Map6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Map6 0.2 0.11 4.2e-15 0.16 0.16 0.17 0.17 2.3e-14 4.6e-15 7.4e-16 2.4e-15
2 Brain isoform ratio NM_001398600.1 0.03 0.02 6.6e-03 0.01 0.02 0.01 0.01 1.6e-02 2.7e-03 1.5e-02 2.1e-02
3 Liver intron excision ratio chr1_162982454_163017059 0.04 0.03 1.8e-04 0.03 0.02 0.02 0.02 3.1e-04 9.0e-04 3.0e-03 2.7e-03
4 Liver intron excision ratio chr1_162982454_163026215 0.04 0.03 1.5e-04 0.03 0.03 0.02 0.02 3.0e-04 6.2e-04 2.7e-03 2.9e-03
5 Brain mRNA stability Map6 0.13 0.08 1.9e-09 0.1 0.09 0.07 0.09 2.9e-09 8.0e-09 2.8e-07 7.1e-09
6 Brain alternative polyA NM_001398600.1 0.03 0.02 4.9e-03 0.02 0.02 0.01 0.01 1.1e-02 3.2e-03 2.6e-02 1.4e-02
7 Liver alternative polyA NM_001398602.1 0.05 0.04 2.1e-05 0.04 0.03 0.03 0.03 8.6e-05 2.5e-04 1.9e-04 1.9e-04
8 NAcc gene expression Map6 0.3 0.13 0.0e+00 0.22 0.22 0.22 0.22 1.9e-33 1.5e-32 4.4e-32 2.1e-33
9 Adipose alternative polyA NM_001398602.1 0.08 0.05 2.2e-08 0.07 0.07 0.07 0.07 2.1e-08 6.0e-08 8.7e-08 2.3e-08
10 PL isoform ratio NM_001398600.1 0.03 0.02 3.7e-03 0.02 0.01 0.01 0.01 3.7e-03 1.0e-02 8.4e-03 1.3e-02
11 NAcc alternative polyA NM_001398600.1 0.04 0.03 6.9e-07 0.04 0.04 0.04 0.03 3.3e-06 9.3e-07 3.0e-06 6.6e-06
12 IC gene expression Map6 0.2 0.12 8.4e-07 0.17 0.14 0.14 0.14 1.4e-07 1.2e-06 2.8e-06 1.3e-06
13 NAcc isoform ratio NM_001398600.1 0.04 0.03 5.2e-07 0.04 0.04 0.04 0.04 1.7e-06 4.1e-07 7.0e-07 1.7e-06
14 Adipose mRNA stability Map6 0.07 0.04 1.8e-05 0.03 0.04 0.03 0.03 2.5e-04 4.2e-05 4.2e-04 2.0e-04
15 pVTA alternative polyA NM_001398600.1 0.04 0.03 7.0e-04 0.02 0.04 0.03 0.03 8.1e-03 7.4e-04 1.9e-03 3.3e-03
16 OFC isoform ratio NM_001398600.1 0.19 0.14 2.4e-03 0.01 0.07 0.1 0.04 2.0e-01 8.1e-03 2.2e-03 3.2e-02
17 pVTA mRNA stability Map6 0.04 0.03 2.8e-03 0.03 0.03 0.04 0.03 1.7e-03 1.5e-03 7.9e-04 1.6e-03
18 PL gene expression Map6 0.07 0.04 2.8e-09 0.08 0.08 0.08 0.08 7.1e-09 6.9e-09 1.2e-08 4.2e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.10.10.7-0.30.20.1-0.10.70.20.10.1-0.10.60.3-0.00.2-0.40.10.8-0.50.2
Area under the delay curve0.10.10.50.5-0.00.1-0.1-0.2-0.10.10.20.3-0.6-0.20.2-0.10.1-0.2-0.70.3-0.1
BMI with tail0.20.73.7-0.5-0.20.4-0.4-0.5-0.50.50.20.4-0.3-0.90.3-0.9-1.0-1.3-0.9-1.91.6
BMI without tail1.02.910.30.1-1.11.4-1.4-1.3-1.51.41.31.3-1.3-1.81.2-1.9-0.7-2.4-2.0-3.22.7
Body weight0.52.47.90.2-0.81.0-1.0-1.1-1.21.10.81.0-1.2-1.70.8-1.7-1.1-2.3-2.2-2.82.7
Weight adjusted by age0.50.82.90.5-0.70.7-0.7-0.8-0.80.80.80.8-1.4-0.90.8-0.90.1-1.0-1.7-1.10.8
Bone surface1.52.84.51.7-1.72.0-2.0-1.2-1.82.11.81.8-1.3-1.61.7-1.80.8-1.7-0.4-1.91.8
Bone volume0.81.43.00.9-1.21.4-1.4-0.7-1.21.41.31.3-0.8-1.11.3-1.20.4-1.3-0.2-1.71.6
Breakpoint value in progressive ratio session1.21.42.0-1.11.2-1.21.21.21.3-1.1-1.2-1.21.01.3-1.21.3-0.51.31.01.4-1.3
Number of licking bursts2.94.87.5-2.72.5-2.42.42.42.3-2.3-2.3-2.22.72.0-2.52.0-2.71.41.11.1-1.0
Context. condit. distance diff. score2.12.64.71.8-1.91.8-1.8-1.4-1.72.01.82.0-1.6-1.41.9-1.42.2-1.00.4-0.90.6
Locomotion velocity, session 10.91.03.1-0.80.8-1.01.00.61.0-1.2-1.0-0.80.91.1-0.91.10.11.40.61.8-1.2
Locomotion distance, session 10.20.31.90.7-0.60.2-0.2-0.9-0.40.10.10.3-0.7-0.30.1-0.11.40.3-0.20.9-0.3
Locomotion velocity, session 20.10.11.3-0.0-0.10.1-0.1-0.4-0.10.00.2-0.1-0.1-0.2-0.1-0.10.1-0.1-1.10.3-0.1
Locomotion distance, session 20.20.31.20.4-0.60.4-0.4-0.8-0.50.30.50.5-0.6-0.40.5-0.40.9-0.1-1.10.2-0.1
Locomotion velocity, session 30.20.21.60.3-0.60.2-0.2-0.6-0.40.40.30.4-0.5-0.20.3-0.11.30.20.00.2-0.5
Locomotion distance, session 30.40.42.70.6-0.70.4-0.4-0.7-0.50.40.50.6-0.2-0.20.6-0.21.60.30.40.7-0.7
Stereotopy head waving bouts, day 30.20.21.0-0.60.6-0.40.40.40.4-0.5-0.3-0.40.40.2-0.40.2-1.0-0.0-0.0-0.00.4
Stereotopy head waving duration, day 30.20.20.40.6-0.50.5-0.5-0.3-0.50.50.60.6-0.7-0.40.6-0.40.5-0.3-0.3-0.40.0
Locomotion velocity, session 70.40.51.1-0.70.5-0.70.70.60.6-0.6-0.7-0.70.60.7-0.60.7-0.10.80.90.5-1.0
