Hub : Genes

Pak1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr1_161562933_161585186 0.04 0.03 9.5e-04 0.02 0.02 0.02 0.01 2.6e-03 3.1e-03 3.7e-03 7.0e-03
2 Liver gene expression Pak1 0.09 0.05 3.3e-08 0.05 0.06 0.05 0.05 4.1e-06 4.0e-07 2.0e-06 2.9e-06
3 Adipose gene expression Pak1 0.03 0.02 8.6e-03 0 -0 -0 0.01 1.1e-01 4.2e-01 4.4e-01 1.1e-02
4 NAcc alternative polyA XM_063287516.1 0.01 0.01 7.9e-03 0.01 0.01 0.01 0.01 3.0e-03 6.6e-03 1.8e-02 1.1e-02
5 Liver alternative polyA XM_063287516.1 0.03 0.02 9.2e-03 0.01 0 -0 0.01 1.4e-02 1.1e-01 6.6e-01 4.9e-02
6 Brain isoform ratio NM_017198.2 0.05 0.04 6.2e-03 0.03 0.03 0.02 0.02 1.4e-03 1.7e-03 2.7e-03 2.7e-03
7 Liver isoform ratio XM_063287520.1 0.06 0.06 1.1e-03 0.03 0.01 0.01 0.02 2.9e-04 1.2e-02 7.7e-03 1.3e-03
8 LHb gene expression Pak1 0.2 0.13 7.6e-03 0.14 0.07 0.13 0.13 2.8e-04 1.2e-02 6.0e-04 4.5e-04
9 Brain mRNA stability Pak1 0.05 0.03 1.1e-03 0.03 0.03 0.03 0.03 1.0e-03 3.6e-04 9.3e-04 1.2e-03
10 Brain gene expression Pak1 0.21 0.1 0.0e+00 0.13 0.19 0.19 0.18 5.1e-12 1.7e-17 3.3e-17 2.2e-16
11 pVTA gene expression Pak1 0.07 0.05 2.3e-05 0.06 0.06 0.04 0.05 2.9e-05 2.3e-05 2.1e-04 8.0e-05
12 IC gene expression Pak1 0.27 0.12 1.5e-07 0.16 0.14 0.13 0.14 3.5e-07 1.2e-06 5.5e-06 1.2e-06
13 NAcc gene expression Pak1 0.09 0.05 2.1e-13 0.1 0.09 0.09 0.09 2.8e-14 1.7e-13 6.6e-14 7.0e-14
14 PL gene expression Pak1 0.87 0 0.0e+00 0.19 0.15 0.16 0.16 3.4e-20 1.6e-16 5.8e-17 2.3e-17
15 OFC gene expression Pak1 0.41 0.16 2.0e-07 0.26 0.24 0.24 0.26 6.2e-07 1.8e-06 1.6e-06 7.2e-07
16 BLA gene expression Pak1 0.1 0.06 7.5e-04 0.04 0.03 0.02 0.02 3.9e-03 9.1e-03 3.3e-02 1.9e-02
17 IL gene expression Pak1 0.49 0.16 2.2e-08 0.24 0.24 0.29 0.24 1.8e-06 2.1e-06 9.8e-08 2.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.20.30.6-0.7-0.4-0.2-0.10.30.4-0.60.60.40.50.50.50.50.50.80.70.5
Area under the delay curve0.40.51.70.10.8-1.3-1.3-0.5-1.01.1-0.51.0-0.10.50.20.30.30.20.10.1
BMI with tail1.86.312.60.0-0.33.43.52.30.7-0.4-0.4-3.5-2.2-3.4-3.1-2.9-2.9-2.7-2.8-2.3
BMI without tail2.88.517.20.60.03.83.92.40.4-0.1-0.7-4.1-2.8-4.0-3.7-3.5-3.5-3.3-3.4-2.9
Body weight2.310.322.50.4-0.34.44.52.41.2-0.2-0.4-4.7-2.9-4.4-4.0-3.8-3.8-3.3-3.3-2.9
Weight adjusted by age0.61.02.20.90.70.40.60.7-0.30.8-0.6-0.9-1.3-1.3-1.4-1.2-1.2-1.0-1.0-1.5
Bone surface0.61.03.01.31.7-1.2-1.1-0.9-1.61.3-1.30.7-1.1-0.2-0.6-0.6-0.6-0.2-0.3-0.8
Bone volume0.30.61.50.91.2-0.6-0.5-0.0-1.11.0-1.00.2-1.1-0.5-0.8-0.8-0.8-0.4-0.4-1.0
Breakpoint value in progressive ratio session0.70.91.6-1.2-0.8-0.1-0.10.20.8-0.91.20.71.11.01.01.11.11.21.01.2
Number of licking bursts1.21.95.2-2.3-2.01.82.02.11.8-2.11.4-1.10.8-0.20.10.10.10.20.10.5
Context. condit. distance diff. score1.51.85.01.21.9-2.2-1.8-1.4-2.02.0-1.51.8-0.60.70.20.30.30.40.6-0.2
Locomotion velocity, session 10.91.02.4-0.00.2-1.4-1.5-0.6-0.60.50.01.50.81.41.21.21.20.91.00.8
Locomotion distance, session 10.30.41.40.60.6-1.0-0.7-1.2-1.00.7-0.80.80.10.50.50.50.5-0.0-0.00.4
Locomotion velocity, session 20.30.41.20.91.0-0.7-1.1-0.4-0.90.6-0.70.4-0.5-0.1-0.3-0.3-0.3-0.3-0.3-0.6
Locomotion distance, session 20.10.10.50.70.20.1-0.1-0.6-0.10.4-0.1-0.3-0.2-0.3-0.2-0.2-0.2-0.3-0.3-0.1
Locomotion velocity, session 30.20.20.60.50.6-0.7-0.8-0.5-0.50.7-0.30.5-0.10.20.10.10.10.20.1-0.1
Locomotion distance, session 31.11.23.40.61.2-1.8-1.6-1.2-1.41.2-0.91.80.11.10.80.80.80.70.70.4
Stereotopy head waving bouts, day 31.41.65.6-0.7-1.72.01.60.92.4-1.52.0-1.80.6-0.7-0.2-0.2-0.20.1-0.10.2
Stereotopy head waving duration, day 30.20.20.80.3-0.40.40.1-0.60.8-0.50.9-0.40.40.00.30.30.30.40.20.3
Locomotion velocity, session 70.20.30.9-0.30.3-0.9-0.90.4-0.50.7-0.10.80.00.50.30.30.30.40.7-0.2
Locomotion distance, session 70.40.51.40.01.0-0.9-0.50.4-1.21.1-1.10.6-0.8-0.1-0.5-0.5-0.5-0.3-0.1-0.7
