Hub : Genes

Arhgef17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA intron excision ratio chr1_164664222_164668333 0.14 0.08 3.2e-05 0.09 0.09 0.09 0.09 1.7e-05 1.4e-05 1.4e-05 1.1e-05
2 BLA intron excision ratio chr1_164664222_164698646 0.15 0.09 2.9e-05 0.09 0.09 0.09 0.05 2.4e-05 1.2e-05 2.3e-05 8.2e-04
3 PL mRNA stability Arhgef17 0.03 0.02 2.8e-03 0.02 0.02 0.02 0.02 1.1e-03 1.1e-03 4.6e-03 1.9e-03
4 Adipose mRNA stability Arhgef17 0.09 0.05 7.0e-08 0.04 0.05 0.04 0.04 6.3e-05 4.3e-06 8.2e-06 1.3e-05
5 NAcc intron excision ratio chr1_164664222_164698646 0.05 0.03 9.3e-06 0.04 0.04 0.04 0.04 6.8e-07 1.9e-06 9.1e-07 1.1e-06
6 NAcc intron excision ratio chr1_164664222_164668333 0.04 0.03 5.8e-04 0.03 0.02 0.02 0.02 1.0e-04 3.3e-04 8.3e-04 2.5e-04
7 Brain gene expression Arhgef17 0.2 0.09 0.0e+00 0.18 0.19 0.18 0.19 7.8e-17 9.8e-18 5.4e-17 3.9e-17

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.30.61.00.6-0.80.10.91.0-1.0-0.8
Area under the delay curve0.10.10.50.7-0.10.4-0.0-0.20.20.3
BMI with tail0.72.45.00.20.50.8-1.4-2.12.22.0
BMI without tail0.84.57.9-1.31.50.3-2.4-2.82.82.3
Body weight1.46.210.4-1.41.61.1-2.7-3.23.23.2
Weight adjusted by age0.20.50.9-0.40.50.1-0.9-0.91.00.8
Bone surface0.30.61.3-1.21.0-0.9-0.8-0.50.50.0
Bone volume0.10.20.6-0.80.7-0.6-0.5-0.30.20.0
Breakpoint value in progressive ratio session0.71.32.10.5-1.30.61.41.4-1.4-0.8
Number of licking bursts0.92.98.02.1-2.32.81.10.0-0.11.0
Context. condit. distance diff. score1.31.64.3-1.71.6-2.1-0.60.3-0.3-1.0
Locomotion velocity, session 11.01.11.50.8-1.0-0.21.21.2-1.2-1.2
Locomotion distance, session 10.50.61.9-0.80.6-1.4-0.00.5-0.5-1.0
Locomotion velocity, session 20.10.10.3-0.50.3-0.2-0.4-0.30.30.1
Locomotion distance, session 20.20.30.8-0.70.7-0.9-0.30.1-0.1-0.4
Locomotion velocity, session 30.60.61.4-0.90.5-1.20.10.7-0.7-1.0
Locomotion distance, session 30.91.12.6-0.70.5-1.60.31.0-1.0-1.5
Stereotopy head waving bouts, day 30.40.41.1-0.1-0.11.0-0.4-0.60.61.0
Stereotopy head waving duration, day 30.10.10.2-0.50.3-0.4-0.10.2-0.2-0.3
Locomotion velocity, session 70.40.40.60.6-0.70.20.80.7-0.7-0.6
Locomotion distance, session 70.10.20.50.7-0.40.50.30.1-0.10.2
Stereotopy head waving bouts, day 71.82.15.4-2.31.6-2.2-0.80.2-0.2-1.1
Stereotopy head waving duration, day 71.82.35.7-2.41.8-2.2-1.1-0.30.3-0.7
Locomotion velocity, session 80.60.72.2-1.51.0-1.1-0.6-0.00.0-0.4
Locomotion distance, session 81.42.04.5-2.11.9-2.1-1.0-0.10.1-0.6
Degree of sensitization distance1.92.04.80.10.21.6-1.1-1.61.62.2
Degree of sensitization stereotypy3.23.58.7-2.82.3-2.9-1.20.0-0.0-1.2
Conditioned locomotion0.20.30.70.2-0.10.10.60.8-0.9-0.3
Cocaine response after cond. corrected0.71.13.11.3-1.21.80.3-0.40.41.0
Cocaine response after cond. not corrected0.20.41.01.0-0.80.70.4-0.10.10.2
