Hub : Traits

Shock compulsivity

The total sum of infusions in shock 03 session after the first shock (inclusive of the first shock infusion)

Tags: Behavior · Cocaine

Project: u01_olivier_george_cocaine

4 loci · 4 genes with independent associations · 5 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr3	89562573	90958818	1	1	1.59e-09	2.29e-01	1.00e+00	Serping1
2	chr9	83390749	84777604	2	1	0.00e+00	6.37e-01	1.00e+00	Retreg2
3	chr16	1541638	2934560	1	1	1.82e-07	4.11e-02	1.77e-08	Il17rd
4	chr17	61510864	62906219	1	1	9.21e-17	7.08e-02	1.61e-03	Ccny

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	434.72	2	1	25	0	1.00e+00	Il17rd Retreg2
BMI without tail	14318.02	3	1	25	1	1.58e-04	Ccny Retreg2 Serping1
Body weight	3.83	2	0	0	0	1.00e+00	Il17rd Retreg2
Epididymis fat weight	12101.13	2	2	50	0	1.00e+00	Ccny Retreg2
Glucose	541.77	1	1	25	0	1.00e+00	Retreg2
Heart weight	1537.52	2	1	25	0	1.00e+00	Retreg2 Serping1
Left kidney weight	18353.14	2	1	25	0	1.00e+00	Ccny Retreg2
Right kidney weight	13471.05	2	2	50	0	1.00e+00	Ccny Retreg2
Tail length	9645.98	2	1	25	0	1.00e+00	Retreg2 Serping1
Length with tail	496.7	2	1	25	0	1.00e+00	Il17rd Retreg2
Length without tail	11812.92	3	1	25	-1	4.69e-04	Ccny Il17rd Retreg2
Liver weight, left	1746.03	2	1	25	0	1.00e+00	Ccny Retreg2
Liver weight, right	25.83	2	1	25	0	1.00e+00	Il17rd Retreg2
Parametrial fat weight	181.56	1	1	25	0	1.00e+00	Retreg2
Retroperitoneal fat weight	1972.27	1	1	25	0	1.00e+00	Retreg2
Intraocular pressure	5196.88	1	1	25	0	1.00e+00	Retreg2
Extensor digitorum longus weight	1077.67	1	1	25	0	1.00e+00	Retreg2
Soleus weight	20.71	1	1	25	0	1.00e+00	Retreg2
Tibialis anterior weight	1158.38	1	1	25	0	1.00e+00	Retreg2
Tibia length	767.35	1	1	25	0	1.00e+00	Retreg2
Number of licking bursts	22481.66	2	1	25	0	1.00e+00	Retreg2 Serping1
Food consumed during 24 hour testing period	11841.69	2	1	25	0	1.00e+00	Ccny Retreg2
Times rat made contact with spout	71.66	1	1	25	0	1.00e+00	Retreg2
Mean time between licks in bursts	55818.77	1	1	25	0	1.00e+00	Retreg2
Mean num. licks in bursts	18923.26	2	1	25	0	1.00e+00	Retreg2 Serping1
Std. dev. time between licks in bursts	29750.31	1	1	25	0	1.00e+00	Retreg2
Water consumed over 24 hours	11394.56	2	1	25	0	1.00e+00	Ccny Retreg2
Patch foraging indifference point 0 sec	39171.5	1	1	25	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	16720.05	2	2	50	0	1.00e+00	Ccny Retreg2
Indifference point function ln k	18558.57	2	2	50	0	1.00e+00	Ccny Retreg2
Indifference point function log k	18558.57	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 0 sec	41947.04	1	1	25	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	1170.24	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 18 sec	20229.7	2	1	25	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 24 sec	24938.62	2	1	25	0	1.00e+00	Ccny Retreg2
Patch foraging total patch changes 6 sec	3901.9	2	1	25	0	1.00e+00	Ccny Retreg2
Patch foraging time to switch 0 sec	33252.55	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 0 sec	30218.69	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 12 sec	23559.87	2	2	50	0	1.00e+00	Ccny Retreg2
Patch foraging water rate 18 sec	16866.55	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 24 sec	1033.47	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 6 sec	430.39	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotor activity	17.21	1	0	0	0	1.00e+00	Ccny
Locomotor testing distance	9236.59	2	2	50	0	1.00e+00	Ccny Retreg2
