Hub : Traits

Cocaine induced anxiety

Post-drug hide time minus pre-drug hide time

Tags: Behavior · Cocaine

Project: p50_paul_meyer_2020

5 loci · 5 genes with independent associations · 6 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr3	127108849	128506156	1	1	5.27e-09	1.77e-02	8.51e-01	Ganc
2	chr6	136337097	137734440	1	1	9.28e-09	2.67e-02	1.05e-06	Kif26a
3	chr7	92127461	93066096	1	1	2.80e-27	3.61e-02	1.00e+00	Ndufb9
4	chr9	83390749	84777604	2	1	0.00e+00	1.98e-01	1.00e+00	Retreg2
5	chr17	61510864	62906219	1	1	6.78e-13	8.13e-02	3.70e-03	Ccny

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	1285.76	3	2	40	0	1.00e+00	Kif26a Ndufb9 Retreg2
BMI without tail	28812.3	4	3	60	-1	4.73e-07	Ccny Kif26a Ndufb9 Retreg2
Body weight	8.89	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Epididymis fat weight	21706.14	4	3	60	-1	1.07e-06	Ccny Kif26a Ndufb9 Retreg2
Glucose	1186.24	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Heart weight	4511.78	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Left kidney weight	28256.38	4	2	40	1	6.34e-06	Ccny Ganc Ndufb9 Retreg2
Right kidney weight	23376.67	4	3	60	1	5.69e-06	Ccny Ganc Ndufb9 Retreg2
Tail length	23038.86	3	2	40	-1	1.30e-04	Ccny Kif26a Retreg2
Length with tail	1539.11	3	2	40	-1	9.70e-04	Kif26a Ndufb9 Retreg2
Length without tail	32337.25	3	2	40	1	2.27e-04	Ccny Ndufb9 Retreg2
Liver weight, left	4845.91	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Liver weight, right	88.25	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Parametrial fat weight	157.8	3	1	20	-1	6.24e-04	Ccny Ganc Retreg2
Retroperitoneal fat weight	5355.25	2	1	20	0	1.00e+00	Ganc Retreg2
Intraocular pressure	13362.94	2	1	20	0	1.00e+00	Ganc Retreg2
Extensor digitorum longus weight	2344.42	2	1	20	0	1.00e+00	Kif26a Retreg2
Soleus weight	40.94	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Tibialis anterior weight	4881.94	1	1	20	0	1.00e+00	Retreg2
Tibia length	1089.18	3	1	20	0	1.00e+00	Ganc Ndufb9 Retreg2
Number of licking bursts	39284.75	3	1	20	-1	4.14e-05	Ccny Ganc Retreg2
Food consumed during 24 hour testing period	35405.76	2	1	20	0	1.00e+00	Ccny Retreg2
Times rat made contact with spout	158.46	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Mean time between licks in bursts	49879.82	3	1	20	-1	2.84e-04	Ccny Ndufb9 Retreg2
Mean num. licks in bursts	47539.71	2	1	20	0	1.00e+00	Ccny Retreg2
Std. dev. time between licks in bursts	47023.26	1	1	20	0	1.00e+00	Retreg2
Water consumed over 24 hours	34477.35	2	1	20	0	1.00e+00	Ccny Retreg2
Patch foraging indifference point 0 sec	115003.89	1	1	20	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	33302.97	3	2	40	1	6.63e-04	Ccny Ndufb9 Retreg2
Indifference point function ln k	35530	3	3	60	-1	4.76e-04	Ccny Ndufb9 Retreg2
Indifference point function log k	35530	3	3	60	-1	4.76e-04	Ccny Ndufb9 Retreg2
Patch foraging total patch changes 0 sec	60133.55	1	1	20	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	3683.47	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Patch foraging total patch changes 18 sec	29447.16	3	1	20	-1	3.52e-04	Ccny Ndufb9 Retreg2
Patch foraging total patch changes 24 sec	41791.78	3	3	60	-1	5.41e-04	Ccny Ndufb9 Retreg2
Patch foraging total patch changes 6 sec	10907.3	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Patch foraging time to switch 0 sec	39163.03	3	2	40	-1	3.05e-04	Kif26a Ndufb9 Retreg2
Patch foraging water rate 0 sec	37209.18	3	2	40	1	2.57e-04	Kif26a Ndufb9 Retreg2
