Hub : Genes

Nars2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr1_151347225_151366752 0.03 0.02 1.2e-03 0.01 0.02 0.01 0.01 3.7e-02 2.3e-03 2.4e-02 1.3e-02
2 NAcc intron excision ratio chr1_151324782_151347131 0.04 0.02 4.0e-04 0.01 0.03 0.02 0.02 1.2e-02 5.1e-04 1.3e-03 3.1e-03
3 BLA mRNA stability Nars2 0.06 0.04 5.5e-03 0.02 0.04 0.05 0.03 2.3e-02 3.5e-03 1.6e-03 8.2e-03
4 Adipose gene expression Nars2 0.09 0.05 2.1e-06 0.03 0.05 0.06 0.06 1.1e-04 2.3e-06 3.2e-07 7.3e-07
5 Liver gene expression Nars2 0.1 0.05 1.8e-07 0.03 0.05 0.04 0.04 1.4e-04 3.4e-06 4.9e-05 2.2e-05
6 Adipose mRNA stability Nars2 0.12 0.06 4.7e-12 0.11 0.1 0.12 0.12 5.1e-12 4.3e-11 6.7e-13 1.4e-13
7 Liver mRNA stability Nars2 0.04 0.02 3.5e-04 0.03 0.02 0.01 0.02 6.0e-04 3.7e-03 2.3e-02 2.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.10.4-0.00.1-0.4-0.20.70.2-0.6
Area under the delay curve0.60.71.7-1.31.3-0.80.6-0.4-0.40.1
BMI with tail0.82.76.40.8-0.82.50.7-1.6-1.82.2
BMI without tail3.67.418.22.0-2.14.30.9-1.9-2.73.7
Body weight2.29.219.21.2-1.24.41.6-3.0-3.64.2
Weight adjusted by age0.20.20.50.4-0.40.7-0.4-0.20.40.6
Bone surface0.61.12.4-1.51.5-1.50.4-0.1-0.2-0.6
Bone volume0.40.71.5-1.21.2-1.00.8-0.4-0.7-0.0
Breakpoint value in progressive ratio session0.30.30.6-0.20.2-0.6-0.50.40.8-0.7
Number of licking bursts1.21.43.21.8-1.71.8-0.4-0.1-0.10.6
Context. condit. distance diff. score2.22.78.6-1.91.9-2.90.60.10.4-1.5
Locomotion velocity, session 11.01.01.8-0.80.8-1.1-0.71.01.2-1.3
Locomotion distance, session 10.30.40.8-0.60.5-0.9-0.30.10.7-0.8
Locomotion velocity, session 20.30.30.9-1.00.9-0.40.00.0-0.0-0.3
Locomotion distance, session 20.30.41.0-0.40.40.80.5-1.0-0.70.7
Locomotion velocity, session 30.20.30.5-0.70.7-0.6-0.20.60.1-0.3
Locomotion distance, session 31.41.53.2-1.61.6-1.8-0.20.80.6-1.2
Stereotopy head waving bouts, day 32.02.45.92.4-2.41.8-1.00.80.50.1
Stereotopy head waving duration, day 30.20.20.40.1-0.10.60.5-0.6-0.60.6
Locomotion velocity, session 70.20.20.3-0.50.5-0.4-0.2-0.10.5-0.5
Locomotion distance, session 70.30.30.6-0.80.8-0.70.2-0.70.2-0.2
Stereotopy head waving bouts, day 70.60.71.40.2-0.2-0.4-0.90.91.2-1.1
Stereotopy head waving duration, day 70.10.10.3-0.40.4-0.60.10.20.2-0.3
Locomotion velocity, session 84.14.911.8-3.43.4-2.80.9-0.50.1-1.2
Locomotion distance, session 81.01.53.2-1.71.7-1.80.8-0.5-0.2-0.7
Degree of sensitization distance1.01.02.20.9-0.90.90.7-1.5-0.71.3
Degree of sensitization stereotypy1.51.62.9-1.11.1-1.7-0.71.01.3-1.7
Conditioned locomotion0.50.61.6-0.50.6-0.41.2-0.9-0.80.3
Cocaine response after cond. corrected0.10.10.60.3-0.3-0.80.10.10.2-0.2
Cocaine response after cond. not corrected0.40.51.20.3-0.3-1.1-0.40.60.7-0.9
Cocaine response before conditioning1.41.73.40.8-0.8-0.3-1.61.61.8-1.5
