Best TWAS P = 2.18e-08 · Best GWAS P= 5.53e-08 conditioned to 3.47e-02
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | LOC120097342 | gene expression | LOC120097342 | 0.15 | 1402 | 0.03 | 1.5e-04 | -5.21 | 1.89e-07 | 0.6 | FALSE |
| Adipose | Tenm4 | gene expression | Tenm4 | 0.08 | 64 | 0.01 | 3.4e-02 | 5.6 | 2.18e-08 | 0.7 | TRUE |
| Liver | Prcp | gene expression | Prcp | 0.62 | 79 | 0.35 | 1.0e-40 | -5.27 | 1.38e-07 | 0.66 | FALSE |
| NAcc | Tenm4 | gene expression | Tenm4 | 0.04 | 1 | 0.02 | 2.8e-04 | -5.37 | 7.81e-08 | 0.84 | FALSE |
| NAcc | Tenm4 | intron excision ratio | chr1_160112209_160192294 | 0.34 | 5 | 0.04 | 2.4e-07 | 5.29 | 1.22e-07 | 0.92 | FALSE |
| PL | Rab30 | intron excision ratio | chr1_156216273_156289040 | 0.05 | 1770 | 0.01 | 9.4e-03 | -5.25 | 1.50e-07 | 0.52 | FALSE |