ShA PR total presses

Total sum of active lever presses during pr 01

Tags: Behavior · Cocaine

Project: u01_olivier_george_cocaine

3 loci · 3 genes with independent associations · 4 total associated genes

Significant Loci

# Chr Start pos End pos # assoc genes # joint models Best TWAS P Best GWAS P Cond GWAS P Joint genes
1 chr2 144511896 145970994 2 1 4.75e-09 1.14e-01 1.00e+00 Mindy4b
2 chr9 83390749 84777604 1 1 0.00e+00 6.63e-01 1.00e+00 Retreg2
3 chr13 84702566 86100919 1 1 4.53e-10 1.82e-01 1.16e-38 Olfml2b

Pleiotropic Associations

Trait Chi2 ratio # genes+ # genes++ % genes++ Corr Corr P Genes
BMI with tail 221.68 4 2 66.7 -0.98 2.11e-02 Clrn1 Mindy4b Olfml2b Retreg2
BMI without tail 14314.59 4 1 33.3 1 1.70e-03 Clrn1 Mindy4b Olfml2b Retreg2
Body weight 4.71 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Epididymis fat weight 36276.19 1 1 33.3 0 1.00e+00 Retreg2
Glucose 541.77 1 1 33.3 0 1.00e+00 Retreg2
Heart weight 3065.65 1 1 33.3 0 1.00e+00 Retreg2
Left kidney weight 18350.51 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Right kidney weight 40399.64 1 1 33.3 0 1.00e+00 Retreg2
Tail length 28919.24 1 1 33.3 0 1.00e+00 Retreg2
Length with tail 1484.46 1 1 33.3 0 1.00e+00 Retreg2
Length without tail 23619.04 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Liver weight, left 3487.23 1 1 33.3 0 1.00e+00 Retreg2
Liver weight, right 25.94 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Parametrial fat weight 181.56 1 1 33.3 0 1.00e+00 Retreg2
Retroperitoneal fat weight 1314.33 3 1 33.3 0 1.00e+00 Clrn1 Mindy4b Retreg2
Intraocular pressure 10386.52 1 1 33.3 0 1.00e+00 Retreg2
Extensor digitorum longus weight 360.71 3 1 33.3 0 1.00e+00 Clrn1 Mindy4b Retreg2
Soleus weight 13.4 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Tibialis anterior weight 580.53 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Tibia length 767.35 1 1 33.3 0 1.00e+00 Retreg2
Number of licking bursts 67424.86 1 1 33.3 0 1.00e+00 Retreg2
Food consumed during 24 hour testing period 17757.05 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Times rat made contact with spout 71.66 1 1 33.3 0 1.00e+00 Retreg2
Mean time between licks in bursts 111630.35 1 1 33.3 0 1.00e+00 Retreg2
Mean num. licks in bursts 56750.08 1 1 33.3 0 1.00e+00 Retreg2
Std. dev. time between licks in bursts 29750.31 1 1 33.3 0 1.00e+00 Retreg2
Water consumed over 24 hours 17088.38 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Patch foraging indifference point 0 sec 39171.5 1 1 33.3 0 1.00e+00 Retreg2
Patch foraging indifference point AUC 25067.09 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Indifference point function ln k 18554.99 3 1 33.3 0 1.00e+00 Clrn1 Olfml2b Retreg2
Indifference point function log k 18554.99 3 1 33.3 0 1.00e+00 Clrn1 Olfml2b Retreg2
Patch foraging total patch changes 0 sec 41947.04 1 1 33.3 0 1.00e+00 Retreg2
Patch foraging total patch changes 12 sec 2302.98 1 1 33.3 0 1.00e+00 Retreg2
Patch foraging total patch changes 18 sec 20229.52 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Patch foraging total patch changes 24 sec 37402.76 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Patch foraging total patch changes 6 sec 3896.58 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Patch foraging time to switch 0 sec 33248.73 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Patch foraging water rate 0 sec 30215.74 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Patch foraging water rate 12 sec 70639.93 1 1 33.3 0 1.00e+00 Retreg2
Patch foraging water rate 18 sec 16866.36 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Patch foraging water rate 24 sec 519.06 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Patch foraging water rate 6 sec 837.86 1 1 33.3 0 1.00e+00 Retreg2
Locomotor testing distance 27661.69 1 1 33.3 0 1.00e+00 Retreg2