Locomotion distance, session 70.10.10.5-0.50.3-0.30.30.40.3-0.2-0.3-0.10.50.3-0.20.3-0.20.20.7-0.1-0.4
Stereotopy head waving bouts, day 71.41.63.41.7-1.51.4-1.4-1.5-1.31.21.31.3-1.4-1.11.4-1.11.8-0.7-1.20.00.2
Stereotopy head waving duration, day 72.32.84.22.0-1.91.8-1.8-1.9-1.81.71.71.7-2.0-1.61.7-1.61.9-1.2-1.7-0.70.8
Locomotion velocity, session 81.31.52.61.6-1.41.5-1.5-1.0-1.31.51.41.5-1.0-1.21.4-1.21.2-1.0-0.1-0.60.9
Locomotion distance, session 81.62.34.71.7-1.81.5-1.5-1.8-1.61.61.61.8-1.7-1.51.7-1.42.2-0.9-0.7-0.30.5
Degree of sensitization distance0.40.42.0-0.30.30.0-0.00.2-0.10.2-0.0-0.0-0.1-0.30.0-0.4-1.4-0.9-0.6-1.41.2
Degree of sensitization stereotypy3.33.57.02.5-2.22.0-2.0-2.3-1.91.81.91.9-2.1-1.71.9-1.62.7-1.0-1.9-0.00.4
Conditioned locomotion0.20.31.0-0.40.3-0.40.40.40.4-0.5-0.4-0.40.60.5-0.30.60.20.71.00.6-0.6
Cocaine response after cond. corrected1.51.83.0-1.31.6-1.61.61.21.4-1.4-1.7-1.61.51.1-1.71.2-1.70.80.70.8-0.4
Cocaine response after cond. not corrected0.80.91.7-0.71.0-1.11.10.70.9-1.0-1.3-1.11.10.8-1.20.8-0.80.70.70.9-0.4
Cocaine response before conditioning0.80.92.81.2-1.21.2-1.2-1.1-1.00.91.01.0-0.7-0.81.0-0.71.7-0.3-0.30.30.2
Saline control response1.72.24.71.7-1.51.3-1.3-1.7-1.61.41.31.3-2.1-1.61.2-1.61.1-1.4-2.2-0.91.3
Bone: connectivity density0.20.31.20.4-0.50.8-0.80.2-0.40.80.60.40.1-0.10.4-0.30.3-0.21.1-0.50.3
Bone: cortical apparent density1.01.42.9-1.41.4-1.31.31.31.2-1.3-1.1-1.11.61.1-0.91.0-1.70.70.80.6-0.4
Bone: cortical area0.60.93.10.6-0.91.0-1.0-0.5-1.01.20.80.8-0.4-1.00.9-1.10.1-1.2-0.1-1.81.3
Bone: cortical porosity0.20.31.80.7-0.50.3-0.3-0.5-0.30.30.40.2-0.5-0.10.2-0.01.30.30.30.8-0.6
Bone: cortical porosity0.20.31.70.6-0.50.4-0.4-0.5-0.30.20.50.3-0.5-0.20.3-0.11.30.30.10.8-0.5
Bone: cortical thickness0.30.50.9-0.80.7-0.70.71.00.7-0.6-0.8-0.80.90.7-0.70.7-0.60.60.8-0.0-0.4
Bone: cortical thickness0.00.00.2-0.1-0.3-0.00.0-0.2-0.2-0.0-0.00.00.3-0.10.1-0.10.50.00.2-0.00.0
Bone: cortical tissue density1.11.42.7-1.41.4-1.31.31.31.3-1.4-1.1-1.11.61.2-1.01.1-1.60.80.80.7-0.6
Condit. Reinf. active minus inactive responses0.60.71.60.5-0.70.7-0.7-0.6-0.80.70.90.9-0.9-0.80.9-0.9-0.0-1.0-1.0-1.31.2
Condit. Reinf. active-inactive response ratio1.61.73.21.0-1.11.3-1.3-0.9-1.31.31.41.3-1.1-1.31.4-1.40.1-1.6-1.0-1.81.7
Condit. Reinf. active responses0.10.21.00.0-0.20.2-0.2-0.3-0.20.10.40.3-0.6-0.30.4-0.3-0.2-0.4-1.0-0.50.4
Condit. Reinf. inactive responses0.20.20.6-0.50.4-0.50.50.10.5-0.6-0.4-0.40.00.5-0.50.5-0.00.6-0.30.8-0.7
Incentive salience index mean0.60.81.90.5-0.70.8-0.8-0.8-0.80.71.00.9-1.2-0.91.0-0.90.2-0.9-1.4-1.11.0
Condit. Reinf. lever presses0.40.51.70.4-0.60.7-0.7-0.8-0.70.40.80.7-1.0-0.70.8-0.60.4-0.6-1.3-0.40.4
Condit. Reinf. active minus inactive responses7.39.514.73.6-3.23.0-3.0-3.5-3.33.02.93.0-3.8-3.32.9-3.22.6-2.9-3.5-2.02.3
Condit. Reinf. active-inactive response ratio1.11.23.31.2-1.10.8-0.8-1.5-1.10.80.81.1-1.7-1.11.0-1.01.2-0.8-1.8-0.60.5
Condit. Reinf. active responses10.815.020.04.4-4.03.9-3.9-4.3-4.13.83.73.7-4.5-4.23.6-4.12.9-3.8-4.3-2.93.2
Condit. Reinf. inactive responses6.68.610.63.3-3.03.1-3.1-3.0-3.12.92.92.7-3.1-3.22.6-3.21.7-3.1-3.2-2.42.9
Condit. Reinf. lever presses18.625.837.86.1-5.65.4-5.4-5.5-5.55.55.25.1-5.6-5.35.1-5.24.7-4.6-4.4-3.13.3
Condit. Reinf. lever reinforcers received11.916.521.94.6-4.34.1-4.1-4.5-4.34.03.93.9-4.7-4.43.8-4.33.2-3.9-4.5-2.93.2
Conditioned reinforcement - actives0.50.92.21.3-1.11.1-1.1-0.8-0.91.10.90.9-1.1-0.70.9-0.71.5-0.4-0.0-0.30.2
Conditioned reinforcement - inactives0.50.81.3-0.30.9-0.90.91.01.0-0.9-1.0-1.00.40.9-1.01.0-0.50.90.10.9-1.1
Conditioned locomotion0.40.63.81.2-0.80.5-0.5-0.5-0.50.50.40.5-0.8-0.10.5-0.12.00.50.90.7-0.9
Patch foraging indifference point 0 sec4.68.511.03.3-3.33.2-3.2-3.0-3.23.33.23.2-2.9-3.03.2-3.02.8-2.6-1.4-2.11.8
Patch foraging indifference point AUC0.50.71.80.6-0.60.7-0.7-0.7-0.80.80.70.7-0.8-0.90.7-0.9-0.2-1.1-1.3-0.91.1