Locomotor testing rearing	31714.06	1	1	25	0	1.00e+00	Retreg2
Light reinforcement 1	16591.1	3	2	50	-1	5.19e-04	Ccny Retreg2 Serping1
Light reinforcement 2	12263.98	2	2	50	0	1.00e+00	Ccny Retreg2
Reaction time number correct	21164.32	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time mean minus median	59987.58	1	1	25	0	1.00e+00	Retreg2
Reaction time mean minus median AUC	62008.13	1	1	25	0	1.00e+00	Retreg2
Reaction time num false alarms	15357.42	1	1	25	0	1.00e+00	Retreg2
Reaction time num false alarms AUC	11675.48	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time trials correct on left	21164.32	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time trials on left	20302.27	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time mean	14869.21	1	1	25	0	1.00e+00	Retreg2
Reaction time mean AUC	19391.48	1	1	25	0	1.00e+00	Retreg2
Median of all reaction times	3951.2	1	1	25	0	1.00e+00	Retreg2
Reaction time omissions	8364.84	1	1	25	0	1.00e+00	Retreg2
Reaction time false alarm rate	210.6	1	1	25	0	1.00e+00	Retreg2
Reaction time premature initiation rate	9733.76	1	1	25	0	1.00e+00	Retreg2
Reaction time premature initiations	26876.79	1	1	25	0	1.00e+00	Retreg2
Std. dev. reaction times	30441.62	1	1	25	0	1.00e+00	Retreg2
Reaction time trials completed	20302.27	2	1	25	0	1.00e+00	Ccny Retreg2
Reaction time trials AUC	20717.99	2	1	25	0	1.00e+00	Ccny Retreg2
Social response proportion	4391.45	2	1	25	0	1.00e+00	Retreg2 Serping1
Social responses	427.84	3	1	25	0	1.00e+00	Ccny Retreg2 Serping1
Social time	5827.82	2	1	25	0	1.00e+00	Retreg2 Serping1
Conditioned locomotion	1400.08	1	1	25	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	9573.48	1	1	25	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	9294.65	1	1	25	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	25	0	1.00e+00	Retreg2
Saline control response	3160.68	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	7264.28	2	1	25	0	1.00e+00	Il17rd Retreg2
Condit. Reinf. active-inactive response ratio	14360.84	2	1	25	0	1.00e+00	Il17rd Retreg2
Condit. Reinf. active responses	2302.04	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	10889.7	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	3863.86	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. lever reinforcers received	469.54	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	2531.81	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	13282.18	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	19908.31	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. index score	12744.53	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	16150.81	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	5331.08	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	4012.39	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	17498.16	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	11800.43	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	1164.95	1	1	25	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	33606.64	2	1	25	0	1.00e+00	Ccny Retreg2
Conditioned reinforcement - inactives	16224.25	3	1	25	1	3.22e-04	Ccny Il17rd Retreg2
Conditioned locomotion	5175.07	2	1	25	0	1.00e+00	Ccny Retreg2
Intermittent access intake day 1-15 change	42631.8	2	1	25	0	1.00e+00	Ccny Retreg2
Intermittent access intake escalation	63041.97	1	1	25	0	1.00e+00	Retreg2
Intermittent access intake escalation 2	18103.13	2	2	50	0	1.00e+00	Ccny Retreg2
