Hub : Genes

Nars2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr1_160758454_160777979 0.02 0.01 6.4e-03 0.01 0.01 0 0 4.1e-02 3.2e-02 2.8e-01 1.2e-01
2 NAcc gene expression Nars2 0.02 0.01 1.1e-03 0.02 0.02 0.02 0.02 1.2e-03 6.0e-04 1.3e-03 1.6e-03
3 NAcc intron excision ratio chr1_160736012_160758360 0.02 0.01 2.2e-03 0.01 0.01 0 0.01 6.6e-03 1.1e-02 9.5e-02 4.1e-02
4 NAcc mRNA stability Nars2 0.04 0.02 1.4e-06 0.02 0.03 0.03 0.03 1.2e-03 8.0e-06 1.5e-05 5.7e-05
5 Liver gene expression Nars2 0.09 0.05 3.3e-07 0.03 0.05 0.04 0.04 5.4e-04 5.6e-06 4.0e-05 7.5e-05
6 BLA mRNA stability Nars2 0.09 0.05 4.5e-04 0.02 0.07 0 0.06 3.8e-02 1.8e-04 2.8e-01 6.0e-04
7 Adipose gene expression Nars2 0.09 0.06 9.6e-07 0.04 0.05 0.06 0.05 2.2e-05 2.0e-06 1.6e-07 1.3e-06
8 Brain mRNA stability Nars2 0.04 0.03 5.7e-03 0 0 0 0 1.0e-01 1.5e-01 2.8e-01 1.7e-01
9 Liver mRNA stability Nars2 0.04 0.02 8.7e-04 0.01 0.01 0.03 0.01 5.3e-02 7.4e-03 4.7e-04 1.5e-02
10 Adipose mRNA stability Nars2 0.2 0.08 0.0e+00 0.17 0.15 0.16 0.18 3.0e-18 3.5e-16 1.9e-17 2.8e-19

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.20.41.60.20.5-0.6-0.10.7-0.10.80.41.20.5
Area under the delay curve0.50.51.6-1.3-1.00.90.8-0.20.7-0.50.1-0.5-0.4
BMI with tail1.24.311.01.40.8-0.1-3.0-2.2-2.5-1.4-3.3-0.8-2.4
BMI without tail1.85.513.91.20.80.2-3.5-2.5-2.8-1.6-3.70.1-3.1
Body weight2.08.622.61.71.5-0.2-4.6-2.9-4.0-1.0-4.80.7-3.3
Weight adjusted by age0.40.63.50.60.2-1.1-0.10.10.20.7-0.41.9-0.0
Bone surface0.51.02.0-1.4-1.40.91.2-0.01.4-0.10.31.30.1
Bone volume0.30.51.5-1.0-0.90.70.5-0.30.7-0.3-0.11.2-0.4
Breakpoint value in progressive ratio session0.30.30.90.40.6-0.50.20.7-0.10.80.70.20.9
Number of licking bursts1.01.63.81.81.8-1.2-1.8-0.2-1.90.5-0.90.4-0.0
Context. condit. distance diff. score2.22.76.3-1.9-2.01.32.50.32.5-0.31.41.40.9
Locomotion velocity, session 10.91.02.1-0.7-0.60.21.41.01.40.61.40.81.0
Locomotion distance, session 10.40.51.5-0.6-0.90.31.20.11.2-0.10.6-0.50.6
Locomotion velocity, session 20.30.40.9-0.9-0.90.80.70.00.9-0.20.30.2-0.2
Locomotion distance, session 20.40.51.0-0.4-0.41.0-0.4-1.0-0.6-1.0-0.6-0.6-0.7
Locomotion velocity, session 30.60.64.1-0.7-0.30.40.40.70.70.60.42.00.1
Locomotion distance, session 32.22.49.2-1.5-1.10.51.71.11.81.01.33.00.9
Stereotopy head waving bouts, day 32.12.46.42.42.2-1.5-1.50.5-1.50.4-0.1-2.50.3
Stereotopy head waving duration, day 30.70.94.00.10.30.5-0.8-0.7-1.1-1.0-0.5-2.0-0.8
Locomotion velocity, session 70.30.31.0-0.4-0.5-0.10.80.10.70.20.4-1.00.4
Locomotion distance, session 70.40.61.3-0.7-1.10.31.0-0.51.0-0.10.0-1.10.3
Stereotopy head waving bouts, day 70.40.51.7-0.1-0.1-0.11.00.90.80.11.3-0.20.7
Stereotopy head waving duration, day 70.10.20.4-0.5-0.50.30.60.10.6-0.40.5-0.1-0.1
Locomotion velocity, session 83.74.411.0-3.3-2.92.52.8-0.22.4-0.51.31.60.4