Stereotopy head waving bouts, day 70.60.72.60.90.3-0.8-1.2-1.60.10.40.50.80.60.80.80.90.90.91.00.7
Stereotopy head waving duration, day 70.40.42.71.50.8-0.6-0.9-1.6-0.40.7-0.10.3-0.10.10.10.10.10.20.2-0.0
Locomotion velocity, session 83.03.611.71.32.5-3.4-3.2-1.5-2.62.7-1.62.8-0.61.30.60.60.61.01.0-0.3
Locomotion distance, session 80.91.33.31.51.6-1.7-1.5-1.5-1.61.8-1.21.2-0.60.40.00.10.10.10.3-0.3
Degree of sensitization distance1.51.62.80.10.01.21.31.2-0.0-0.0-0.6-1.6-1.3-1.7-1.6-1.6-1.6-1.6-1.4-1.3
Degree of sensitization stereotypy1.51.66.01.61.4-1.8-2.0-2.5-1.21.1-0.61.50.11.00.80.80.80.80.90.5
Conditioned locomotion0.30.30.6-0.2-0.3-0.4-0.6-0.10.30.30.50.60.70.70.70.80.80.60.60.6
Cocaine response after cond. corrected0.20.21.1-0.70.2-0.0-0.11.0-0.50.2-0.70.2-0.4-0.2-0.3-0.3-0.3-0.5-0.6-0.5
Cocaine response after cond. not corrected0.10.10.3-0.50.2-0.4-0.40.1-0.40.1-0.40.5-0.00.30.20.20.20.00.00.1
Cocaine response before conditioning0.81.02.90.3-0.5-0.4-0.4-1.70.7-0.61.00.41.10.91.11.11.11.21.41.3
Saline control response0.60.82.41.61.00.10.3-1.2-1.00.2-1.1-0.6-1.0-0.9-0.8-0.9-0.9-1.1-0.9-0.6
Bone: connectivity density0.50.81.6-0.20.2-1.2-1.2-0.7-0.20.10.31.30.71.21.01.01.01.21.00.8
Bone: cortical apparent density0.30.41.4-1.1-0.80.50.71.10.6-1.20.5-0.10.40.20.10.20.20.10.10.3
Bone: cortical area0.71.12.30.50.90.20.70.4-0.90.2-1.2-0.7-1.5-1.2-1.4-1.4-1.4-1.1-1.0-1.3
Bone: cortical porosity0.30.41.40.3-0.2-0.4-0.5-1.20.30.30.40.30.70.60.70.70.70.60.70.8
Bone: cortical porosity0.40.41.40.4-0.3-0.3-0.5-1.20.50.20.60.20.70.60.80.70.70.60.70.8
Bone: cortical thickness0.20.31.1-1.1-0.50.50.81.00.2-1.00.0-0.4-0.1-0.2-0.3-0.3-0.3-0.1-0.1-0.1
Bone: cortical thickness0.40.42.10.20.8-0.5-0.1-0.0-1.30.4-1.40.3-0.7-0.2-0.5-0.4-0.4-0.7-0.6-0.5
Bone: cortical tissue density0.30.41.4-1.1-0.80.40.61.00.6-1.20.6-0.00.60.30.20.30.30.20.20.5
Condit. Reinf. active minus inactive responses1.21.32.70.20.31.01.30.9-0.40.3-1.0-1.3-1.2-1.4-1.4-1.5-1.5-1.6-1.7-1.1
Condit. Reinf. active-inactive response ratio1.01.12.30.40.31.01.20.4-0.20.2-0.8-1.3-1.1-1.4-1.3-1.3-1.3-1.4-1.5-1.0
Condit. Reinf. active responses0.60.81.5-0.1-0.11.01.20.90.10.2-0.4-1.1-0.7-1.1-1.1-1.0-1.0-1.1-1.2-0.8
Condit. Reinf. inactive responses0.00.00.2-0.2-0.20.10.20.50.10.20.2-0.10.0-0.0-0.1-0.0-0.0-0.0-0.0-0.1
Incentive salience index mean0.91.12.10.30.60.50.70.8-0.70.9-1.2-0.8-1.2-1.2-1.3-1.3-1.3-1.4-1.5-1.2
Condit. Reinf. lever presses0.30.41.80.40.9-0.7-0.70.2-1.01.3-0.90.5-0.6-0.1-0.3-0.3-0.3-0.3-0.4-0.6
Condit. Reinf. active minus inactive responses4.05.210.53.23.0-0.8-0.3-1.8-3.02.5-3.2-0.5-2.8-1.8-2.1-2.1-2.1-2.2-2.1-2.2
Condit. Reinf. active-inactive response ratio1.41.74.61.31.8-0.9-0.4-0.5-2.11.5-2.10.2-1.6-0.8-1.1-1.1-1.1-1.2-1.2-1.3
Condit. Reinf. active responses5.67.916.64.13.5-0.7-0.2-2.2-3.33.0-3.8-0.9-3.5-2.5-2.7-2.8-2.8-2.8-2.7-2.8
Condit. Reinf. inactive responses2.53.28.93.01.80.40.2-1.6-1.11.9-1.7-1.5-2.1-2.1-1.9-1.9-1.9-1.9-1.8-1.8
Condit. Reinf. lever presses7.410.328.95.44.8-2.7-2.3-4.7-4.54.1-4.30.9-3.2-1.2-1.7-1.7-1.7-1.8-1.8-2.1
Condit. Reinf. lever reinforcers received6.08.318.14.33.7-0.9-0.4-2.4-3.63.1-3.9-0.8-3.6-2.4-2.7-2.7-2.7-2.8-2.7-2.8
Conditioned reinforcement - actives0.50.82.50.71.2-1.5-1.6-1.3-0.71.3-0.01.1-0.30.50.20.20.20.80.70.1
Conditioned reinforcement - inactives0.71.02.8-0.6-0.6-0.5-1.0-0.51.2-0.11.10.81.21.11.11.01.01.71.60.9
Conditioned locomotion1.72.26.11.01.3-2.4-2.5-2.2-0.71.40.12.00.41.41.21.11.11.61.60.6
Patch foraging indifference point 0 sec1.01.96.62.62.0-0.9-1.0-2.5-1.51.4-1.7-0.0-1.3-0.8-0.9-0.8-0.8-1.0-0.8-0.7
Patch foraging indifference point AUC0.30.40.70.40.60.10.10.4-0.70.4-0.8-0.2-0.8-0.6-0.7-0.7-0.7-0.7-0.9-0.8
Delay disc. indifference point, 0s delay0.80.81.91.21.2-0.4-0.4-0.7-0.91.2-1.4-0.2-1.1-0.7-0.8-0.8-0.8-0.7-1.1-0.8