Patch foraging water rate 12 sec	32385.76	4	2	40	1	1.49e-05	Ccny Ganc Kif26a Retreg2
Patch foraging water rate 18 sec	17217.7	5	1	20	1	1.69e-07	Ccny Ganc Kif26a Ndufb9 Retreg2
Patch foraging water rate 24 sec	1182.36	4	2	40	-1	8.96e-04	Ccny Ganc Kif26a Retreg2
Patch foraging water rate 6 sec	821.44	5	3	60	1	2.93e-04	Ccny Ganc Kif26a Ndufb9 Retreg2
Locomotor activity	35.04	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotor testing distance	22396.59	3	2	40	1	1.84e-03	Ccny Ndufb9 Retreg2
Locomotor testing rearing	50814.7	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Light reinforcement 1	51785.62	2	2	40	0	1.00e+00	Ccny Retreg2
Light reinforcement 2	27014.42	3	2	40	1	2.46e-04	Ccny Ndufb9 Retreg2
Reaction time number correct	38379.7	3	3	60	1	2.46e-04	Ccny Ndufb9 Retreg2
Reaction time mean minus median	51458.48	3	1	20	-1	3.84e-04	Ccny Ndufb9 Retreg2
Reaction time mean minus median AUC	69474.35	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Reaction time num false alarms	28557.11	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time num false alarms AUC	35512.89	2	2	40	0	1.00e+00	Ccny Retreg2
Reaction time trials correct on left	38379.7	3	3	60	1	2.46e-04	Ccny Ndufb9 Retreg2
Reaction time trials on left	37513.48	3	3	60	1	2.30e-04	Ccny Ndufb9 Retreg2
Reaction time mean	31467.08	2	1	20	0	1.00e+00	Ccny Retreg2
Reaction time mean AUC	37788.22	2	1	20	0	1.00e+00	Ccny Retreg2
Median of all reaction times	15714.05	1	1	20	0	1.00e+00	Retreg2
Reaction time omissions	11426.44	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Reaction time false alarm rate	448.49	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Reaction time premature initiation rate	18442.81	2	1	20	0	1.00e+00	Ccny Retreg2
Reaction time premature initiations	46245.52	2	1	20	0	1.00e+00	Ccny Retreg2
Std. dev. reaction times	49836.07	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Reaction time trials completed	37513.48	3	3	60	1	2.30e-04	Ccny Ndufb9 Retreg2
Reaction time trials AUC	37939.65	3	2	40	1	2.15e-04	Ccny Ndufb9 Retreg2
Social response proportion	17655.19	2	1	20	0	1.00e+00	Ganc Retreg2
Social responses	1906.34	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Social time	22121.54	2	1	20	0	1.00e+00	Ccny Retreg2
Conditioned locomotion	3044.63	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response after cond. corrected	16463.24	3	1	20	-1	3.66e-04	Ccny Ganc Retreg2
Cocaine response after cond. not corrected	21423.84	2	1	20	0	1.00e+00	Ccny Retreg2
Cocaine response before conditioning	1409.02	2	1	20	0	1.00e+00	Ccny Retreg2
Saline control response	6484.47	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	53410.48	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	45793.79	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active responses	9691.24	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	21056.03	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever presses	7939.8	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. lever reinforcers received	2000.77	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	10912.53	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	24714.14	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. change in total contacts	38264.3	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. index score	23998.4	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. latency score	29242.48	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever contacts	22069.78	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	16773.11	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	52471.02	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	22438.69	2	1	20	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. response bias	5169.79	1	1	20	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	47885.1	3	3	60	-1	2.24e-04	Ccny Ndufb9 Retreg2