Delay disc. indifference point, 0s delay1.11.22.21.3-1.10.9-0.9-1.4-1.10.91.11.3-1.4-1.11.3-1.01.0-0.9-1.5-0.30.7
Delay disc. indifference point, 16s delay0.10.10.4-0.00.4-0.30.30.40.4-0.3-0.4-0.50.20.4-0.40.4-0.20.40.20.6-0.5
Delay disc. indifference point, 2s delay1.01.22.31.5-1.01.0-1.0-1.4-1.01.01.01.3-1.5-1.21.2-1.01.0-1.0-1.1-0.20.5
Delay disc. indifference point, 24s delay0.80.91.7-1.11.1-0.90.91.11.0-0.9-1.2-1.30.81.0-1.20.9-1.30.70.30.4-0.3
Delay disc. indifference point, 4s delay1.31.36.91.1-0.80.5-0.5-1.5-0.90.50.91.4-1.9-1.11.2-0.90.6-0.9-2.6-0.30.7
Delay disc. indifference point, 8s delay0.30.30.70.8-0.50.6-0.6-0.4-0.50.60.60.6-0.8-0.50.5-0.50.4-0.5-0.4-0.20.3
Indifference point function ln k0.40.73.61.1-1.00.8-0.8-0.8-0.70.60.90.8-0.7-0.40.9-0.41.90.20.70.4-0.5
Indifference point function log k0.40.73.61.1-1.00.8-0.8-0.8-0.70.60.90.8-0.7-0.40.9-0.41.90.20.70.4-0.5
Patch foraging total patch changes 0 sec3.97.39.73.1-3.03.0-3.0-2.8-2.93.02.92.9-2.7-2.82.9-2.82.6-2.4-1.4-1.91.7
Patch foraging total patch changes 12 sec3.03.95.11.7-1.92.1-2.1-1.9-2.12.32.02.0-1.8-2.12.0-2.20.9-2.2-1.5-2.22.1
Patch foraging total patch changes 18 sec3.45.26.71.9-2.32.5-2.5-2.3-2.42.62.52.5-1.9-2.42.5-2.51.3-2.4-1.7-2.42.2
Patch foraging total patch changes 24 sec0.50.91.70.8-0.91.0-1.0-1.2-1.00.90.81.0-1.0-1.10.8-1.10.5-1.1-1.3-0.80.9
Patch foraging total patch changes 6 sec1.42.23.92.0-1.61.6-1.6-1.3-1.61.81.51.5-1.7-1.41.5-1.51.5-1.3-0.7-1.10.7
Patch foraging time to switch 0 sec3.57.18.4-2.92.9-2.72.72.92.9-2.7-2.8-2.82.82.8-2.82.8-2.22.61.82.1-2.2
Patch foraging water rate 0 sec2.45.06.72.5-2.62.4-2.4-2.6-2.52.42.42.4-2.1-2.42.4-2.32.3-1.9-1.1-1.51.5
Patch foraging water rate 12 sec1.02.03.91.6-1.71.6-1.6-1.6-1.51.51.41.6-1.6-1.31.4-1.32.0-0.8-0.9-0.80.3
Patch foraging water rate 18 sec0.61.01.30.9-1.11.0-1.0-1.1-1.11.01.01.1-1.0-1.01.0-1.00.9-0.8-1.1-0.80.7
Patch foraging water rate 24 sec0.40.63.31.0-1.00.7-0.7-0.8-0.70.80.70.7-0.7-0.40.7-0.31.80.20.30.2-0.4
Patch foraging water rate 6 sec0.30.51.50.9-0.90.8-0.8-0.8-0.70.70.80.7-0.4-0.50.7-0.51.2-0.2-0.1-0.2-0.1
Seeking ratio, delayed vs. immediate footshock2.42.93.9-2.01.7-1.91.91.71.8-1.9-1.9-1.81.91.8-1.81.8-1.31.71.11.2-1.3
Distance traveled before self-admin0.20.30.7-0.60.7-0.50.50.80.6-0.6-0.6-0.40.10.6-0.50.5-0.90.30.00.3-0.3
Distance traveled after self-admin2.22.74.3-1.21.5-1.81.81.61.7-1.9-1.7-1.71.01.9-1.71.9-0.52.11.12.0-1.9
Extensor digitorum longus weight0.20.83.8-0.2-0.20.5-0.5-0.0-0.50.70.50.4-0.6-0.70.5-0.9-1.2-1.3-1.1-1.91.5
Bone: elastic displacement2.22.53.6-1.51.6-1.61.61.91.6-1.5-1.6-1.71.81.7-1.81.6-1.11.51.61.0-1.5
Bone: elastic work2.22.84.1-1.61.7-1.71.72.01.7-1.5-1.7-1.81.91.8-1.91.8-1.11.71.51.3-1.8
Bone: endosteal estimation2.24.97.11.8-2.02.3-2.3-2.1-2.32.42.12.2-1.9-2.42.2-2.50.6-2.6-1.9-2.72.7
Bone: endosteal perimeter3.06.47.92.3-2.52.7-2.7-2.5-2.62.72.52.5-2.4-2.72.6-2.81.1-2.8-1.9-2.72.8
Epididymis fat weight0.20.71.9-1.41.0-1.01.00.70.9-1.0-1.1-0.90.50.6-1.10.7-1.20.3-0.2-0.2-0.2
Delta time in closed arm before/after self-admin0.40.32.8-0.60.7-0.30.30.60.4-0.4-0.4-0.3-0.00.2-0.30.1-1.7-0.4-0.6-0.60.6
Delta time in open arm before/after self-admin2.82.73.51.7-1.91.8-1.8-1.8-1.91.81.81.6-1.0-1.81.6-1.91.2-1.7-0.6-1.81.7
Diff in mean of infusions in LGA sessions5.87.08.9-2.93.0-2.92.92.82.9-2.8-2.9-2.82.42.8-2.82.8-2.42.51.52.2-2.0
Delay discount exponential model param0.10.10.6-0.40.0-0.00.00.30.0-0.0-0.1-0.30.60.2-0.20.1-0.10.10.8-0.30.1
Extinction: sum of active levers before priming0.00.00.4-0.10.00.1-0.1-0.0-0.10.0-0.1-0.1-0.3-0.2-0.1-0.1-0.2-0.2-0.7-0.10.3
Active lever presses in extinction session 60.70.74.81.2-0.80.4-0.4-0.5-0.40.40.40.4-0.6-0.10.40.12.20.71.01.3-1.2
Bone: final force0.10.10.90.10.0-0.10.10.40.00.3-0.1-0.10.70.1-0.0-0.0-0.2-0.11.0-0.30.2
Bone: final moment0.10.10.40.4-0.20.2-0.20.2-0.30.50.20.20.4-0.20.3-0.3-0.1-0.40.6-0.50.4