Saline control response2.63.56.6-1.21.20.12.4-2.2-2.62.0
Bone: connectivity density1.01.53.2-0.50.5-1.4-1.01.61.3-1.8
Bone: cortical apparent density0.60.82.00.3-0.30.21.4-1.1-1.20.9
Bone: cortical area0.20.41.1-0.60.5-0.20.5-1.0-0.40.6
Bone: cortical porosity0.40.40.80.4-0.4-0.3-0.80.90.8-0.7
Bone: cortical porosity1.01.02.10.7-0.7-0.2-1.31.41.2-1.0
Bone: cortical thickness0.10.10.20.5-0.50.1-0.4-0.20.40.0
Bone: cortical thickness0.70.83.7-0.50.5-1.9-0.1-0.10.9-1.0
Bone: cortical tissue density0.50.71.80.3-0.30.21.3-0.9-1.20.8
Condit. Reinf. active minus inactive responses0.70.82.60.1-0.20.70.7-0.7-1.11.6
Condit. Reinf. active-inactive response ratio0.91.02.70.3-0.30.41.2-0.8-1.41.6
Condit. Reinf. active responses0.40.51.60.3-0.40.90.3-0.5-0.71.3
Condit. Reinf. inactive responses0.10.10.20.1-0.10.5-0.50.20.3-0.0
Incentive salience index mean0.20.20.9-0.10.10.30.3-0.3-0.41.0
Condit. Reinf. lever presses0.20.30.7-0.90.8-0.4-0.20.20.5-0.2
Condit. Reinf. active minus inactive responses2.93.65.9-2.01.9-1.42.4-2.4-1.61.4
Condit. Reinf. active-inactive response ratio1.61.72.6-1.61.6-1.21.4-1.5-0.70.6
Condit. Reinf. active responses3.95.49.6-2.22.2-1.02.8-3.1-2.32.1
Condit. Reinf. inactive responses1.72.14.1-0.80.70.71.6-1.8-2.01.9
Condit. Reinf. lever presses8.711.819.0-4.44.3-2.63.9-3.6-2.91.4
Condit. Reinf. lever reinforcers received3.95.49.0-2.42.3-1.42.8-3.0-2.21.8
Conditioned reinforcement - actives3.33.36.9-0.90.9-2.6-1.11.91.8-2.5
Conditioned reinforcement - inactives0.91.02.90.5-0.50.9-1.71.01.2-0.8
Conditioned locomotion2.73.26.2-0.90.9-2.2-1.42.02.0-2.5
Patch foraging indifference point 0 sec1.62.63.6-1.81.8-0.61.9-1.9-1.71.2
Patch foraging indifference point AUC0.00.00.1-0.30.30.1-0.30.10.10.1
Delay disc. indifference point, 0s delay0.10.10.2-0.10.1-0.2-0.40.10.4-0.4
Delay disc. indifference point, 16s delay1.61.62.7-1.51.6-0.71.6-1.2-1.40.5
Delay disc. indifference point, 2s delay0.30.30.6-0.80.8-0.4-0.60.30.5-0.5
Delay disc. indifference point, 24s delay0.50.50.8-0.70.8-0.20.9-0.7-0.60.6
Delay disc. indifference point, 4s delay0.50.51.5-1.21.2-0.20.4-0.6-0.50.4
Delay disc. indifference point, 8s delay1.31.32.4-1.51.5-1.31.3-0.6-0.80.1
Indifference point function ln k0.50.61.2-1.11.1-0.60.9-0.6-0.7-0.1
Indifference point function log k0.50.61.2-1.11.1-0.60.9-0.6-0.7-0.1
Patch foraging total patch changes 0 sec1.62.73.8-1.81.8-0.82.0-1.8-1.71.1
Patch foraging total patch changes 12 sec0.00.10.1-0.30.2-0.40.2-0.4-0.1-0.1
Patch foraging total patch changes 18 sec0.81.01.5-1.21.1-0.61.2-1.0-1.00.7
Patch foraging total patch changes 24 sec0.10.20.6-0.30.2-0.70.5-0.1-0.40.1
Patch foraging total patch changes 6 sec0.40.61.0-0.80.80.20.8-0.8-1.00.7
Patch foraging time to switch 0 sec2.84.36.92.6-2.61.6-2.41.91.9-1.0
