6-1.5-1.5-1.5-1.51.4-1.5-1.51.5-1.4-0.8
Pavlov. Cond. magazine entry latency4.15.26.8-2.62.22.42.42.3-2.32.42.4-2.42.11.3
Pavlov. Cond. change in total contacts1.82.02.7-1.61.31.51.51.4-1.41.51.5-1.51.30.8
Pavlov. Cond. index score3.44.45.3-2.32.12.22.22.1-2.22.32.2-2.21.91.1
Pavlov. Cond. latency score3.24.15.1-2.32.02.22.22.1-2.12.12.1-2.11.91.1
Pavlov. Cond. lever contacts1.61.92.4-1.41.41.51.51.4-1.41.51.5-1.51.20.6
Pavlov. Cond. magazine entry number4.25.36.72.6-2.3-2.5-2.5-2.42.4-2.5-2.42.4-2.1-1.2
Pavlov. Cond. intertrial magazine entries0.91.11.61.0-0.9-1.1-1.1-1.11.1-1.2-1.21.3-1.0-0.4
Pavlov. Cond. lever-magazine prob. diff.2.93.64.6-2.11.92.02.01.9-2.12.12.0-2.01.70.8
Pavlov. Cond. response bias2.02.53.2-1.81.51.71.71.6-1.71.71.6-1.61.40.7
Pavlov. Cond. lever latency21.229.733.85.7-5.8-5.8-5.8-5.75.5-5.6-5.55.7-5.3-2.9
Pavlov. Cond. magazine entry latency4.05.77.5-2.72.32.52.52.7-2.72.32.2-2.42.60.5
Pavlov. Cond. change in total contacts9.824.030.7-5.45.55.15.25.0-5.05.04.8-4.94.62.6
Pavlov. Cond. index score13.921.824.7-5.05.05.05.04.9-4.84.84.7-4.94.62.4
Pavlov. Cond. latency score11.818.921.4-4.64.64.64.64.6-4.54.44.3-4.54.32.0
Pavlov. Cond. lever contacts19.428.634.0-5.65.85.75.75.5-5.35.55.4-5.65.12.9
Pavlov. Cond. magazine entry number8.010.413.83.7-3.2-3.4-3.4-3.53.6-3.2-3.03.2-3.4-0.9
Pavlov. Cond. intertrial magazine entries0.20.52.10.20.80.50.50.00.20.70.9-0.6-0.41.4
Pavlov. Cond. lever-magazine prob. diff.13.320.423.2-4.84.84.84.84.7-4.64.64.6-4.74.42.4
Pavlov. Cond. response bias21.029.134.0-5.85.85.75.75.6-5.55.55.4-5.65.22.7
Time in closed arm before self-admin1.11.95.1-2.21.31.21.21.7-1.60.80.7-0.82.00.3
Time in closed arm after self-admin1.01.12.10.8-1.4-1.2-1.2-0.90.9-1.4-1.30.9-0.6-0.5
Time in open arm before self-admin4.55.510.63.3-2.6-2.4-2.4-2.52.1-2.0-2.11.8-2.5-1.9
Time in open arm after self-admin0.20.20.60.20.40.50.50.1-0.30.80.7-0.6-0.20.1
Bone: periosteal estimation1.02.33.7-0.91.51.61.71.2-1.11.91.9-1.80.81.6
Bone: periosteal perimeter1.22.43.7-1.11.61.71.71.3-1.21.91.9-1.80.91.5
Bone: post-yield work0.00.10.2-0.20.20.20.20.2-0.10.20.3-0.30.20.4
Progressive ratio test 1 active lever presses0.10.10.6-0.80.30.00.00.2-0.4-0.0-0.20.30.4-0.6
Progressive ratio test 1 breakpoint0.10.10.5-0.70.30.00.00.2-0.4-0.0-0.20.30.3-0.6
Progressive ratio test 1 inactive lever presses0.00.10.4-0.2-0.2-0.1-0.10.10.2-0.3-0.30.70.3-0.5
Progressive ratio test 2 active lever presses0.50.71.1-1.01.01.01.00.9-0.81.00.9-0.50.80.2
Progressive ratio test 2 breakpoint0.60.81.1-1.11.01.01.00.9-0.91.10.9-0.50.80.1
Progressive ratio test 2 inactive lever presses0.10.31.1-1.10.50.50.50.8-0.40.30.30.30.9-0.2