Conditioned reinforcement - inactives	38772.86	3	3	60	-1	2.51e-04	Ccny Ndufb9 Retreg2
Conditioned locomotion	10383.93	4	3	60	-1	2.50e-03	Ccny Ganc Ndufb9 Retreg2
Intermittent access intake day 1-15 change	70208.9	2	2	40	0	1.00e+00	Ccny Retreg2
Intermittent access intake escalation	104778.26	1	1	20	0	1.00e+00	Retreg2
Intermittent access intake escalation 2	54050.4	2	2	40	0	1.00e+00	Ccny Retreg2
Intermitt. access day 1 inactive lever presses	47313.02	4	1	20	-1	3.59e-06	Ccny Ganc Ndufb9 Retreg2
Intermitt. access day 15 inactive lever presses	69437.6	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Intermitt. access escalation Index	46255.05	3	1	20	1	2.75e-04	Ccny Ndufb9 Retreg2
Intermittent access day 1 total infusions	51848.67	2	1	20	0	1.00e+00	Ccny Retreg2
Intermittent access day 15 total infusions	43834.25	2	1	20	0	1.00e+00	Ccny Retreg2
Intermittent access terminal intake (last 3 days)	27738.42	3	1	20	0	1.00e+00	Ccny Kif26a Retreg2
Intermittent access total infusions	345.81	2	1	20	0	1.00e+00	Ccny Retreg2
Intermittent access day 1 locomotion	34835.54	2	2	40	0	1.00e+00	Ccny Retreg2
Intermittent access day 15 total locomotion	59302.22	2	2	40	0	1.00e+00	Ccny Retreg2
Intermittent access total locomotion	361.66	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Intermittent access standard deviation	50493.78	3	2	40	-1	2.37e-04	Ccny Kif26a Retreg2
Post-drug Anxiety	4109.05	4	3	60	1	4.50e-05	Ganc Kif26a Ndufb9 Retreg2
Baseline Anxiety	25921.06	3	3	60	-1	4.04e-04	Ccny Ndufb9 Retreg2
Lifetime Intake	3437.35	2	2	40	0	1.00e+00	Ccny Retreg2
Incentive Sensitization - Responses	40908.94	3	3	60	1	3.32e-04	Ccny Ndufb9 Retreg2
Incentive Sensitization - Breakpoint	35710.88	3	3	60	1	2.96e-04	Ccny Ndufb9 Retreg2
Progressive ratio test 1 active lever presses	19991.2	4	2	40	-1	2.04e-05	Ccny Kif26a Ndufb9 Retreg2
Progressive ratio test 1 breakpoint	19265.92	4	2	40	-1	1.85e-05	Ccny Kif26a Ndufb9 Retreg2
Progressive ratio test 1 inactive lever presses	37785.54	3	3	60	-1	2.37e-04	Ccny Ndufb9 Retreg2
Progressive ratio test 2 active lever presses	14320.61	3	2	40	1	2.01e-04	Ccny Ndufb9 Retreg2
Progressive ratio test 2 breakpoint	11682.21	2	2	40	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 inactive lever presses	41034.49	3	2	40	-1	3.74e-04	Ccny Ndufb9 Retreg2
Total sessions with >9 infusions	2683.44	3	2	40	0	1.00e+00	Ccny Kif26a Retreg2
Short access day 1 total inactive lever presses	28609.1	3	3	60	1	9.08e-04	Ccny Ndufb9 Retreg2
Short access day 10 total inactive lever presses	54317.66	3	2	40	-1	7.30e-04	Ccny Ganc Retreg2
Short access day 1 total infusions	37246.47	2	2	40	0	1.00e+00	Ccny Retreg2
Short access day 10 total infusions	15266.76	4	2	40	1	3.14e-05	Ccny Kif26a Ndufb9 Retreg2
Short access total infusions	11353.21	3	2	40	0	1.00e+00	Ccny Ganc Retreg2
Short access day 1 locomotion	21036.9	3	3	60	-1	5.22e-04	Ccny Ndufb9 Retreg2
Short access day 10 total locomotion	45408.08	3	2	40	-1	1.23e-04	Ccny Kif26a Retreg2
Short access total locomotion	17071.49	3	1	20	-1	2.03e-05	Kif26a Ndufb9 Retreg2
Compulsive drug intake	16366.64	3	1	20	1	2.77e-04	Ccny Ndufb9 Retreg2