Patch foraging water rate 0 sec1.42.24.3-2.12.1-1.71.5-1.0-0.80.3
Patch foraging water rate 12 sec2.13.35.0-2.22.2-1.12.2-1.7-1.70.8
Patch foraging water rate 18 sec2.53.46.6-1.61.6-0.62.6-1.9-2.41.4
Patch foraging water rate 24 sec1.31.94.2-2.02.0-0.81.4-1.0-1.20.1
Patch foraging water rate 6 sec0.71.02.0-1.41.4-1.11.1-0.6-0.50.0
Seeking ratio, delayed vs. immediate footshock0.80.91.70.7-0.70.2-1.31.21.1-0.8
Distance traveled before self-admin0.10.10.10.2-0.20.4-0.30.30.20.2
Distance traveled after self-admin0.70.81.50.7-0.61.1-1.21.20.6-0.2
Extensor digitorum longus weight0.62.45.0-0.50.51.01.5-2.2-2.02.0
Bone: elastic displacement0.10.10.30.3-0.30.3-0.4-0.10.5-0.2
Bone: elastic work0.30.31.1-0.20.3-0.1-0.70.40.6-1.1
Bone: endosteal estimation0.30.71.2-1.11.0-0.30.8-0.8-0.70.8
Bone: endosteal perimeter1.22.44.7-2.22.1-0.71.5-1.6-1.20.8
Epididymis fat weight1.32.96.32.3-2.42.5-0.3-0.5-0.71.5
Delta time in closed arm before/after self-admin8.17.916.1-1.51.50.04.0-3.6-3.82.7
Delta time in open arm before/after self-admin0.30.30.4-0.50.5-0.6-0.50.60.6-0.6
Diff in mean of infusions in LGA sessions1.01.13.21.4-1.31.8-0.2-0.2-0.20.7
Delay discount exponential model param0.70.71.71.3-1.30.8-0.80.50.4-0.1
Extinction: sum of active levers before priming0.60.61.3-0.50.5-0.31.1-1.0-1.00.8
Active lever presses in extinction session 60.70.71.4-0.10.1-1.0-0.80.81.1-1.2
Bone: final force0.20.30.6-0.60.6-0.80.0-0.30.2-0.6
Bone: final moment0.20.30.6-0.60.6-0.80.1-0.40.1-0.5
Food consumed during 24 hour testing period1.11.32.8-1.71.6-1.3-0.11.2-0.0-1.0
Glucose0.40.61.1-1.01.1-0.60.8-0.7-0.5-0.1
Heart weight0.81.11.6-1.21.1-1.21.2-1.1-0.70.2
Delay discount hyperbolic model param0.60.61.61.3-1.30.8-0.50.40.2-0.0
Intermittent access intake day 1-15 change1.11.12.0-1.41.4-0.7-1.00.41.0-1.1
Intermittent access intake escalation1.11.12.6-1.61.6-0.9-0.50.10.7-0.9
Intermittent access intake escalation 20.40.41.0-0.20.1-0.4-0.90.61.0-0.8
Intermitt. access day 1 inactive lever presses1.71.93.41.4-1.50.7-1.81.41.3-1.1
Intermitt. access day 15 inactive lever presses0.40.41.3-0.00.01.2-1.10.00.5-0.2
Intermitt. access escalation Index0.40.31.30.2-0.21.1-0.90.20.3-0.0
Intermittent access day 1 total infusions0.50.61.4-1.01.0-1.20.8-0.3-0.4-0.2
Intermittent access day 15 total infusions1.51.73.4-1.81.8-1.80.00.10.5-1.3
Intermittent access terminal intake (last 3 days)0.80.81.8-0.90.9-1.3-0.40.50.7-1.2
Intermittent access total infusions0.80.91.9-0.50.5-1.4-0.60.90.9-1.3
Intermittent access day 1 locomotion1.31.43.10.1-0.1-1.2-1.01.51.4-1.7
Intermittent access day 15 total locomotion0.50.61.7-0.80.8-1.30.00.00.5-0.9
Intermittent access total locomotion0.40.51.3-0.20.2-1.1-0.30.50.6-1.0
Intermittent access standard deviation0.70.71.70.5-0.50.2-1.30.91.1-0.7
