Hub : Genes

Map6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Map6 0.2 0.11 4.2e-15 0.16 0.16 0.17 0.17 2.3e-14 4.6e-15 7.5e-16 2.1e-15
2 Brain isoform ratio NM_001398600.1 0.03 0.02 6.6e-03 0.01 0.02 0.01 0.01 1.6e-02 2.7e-03 1.5e-02 2.2e-02
3 Liver intron excision ratio chr1_162982454_163017059 0.04 0.03 1.8e-04 0.03 0.02 0.02 0.02 3.1e-04 9.0e-04 3.0e-03 2.6e-03
4 Liver intron excision ratio chr1_162982454_163026215 0.04 0.03 1.5e-04 0.03 0.03 0.02 0.02 3.0e-04 6.2e-04 2.7e-03 2.9e-03
5 Brain mRNA stability Map6 0.13 0.08 1.9e-09 0.1 0.09 0.07 0.09 2.9e-09 8.0e-09 2.7e-07 7.0e-09
6 Brain alternative polyA NM_001398600.1 0.03 0.02 4.9e-03 0.02 0.02 0.01 0.01 1.1e-02 3.2e-03 2.5e-02 1.4e-02
7 Liver alternative polyA NM_001398602.1 0.05 0.04 2.1e-05 0.04 0.03 0.03 0.03 8.6e-05 2.5e-04 1.9e-04 2.0e-04
8 NAcc gene expression Map6 0.3 0.13 0.0e+00 0.22 0.22 0.22 0.22 1.9e-33 1.5e-32 4.4e-32 2.1e-33
9 Adipose alternative polyA NM_001398602.1 0.08 0.05 2.2e-08 0.07 0.07 0.07 0.07 2.1e-08 6.0e-08 8.7e-08 2.1e-08
10 PL isoform ratio NM_001398600.1 0.03 0.02 3.7e-03 0.02 0.01 0.01 0.01 3.7e-03 1.0e-02 8.4e-03 1.2e-02
11 NAcc alternative polyA NM_001398600.1 0.04 0.03 6.9e-07 0.04 0.04 0.04 0.03 3.3e-06 9.3e-07 3.0e-06 6.8e-06
12 IC gene expression Map6 0.2 0.12 8.4e-07 0.17 0.14 0.14 0.14 1.4e-07 1.2e-06 2.8e-06 1.2e-06
13 NAcc isoform ratio NM_001398600.1 0.04 0.03 5.2e-07 0.04 0.04 0.04 0.04 1.7e-06 4.1e-07 7.0e-07 1.6e-06
14 Adipose mRNA stability Map6 0.07 0.04 1.8e-05 0.03 0.04 0.03 0.03 2.5e-04 4.2e-05 4.2e-04 2.1e-04
15 pVTA alternative polyA NM_001398600.1 0.04 0.03 7.0e-04 0.02 0.04 0.03 0.03 8.1e-03 7.4e-04 1.9e-03 3.6e-03
16 OFC isoform ratio NM_001398600.1 0.19 0.14 2.4e-03 0.01 0.07 0.1 0.04 2.0e-01 8.1e-03 2.2e-03 3.3e-02
17 pVTA mRNA stability Map6 0.04 0.03 2.8e-03 0.03 0.03 0.04 0.03 1.7e-03 1.5e-03 7.9e-04 1.7e-03
18 PL gene expression Map6 0.07 0.04 2.8e-09 0.08 0.08 0.08 0.08 7.1e-09 6.9e-09 1.2e-08 4.1e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.10.10.70.30.2-0.10.1-0.70.2-0.1-0.10.1-0.60.30.00.2-0.40.1-0.80.50.2
Area under the delay curve0.10.10.5-0.5-0.0-0.10.10.2-0.1-0.1-0.2-0.30.6-0.2-0.2-0.10.1-0.20.7-0.3-0.1
BMI with tail0.20.73.70.5-0.2-0.40.40.5-0.5-0.5-0.2-0.40.3-0.9-0.3-0.9-1.0-1.30.91.91.6
BMI without tail0.52.910.3-0.1-1.1-1.41.41.3-1.5-1.4-1.3-1.31.3-1.8-1.2-1.9-0.7-2.42.03.22.7
Body weight0.52.47.9-0.2-0.8-1.01.01.1-1.2-1.1-0.8-1.01.2-1.7-0.8-1.7-1.1-2.32.22.82.7
Weight adjusted by age0.30.82.9-0.5-0.7-0.70.70.8-0.8-0.8-0.8-0.81.4-0.9-0.8-0.90.1-1.01.71.10.8
Bone surface1.42.84.5-1.7-1.7-2.02.01.2-1.8-2.1-1.8-1.81.3-1.6-1.7-1.80.8-1.70.31.91.8
Bone volume0.71.43.0-0.9-1.2-1.41.40.7-1.2-1.4-1.3-1.30.8-1.1-1.3-1.20.4-1.30.21.71.6
Breakpoint value in progressive ratio session0.81.42.01.11.21.2-1.2-1.21.31.11.21.2-1.01.31.21.3-0.51.3-1.0-1.4-1.3
Number of licking bursts1.64.87.52.72.52.4-2.4-2.42.32.32.32.2-2.72.02.52.0-2.71.4-1.1-1.1-1.0
Context. condit. distance diff. score2.12.64.7-1.8-1.9-1.81.81.4-1.7-2.0-1.8-2.01.6-1.4-1.9-1.42.2-1.0-0.40.90.7
Locomotion velocity, session 10.91.03.10.80.81.0-1.0-0.61.01.21.00.8-0.91.10.91.10.11.4-0.6-1.8-1.2
Locomotion distance, session 10.20.31.9-0.7-0.6-0.20.20.9-0.4-0.1-0.1-0.30.7-0.3-0.1-0.11.40.30.2-0.9-0.3
Locomotion velocity, session 20.10.11.30.0-0.1-0.10.10.4-0.1-0.0-0.20.10.1-0.20.1-0.10.1-0.11.1-0.3-0.1
Locomotion distance, session 20.20.31.2-0.4-0.6-0.40.40.8-0.5-0.3-0.5-0.50.6-0.4-0.5-0.40.9-0.11.1-0.2-0.1
Locomotion velocity, session 30.20.21.6-0.3-0.6-0.20.20.6-0.4-0.4-0.3-0.40.5-0.2-0.3-0.11.30.2-0.0-0.2-0.5
Locomotion distance, session 30.30.42.7-0.6-0.7-0.40.40.7-0.5-0.4-0.5-0.60.2-0.2-0.6-0.21.60.3-0.4-0.7-0.7
Stereotopy head waving bouts, day 30.20.21.00.60.60.4-0.4-0.40.40.50.30.4-0.40.20.40.2-1.0-0.00.00.00.4
Stereotopy head waving duration, day 30.20.20.4-0.6-0.5-0.50.50.3-0.5-0.5-0.6-0.60.7-0.4-0.6-0.40.5-0.30.30.40.0
Locomotion velocity, session 70.40.51.10.70.50.7-0.7-0.60.60.60.70.7-0.60.70.60.7-0.10.8-0.9-0.5-1.0