One hour access (0.3 mA shock)	3241.22	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
One hour access (shock baseline)	46761.01	2	1	20	0	1.00e+00	Ccny Retreg2
Number of responses in last shaping day	17140.86	2	2	40	0	1.00e+00	Ccny Retreg2
Context. condit. distance diff. score	970.59	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 1	7315.11	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Locomotion distance, session 1	2213.01	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 2	9358	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 2	1206.44	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 3	2332.53	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 3	16615.78	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	5866.4	1	1	20	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	12131.92	1	1	20	0	1.00e+00	Retreg2
Locomotion velocity, session 7	1310.17	1	1	20	0	1.00e+00	Retreg2
Locomotion distance, session 7	1879.14	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving bouts, day 7	5257.18	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving duration, day 7	4446.48	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Locomotion velocity, session 8	950.4	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion distance, session 8	339.3	2	1	20	0	1.00e+00	Ganc Retreg2
Degree of sensitization distance	15309.16	1	1	20	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	4256.13	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active minus inactive responses	2066.34	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. active-inactive response ratio	1097.66	1	1	20	0	1.00e+00	Retreg2
Condit. Reinf. active responses	5839.15	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. inactive responses	9694.1	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Incentive salience index mean	7397.37	2	1	20	0	1.00e+00	Ccny Retreg2
Condit. Reinf. lever presses	10719.64	2	1	20	0	1.00e+00	Ganc Retreg2
Time in familiar zone, hab. session 1	20942.04	1	1	20	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	17764.8	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	916.07	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 1	849.35	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 1	571.33	2	1	20	0	1.00e+00	Ccny Retreg2
Time in familiar zone, hab. session 2	11692.92	1	1	20	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	12466.52	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	143.96	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 2	51.92	2	1	20	0	1.00e+00	Ccny Retreg2
Locomotion velocity, hab. session 2	77.91	2	1	20	0	1.00e+00	Ccny Retreg2
Novel to familiar place preference ratio	18508.59	2	1	20	0	1.00e+00	Ccny Retreg2
Novelty place preference	27195.73	2	1	20	0	1.00e+00	Ccny Retreg2
Time in novel zone, NPP test	40844.77	1	1	20	0	1.00e+00	Retreg2
Total zone transitions, NPP test	4127.68	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, NPP test	2379.86	3	2	40	0	1.00e+00	Ccny Ganc Retreg2
Locomotion velocity, NPP test	1356.55	3	2	40	0	1.00e+00	Ccny Ganc Retreg2
Pavlov. Cond. lever latency	1100.78	2	1	20	0	1.00e+00	Ganc Retreg2
Pavlov. Cond. magazine entry latency	8.77	2	0	0	0	1.00e+00	Ccny Ganc
Pavlov. Cond. change in total contacts	1518.77	3	1	20	0	1.00e+00	Ccny Ganc Retreg2
Pavlov. Cond. index score	887.64	2	1	20	0	1.00e+00	Ganc Retreg2
Pavlov. Cond. latency score	924.09	2	1	20	0	1.00e+00	Ganc Retreg2
Pavlov. Cond. lever contacts	1016.1	3	1	20	0	1.00e+00	Ganc Ndufb9 Retreg2