Delay disc. indifference point, 16s delay0.60.72.1-0.30.3-1.3-1.4-0.4-0.80.8-0.11.30.51.00.70.90.90.40.70.5
Delay disc. indifference point, 2s delay0.40.51.61.21.2-0.9-0.8-1.3-0.61.1-0.40.5-0.6-0.0-0.3-0.2-0.20.2-0.2-0.3
Delay disc. indifference point, 24s delay0.30.31.2-1.1-0.4-0.3-0.20.90.0-0.30.80.60.50.60.60.50.50.40.50.4
Delay disc. indifference point, 4s delay1.51.54.21.31.9-0.8-0.9-0.5-1.42.1-1.40.1-1.6-0.9-1.2-1.2-1.2-0.8-0.9-1.4
Delay disc. indifference point, 8s delay0.50.62.2-0.10.8-1.3-1.5-0.6-1.11.1-0.61.1-0.00.60.30.30.30.00.20.3
Indifference point function ln k0.50.93.60.70.4-1.2-1.2-1.9-0.30.70.20.90.60.91.00.90.90.81.30.8
Indifference point function log k0.50.93.60.70.4-1.2-1.2-1.9-0.30.70.20.90.60.91.00.90.90.81.30.8
Patch foraging total patch changes 0 sec0.91.85.62.31.9-0.9-1.0-2.4-1.61.4-1.70.1-1.3-0.7-0.9-0.7-0.7-0.9-0.7-0.6
Patch foraging total patch changes 12 sec0.91.22.31.31.20.20.0-0.2-0.81.1-0.9-0.8-1.5-1.3-1.5-1.4-1.4-1.1-1.1-1.3
Patch foraging total patch changes 18 sec1.52.33.92.01.9-0.2-0.4-0.6-1.71.5-1.8-0.6-1.9-1.4-1.7-1.6-1.6-1.7-1.6-1.6
Patch foraging total patch changes 24 sec0.71.12.71.01.00.40.2-0.2-1.00.3-1.3-0.7-1.3-1.2-1.3-1.3-1.3-1.5-1.7-1.0
Patch foraging total patch changes 6 sec0.10.21.80.80.6-0.4-0.3-1.3-0.30.3-0.40.1-0.3-0.1-0.2-0.1-0.10.0-0.00.2
Patch foraging time to switch 0 sec1.42.97.0-2.6-2.61.40.91.92.6-2.02.4-0.41.90.81.01.01.01.21.21.3
Patch foraging water rate 0 sec1.02.25.62.32.4-1.4-1.3-2.1-2.21.9-1.90.6-1.4-0.4-0.8-0.6-0.6-0.8-1.0-0.8
Patch foraging water rate 12 sec0.51.13.21.71.6-1.3-1.2-1.8-1.51.4-1.20.8-0.60.2-0.1-0.0-0.0-0.2-0.2-0.3
Patch foraging water rate 18 sec0.50.82.01.11.3-0.5-0.4-0.7-1.31.4-1.40.2-0.9-0.4-0.7-0.5-0.5-1.0-1.0-0.6
Patch foraging water rate 24 sec0.71.12.90.81.1-1.5-1.7-1.4-1.01.1-0.51.60.21.00.70.70.70.70.70.5
Patch foraging water rate 6 sec0.40.61.70.60.7-1.2-1.3-1.2-0.90.6-0.51.10.20.70.70.70.70.30.30.4
Seeking ratio, delayed vs. immediate footshock0.30.32.4-1.5-0.60.1-0.21.30.5-0.30.20.30.40.40.30.10.10.20.30.3
Distance traveled before self-admin0.20.21.0-0.6-0.60.60.80.50.5-1.00.4-0.10.40.10.10.10.10.0-0.10.4
Distance traveled after self-admin1.61.93.9-1.4-1.90.60.60.01.7-2.01.40.21.91.21.51.51.51.31.21.7
Extensor digitorum longus weight0.41.73.10.10.61.00.91.4-0.40.9-1.0-1.2-1.6-1.7-1.7-1.7-1.7-1.5-1.5-1.8
Bone: elastic displacement0.50.62.0-1.4-0.8-0.2-0.00.70.5-0.40.50.60.90.90.80.90.90.80.70.8
Bone: elastic work1.31.73.4-1.8-1.0-0.8-0.70.40.5-0.90.91.41.51.71.61.61.61.61.51.5
Bone: endosteal estimation1.43.05.12.01.9-0.10.20.0-1.72.0-1.9-0.8-2.3-1.8-2.0-2.0-2.0-1.8-1.8-2.1
Bone: endosteal perimeter1.73.57.12.72.6-0.8-0.7-0.7-2.32.5-2.2-0.2-2.4-1.5-1.9-1.9-1.9-1.6-1.5-2.2
Epididymis fat weight0.72.57.0-1.3-1.12.52.62.11.8-1.41.0-2.2-0.6-1.6-1.5-1.4-1.4-0.5-0.9-0.8
Delta time in closed arm before/after self-admin0.60.61.7-0.50.30.10.21.3-1.10.2-1.1-0.1-0.7-0.5-0.7-0.7-0.7-1.3-1.0-0.8
Delta time in open arm before/after self-admin1.21.23.71.91.7-0.5-0.3-0.9-1.21.5-0.9-0.1-1.4-0.9-1.1-1.0-1.0-0.7-0.7-1.1
Diff in mean of infusions in LGA sessions2.93.57.8-2.7-2.61.41.72.12.6-2.42.8-0.31.80.91.11.21.21.81.51.4
Delay discount exponential model param0.40.51.5-0.0-0.81.21.20.60.9-1.00.4-1.00.1-0.5-0.3-0.3-0.3-0.2-0.2-0.2
Extinction: sum of active levers before priming0.30.40.70.50.60.20.10.2-0.50.4-0.4-0.4-0.8-0.7-0.8-0.8-0.8-0.8-0.8-0.6
Active lever presses in extinction session 61.61.66.60.3-0.2-0.8-1.1-2.60.4-0.30.61.11.41.41.51.61.61.30.91.8
Bone: final force0.10.20.5-0.40.3-0.7-0.3-0.3-0.5-0.1-0.30.7-0.00.50.20.20.20.50.60.3
Bone: final moment0.10.10.4-0.20.4-0.6-0.2-0.3-0.50.1-0.40.6-0.20.30.10.10.10.40.50.2
Food consumed during 24 hour testing period1.01.44.31.91.3-1.6-1.9-2.1-0.61.60.11.10.10.70.50.50.50.90.90.2