Incentive Sensitization - Responses0.41.11.5-0.91.21.21.21.1-0.71.21.2-0.70.90.7
Incentive Sensitization - Breakpoint0.41.01.3-0.91.11.11.11.0-0.81.21.1-0.70.90.5
Sum of active levers in priming session hrs 5-60.10.10.6-0.60.5-0.1-0.1-0.00.3-0.3-0.30.80.10.3
Progressive ratio0.20.51.3-1.10.10.60.60.8-1.10.70.4-0.20.8-0.8
Food seeking constrained by brief footshock1.62.02.7-1.31.51.51.51.1-1.11.61.6-1.60.81.6
Seeking ratio, punishment vs. effort0.51.14.4-0.21.40.90.90.4-0.11.01.3-1.30.02.1
Retroperitoneal fat weight1.35.614.43.0-1.9-2.1-2.0-3.13.1-1.3-1.01.7-3.81.4
Reaction time number correct0.00.20.5-0.3-0.4-0.1-0.20.3-0.1-0.6-0.50.30.7-0.5
Reaction time mean minus median0.21.11.7-0.91.11.11.11.0-0.61.01.2-1.20.81.3
Reaction time mean minus median AUC0.21.31.8-1.21.21.21.21.3-0.90.91.1-1.31.31.0
Reaction time num false alarms1.83.05.32.1-1.7-1.7-1.7-1.92.3-1.7-1.31.5-2.00.3
Reaction time num false alarms AUC0.81.93.31.7-1.5-1.4-1.4-1.41.8-1.4-1.11.1-1.40.1
Reaction time trials correct on left0.00.20.5-0.3-0.4-0.1-0.20.3-0.1-0.6-0.50.30.7-0.5
Reaction time trials on left0.10.20.5-0.3-0.4-0.1-0.20.3-0.1-0.6-0.60.30.7-0.6
Reaction time mean0.51.12.81.1-0.8-1.0-0.9-1.11.7-1.0-0.60.8-1.21.0
Reaction time mean AUC0.61.32.81.2-0.9-1.2-1.1-1.31.7-1.2-0.91.0-1.30.6
Median of all reaction times1.32.14.21.5-1.3-1.4-1.4-1.62.1-1.5-1.11.3-1.60.6
Reaction time omissions0.10.10.40.3-0.1-0.2-0.2-0.40.6-0.10.10.1-0.50.6
Reaction time false alarm rate1.41.93.41.8-1.3-1.3-1.3-1.61.8-1.1-0.91.0-1.70.3
Reaction time premature initiation rate1.62.44.4-0.91.51.61.71.1-0.92.02.1-1.90.61.9
Reaction time premature initiations0.61.72.6-1.01.11.51.51.2-1.01.51.6-1.61.01.3
Std. dev. reaction times0.20.63.2-0.10.70.60.60.20.30.61.0-0.8-0.11.8
Reaction time trials completed0.10.20.5-0.3-0.4-0.1-0.20.3-0.1-0.6-0.60.30.7-0.6
Reaction time trials AUC0.00.10.4-0.3-0.4-0.1-0.20.3-0.0-0.5-0.50.30.6-0.3
Run reversals in cocaine runway, females0.60.62.90.40.50.10.2-0.70.70.70.8-0.0-1.21.7
Run reversals in cocaine runway, males0.20.20.7-0.0-0.8-0.4-0.4-0.30.0-0.3-0.40.6-0.2-0.9
Latency to leave start box in cocaine runway2.23.05.82.2-1.7-1.7-1.7-2.21.8-1.3-1.31.5-2.4-0.4
Latency to leave start box in cocaine runway, F2.12.65.92.2-1.3-1.5-1.4-2.11.9-1.0-0.91.3-2.40.4
Latency to leave start box in cocaine runway, M0.60.51.50.6-0.8-0.7-0.7-0.60.3-0.6-0.70.8-0.5-1.2
Std. dev. time between licks in bursts1.12.07.3-0.41.31.41.40.8-0.11.41.9-1.70.42.7
Total sessions with >9 infusions3.44.25.4-2.32.12.22.12.2-2.22.12.0-2.12.10.6
Short access day 1 total inactive lever presses0.10.10.2-0.50.30.40.40.4-0.20.30.4-0.20.40.4