Locomotor testing rearing 31700.47 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Light reinforcement 1 33158.6 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Light reinforcement 2 12249.62 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Reaction time number correct 31740.61 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Reaction time mean minus median 39987.38 3 1 33.3 0 1.00e+00 Clrn1 Olfml2b Retreg2
Reaction time mean minus median AUC 41332.3 3 1 33.3 0 1.00e+00 Clrn1 Olfml2b Retreg2
Reaction time num false alarms 15357.42 1 1 33.3 0 1.00e+00 Retreg2
Reaction time num false alarms AUC 35016.83 1 1 33.3 0 1.00e+00 Retreg2
Reaction time trials correct on left 31740.61 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Reaction time trials on left 30446.63 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Reaction time mean 9923.55 3 3 100 0 1.00e+00 Clrn1 Mindy4b Retreg2
Reaction time mean AUC 12937.33 3 3 100 0 1.00e+00 Clrn1 Mindy4b Retreg2
Median of all reaction times 2649.55 3 2 66.7 0 1.00e+00 Clrn1 Mindy4b Retreg2
Reaction time omissions 2795.35 3 1 33.3 0 1.00e+00 Clrn1 Mindy4b Retreg2
Reaction time false alarm rate 107.66 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Reaction time premature initiation rate 4871.37 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Reaction time premature initiations 26874.85 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Std. dev. reaction times 15222.73 4 1 33.3 1 1.46e-03 Clrn1 Mindy4b Olfml2b Retreg2
Reaction time trials completed 30446.63 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Reaction time trials AUC 31069.96 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Social response proportion 4394.41 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Social responses 1265.33 1 1 33.3 0 1.00e+00 Retreg2
Social time 11650.06 1 1 33.3 0 1.00e+00 Retreg2
Conditioned locomotion 1400.08 1 1 33.3 0 1.00e+00 Retreg2
Cocaine response after cond. corrected 19128.47 1 1 33.3 0 1.00e+00 Retreg2
Cocaine response after cond. not corrected 9288.6 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Cocaine response before conditioning 655.41 1 1 33.3 0 1.00e+00 Retreg2
Saline control response 3160.68 1 1 33.3 0 1.00e+00 Retreg2
Condit. Reinf. active minus inactive responses 14521.56 1 1 33.3 0 1.00e+00 Retreg2
Condit. Reinf. active-inactive response ratio 9576.56 3 1 33.3 0 1.00e+00 Clrn1 Mindy4b Retreg2
Condit. Reinf. active responses 2302.04 1 1 33.3 0 1.00e+00 Retreg2
Condit. Reinf. inactive responses 3633.31 3 1 33.3 0 1.00e+00 Clrn1 Mindy4b Retreg2
Condit. Reinf. lever presses 3863.86 1 1 33.3 0 1.00e+00 Retreg2
Condit. Reinf. lever reinforcers received 469.54 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. lever latency 2531.81 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. magazine entry latency 13282.18 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. change in total contacts 39811.91 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. index score 12744.53 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. latency score 16150.81 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. lever contacts 5331.08 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. magazine entry number 4012.39 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. intertrial magazine entries 34989.79 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. lever-magazine prob. diff. 11800.43 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. response bias 1164.95 1 1 33.3 0 1.00e+00 Retreg2
Conditioned reinforcement - actives 33602.34 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Conditioned reinforcement - inactives 32436.1 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Conditioned locomotion 3459.04 3 2 66.7 0 1.00e+00 Mindy4b Olfml2b Retreg2
Intermittent access intake day 1-15 change 42631.28 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Intermittent access intake escalation 42029.35 3 2 66.7 0 1.00e+00 Mindy4b Olfml2b Retreg2