Glucose0.30.41.10.40.9-0.20.10.5-0.60.6-0.60.0-1.0-0.5-0.9-0.8-0.8-0.2-0.3-0.9
Heart weight0.20.21.00.40.7-0.3-0.1-0.8-0.80.3-1.00.1-0.5-0.2-0.4-0.2-0.2-0.5-0.4-0.0
Delay discount hyperbolic model param0.40.51.4-0.2-1.01.21.20.51.0-1.20.5-0.90.4-0.30.0-0.0-0.00.00.10.1
Intermittent access intake day 1-15 change0.61.24.11.21.1-1.6-1.9-2.0-0.71.0-0.51.30.20.80.60.60.60.70.80.5
Intermittent access intake escalation0.71.44.61.21.3-1.9-2.0-2.2-0.91.0-0.61.50.10.90.70.70.70.80.90.6
Intermittent access intake escalation 20.50.52.20.80.9-1.1-1.4-1.5-0.30.8-0.20.7-0.10.40.10.10.10.50.40.3
Intermitt. access day 1 inactive lever presses0.31.32.4-1.5-1.50.30.10.81.4-1.40.90.31.51.01.31.11.11.21.20.8
Intermitt. access day 15 inactive lever presses0.71.53.2-1.7-1.80.70.40.91.7-1.81.10.01.50.91.21.01.01.11.30.9
Intermitt. access escalation Index0.40.61.3-0.2-0.4-0.5-0.2-0.00.5-0.60.70.80.91.00.91.01.01.10.80.7
Intermittent access day 1 total infusions0.30.61.90.81.1-1.2-1.4-0.9-0.71.2-0.20.9-0.40.30.0-0.0-0.00.50.3-0.2
Intermittent access day 15 total infusions1.52.27.81.41.8-2.5-2.8-2.2-1.01.8-0.32.0-0.11.10.60.50.51.31.00.2
Intermittent access terminal intake (last 3 days)1.01.35.11.31.5-1.8-2.2-1.8-0.61.8-0.11.2-0.40.50.10.10.10.90.7-0.2
Intermittent access total infusions0.80.93.01.11.5-1.4-1.7-1.1-0.61.70.10.9-0.70.1-0.3-0.3-0.30.60.4-0.5
Intermittent access day 1 locomotion0.60.72.10.20.3-1.3-1.3-0.70.20.60.81.10.40.90.80.70.71.51.10.4
Intermittent access day 15 total locomotion0.61.03.61.30.8-1.4-1.8-1.9-0.01.00.11.00.30.70.70.60.61.21.10.3
Intermittent access total locomotion0.50.61.80.90.8-0.9-1.3-1.10.21.10.70.6-0.20.30.10.00.01.11.0-0.2
Intermittent access standard deviation0.30.71.40.70.50.60.10.10.00.7-0.1-0.9-1.0-1.2-1.1-1.2-1.2-0.8-0.9-1.2
Left kidney weight0.94.49.81.10.12.62.31.30.50.4-0.4-3.1-2.0-3.0-2.7-2.5-2.5-2.5-2.3-2.2
Right kidney weight1.25.310.81.60.32.72.61.20.20.6-0.8-3.3-2.3-3.2-3.0-2.7-2.7-2.7-2.6-2.6
Cocaine induced anxiety0.71.02.6-1.5-1.61.21.21.61.4-1.20.9-0.90.6-0.10.10.00.00.40.50.3
Post-drug Anxiety0.40.41.9-1.4-1.00.60.61.30.5-0.8-0.1-0.30.50.10.00.00.00.10.30.3
Baseline Anxiety0.60.72.20.71.2-1.0-1.2-0.6-1.41.1-1.50.9-0.50.2-0.1-0.1-0.1-0.5-0.3-0.4
Tail length1.87.113.41.70.92.72.91.4-0.31.0-1.4-3.4-2.9-3.7-3.4-3.3-3.3-3.1-3.1-3.0
Length with tail1.56.413.71.00.13.23.31.40.80.3-0.6-3.7-2.5-3.6-3.3-3.2-3.2-2.6-2.6-2.5
Length without tail0.41.33.9-0.8-1.31.91.80.62.0-1.41.3-1.60.2-0.8-0.6-0.5-0.50.00.10.2
Times rat made contact with spout0.60.61.8-0.2-0.71.31.11.01.1-0.61.1-1.2-0.1-0.8-0.6-0.6-0.6-0.2-0.1-0.4
Lifetime Intake0.91.14.11.21.5-1.7-2.0-1.4-0.91.8-0.11.2-0.50.4-0.0-0.0-0.00.50.4-0.3
Liver weight, left0.81.42.70.00.01.51.51.00.8-0.4-0.0-1.6-1.2-1.6-1.6-1.6-1.6-0.8-1.2-1.1
Liver weight, right2.74.710.8-0.6-0.93.33.12.41.6-0.70.5-3.3-1.5-2.8-2.5-2.5-2.5-1.8-2.0-1.7
Locomotor activity0.30.41.51.2-0.10.80.3-0.6-0.00.40.0-1.1-0.2-0.8-0.3-0.4-0.4-1.1-0.8-0.5
Locomotor testing distance1.42.65.81.91.01.00.6-0.3-1.21.1-1.3-1.8-1.7-2.0-1.7-1.8-1.8-2.4-2.1-1.8
Locomotor testing rearing1.53.16.30.80.22.11.70.8-0.2-0.2-0.7-2.5-1.7-2.4-2.1-2.3-2.3-2.4-2.2-1.7
Locomotion in novel chamber1.11.44.10.80.8-2.0-1.6-1.5-0.10.80.51.50.31.11.00.90.91.81.70.4
Locomotion in novel chamber post-restriction1.32.27.11.41.8-2.7-2.0-2.6-1.31.1-0.72.0-0.11.20.80.80.81.21.10.7
Fecal boli incidents, locomotor time 11.11.65.40.81.3-2.0-2.0-1.1-2.01.4-2.31.7-0.10.90.50.70.7-0.2-0.20.1
Change in fecal boli incidents, locomotor task0.80.82.0-1.1-1.40.90.90.31.3-1.41.2-0.60.90.20.60.40.40.50.70.9
Time >=10cm from walls, locomotor time 11.01.13.30.91.0-1.6-1.4-1.8-1.00.8-0.51.40.21.00.71.01.00.70.70.6
Bouts of movement, locomotor time 10.30.32.30.60.8-0.7-0.2-0.3-0.90.4-1.50.5-0.50.0-0.2-0.2-0.2-0.2-0.2-0.3