Short access day 10 total inactive lever presses0.21.21.91.0-1.2-1.1-1.1-1.01.4-1.2-1.11.4-0.9-0.3
Short access day 1 total infusions2.95.76.9-2.52.42.62.62.5-2.12.42.5-2.62.31.5
Short access day 10 total infusions2.03.35.2-2.32.21.91.91.9-1.81.91.8-1.51.70.6
Short access total infusions2.94.15.9-2.42.12.22.22.3-2.02.02.0-1.72.20.6
Short access day 1 locomotion1.62.74.7-1.81.01.71.62.0-2.21.51.3-1.52.1-0.8
Short access day 10 total locomotion0.52.02.9-1.71.61.51.51.4-1.51.41.4-1.21.30.6
Short access total locomotion0.50.81.6-1.20.70.80.81.0-1.30.80.5-0.51.1-0.7
One hour access (0.3 mA shock)1.31.62.3-1.51.31.41.31.5-1.21.21.2-1.01.50.1
Compulsive drug intake1.42.04.41.2-1.9-1.4-1.5-0.90.6-1.6-1.81.3-0.5-2.1
One hour access (shock baseline)1.43.75.0-2.22.22.02.02.1-1.71.91.9-1.72.01.0
Social response proportion0.40.61.81.3-0.7-0.5-0.5-0.71.2-0.6-0.30.3-0.80.6
Social responses0.50.73.10.9-0.2-0.3-0.3-0.61.4-0.30.20.0-0.91.8
Social time2.23.54.61.8-1.8-2.0-2.0-1.91.9-2.1-2.12.2-1.6-0.7
Soleus weight0.31.03.11.5-0.5-0.2-0.1-0.91.30.20.6-0.2-1.41.8
Bone: stiffness0.50.92.21.0-0.7-0.8-0.8-1.01.5-0.9-0.60.7-1.01.0
Tibialis anterior weight0.10.32.00.20.30.40.40.10.30.50.7-0.6-0.21.4
Time to tail flick, vehicle, before self-admin0.30.41.2-1.01.10.60.70.6-0.60.60.50.10.60.2
Time to tail flick, vehicle, after self-admin1.02.03.3-1.21.11.41.41.6-1.71.41.2-1.81.60.1
Time to tail flick, test, before self-admin1.21.43.5-1.31.91.21.20.8-0.71.41.3-0.50.41.2
Time to tail flick, test, after self-admin0.70.83.5-0.50.90.80.90.50.20.91.1-0.50.11.9
Delta time to tail flick, vehicle, before/after SA0.60.62.0-0.30.10.70.70.9-1.00.70.7-1.40.9-0.4
Delta time to tail flick, test, before/after SA0.60.81.61.2-1.3-0.8-0.9-0.81.1-1.0-0.80.6-0.6-0.1
Tibia length1.44.07.5-2.72.12.01.92.4-2.31.41.4-1.72.70.4
Ambulatory time before self-admin0.41.21.80.9-1.0-1.3-1.3-1.20.9-1.3-1.30.8-1.1-0.5
Ambulatory time after self-admin0.20.41.3-0.6-0.2-0.4-0.40.1-0.5-0.8-1.00.20.6-1.1
Bone: tissue strength1.01.04.10.4-1.0-0.9-1.0-0.50.1-1.0-1.31.1-0.1-2.0
Total heroin consumption0.10.10.5-0.70.40.10.20.2-0.0-0.10.00.10.30.6
Bone: trabecular number1.01.83.21.0-1.3-1.4-1.4-1.30.7-1.3-1.61.6-1.1-1.8
Bone: trabecular spacing0.81.21.6-1.21.01.11.11.3-1.31.01.0-1.11.3-0.0
Bone: trabecular thickness0.50.71.30.6-0.5-0.8-0.7-0.91.2-0.8-0.60.8-0.90.9
Bone: trabecular tissue density1.32.46.11.7-0.6-1.3-1.2-1.72.5-1.3-0.71.1-1.91.9
Water consumed over 24 hours0.20.40.60.5-0.5-0.7-0.7-0.70.4-0.6-0.70.8-0.6-0.7
Number of responses in last shaping day0.30.30.90.6-0.5-0.4-0.4-0.70.9-0.3-0.10.3-0.80.6