Food consumed during 24 hour testing period2.33.25.12.3-2.01.8-1.8-2.1-1.81.61.92.1-2.0-1.62.0-1.62.0-1.1-2.0-0.11.2
Glucose0.00.00.1-0.20.2-0.30.30.30.2-0.3-0.2-0.10.20.1-0.20.1-0.20.10.1-0.2-0.1
Heart weight0.60.91.71.3-1.21.0-1.0-0.9-1.11.10.90.9-1.0-0.90.8-1.01.1-0.8-0.2-0.90.6
Delay discount hyperbolic model param0.20.21.0-0.50.2-0.20.20.50.2-0.2-0.3-0.50.80.4-0.40.3-0.10.41.0-0.1-0.1
Intermittent access intake day 1-15 change0.40.82.31.5-1.11.1-1.1-0.8-0.91.11.00.9-0.5-0.70.9-0.71.5-0.30.50.2-0.1
Intermittent access intake escalation0.51.02.71.6-1.21.2-1.2-0.9-1.01.21.11.1-0.7-0.81.1-0.81.6-0.40.40.1-0.1
Intermittent access intake escalation 20.80.91.81.3-1.21.1-1.1-1.0-1.01.11.11.1-0.5-0.91.0-0.91.3-0.60.2-0.30.1
Intermitt. access day 1 inactive lever presses0.82.94.1-1.71.9-2.02.01.71.8-2.0-2.0-1.91.61.7-1.91.7-1.61.50.41.4-1.3
Intermitt. access day 15 inactive lever presses1.32.73.5-1.61.7-1.81.81.61.7-1.8-1.9-1.81.21.8-1.81.8-1.01.80.41.6-1.7
Intermitt. access escalation Index0.00.00.10.0-0.00.0-0.00.10.00.0-0.1-0.2-0.20.0-0.20.0-0.1-0.0-0.30.10.0
Intermittent access day 1 total infusions0.40.71.51.2-0.90.8-0.8-0.7-0.80.80.90.8-1.2-0.70.8-0.70.9-0.6-1.0-0.60.3
Intermittent access day 15 total infusions0.81.23.41.8-1.31.2-1.2-0.9-1.11.21.21.1-1.0-0.91.1-0.91.6-0.5-0.1-0.10.0
Intermittent access terminal intake (last 3 days)1.41.83.81.9-1.61.6-1.6-1.3-1.51.61.61.5-1.2-1.21.5-1.31.7-0.9-0.3-0.70.5
Intermittent access total infusions1.11.32.11.4-1.31.3-1.3-1.0-1.21.31.31.2-0.9-1.11.2-1.21.1-1.0-0.4-1.00.7
Intermittent access day 1 locomotion0.10.10.30.5-0.30.2-0.20.1-0.20.20.30.2-0.1-0.00.2-0.00.50.10.3-0.1-0.3
Intermittent access day 15 total locomotion0.40.72.61.3-1.01.0-1.0-0.6-0.81.00.90.8-0.6-0.50.8-0.51.6-0.10.60.1-0.4
Intermittent access total locomotion0.40.51.01.0-0.80.9-0.9-0.5-0.70.90.80.7-0.5-0.50.7-0.61.0-0.40.1-0.50.1
Intermittent access standard deviation0.30.71.80.6-0.70.8-0.8-0.8-0.80.80.80.8-0.6-0.90.8-0.90.0-1.0-1.0-1.41.0
Left kidney weight0.52.16.00.6-0.91.1-1.1-1.3-1.21.11.11.4-1.6-1.51.2-1.5-0.4-1.9-2.5-2.12.1
Right kidney weight0.62.66.30.7-1.11.3-1.3-1.5-1.51.41.21.5-1.2-1.81.3-1.8-0.4-2.2-2.2-2.32.5
Cocaine induced anxiety0.91.32.8-1.71.2-1.01.01.41.1-1.0-1.1-1.11.51.1-1.11.1-1.30.81.30.3-0.5
Post-drug Anxiety1.21.32.4-1.51.3-1.11.11.41.2-1.1-1.1-1.21.21.2-1.21.1-1.50.81.00.5-0.5
Baseline Anxiety0.20.30.70.7-0.40.5-0.5-0.5-0.50.50.60.5-0.8-0.50.5-0.50.2-0.5-0.8-0.30.5
Tail length1.35.013.00.8-1.51.9-1.9-1.8-2.01.81.81.8-2.2-2.31.7-2.4-0.7-3.0-3.3-3.63.4
Length with tail0.73.07.40.7-1.21.4-1.4-1.4-1.61.41.31.4-1.7-1.91.3-1.9-0.5-2.3-2.6-2.72.6
Length without tail0.10.40.7-0.40.7-0.80.80.40.6-0.8-0.8-0.70.60.5-0.80.6-0.60.4-0.30.6-0.3
Times rat made contact with spout0.20.21.1-0.60.2-0.10.10.10.0-0.2-0.00.10.6-0.1-0.1-0.2-1.1-0.5-0.5-0.60.9
Lifetime Intake1.21.42.41.5-1.41.4-1.4-1.1-1.31.41.41.3-0.9-1.11.3-1.21.3-0.9-0.4-0.90.6
Liver weight, left0.20.31.1-0.40.1-0.00.0-0.2-0.1-0.1-0.1-0.10.3-0.4-0.2-0.4-1.0-0.7-0.7-0.91.0
Liver weight, right0.61.15.3-1.61.1-1.01.00.60.7-0.9-0.9-0.91.20.3-0.90.2-2.3-0.4-1.1-0.81.1
Locomotor activity0.91.42.01.2-1.41.2-1.2-1.2-1.31.11.41.4-1.1-1.21.3-1.21.1-1.0-0.8-1.01.0
Locomotor testing distance2.13.84.61.6-2.11.9-1.9-2.1-2.11.82.22.1-1.9-2.12.0-2.11.4-1.9-1.7-2.11.9
Locomotor testing rearing0.91.84.20.4-1.31.4-1.4-1.4-1.51.31.41.3-0.6-1.61.2-1.60.4-1.7-1.0-2.01.6
Locomotion in novel chamber0.40.41.91.1-0.80.5-0.5-0.5-0.60.50.80.7-1.0-0.30.7-0.31.40.10.00.2-0.3
Locomotion in novel chamber post-restriction1.11.85.41.8-1.61.5-1.5-1.4-1.31.51.41.4-0.9-1.11.4-1.02.3-0.50.7-0.0-0.2
Fecal boli incidents, locomotor time 10.20.21.40.8-0.70.3-0.3-0.4-0.50.30.40.4-0.5-0.30.3-0.31.20.10.20.20.1
Change in fecal boli incidents, locomotor task0.80.81.5-1.01.1-0.90.90.91.0-0.8-1.1-1.00.70.9-1.20.9-0.90.80.60.7-0.7
Time >=10cm from walls, locomotor time 10.91.03.21.5-1.21.0-1.0-1.1-1.01.01.00.8-1.4-0.81.0-0.71.8-0.3-0.20.1-0.1