Total resting periods, locomotor time 10.30.31.40.10.5-0.9-0.6-0.4-0.50.1-1.20.90.10.60.40.30.30.40.50.3
Rest time, locomotor task time 10.60.82.0-0.60.2-1.3-1.0-0.6-0.60.1-0.51.40.61.21.00.90.90.70.91.1
Distance moved, locomotor task time 11.01.53.31.00.70.80.60.8-0.40.9-0.6-1.3-1.5-1.6-1.7-1.5-1.5-1.4-1.6-1.8
Vertical activity count, locomotor time 10.40.92.11.00.70.50.30.4-0.40.7-0.5-0.9-1.2-1.2-1.3-1.1-1.1-1.1-1.4-1.4
Time >=10cm from walls, locomotor time 20.50.81.91.21.4-0.6-0.3-0.8-1.30.7-1.20.1-1.1-0.6-0.6-0.7-0.7-0.8-1.0-0.6
Bouts of movement, locomotor time 20.30.51.51.10.7-0.1-0.5-0.8-0.31.2-0.5-0.5-0.7-0.7-0.7-0.7-0.7-0.4-0.4-0.8
Total resting periods, locomotor time 20.20.31.10.80.5-0.2-0.5-0.6-0.31.0-0.5-0.3-0.5-0.5-0.5-0.5-0.5-0.3-0.3-0.6
Rest time, locomotor task time 21.01.33.4-1.8-1.50.50.51.11.1-1.41.30.11.30.81.01.21.20.81.21.3
Distance moved, locomotor task time 22.12.54.92.22.1-0.4-0.4-0.7-1.41.9-1.4-0.5-2.1-1.5-1.7-1.9-1.9-1.3-1.7-1.9
Vertical activity count, locomotor time 21.52.03.81.61.50.10.0-0.1-1.21.4-1.5-0.7-1.8-1.5-1.7-1.7-1.7-1.5-1.8-1.9
Light reinforcement 10.51.35.0-1.3-1.51.82.21.51.2-1.70.6-1.20.4-0.5-0.3-0.1-0.1-0.4-0.30.2
Light reinforcement 20.10.20.70.0-0.50.20.8-0.50.4-0.70.3-0.20.40.20.30.40.40.30.30.5
Bone: marrow area1.22.74.61.91.80.00.30.1-1.61.9-1.8-0.8-2.1-1.7-1.9-1.9-1.9-1.7-1.7-2.0
Bone: maximum diameter1.22.34.52.02.0-0.4-0.1-0.8-1.71.5-1.8-0.5-2.1-1.5-1.7-1.7-1.7-1.3-1.2-1.7
Bone: maximum force0.20.41.5-0.30.5-1.2-0.6-0.5-0.7-0.1-0.31.10.10.80.50.50.51.00.90.5
Bone: maximum moment0.20.31.2-0.10.5-1.1-0.5-0.6-0.70.0-0.31.0-0.00.60.40.30.30.80.70.3
Mean time between licks in bursts1.64.08.42.92.10.3-0.0-0.7-1.42.5-1.8-1.4-2.5-2.2-2.3-2.3-2.3-2.0-2.0-2.4
Mean num. licks in bursts1.01.54.82.21.9-1.4-1.6-1.7-1.62.0-1.10.7-1.0-0.1-0.4-0.4-0.4-0.3-0.1-0.7
Cd content in liver0.70.82.0-0.4-0.11.01.31.4-0.2-0.6-0.5-0.9-0.8-1.0-1.0-1.0-1.0-1.1-1.1-0.8
Co content in liver1.11.32.31.31.3-0.1-0.1-0.0-1.31.1-1.5-0.5-1.4-1.1-1.3-1.2-1.2-1.3-1.4-1.4
Cu content in liver2.22.64.81.00.51.51.31.0-0.50.6-1.0-1.9-1.7-2.1-2.0-2.0-2.0-2.2-2.2-1.8
Fe content in liver0.00.00.1-0.20.2-0.1-0.10.1-0.10.3-0.20.1-0.2-0.0-0.1-0.0-0.00.10.0-0.1
K content in liver0.30.21.3-0.2-0.80.60.10.31.0-0.21.2-0.50.5-0.10.10.20.20.20.20.3
Mg content in liver0.10.10.20.4-0.1-0.1-0.3-0.50.10.30.3-0.10.20.10.20.20.20.10.10.2
Mn content in liver1.41.52.5-1.2-1.2-0.5-0.5-0.01.0-1.01.40.81.61.41.51.51.51.51.51.5
Na content in liver0.40.52.10.6-0.1-0.4-0.9-1.50.40.20.70.20.70.50.70.70.70.70.60.7
Rb content in liver0.10.10.20.20.10.40.40.20.10.1-0.1-0.4-0.3-0.4-0.4-0.4-0.4-0.3-0.2-0.3
Se content in liver2.42.97.6-2.8-2.50.70.71.52.0-2.22.30.02.01.11.41.41.41.21.21.7
Sr content in liver0.30.20.70.20.6-0.8-0.6-0.6-0.80.3-0.50.8-0.10.40.20.20.20.20.20.2
Zn content in liver2.73.04.82.11.60.40.3-0.2-1.52.0-1.8-1.2-2.1-1.9-2.0-1.9-1.9-2.2-2.2-1.9
Bone: minimum diameter1.63.05.21.01.10.81.31.0-1.10.7-1.6-1.5-2.2-2.1-2.3-2.3-2.3-2.1-2.1-2.1
Time in familiar zone, hab. session 10.00.00.1-0.10.1-0.2-0.10.30.00.00.10.2-0.10.10.00.00.00.20.1-0.2
Time in novel zone, hab. session 10.40.40.8-0.2-0.30.80.80.50.0-0.1-0.3-0.9-0.4-0.7-0.6-0.6-0.6-0.9-0.9-0.3
Total zone transitions, hab. session 10.71.02.2-0.4-0.8-0.4-0.0-1.00.7-0.91.00.51.31.11.31.31.31.21.31.5
Total locomotion distance, hab. session 12.94.112.0-1.1-2.33.43.52.02.7-2.11.8-3.10.0-1.8-1.2-1.2-1.2-1.1-1.0-0.4
Locomotion velocity, hab. session 12.43.410.0-1.0-2.23.23.21.72.6-2.11.7-2.90.1-1.6-1.0-1.0-1.0-0.9-0.8-0.3
Time in familiar zone, hab. session 20.60.61.51.21.1-0.2-0.5-0.1-0.71.0-0.5-0.1-1.0-0.7-0.8-0.9-0.9-0.5-0.6-1.2
Time in novel zone, hab. session 20.10.10.3-0.30.0-0.3-0.0-0.2-0.4-0.1-0.50.30.10.20.10.20.2-0.1-0.00.3