Intermitt. access day 1 inactive lever presses	60216.09	2	1	25	0	1.00e+00	Ccny Retreg2
Intermitt. access day 15 inactive lever presses	61819.85	1	1	25	0	1.00e+00	Retreg2
Intermitt. access escalation Index	46654.4	1	1	25	0	1.00e+00	Retreg2
Intermittent access day 1 total infusions	22044.9	2	1	25	0	1.00e+00	Il17rd Retreg2
Intermittent access day 15 total infusions	16247.46	2	1	25	0	1.00e+00	Il17rd Retreg2
Intermittent access terminal intake (last 3 days)	12403.19	2	1	25	0	1.00e+00	Il17rd Retreg2
Intermittent access total infusions	93.49	2	1	25	0	1.00e+00	Ccny Retreg2
Intermittent access day 1 locomotion	8747.53	3	1	25	-1	2.03e-06	Ccny Il17rd Retreg2
Intermittent access day 15 total locomotion	28527.57	2	2	50	0	1.00e+00	Ccny Retreg2
Intermittent access total locomotion	116.36	1	1	25	0	1.00e+00	Retreg2
Intermittent access standard deviation	38000.64	2	2	50	0	1.00e+00	Ccny Retreg2
Cocaine induced anxiety	23042.16	2	1	25	0	1.00e+00	Ccny Retreg2
Post-drug Anxiety	4753.56	1	1	25	0	1.00e+00	Retreg2
Baseline Anxiety	16763.76	2	1	25	0	1.00e+00	Ccny Retreg2
Lifetime Intake	834.23	2	1	25	0	1.00e+00	Ccny Retreg2
Incentive Sensitization - Responses	23792.94	2	1	25	0	1.00e+00	Ccny Retreg2
Incentive Sensitization - Breakpoint	18433.51	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 active lever presses	10669.41	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 breakpoint	10106.03	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 1 inactive lever presses	20741.76	2	1	25	0	1.00e+00	Il17rd Retreg2
Progressive ratio test 2 active lever presses	5095.75	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 breakpoint	4281.49	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio test 2 inactive lever presses	24174.5	2	1	25	0	1.00e+00	Ccny Retreg2
Total sessions with >9 infusions	991.35	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 1 total inactive lever presses	13141.08	2	1	25	0	1.00e+00	Ccny Retreg2
Short access day 10 total inactive lever presses	46304.57	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 1 total infusions	12823.56	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 10 total infusions	22696.46	1	1	25	0	1.00e+00	Retreg2
Short access total infusions	4403.04	2	2	50	0	1.00e+00	Ccny Retreg2
Short access day 1 locomotion	12408.48	2	1	25	0	1.00e+00	Ccny Retreg2
Short access day 10 total locomotion	44097.22	1	1	25	0	1.00e+00	Retreg2
Short access total locomotion	18677.85	1	1	25	0	1.00e+00	Retreg2
Compulsive drug intake	9342.82	1	1	25	0	1.00e+00	Retreg2
One hour access (0.3 mA shock)	1168.72	2	1	25	0	1.00e+00	Ccny Retreg2
One hour access (shock baseline)	27499.57	1	1	25	0	1.00e+00	Retreg2
Number of responses in last shaping day	4549.9	2	1	25	0	1.00e+00	Ccny Retreg2
Context. condit. distance diff. score	212.47	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 1	3523.61	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 1	516.6	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 2	2158.08	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 2	258.34	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion velocity, session 3	507.49	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 3	4009.46	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	1361.96	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	2872.44	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 7	150.5	2	1	25	0	1.00e+00	Il17rd Retreg2
Locomotion distance, session 7	431.03	2	1	25	0	1.00e+00	Retreg2 Serping1