Bouts of movement, locomotor time 10.20.31.90.6-0.1-0.10.1-0.4-0.1-0.0-0.10.0-1.4-0.10.0-0.10.30.0-1.40.3-0.0
Total resting periods, locomotor time 10.20.20.80.40.2-0.40.40.10.3-0.3-0.6-0.4-0.90.3-0.30.40.30.5-0.70.8-0.5
Rest time, locomotor task time 10.70.81.7-0.20.8-1.11.10.50.9-1.1-1.2-0.9-0.80.9-0.91.0-0.11.1-0.41.3-0.8
Distance moved, locomotor task time 10.91.33.40.2-0.91.3-1.3-0.6-1.01.31.51.30.8-1.11.3-1.2-0.1-1.50.2-1.81.3
Vertical activity count, locomotor time 10.81.83.40.8-1.21.7-1.7-1.0-1.31.71.71.50.2-1.41.6-1.50.4-1.60.3-1.81.3
Time >=10cm from walls, locomotor time 20.71.12.91.3-1.10.8-0.8-1.4-1.10.80.70.9-1.7-1.10.9-1.01.1-0.8-1.2-0.30.9
Bouts of movement, locomotor time 20.50.81.60.9-0.80.8-0.8-1.0-0.80.90.71.1-1.2-1.00.7-0.90.6-0.9-1.3-0.40.4
Total resting periods, locomotor time 20.20.31.00.6-0.40.5-0.5-0.7-0.50.50.40.9-0.9-0.60.4-0.60.4-0.6-1.0-0.10.1
Rest time, locomotor task time 21.92.43.3-1.71.8-1.71.71.71.8-1.7-1.7-1.51.51.7-1.61.6-1.71.41.11.1-0.9
Distance moved, locomotor task time 22.63.14.01.7-2.01.8-1.8-2.0-2.01.92.01.8-1.3-2.01.9-1.91.6-1.7-1.1-1.51.4
Vertical activity count, locomotor time 21.82.53.71.2-1.61.8-1.8-1.6-1.71.91.81.6-1.1-1.71.8-1.81.0-1.7-0.7-1.71.4
Light reinforcement 10.81.93.4-1.51.6-1.51.51.51.5-1.5-1.5-1.51.31.3-1.51.3-1.80.90.30.7-0.5
Light reinforcement 20.10.20.70.20.4-0.50.50.40.4-0.6-0.5-0.5-0.30.5-0.60.5-0.10.6-0.20.8-0.5
Bone: marrow area2.04.36.71.6-1.92.2-2.2-1.9-2.12.22.02.0-1.8-2.32.0-2.30.5-2.5-1.7-2.62.6
Bone: maximum diameter2.85.26.82.2-2.32.5-2.5-2.0-2.42.62.22.2-2.1-2.42.3-2.51.2-2.5-1.3-2.62.5
Bone: maximum force0.10.20.70.5-0.30.4-0.40.2-0.30.70.20.20.3-0.30.3-0.30.0-0.40.8-0.40.4
Bone: maximum moment0.20.30.80.7-0.60.6-0.6-0.1-0.60.90.50.50.0-0.50.6-0.60.1-0.60.5-0.70.7
Mean time between licks in bursts3.07.410.02.6-2.62.5-2.5-3.1-2.82.52.62.8-2.8-3.12.7-3.01.2-3.1-3.2-2.13.1
Mean num. licks in bursts2.94.56.02.4-2.52.3-2.3-2.3-2.32.22.32.3-2.4-2.12.4-2.12.4-1.6-1.3-1.51.3
Cd content in liver0.10.10.7-0.80.4-0.30.30.20.2-0.2-0.4-0.20.20.1-0.20.1-0.8-0.2-0.1-0.60.3
Co content in liver1.61.92.80.8-1.31.5-1.5-1.6-1.41.31.51.5-1.0-1.51.7-1.50.7-1.5-1.4-1.61.3
Cu content in liver0.80.94.80.2-0.50.5-0.5-1.2-0.70.20.50.6-1.2-1.00.7-0.9-0.2-1.1-2.2-1.21.3
Fe content in liver0.10.10.2-0.20.3-0.50.50.20.3-0.4-0.4-0.30.30.2-0.40.3-0.20.20.30.1-0.2
K content in liver0.00.00.3-0.10.2-0.00.0-0.20.1-0.20.1-0.0-0.2-0.10.0-0.0-0.4-0.1-0.5-0.00.3
Mg content in liver0.10.10.20.2-0.20.2-0.2-0.5-0.20.10.20.3-0.1-0.20.3-0.20.5-0.10.10.20.0
Mn content in liver2.12.33.6-1.11.3-1.51.51.41.5-1.5-1.5-1.41.71.6-1.41.7-0.31.81.81.9-1.7
Na content in liver0.30.41.10.8-0.70.5-0.5-0.8-0.60.40.70.7-0.3-0.60.8-0.51.0-0.20.40.30.1
Rb content in liver0.70.81.40.5-1.01.0-1.0-0.8-1.00.91.20.9-0.5-0.90.9-0.90.5-0.9-0.4-1.20.8
Se content in liver7.18.411.8-2.83.1-3.43.42.83.2-3.1-3.3-3.02.43.1-3.03.1-2.12.91.72.7-2.3
Sr content in liver0.10.10.7-0.0-0.20.1-0.1-0.1-0.10.20.10.30.50.00.30.00.60.20.80.1-0.4
Zn content in liver3.33.75.81.7-1.91.9-1.9-2.4-2.01.81.92.0-2.2-2.11.9-2.01.4-1.9-2.2-1.61.8
Bone: minimum diameter1.32.46.40.7-1.11.4-1.4-1.1-1.41.41.21.4-1.1-1.71.4-1.7-0.6-2.1-1.7-2.52.4
Time in familiar zone, hab. session 10.10.10.3-0.30.20.1-0.10.10.0-0.10.10.20.3-0.00.3-0.1-0.5-0.2-0.20.10.4
Time in novel zone, hab. session 10.10.10.3-0.20.2-0.30.30.30.2-0.1-0.3-0.40.10.2-0.50.2-0.30.10.2-0.4-0.2
Total zone transitions, hab. session 10.10.10.50.4-0.10.2-0.20.10.00.10.10.2-0.00.20.20.20.70.40.60.7-0.7
Total locomotion distance, hab. session 10.30.42.0-1.10.7-0.50.50.30.4-0.6-0.6-0.60.70.1-0.60.1-1.4-0.3-0.2-0.50.7
Locomotion velocity, hab. session 10.10.21.0-0.80.4-0.30.30.10.2-0.4-0.4-0.40.50.0-0.40.0-1.0-0.3-0.1-0.50.6
Time in familiar zone, hab. session 22.32.53.81.4-1.61.8-1.8-1.2-1.71.61.91.8-1.3-1.61.8-1.70.8-1.7-1.3-1.51.6
Time in novel zone, hab. session 21.21.32.2-0.91.0-1.41.40.61.1-1.2-1.5-1.40.91.1-1.31.2-0.21.30.71.1-1.3