Pavlov. Cond. magazine entry number	726.9	3	1	20	0	1.00e+00	Ccny Ganc Retreg2
Pavlov. Cond. intertrial magazine entries	139.41	4	1	20	-0.95	4.54e-02	Ganc Kif26a Ndufb9 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	1940.27	1	1	20	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	1307.47	2	1	20	0	1.00e+00	Ganc Retreg2
Bone: apparent density	11138.75	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone surface	25125.6	1	1	20	0	1.00e+00	Retreg2
Bone volume	33831.7	1	1	20	0	1.00e+00	Retreg2
Bone: connectivity density	3557.17	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical apparent density	15092.86	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Bone: cortical area	9468.26	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	923.93	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	2407.81	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical thickness	817.52	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical thickness	4070.39	3	1	20	0	1.00e+00	Ganc Ndufb9 Retreg2
Bone: cortical tissue density	16155.62	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Bone: elastic displacement	14817.48	1	1	20	0	1.00e+00	Retreg2
Bone: elastic work	1494.59	1	1	20	0	1.00e+00	Retreg2
Bone: endosteal estimation	17631.97	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: endosteal perimeter	22350.62	1	1	20	0	1.00e+00	Retreg2
Bone: final force	7031.22	1	1	20	0	1.00e+00	Retreg2
Bone: final moment	1042.62	1	1	20	0	1.00e+00	Retreg2
Bone: marrow area	18537.3	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum diameter	12203.48	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum force	34553.99	1	1	20	0	1.00e+00	Retreg2
Bone: maximum moment	24715.64	1	1	20	0	1.00e+00	Retreg2
Bone: minimum diameter	17196.64	1	1	20	0	1.00e+00	Retreg2
Bone: periosteal estimation	38190.5	1	1	20	0	1.00e+00	Retreg2
Bone: periosteal perimeter	43183.28	1	1	20	0	1.00e+00	Retreg2
Bone: post-yield work	50847.58	1	1	20	0	1.00e+00	Retreg2
Bone: stiffness	35564.91	1	1	20	0	1.00e+00	Retreg2
Bone: tissue strength	12264.67	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular number	20584.56	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular spacing	15655.12	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular thickness	33264.33	1	1	20	0	1.00e+00	Retreg2
Bone: trabecular tissue density	17885.93	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Breakpoint value in progressive ratio session	28115.21	3	1	20	-1	2.10e-04	Ccny Ganc Retreg2
Distance traveled before self-admin	33523.66	3	2	40	-1	6.44e-05	Ccny Ndufb9 Retreg2
Distance traveled after self-admin	50469.31	2	2	40	0	1.00e+00	Ccny Retreg2
Delta time in closed arm before/after self-admin	689.79	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Delta time in open arm before/after self-admin	18299.4	2	2	40	0	1.00e+00	Ccny Retreg2
Diff in mean of infusions in LGA sessions	36169.04	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Extinction: sum of active levers before priming	22946.4	3	3	60	-1	5.56e-04	Ccny Ndufb9 Retreg2
Active lever presses in extinction session 6	1673.08	2	2	40	0	1.00e+00	Ccny Retreg2
Delta distance traveled before/after self-admin	3156.2	3	3	60	0.99	5.45e-03	Ccny Ndufb9 Retreg2
Delta ambulatory time before/after self-admin	24032.85	3	2	40	1	5.10e-05	Ccny Ndufb9 Retreg2
Time in closed arm before self-admin	22073.81	3	2	40	1	1.46e-04	Ccny Ganc Retreg2
Time in closed arm after self-admin	9901.19	2	2	40	0	1.00e+00	Ccny Retreg2