Left kidney weight0.82.34.6-0.10.00.81.7-1.9-2.02.1
Right kidney weight0.92.54.60.2-0.31.11.8-2.0-2.12.0
Cocaine induced anxiety0.40.51.11.0-0.91.1-0.2-0.3-0.10.3
Post-drug Anxiety0.30.40.70.00.00.20.8-0.8-0.80.7
Baseline Anxiety1.61.73.5-1.91.8-1.61.2-0.4-0.70.2
Tail length1.95.712.90.7-0.82.71.9-2.4-3.13.6
Length with tail1.66.012.90.8-0.93.21.6-2.4-3.03.6
Length without tail0.20.30.6-0.20.30.80.4-0.7-0.70.7
Times rat made contact with spout0.50.51.01.0-0.91.00.3-0.1-0.60.7
Lifetime Intake0.80.92.4-0.80.7-1.5-0.30.80.7-1.2
Liver weight, left0.71.23.50.5-0.51.90.4-0.9-1.31.2
Liver weight, right2.74.510.73.0-3.03.3-0.9-0.1-0.41.5
Locomotor activity1.52.45.6-0.00.00.52.3-1.8-2.41.6
Locomotor testing distance2.13.56.8-0.80.70.12.6-2.5-2.61.9
Locomotor testing rearing1.92.95.20.4-0.51.51.7-2.3-2.22.2
Locomotion in novel chamber1.72.13.5-0.91.0-1.4-1.41.41.9-1.9
Locomotion in novel chamber post-restriction2.32.86.3-2.32.3-2.50.30.20.6-1.5
Fecal boli incidents, locomotor time 12.42.67.6-1.31.2-2.8-0.60.81.6-1.9
Change in fecal boli incidents, locomotor task0.90.92.00.9-0.81.40.5-0.5-0.81.2
Time >=10cm from walls, locomotor time 10.80.81.3-1.11.1-1.2-0.40.70.7-0.8
Bouts of movement, locomotor time 11.61.72.7-1.61.60.50.9-1.4-1.51.1
Total resting periods, locomotor time 11.11.22.6-1.61.60.20.6-1.0-1.10.7
Rest time, locomotor task time 10.40.51.5-1.21.2-0.60.2-0.3-0.10.1
Distance moved, locomotor task time 10.20.20.30.4-0.50.40.4-0.5-0.50.5
Vertical activity count, locomotor time 10.30.40.90.2-0.20.10.9-0.7-0.90.4
Time >=10cm from walls, locomotor time 20.30.30.5-0.70.7-0.6-0.50.50.5-0.2
Bouts of movement, locomotor time 20.20.20.5-0.30.30.7-0.4-0.2-0.10.5
Total resting periods, locomotor time 20.10.10.2-0.30.30.4-0.3-0.1-0.10.3
Rest time, locomotor task time 20.80.91.51.1-1.10.4-1.21.01.0-0.7
Distance moved, locomotor task time 20.30.40.7-0.70.6-0.90.8-0.5-0.50.0
Vertical activity count, locomotor time 20.40.41.0-0.30.2-0.41.0-0.8-0.80.4
Light reinforcement 10.81.53.71.9-1.91.5-0.70.10.20.4
Light reinforcement 20.71.02.01.0-1.00.0-1.20.91.4-0.6
Bone: marrow area0.30.61.0-1.00.9-0.20.7-0.8-0.70.8
Bone: maximum diameter0.81.52.9-1.71.7-0.41.0-1.5-1.00.8
Bone: maximum force0.40.71.4-1.21.2-1.1-0.0-0.10.3-0.8
Bone: maximum moment0.40.71.5-1.21.2-1.00.0-0.20.2-0.8
Mean time between licks in bursts0.40.51.2-0.40.4-0.61.1-1.0-0.60.7
Mean num. licks in bursts1.01.22.7-1.61.6-1.50.7-0.1-0.2-0.3
Cd content in liver0.20.30.60.8-0.80.30.4-0.3-0.30.5
Co content in liver0.50.61.0-0.90.8-0.70.8-1.0-0.30.6
Cu content in liver1.92.24.9-0.40.4-0.12.2-1.7-2.11.7
Fe content in liver0.40.41.0-0.10.0-1.0-0.50.51.0-0.8
K content in liver0.50.50.90.9-0.90.9-0.30.7-0.10.2
Mg content in liver0.10.10.4-0.20.2-0.10.40.2-0.60.2
Mn content in liver1.01.12.90.7-0.7-0.1-1.11.71.0-1.3