Total zone transitions, hab. session 20.81.03.41.5-1.10.9-0.9-1.2-0.91.00.81.0-1.3-0.70.9-0.61.8-0.1-0.50.7-0.3
Total locomotion distance, hab. session 20.30.42.00.1-0.20.1-0.1-0.7-0.40.20.10.2-0.8-0.60.2-0.6-0.6-0.9-1.4-0.61.2
Locomotion velocity, hab. session 20.30.41.9-0.1-0.0-0.00.0-0.6-0.30.0-0.10.1-0.6-0.60.0-0.5-0.8-0.8-1.4-0.71.2
Novel to familiar place preference ratio0.00.00.10.20.0-0.10.1-0.20.1-0.0-0.3-0.4-0.30.0-0.40.10.30.20.10.3-0.2
Novelty place preference0.10.10.3-0.00.1-0.20.2-0.20.1-0.1-0.4-0.5-0.20.1-0.50.20.20.30.00.4-0.2
Time in novel zone, NPP test0.00.10.20.2-0.1-0.00.0-0.4-0.10.1-0.2-0.2-0.4-0.1-0.30.00.50.1-0.20.3-0.2
Total zone transitions, NPP test0.10.21.20.5-0.1-0.20.2-0.20.1-0.2-0.3-0.1-0.30.2-0.00.20.70.5-0.31.1-0.5
Total locomotion distance, NPP test0.50.71.5-0.90.9-1.21.20.20.7-1.1-1.2-0.90.10.4-1.00.5-1.20.2-1.20.40.3
Locomotion velocity, NPP test0.91.32.7-1.31.3-1.61.60.51.1-1.5-1.6-1.30.50.7-1.40.8-1.50.5-0.90.60.1
Intraocular pressure0.20.31.40.6-0.50.3-0.3-0.1-0.20.40.30.40.1-0.00.2-0.01.20.30.90.4-0.9
Delta distance traveled before/after self-admin0.20.21.40.6-0.30.0-0.0-0.2-0.1-0.00.1-0.0-0.40.20.10.21.20.60.40.9-0.7
Delta ambulatory time before/after self-admin0.20.31.50.6-0.2-0.00.0-0.20.0-0.1-0.0-0.1-0.50.30.00.31.20.80.31.0-0.9
Parametrial fat weight0.20.51.7-0.60.9-0.80.81.00.7-0.6-0.9-0.80.40.6-0.90.5-1.30.20.20.1-0.0
Pavlov. Cond. lever latency1.92.43.7-1.31.6-1.71.71.61.6-1.4-1.9-1.91.41.6-1.81.6-1.11.51.71.0-1.3
Pavlov. Cond. magazine entry latency4.05.16.52.2-2.52.4-2.4-2.5-2.52.42.52.5-2.0-2.42.5-2.41.8-2.2-1.5-1.81.9
Pavlov. Cond. change in total contacts1.21.22.01.1-1.20.9-0.9-1.4-1.20.91.21.3-1.3-1.21.2-1.11.0-1.0-1.3-0.41.0
Pavlov. Cond. index score3.74.76.31.8-2.32.3-2.3-2.3-2.32.12.52.5-2.0-2.32.4-2.31.5-2.1-1.9-1.71.9
Pavlov. Cond. latency score3.54.56.11.8-2.32.3-2.3-2.3-2.32.12.52.4-1.9-2.22.4-2.21.6-2.1-1.7-1.61.9
Pavlov. Cond. lever contacts1.92.33.31.1-1.51.6-1.6-1.6-1.61.31.81.8-1.5-1.61.7-1.60.9-1.5-1.8-1.11.3
Pavlov. Cond. magazine entry number4.15.26.7-2.12.5-2.42.42.52.5-2.3-2.5-2.62.22.4-2.52.4-1.82.21.81.8-1.8
Pavlov. Cond. intertrial magazine entries2.12.63.7-1.71.8-1.81.81.51.8-1.9-1.9-1.81.21.7-1.91.7-1.21.60.41.2-1.2
Pavlov. Cond. lever-magazine prob. diff.3.03.85.11.6-2.02.1-2.1-2.0-2.11.92.32.2-1.7-2.12.2-2.11.3-1.9-1.7-1.61.8
Pavlov. Cond. response bias2.02.53.41.3-1.61.6-1.6-1.7-1.71.51.81.8-1.6-1.61.8-1.61.0-1.5-1.8-1.21.4
Pavlov. Cond. lever latency19.526.540.2-6.35.7-5.55.55.75.5-5.5-5.3-5.15.85.3-5.25.2-5.24.44.42.7-2.9
Pavlov. Cond. magazine entry latency4.35.28.12.8-2.72.7-2.7-2.5-2.52.82.52.3-1.9-2.22.5-2.22.8-1.7-0.3-1.00.9
Pavlov. Cond. change in total contacts10.817.325.75.1-4.74.3-4.3-4.9-4.54.44.14.2-4.8-4.34.1-4.14.5-3.4-3.5-2.12.1
Pavlov. Cond. index score14.219.127.45.2-4.94.8-4.8-4.9-4.74.84.54.5-4.7-4.54.5-4.44.6-3.7-2.9-2.32.3
Pavlov. Cond. latency score12.416.424.24.9-4.64.5-4.5-4.6-4.44.54.24.1-4.3-4.14.2-4.04.4-3.3-2.6-2.02.0
Pavlov. Cond. lever contacts18.525.538.26.2-5.65.4-5.4-5.6-5.45.45.24.9-5.8-5.25.1-5.15.0-4.3-4.3-2.82.9
Pavlov. Cond. magazine entry number6.47.912.9-3.33.3-3.13.13.33.1-3.2-2.9-2.93.02.8-2.92.7-3.62.01.31.3-1.0
Pavlov. Cond. intertrial magazine entries0.40.62.70.2-0.20.3-0.3-0.4-0.50.10.40.4-0.6-0.70.3-0.8-0.9-1.1-1.6-1.31.6
Pavlov. Cond. lever-magazine prob. diff.13.417.825.45.0-4.84.6-4.6-4.8-4.64.74.44.3-4.5-4.44.4-4.34.4-3.6-2.9-2.32.3
Pavlov. Cond. response bias19.126.037.56.1-5.75.5-5.5-5.6-5.55.55.35.1-5.7-5.25.2-5.15.2-4.3-3.9-2.92.8
Time in closed arm before self-admin0.30.42.70.9-0.90.5-0.5-0.7-0.60.50.60.6-0.7-0.30.5-0.31.60.20.10.4-0.4
Time in closed arm after self-admin1.21.31.9-0.91.1-1.21.21.21.2-1.2-1.1-1.10.61.4-1.11.3-0.61.40.41.3-1.3
Time in open arm before self-admin1.71.93.2-1.41.8-1.51.51.51.6-1.6-1.5-1.40.81.4-1.41.5-1.61.10.31.1-1.0