Total zone transitions, hab. session 20.40.63.00.4-0.1-0.6-0.1-1.7-0.0-0.20.20.50.70.80.90.90.90.70.71.1
Total locomotion distance, hab. session 22.02.78.5-0.4-1.52.72.91.31.6-1.30.7-2.7-0.4-1.8-1.3-1.3-1.3-1.5-1.4-0.7
Locomotion velocity, hab. session 22.33.19.7-0.5-1.52.93.11.41.7-1.40.8-2.9-0.4-1.9-1.4-1.4-1.4-1.6-1.5-0.7
Novel to familiar place preference ratio0.10.10.40.0-0.20.20.3-0.70.2-0.20.1-0.20.20.00.20.20.20.20.30.4
Novelty place preference0.00.00.20.10.00.10.1-0.50.00.0-0.1-0.10.0-0.00.00.00.00.00.20.2
Time in novel zone, NPP test0.10.10.40.30.3-0.2-0.1-0.6-0.20.3-0.30.1-0.10.00.00.00.00.00.20.1
Total zone transitions, NPP test0.50.71.5-0.20.1-1.2-0.8-0.9-0.60.0-0.21.20.71.21.11.11.10.80.81.0
Total locomotion distance, NPP test1.52.16.1-1.0-1.32.32.51.71.3-1.50.5-2.1-0.3-1.5-1.1-1.1-1.1-1.3-1.3-0.6
Locomotion velocity, NPP test1.82.67.9-1.2-1.72.62.81.91.6-1.90.8-2.4-0.2-1.5-1.1-1.1-1.1-1.3-1.2-0.5
Intraocular pressure1.92.88.80.82.0-3.0-2.9-1.2-2.22.0-1.52.7-0.21.50.80.80.80.81.0-0.0
Delta distance traveled before/after self-admin0.60.61.40.1-0.7-0.2-0.5-1.20.8-0.20.50.21.10.71.01.01.00.90.81.0
Delta ambulatory time before/after self-admin0.60.71.50.1-0.6-0.4-0.6-1.20.6-0.20.50.41.10.91.21.21.21.00.91.0
Parametrial fat weight0.61.46.9-1.3-1.51.82.60.71.5-2.00.8-1.50.4-0.6-0.2-0.1-0.1-0.2-0.10.6
Pavlov. Cond. lever latency0.70.93.5-1.3-1.41.01.10.61.2-1.91.1-0.41.00.40.60.60.60.40.50.9
Pavlov. Cond. magazine entry latency1.41.94.51.91.8-0.6-0.5-1.1-1.72.1-1.7-0.2-1.6-1.1-1.2-1.3-1.3-1.1-1.1-1.3
Pavlov. Cond. change in total contacts0.80.92.81.11.4-0.9-0.9-0.6-1.31.7-1.30.4-1.0-0.4-0.7-0.7-0.7-0.4-0.6-0.8
Pavlov. Cond. index score1.62.05.21.81.8-0.7-0.8-0.7-1.82.3-1.7-0.1-1.7-1.1-1.3-1.3-1.3-1.2-1.3-1.5
Pavlov. Cond. latency score1.31.74.41.71.7-0.7-0.7-0.7-1.52.1-1.5-0.1-1.6-1.0-1.2-1.2-1.2-1.0-1.0-1.4
Pavlov. Cond. lever contacts0.80.93.31.11.2-0.6-0.8-0.2-1.21.8-1.10.1-1.1-0.6-0.8-0.8-0.8-0.7-0.8-1.1
Pavlov. Cond. magazine entry number1.72.25.2-2.0-1.90.60.61.01.8-2.31.90.31.71.11.41.31.31.31.31.5
Pavlov. Cond. intertrial magazine entries0.50.61.6-1.2-1.21.00.91.21.2-1.20.9-0.50.70.00.20.20.20.1-0.00.3
Pavlov. Cond. lever-magazine prob. diff.1.31.64.71.71.7-0.8-0.9-0.6-1.62.2-1.50.0-1.5-0.8-1.1-1.1-1.1-1.0-1.0-1.3
Pavlov. Cond. response bias0.81.03.61.21.2-0.5-0.7-0.3-1.31.9-1.3-0.1-1.1-0.7-0.9-0.9-0.9-0.9-1.0-1.0
Pavlov. Cond. lever latency8.511.630.1-5.5-5.13.43.05.05.1-4.64.6-1.53.00.81.31.31.31.71.61.9
Pavlov. Cond. magazine entry latency3.03.610.52.32.7-2.8-2.4-2.9-3.22.0-2.72.0-1.00.70.20.20.2-0.2-0.3-0.3
Pavlov. Cond. change in total contacts4.77.620.04.54.1-2.4-2.0-4.1-4.03.6-3.80.9-2.7-1.0-1.3-1.3-1.3-1.6-1.5-1.7
Pavlov. Cond. index score6.79.121.94.64.6-3.3-2.8-4.4-4.73.9-4.21.7-2.6-0.5-1.0-1.0-1.0-1.3-1.4-1.6
Pavlov. Cond. latency score6.18.020.14.34.3-3.3-2.8-4.3-4.53.6-3.91.8-2.3-0.2-0.7-0.7-0.7-1.1-1.1-1.3
Pavlov. Cond. lever contacts7.910.928.35.34.9-3.1-2.7-4.8-4.94.4-4.61.3-3.0-0.9-1.4-1.4-1.4-1.9-1.7-1.9
Pavlov. Cond. magazine entry number5.77.020.4-3.2-4.13.63.23.04.5-3.53.8-2.52.0-0.30.40.40.40.70.81.3
Pavlov. Cond. intertrial magazine entries1.52.36.40.5-0.52.22.01.00.8-0.30.1-2.5-1.0-2.1-1.7-1.7-1.7-1.8-1.6-1.2
Pavlov. Cond. lever-magazine prob. diff.6.58.721.24.54.5-3.1-2.7-4.2-4.63.8-4.21.5-2.6-0.5-1.1-1.1-1.1-1.4-1.4-1.6
Pavlov. Cond. response bias8.812.028.55.35.2-3.5-3.1-4.8-5.34.7-4.91.7-3.1-0.7-1.3-1.3-1.3-1.8-1.8-2.0
Time in closed arm before self-admin0.60.71.90.40.1-0.9-1.4-1.20.10.50.40.80.70.91.01.01.00.91.10.7
Time in closed arm after self-admin1.51.63.2-1.1-0.4-1.5-1.6-0.0-0.20.10.41.81.31.81.71.71.71.31.51.0
Time in open arm before self-admin0.80.82.4-1.5-1.31.31.41.50.7-1.5-0.1-0.70.5-0.1-0.0-0.0-0.0-0.4-0.40.3
Time in open arm after self-admin1.01.12.40.80.31.21.50.30.2-0.2-0.4-1.4-1.1-1.4-1.3-1.3-1.3-1.0-1.1-0.9