Locomotion distance, session 81.11.63.2-1.7-1.81.61.7-0.41.5-0.80.80.80.2
Degree of sensitization distance2.22.213.40.8-0.1-0.2-0.9-1.6-0.8-1.2-1.5-3.7-0.9
Degree of sensitization stereotypy1.61.74.2-1.0-1.00.12.01.12.00.41.81.11.1
Conditioned locomotion0.50.61.7-0.5-0.31.1-0.1-0.8-0.6-1.3-0.1-1.0-0.7
Cocaine response after cond. corrected0.20.31.30.2-0.1-0.60.30.20.60.6-0.01.20.4
Cocaine response after cond. not corrected0.60.71.30.3-0.1-0.80.80.71.01.00.61.11.1
Cocaine response before conditioning1.21.43.00.80.7-1.30.91.50.81.31.4-0.81.7
Saline control response1.72.24.4-1.2-1.11.9-0.9-2.1-0.9-1.7-1.8-0.3-2.0
Bone: connectivity density1.32.16.6-0.20.1-0.71.31.71.31.61.72.61.5
Bone: cortical apparent density0.40.61.40.20.10.6-0.6-0.9-0.9-1.2-0.4-1.0-0.6
Bone: cortical area0.20.31.1-0.3-0.70.4-0.1-1.00.1-0.2-1.1-0.5-0.4
Bone: cortical porosity0.80.82.10.50.6-1.00.31.10.41.50.81.01.2
Bone: cortical porosity1.21.33.00.70.8-1.10.41.50.51.71.11.61.3
Bone: cortical thickness0.10.20.80.60.3-0.5-0.2-0.2-0.20.4-0.4-0.90.3
Bone: cortical thickness1.21.47.8-0.2-1.0-0.41.3-0.11.50.10.3-2.80.7
Bone: cortical tissue density0.30.41.20.20.20.6-0.5-0.8-0.8-1.1-0.3-0.9-0.5
Condit. Reinf. active minus inactive responses0.70.82.70.10.1-0.1-1.2-0.7-0.7-0.2-1.6-0.9-1.4
Condit. Reinf. active-inactive response ratio0.91.03.00.30.2-0.2-1.3-0.8-1.0-0.3-1.7-1.0-1.5
Condit. Reinf. active responses0.40.51.50.30.3-0.2-1.1-0.5-0.8-0.1-1.2-0.6-1.0
Condit. Reinf. inactive responses0.10.21.50.10.1-0.00.00.20.10.20.21.20.2
Incentive salience index mean0.20.20.9-0.1-0.2-0.2-0.5-0.20.00.2-1.0-0.0-0.8
Condit. Reinf. lever presses0.20.31.0-0.7-0.7-0.00.80.41.00.30.40.60.1
Condit. Reinf. active minus inactive responses2.63.37.6-2.1-2.81.90.7-2.41.0-2.0-1.6-1.0-1.7
Condit. Reinf. active-inactive response ratio1.31.53.9-1.6-2.01.30.7-1.50.9-1.3-0.8-0.5-1.0
Condit. Reinf. active responses3.65.09.5-2.4-3.12.40.4-3.00.7-2.5-2.3-1.3-2.3
Condit. Reinf. inactive responses1.31.63.4-0.9-1.11.3-0.7-1.7-0.4-1.5-1.7-0.7-1.8
Condit. Reinf. lever presses7.310.122.0-4.6-4.74.21.6-3.51.5-3.4-1.80.7-2.6
Condit. Reinf. lever reinforcers received3.65.010.9-2.6-3.32.40.7-3.01.1-2.5-2.1-1.1-2.2
Conditioned reinforcement - actives0.91.53.5-0.8-0.80.21.91.01.80.71.70.91.4
Conditioned reinforcement - inactives0.71.02.30.30.9-0.30.31.3-0.11.21.31.51.2
Conditioned locomotion2.93.87.2-0.9-0.7-0.42.62.12.51.82.71.62.3
Patch foraging indifference point 0 sec1.01.94.0-1.8-1.72.00.1-1.70.1-1.4-1.3-0.6-1.5
Patch foraging indifference point AUC0.20.31.6-0.4-0.50.20.2-0.10.5-0.2-0.31.3-0.4
Delay disc. indifference point, 0s delay0.40.51.9-0.2-0.8-0.01.10.21.40.20.6-0.50.6
Delay disc. indifference point, 16s delay1.21.43.0-1.6-1.21.70.3-1.1-0.1-1.6-0.5-1.2-1.1
Delay disc. indifference point, 2s delay0.40.41.1-0.7-0.70.31.00.51.00.50.60.60.4