Time in open arm after self-admin1.01.12.70.7-0.91.2-1.2-0.9-1.11.11.11.0-0.5-1.21.0-1.30.1-1.5-0.4-1.71.3
Bone: periosteal estimation1.83.87.21.5-1.82.0-2.0-1.7-2.02.21.81.8-1.4-2.11.9-2.20.5-2.4-1.3-2.72.4
Bone: periosteal perimeter2.54.36.51.9-2.02.2-2.2-1.9-2.22.12.12.0-2.0-2.22.1-2.30.7-2.4-1.7-2.52.5
Bone: post-yield work0.50.71.30.8-0.71.1-1.1-0.2-0.81.10.91.0-0.4-0.71.1-0.90.1-1.00.4-0.91.0
Progressive ratio test 1 active lever presses0.30.40.9-0.20.6-0.50.50.80.7-0.5-0.5-0.60.60.8-0.60.8-0.00.81.00.7-0.9
Progressive ratio test 1 breakpoint0.30.40.9-0.20.6-0.50.50.80.7-0.5-0.5-0.60.60.8-0.60.7-0.10.80.90.7-1.0
Progressive ratio test 1 inactive lever presses0.40.51.0-0.40.7-0.60.61.00.7-0.6-0.7-0.80.80.8-0.80.8-0.40.80.50.6-1.0
Progressive ratio test 2 active lever presses0.40.50.80.9-0.70.9-0.9-0.5-0.70.90.80.8-0.7-0.60.7-0.70.6-0.6-0.1-0.70.4
Progressive ratio test 2 breakpoint0.40.50.80.9-0.70.9-0.9-0.5-0.70.90.80.8-0.7-0.60.7-0.70.6-0.6-0.1-0.70.3
Progressive ratio test 2 inactive lever presses0.10.10.30.5-0.40.5-0.5-0.1-0.30.50.30.2-0.6-0.20.2-0.30.5-0.2-0.2-0.5-0.2
Incentive Sensitization - Responses1.31.92.61.4-1.41.6-1.6-1.3-1.41.61.51.4-1.6-1.41.4-1.41.0-1.3-0.9-1.31.0
Incentive Sensitization - Breakpoint1.31.72.31.4-1.31.5-1.5-1.2-1.31.51.41.3-1.5-1.31.3-1.31.0-1.2-0.7-1.20.9
Sum of active levers in priming session hrs 5-60.10.10.3-0.0-0.1-0.20.2-0.2-0.00.0-0.3-0.2-0.4-0.0-0.10.00.30.1-0.60.4-0.2
Progressive ratio0.10.20.90.4-0.60.3-0.3-0.4-0.40.40.40.20.3-0.30.3-0.30.9-0.00.40.2-0.1
Food seeking constrained by brief footshock2.12.63.31.7-1.61.6-1.6-1.8-1.71.61.51.7-1.5-1.81.4-1.81.0-1.8-1.3-1.41.7
Seeking ratio, punishment vs. effort0.91.33.10.9-0.81.1-1.1-1.1-1.11.01.01.2-1.2-1.30.9-1.3-0.1-1.5-1.2-1.51.7
Retroperitoneal fat weight0.72.916.0-2.61.9-1.41.41.51.2-1.2-1.5-1.51.30.5-1.60.4-4.0-0.8-0.6-2.31.6
Reaction time number correct0.10.31.50.5-0.0-0.20.20.10.2-0.3-0.2-0.2-0.30.4-0.30.50.90.80.41.2-0.9
Reaction time mean minus median0.71.72.21.3-1.41.4-1.4-1.3-1.41.41.41.4-0.9-1.41.4-1.50.7-1.5-0.8-1.31.4
Reaction time mean minus median AUC0.61.52.01.4-1.41.3-1.3-1.3-1.41.31.31.2-0.9-1.31.2-1.31.1-1.2-0.6-0.91.1
Reaction time num false alarms1.11.53.4-1.71.5-1.21.21.31.3-1.2-1.3-1.61.41.1-1.41.0-1.90.60.30.3-0.1
Reaction time num false alarms AUC0.71.01.8-1.31.2-1.01.01.01.1-1.0-1.1-1.31.10.9-1.20.9-1.30.70.20.5-0.2
Reaction time trials correct on left0.10.31.50.5-0.0-0.20.20.10.2-0.3-0.2-0.2-0.30.4-0.30.50.90.80.41.2-0.9
Reaction time trials on left0.20.31.60.5-0.0-0.20.20.10.2-0.3-0.2-0.2-0.30.4-0.30.50.90.80.41.3-0.9
Reaction time mean0.40.61.9-0.80.8-0.70.70.80.6-0.5-0.8-0.71.30.4-0.70.4-1.4-0.01.0-0.30.2
Reaction time mean AUC0.71.22.6-1.21.2-1.11.11.21.0-1.0-1.3-1.21.60.9-1.20.8-1.60.51.10.2-0.2
Median of all reaction times1.11.53.2-1.41.3-1.31.31.31.2-1.0-1.4-1.31.81.0-1.30.9-1.70.51.40.2-0.2
Reaction time omissions0.00.10.20.2-0.00.1-0.1-0.1-0.10.1-0.1-0.10.0-0.3-0.1-0.3-0.4-0.5-0.4-0.30.5
Reaction time false alarm rate0.91.23.1-1.61.3-1.11.11.11.1-0.9-1.2-1.31.50.8-1.20.8-1.80.40.30.00.0
Reaction time premature initiation rate3.24.58.51.5-1.92.2-2.2-1.9-2.22.32.12.2-1.3-2.42.0-2.50.4-2.7-1.2-2.92.7
Reaction time premature initiations1.83.24.21.7-1.92.0-2.0-1.7-2.02.11.91.9-1.3-2.01.8-2.00.9-2.0-0.7-2.02.0
Std. dev. reaction times0.50.92.30.5-0.80.9-0.9-0.8-1.01.00.80.8-0.2-1.10.8-1.2-0.2-1.4-0.4-1.51.5
Reaction time trials completed0.20.31.60.5-0.0-0.20.20.10.2-0.3-0.2-0.2-0.30.4-0.30.50.90.80.41.3-0.9
Reaction time trials AUC0.10.21.10.6-0.1-0.10.1-0.10.1-0.2-0.1-0.2-0.40.3-0.20.30.80.70.21.0-0.7
Run reversals in cocaine runway, females0.90.93.8-0.5-0.00.5-0.5-0.1-0.40.50.50.50.1-0.80.5-0.9-1.6-1.5-0.8-1.91.9
Run reversals in cocaine runway, males0.10.10.6-0.10.3-0.20.20.40.3-0.2-0.00.10.60.3-0.00.2-0.30.20.80.2-0.1
Latency to leave start box in cocaine runway2.22.54.0-1.92.0-1.81.81.51.7-1.7-1.7-1.71.91.4-1.61.5-2.01.00.91.1-0.8