Cocaine response before conditioning1.11.44.7-0.80.8-2.20.10.7-0.7-1.6
Saline control response1.62.34.8-2.22.0-1.1-1.7-1.11.10.6
Bone: connectivity density0.50.81.60.6-0.8-0.50.91.0-1.0-1.3
Bone: cortical apparent density0.81.34.01.4-1.32.00.6-0.00.00.9
Bone: cortical area0.40.60.9-0.90.80.1-0.9-0.90.90.8
Bone: cortical porosity0.60.71.4-0.10.4-1.20.40.9-0.9-1.1
Bone: cortical porosity0.60.71.7-0.40.5-1.30.30.8-0.8-1.2
Bone: cortical thickness0.20.40.60.7-0.80.70.70.5-0.5-0.2
Bone: cortical thickness0.00.10.2-0.30.4-0.3-0.10.1-0.1-0.1
Bone: cortical tissue density0.81.33.81.5-1.41.90.80.1-0.10.8
Condit. Reinf. active minus inactive responses0.60.71.0-0.80.80.1-1.0-1.01.00.9
Condit. Reinf. active-inactive response ratio1.11.21.7-0.91.1-0.2-1.3-1.31.31.0
Condit. Reinf. active responses0.20.30.5-0.50.40.3-0.6-0.50.50.7
Condit. Reinf. inactive responses0.10.10.10.1-0.20.20.30.4-0.4-0.1
Incentive salience index mean0.50.70.9-0.80.8-0.0-1.0-0.90.90.8
Condit. Reinf. lever presses0.10.20.4-0.70.5-0.4-0.5-0.40.40.2
Condit. Reinf. active minus inactive responses5.17.813.9-3.73.6-2.4-3.2-2.32.31.1
Condit. Reinf. active-inactive response ratio0.81.22.3-1.51.4-1.2-1.2-0.80.80.1
Condit. Reinf. active responses8.412.120.4-4.54.5-2.6-4.0-3.03.01.6
Condit. Reinf. inactive responses4.77.011.6-3.33.4-1.7-3.1-2.42.41.6
Condit. Reinf. lever presses11.917.231.8-5.65.6-4.4-4.5-2.92.90.9
Condit. Reinf. lever reinforcers received9.413.223.2-4.84.7-3.0-4.2-3.03.01.5
Conditioned reinforcement - actives0.20.83.2-0.31.0-1.8-0.10.3-0.2-1.0
Conditioned reinforcement - inactives0.10.31.01.0-0.40.30.50.5-0.4-0.1
Conditioned locomotion1.32.06.2-0.51.0-2.50.31.2-1.1-2.0
Patch foraging indifference point 0 sec0.92.65.9-1.92.4-2.4-1.5-0.80.7-0.3
Patch foraging indifference point AUC0.41.01.8-0.70.60.5-1.1-1.31.31.3
Delay disc. indifference point, 0s delay0.91.02.0-1.41.4-0.8-1.2-0.70.70.4
Delay disc. indifference point, 16s delay0.10.20.60.8-0.30.30.40.3-0.3-0.1
Delay disc. indifference point, 2s delay1.01.11.8-1.11.1-0.3-1.3-1.11.10.9
Delay disc. indifference point, 24s delay0.61.02.61.6-1.11.21.00.6-0.60.0
Delay disc. indifference point, 4s delay2.12.23.2-1.71.5-0.2-1.8-1.61.61.4
Delay disc. indifference point, 8s delay0.10.10.90.9-0.20.10.1-0.00.00.1
Indifference point function ln k0.51.53.5-0.40.5-1.90.71.2-1.2-1.8
Indifference point function log k0.51.53.5-0.40.5-1.90.71.2-1.2-1.8
Patch foraging total patch changes 0 sec0.82.34.8-1.72.2-2.1-1.5-0.90.8-0.1
Patch foraging total patch changes 12 sec1.72.33.2-1.31.6-0.2-1.8-1.81.71.4
Patch foraging total patch changes 18 sec0.92.23.8-1.41.9-1.4-1.7-1.51.50.6
Patch foraging total patch changes 24 sec0.62.13.1-1.21.6-0.4-1.8-1.71.71.4
Patch foraging total patch changes 6 sec0.20.40.9-0.71.0-0.8-0.7-0.40.40.0