Intermittent access intake escalation 2 12063.98 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Intermitt. access day 1 inactive lever presses 90307.7 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Intermitt. access day 15 inactive lever presses 61812.2 2 2 66.7 0 1.00e+00 Olfml2b Retreg2
Intermitt. access escalation Index 23334.24 4 1 33.3 -1 9.44e-04 Clrn1 Mindy4b Olfml2b Retreg2
Intermittent access day 1 total infusions 22046.33 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Intermittent access day 15 total infusions 16251.91 3 2 66.7 0 1.00e+00 Clrn1 Olfml2b Retreg2
Intermittent access terminal intake (last 3 days) 12413.3 2 2 66.7 0 1.00e+00 Olfml2b Retreg2
Intermittent access total infusions 69.26 3 1 33.3 0 1.00e+00 Clrn1 Olfml2b Retreg2
Intermittent access day 1 locomotion 11667.38 3 2 66.7 0 1.00e+00 Mindy4b Olfml2b Retreg2
Intermittent access day 15 total locomotion 42776.71 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Intermittent access total locomotion 46.89 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Intermittent access standard deviation 56985.83 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Cocaine induced anxiety 69097.7 1 1 33.3 0 1.00e+00 Retreg2
Post-drug Anxiety 4753.56 1 1 33.3 0 1.00e+00 Retreg2
Baseline Anxiety 16756.18 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Lifetime Intake 557.51 3 1 33.3 0 1.00e+00 Clrn1 Olfml2b Retreg2
Incentive Sensitization - Responses 23792.61 3 2 66.7 0 1.00e+00 Mindy4b Olfml2b Retreg2
Incentive Sensitization - Breakpoint 18436.1 3 2 66.7 0 1.00e+00 Mindy4b Olfml2b Retreg2
Progressive ratio test 1 active lever presses 10665.25 3 1 33.3 0 1.00e+00 Clrn1 Olfml2b Retreg2
Progressive ratio test 1 breakpoint 10102.65 3 1 33.3 0 1.00e+00 Clrn1 Olfml2b Retreg2
Progressive ratio test 1 inactive lever presses 62205.59 1 1 33.3 0 1.00e+00 Retreg2
Progressive ratio test 2 active lever presses 5093.71 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Progressive ratio test 2 breakpoint 2854.51 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Progressive ratio test 2 inactive lever presses 72504.33 1 1 33.3 0 1.00e+00 Retreg2
Total sessions with >9 infusions 498.92 4 1 33.3 -0.99 5.05e-03 Clrn1 Mindy4b Olfml2b Retreg2
Short access day 1 total inactive lever presses 13145.23 3 2 66.7 0 1.00e+00 Clrn1 Mindy4b Retreg2
Short access day 10 total inactive lever presses 46285.97 3 1 33.3 0 1.00e+00 Clrn1 Olfml2b Retreg2
Short access day 1 total infusions 19198.69 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Short access day 10 total infusions 5682.07 4 1 33.3 -1 2.47e-03 Clrn1 Mindy4b Olfml2b Retreg2
Short access total infusions 2932.69 3 1 33.3 0 1.00e+00 Clrn1 Mindy4b Retreg2
Short access day 1 locomotion 12404.35 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Short access day 10 total locomotion 29411.21 3 3 100 0 1.00e+00 Mindy4b Olfml2b Retreg2
Short access total locomotion 6237.05 3 2 66.7 0 1.00e+00 Mindy4b Olfml2b Retreg2
Compulsive drug intake 9343.13 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
One hour access (0.3 mA shock) 1171.76 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
One hour access (shock baseline) 27496.88 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Number of responses in last shaping day 4547.26 3 1 33.3 0 1.00e+00 Clrn1 Mindy4b Retreg2
Context. condit. distance diff. score 212.47 1 1 33.3 0 1.00e+00 Retreg2
Locomotion velocity, session 1 3523.61 1 1 33.3 0 1.00e+00 Retreg2
Locomotion distance, session 1 1024.77 1 1 33.3 0 1.00e+00 Retreg2
Locomotion velocity, session 2 1082.02 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Locomotion distance, session 2 256.34 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Locomotion velocity, session 3 507.49 1 1 33.3 0 1.00e+00 Retreg2
Locomotion distance, session 3 4009.46 1 1 33.3 0 1.00e+00 Retreg2