Locomotion distance, session 70.10.10.50.50.30.3-0.3-0.40.30.20.30.1-0.50.30.20.3-0.20.2-0.70.1-0.4
Stereotopy head waving bouts, day 71.41.63.4-1.7-1.5-1.41.41.5-1.3-1.2-1.3-1.31.4-1.1-1.4-1.11.8-0.71.3-0.00.2
Stereotopy head waving duration, day 72.32.84.2-2.0-1.9-1.81.81.9-1.8-1.7-1.7-1.72.0-1.6-1.7-1.61.9-1.21.70.70.8
Locomotion velocity, session 81.31.52.6-1.6-1.4-1.51.51.0-1.3-1.5-1.4-1.51.0-1.2-1.4-1.21.2-1.00.10.60.9
Locomotion distance, session 81.62.34.7-1.7-1.8-1.51.51.8-1.6-1.6-1.6-1.81.7-1.5-1.7-1.42.2-0.90.70.30.6
Degree of sensitization distance0.40.42.00.20.3-0.00.0-0.2-0.1-0.20.00.00.1-0.3-0.0-0.4-1.4-0.90.61.41.2
Degree of sensitization stereotypy3.23.57.0-2.5-2.2-2.02.02.3-1.9-1.8-1.9-1.92.1-1.7-1.9-1.62.7-1.01.90.00.4
Conditioned locomotion0.20.31.00.40.30.4-0.4-0.40.40.50.40.4-0.60.50.30.60.20.7-1.0-0.6-0.6
Cocaine response after cond. corrected1.21.83.01.31.61.6-1.6-1.21.41.41.71.6-1.51.11.71.2-1.70.8-0.7-0.8-0.4
Cocaine response after cond. not corrected0.60.91.70.71.01.1-1.1-0.70.91.01.31.1-1.10.81.20.8-0.80.7-0.7-0.9-0.4
Cocaine response before conditioning0.80.92.8-1.2-1.2-1.21.21.1-1.0-0.9-1.0-1.00.7-0.8-1.0-0.71.7-0.30.3-0.30.2
Saline control response1.62.24.7-1.7-1.5-1.31.31.7-1.6-1.4-1.3-1.32.1-1.6-1.2-1.61.1-1.42.20.91.3
Bone: connectivity density0.20.31.2-0.4-0.5-0.80.8-0.2-0.4-0.8-0.6-0.4-0.1-0.1-0.4-0.30.3-0.2-1.10.50.3
Bone: cortical apparent density0.91.42.91.41.41.3-1.3-1.31.21.31.11.1-1.61.10.91.0-1.70.7-0.8-0.6-0.4
Bone: cortical area0.60.93.1-0.6-0.9-1.01.00.5-1.0-1.2-0.8-0.80.4-1.0-0.9-1.10.1-1.20.11.81.3
Bone: cortical porosity0.20.31.8-0.7-0.5-0.30.30.5-0.3-0.3-0.4-0.20.5-0.1-0.2-0.01.30.3-0.3-0.8-0.6
Bone: cortical porosity0.20.31.7-0.6-0.5-0.40.40.5-0.3-0.2-0.5-0.30.5-0.2-0.3-0.11.30.3-0.1-0.8-0.5
Bone: cortical thickness0.30.50.90.80.70.7-0.7-1.00.70.60.80.8-0.90.70.70.7-0.60.6-0.80.0-0.4
Bone: cortical thickness0.00.00.20.1-0.30.0-0.00.2-0.20.00.0-0.0-0.3-0.1-0.1-0.10.50.0-0.20.00.0
Bone: cortical tissue density0.91.42.71.41.41.3-1.3-1.31.31.41.11.1-1.61.21.01.1-1.60.8-0.8-0.7-0.6
Condit. Reinf. active minus inactive responses0.60.71.6-0.5-0.7-0.70.70.6-0.8-0.7-0.9-0.90.9-0.8-0.9-0.9-0.0-1.01.01.31.2
Condit. Reinf. active-inactive response ratio1.61.73.2-1.0-1.1-1.31.30.9-1.3-1.3-1.4-1.31.1-1.3-1.4-1.40.1-1.61.01.81.7
Condit. Reinf. active responses0.10.21.0-0.1-0.2-0.20.20.3-0.2-0.1-0.4-0.30.6-0.3-0.4-0.3-0.2-0.41.00.50.4
Condit. Reinf. inactive responses0.20.20.60.50.40.5-0.5-0.10.50.60.40.4-0.00.50.50.5-0.00.60.3-0.8-0.7
Incentive salience index mean0.60.81.9-0.5-0.7-0.80.80.8-0.8-0.7-1.0-0.91.2-0.9-1.0-0.90.2-0.91.41.11.0
Condit. Reinf. lever presses0.30.51.7-0.4-0.6-0.70.70.8-0.7-0.4-0.8-0.71.0-0.7-0.8-0.60.4-0.61.30.40.4
Condit. Reinf. active minus inactive responses6.29.514.7-3.6-3.2-3.03.03.5-3.3-3.0-2.9-3.03.8-3.3-2.9-3.22.6-2.93.52.02.3
Condit. Reinf. active-inactive response ratio0.81.23.3-1.2-1.1-0.80.81.5-1.1-0.8-0.8-1.11.7-1.1-1.0-1.01.2-0.81.80.60.5
Condit. Reinf. active responses10.515.020.0-4.4-4.0-3.93.94.3-4.1-3.8-3.7-3.74.5-4.2-3.6-4.12.9-3.84.32.93.2
Condit. Reinf. inactive responses5.88.610.7-3.3-3.0-3.13.13.0-3.1-2.9-2.9-2.73.1-3.2-2.6-3.21.7-3.13.22.42.9
Condit. Reinf. lever presses17.825.837.8-6.1-5.6-5.45.45.5-5.5-5.5-5.2-5.15.6-5.3-5.1-5.24.7-4.64.43.13.3
Condit. Reinf. lever reinforcers received11.816.521.9-4.6-4.3-4.14.14.5-4.3-4.0-3.9-3.94.7-4.4-3.8-4.33.2-3.94.52.93.2
Conditioned reinforcement - actives0.20.92.2-1.3-1.1-1.11.10.8-0.9-1.1-0.9-0.91.1-0.7-0.9-0.71.5-0.40.00.30.2
Conditioned reinforcement - inactives0.30.81.30.30.90.9-0.9-1.01.00.91.01.0-0.40.91.01.0-0.50.9-0.1-0.9-1.1
Conditioned locomotion0.40.63.8-1.1-0.8-0.50.50.5-0.5-0.5-0.4-0.50.8-0.1-0.5-0.12.00.5-0.9-0.7-0.9
Patch foraging indifference point 0 sec3.08.511.0-3.3-3.3-3.23.23.0-3.2-3.3-3.2-3.22.9-3.0-3.2-3.02.8-2.61.42.11.8