Time in open arm before self-admin	6961.91	4	3	60	0.99	5.12e-04	Ccny Kif26a Ndufb9 Retreg2
Time in open arm after self-admin	669.46	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Sum of active levers in priming session hrs 5-6	1945.79	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Time to tail flick, vehicle, before self-admin	12969.21	3	2	40	-1	2.58e-03	Ccny Ndufb9 Retreg2
Time to tail flick, vehicle, after self-admin	23671.55	4	2	40	-1	3.30e-05	Ccny Ganc Ndufb9 Retreg2
Time to tail flick, test, before self-admin	10954.71	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Time to tail flick, test, after self-admin	2022.59	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Delta time to tail flick, vehicle, before/after SA	12304.44	2	2	40	0	1.00e+00	Ccny Retreg2
Delta time to tail flick, test, before/after SA	18952.76	3	1	20	0	1.00e+00	Ccny Ndufb9 Retreg2
Ambulatory time before self-admin	57053.67	2	2	40	0	1.00e+00	Ccny Retreg2
Ambulatory time after self-admin	44153.3	2	2	40	0	1.00e+00	Ccny Retreg2
Total heroin consumption	547.18	2	2	40	0	1.00e+00	Ccny Retreg2
Area under the delay curve	27210.77	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 0s delay	4741.82	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 16s delay	24960.39	2	2	40	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 2s delay	416.46	2	1	20	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 24s delay	33351.69	2	2	40	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 4s delay	870.6	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Delay disc. indifference point, 8s delay	50718.73	1	1	20	0	1.00e+00	Retreg2
Delay discount exponential model param	20076.53	2	1	20	0	1.00e+00	Ccny Retreg2
Delay discount hyperbolic model param	22862.57	1	1	20	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	50060.01	2	1	20	0	1.00e+00	Ccny Retreg2
Change in fecal boli incidents, locomotor task	7889.79	3	3	60	0	1.00e+00	Ccny Ndufb9 Retreg2
Time >=10cm from walls, locomotor time 1	12331.74	3	2	40	1	1.07e-03	Ccny Ndufb9 Retreg2
Bouts of movement, locomotor time 1	13897.62	3	2	40	0	1.00e+00	Ccny Kif26a Retreg2
Total resting periods, locomotor time 1	3960.44	3	2	40	0	1.00e+00	Ccny Kif26a Retreg2
Rest time, locomotor task time 1	18996.61	3	1	20	-1	1.35e-05	Ccny Ndufb9 Retreg2
Distance moved, locomotor task time 1	39837.96	3	3	60	1	3.64e-06	Ccny Ndufb9 Retreg2
Vertical activity count, locomotor time 1	73027.33	2	1	20	0	1.00e+00	Ganc Retreg2
Time >=10cm from walls, locomotor time 2	53999.89	2	1	20	0	1.00e+00	Ccny Retreg2
Bouts of movement, locomotor time 2	43586.52	3	2	40	-1	3.06e-04	Ccny Ganc Retreg2
Total resting periods, locomotor time 2	47530.24	3	2	40	-1	2.66e-04	Ccny Ganc Retreg2
Rest time, locomotor task time 2	20954.13	3	2	40	1	9.36e-04	Ccny Ndufb9 Retreg2
Distance moved, locomotor task time 2	17217.33	2	2	40	0	1.00e+00	Ccny Retreg2
Vertical activity count, locomotor time 2	46160.97	2	2	40	0	1.00e+00	Ccny Retreg2
Weight adjusted by age	40522.05	3	3	60	-1	7.46e-05	Ccny Ndufb9 Retreg2
Seeking ratio, delayed vs. immediate footshock	24709.08	2	2	40	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber	4103.43	4	3	60	1	1.75e-03	Ccny Kif26a Ndufb9 Retreg2
Locomotion in novel chamber post-restriction	38665.63	3	1	20	1	9.80e-05	Ccny Ndufb9 Retreg2
Progressive ratio	39495.34	3	3	60	1	4.91e-05	Ccny Ndufb9 Retreg2
Food seeking constrained by brief footshock	3673.46	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, punishment vs. effort	29579.13	3	3	60	-1	3.40e-05	Ccny Ndufb9 Retreg2