Na content in liver2.62.75.81.1-1.1-0.3-2.02.41.9-1.7
Rb content in liver2.12.74.9-1.41.4-0.22.2-1.9-2.01.5
Se content in liver2.22.76.11.9-1.90.4-1.52.51.3-1.1
Sr content in liver0.50.41.0-1.01.0-0.7-0.20.20.2-0.7
Zn content in liver1.21.32.6-1.01.0-1.11.6-1.3-1.00.7
Bone: minimum diameter0.30.51.7-0.30.30.60.5-1.0-0.61.3
Time in familiar zone, hab. session 10.00.00.1-0.10.1-0.2-0.00.10.1-0.3
Time in novel zone, hab. session 10.70.71.70.4-0.40.70.7-1.1-0.81.3
Total zone transitions, hab. session 10.10.20.8-0.20.30.9-0.6-0.00.00.0
Total locomotion distance, hab. session 14.56.413.13.6-3.63.5-2.10.80.81.1
Locomotion velocity, hab. session 14.56.412.33.5-3.53.3-2.51.31.10.7
Time in familiar zone, hab. session 21.21.32.6-1.11.1-0.41.6-1.2-1.30.8
Time in novel zone, hab. session 20.50.51.10.4-0.4-0.3-1.10.71.0-0.7
Total zone transitions, hab. session 20.30.30.7-0.70.70.8-0.3-0.6-0.20.4
Total locomotion distance, hab. session 22.73.58.82.4-2.53.0-1.2-0.10.01.6
Locomotion velocity, hab. session 22.94.011.02.4-2.53.3-1.1-0.3-0.31.9
Novel to familiar place preference ratio0.40.41.20.3-0.30.9-1.10.30.60.1
Novelty place preference0.20.20.60.1-0.10.8-0.80.10.40.2
Time in novel zone, NPP test0.10.10.4-0.20.20.6-0.6-0.20.30.3
Total zone transitions, NPP test0.30.41.1-1.01.0-0.2-0.3-0.10.4-0.4
Total locomotion distance, NPP test2.83.98.02.8-2.81.9-2.10.91.50.3
Locomotion velocity, NPP test3.54.910.63.2-3.32.1-2.31.21.60.2
Intraocular pressure2.63.69.3-3.03.1-2.00.8-0.7-0.2-1.0
Delta distance traveled before/after self-admin0.20.20.80.1-0.10.90.0-0.1-0.70.2
Delta ambulatory time before/after self-admin0.20.20.7-0.30.40.50.4-0.3-0.90.1
Parametrial fat weight1.12.17.11.4-1.42.7-0.4-0.6-0.81.7
Pavlov. Cond. lever latency0.30.41.10.7-0.61.00.0-0.5-0.60.3
Pavlov. Cond. magazine entry latency0.60.81.3-0.90.9-1.11.1-0.8-0.80.5
Pavlov. Cond. change in total contacts0.91.02.9-0.40.3-1.7-0.51.11.2-1.0
Pavlov. Cond. index score0.50.71.5-1.00.9-1.21.0-0.4-0.30.3
Pavlov. Cond. latency score0.30.41.2-0.80.7-1.10.5-0.10.00.1
Pavlov. Cond. lever contacts0.20.20.7-0.60.6-0.80.20.30.2-0.0
Pavlov. Cond. magazine entry number1.31.62.91.3-1.21.4-1.71.31.0-0.6
Pavlov. Cond. intertrial magazine entries0.70.81.41.2-1.20.7-0.81.10.8-0.2
Pavlov. Cond. lever-magazine prob. diff.0.50.61.8-0.90.9-1.30.9-0.2-0.20.1
Pavlov. Cond. response bias0.30.40.8-0.50.5-0.90.9-0.3-0.40.3
Pavlov. Cond. lever latency12.216.425.95.1-5.13.3-4.64.13.4-1.4
Pavlov. Cond. magazine entry latency5.36.110.6-3.23.3-2.82.6-2.2-1.5-0.0
Pavlov. Cond. change in total contacts6.99.514.6-3.83.8-2.53.5-3.3-2.61.1
Pavlov. Cond. index score9.712.520.9-4.64.6-3.43.9-3.4-2.70.8
Pavlov. Cond. latency score9.211.419.5-4.44.4-3.23.7-3.2-2.50.7
Pavlov. Cond. lever contacts11.916.324.1-4.94.9-3.04.7-4.3-3.61.6