Stereotopy head waving bouts, day 3 1361.96 1 1 33.3 0 1.00e+00 Retreg2
Stereotopy head waving duration, day 3 2872.44 1 1 33.3 0 1.00e+00 Retreg2
Locomotion velocity, session 7 292.79 1 1 33.3 0 1.00e+00 Retreg2
Locomotion distance, session 7 856.72 1 1 33.3 0 1.00e+00 Retreg2
Stereotopy head waving bouts, day 7 2509.72 1 1 33.3 0 1.00e+00 Retreg2
Stereotopy head waving duration, day 7 2115.93 1 1 33.3 0 1.00e+00 Retreg2
Locomotion velocity, session 8 207.27 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Locomotion distance, session 8 147.88 1 1 33.3 0 1.00e+00 Retreg2
Degree of sensitization distance 3670.85 1 1 33.3 0 1.00e+00 Retreg2
Degree of sensitization stereotypy 2042.98 1 1 33.3 0 1.00e+00 Retreg2
Condit. Reinf. active minus inactive responses 484.11 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Condit. Reinf. active-inactive response ratio 126.1 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Condit. Reinf. active responses 1386.69 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Condit. Reinf. inactive responses 4681.39 1 1 33.3 0 1.00e+00 Retreg2
Incentive salience index mean 3540.72 1 1 33.3 0 1.00e+00 Retreg2
Condit. Reinf. lever presses 5282.33 1 1 33.3 0 1.00e+00 Retreg2
Time in familiar zone, hab. session 1 11168.49 1 1 33.3 0 1.00e+00 Retreg2
Time in novel zone, hab. session 1 9232.79 1 1 33.3 0 1.00e+00 Retreg2
Total zone transitions, hab. session 1 429.72 1 1 33.3 0 1.00e+00 Retreg2
Total locomotion distance, hab. session 1 394.1 1 1 33.3 0 1.00e+00 Retreg2
Locomotion velocity, hab. session 1 266.96 1 1 33.3 0 1.00e+00 Retreg2
Time in familiar zone, hab. session 2 5880.03 1 1 33.3 0 1.00e+00 Retreg2
Time in novel zone, hab. session 2 6311.49 1 1 33.3 0 1.00e+00 Retreg2
Total zone transitions, hab. session 2 34.9 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Total locomotion distance, hab. session 2 22.17 1 1 33.3 0 1.00e+00 Retreg2
Locomotion velocity, hab. session 2 31.27 1 1 33.3 0 1.00e+00 Retreg2
Novel to familiar place preference ratio 15339.58 1 1 33.3 0 1.00e+00 Retreg2
Novelty place preference 14927.56 1 1 33.3 0 1.00e+00 Retreg2
Time in novel zone, NPP test 10685.62 1 1 33.3 0 1.00e+00 Retreg2
Total zone transitions, NPP test 1935.62 1 1 33.3 0 1.00e+00 Retreg2
Total locomotion distance, NPP test 1687.31 1 1 33.3 0 1.00e+00 Retreg2
Locomotion velocity, NPP test 953.07 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. lever latency 491.79 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. change in total contacts 1037.76 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. index score 384.43 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. latency score 404.63 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. lever contacts 677.08 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. magazine entry number 248.34 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Pavlov. Cond. intertrial magazine entries 66.78 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Pavlov. Cond. lever-magazine prob. diff. 418.89 1 1 33.3 0 1.00e+00 Retreg2
Pavlov. Cond. response bias 583.93 1 1 33.3 0 1.00e+00 Retreg2
Bone: apparent density 5461.77 1 1 33.3 0 1.00e+00 Retreg2
Bone surface 6197.68 1 1 33.3 0 1.00e+00 Retreg2
Bone volume 8624.75 1 1 33.3 0 1.00e+00 Retreg2
Bone: connectivity density 1667.52 1 1 33.3 0 1.00e+00 Retreg2
Bone: cortical apparent density 12020.36 1 1 33.3 0 1.00e+00 Retreg2
Bone: cortical area 4581.96 1 1 33.3 0 1.00e+00 Retreg2
Bone: cortical porosity 432.96 1 1 33.3 0 1.00e+00 Retreg2
Bone: cortical porosity 1113.18 1 1 33.3 0 1.00e+00 Retreg2
Bone: cortical thickness 189.28 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Bone: cortical thickness 1462.17 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Bone: cortical tissue density 13002.58 1 1 33.3 0 1.00e+00 Retreg2