Patch foraging time to switch 0 sec0.93.56.72.5-2.62.02.11.2-1.3-0.4
Patch foraging water rate 0 sec0.62.45.1-2.02.3-2.2-1.5-0.70.7-0.2
Patch foraging water rate 12 sec0.31.34.4-1.11.5-2.1-0.60.1-0.1-0.8
Patch foraging water rate 18 sec0.71.53.2-1.81.6-1.2-1.5-0.80.80.3
Patch foraging water rate 24 sec0.81.12.9-0.40.7-1.70.31.1-1.1-1.4
Patch foraging water rate 6 sec0.50.72.4-0.81.0-1.6-0.40.4-0.4-0.7
Seeking ratio, delayed vs. immediate footshock1.11.62.71.4-1.60.61.51.2-1.1-0.9
Distance traveled before self-admin0.20.51.50.5-1.01.20.60.2-0.00.3
Distance traveled after self-admin1.01.82.90.6-1.1-0.11.61.7-1.7-1.6
Extensor digitorum longus weight0.41.63.00.4-0.11.2-0.9-1.71.71.7
Bone: elastic displacement2.12.64.51.7-2.11.01.91.6-1.6-1.1
Bone: elastic work2.73.55.72.2-2.40.92.21.8-1.8-1.4
Bone: endosteal estimation1.74.16.0-1.92.1-0.7-2.4-2.42.41.7
Bone: endosteal perimeter1.94.66.7-2.42.4-1.0-2.6-2.42.31.6
Epididymis fat weight0.10.71.91.4-1.01.30.4-0.20.20.6
Delta time in closed arm before/after self-admin1.81.73.61.4-0.81.9-0.3-1.21.21.7
Delta time in open arm before/after self-admin1.61.93.8-1.82.0-1.5-1.6-0.80.90.2
Diff in mean of infusions in LGA sessions1.32.35.51.0-2.22.41.51.2-1.20.2
Delay discount exponential model param0.10.10.5-0.70.2-0.40.10.2-0.2-0.4
Extinction: sum of active levers before priming0.10.10.2-0.50.30.0-0.4-0.40.30.3
Active lever presses in extinction session 62.92.95.9-0.60.4-2.11.12.1-2.0-2.4
Bone: final force0.00.10.20.3-0.10.50.20.2-0.10.2
Bone: final moment0.00.00.10.10.10.3-0.00.00.00.3
Food consumed during 24 hour testing period1.22.36.5-2.11.8-2.5-0.9-0.00.0-1.1
Glucose0.00.00.1-0.1-0.30.10.0-0.20.1-0.1
Heart weight0.40.61.4-1.11.1-1.2-0.6-0.20.2-0.3
Delay discount hyperbolic model param0.10.20.3-0.5-0.0-0.40.30.5-0.5-0.6
Intermittent access intake day 1-15 change0.10.31.2-0.50.4-1.1-0.10.3-0.1-0.8
Intermittent access intake escalation0.10.51.7-0.80.5-1.3-0.10.3-0.2-0.9
Intermittent access intake escalation 20.10.20.8-0.30.7-0.9-0.5-0.20.2-0.2
Intermitt. access day 1 inactive lever presses0.10.82.01.3-1.01.40.50.0-0.00.6
Intermitt. access day 15 inactive lever presses0.21.01.61.0-1.00.41.31.1-1.2-0.9
Intermitt. access escalation Index0.00.00.0-0.10.1-0.1-0.2-0.10.10.1
Intermittent access day 1 total infusions0.41.13.0-1.41.4-1.7-0.60.0-0.1-0.6
Intermittent access day 15 total infusions0.51.13.5-1.21.3-1.9-0.40.3-0.2-1.0
Intermittent access terminal intake (last 3 days)0.71.33.5-1.41.6-1.9-0.80.00.0-0.7
Intermittent access total infusions1.11.33.0-1.41.7-1.7-1.0-0.30.4-0.3
Intermittent access day 1 locomotion0.20.30.8-0.20.3-0.90.20.5-0.5-0.9
Intermittent access day 15 total locomotion0.31.02.9-0.60.5-1.70.40.8-0.7-1.6
Intermittent access total locomotion0.50.61.9-0.90.9-1.4-0.20.3-0.3-0.9