Patch foraging indifference point AUC0.30.71.7-0.6-0.6-0.70.70.7-0.8-0.8-0.7-0.70.8-0.9-0.7-0.9-0.2-1.11.30.91.0
Delay disc. indifference point, 0s delay1.11.22.2-1.3-1.1-0.90.91.4-1.1-0.9-1.1-1.31.4-1.1-1.3-1.01.0-0.91.50.30.7
Delay disc. indifference point, 16s delay0.10.10.40.00.40.3-0.3-0.40.40.30.40.5-0.20.40.40.4-0.20.4-0.2-0.6-0.5
Delay disc. indifference point, 2s delay1.01.22.3-1.5-1.0-1.01.01.4-1.0-1.0-1.0-1.31.5-1.2-1.2-1.01.0-1.01.10.20.5
Delay disc. indifference point, 24s delay0.60.91.71.11.10.9-0.9-1.11.00.91.21.3-0.81.01.20.9-1.30.7-0.3-0.4-0.3
Delay disc. indifference point, 4s delay1.31.36.9-1.1-0.8-0.50.51.5-0.9-0.5-0.9-1.41.9-1.1-1.2-0.90.6-0.92.60.30.7
Delay disc. indifference point, 8s delay0.20.30.7-0.8-0.5-0.60.60.4-0.5-0.6-0.6-0.60.8-0.5-0.5-0.50.4-0.50.40.20.3
Indifference point function ln k0.20.73.6-1.1-1.0-0.80.80.8-0.7-0.6-0.9-0.80.7-0.4-0.9-0.41.90.2-0.7-0.4-0.5
Indifference point function log k0.20.73.6-1.1-1.0-0.80.80.8-0.7-0.6-0.9-0.80.7-0.4-0.9-0.41.90.2-0.7-0.4-0.5
Patch foraging total patch changes 0 sec2.57.39.7-3.1-3.0-3.03.02.8-2.9-3.0-2.9-2.92.7-2.8-2.9-2.82.6-2.41.41.91.7
Patch foraging total patch changes 12 sec2.93.95.1-1.7-1.9-2.12.11.9-2.1-2.3-2.0-2.01.8-2.1-2.0-2.20.9-2.21.52.22.1
Patch foraging total patch changes 18 sec2.25.26.7-1.9-2.3-2.52.52.3-2.4-2.6-2.5-2.51.9-2.4-2.5-2.51.3-2.41.72.42.2
Patch foraging total patch changes 24 sec0.30.91.7-0.8-0.9-1.01.01.2-1.0-0.9-0.8-1.01.0-1.1-0.8-1.10.5-1.11.30.80.9
Patch foraging total patch changes 6 sec1.32.23.9-2.0-1.6-1.61.61.3-1.6-1.8-1.5-1.51.7-1.4-1.5-1.51.5-1.30.71.10.7
Patch foraging time to switch 0 sec1.97.18.42.92.92.7-2.7-2.92.92.72.82.8-2.82.82.82.8-2.22.6-1.8-2.1-2.2
Patch foraging water rate 0 sec1.35.06.7-2.5-2.6-2.42.42.6-2.5-2.4-2.4-2.42.1-2.4-2.4-2.32.3-1.91.11.51.5
Patch foraging water rate 12 sec0.52.03.9-1.6-1.7-1.61.61.6-1.5-1.5-1.4-1.61.6-1.3-1.4-1.32.0-0.80.90.80.3
Patch foraging water rate 18 sec0.41.01.3-0.9-1.1-1.01.01.1-1.1-1.0-1.0-1.11.0-1.0-1.0-1.00.9-0.81.10.80.7
Patch foraging water rate 24 sec0.40.63.3-1.0-1.0-0.70.70.8-0.7-0.8-0.7-0.70.7-0.4-0.7-0.31.80.2-0.3-0.2-0.4
Patch foraging water rate 6 sec0.30.51.5-0.9-0.9-0.80.80.8-0.7-0.7-0.8-0.70.4-0.5-0.7-0.51.2-0.20.10.2-0.1
Seeking ratio, delayed vs. immediate footshock2.02.93.92.01.71.9-1.9-1.71.81.91.91.8-1.91.81.81.8-1.31.7-1.1-1.2-1.3
Distance traveled before self-admin0.10.30.70.60.70.5-0.5-0.80.60.60.60.4-0.10.60.50.5-0.90.3-0.0-0.3-0.3
Distance traveled after self-admin1.62.74.31.21.51.8-1.8-1.61.71.91.71.7-1.01.91.71.9-0.52.1-1.1-2.0-1.9
Extensor digitorum longus weight0.20.83.80.2-0.2-0.50.50.0-0.5-0.7-0.5-0.40.6-0.7-0.5-0.9-1.2-1.31.11.91.5
Bone: elastic displacement2.02.53.61.51.61.6-1.6-1.91.61.51.61.7-1.81.71.81.6-1.11.5-1.6-1.0-1.6
Bone: elastic work2.22.94.11.61.71.7-1.7-2.01.71.51.71.8-1.91.81.91.8-1.11.7-1.5-1.3-1.8
Bone: endosteal estimation2.04.97.1-1.8-2.0-2.32.32.1-2.3-2.4-2.1-2.21.9-2.4-2.2-2.50.6-2.61.92.72.7
Bone: endosteal perimeter2.66.47.9-2.3-2.5-2.72.72.5-2.6-2.7-2.5-2.52.4-2.7-2.6-2.81.1-2.81.92.72.8
Epididymis fat weight0.10.71.91.41.01.0-1.0-0.70.91.01.10.9-0.50.61.10.7-1.20.30.20.2-0.2
Delta time in closed arm before/after self-admin0.40.32.80.60.70.3-0.3-0.60.40.40.40.30.00.20.30.1-1.7-0.40.60.60.6
Delta time in open arm before/after self-admin2.32.83.5-1.7-1.9-1.81.81.8-1.9-1.8-1.8-1.61.0-1.8-1.6-1.91.2-1.70.61.81.7
Diff in mean of infusions in LGA sessions3.97.08.92.93.02.9-2.9-2.82.92.82.92.8-2.42.82.82.8-2.42.5-1.5-2.2-2.0
Delay discount exponential model param0.10.10.60.40.00.0-0.0-0.30.00.00.10.3-0.60.20.20.1-0.10.1-0.80.30.1
Extinction: sum of active levers before priming0.00.00.40.10.0-0.10.10.0-0.1-0.00.10.10.3-0.20.1-0.1-0.2-0.20.70.10.3
Active lever presses in extinction session 60.70.74.8-1.2-0.8-0.40.40.5-0.4-0.4-0.4-0.40.6-0.1-0.40.12.20.7-1.0-1.3-1.2
Bone: final force0.10.10.9-0.10.00.1-0.1-0.40.0-0.30.10.1-0.70.10.0-0.0-0.2-0.1-1.00.30.2
Bone: final moment0.10.10.4-0.4-0.2-0.20.2-0.2-0.3-0.5-0.2-0.2-0.4-0.2-0.3-0.3-0.1-0.4-0.60.50.4