Bone: elastic displacement 3805.08 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Bone: elastic work 184.45 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Bone: endosteal estimation 2973.27 3 1 33.3 0 1.00e+00 Clrn1 Mindy4b Retreg2
Bone: endosteal perimeter 11863.6 1 1 33.3 0 1.00e+00 Retreg2
Bone: final force 1600.36 1 1 33.3 0 1.00e+00 Retreg2
Bone: final moment 219.15 1 1 33.3 0 1.00e+00 Retreg2
Bone: marrow area 4716.83 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Bone: maximum diameter 6068.73 1 1 33.3 0 1.00e+00 Retreg2
Bone: maximum force 8697.09 1 1 33.3 0 1.00e+00 Retreg2
Bone: maximum moment 5989.29 1 1 33.3 0 1.00e+00 Retreg2
Bone: minimum diameter 4100.86 1 1 33.3 0 1.00e+00 Retreg2
Bone: periosteal estimation 9791.57 1 1 33.3 0 1.00e+00 Retreg2
Bone: periosteal perimeter 11400.25 1 1 33.3 0 1.00e+00 Retreg2
Bone: post-yield work 6839.22 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Bone: stiffness 9032.86 1 1 33.3 0 1.00e+00 Retreg2
Bone: tissue strength 2995.95 1 1 33.3 0 1.00e+00 Retreg2
Bone: trabecular number 10739.78 1 1 33.3 0 1.00e+00 Retreg2
Bone: trabecular spacing 7952.12 1 1 33.3 0 1.00e+00 Retreg2
Bone: trabecular thickness 8476.26 1 1 33.3 0 1.00e+00 Retreg2
Bone: trabecular tissue density 7279.6 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
LgA early post infusion interval 26676.79 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
LgA late post infusion interval 17465.64 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
LgA early loading 36387.93 3 2 66.7 0 1.00e+00 Clrn1 Mindy4b Retreg2
LgA late loading 46422.47 3 2 66.7 0 1.00e+00 Clrn1 Mindy4b Retreg2
LgA early average infusions 14611.86 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
LgA late average infusions 31536.61 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
LgA early timeout 6034.29 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
LgA late timeout 29420.17 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
LgA early titration 62424.33 1 1 33.3 0 1.00e+00 Retreg2
LgA late titration 33828.08 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
LgA total infusion 13531.08 3 1 33.3 0 1.00e+00 Clrn1 Mindy4b Retreg2
LgA PC1 addiction-like behavior 35045.21 3 2 66.7 0 1.00e+00 Clrn1 Mindy4b Retreg2
LgA PR total presses 2193.31 3 2 66.7 0 1.00e+00 Clrn1 Mindy4b Retreg2
ShA early post infusion interval 4043.28 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
ShA late post infusion interval 300.19 1 1 33.3 0 1.00e+00 Retreg2
ShA early loading 71.58 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
ShA late loading 18922.11 3 1 33.3 0 1.00e+00 Clrn1 Mindy4b Retreg2
ShA early average infusions 9718.61 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
ShA late average infusions 2975.33 3 2 66.7 0 1.00e+00 Clrn1 Mindy4b Retreg2
ShA early timeout 263.96 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
ShA late timeout 6152.69 3 1 33.3 0 1.00e+00 Clrn1 Olfml2b Retreg2
ShA early titration 723.43 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
ShA late titration 3833.91 3 2 66.7 0 1.00e+00 Clrn1 Mindy4b Retreg2
ShA total infusions 9330.19 4 2 66.7 1 3.26e-04 Clrn1 Mindy4b Olfml2b Retreg2
Shock compulsivity 117768.67 1 1 33.3 0 1.00e+00 Retreg2
Total infusions 7195.64 4 1 33.3 1 3.31e-04 Clrn1 Mindy4b Olfml2b Retreg2
Breakpoint value in progressive ratio session 37605.61 1 1 33.3 0 1.00e+00 Retreg2
Distance traveled before self-admin 25270.44 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Distance traveled after self-admin 32464.08 1 1 33.3 0 1.00e+00 Retreg2
Delta time in closed arm before/after self-admin 244.69 1 1 33.3 0 1.00e+00 Retreg2
Delta time in open arm before/after self-admin 7570.02 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Diff in mean of infusions in LGA sessions 18332.6 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Extinction: sum of active levers before priming 14190.48 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Active lever presses in extinction session 6 738.98 1 1 33.3 0 1.00e+00 Retreg2