Stereotopy head waving bouts, day 7	2509.72	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 7	2115.93	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 8	210.06	2	1	25	0	1.00e+00	Il17rd Retreg2
Locomotion distance, session 8	147.88	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization distance	3670.85	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	2042.98	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	957.65	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	242.03	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	2765.7	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	4681.39	1	1	25	0	1.00e+00	Retreg2
Incentive salience index mean	3540.72	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	5282.33	1	1	25	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 1	5589.03	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	9232.79	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	429.72	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 1	394.1	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	266.96	1	1	25	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	5880.03	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	3159.16	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	63.93	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, hab. session 2	22.17	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 2	31.27	1	1	25	0	1.00e+00	Retreg2
Novel to familiar place preference ratio	15339.58	1	1	25	0	1.00e+00	Retreg2
Novelty place preference	14927.56	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, NPP test	10685.62	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, NPP test	1935.62	1	1	25	0	1.00e+00	Retreg2
Total locomotion distance, NPP test	1687.31	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	479.14	2	1	25	0	1.00e+00	Ccny Retreg2
Pavlov. Cond. lever latency	491.79	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	1037.76	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. index score	384.43	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	404.63	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	677.08	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	491.61	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	123.55	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	418.89	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	583.93	1	1	25	0	1.00e+00	Retreg2
Bone: apparent density	5461.77	1	1	25	0	1.00e+00	Retreg2
Bone surface	6197.68	1	1	25	0	1.00e+00	Retreg2
Bone volume	8624.75	1	1	25	0	1.00e+00	Retreg2
Bone: connectivity density	1667.52	1	1	25	0	1.00e+00	Retreg2
Bone: cortical apparent density	12020.36	1	1	25	0	1.00e+00	Retreg2
Bone: cortical area	4581.96	1	1	25	0	1.00e+00	Retreg2
Bone: cortical porosity	432.96	1	1	25	0	1.00e+00	Retreg2
Bone: cortical porosity	1113.18	1	1	25	0	1.00e+00	Retreg2
Bone: cortical thickness	374.52	1	1	25	0	1.00e+00	Retreg2
Bone: cortical thickness	2918.77	1	1	25	0	1.00e+00	Retreg2
Bone: cortical tissue density	13002.58	1	1	25	0	1.00e+00	Retreg2
Bone: elastic displacement	2539.53	2	1	25	0	1.00e+00	Il17rd Retreg2
Bone: elastic work	361.86	1	1	25	0	1.00e+00	Retreg2
Bone: endosteal estimation	4460.32	2	1	25	0	1.00e+00	Il17rd Retreg2
Bone: endosteal perimeter	11863.6	1	1	25	0	1.00e+00	Retreg2
Bone: final force	1600.36	1	1	25	0	1.00e+00	Retreg2
Bone: final moment	219.15	1	1	25	0	1.00e+00	Retreg2