Food consumed during 24 hour testing period1.63.25.1-2.3-2.0-1.81.82.1-1.8-1.6-1.9-2.12.0-1.6-2.0-1.62.0-1.12.00.11.2
Glucose0.00.00.10.20.20.3-0.3-0.30.20.30.20.1-0.20.10.20.1-0.20.1-0.10.2-0.1
Heart weight0.60.91.7-1.3-1.2-1.01.00.9-1.1-1.1-0.9-0.91.0-0.9-0.8-1.01.1-0.80.20.90.6
Delay discount hyperbolic model param0.10.21.00.50.20.2-0.2-0.50.20.20.30.5-0.80.40.40.3-0.10.4-1.00.1-0.1
Intermittent access intake day 1-15 change0.20.82.3-1.5-1.1-1.11.10.8-0.9-1.1-1.0-0.90.5-0.7-0.9-0.71.5-0.3-0.5-0.2-0.1
Intermittent access intake escalation0.21.02.7-1.6-1.2-1.21.20.9-1.0-1.2-1.1-1.10.7-0.8-1.1-0.81.6-0.4-0.4-0.1-0.1
Intermittent access intake escalation 20.50.91.8-1.3-1.2-1.11.11.0-1.0-1.1-1.1-1.10.5-0.9-1.0-0.91.3-0.6-0.20.30.1
Intermitt. access day 1 inactive lever presses0.22.94.11.71.92.0-2.0-1.71.82.02.01.9-1.61.71.91.7-1.61.5-0.4-1.4-1.4
Intermitt. access day 15 inactive lever presses0.52.73.51.61.71.8-1.8-1.61.71.81.91.8-1.21.81.81.8-1.01.8-0.4-1.6-1.7
Intermitt. access escalation Index0.00.00.1-0.0-0.0-0.00.0-0.10.0-0.00.10.20.20.00.20.0-0.1-0.00.3-0.10.0
Intermittent access day 1 total infusions0.20.71.5-1.2-0.9-0.80.80.7-0.8-0.8-0.9-0.81.2-0.7-0.8-0.70.9-0.61.00.60.3
Intermittent access day 15 total infusions0.51.23.4-1.8-1.3-1.21.20.9-1.1-1.2-1.2-1.11.0-0.9-1.1-0.91.6-0.50.10.10.0
Intermittent access terminal intake (last 3 days)1.11.83.8-1.9-1.6-1.61.61.3-1.5-1.6-1.6-1.51.2-1.2-1.5-1.31.7-0.90.30.70.5
Intermittent access total infusions1.11.32.1-1.4-1.3-1.31.31.0-1.2-1.3-1.3-1.20.9-1.1-1.2-1.21.1-1.00.41.00.7
Intermittent access day 1 locomotion0.00.10.3-0.5-0.3-0.20.2-0.1-0.2-0.2-0.3-0.20.1-0.0-0.2-0.00.50.1-0.30.1-0.3
Intermittent access day 15 total locomotion0.20.72.6-1.3-1.0-1.01.00.6-0.8-1.0-0.9-0.80.6-0.5-0.8-0.51.6-0.1-0.6-0.1-0.4
Intermittent access total locomotion0.40.51.0-1.0-0.8-0.90.90.5-0.7-0.9-0.8-0.70.5-0.5-0.7-0.61.0-0.4-0.10.50.1
Intermittent access standard deviation0.10.71.8-0.6-0.7-0.80.80.8-0.8-0.8-0.8-0.80.6-0.9-0.8-0.90.0-1.01.01.41.0
Left kidney weight0.32.16.1-0.6-0.9-1.11.11.3-1.2-1.1-1.1-1.41.6-1.5-1.2-1.5-0.4-1.92.52.12.1
Right kidney weight0.42.66.3-0.7-1.1-1.31.31.5-1.5-1.4-1.2-1.51.2-1.8-1.3-1.8-0.4-2.22.22.32.5
Cocaine induced anxiety0.51.32.81.71.21.0-1.0-1.41.11.01.11.1-1.51.11.11.1-1.30.8-1.3-0.3-0.5
Post-drug Anxiety1.11.32.41.51.31.1-1.1-1.41.21.11.11.2-1.21.21.21.1-1.50.8-1.0-0.5-0.5
Baseline Anxiety0.20.30.7-0.7-0.4-0.50.50.5-0.5-0.5-0.6-0.50.8-0.5-0.5-0.50.2-0.50.80.30.5
Tail length0.95.013.0-0.8-1.5-1.91.91.8-2.0-1.8-1.8-1.82.2-2.3-1.7-2.4-0.7-3.03.33.63.4
Length with tail0.73.07.4-0.7-1.2-1.41.41.4-1.6-1.4-1.3-1.41.7-1.9-1.3-1.9-0.5-2.32.62.72.6
Length without tail0.10.40.70.40.70.8-0.8-0.40.60.80.80.7-0.60.50.80.6-0.60.40.3-0.6-0.3
Times rat made contact with spout0.20.21.10.60.20.1-0.1-0.10.00.20.0-0.1-0.6-0.10.1-0.2-1.1-0.50.50.60.9
Lifetime Intake1.11.42.4-1.5-1.4-1.41.41.1-1.3-1.4-1.4-1.30.9-1.1-1.3-1.21.3-0.90.40.90.6
Liver weight, left0.10.31.10.40.10.0-0.00.2-0.10.10.10.1-0.3-0.40.2-0.4-1.0-0.70.70.91.0
Liver weight, right0.61.15.31.61.11.0-1.0-0.60.70.90.90.9-1.20.30.90.2-2.3-0.41.10.81.1
Locomotor activity0.91.42.0-1.2-1.4-1.21.21.2-1.3-1.1-1.4-1.41.1-1.2-1.3-1.21.1-1.00.81.01.0
Locomotor testing distance1.63.84.6-1.6-2.1-1.91.92.1-2.1-1.8-2.2-2.11.9-2.1-2.0-2.11.4-1.91.72.11.9
Locomotor testing rearing0.51.84.2-0.4-1.3-1.41.41.4-1.5-1.3-1.4-1.30.6-1.6-1.2-1.60.4-1.71.02.01.6
Locomotion in novel chamber0.30.41.9-1.1-0.8-0.50.50.5-0.6-0.5-0.8-0.71.0-0.3-0.7-0.31.40.1-0.0-0.2-0.3
Locomotion in novel chamber post-restriction0.61.85.4-1.8-1.6-1.51.51.4-1.3-1.5-1.4-1.40.9-1.1-1.4-1.02.3-0.5-0.70.0-0.2
Fecal boli incidents, locomotor time 10.10.21.4-0.8-0.7-0.30.30.4-0.5-0.3-0.4-0.40.5-0.3-0.3-0.31.20.1-0.2-0.20.1
Change in fecal boli incidents, locomotor task0.80.81.51.01.10.9-0.9-0.91.00.81.11.0-0.70.91.20.9-0.90.8-0.6-0.7-0.7