Delta distance traveled before/after self-admin 2940.47 1 1 33.3 0 1.00e+00 Retreg2
Delta ambulatory time before/after self-admin 30849.75 1 1 33.3 0 1.00e+00 Retreg2
Time in closed arm before self-admin 26866.11 1 1 33.3 0 1.00e+00 Retreg2
Time in closed arm after self-admin 4591.18 1 1 33.3 0 1.00e+00 Retreg2
Time in open arm before self-admin 2920.76 3 1 33.3 0 1.00e+00 Clrn1 Mindy4b Retreg2
Time in open arm after self-admin 477.73 1 1 33.3 0 1.00e+00 Retreg2
Sum of active levers in priming session hrs 5-6 498.46 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Time to tail flick, vehicle, before self-admin 6685.94 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Time to tail flick, vehicle, after self-admin 21076.82 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Time to tail flick, test, before self-admin 8139.55 1 1 33.3 0 1.00e+00 Retreg2
Time to tail flick, test, after self-admin 716.84 2 2 66.7 0 1.00e+00 Mindy4b Retreg2
Delta time to tail flick, vehicle, before/after SA 4908.61 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Delta time to tail flick, test, before/after SA 7855.87 2 2 66.7 0 1.00e+00 Mindy4b Retreg2
Ambulatory time before self-admin 78874.38 1 1 33.3 0 1.00e+00 Retreg2
Ambulatory time after self-admin 13310.23 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Total heroin consumption 87.34 3 1 33.3 0 1.00e+00 Clrn1 Olfml2b Retreg2
Area under the delay curve 6206.1 4 1 33.3 -1 3.72e-03 Clrn1 Mindy4b Olfml2b Retreg2
Delay disc. indifference point, 0s delay 727.48 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Delay disc. indifference point, 16s delay 5495.91 4 1 33.3 -1 3.74e-03 Clrn1 Mindy4b Olfml2b Retreg2
Delay disc. indifference point, 2s delay 57.53 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Delay disc. indifference point, 24s delay 16225.81 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Delay disc. indifference point, 4s delay 217.22 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Delay disc. indifference point, 8s delay 33362.4 1 1 33.3 0 1.00e+00 Retreg2
Delay discount exponential model param 4238.64 4 1 33.3 1 4.11e-03 Clrn1 Mindy4b Olfml2b Retreg2
Delay discount hyperbolic model param 3079.13 4 1 33.3 0.99 5.18e-03 Clrn1 Mindy4b Olfml2b Retreg2
Fecal boli incidents, locomotor time 1 30608.31 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Change in fecal boli incidents, locomotor task 2842.13 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Time >=10cm from walls, locomotor time 1 4347.89 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Bouts of movement, locomotor time 1 10785.17 1 1 33.3 0 1.00e+00 Retreg2
Total resting periods, locomotor time 1 2793.59 1 1 33.3 0 1.00e+00 Retreg2
Rest time, locomotor task time 1 22349.64 1 1 33.3 0 1.00e+00 Retreg2
Distance moved, locomotor task time 1 68821.85 1 1 33.3 0 1.00e+00 Retreg2
Vertical activity count, locomotor time 1 142354.07 1 1 33.3 0 1.00e+00 Retreg2
Time >=10cm from walls, locomotor time 2 23733.1 3 2 66.7 0 1.00e+00 Mindy4b Olfml2b Retreg2
Bouts of movement, locomotor time 2 27349.8 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Total resting periods, locomotor time 2 33018.84 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Rest time, locomotor task time 2 12755.16 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Distance moved, locomotor task time 2 4245.69 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Vertical activity count, locomotor time 2 26790.07 2 2 66.7 0 1.00e+00 Mindy4b Retreg2
Weight adjusted by age 35393.44 2 1 33.3 0 1.00e+00 Clrn1 Retreg2
Seeking ratio, delayed vs. immediate footshock 6730.03 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Locomotion in novel chamber 1308.25 3 1 33.3 0 1.00e+00 Clrn1 Olfml2b Retreg2