Run reversals in cocaine runway, females	18598.36	2	1	20	0	1.00e+00	Ccny Retreg2
Run reversals in cocaine runway, males	7496.92	3	2	40	-1	9.49e-04	Ccny Ndufb9 Retreg2
Latency to leave start box in cocaine runway	29317.55	2	2	40	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway, F	14201.52	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Latency to leave start box in cocaine runway, M	2456.15	3	2	40	0	1.00e+00	Ccny Ndufb9 Retreg2
Co content in liver	4721.74	1	1	20	0	1.00e+00	Retreg2
Cu content in liver	89.33	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Fe content in liver	5656.2	1	1	20	0	1.00e+00	Retreg2
K content in liver	6593.53	1	1	20	0	1.00e+00	Retreg2
Mg content in liver	24493.99	1	1	20	0	1.00e+00	Retreg2
Mn content in liver	2219.37	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Na content in liver	8325.4	2	1	20	0	1.00e+00	Ndufb9 Retreg2
Rb content in liver	241.33	2	2	40	0	1.00e+00	Ndufb9 Retreg2
Se content in liver	8.64	1	0	0	0	1.00e+00	Ndufb9
Zn content in liver	7891.81	2	2	40	0	1.00e+00	Ndufb9 Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.07
Adipose	alternative TSS	0	0	1.05
Adipose	gene expression	0	0	1.03
Adipose	isoform ratio	0	0	1.06
Adipose	intron excision ratio	0	0	1.08
Adipose	mRNA stability	1	0	1.09
BLA	alternative polyA	0	0	1.01
BLA	alternative TSS	0	0	1.05
BLA	gene expression	0	0	1.04
BLA	isoform ratio	0	0	1.03
BLA	intron excision ratio	0	0	1.01
BLA	mRNA stability	0	0	1.04
Brain	alternative polyA	0	0	1.01
Brain	alternative TSS	0	0	1.07
Brain	gene expression	0	0	1.05
Brain	isoform ratio	0	0	1.04
Brain	intron excision ratio	0	0	1.02
Brain	mRNA stability	0	0	1.04
Eye	alternative polyA	0	0	0.98
Eye	alternative TSS	0	0	1
Eye	gene expression	0	0	0.98
Eye	isoform ratio	0	0	1.19
Eye	intron excision ratio	0	0	1.06
Eye	mRNA stability	0	0	1.09
IC	alternative polyA	0	0	1.03
IC	alternative TSS	0	0	1.07
IC	gene expression	0	0	1.07
IC	isoform ratio	0	0	1.07
IC	intron excision ratio	1	0	1.05
IC	mRNA stability	0	0	1.07
IL	alternative polyA	0	0	0.93
IL	alternative TSS	0	0	1.03
IL	gene expression	0	0	1.04
IL	isoform ratio	0	0	1.02
IL	intron excision ratio	0	0	0.79
IL	mRNA stability	0	0	1.02
LHb	alternative polyA	0	0	1.06
LHb	alternative TSS	0	0	1.02
LHb	gene expression	0	0	1.02
LHb	isoform ratio	0	0	1.11
LHb	intron excision ratio	0	0	0.96
LHb	mRNA stability	0	0	1.05
Liver	alternative polyA	0	0	1.09
Liver	alternative TSS	0	0	1.03
Liver	gene expression	0	0	1.06
Liver	isoform ratio	0	0	1.05
Liver	intron excision ratio	0	0	1.06
Liver	mRNA stability	0	0	1.08
NAcc	alternative polyA	2	0.1	123.56
NAcc	alternative TSS	0	0	1.08
NAcc	gene expression	0	0	1.04
NAcc	isoform ratio	0	0	1.07
NAcc	intron excision ratio	0	0	1.02
NAcc	mRNA stability	0	0	1.09
OFC	alternative polyA	0	0	1
OFC	alternative TSS	0	0	1.02
OFC	gene expression	0	0	1.02
OFC	isoform ratio	0	0	1.03
OFC	intron excision ratio	0	0	0.93
OFC	mRNA stability	0	0	1.03
PL	alternative polyA	0	0	1.04
PL	alternative TSS	0	0	1.07
PL	gene expression	0	0	1.03
PL	isoform ratio	0	0	1.04
PL	intron excision ratio	0	0	1.04
PL	mRNA stability	0	0	1.07
pVTA	alternative polyA	0	0	1
pVTA	alternative TSS	0	0	1.06
pVTA	gene expression	1	0	1.07
pVTA	isoform ratio	0	0	1.08
pVTA	intron excision ratio	1	0	1.06
pVTA	mRNA stability	0	0	1.09
RMTg	alternative polyA	0	0	0.9
RMTg	alternative TSS	0	0	1.09
RMTg	gene expression	0	0	1.05
RMTg	isoform ratio	0	0	1.03
RMTg	intron excision ratio	0	0	1.02
RMTg	mRNA stability	0	0	1.09