Bone: marrow area	4718.45	2	1	25	0	1.00e+00	Il17rd Retreg2
Bone: maximum diameter	6068.73	1	1	25	0	1.00e+00	Retreg2
Bone: maximum force	8697.09	1	1	25	0	1.00e+00	Retreg2
Bone: maximum moment	5989.29	1	1	25	0	1.00e+00	Retreg2
Bone: minimum diameter	2053.43	2	1	25	0	1.00e+00	Il17rd Retreg2
Bone: periosteal estimation	4898.09	2	1	25	0	1.00e+00	Il17rd Retreg2
Bone: periosteal perimeter	11400.25	1	1	25	0	1.00e+00	Retreg2
Bone: post-yield work	13672.98	1	1	25	0	1.00e+00	Retreg2
Bone: stiffness	4520.29	2	1	25	0	1.00e+00	Il17rd Retreg2
Bone: tissue strength	2995.95	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular number	10739.78	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular spacing	7952.12	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular thickness	8476.26	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular tissue density	14554.51	1	1	25	0	1.00e+00	Retreg2
LgA early post infusion interval	17795.39	2	2	50	0	1.00e+00	Ccny Retreg2
LgA late post infusion interval	17466.28	2	1	25	0	1.00e+00	Retreg2 Serping1
LgA early loading	36388.2	2	1	25	0	1.00e+00	Retreg2 Serping1
LgA late loading	27855.13	4	1	25	1	1.15e-06	Ccny Il17rd Retreg2 Serping1
LgA early average infusions	7312.1	3	1	25	1	2.86e-05	Ccny Retreg2 Serping1
LgA late average infusions	21032.27	2	2	50	0	1.00e+00	Retreg2 Serping1
LgA early timeout	6032.01	2	1	25	0	1.00e+00	Retreg2 Serping1
LgA late timeout	29427.52	1	1	25	0	1.00e+00	Retreg2
LgA early titration	31218.74	1	1	25	0	1.00e+00	Retreg2
LgA late titration	22567.99	2	2	50	0	1.00e+00	Retreg2 Serping1
LgA total infusion	10151.84	3	2	50	1	5.68e-05	Ccny Retreg2 Serping1
LgA PC1 addiction-like behavior	35050.51	2	2	50	0	1.00e+00	Retreg2 Serping1
ShA PR total presses	11205.63	2	1	25	0	1.00e+00	Il17rd Retreg2
LgA PR total presses	2191.2	3	2	50	0	1.00e+00	Ccny Retreg2 Serping1
ShA early post infusion interval	4040.41	2	1	25	0	1.00e+00	Retreg2 Serping1
ShA late post infusion interval	153.92	2	1	25	0	1.00e+00	Ccny Retreg2
ShA early loading	76.18	2	1	25	0	1.00e+00	Ccny Retreg2
ShA late loading	18924.64	2	1	25	0	1.00e+00	Retreg2 Serping1
ShA early average infusions	6494.89	3	2	50	0	1.00e+00	Ccny Retreg2 Serping1
ShA late average infusions	4443.18	2	1	25	0	1.00e+00	Retreg2 Serping1
ShA early timeout	180.07	3	1	25	0	1.00e+00	Ccny Retreg2 Serping1
ShA late timeout	18424.65	1	1	25	0	1.00e+00	Retreg2
ShA early titration	510.75	3	2	50	0	1.00e+00	Ccny Retreg2 Serping1
ShA late titration	3823.44	3	1	25	0	1.00e+00	Ccny Retreg2 Serping1
ShA total infusions	12428.49	2	1	25	0	1.00e+00	Retreg2 Serping1
Total infusions	7194.96	3	2	50	1	1.11e-04	Ccny Retreg2 Serping1
Breakpoint value in progressive ratio session	18806.07	1	1	25	0	1.00e+00	Retreg2
Distance traveled before self-admin	12642.74	3	1	25	1	4.69e-04	Ccny Retreg2 Serping1
Distance traveled after self-admin	16247.09	2	2	50	0	1.00e+00	Ccny Retreg2
Delta time in closed arm before/after self-admin	188.99	2	2	50	0	1.00e+00	Ccny Retreg2
Delta time in open arm before/after self-admin	3790.09	3	1	25	1	7.70e-04	Ccny Il17rd Retreg2
Diff in mean of infusions in LGA sessions	18330.27	1	1	25	0	1.00e+00	Retreg2
Extinction: sum of active levers before priming	14208.81	2	2	50	0	1.00e+00	Ccny Retreg2
Active lever presses in extinction session 6	393.1	2	2	50	0	1.00e+00	Ccny Retreg2
Delta distance traveled before/after self-admin	597.98	4	1	25	-1	8.24e-05	Ccny Il17rd Retreg2 Serping1
Delta ambulatory time before/after self-admin	6183.48	4	2	50	-1	1.42e-05	Ccny Il17rd Retreg2 Serping1