Delay disc. indifference point, 24s delay0.40.51.0-0.6-0.30.8-0.5-0.8-0.8-0.8-0.8-0.4-1.0
Delay disc. indifference point, 4s delay0.70.71.8-1.3-1.31.00.7-0.50.9-0.5-0.30.2-0.7
Delay disc. indifference point, 8s delay0.60.71.9-1.4-1.21.10.7-0.40.6-0.8-0.1-0.8-0.6
Indifference point function ln k0.20.41.3-1.0-0.61.10.3-0.5-0.1-0.50.1-0.4-0.2
Indifference point function log k0.20.41.3-1.0-0.61.10.3-0.5-0.1-0.50.1-0.4-0.2
Patch foraging total patch changes 0 sec1.01.94.2-1.9-1.82.00.2-1.60.2-1.4-1.2-0.5-1.4
Patch foraging total patch changes 12 sec0.20.20.6-0.2-0.70.20.5-0.40.7-0.4-0.2-0.6-0.1
Patch foraging total patch changes 18 sec0.81.22.5-1.2-1.61.10.4-1.10.8-1.3-0.90.7-1.3
Patch foraging total patch changes 24 sec0.10.20.7-0.2-0.60.10.3-0.20.8-0.2-0.20.5-0.3
Patch foraging total patch changes 6 sec0.30.51.0-0.8-0.40.8-0.6-0.8-0.6-0.3-1.00.2-0.9
Patch foraging time to switch 0 sec1.63.37.12.72.6-2.6-0.81.8-0.91.91.0-0.11.6
Patch foraging water rate 0 sec0.81.74.5-2.1-2.11.71.2-0.91.3-0.9-0.20.4-0.6
Patch foraging water rate 12 sec0.91.94.3-2.1-1.82.00.5-1.50.3-1.7-0.50.3-1.1
Patch foraging water rate 18 sec1.42.14.7-1.6-1.52.2-0.2-1.8-0.2-1.9-1.2-0.1-1.7
Patch foraging water rate 24 sec1.11.54.9-2.0-1.42.20.6-0.90.2-1.30.10.9-0.8
Patch foraging water rate 6 sec0.40.61.6-1.3-1.11.00.8-0.50.5-0.70.30.1-0.2
Seeking ratio, delayed vs. immediate footshock1.41.73.41.11.0-1.70.31.50.51.91.01.71.4
Distance traveled before self-admin0.20.20.60.40.7-0.5-0.70.3-0.70.3-0.30.0-0.2
Distance traveled after self-admin1.82.24.21.42.0-1.7-0.81.9-0.81.90.81.51.1
Extensor digitorum longus weight0.72.86.4-0.5-0.61.5-1.6-2.4-1.5-1.7-2.5-0.7-2.2
Bone: elastic displacement0.91.09.90.20.3-0.2-0.0-0.1-0.40.10.0-3.10.3
Bone: elastic work0.10.20.6-0.10.30.00.20.4-0.20.70.6-0.20.8
Bone: endosteal estimation0.40.81.8-1.1-1.41.00.2-0.90.7-0.7-0.80.8-1.1
Bone: endosteal perimeter1.22.55.2-2.2-2.32.20.7-1.60.9-1.6-0.81.0-1.5
Epididymis fat weight0.51.84.21.91.7-1.0-2.1-0.5-2.00.5-1.3-0.1-0.3
Delta time in closed arm before/after self-admin4.94.57.9-1.5-1.32.4-1.2-2.8-1.3-2.8-2.3-2.0-2.8
Delta time in open arm before/after self-admin0.40.41.1-0.9-1.00.50.9-0.01.1-0.40.0-0.1-0.2
Diff in mean of infusions in LGA sessions1.41.84.71.72.2-1.1-1.60.4-2.20.8-0.1-0.70.5
Delay discount exponential model param0.50.51.51.21.0-0.9-0.70.3-0.60.6-0.00.60.5
Extinction: sum of active levers before priming1.31.42.5-0.8-0.81.3-0.6-1.6-0.7-1.5-1.3-1.4-1.4
Active lever presses in extinction session 60.50.51.50.00.1-0.20.80.80.50.61.20.51.2
Bone: final force0.20.30.7-0.5-0.50.30.7-0.10.50.30.2-0.80.7
Bone: final moment0.20.31.2-0.5-0.60.30.7-0.20.50.10.1-1.10.5
Food consumed during 24 hour testing period1.72.39.0-1.6-0.71.61.31.31.40.61.63.00.5
Glucose0.20.30.8-0.6-0.70.60.4-0.70.2-0.5-0.2-0.9-0.2
Heart weight1.01.53.7-1.1-1.21.5-0.3-1.9-0.5-1.6-1.3-0.6-1.3