Time >=10cm from walls, locomotor time 10.81.03.2-1.5-1.2-1.01.01.1-1.0-1.0-1.0-0.81.4-0.8-1.0-0.71.8-0.30.2-0.1-0.1
Bouts of movement, locomotor time 10.20.31.9-0.6-0.10.1-0.10.4-0.10.00.1-0.01.4-0.1-0.0-0.10.30.01.4-0.3-0.0
Total resting periods, locomotor time 10.20.20.8-0.40.20.4-0.4-0.10.30.30.60.40.90.30.30.40.30.50.7-0.8-0.5
Rest time, locomotor task time 10.50.81.70.20.81.1-1.1-0.50.91.11.20.90.80.90.91.0-0.11.10.4-1.3-0.8
Distance moved, locomotor task time 10.51.33.4-0.2-0.9-1.31.30.6-1.0-1.3-1.5-1.3-0.8-1.1-1.3-1.2-0.1-1.5-0.21.81.3
Vertical activity count, locomotor time 10.31.83.4-0.8-1.2-1.71.71.0-1.3-1.7-1.7-1.5-0.2-1.4-1.6-1.50.4-1.6-0.31.81.3
Time >=10cm from walls, locomotor time 20.41.12.9-1.3-1.1-0.80.81.4-1.1-0.8-0.7-0.91.7-1.1-0.9-1.01.1-0.81.20.30.9
Bouts of movement, locomotor time 20.20.81.6-0.9-0.8-0.80.81.0-0.8-0.9-0.7-1.11.2-1.0-0.7-0.90.6-0.91.30.40.4
Total resting periods, locomotor time 20.10.31.0-0.6-0.4-0.50.50.7-0.5-0.5-0.4-0.90.9-0.6-0.4-0.60.4-0.61.00.10.1
Rest time, locomotor task time 21.42.43.31.71.81.7-1.7-1.71.81.71.71.5-1.51.71.61.6-1.71.4-1.1-1.1-0.9
Distance moved, locomotor task time 22.43.14.0-1.7-2.0-1.81.82.0-2.0-1.9-2.0-1.81.3-2.0-1.9-1.91.6-1.71.11.51.4
Vertical activity count, locomotor time 21.12.53.7-1.2-1.6-1.81.81.6-1.7-1.9-1.8-1.61.1-1.7-1.8-1.81.0-1.70.71.71.4
Light reinforcement 10.41.93.41.51.61.5-1.5-1.51.51.51.51.5-1.31.31.51.3-1.80.9-0.3-0.7-0.5
Light reinforcement 20.10.20.7-0.20.40.5-0.5-0.40.40.60.50.50.30.50.60.5-0.10.60.2-0.8-0.5
Bone: marrow area1.84.36.7-1.6-1.9-2.22.21.9-2.1-2.2-2.0-2.01.8-2.3-2.0-2.30.5-2.51.72.62.6
Bone: maximum diameter2.65.26.8-2.2-2.3-2.52.52.0-2.4-2.6-2.2-2.22.1-2.4-2.3-2.51.2-2.51.32.62.5
Bone: maximum force0.10.20.7-0.5-0.3-0.40.4-0.2-0.3-0.7-0.2-0.2-0.3-0.3-0.3-0.30.0-0.4-0.80.40.4
Bone: maximum moment0.20.30.8-0.7-0.6-0.60.60.1-0.6-0.9-0.5-0.5-0.0-0.5-0.6-0.60.1-0.6-0.50.70.7
Mean time between licks in bursts1.27.410.0-2.6-2.6-2.52.53.1-2.8-2.5-2.6-2.82.8-3.1-2.7-3.01.2-3.13.22.13.1
Mean num. licks in bursts1.74.56.0-2.4-2.5-2.32.32.3-2.3-2.2-2.3-2.32.4-2.1-2.4-2.12.4-1.61.31.51.3
Cd content in liver0.10.10.70.80.40.3-0.3-0.20.20.20.40.2-0.20.10.20.1-0.8-0.20.10.60.3
Co content in liver1.61.92.8-0.8-1.3-1.51.51.6-1.4-1.3-1.5-1.51.0-1.5-1.7-1.50.7-1.51.41.61.3
Cu content in liver0.80.94.8-0.2-0.5-0.50.51.2-0.7-0.2-0.5-0.61.2-1.0-0.7-0.9-0.2-1.12.21.21.3
Fe content in liver0.10.10.20.20.30.5-0.5-0.20.30.40.40.3-0.30.20.40.3-0.20.2-0.3-0.1-0.2
K content in liver0.00.00.30.10.20.0-0.00.20.10.2-0.10.00.2-0.1-0.0-0.0-0.4-0.10.50.00.3
Mg content in liver0.10.10.2-0.2-0.2-0.20.20.5-0.2-0.1-0.2-0.30.1-0.2-0.3-0.20.5-0.1-0.1-0.20.0
Mn content in liver2.12.33.61.11.31.5-1.5-1.41.51.51.51.4-1.71.61.41.7-0.31.8-1.8-1.9-1.7
Na content in liver0.30.41.1-0.8-0.7-0.50.50.8-0.6-0.4-0.7-0.70.3-0.6-0.8-0.51.0-0.2-0.4-0.30.1
Rb content in liver0.70.81.4-0.5-1.0-1.01.00.8-1.0-0.9-1.2-0.90.5-0.9-0.9-0.90.5-0.90.41.20.8
Se content in liver7.18.411.82.83.13.4-3.4-2.83.23.13.33.0-2.43.13.03.1-2.12.9-1.7-2.7-2.3
Sr content in liver0.10.10.70.0-0.2-0.10.10.1-0.1-0.2-0.1-0.3-0.50.0-0.30.00.60.2-0.8-0.1-0.4
Zn content in liver3.23.75.8-1.7-1.9-1.91.92.4-2.0-1.8-1.9-2.02.2-2.1-1.9-2.01.4-1.92.21.61.8
Bone: minimum diameter1.22.46.4-0.7-1.1-1.41.41.1-1.4-1.4-1.2-1.41.1-1.7-1.4-1.7-0.6-2.11.72.52.4
Time in familiar zone, hab. session 10.00.10.30.30.2-0.10.1-0.10.00.1-0.1-0.2-0.3-0.0-0.3-0.1-0.5-0.20.2-0.10.4
Time in novel zone, hab. session 10.10.10.30.20.20.3-0.3-0.30.20.10.30.4-0.10.20.50.2-0.30.1-0.20.4-0.2
Total zone transitions, hab. session 10.10.10.5-0.4-0.1-0.20.2-0.10.0-0.1-0.1-0.20.00.2-0.20.20.70.4-0.6-0.7-0.7
Total locomotion distance, hab. session 10.30.42.01.10.70.5-0.5-0.30.40.60.60.6-0.70.10.60.1-1.4-0.30.20.50.6
Locomotion velocity, hab. session 10.10.21.00.80.40.3-0.3-0.10.20.40.40.4-0.50.00.40.0-1.0-0.30.10.50.6
Time in familiar zone, hab. session 22.22.53.8-1.4-1.6-1.81.81.2-1.7-1.6-1.9-1.81.3-1.6-1.8-1.70.8-1.71.31.51.6