Time in closed arm before self-admin	8961.66	3	1	25	0	1.00e+00	Ccny Retreg2 Serping1
Time in closed arm after self-admin	1553.4	3	2	50	0	1.00e+00	Ccny Il17rd Retreg2
Time in open arm before self-admin	2199.06	3	2	50	-1	2.87e-03	Ccny Retreg2 Serping1
Time in open arm after self-admin	243.22	2	1	25	0	1.00e+00	Ccny Retreg2
Sum of active levers in priming session hrs 5-6	493.26	2	1	25	0	1.00e+00	Retreg2 Serping1
Time to tail flick, vehicle, before self-admin	4491.15	3	2	50	0	1.00e+00	Ccny Il17rd Retreg2
Time to tail flick, vehicle, after self-admin	8457.14	4	2	50	1	6.83e-05	Ccny Il17rd Retreg2 Serping1
Time to tail flick, test, before self-admin	8139.55	1	1	25	0	1.00e+00	Retreg2
Time to tail flick, test, after self-admin	711.65	2	1	25	0	1.00e+00	Ccny Retreg2
Delta time to tail flick, vehicle, before/after SA	2482.85	3	3	75	0.99	6.96e-03	Ccny Retreg2 Serping1
Delta time to tail flick, test, before/after SA	15684.59	1	1	25	0	1.00e+00	Retreg2
Ambulatory time before self-admin	19733.46	3	2	50	1	4.52e-04	Ccny Retreg2 Serping1
Ambulatory time after self-admin	13316.09	2	1	25	0	1.00e+00	Ccny Retreg2
Total heroin consumption	134.58	2	2	50	0	1.00e+00	Ccny Retreg2
Area under the delay curve	12400.77	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 0s delay	2159.25	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 16s delay	7326.74	3	1	25	0	1.00e+00	Ccny Il17rd Retreg2
Delay disc. indifference point, 2s delay	155.27	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 24s delay	16227.16	2	1	25	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 4s delay	314.57	2	1	25	0	1.00e+00	Ccny Retreg2
Delay disc. indifference point, 8s delay	16687.74	1	1	25	0	1.00e+00	Retreg2
Delay discount exponential model param	8465.31	1	1	25	0	1.00e+00	Retreg2
Delay discount hyperbolic model param	6142.92	1	1	25	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	30605.7	1	1	25	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	2856.56	2	2	50	0	1.00e+00	Ccny Retreg2
Time >=10cm from walls, locomotor time 1	3258.84	3	1	25	-1	1.98e-04	Ccny Retreg2 Serping1
Bouts of movement, locomotor time 1	5409.06	2	2	50	0	1.00e+00	Ccny Retreg2
Total resting periods, locomotor time 1	1407.78	2	1	25	0	1.00e+00	Ccny Retreg2
Rest time, locomotor task time 1	11180.79	2	1	25	0	1.00e+00	Retreg2 Serping1
Distance moved, locomotor task time 1	13774.33	4	2	50	-1	8.72e-06	Ccny Il17rd Retreg2 Serping1
Vertical activity count, locomotor time 1	35599.3	3	2	50	-1	2.69e-05	Il17rd Retreg2 Serping1
Time >=10cm from walls, locomotor time 2	17795.33	3	1	25	1	4.03e-04	Ccny Retreg2 Serping1
Bouts of movement, locomotor time 2	20518.21	3	2	50	1	7.46e-06	Ccny Retreg2 Serping1
Total resting periods, locomotor time 2	24771.89	3	2	50	1	1.21e-05	Ccny Retreg2 Serping1
Rest time, locomotor task time 2	12754.88	1	1	25	0	1.00e+00	Retreg2
Distance moved, locomotor task time 2	2128.71	4	2	50	1	2.72e-03	Ccny Il17rd Retreg2 Serping1
Vertical activity count, locomotor time 2	17860.42	3	1	25	0	1.00e+00	Ccny Retreg2 Serping1
Weight adjusted by age	23604.59	2	2	50	0	1.00e+00	Ccny Retreg2
Seeking ratio, delayed vs. immediate footshock	4488.58	3	1	25	0	1.00e+00	Ccny Il17rd Retreg2
Locomotion in novel chamber	1954.56	2	1	25	0	1.00e+00	Ccny Retreg2
Locomotion in novel chamber post-restriction	21811.65	2	1	25	0	1.00e+00	Ccny Retreg2
Progressive ratio	16980.34	3	2	50	-1	5.81e-04	Ccny Retreg2 Serping1