Delay discount hyperbolic model param0.50.51.51.21.1-0.8-0.80.2-0.80.5-0.00.60.4
Intermittent access intake day 1-15 change0.40.81.7-1.3-1.01.11.1-0.10.8-0.20.61.20.2
Intermittent access intake escalation0.51.02.0-1.4-1.11.01.40.31.20.20.91.20.5
Intermittent access intake escalation 20.80.91.6-0.3-0.4-0.11.30.81.30.81.21.11.1
Intermitt. access day 1 inactive lever presses0.62.24.11.51.5-1.40.32.00.32.01.61.02.0
Intermitt. access day 15 inactive lever presses0.40.92.51.11.6-0.8-0.90.9-1.01.10.30.50.7
Intermitt. access escalation Index0.40.62.90.00.3-0.30.40.80.20.90.81.70.9
Intermittent access day 1 total infusions0.40.71.7-1.3-1.01.20.8-0.40.5-0.60.3-0.9-0.1
Intermittent access day 15 total infusions1.11.74.1-1.9-1.51.32.00.31.60.11.40.20.8
Intermittent access terminal intake (last 3 days)0.81.12.9-1.1-1.00.81.70.51.50.31.30.41.0
Intermittent access total infusions0.70.82.2-0.9-0.80.61.50.51.30.31.1-0.30.8
Intermittent access day 1 locomotion0.50.61.8-0.6-0.20.41.10.60.60.61.3-0.61.0
Intermittent access day 15 total locomotion0.30.61.6-0.6-0.40.41.20.60.90.61.30.11.1
Intermittent access total locomotion0.30.41.1-0.4-0.20.30.90.40.50.51.1-0.31.0
Intermittent access standard deviation0.10.30.50.10.10.3-0.6-0.5-0.4-0.5-0.7-0.5-0.7
Left kidney weight0.62.96.40.90.60.4-2.5-1.9-2.1-1.3-2.51.2-2.1
Right kidney weight0.62.56.11.00.50.3-2.3-1.8-1.8-1.3-2.50.4-2.0
Cocaine induced anxiety0.50.81.81.21.3-0.5-1.1-0.1-1.40.3-0.3-1.00.2
Post-drug Anxiety0.80.82.10.10.40.3-1.3-0.9-1.5-0.8-1.2-0.2-1.1
Baseline Anxiety1.41.63.4-1.9-1.51.60.2-1.10.2-1.7-0.90.8-1.6
Tail length1.14.211.00.30.10.8-2.8-2.4-2.2-1.6-3.30.4-3.1
Length with tail1.14.812.71.21.00.0-3.4-2.3-3.0-0.8-3.6-0.2-2.5
Length without tail0.61.95.11.61.9-0.8-2.2-0.2-2.30.6-1.3-0.2-0.4
Times rat made contact with spout0.40.51.20.90.90.0-1.1-0.2-1.1-0.4-0.4-0.7-0.4
Lifetime Intake1.01.23.3-1.1-1.10.81.80.61.70.21.30.00.9
Liver weight, left0.50.81.81.31.0-1.2-0.80.2-0.51.0-0.41.30.4
Liver weight, right1.32.36.82.61.8-1.7-2.1-0.5-1.70.3-1.4-0.3-0.3
Locomotor activity1.52.45.3-0.3-0.31.7-1.2-1.8-1.3-2.3-1.5-1.7-1.9
Locomotor testing distance2.23.99.0-0.8-1.32.1-0.9-2.7-0.7-3.0-2.1-1.8-2.5
Locomotor testing rearing1.42.76.00.4-0.41.1-1.6-2.5-1.4-2.1-2.4-0.8-2.1
Locomotion in novel chamber1.92.45.1-0.9-0.60.12.31.61.91.32.11.21.9
Locomotion in novel chamber post-restriction1.42.25.6-2.4-2.01.82.2-0.11.7-0.61.00.50.3
Fecal boli incidents, locomotor time 12.23.29.6-1.2-1.70.22.81.13.10.42.01.21.5
Change in fecal boli incidents, locomotor task1.11.13.80.81.2-0.2-1.7-0.5-2.0-0.2-1.0-0.4-0.7
Time >=10cm from walls, locomotor time 11.21.34.2-1.2-0.90.41.40.81.40.60.92.10.6
Bouts of movement, locomotor time 11.71.95.0-1.7-1.22.2-0.3-1.4-0.4-1.3-1.21.3-1.6
Total resting periods, locomotor time 11.21.44.1-1.6-1.02.0-0.1-1.0-0.4-0.9-0.81.3-1.2