Time in novel zone, hab. session 21.21.32.20.91.01.4-1.4-0.61.11.21.51.4-0.91.11.31.2-0.21.3-0.7-1.1-1.3
Total zone transitions, hab. session 20.81.03.4-1.5-1.1-0.90.91.2-0.9-1.0-0.8-1.01.3-0.7-0.9-0.61.8-0.10.5-0.7-0.3
Total locomotion distance, hab. session 20.30.42.0-0.1-0.2-0.10.10.7-0.4-0.2-0.1-0.20.8-0.6-0.2-0.6-0.6-0.91.40.61.2
Locomotion velocity, hab. session 20.30.41.90.1-0.00.0-0.00.6-0.3-0.00.1-0.10.6-0.6-0.0-0.5-0.8-0.81.40.71.2
Novel to familiar place preference ratio0.00.00.1-0.20.00.1-0.10.20.10.00.30.40.30.00.40.10.30.2-0.1-0.3-0.2
Novelty place preference0.10.10.30.00.10.2-0.20.20.10.10.40.50.20.10.50.20.20.3-0.0-0.4-0.2
Time in novel zone, NPP test0.00.10.2-0.2-0.10.0-0.00.4-0.1-0.10.20.20.4-0.10.30.00.50.10.2-0.3-0.2
Total zone transitions, NPP test0.10.21.2-0.5-0.10.2-0.20.20.10.20.30.10.30.20.00.20.70.50.3-1.1-0.5
Total locomotion distance, NPP test0.50.71.50.90.91.2-1.2-0.20.71.11.20.9-0.10.41.00.5-1.20.21.2-0.40.3
Locomotion velocity, NPP test0.91.32.71.31.31.6-1.6-0.51.11.51.61.3-0.50.71.40.8-1.50.50.9-0.60.1
Intraocular pressure0.20.31.4-0.6-0.5-0.30.30.1-0.2-0.4-0.3-0.4-0.1-0.0-0.2-0.01.20.3-0.9-0.4-0.9
Delta distance traveled before/after self-admin0.20.21.4-0.6-0.3-0.00.00.2-0.10.0-0.10.00.40.2-0.10.21.20.6-0.4-0.9-0.7
Delta ambulatory time before/after self-admin0.20.31.5-0.6-0.20.0-0.00.20.00.10.00.10.50.3-0.00.31.20.8-0.3-1.0-0.9
Parametrial fat weight0.20.51.70.60.90.8-0.8-1.00.70.60.90.8-0.40.60.90.5-1.30.2-0.2-0.1-0.1
Pavlov. Cond. lever latency1.92.43.71.31.61.7-1.7-1.61.61.41.91.9-1.41.61.81.6-1.11.5-1.7-1.0-1.3
Pavlov. Cond. magazine entry latency4.05.16.5-2.2-2.5-2.42.42.5-2.5-2.4-2.5-2.52.0-2.4-2.5-2.41.8-2.21.51.81.9
Pavlov. Cond. change in total contacts1.11.22.0-1.1-1.2-0.90.91.4-1.2-0.9-1.2-1.31.3-1.2-1.2-1.11.0-1.01.30.41.0
Pavlov. Cond. index score3.74.76.3-1.8-2.3-2.32.32.3-2.3-2.1-2.5-2.52.0-2.3-2.4-2.31.5-2.11.91.71.9
Pavlov. Cond. latency score3.54.56.1-1.8-2.3-2.32.32.3-2.3-2.1-2.5-2.41.9-2.2-2.4-2.21.6-2.11.71.61.9
Pavlov. Cond. lever contacts1.92.33.3-1.1-1.5-1.61.61.6-1.6-1.3-1.8-1.81.5-1.6-1.7-1.60.9-1.51.81.11.3
Pavlov. Cond. magazine entry number4.15.26.72.12.52.4-2.4-2.52.52.32.52.6-2.22.42.52.4-1.82.2-1.8-1.8-1.8
Pavlov. Cond. intertrial magazine entries2.12.63.71.71.81.8-1.8-1.51.81.91.91.8-1.21.71.91.7-1.21.6-0.4-1.2-1.2
Pavlov. Cond. lever-magazine prob. diff.3.03.85.1-1.6-2.0-2.12.12.0-2.1-1.9-2.3-2.21.7-2.1-2.2-2.11.3-1.91.71.61.8
Pavlov. Cond. response bias2.02.53.4-1.3-1.6-1.61.61.7-1.7-1.5-1.8-1.81.6-1.6-1.8-1.61.0-1.51.81.21.4
Pavlov. Cond. lever latency18.926.540.26.35.75.5-5.5-5.75.55.55.35.1-5.85.35.25.2-5.24.4-4.4-2.7-2.9
Pavlov. Cond. magazine entry latency3.75.28.1-2.8-2.7-2.72.72.5-2.5-2.8-2.5-2.31.9-2.2-2.5-2.22.8-1.70.31.00.9
Pavlov. Cond. change in total contacts7.117.325.6-5.1-4.7-4.34.34.9-4.5-4.4-4.1-4.24.8-4.3-4.1-4.14.5-3.43.52.12.1
Pavlov. Cond. index score12.119.127.4-5.2-4.9-4.84.84.9-4.7-4.8-4.5-4.54.7-4.5-4.5-4.44.6-3.72.92.32.3
Pavlov. Cond. latency score10.216.424.2-4.9-4.6-4.54.54.6-4.4-4.5-4.2-4.14.3-4.1-4.2-4.04.4-3.32.62.02.0
Pavlov. Cond. lever contacts17.325.538.1-6.2-5.6-5.45.45.6-5.4-5.4-5.2-4.95.8-5.2-5.1-5.15.0-4.34.32.82.9
Pavlov. Cond. magazine entry number6.17.912.93.33.33.1-3.1-3.33.13.22.92.9-3.02.82.92.7-3.62.0-1.3-1.3-1.0
Pavlov. Cond. intertrial magazine entries0.30.62.7-0.2-0.2-0.30.30.4-0.5-0.1-0.4-0.40.6-0.7-0.3-0.8-0.9-1.11.61.31.6
Pavlov. Cond. lever-magazine prob. diff.11.617.825.4-5.0-4.8-4.64.64.8-4.6-4.7-4.4-4.34.5-4.4-4.4-4.34.4-3.62.92.32.3
Pavlov. Cond. response bias18.826.037.4-6.1-5.7-5.55.55.6-5.5-5.5-5.3-5.15.7-5.2-5.2-5.15.2-4.33.92.92.8
Time in closed arm before self-admin0.30.42.7-0.8-0.9-0.50.50.7-0.6-0.5-0.6-0.60.7-0.3-0.5-0.31.60.2-0.1-0.4-0.4
Time in closed arm after self-admin1.11.31.90.91.11.2-1.2-1.21.21.21.11.1-0.61.41.11.3-0.61.4-0.4-1.3-1.3
Time in open arm before self-admin1.51.93.21.41.81.5-1.5-1.51.61.61.51.4-0.81.41.41.5-1.61.1-0.3-1.1-1.0