Intermittent access standard deviation0.10.51.0-0.60.50.2-0.7-1.00.90.8
Left kidney weight0.32.74.6-0.81.10.5-1.8-2.12.12.0
Right kidney weight0.64.57.8-0.91.60.5-2.4-2.82.82.6
Cocaine induced anxiety0.61.73.41.8-1.81.51.50.8-0.8-0.2
Post-drug Anxiety1.01.13.01.1-1.51.71.00.5-0.50.3
Baseline Anxiety0.40.72.3-1.51.0-0.3-1.0-0.50.50.5
Tail length1.79.112.9-3.32.50.5-3.6-3.43.43.2
Length with tail1.66.99.7-3.12.30.5-3.1-2.82.82.9
Length without tail0.00.20.4-0.60.00.7-0.3-0.20.20.6
Times rat made contact with spout0.50.51.1-0.2-0.21.0-0.5-0.80.81.0
Lifetime Intake1.31.63.9-1.61.8-2.0-1.1-0.30.3-0.4
Liver weight, left0.81.42.70.30.20.9-1.0-1.61.61.7
Liver weight, right1.52.55.80.6-0.22.0-1.0-1.81.82.4
Locomotor activity0.20.30.7-0.70.8-0.8-0.4-0.0-0.1-0.2
Locomotor testing distance0.82.13.9-2.01.9-1.1-1.6-1.11.10.6
Locomotor testing rearing0.51.92.7-1.61.4-0.0-1.6-1.51.51.4
Locomotion in novel chamber0.70.91.61.2-0.0-1.20.80.8-0.9-1.2
Locomotion in novel chamber post-restriction0.41.24.3-1.21.2-2.1-0.50.1-0.1-1.1
Fecal boli incidents, locomotor time 10.30.81.60.90.1-1.30.60.8-0.8-1.1
Change in fecal boli incidents, locomotor task0.30.30.90.7-0.60.90.1-0.10.10.4
Time >=10cm from walls, locomotor time 10.60.82.9-0.41.2-1.7-0.30.2-0.2-0.8
Bouts of movement, locomotor time 10.10.10.2-0.30.5-0.4-0.2-0.00.0-0.1
Total resting periods, locomotor time 10.20.30.50.20.1-0.60.40.6-0.6-0.7
Rest time, locomotor task time 10.50.71.10.8-0.4-0.40.91.1-1.1-1.1
Distance moved, locomotor task time 10.41.01.7-0.80.40.5-1.0-1.31.31.2
Vertical activity count, locomotor time 10.10.91.3-1.00.80.0-1.1-1.11.11.0
Time >=10cm from walls, locomotor time 20.51.43.6-1.21.9-1.1-1.4-0.90.90.6
Bouts of movement, locomotor time 20.41.42.5-0.41.10.3-1.4-1.41.41.6
Total resting periods, locomotor time 20.20.92.0-0.10.70.5-1.0-1.21.21.4
Rest time, locomotor task time 21.22.03.91.7-2.01.61.61.0-1.0-0.2
Distance moved, locomotor task time 22.12.74.8-2.22.2-1.4-1.9-1.31.30.6
Vertical activity count, locomotor time 20.61.42.2-1.31.5-0.6-1.4-1.21.20.9
Light reinforcement 10.52.55.12.3-2.22.01.40.6-0.70.2
Light reinforcement 20.30.71.10.6-1.00.01.00.9-1.0-1.0
Bone: marrow area1.53.75.5-1.71.9-0.5-2.3-2.32.31.7
Bone: maximum diameter1.63.35.1-2.22.1-0.9-2.1-1.91.81.2
Bone: maximum force0.00.00.00.2-0.10.20.10.1-0.10.1
Bone: maximum moment0.00.00.0-0.10.10.0-0.1-0.00.10.1
Mean time between licks in bursts1.37.911.6-2.93.3-0.9-3.4-3.03.02.5
Mean num. licks in bursts1.02.66.1-2.22.2-2.5-1.2-0.20.3-0.7
Cd content in liver0.40.40.8-0.1-0.20.9-0.4-0.70.70.9
Co content in liver1.61.92.9-1.61.7-0.6-1.7-1.41.41.1
Cu content in liver1.92.33.9-1.01.20.2-1.7-2.02.01.7
Fe content in liver0.00.00.00.0-0.10.10.10.1-0.1-0.0
K content in liver0.30.30.7-0.10.10.7-0.4-0.70.70.8
Mg content in liver0.10.10.2-0.40.4-0.3-0.3-0.30.30.1