Rest time, locomotor task time 10.40.51.6-1.3-0.91.10.6-0.30.3-0.60.0-0.1-0.3
Distance moved, locomotor task time 10.20.30.90.3-0.1-0.1-0.5-0.7-0.2-0.3-1.00.4-0.7
Vertical activity count, locomotor time 10.10.30.80.0-0.30.2-0.4-0.9-0.3-0.5-0.90.5-0.7
Time >=10cm from walls, locomotor time 20.50.84.0-0.8-0.80.10.80.31.20.50.22.00.0
Bouts of movement, locomotor time 20.20.31.8-0.4-0.30.6-0.1-0.20.1-0.3-0.31.3-0.5
Total resting periods, locomotor time 20.10.21.4-0.4-0.30.50.1-0.00.2-0.2-0.11.2-0.2
Rest time, locomotor task time 20.50.71.31.01.0-0.7-0.01.0-0.10.70.9-0.81.1
Distance moved, locomotor task time 20.40.51.3-0.7-1.10.20.6-0.50.9-0.2-0.41.1-0.4
Vertical activity count, locomotor time 20.40.51.8-0.4-0.90.30.1-0.90.4-0.5-0.81.3-0.7
Light reinforcement 10.61.45.61.61.3-1.0-1.2-0.2-1.20.1-0.6-2.40.0
Light reinforcement 20.50.71.91.00.7-1.40.10.80.11.30.4-0.41.1
Bone: marrow area0.30.71.5-1.0-1.20.90.1-0.90.6-0.7-0.80.8-1.0
Bone: maximum diameter0.71.22.5-1.4-1.61.40.2-1.40.4-0.8-1.20.5-1.1
Bone: maximum force0.30.50.9-0.9-0.70.50.90.20.70.70.50.80.8
Bone: maximum moment0.20.40.8-0.9-0.70.60.90.10.70.60.40.60.7
Mean time between licks in bursts0.20.61.5-0.3-1.2-0.00.5-0.90.9-1.2-0.4-0.0-0.7
Mean num. licks in bursts0.91.32.8-1.7-1.61.51.50.01.5-0.70.6-0.7-0.2
Cd content in liver1.71.83.4-0.2-0.30.8-1.2-1.8-1.2-1.8-1.8-1.3-1.8
Co content in liver1.01.26.4-0.6-1.20.70.6-0.90.8-1.0-0.3-2.5-0.5
Cu content in liver1.72.05.40.1-0.30.5-1.5-1.7-1.1-2.0-2.0-0.1-2.3
Fe content in liver0.60.71.70.50.2-1.00.60.70.71.10.51.31.0
K content in liver0.50.51.20.91.1-0.6-0.41.0-0.30.70.50.70.3
Mg content in liver0.60.65.50.00.30.1-0.10.60.00.30.32.3-0.1
Mn content in liver1.51.73.80.81.1-0.90.62.00.51.41.61.51.5
Na content in liver2.83.07.51.01.0-1.60.82.21.12.31.52.71.8
Rb content in liver0.80.91.9-0.4-0.20.8-0.9-1.2-1.0-1.4-1.0-0.3-1.3
Se content in liver3.03.56.92.32.5-2.6-0.52.5-0.42.11.11.31.5
Sr content in liver1.10.95.7-0.8-0.60.70.80.30.80.30.52.40.5
Zn content in liver1.82.05.3-0.9-1.41.5-0.3-1.90.0-2.3-1.4-0.6-1.9
Bone: minimum diameter0.30.61.8-0.3-0.70.4-0.5-1.00.0-0.6-1.3-0.0-1.2
Time in familiar zone, hab. session 10.00.00.1-0.1-0.10.00.30.20.20.10.3-0.10.2
Time in novel zone, hab. session 10.90.91.90.30.10.0-1.1-1.2-1.1-0.7-1.4-1.4-1.0
Total zone transitions, hab. session 10.10.20.9-0.30.40.6-0.6-0.1-1.00.0-0.20.2-0.2
Total locomotion distance, hab. session 13.24.512.73.63.1-2.7-2.60.6-2.21.4-1.2-0.90.2
Locomotion velocity, hab. session 13.14.412.13.53.1-2.8-2.31.1-1.81.9-0.80.10.5
Time in familiar zone, hab. session 21.01.13.0-1.1-1.11.60.2-1.20.0-1.7-0.5-0.4-1.1
Time in novel zone, hab. session 20.50.51.60.40.1-0.90.40.70.71.30.40.40.9
Total zone transitions, hab. session 20.30.40.9-0.7-0.20.9-0.5-0.6-0.80.0-0.80.6-0.5
Total locomotion distance, hab. session 22.02.75.72.42.0-1.5-2.4-0.3-2.00.8-1.8-1.0-0.5