Time in open arm after self-admin1.01.12.7-0.7-0.9-1.21.20.9-1.1-1.1-1.1-1.00.5-1.2-1.0-1.30.1-1.50.41.71.3
Bone: periosteal estimation1.63.87.2-1.5-1.8-2.02.01.7-2.0-2.2-1.8-1.81.4-2.1-1.9-2.20.5-2.41.32.72.4
Bone: periosteal perimeter2.24.36.5-1.9-2.0-2.22.21.9-2.2-2.1-2.1-2.02.0-2.2-2.1-2.30.7-2.41.72.52.5
Bone: post-yield work0.40.71.3-0.8-0.7-1.11.10.2-0.8-1.1-0.9-1.00.4-0.7-1.1-0.90.1-1.0-0.40.91.0
Progressive ratio test 1 active lever presses0.20.40.90.20.60.5-0.5-0.80.70.50.50.6-0.60.80.60.8-0.00.8-1.0-0.7-0.9
Progressive ratio test 1 breakpoint0.20.40.90.20.60.5-0.5-0.80.70.50.50.6-0.60.80.60.7-0.10.8-0.9-0.7-1.0
Progressive ratio test 1 inactive lever presses0.20.51.00.40.70.6-0.6-1.00.70.60.70.8-0.80.80.80.8-0.40.8-0.5-0.6-1.0
Progressive ratio test 2 active lever presses0.40.50.8-0.9-0.7-0.90.90.5-0.7-0.9-0.8-0.80.7-0.6-0.7-0.70.6-0.60.10.70.4
Progressive ratio test 2 breakpoint0.40.50.8-0.9-0.7-0.90.90.5-0.7-0.9-0.8-0.80.7-0.6-0.7-0.70.6-0.60.10.70.4
Progressive ratio test 2 inactive lever presses0.00.10.3-0.5-0.4-0.50.50.1-0.3-0.5-0.3-0.20.6-0.2-0.2-0.30.5-0.20.20.5-0.2
Incentive Sensitization - Responses0.71.92.6-1.4-1.4-1.61.61.3-1.4-1.6-1.5-1.41.6-1.4-1.4-1.41.0-1.30.91.31.0
Incentive Sensitization - Breakpoint0.71.72.3-1.4-1.3-1.51.51.2-1.3-1.5-1.4-1.31.5-1.3-1.3-1.31.0-1.20.71.20.9
Sum of active levers in priming session hrs 5-60.10.10.30.0-0.10.2-0.20.2-0.0-0.00.30.20.4-0.00.10.00.30.10.6-0.4-0.2
Progressive ratio0.10.20.9-0.4-0.6-0.30.30.4-0.4-0.4-0.4-0.2-0.3-0.3-0.3-0.30.9-0.0-0.4-0.2-0.1
Food seeking constrained by brief footshock2.12.63.3-1.7-1.6-1.61.61.8-1.7-1.6-1.5-1.71.5-1.8-1.4-1.81.0-1.81.31.41.8
Seeking ratio, punishment vs. effort0.61.33.1-0.9-0.8-1.11.11.1-1.1-1.0-1.0-1.21.2-1.3-0.9-1.3-0.1-1.51.21.51.7
Retroperitoneal fat weight0.72.916.02.61.91.4-1.4-1.51.21.21.51.5-1.30.51.60.4-4.0-0.80.62.31.6
Reaction time number correct0.10.31.5-0.5-0.00.2-0.2-0.10.20.30.20.20.30.40.30.50.90.8-0.4-1.2-0.9
Reaction time mean minus median0.31.72.2-1.3-1.4-1.41.41.3-1.4-1.4-1.4-1.40.9-1.4-1.4-1.50.7-1.50.81.31.4
Reaction time mean minus median AUC0.21.52.0-1.4-1.4-1.31.31.3-1.4-1.3-1.3-1.20.9-1.3-1.2-1.31.1-1.20.60.91.1
Reaction time num false alarms0.91.53.41.71.51.2-1.2-1.31.31.21.31.6-1.41.11.41.0-1.90.6-0.3-0.3-0.1
Reaction time num false alarms AUC0.41.01.81.31.21.0-1.0-1.01.11.01.11.3-1.10.91.20.9-1.30.7-0.2-0.5-0.2
Reaction time trials correct on left0.10.31.5-0.5-0.00.2-0.2-0.10.20.30.20.20.30.40.30.50.90.8-0.4-1.2-0.9
Reaction time trials on left0.10.31.6-0.5-0.00.2-0.2-0.10.20.30.20.20.30.40.30.50.90.8-0.4-1.3-0.9
Reaction time mean0.30.61.90.80.80.7-0.7-0.80.60.50.80.7-1.30.40.70.4-1.4-0.0-0.90.30.2
Reaction time mean AUC0.51.22.61.21.21.1-1.1-1.21.01.01.31.2-1.60.91.20.8-1.60.5-1.1-0.2-0.2
Median of all reaction times1.01.53.21.41.31.3-1.3-1.31.21.01.41.3-1.81.01.30.9-1.70.5-1.4-0.2-0.2
Reaction time omissions0.00.10.2-0.2-0.0-0.10.10.1-0.1-0.10.10.1-0.0-0.30.1-0.3-0.4-0.50.40.30.5
Reaction time false alarm rate0.91.23.11.61.31.1-1.1-1.11.10.91.21.3-1.50.81.20.8-1.80.4-0.3-0.00.0
Reaction time premature initiation rate2.94.58.5-1.5-1.9-2.22.21.9-2.2-2.3-2.1-2.21.3-2.4-2.0-2.50.4-2.71.22.92.7
Reaction time premature initiations1.13.24.2-1.7-1.9-2.02.01.7-2.0-2.1-1.9-1.91.3-2.0-1.8-2.00.9-2.00.72.02.0
Std. dev. reaction times0.30.92.3-0.5-0.8-0.90.90.8-1.0-1.0-0.8-0.80.2-1.1-0.8-1.2-0.2-1.40.41.51.5
Reaction time trials completed0.10.31.6-0.5-0.00.2-0.2-0.10.20.30.20.20.30.40.30.50.90.8-0.4-1.3-0.9
Reaction time trials AUC0.10.21.1-0.6-0.10.1-0.10.10.10.20.10.20.40.30.20.30.80.7-0.2-1.0-0.7
Run reversals in cocaine runway, females0.80.93.80.5-0.0-0.50.50.1-0.4-0.5-0.5-0.5-0.1-0.8-0.5-0.9-1.6-1.50.81.91.9
Run reversals in cocaine runway, males0.10.10.60.10.30.2-0.2-0.40.30.20.0-0.1-0.60.30.00.2-0.30.2-0.8-0.2-0.1
Latency to leave start box in cocaine runway1.82.54.01.92.01.8-1.8-1.51.71.71.71.7-1.91.41.61.5-2.01.0-0.9-1.1-0.8