Mn content in liver1.92.13.11.5-1.60.41.81.6-1.6-1.3
Na content in liver0.50.51.9-1.40.7-0.9-0.5-0.20.2-0.3
Rb content in liver0.30.30.8-0.90.6-0.6-0.5-0.30.3-0.0
Se content in liver3.64.37.82.6-2.81.82.41.7-1.7-0.9
Sr content in liver0.30.30.7-0.0-0.1-0.70.40.6-0.6-0.9
Zn content in liver2.22.64.2-1.72.1-1.3-1.9-1.61.60.8
Bone: minimum diameter2.13.96.1-1.61.50.6-2.2-2.52.42.3
Time in familiar zone, hab. session 10.20.20.4-0.40.20.3-0.5-0.60.60.6
Time in novel zone, hab. session 10.20.20.60.8-0.60.60.40.2-0.20.1
Total zone transitions, hab. session 10.40.61.2-0.5-0.3-0.50.61.0-1.0-1.1
Total locomotion distance, hab. session 11.11.63.70.2-0.11.7-0.8-1.41.41.9
Locomotion velocity, hab. session 10.71.02.5-0.00.01.3-0.7-1.11.11.6
Time in familiar zone, hab. session 21.31.42.9-1.31.7-1.1-1.4-1.01.00.6
Time in novel zone, hab. session 20.70.71.20.9-1.10.41.00.9-0.9-0.7
Total zone transitions, hab. session 21.11.43.8-1.91.1-1.7-0.30.6-0.6-1.1
Total locomotion distance, hab. session 21.52.03.7-1.11.00.9-1.5-1.61.61.9
Locomotion velocity, hab. session 21.82.34.6-1.10.91.1-1.6-1.71.72.1
Novel to familiar place preference ratio0.10.10.5-0.70.6-0.0-0.30.1-0.10.3
Novelty place preference0.10.20.6-0.80.6-0.0-0.30.1-0.10.3
Time in novel zone, NPP test0.20.30.9-0.90.8-0.2-0.40.1-0.10.2
Total zone transitions, NPP test0.30.41.0-0.50.0-0.80.40.7-0.7-1.0
Total locomotion distance, NPP test0.81.12.60.2-0.01.3-0.7-1.21.21.6
Locomotion velocity, NPP test0.81.12.50.5-0.41.6-0.5-1.11.11.6
Intraocular pressure0.50.81.90.8-0.6-0.90.90.8-0.8-1.4
Delta distance traveled before/after self-admin1.21.33.5-1.11.0-1.90.00.7-0.8-1.4
Delta ambulatory time before/after self-admin0.81.43.6-1.10.9-1.90.20.8-1.0-1.5
Parametrial fat weight0.40.82.11.3-1.51.20.6-0.10.10.3
Pavlov. Cond. lever latency0.91.22.21.5-1.51.21.20.8-0.8-0.2
Pavlov. Cond. magazine entry latency2.43.15.6-2.32.4-1.9-1.9-1.21.20.4
Pavlov. Cond. change in total contacts1.11.22.2-1.41.5-1.2-1.2-0.70.70.2
Pavlov. Cond. index score2.02.64.5-2.12.1-1.7-1.8-1.21.20.3
Pavlov. Cond. latency score1.92.44.4-2.12.1-1.7-1.7-1.11.10.3
Pavlov. Cond. lever contacts0.91.11.9-1.31.4-1.1-1.2-0.90.90.3
Pavlov. Cond. magazine entry number2.43.05.62.3-2.41.91.91.2-1.2-0.3
Pavlov. Cond. intertrial magazine entries0.60.71.20.7-1.10.91.00.8-0.8-0.3
Pavlov. Cond. lever-magazine prob. diff.1.72.13.8-1.91.9-1.6-1.6-1.11.10.2
Pavlov. Cond. response bias1.11.42.5-1.61.6-1.3-1.3-0.90.90.2
Pavlov. Cond. lever latency11.916.731.75.6-5.64.84.32.5-2.5-0.4
Pavlov. Cond. magazine entry latency2.02.86.5-2.32.3-2.5-1.4-0.40.4-0.6
Pavlov. Cond. change in total contacts5.413.229.0-5.44.9-4.2-3.7-2.02.00.1
Pavlov. Cond. index score7.712.123.5-4.84.8-4.2-3.6-2.02.00.2
Pavlov. Cond. latency score6.410.319.9-4.54.4-4.0-3.2-1.81.80.0