Food seeking constrained by brief footshock	940.78	2	1	25	0	1.00e+00	Il17rd Retreg2
Seeking ratio, punishment vs. effort	20643.93	2	1	25	0	1.00e+00	Ccny Retreg2
Run reversals in cocaine runway, females	3143.01	3	1	25	0	1.00e+00	Il17rd Retreg2 Serping1
Run reversals in cocaine runway, males	3835.75	1	1	25	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway	8153.9	2	1	25	0	1.00e+00	Ccny Retreg2
Latency to leave start box in cocaine runway, F	7166.92	1	1	25	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, M	591.02	3	2	50	0	1.00e+00	Ccny Retreg2 Serping1
Co content in liver	1133.25	1	1	25	0	1.00e+00	Retreg2
Cu content in liver	39.92	1	1	25	0	1.00e+00	Retreg2
Fe content in liver	1344.53	1	1	25	0	1.00e+00	Retreg2
K content in liver	1519.62	1	1	25	0	1.00e+00	Retreg2
Mg content in liver	6026.97	1	1	25	0	1.00e+00	Retreg2
Mn content in liver	1009.39	1	1	25	0	1.00e+00	Retreg2
Na content in liver	4018.36	1	1	25	0	1.00e+00	Retreg2
Rb content in liver	87.87	1	1	25	0	1.00e+00	Retreg2
Zn content in liver	1880.53	2	1	25	0	1.00e+00	Il17rd Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.1
Adipose	alternative TSS	0	0	1.06
Adipose	gene expression	0	0	1
Adipose	isoform ratio	0	0	1.03
Adipose	intron excision ratio	0	0	1.03
Adipose	mRNA stability	1	0	1.01
BLA	alternative polyA	0	0	1.11
BLA	alternative TSS	0	0	1.06
BLA	gene expression	0	0	1.02
BLA	isoform ratio	0	0	1.08
BLA	intron excision ratio	0	0	1.08
BLA	mRNA stability	0	0	1.03
Brain	alternative polyA	0	0	1.04
Brain	alternative TSS	0	0	1.02
Brain	gene expression	0	0	1.01
Brain	isoform ratio	0	0	1.02
Brain	intron excision ratio	0	0	1.04
Brain	mRNA stability	0	0	1.03
Eye	alternative polyA	0	0	1.08
Eye	alternative TSS	0	0	1
Eye	gene expression	0	0	1.03
Eye	isoform ratio	0	0	1.07
Eye	intron excision ratio	0	0	1.01
Eye	mRNA stability	0	0	1.05
IC	alternative polyA	0	0	1.03
IC	alternative TSS	0	0	1.02
IC	gene expression	0	0	1.01
IC	isoform ratio	0	0	1.07
IC	intron excision ratio	0	0	1.08
IC	mRNA stability	0	0	1
IL	alternative polyA	0	0	1
IL	alternative TSS	0	0	0.98
IL	gene expression	0	0	1.02
IL	isoform ratio	0	0	0.97
IL	intron excision ratio	0	0	1.15
IL	mRNA stability	0	0	1.03
LHb	alternative polyA	0	0	1.15
LHb	alternative TSS	0	0	1.14
LHb	gene expression	0	0	0.98
LHb	isoform ratio	0	0	1.13
LHb	intron excision ratio	0	0	1.18
LHb	mRNA stability	0	0	0.97
Liver	alternative polyA	0	0	1.03
Liver	alternative TSS	0	0	1.06
Liver	gene expression	0	0	1.01
Liver	isoform ratio	1	0	1
Liver	intron excision ratio	0	0	1.01
Liver	mRNA stability	0	0	1.02
NAcc	alternative polyA	2	0.1	64.91
NAcc	alternative TSS	0	0	1.05
NAcc	gene expression	0	0	1.01
NAcc	isoform ratio	0	0	1.03
NAcc	intron excision ratio	0	0	1.03
NAcc	mRNA stability	0	0	1.04
OFC	alternative polyA	0	0	1.05
OFC	alternative TSS	0	0	1.03
OFC	gene expression	0	0	0.99
OFC	isoform ratio	0	0	1.05
OFC	intron excision ratio	0	0	1.14
OFC	mRNA stability	0	0	0.97
PL	alternative polyA	0	0	1.01
PL	alternative TSS	0	0	1.07
PL	gene expression	0	0	1.02
PL	isoform ratio	0	0	1.06
PL	intron excision ratio	0	0	1.02
PL	mRNA stability	0	0	1.01
pVTA	alternative polyA	0	0	1.06
pVTA	alternative TSS	0	0	1.1
pVTA	gene expression	1	0	1.04
pVTA	isoform ratio	0	0	1.07
pVTA	intron excision ratio	0	0	1.04
pVTA	mRNA stability	0	0	1.04
RMTg	alternative polyA	0	0	1.19
RMTg	alternative TSS	0	0	1.03
RMTg	gene expression	0	0	0.99
RMTg	isoform ratio	0	0	1.03
RMTg	intron excision ratio	0	0	1.05
RMTg	mRNA stability	0	0	0.99