Locomotion velocity, hab. session 22.33.17.52.42.0-1.4-2.7-0.5-2.30.6-2.1-0.8-0.8
Novel to familiar place preference ratio0.20.30.70.30.5-0.5-0.50.2-0.40.9-0.40.70.1
Novelty place preference0.10.10.30.10.2-0.2-0.40.0-0.30.5-0.40.4-0.1
Time in novel zone, NPP test0.10.10.2-0.3-0.10.1-0.3-0.2-0.20.3-0.50.3-0.2
Total zone transitions, NPP test0.20.31.0-1.0-0.60.80.5-0.10.30.10.10.40.1
Total locomotion distance, NPP test2.02.77.82.81.9-2.7-1.10.8-0.61.7-0.5-1.40.9
Locomotion velocity, NPP test2.63.710.43.22.3-3.1-1.31.0-0.81.8-0.5-1.91.0
Intraocular pressure2.33.28.3-2.9-2.52.32.4-0.42.0-0.81.10.70.3
Delta distance traveled before/after self-admin0.40.41.20.40.8-0.4-0.20.8-0.30.70.61.10.6
Delta ambulatory time before/after self-admin0.10.10.6-0.00.50.1-0.20.4-0.40.30.40.80.3
Parametrial fat weight0.81.94.51.31.6-0.7-2.1-0.3-2.00.7-1.51.6-0.5
Pavlov. Cond. lever latency0.50.62.00.70.80.4-1.1-0.6-1.4-0.4-0.6-0.5-0.2
Pavlov. Cond. magazine entry latency0.50.71.9-1.1-1.40.90.4-1.00.6-0.6-0.80.1-0.7
Pavlov. Cond. change in total contacts1.41.53.7-0.3-0.6-1.01.51.21.91.40.91.41.1
Pavlov. Cond. index score0.40.51.7-0.9-1.30.20.8-0.31.2-0.3-0.20.3-0.4
Pavlov. Cond. latency score0.30.41.4-0.7-1.0-0.10.8-0.01.20.2-0.10.7-0.1
Pavlov. Cond. lever contacts0.40.41.4-0.5-0.7-0.30.70.41.10.40.21.2-0.1
Pavlov. Cond. magazine entry number0.81.02.51.11.6-0.9-0.51.2-0.81.00.80.70.8
Pavlov. Cond. intertrial magazine entries0.60.71.91.31.2-1.4-0.41.1-0.30.60.50.10.5
Pavlov. Cond. lever-magazine prob. diff.0.40.51.5-0.9-1.20.20.9-0.21.2-0.2-0.00.3-0.3
Pavlov. Cond. response bias0.20.30.9-0.7-0.90.30.5-0.30.8-0.3-0.20.2-0.4
Pavlov. Cond. lever latency9.312.628.45.25.3-4.9-2.23.7-2.13.81.5-0.72.5
Pavlov. Cond. magazine entry latency4.14.912.2-3.5-3.43.01.9-2.01.6-2.2-0.30.3-1.1
Pavlov. Cond. change in total contacts5.08.117.5-4.0-4.23.81.4-3.31.3-3.2-1.60.2-2.3
Pavlov. Cond. index score7.610.223.6-4.8-4.94.32.2-3.12.1-3.3-1.21.3-2.1
Pavlov. Cond. latency score7.09.321.5-4.6-4.64.12.1-2.92.0-3.1-1.01.4-1.9
Pavlov. Cond. lever contacts9.513.127.5-5.1-5.25.11.8-4.11.6-4.1-2.00.1-2.9
Pavlov. Cond. magazine entry number7.69.422.94.74.8-4.1-2.92.4-2.73.00.2-0.31.3
Pavlov. Cond. intertrial magazine entries1.01.53.01.71.3-1.3-1.7-0.0-1.10.3-1.2-1.6-0.7
Pavlov. Cond. lever-magazine prob. diff.7.39.722.4-4.6-4.74.22.1-3.12.0-3.2-1.21.3-2.1
Pavlov. Cond. response bias9.913.531.0-5.3-5.65.02.5-3.72.4-4.0-1.40.2-2.5
Time in closed arm before self-admin0.10.10.4-0.3-0.10.30.50.10.20.10.60.20.5
Time in closed arm after self-admin0.30.40.9-0.9-0.40.70.70.30.30.10.80.90.3
Time in open arm before self-admin0.60.62.01.40.9-1.1-0.60.1-0.40.4-0.1-1.20.4
Time in open arm after self-admin0.20.20.60.60.3-0.4-0.5-0.1-0.3-0.2-0.6-0.8-0.3
Bone: periosteal estimation0.40.92.5-1.2-1.60.90.5-1.00.9-0.4-0.90.6-0.7