Pavlov. Cond. lever contacts11.116.331.4-5.65.5-4.6-4.3-2.52.50.5
Pavlov. Cond. magazine entry number4.05.110.93.3-3.13.31.90.7-0.70.7
Pavlov. Cond. intertrial magazine entries0.71.62.7-0.80.70.7-1.4-1.61.61.6
Pavlov. Cond. lever-magazine prob. diff.7.511.522.2-4.74.7-3.9-3.6-2.12.10.3
Pavlov. Cond. response bias11.616.031.3-5.65.5-4.8-4.1-2.32.30.2
Time in closed arm before self-admin1.01.83.7-1.81.1-1.90.11.0-1.0-1.5
Time in closed arm after self-admin0.80.91.70.6-1.10.51.31.0-1.1-0.7
Time in open arm before self-admin2.53.08.73.0-2.42.11.40.3-0.30.3
Time in open arm after self-admin0.50.61.20.20.40.2-0.9-1.01.10.9
Bone: periosteal estimation1.33.04.4-1.61.8-0.5-2.1-2.12.01.5
Bone: periosteal perimeter1.42.84.0-1.81.8-0.6-2.0-1.91.81.3
Bone: post-yield work0.00.10.1-0.20.3-0.1-0.3-0.30.30.2
Progressive ratio test 1 active lever presses0.20.30.80.1-0.2-0.50.50.7-0.7-0.9
Progressive ratio test 1 breakpoint0.20.30.70.1-0.2-0.40.50.6-0.6-0.8
Progressive ratio test 1 inactive lever presses0.10.30.50.6-0.2-0.40.60.6-0.7-0.7
Progressive ratio test 2 active lever presses0.30.40.7-0.80.8-0.8-0.6-0.40.4-0.0
Progressive ratio test 2 breakpoint0.30.40.8-0.90.8-0.8-0.7-0.40.4-0.1
Progressive ratio test 2 inactive lever presses0.10.30.9-0.30.4-0.90.20.5-0.4-0.8
Incentive Sensitization - Responses0.30.81.5-1.21.2-0.8-1.1-0.70.70.4
Incentive Sensitization - Breakpoint0.30.71.4-1.21.1-0.8-0.9-0.60.60.2
Sum of active levers in priming session hrs 5-60.20.20.5-0.2-0.1-0.00.40.7-0.7-0.5
Progressive ratio0.10.41.0-0.70.3-1.00.10.4-0.4-0.9
Food seeking constrained by brief footshock1.41.72.9-1.11.6-0.5-1.7-1.41.41.1
Seeking ratio, punishment vs. effort1.02.23.5-0.81.20.4-1.8-1.91.81.8
Retroperitoneal fat weight1.56.516.51.5-1.64.1-0.8-2.42.43.5
Reaction time number correct0.41.32.80.1-0.2-0.81.01.7-1.7-1.4
Reaction time mean minus median0.10.91.6-1.01.3-0.6-1.2-1.00.90.7
Reaction time mean minus median AUC0.10.71.8-1.01.3-1.1-0.8-0.40.40.0
Reaction time num false alarms0.91.54.31.7-1.32.10.5-0.20.21.1
Reaction time num false alarms AUC0.40.92.41.5-1.01.40.6-0.00.00.6
Reaction time trials correct on left0.41.32.80.1-0.2-0.81.01.7-1.7-1.4
Reaction time trials on left0.41.42.90.1-0.2-0.81.01.7-1.7-1.4
Reaction time mean0.30.62.10.8-0.51.4-0.0-0.30.31.1
Reaction time mean AUC0.30.62.10.9-0.81.50.30.1-0.10.8
Median of all reaction times0.61.03.01.3-1.01.70.50.1-0.10.9
Reaction time omissions0.20.30.70.10.00.6-0.4-0.60.60.8
Reaction time false alarm rate0.91.33.21.5-1.01.80.2-0.80.71.3
Reaction time premature initiation rate2.64.06.3-1.51.9-0.2-2.5-2.42.52.1
Reaction time premature initiations0.51.62.6-1.21.6-0.7-1.6-1.21.30.9
Std. dev. reaction times0.51.63.0-0.61.00.5-1.5-1.61.51.7
Reaction time trials completed0.41.42.90.1-0.2-0.81.01.7-1.7-1.4