Pavlov. Cond. magazine entry number9.211.220.74.6-4.54.0-3.32.71.70.2
Pavlov. Cond. intertrial magazine entries1.41.94.21.8-1.82.0-0.40.1-0.41.5
Pavlov. Cond. lever-magazine prob. diff.9.011.519.2-4.44.4-3.13.7-3.3-2.60.8
Pavlov. Cond. response bias11.315.425.1-5.05.0-3.64.4-3.9-3.11.0
Time in closed arm before self-admin0.40.51.3-0.30.3-0.5-0.70.80.7-1.1
Time in closed arm after self-admin0.80.81.8-1.31.4-0.90.5-0.1-0.4-0.8
Time in open arm before self-admin0.60.61.11.1-1.00.80.4-0.6-0.40.9
Time in open arm after self-admin0.20.20.50.6-0.60.7-0.1-0.1-0.10.7
Bone: periosteal estimation0.40.91.9-1.41.3-0.70.7-1.1-0.50.6
Bone: periosteal perimeter1.93.24.8-1.81.8-0.12.1-2.2-2.01.5
Bone: post-yield work0.20.30.6-0.40.4-0.1-0.70.80.6-0.6
Progressive ratio test 1 active lever presses0.30.30.80.3-0.3-0.0-0.70.90.6-0.7
Progressive ratio test 1 breakpoint0.60.61.40.5-0.5-0.2-0.91.20.8-1.0
Progressive ratio test 1 inactive lever presses0.20.20.60.1-0.10.1-0.70.60.5-0.4
Progressive ratio test 2 active lever presses0.30.30.9-0.70.6-1.00.00.00.3-0.5
Progressive ratio test 2 breakpoint0.10.20.4-0.40.4-0.6-0.20.20.4-0.4
Progressive ratio test 2 inactive lever presses0.10.20.3-0.50.4-0.5-0.2-0.00.4-0.5
Incentive Sensitization - Responses0.30.30.7-0.90.8-0.50.2-0.4-0.10.0
Incentive Sensitization - Breakpoint0.20.20.6-0.80.7-0.4-0.0-0.20.1-0.1
Sum of active levers in priming session hrs 5-60.20.20.40.6-0.60.60.2-0.4-0.30.4
Progressive ratio1.01.13.0-1.71.7-1.20.4-0.2-0.2-0.3
Food seeking constrained by brief footshock1.41.73.3-0.70.60.41.5-1.7-1.81.6
Seeking ratio, punishment vs. effort1.01.23.01.7-1.71.3-0.1-0.1-0.30.9
Retroperitoneal fat weight3.812.528.93.3-3.35.41.2-2.6-3.14.4
Reaction time number correct0.00.00.10.2-0.20.20.3-0.2-0.2-0.2
Reaction time mean minus median0.91.22.3-0.50.60.31.3-1.5-1.21.4
Reaction time mean minus median AUC0.60.81.8-0.60.6-0.21.2-1.4-0.80.9
Reaction time num false alarms0.30.41.40.7-0.81.2-0.50.2-0.20.5
Reaction time num false alarms AUC0.10.20.50.3-0.30.6-0.70.60.2-0.2
Reaction time trials correct on left0.00.00.10.2-0.20.20.3-0.2-0.2-0.2
Reaction time trials on left0.00.00.10.2-0.20.20.2-0.2-0.2-0.2
Reaction time mean0.30.51.01.0-1.00.7-0.5-0.10.50.5
Reaction time mean AUC0.30.40.80.9-0.90.5-0.50.00.60.3
Median of all reaction times0.60.91.51.2-1.20.4-1.10.61.1-0.2
Reaction time omissions0.50.61.90.1-0.10.30.9-1.4-0.71.0
Reaction time false alarm rate0.20.31.00.3-0.30.3-1.00.80.6-0.3
Reaction time premature initiation rate1.31.74.50.7-0.81.31.0-1.1-1.52.1
Reaction time premature initiations0.91.32.90.6-0.71.11.0-1.0-1.41.7
Std. dev. reaction times0.81.12.60.0-0.00.51.2-1.5-1.21.6
Reaction time trials completed0.00.00.10.2-0.20.20.2-0.2-0.2-0.2