Bone: periosteal estimation1.53.26.21.72.1-0.20.30.1-2.01.7-2.2-0.7-2.5-1.8-2.1-2.1-2.1-1.8-1.7-2.2
Bone: periosteal perimeter1.22.13.81.91.7-0.00.1-0.2-1.41.4-1.5-0.7-2.0-1.5-1.7-1.7-1.7-1.5-1.4-1.8
Bone: post-yield work0.10.20.5-0.0-0.2-0.20.1-0.50.2-0.70.50.10.30.30.30.30.30.70.60.5
Progressive ratio test 1 active lever presses0.60.81.6-0.5-0.1-1.0-1.1-0.40.40.11.01.10.81.11.01.01.01.31.20.8
Progressive ratio test 1 breakpoint0.60.81.7-0.5-0.1-1.1-1.1-0.40.30.10.91.10.81.11.01.01.01.31.20.8
Progressive ratio test 1 inactive lever presses0.81.22.1-1.3-1.1-0.2-0.6-0.11.0-0.90.80.71.51.21.31.41.41.21.41.2
Progressive ratio test 2 active lever presses0.70.82.91.21.6-1.0-1.1-0.6-0.81.7-0.30.6-1.0-0.3-0.7-0.6-0.60.0-0.3-1.0
Progressive ratio test 2 breakpoint0.70.93.01.21.6-1.0-1.2-0.6-0.81.7-0.40.7-1.0-0.2-0.7-0.6-0.60.0-0.3-1.0
Progressive ratio test 2 inactive lever presses0.10.21.00.40.5-0.5-1.0-0.3-0.10.80.10.4-0.20.1-0.20.00.00.30.5-0.5
Incentive Sensitization - Responses1.01.43.81.61.8-0.5-0.8-0.8-1.11.9-0.90.1-1.5-0.9-1.2-1.1-1.1-0.6-1.0-1.5
Incentive Sensitization - Breakpoint1.01.33.61.61.7-0.5-0.8-0.7-0.91.9-0.80.1-1.4-0.8-1.2-1.0-1.0-0.6-0.9-1.5
Sum of active levers in priming session hrs 5-60.20.20.80.4-0.40.90.8-0.40.8-0.50.6-0.80.1-0.4-0.0-0.0-0.00.0-0.10.0
Progressive ratio0.61.02.80.41.0-1.7-1.4-0.7-1.60.7-1.21.60.11.00.70.70.70.20.20.3
Food seeking constrained by brief footshock1.51.84.21.91.10.60.8-1.3-1.40.5-1.7-1.2-1.4-1.5-1.4-1.4-1.4-2.0-1.5-0.9
Seeking ratio, punishment vs. effort1.62.36.61.0-0.12.21.7-0.00.8-0.10.0-2.6-1.2-2.2-1.8-1.8-1.8-1.6-1.5-1.2
Retroperitoneal fat weight3.514.742.3-1.8-2.15.96.54.73.1-2.31.2-5.7-2.2-4.6-4.0-3.8-3.8-2.9-3.1-2.5
Reaction time number correct0.51.02.6-0.5-1.00.1-0.1-1.10.7-1.01.00.31.51.01.31.31.30.71.01.6
Reaction time mean minus median0.30.81.81.30.9-0.10.2-0.8-0.70.8-0.9-0.6-1.1-1.0-0.8-1.0-1.0-1.0-0.7-0.9
Reaction time mean minus median AUC0.10.41.71.20.8-0.4-0.1-1.3-0.50.6-0.5-0.2-0.7-0.5-0.3-0.5-0.5-0.4-0.3-0.3
Reaction time num false alarms0.60.95.0-1.5-1.11.31.32.20.8-1.20.5-0.80.1-0.4-0.5-0.3-0.3-0.3-0.3-0.4
Reaction time num false alarms AUC0.20.32.7-1.0-0.60.60.41.60.4-0.60.3-0.20.1-0.0-0.20.00.0-0.10.0-0.3
Reaction time trials correct on left0.51.02.6-0.5-1.00.1-0.1-1.10.7-1.01.00.31.51.01.31.31.30.71.01.6
Reaction time trials on left0.51.02.5-0.4-1.00.0-0.1-1.10.6-0.91.00.31.51.01.31.31.30.71.01.6
Reaction time mean0.10.21.0-0.2-0.40.71.00.20.3-0.4-0.1-0.7-0.2-0.5-0.4-0.3-0.3-0.4-0.2-0.2
Reaction time mean AUC0.10.10.5-0.5-0.50.50.70.40.4-0.50.1-0.30.1-0.1-0.0-0.0-0.0-0.10.0-0.0
Median of all reaction times0.10.20.7-0.6-0.70.70.90.40.5-0.60.1-0.40.3-0.1-0.00.10.1-0.10.10.1
Reaction time omissions0.60.92.10.70.70.40.1-0.2-0.90.7-1.4-0.6-1.1-1.0-0.9-1.1-1.1-1.5-1.2-1.0
Reaction time false alarm rate0.30.43.9-0.9-0.20.40.52.00.1-0.3-0.1-0.1-0.4-0.3-0.6-0.5-0.5-0.2-0.3-0.8
Reaction time premature initiation rate2.83.87.61.50.91.71.40.3-0.31.1-1.2-2.4-2.2-2.7-2.5-2.6-2.6-2.5-2.2-2.1
Reaction time premature initiations1.01.83.81.20.41.41.0-0.4-0.10.7-0.7-1.9-1.3-1.9-1.6-1.7-1.7-1.9-1.5-1.1
Std. dev. reaction times0.71.22.11.00.70.60.7-0.1-0.60.7-1.1-1.1-1.4-1.4-1.3-1.4-1.4-1.5-1.1-1.3
Reaction time trials completed0.51.02.5-0.4-1.00.0-0.1-1.10.6-0.91.00.31.51.01.31.31.30.71.01.6
Reaction time trials AUC0.40.72.0-0.3-0.90.20.1-1.10.6-0.90.80.01.20.81.01.11.10.40.71.4
Run reversals in cocaine runway, females2.62.64.60.40.41.61.51.9-0.60.4-1.0-1.6-1.6-1.9-2.0-2.0-2.0-2.1-2.0-2.0
Run reversals in cocaine runway, males0.90.92.8-0.30.8-1.7-1.6-0.5-0.81.0-0.51.60.21.10.80.70.70.60.50.5
Latency to leave start box in cocaine runway1.01.23.1-1.5-1.81.51.31.41.5-1.71.2-0.90.9-0.10.10.20.2-0.20.00.6