Latency to leave start box in cocaine runway, F1.41.84.81.71.81.6-1.6-1.21.41.51.41.3-1.51.01.31.0-2.20.5-0.3-0.7-0.1
Latency to leave start box in cocaine runway, M0.70.71.00.70.80.7-0.7-0.80.80.70.80.8-0.90.90.80.9-0.30.9-0.9-0.9-1.0
Std. dev. time between licks in bursts1.42.75.1-1.2-1.3-1.51.51.8-1.6-1.4-1.7-1.61.3-1.9-1.6-1.90.2-2.12.11.42.3
Total sessions with >9 infusions1.51.92.8-1.5-1.6-1.61.61.5-1.5-1.6-1.7-1.60.6-1.4-1.6-1.41.5-1.20.10.80.8
Short access day 1 total inactive lever presses0.00.00.1-0.00.20.2-0.2-0.20.20.20.20.3-0.30.20.20.2-0.20.20.1-0.1-0.3
Short access day 10 total inactive lever presses0.21.52.01.31.31.4-1.4-1.21.31.41.41.3-0.81.31.31.3-1.01.2-0.2-0.8-1.2
Short access day 1 total infusions1.83.64.4-2.0-2.0-2.12.12.0-2.1-2.1-2.1-2.01.5-2.1-2.0-2.01.6-1.91.31.61.5
Short access day 10 total infusions0.71.11.5-1.2-1.2-1.21.21.2-1.2-1.2-1.1-1.00.9-1.1-1.0-1.11.1-1.00.70.80.8
Short access total infusions1.31.82.9-1.7-1.5-1.51.51.4-1.4-1.5-1.5-1.41.2-1.4-1.4-1.31.4-1.10.70.80.8
Short access day 1 locomotion1.11.94.3-1.9-1.7-1.61.61.3-1.5-1.6-1.5-1.60.8-1.3-1.6-1.22.1-0.8-0.40.40.2
Short access day 10 total locomotion0.41.62.3-1.3-1.5-1.41.41.4-1.4-1.4-1.4-1.50.8-1.3-1.5-1.31.5-1.00.20.90.6
Short access total locomotion0.40.51.4-0.9-0.9-0.80.80.6-0.7-0.8-0.8-0.9-0.1-0.6-0.9-0.61.2-0.3-1.00.20.1
One hour access (0.3 mA shock)0.91.01.8-1.1-1.3-1.21.21.0-1.1-1.2-1.1-1.10.6-1.0-1.1-1.01.3-0.7-0.20.90.5
Compulsive drug intake0.71.12.60.50.81.0-1.0-0.81.01.01.11.0-0.61.11.01.20.31.4-1.3-1.6-1.3
One hour access (shock baseline)0.61.52.2-1.3-1.5-1.41.41.3-1.4-1.4-1.4-1.40.8-1.2-1.4-1.21.4-1.00.20.90.7
Social response proportion0.40.51.21.00.80.8-0.8-0.60.70.70.80.7-1.10.50.80.5-1.10.3-0.4-0.40.1
Social responses0.30.31.71.00.60.5-0.5-0.20.30.50.40.4-0.90.10.40.1-1.3-0.30.40.40.8
Social time3.75.77.52.52.42.7-2.7-2.12.52.72.72.6-2.42.42.62.5-1.62.3-1.9-2.0-1.9
Soleus weight0.41.34.80.3-0.1-0.70.70.2-0.6-0.7-0.5-0.40.3-1.0-0.4-1.1-1.8-1.81.72.22.1
Bone: stiffness0.20.31.10.10.60.5-0.5-0.80.50.20.60.6-0.80.40.50.3-1.00.0-1.1-0.20.3
Tibialis anterior weight0.20.81.9-0.7-0.7-0.80.80.6-0.8-0.9-0.7-0.71.1-1.0-0.7-1.0-0.2-1.21.41.41.0
Time to tail flick, vehicle, before self-admin0.30.40.8-0.0-0.7-0.80.80.4-0.7-0.9-0.7-0.7-0.4-0.5-0.6-0.60.4-0.5-0.50.90.6
Time to tail flick, vehicle, after self-admin0.71.41.9-1.4-1.4-1.21.21.2-1.3-1.3-1.3-1.21.1-1.2-1.3-1.21.1-1.10.41.11.0
Time to tail flick, test, before self-admin0.80.92.2-0.6-0.7-0.90.90.7-0.9-0.8-1.0-1.00.9-1.0-1.0-1.0-0.2-1.31.21.51.3
Time to tail flick, test, after self-admin0.40.52.8-0.1-0.3-0.40.40.6-0.5-0.3-0.5-0.50.9-0.7-0.5-0.6-0.3-0.81.71.00.7
Delta time to tail flick, vehicle, before/after SA0.50.51.6-1.3-0.7-0.60.60.8-0.6-0.6-0.7-0.71.2-0.7-0.7-0.60.9-0.50.20.00.2
Delta time to tail flick, test, before/after SA0.60.71.10.80.80.9-0.9-0.60.90.91.00.9-0.50.80.90.9-0.40.9-0.0-1.0-1.0
Tibia length0.82.37.9-1.9-1.9-1.71.71.7-1.6-1.7-1.4-1.51.1-1.3-1.6-1.22.8-0.50.20.3-0.4
Ambulatory time before self-admin0.41.11.50.91.11.1-1.1-1.21.21.11.11.0-0.71.21.11.2-0.71.1-0.5-1.1-1.2
Ambulatory time after self-admin1.72.85.31.01.41.7-1.7-1.51.71.81.71.7-0.71.91.72.00.02.3-0.9-2.3-2.3
Bone: tissue strength1.01.02.70.30.70.8-0.8-1.10.90.70.90.7-0.81.10.71.10.31.3-1.7-1.3-1.6
Total heroin consumption0.00.00.20.10.00.0-0.00.20.00.0-0.00.10.4-0.00.00.00.10.10.5-0.20.1
Bone: trabecular number0.61.23.21.11.00.7-0.7-1.71.10.70.81.0-1.41.31.01.1-1.01.0-1.8-0.3-0.5
Bone: trabecular spacing0.40.61.8-1.2-0.8-0.60.61.1-0.7-0.5-0.7-0.81.2-0.7-0.8-0.51.4-0.20.9-0.2-0.1
Bone: trabecular thickness0.20.21.10.70.40.3-0.3-0.70.30.30.30.4-0.20.20.30.1-1.0-0.2-0.00.90.3
Bone: trabecular tissue density0.71.23.81.21.41.4-1.4-1.21.21.31.31.2-0.80.81.00.8-1.90.30.1-0.20.1
Water consumed over 24 hours0.30.61.21.10.90.7-0.7-0.90.80.80.70.7-1.00.80.80.8-0.90.70.3-0.5-0.4
Number of responses in last shaping day0.20.31.30.90.30.1-0.1-0.20.10.10.10.1-0.4-0.10.1-0.2-1.2-0.50.61.10.9