Locomotion in novel chamber post-restriction 32714.2 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Progressive ratio 33946.59 2 1 33.3 0 1.00e+00 Mindy4b Retreg2
Food seeking constrained by brief footshock 1875.34 1 1 33.3 0 1.00e+00 Retreg2
Seeking ratio, punishment vs. effort 41283.25 1 1 33.3 0 1.00e+00 Retreg2
Run reversals in cocaine runway, females 4711.19 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Run reversals in cocaine runway, males 7664.74 1 1 33.3 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway 8151.76 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Latency to leave start box in cocaine runway, F 2395.19 3 1 33.3 0 1.00e+00 Mindy4b Olfml2b Retreg2
Latency to leave start box in cocaine runway, M 1716.51 1 1 33.3 0 1.00e+00 Retreg2
Co content in liver 1133.25 1 1 33.3 0 1.00e+00 Retreg2
Cu content in liver 39.92 1 1 33.3 0 1.00e+00 Retreg2
Fe content in liver 1344.53 1 1 33.3 0 1.00e+00 Retreg2
K content in liver 1519.62 1 1 33.3 0 1.00e+00 Retreg2
Mg content in liver 3022.31 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Mn content in liver 511.02 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Na content in liver 2013.06 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Rb content in liver 47.17 2 1 33.3 0 1.00e+00 Olfml2b Retreg2
Se content in liver 7.65 1 0 0 0 1.00e+00 Olfml2b
Sr content in liver 7.22 1 0 0 0 1.00e+00 Olfml2b
Zn content in liver 3745.55 1 1 33.3 0 1.00e+00 Retreg2

Associations by panel

Tissue RNA modality # hits % hits/tests Avg chisq
Adipose alternative polyA 0 0 1.07
Adipose alternative TSS 0 0 1.01
Adipose gene expression 0 0 1.04
Adipose isoform ratio 0 0 1.05
Adipose intron excision ratio 0 0 1.02
Adipose mRNA stability 0 0 1.05
BLA alternative polyA 0 0 1.13
BLA alternative TSS 0 0 1
BLA gene expression 1 0 1.05
BLA isoform ratio 0 0 1.04
BLA intron excision ratio 0 0 0.99
BLA mRNA stability 0 0 1.07
Brain alternative polyA 0 0 1.12
Brain alternative TSS 0 0 1.05
Brain gene expression 0 0 1.06
Brain isoform ratio 0 0 1.08
Brain intron excision ratio 0 0 1.06
Brain mRNA stability 0 0 1.05
Eye alternative polyA 0 0 1.02
Eye alternative TSS 0 0 1.03
Eye gene expression 0 0 1.01
Eye isoform ratio 0 0 1.02
Eye intron excision ratio 0 0 0.91
Eye mRNA stability 0 0 1.05
IC alternative polyA 0 0 1.22
IC alternative TSS 0 0 1.06
IC gene expression 0 0 1.07
IC isoform ratio 0 0 1.09
IC intron excision ratio 0 0 1.02
IC mRNA stability 0 0 1.1
IL alternative polyA 0 0 1.07
IL alternative TSS 0 0 1.03
IL gene expression 0 0 1.06
IL isoform ratio 0 0 1.07
IL intron excision ratio 0 0 1.08
IL mRNA stability 0 0 1.09
LHb alternative polyA 0 0 1.21
LHb alternative TSS 0 0 1.02
LHb gene expression 0 0 1.05
LHb isoform ratio 0 0 1.14
LHb intron excision ratio 0 0 1.08
LHb mRNA stability 0 0 1.06
Liver alternative polyA 0 0 1.07
Liver alternative TSS 0 0 0.99
Liver gene expression 0 0 1.04
Liver isoform ratio 0 0 0.98
Liver intron excision ratio 0 0 0.99
Liver mRNA stability 0 0 1
NAcc alternative polyA 1 0 8.48
NAcc alternative TSS 0 0 1.05
NAcc gene expression 0 0 1.06
NAcc isoform ratio 0 0 1.11
NAcc intron excision ratio 1 0 1.07
NAcc mRNA stability 0 0 1.04
OFC alternative polyA 0 0 1.15
OFC alternative TSS 0 0 0.98
OFC gene expression 0 0 1.05
OFC isoform ratio 0 0 1.09
OFC intron excision ratio 0 0 1.05
OFC mRNA stability 0 0 1.06
PL alternative polyA 0 0 1.11
PL alternative TSS 0 0 1.11
PL gene expression 1 0 1.07
PL isoform ratio 0 0 1.07
PL intron excision ratio 0 0 1.05
PL mRNA stability 0 0 1.05
pVTA alternative polyA 0 0 1.15
pVTA alternative TSS 0 0 1.04
pVTA gene expression 0 0 1.06
pVTA isoform ratio 0 0 1.11
pVTA intron excision ratio 0 0 1.06
pVTA mRNA stability 0 0 1.06
RMTg alternative polyA 0 0 1.08
RMTg alternative TSS 0 0 1.09
RMTg gene expression 0 0 1.07
RMTg isoform ratio 0 0 1.02
RMTg intron excision ratio 0 0 0.99
RMTg mRNA stability 0 0 1.16