Latency to leave start box in cocaine runway, F1.21.43.8-1.1-1.52.01.61.81.2-1.40.8-1.50.1-0.9-0.6-0.7-0.7-1.0-0.7-0.3
Latency to leave start box in cocaine runway, M0.60.61.0-0.8-0.7-0.2-0.4-0.20.8-0.60.90.51.00.80.90.90.90.90.91.0
Std. dev. time between licks in bursts1.72.34.61.40.31.71.40.30.00.2-0.6-2.2-1.4-2.1-1.8-1.9-1.9-1.9-2.1-1.6
Total sessions with >9 infusions0.81.03.01.21.3-1.5-1.7-1.5-1.21.6-0.71.0-0.40.40.10.10.1-0.00.2-0.1
Short access day 1 total inactive lever presses0.30.41.30.40.7-0.9-1.2-0.5-1.00.7-0.90.8-0.10.40.20.10.1-0.20.2-0.2
Short access day 10 total inactive lever presses0.61.53.8-1.8-1.91.30.90.91.9-1.91.3-0.61.40.40.80.70.70.60.60.9
Short access day 1 total infusions1.11.53.81.91.9-1.1-1.4-1.6-1.41.9-0.90.4-1.2-0.5-0.8-0.7-0.7-0.7-0.4-0.8
Short access day 10 total infusions0.70.92.41.01.5-1.4-1.3-0.9-1.51.5-0.90.9-0.80.1-0.3-0.3-0.3-0.3-0.2-0.5
Short access total infusions1.01.34.11.41.7-1.8-2.0-1.5-1.51.9-0.71.2-0.60.4-0.10.00.0-0.00.1-0.3
Short access day 1 locomotion1.51.95.31.31.7-2.3-2.3-2.3-1.51.4-1.01.8-0.11.00.70.50.50.60.70.3
Short access day 10 total locomotion0.40.82.31.51.4-1.1-1.2-1.2-0.91.5-0.90.4-0.8-0.2-0.3-0.5-0.5-0.00.2-0.7
Short access total locomotion0.40.51.90.80.5-1.1-1.2-1.4-0.10.60.10.80.30.60.60.40.40.80.90.3
One hour access (0.3 mA shock)0.60.71.71.11.3-0.8-1.0-0.8-0.91.3-0.50.4-0.9-0.3-0.6-0.7-0.7-0.3-0.6-0.7
Compulsive drug intake0.60.71.6-0.8-1.10.30.2-0.11.1-1.20.80.11.20.80.91.01.00.90.81.0
One hour access (shock baseline)0.91.43.81.51.8-1.7-1.8-1.4-1.52.0-1.01.1-0.90.1-0.3-0.4-0.40.0-0.1-0.5
Social response proportion1.01.23.2-1.0-1.71.81.30.91.8-1.41.6-1.50.6-0.6-0.1-0.2-0.2-0.00.10.3
Social responses1.31.64.6-0.7-1.12.11.91.61.1-1.20.4-1.9-0.4-1.4-1.1-1.2-1.2-1.3-0.9-0.7
Social time1.11.54.3-2.1-2.11.41.31.21.5-2.01.2-0.71.30.30.70.60.60.10.31.1
Soleus weight1.03.05.6-0.1-0.32.12.21.90.50.1-0.3-2.4-1.5-2.2-2.1-2.1-2.1-1.7-2.1-1.8
Bone: stiffness0.30.41.4-1.1-0.5-0.20.20.10.4-1.20.50.50.50.60.50.60.61.00.90.8
Tibialis anterior weight0.20.61.50.40.01.10.90.10.40.2-0.2-1.2-0.7-1.1-0.9-0.9-0.9-0.8-0.8-0.7
Time to tail flick, vehicle, before self-admin0.10.10.8-0.20.20.20.10.5-0.40.3-0.9-0.1-0.3-0.3-0.3-0.3-0.3-0.6-0.2-0.5
Time to tail flick, vehicle, after self-admin0.50.72.20.91.1-1.0-1.1-1.0-1.51.3-1.30.5-0.5-0.0-0.0-0.0-0.0-0.7-0.3-0.5
Time to tail flick, test, before self-admin0.60.61.60.41.1-0.30.40.6-1.30.7-0.70.0-1.2-0.6-0.9-0.9-0.9-0.8-0.7-0.9
Time to tail flick, test, after self-admin1.11.13.30.80.80.10.50.5-1.30.8-1.8-0.5-1.2-1.0-0.9-1.0-1.0-1.6-1.4-1.4
Delta time to tail flick, vehicle, before/after SA0.70.72.50.80.8-1.3-1.4-1.6-1.01.0-0.50.90.00.60.50.50.50.10.20.2
Delta time to tail flick, test, before/after SA0.30.31.2-0.4-1.10.70.40.10.9-1.00.2-0.50.80.20.60.50.50.10.10.4
Tibia length0.41.05.11.31.2-1.4-1.1-2.3-1.30.6-1.01.1-0.20.60.40.40.40.30.60.4
Ambulatory time before self-admin0.30.50.9-0.8-0.6-0.10.10.20.5-1.00.70.70.80.90.70.70.70.80.70.9
Ambulatory time after self-admin1.72.03.8-1.0-1.4-0.2-0.1-0.51.4-1.41.30.81.91.61.81.81.81.71.51.8
Bone: tissue strength3.13.16.2-1.7-1.7-0.2-0.1-0.52.0-1.62.30.82.11.71.91.91.92.52.42.1
Total heroin consumption0.10.10.8-0.3-0.30.40.40.10.4-0.20.9-0.20.1-0.00.20.10.10.0-0.20.2
Bone: trabecular number0.61.02.7-1.7-1.0-0.3-0.20.90.8-0.81.10.71.01.00.91.01.01.21.20.9
Bone: trabecular spacing0.30.42.01.30.8-0.5-0.5-1.4-0.90.5-0.90.2-0.20.00.10.10.1-0.5-0.40.0
Bone: trabecular thickness0.30.41.2-0.5-0.20.70.71.10.1-0.6-0.0-0.7-0.6-0.7-0.8-0.8-0.8-0.5-0.6-0.7
Bone: trabecular tissue density1.42.06.9-1.1-1.82.32.61.51.8-2.21.4-1.90.3-0.9-0.5-0.5-0.5-0.5-0.30.0
Water consumed over 24 hours0.40.61.9-1.0-1.10.60.30.91.2-0.71.4-0.30.70.20.40.40.40.60.70.5
Number of responses in last shaping day1.51.74.2-1.0-0.82.01.82.01.0-0.90.5-1.7-0.6-1.4-1.3-1.3-1.3-1.2-1.1-0.8