Bone: periosteal perimeter1.62.74.8-1.6-1.62.2-0.5-2.2-0.5-2.0-1.70.2-2.1
Bone: post-yield work0.40.74.7-0.10.4-0.1-0.10.6-0.11.10.22.20.4
Progressive ratio test 1 active lever presses0.30.31.1-0.5-0.00.30.70.60.30.41.1-0.20.8
Progressive ratio test 1 breakpoint0.30.41.2-0.5-0.10.40.80.60.40.41.1-0.30.8
Progressive ratio test 1 inactive lever presses0.40.61.30.50.9-0.40.11.1-0.01.01.10.51.1
Progressive ratio test 2 active lever presses0.50.61.7-0.8-0.90.21.30.31.30.30.8-0.10.6
Progressive ratio test 2 breakpoint0.60.72.0-0.8-0.90.11.40.41.40.40.9-0.10.7
Progressive ratio test 2 inactive lever presses0.10.10.2-0.3-0.30.10.5-0.00.30.10.4-0.30.4
Incentive Sensitization - Responses0.20.31.0-0.8-1.00.30.7-0.30.9-0.2-0.10.2-0.1
Incentive Sensitization - Breakpoint0.20.30.8-0.6-0.80.10.7-0.10.90.00.00.30.0
Sum of active levers in priming session hrs 5-60.30.30.70.80.7-0.5-0.6-0.2-0.80.1-0.2-0.80.2
Progressive ratio1.01.53.2-1.8-1.51.41.40.11.5-0.40.61.7-0.1
Food seeking constrained by brief footshock1.61.94.0-0.8-1.11.6-0.7-1.8-0.3-1.9-1.8-0.3-2.0
Seeking ratio, punishment vs. effort0.91.23.41.81.2-1.4-1.5-0.3-1.10.2-1.1-0.8-0.4
Retroperitoneal fat weight2.912.332.13.53.1-1.2-5.7-2.6-5.2-0.9-4.7-1.4-3.0
Reaction time number correct0.40.86.30.20.30.3-0.3-0.2-0.7-0.60.2-2.5-0.2
Reaction time mean minus median0.71.98.4-0.8-0.91.1-0.3-1.5-0.3-1.3-1.2-2.9-1.4
Reaction time mean minus median AUC0.61.57.6-0.7-0.90.9-0.0-1.3-0.2-1.3-0.7-2.8-0.9
Reaction time num false alarms0.30.51.50.70.9-0.5-1.20.0-1.00.1-0.70.0-0.5
Reaction time num false alarms AUC0.10.10.30.20.5-0.2-0.50.4-0.30.20.00.1-0.2
Reaction time trials correct on left0.40.86.30.20.30.3-0.3-0.2-0.7-0.60.2-2.5-0.2
Reaction time trials on left0.40.86.60.20.30.3-0.3-0.3-0.7-0.60.2-2.6-0.2
Reaction time mean0.20.40.91.00.6-0.9-0.5-0.1-0.40.3-0.6-0.70.1
Reaction time mean AUC0.20.30.80.80.6-0.9-0.40.1-0.40.5-0.4-0.40.2
Median of all reaction times0.40.62.11.30.9-1.4-0.30.5-0.10.9-0.10.40.7
Reaction time omissions0.71.05.30.0-0.50.1-0.5-1.3-0.3-0.5-1.3-2.3-0.8
Reaction time false alarm rate0.40.53.20.30.4-0.6-0.10.70.20.70.11.80.3
Reaction time premature initiation rate0.91.24.10.70.2-0.4-1.5-1.1-0.9-0.6-2.0-0.5-1.6
Reaction time premature initiations0.71.22.70.60.2-0.3-1.4-1.1-1.0-0.8-1.6-1.5-1.4
Std. dev. reaction times0.81.56.1-0.1-0.60.5-0.7-1.4-0.5-1.2-1.5-2.5-1.4
Reaction time trials completed0.40.86.60.20.30.3-0.3-0.3-0.7-0.60.2-2.6-0.2
Reaction time trials AUC0.50.96.90.20.30.3-0.5-0.5-0.7-0.7-0.1-2.6-0.4
Run reversals in cocaine runway, females1.91.95.00.0-0.10.7-1.8-1.6-1.3-1.3-2.20.2-2.2
Run reversals in cocaine runway, males1.81.84.0-1.9-1.72.00.8-1.20.3-1.7-0.1-1.2-0.8
Latency to leave start box in cocaine runway2.63.07.82.52.2-2.8-1.01.7-0.52.10.51.01.2
Latency to leave start box in cocaine runway, F1.92.26.72.51.9-2.6-0.91.2-0.31.50.30.10.8