Reaction time trials AUC0.10.10.20.3-0.20.30.4-0.4-0.40.1
Run reversals in cocaine runway, females2.92.86.5-0.0-0.01.11.9-1.8-2.32.6
Run reversals in cocaine runway, males1.81.73.7-1.91.9-1.01.2-1.2-0.8-0.0
Latency to leave start box in cocaine runway1.71.94.32.0-2.10.4-1.01.60.9-0.4
Latency to leave start box in cocaine runway, F1.51.63.91.9-2.00.2-0.91.40.8-0.4
Latency to leave start box in cocaine runway, M1.31.22.51.1-1.10.1-1.21.61.2-0.8
Std. dev. time between licks in bursts0.70.91.90.8-0.81.10.6-0.6-1.01.4
Total sessions with >9 infusions0.60.71.5-0.60.6-1.2-0.40.80.5-1.2
Short access day 1 total inactive lever presses0.10.10.2-0.40.4-0.2-0.40.40.3-0.4
Short access day 10 total inactive lever presses1.01.24.81.1-1.02.2-1.00.10.10.4
Short access day 1 total infusions0.50.51.9-0.40.3-1.4-0.30.70.6-0.8
Short access day 10 total infusions0.60.62.1-0.70.7-1.5-0.10.70.3-0.9
Short access total infusions0.50.61.4-0.20.1-1.2-0.51.00.7-1.0
Short access day 1 locomotion1.51.65.3-1.21.2-2.30.00.70.7-1.4
Short access day 10 total locomotion0.10.10.4-0.20.2-0.60.20.2-0.1-0.3
Short access total locomotion1.31.42.60.7-0.8-1.0-1.01.61.2-1.6
One hour access (0.3 mA shock)0.50.61.5-0.90.9-1.20.6-0.5-0.2-0.3
Compulsive drug intake0.50.51.20.4-0.5-0.1-1.01.11.0-0.4
One hour access (shock baseline)0.60.71.1-1.01.0-1.00.8-0.7-0.5-0.3
Social response proportion1.41.54.02.0-2.01.1-0.70.90.20.2
Social responses1.62.03.51.4-1.41.61.0-1.2-1.41.9
Social time1.11.43.81.9-1.90.8-0.91.00.4-0.0
Soleus weight0.72.14.50.5-0.52.00.8-1.5-1.62.1
Bone: stiffness0.00.00.1-0.20.2-0.4-0.0-0.10.1-0.3
Tibialis anterior weight0.31.03.00.1-0.11.70.2-1.2-0.91.3
Time to tail flick, vehicle, before self-admin0.40.40.50.6-0.60.70.6-0.7-0.70.7
Time to tail flick, vehicle, after self-admin1.92.03.6-1.91.9-1.51.5-1.1-1.10.2
Time to tail flick, test, before self-admin0.40.41.3-1.11.1-0.40.4-0.1-0.40.1
Time to tail flick, test, after self-admin1.81.93.8-1.21.1-0.92.0-1.6-1.60.8
Delta time to tail flick, vehicle, before/after SA1.71.74.5-1.81.8-2.10.5-0.10.2-0.8
Delta time to tail flick, test, before/after SA0.20.10.30.5-0.50.00.4-0.5-0.30.2
Tibia length0.41.11.8-1.41.3-0.8-1.00.70.8-1.3
Ambulatory time before self-admin0.20.30.6-0.20.20.1-0.80.70.7-0.3
Ambulatory time after self-admin0.50.61.50.1-0.00.8-1.11.20.5-0.6
Bone: tissue strength1.91.83.40.9-0.80.3-1.91.71.6-1.5
Total heroin consumption0.40.40.9-0.40.5-0.20.9-1.0-0.80.3
Bone: trabecular number0.30.40.90.2-0.2-0.4-0.61.00.7-0.9
Bone: trabecular spacing0.10.10.6-0.20.2-0.80.10.00.5-0.3
Bone: trabecular thickness1.92.34.9-0.70.70.71.9-1.7-2.21.8
Bone: trabecular tissue density2.33.25.21.2-1.12.21.4-1.9-2.02.3
Water consumed over 24 hours0.40.40.80.9-0.90.9-0.40.70.10.1
Number of responses in last shaping day1.01.12.61.5-1.60.5-1.00.70.8-0.1