Reaction time trials AUC0.30.92.10.1-0.1-0.60.81.5-1.4-1.1
Run reversals in cocaine runway, females2.62.96.0-0.60.41.6-1.7-2.12.02.5
Run reversals in cocaine runway, males0.10.10.30.1-0.50.00.50.2-0.5-0.4
Latency to leave start box in cocaine runway1.21.75.41.4-1.62.30.4-0.30.51.2
Latency to leave start box in cocaine runway, F1.62.06.30.8-1.22.5-0.2-1.01.11.9
Latency to leave start box in cocaine runway, M0.60.61.41.2-0.90.30.80.7-0.6-0.5
Std. dev. time between licks in bursts2.24.16.1-1.41.90.2-2.4-2.52.52.3
Total sessions with >9 infusions1.62.04.0-1.82.0-2.0-1.4-0.70.7-0.2
Short access day 1 total inactive lever presses0.00.10.2-0.20.4-0.3-0.3-0.0-0.00.0
Short access day 10 total inactive lever presses0.10.82.61.6-1.00.80.90.6-0.5-0.1
Short access day 1 total infusions1.83.56.9-2.52.6-2.0-2.1-1.21.20.5
Short access day 10 total infusions1.01.63.1-1.71.8-1.6-1.3-0.70.6-0.1
Short access total infusions1.42.04.5-1.72.0-2.1-1.3-0.50.4-0.4
Short access day 1 locomotion0.91.65.2-1.51.3-2.3-0.40.2-0.2-1.2
Short access day 10 total locomotion0.31.23.2-1.81.4-1.2-1.0-0.60.6-0.0
Short access total locomotion0.30.51.5-0.70.5-1.20.00.3-0.3-1.0
One hour access (0.3 mA shock)0.60.72.2-0.81.2-1.5-0.7-0.20.2-0.4
Compulsive drug intake1.92.84.41.2-1.70.12.12.0-1.9-1.7
One hour access (shock baseline)0.71.84.0-1.72.0-1.8-1.4-0.70.70.0
Social response proportion0.40.51.10.8-0.21.0-0.2-0.60.51.0
Social responses1.01.33.40.10.31.3-0.9-1.31.31.8
Social time1.42.13.71.5-1.91.51.81.3-1.3-0.5
Soleus weight1.33.77.70.30.31.8-1.6-2.52.52.8
Bone: stiffness0.20.51.60.5-0.41.30.0-0.40.41.0
Tibialis anterior weight0.31.11.8-0.50.70.4-1.1-1.31.31.4
Time to tail flick, vehicle, before self-admin0.20.20.5-0.70.5-0.6-0.3-0.0-0.4-0.4
Time to tail flick, vehicle, after self-admin0.50.92.5-1.11.3-1.6-0.7-0.60.6-0.5
Time to tail flick, test, before self-admin1.21.32.1-1.31.2-0.2-1.5-1.31.31.0
Time to tail flick, test, after self-admin1.31.42.2-0.81.20.2-1.5-1.31.31.5
Delta time to tail flick, vehicle, before/after SA0.30.31.0-0.20.7-1.0-0.3-0.40.7-0.3
Delta time to tail flick, test, before/after SA0.30.41.31.1-0.60.60.60.4-0.40.1
Tibia length0.92.46.7-1.91.8-2.6-0.40.8-0.8-1.4
Ambulatory time before self-admin0.20.71.40.8-1.21.01.00.6-0.5-0.2
Ambulatory time after self-admin1.42.24.1-0.1-0.6-0.81.61.9-2.0-2.0
Bone: tissue strength2.22.33.81.0-1.3-0.31.71.9-1.9-1.8
Total heroin consumption0.20.20.6-0.80.2-0.20.10.6-0.5-0.3
Bone: trabecular number1.01.83.01.2-1.70.71.61.4-1.4-1.0
Bone: trabecular spacing0.40.61.6-0.91.0-1.3-0.5-0.10.1-0.4
Bone: trabecular thickness0.20.31.30.2-0.51.10.20.0-0.00.6
Bone: trabecular tissue density1.01.85.60.6-0.62.4-0.3-1.01.02.0
Water consumed over 24 hours0.20.30.60.4-0.80.50.60.5-0.5-0.3
Number of responses in last shaping day0.50.61.30.7-0.21.0-0.4-0.90.81.1