Latency to leave start box in cocaine runway, M1.41.33.10.81.1-1.3-0.01.40.01.70.71.81.0
Std. dev. time between licks in bursts0.60.91.60.80.3-0.2-1.2-0.8-0.8-0.7-1.21.3-1.2
Total sessions with >9 infusions1.11.33.8-1.0-1.20.71.80.62.00.01.30.40.8
Short access day 1 total inactive lever presses0.40.51.3-1.1-1.01.00.6-0.30.6-0.6-0.00.5-0.4
Short access day 10 total inactive lever presses0.51.34.11.31.7-0.4-1.8-0.1-2.00.1-0.7-0.8-0.3
Short access day 1 total infusions0.60.82.5-1.0-1.30.61.30.11.6-0.10.50.80.2
Short access day 10 total infusions0.91.23.2-1.3-1.51.11.60.21.8-0.20.80.10.3
Short access total infusions1.11.53.8-1.4-1.51.11.90.21.9-0.21.10.50.5
Short access day 1 locomotion1.31.63.6-1.9-1.81.51.8-0.21.5-0.31.0-0.10.4
Short access day 10 total locomotion0.40.72.4-1.2-1.11.50.7-0.40.6-0.50.2-0.6-0.3
Short access total locomotion0.50.61.7-0.4-0.30.51.10.71.00.61.3-0.21.0
One hour access (0.3 mA shock)0.60.71.4-1.0-1.21.10.8-0.80.7-1.0-0.0-0.9-0.4
Compulsive drug intake0.91.12.11.01.3-1.1-0.31.4-0.31.40.61.30.8
One hour access (shock baseline)1.01.63.6-1.6-1.91.41.8-0.61.6-1.00.7-0.80.1
Social response proportion1.41.64.32.12.0-1.5-1.40.6-1.30.9-0.10.60.5
Social responses1.41.84.21.21.0-0.1-2.0-1.4-2.0-0.8-1.6-0.8-1.2
Social time1.31.73.71.91.9-1.6-1.30.8-1.11.4-0.11.20.7
Soleus weight0.82.45.00.70.60.4-2.2-1.5-1.9-0.9-2.2-1.4-1.9
Bone: stiffness0.20.31.20.20.4-0.4-0.10.2-0.30.90.01.10.8
Tibialis anterior weight0.31.12.80.20.30.3-1.5-1.3-1.4-0.6-1.7-0.5-1.3
Time to tail flick, vehicle, before self-admin0.20.20.4-0.3-0.40.6-0.1-0.6-0.0-0.6-0.5-0.2-0.5
Time to tail flick, vehicle, after self-admin1.01.32.6-1.5-1.61.60.6-1.20.6-1.5-0.5-0.1-1.0
Time to tail flick, test, before self-admin1.01.02.0-1.4-1.11.40.1-0.70.3-1.0-0.81.0-1.3
Time to tail flick, test, after self-admin1.41.53.1-0.8-1.31.4-0.1-1.50.1-1.8-1.1-1.3-1.4
Delta time to tail flick, vehicle, before/after SA0.50.51.2-1.1-1.10.71.0-0.30.9-0.50.4-0.30.0
Delta time to tail flick, test, before/after SA0.60.73.21.10.8-0.7-0.5-0.1-0.70.1-0.0-1.80.4
Tibia length0.71.87.1-1.2-1.00.71.40.71.61.20.82.71.0
Ambulatory time before self-admin0.20.20.60.10.6-0.5-0.20.8-0.20.80.30.40.3
Ambulatory time after self-admin1.41.63.70.61.6-1.0-0.51.8-0.61.71.01.91.0
Bone: tissue strength2.02.04.71.11.7-1.5-0.31.5-0.82.20.91.31.8
Total heroin consumption0.30.31.70.20.00.3-0.3-0.7-0.5-0.6-0.3-1.3-0.2
Bone: trabecular number0.20.40.70.40.7-0.6-0.00.8-0.30.80.70.70.7
Bone: trabecular spacing0.30.41.3-0.3-0.7-0.11.00.11.1-0.20.5-1.00.4
Bone: trabecular thickness1.62.04.0-0.4-0.11.1-1.7-1.8-1.8-1.3-1.9-0.4-2.0
Bone: trabecular tissue density2.53.78.61.41.40.1-2.6-1.6-2.9-1.1-2.0-2.9-1.4
Water consumed over 24 hours0.30.31.10.61.0-0.0-0.90.3-1.00.2-0.10.1-0.2
Number of responses in last shaping day1.11.24.22.11.4-1.8-0.90.4-0.50.9-0.2-0.00.5