Latency to leave start box in cocaine runway, F1.51.84.8-1.71.8-1.61.61.21.4-1.5-1.4-1.31.51.0-1.31.0-2.20.50.30.7-0.1
Latency to leave start box in cocaine runway, M0.70.71.0-0.70.8-0.70.70.80.8-0.7-0.8-0.80.90.9-0.80.9-0.30.90.90.9-1.0
Std. dev. time between licks in bursts2.02.75.11.2-1.31.5-1.5-1.8-1.61.41.71.6-1.3-1.91.6-1.90.2-2.1-2.1-1.42.3
Total sessions with >9 infusions1.61.92.81.5-1.61.6-1.6-1.5-1.51.61.71.6-0.6-1.41.6-1.41.5-1.2-0.1-0.80.8
Short access day 1 total inactive lever presses0.00.00.10.00.2-0.20.20.20.2-0.2-0.2-0.30.30.2-0.20.2-0.20.2-0.10.1-0.3
Short access day 10 total inactive lever presses0.61.52.0-1.31.3-1.41.41.21.3-1.4-1.4-1.30.81.3-1.31.3-1.01.20.20.8-1.2
Short access day 1 total infusions2.73.64.42.0-2.02.1-2.1-2.0-2.12.12.12.0-1.5-2.12.0-2.01.6-1.9-1.3-1.61.5
Short access day 10 total infusions0.91.11.51.2-1.21.2-1.2-1.2-1.21.21.11.0-0.9-1.11.0-1.11.1-1.0-0.7-0.80.8
Short access total infusions1.41.82.91.7-1.51.5-1.5-1.4-1.41.51.51.4-1.2-1.41.4-1.31.4-1.1-0.7-0.80.8
Short access day 1 locomotion1.51.94.31.9-1.71.6-1.6-1.3-1.51.61.51.6-0.8-1.31.6-1.22.1-0.80.4-0.40.2
Short access day 10 total locomotion0.91.62.31.3-1.51.4-1.4-1.4-1.41.41.41.5-0.8-1.31.5-1.31.5-1.0-0.2-0.90.6
Short access total locomotion0.50.51.40.9-0.90.8-0.8-0.6-0.70.80.80.90.1-0.60.9-0.61.2-0.31.0-0.20.1
One hour access (0.3 mA shock)0.91.01.81.1-1.31.2-1.2-1.0-1.11.21.11.1-0.6-1.01.1-1.01.3-0.70.2-0.90.5
Compulsive drug intake0.91.12.6-0.50.8-1.01.00.81.0-1.0-1.1-1.00.61.1-1.01.20.31.41.31.6-1.3
One hour access (shock baseline)1.01.52.21.3-1.51.4-1.4-1.3-1.41.41.41.4-0.8-1.21.4-1.21.4-1.0-0.2-0.90.6
Social response proportion0.40.51.2-1.00.8-0.80.80.60.7-0.7-0.8-0.71.10.5-0.80.5-1.10.30.40.40.1
Social responses0.30.41.7-1.00.6-0.50.50.20.3-0.5-0.4-0.40.90.1-0.40.1-1.3-0.3-0.4-0.40.8
Social time4.25.77.5-2.52.4-2.72.72.12.5-2.7-2.7-2.62.42.4-2.62.5-1.62.31.92.0-1.9
Soleus weight0.41.34.8-0.3-0.10.7-0.7-0.2-0.60.70.50.4-0.3-1.00.4-1.1-1.8-1.8-1.7-2.22.1
Bone: stiffness0.20.31.1-0.10.6-0.50.50.80.5-0.2-0.6-0.60.80.4-0.50.3-1.00.01.10.20.3
Tibialis anterior weight0.20.81.90.7-0.70.8-0.8-0.6-0.80.90.70.7-1.1-1.00.7-1.0-0.2-1.2-1.4-1.41.0
Time to tail flick, vehicle, before self-admin0.40.40.80.0-0.70.8-0.8-0.4-0.70.90.70.70.4-0.50.6-0.60.4-0.50.5-0.90.6
Time to tail flick, vehicle, after self-admin1.11.41.91.4-1.41.2-1.2-1.2-1.31.31.31.2-1.1-1.21.3-1.21.1-1.1-0.4-1.11.0
Time to tail flick, test, before self-admin0.90.92.20.6-0.70.9-0.9-0.7-0.90.81.01.0-0.9-1.01.0-1.0-0.2-1.3-1.2-1.51.3
Time to tail flick, test, after self-admin0.50.52.80.1-0.30.4-0.4-0.6-0.50.30.50.5-0.9-0.70.5-0.6-0.3-0.8-1.7-1.00.7
Delta time to tail flick, vehicle, before/after SA0.50.51.61.3-0.70.6-0.6-0.8-0.60.60.70.7-1.2-0.70.7-0.60.9-0.5-0.2-0.00.2
Delta time to tail flick, test, before/after SA0.70.71.1-0.80.8-0.90.90.60.9-0.9-1.0-0.90.50.8-0.90.9-0.40.90.01.0-1.0
Tibia length0.82.37.91.9-1.91.7-1.7-1.7-1.61.71.41.5-1.1-1.31.6-1.22.8-0.5-0.2-0.3-0.4
Ambulatory time before self-admin0.71.11.5-0.91.1-1.11.11.21.2-1.1-1.1-1.00.71.2-1.11.2-0.71.10.51.1-1.2
Ambulatory time after self-admin2.42.85.3-1.01.4-1.71.71.51.7-1.8-1.7-1.70.71.9-1.72.00.02.30.92.3-2.3
Bone: tissue strength1.01.02.7-0.30.7-0.80.81.10.9-0.7-0.9-0.70.81.1-0.71.10.31.31.71.3-1.6
Total heroin consumption0.00.00.2-0.10.0-0.00.0-0.20.0-0.00.0-0.1-0.4-0.0-0.00.00.10.1-0.50.20.1
Bone: trabecular number0.71.23.2-1.11.0-0.70.71.71.1-0.7-0.8-1.01.41.3-1.01.1-1.01.01.80.3-0.5
Bone: trabecular spacing0.50.61.81.2-0.80.6-0.6-1.1-0.70.50.70.8-1.2-0.70.8-0.51.4-0.2-0.90.2-0.1
Bone: trabecular thickness0.20.21.1-0.70.4-0.30.30.70.3-0.3-0.3-0.40.20.2-0.30.1-1.0-0.20.0-0.90.3
Bone: trabecular tissue density0.81.23.8-1.21.4-1.41.41.21.2-1.3-1.3-1.20.80.8-1.00.8-1.90.3-0.10.20.1
Water consumed over 24 hours0.40.61.2-1.10.9-0.70.70.90.8-0.8-0.7-0.71.00.8-0.80.8-0.90.7-0.30.5-0.4
Number of responses in last shaping day0.30.31.3-0.90.3-0.10.10.20.1-0.1-0.1-0.10.4-0.1-0.1-0.2-1.2-0.5-0.6-1.10.9