Hub : Traits

ShA early loading

The total sum of the number of infusions taken in the first 10 minutes of days 1-3 of short access

Tags: Behavior · Cocaine

Project: u01_olivier_george_cocaine

4 loci · 4 genes with independent associations · 4 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr1	106304569	107278380	1	1	1.67e-07	3.57e-03	2.94e-09	Tsg101
2	chr7	53106722	54501245	1	1	9.84e-09	2.03e-02	1.61e-01	LOC120093595
3	chr7	92127461	93066096	1	1	7.60e-13	2.30e-01	1.00e+00	Ndufb9
4	chr9	83390749	84777604	1	1	5.39e-31	2.02e-01	1.00e+00	Retreg2

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	294.03	3	2	50	0	1.00e+00	LOC120093595 Ndufb9 Retreg2
BMI without tail	19087.44	3	2	50	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Body weight	5.37	4	1	25	0.21	7.94e-01	LOC120093595 Ndufb9 Retreg2 Tsg101
Epididymis fat weight	12097.97	3	2	50	0	1.00e+00	LOC120093595 Ndufb9 Retreg2
Glucose	273.97	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Heart weight	1536.76	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Left kidney weight	27527.72	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Right kidney weight	20206.48	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Tail length	14460.46	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Length with tail	746.74	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Length without tail	23620.64	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Liver weight, left	1747.19	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Liver weight, right	26.54	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Parametrial fat weight	92.13	2	1	25	0	1.00e+00	LOC120093595 Retreg2
Retroperitoneal fat weight	1973.32	2	2	50	0	1.00e+00	LOC120093595 Retreg2
Intraocular pressure	5195.51	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Extensor digitorum longus weight	1077.67	1	1	25	0	1.00e+00	Retreg2
Soleus weight	12.63	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Tibialis anterior weight	1158.38	1	1	25	0	1.00e+00	Retreg2
Tibia length	385.43	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Number of licking bursts	67424.86	1	1	25	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	35509.41	1	1	25	0	1.00e+00	Retreg2
Times rat made contact with spout	41.61	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Mean time between licks in bursts	55817.09	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Mean num. licks in bursts	56750.08	1	1	25	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	29750.31	1	1	25	0	1.00e+00	Retreg2
Water consumed over 24 hours	34168.6	1	1	25	0	1.00e+00	Retreg2
Patch foraging indifference point 0 sec	39171.5	1	1	25	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	25072.33	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Indifference point function ln k	27852.12	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Indifference point function log k	27852.12	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 0 sec	41947.04	1	1	25	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	1174.88	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 18 sec	20233.2	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 24 sec	37448.01	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 6 sec	3903.01	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Patch foraging time to switch 0 sec	33254.99	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 0 sec	30219.01	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 12 sec	70639.93	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 18 sec	16866.98	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 24 sec	1033.47	1	1	25	0	1.00e+00	Retreg2
Patch foraging water rate 6 sec	293.24	3	2	50	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Locomotor activity	4.13	1	0	0	0	1.00e+00	Ndufb9
Locomotor testing distance	13837.71	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Locomotor testing rearing	31701.02	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Light reinforcement 1	66311.75	1	1	25	0	1.00e+00	Retreg2
Light reinforcement 2	18371.56	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Reaction time number correct	31744.5	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Reaction time mean minus median	39986.04	3	1	25	0	1.00e+00	LOC120093595 Ndufb9 Retreg2
Reaction time mean minus median AUC	62002.11	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Reaction time num false alarms	15357.42	1	1	25	0	1.00e+00	Retreg2
Reaction time num false alarms AUC	35016.83	1	1	25	0	1.00e+00	Retreg2
Reaction time trials correct on left	31744.5	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Reaction time trials on left	30449.82	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Reaction time mean	29724.21	1	1	25	0	1.00e+00	Retreg2
Reaction time mean AUC	38768	1	1	25	0	1.00e+00	Retreg2
Median of all reaction times	7893.84	1	1	25	0	1.00e+00	Retreg2
Reaction time omissions	4186.04	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Reaction time false alarm rate	73.62	3	1	25	0	1.00e+00	LOC120093595 Ndufb9 Retreg2
Reaction time premature initiation rate	9733.76	1	1	25	0	1.00e+00	Retreg2
Reaction time premature initiations	53743.58	1	1	25	0	1.00e+00	Retreg2
Std. dev. reaction times	30435.18	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Reaction time trials completed	30449.82	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Reaction time trials AUC	31071.82	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Social response proportion	8777.03	1	1	25	0	1.00e+00	Retreg2
Social responses	635.8	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Social time	11650.06	1	1	25	0	1.00e+00	Retreg2
Conditioned locomotion	1400.08	1	1	25	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	19128.47	1	1	25	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	18571.31	1	1	25	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	25	0	1.00e+00	Retreg2
Saline control response	3160.68	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	14521.56	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	14360.59	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active responses	2302.04	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	10889.7	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	1935.17	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. lever reinforcers received	469.54	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	2531.81	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	13282.18	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	19909.31	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. index score	12744.53	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	16150.81	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	5331.08	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	4012.39	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	34989.79	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	11800.43	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	1164.95	1	1	25	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	33615.83	3	2	50	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Conditioned reinforcement - inactives	32455.53	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Conditioned locomotion	5202.57	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Intermittent access intake day 1-15 change	63940.46	2	1	25	0	1.00e+00	Retreg2 Tsg101
Intermittent access intake escalation	63036.64	2	1	25	0	1.00e+00	Retreg2 Tsg101
Intermittent access intake escalation 2	18091.28	2	1	25	0	1.00e+00	Retreg2 Tsg101
Intermitt. access day 1 inactive lever presses	90309.52	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Intermitt. access day 15 inactive lever presses	61868.22	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Intermitt. access escalation Index	31104.9	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Intermittent access day 1 total infusions	66115.79	1	1	25	0	1.00e+00	Retreg2
Intermittent access day 15 total infusions	24368.95	2	1	25	0	1.00e+00	Retreg2 Tsg101
Intermittent access terminal intake (last 3 days)	12403.01	2	1	25	0	1.00e+00	Retreg2 Tsg101
Intermittent access total infusions	181.04	1	1	25	0	1.00e+00	Retreg2
Intermittent access day 1 locomotion	34964.22	1	1	25	0	1.00e+00	Retreg2
Intermittent access day 15 total locomotion	85548.8	1	1	25	0	1.00e+00	Retreg2
Intermittent access total locomotion	44.85	3	1	25	0	1.00e+00	LOC120093595 Ndufb9 Retreg2
Intermittent access standard deviation	56983.21	2	1	25	0	1.00e+00	Retreg2 Tsg101
Cocaine induced anxiety	34589.88	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Post-drug Anxiety	2390.18	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Baseline Anxiety	16852.64	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Lifetime Intake	1655.49	1	1	25	0	1.00e+00	Retreg2
Incentive Sensitization - Responses	35692.61	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Incentive Sensitization - Breakpoint	27649.77	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 1 active lever presses	15996.07	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 1 breakpoint	15154.62	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 1 inactive lever presses	31117.61	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 2 active lever presses	7635.38	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 2 breakpoint	4274.2	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 2 inactive lever presses	24172.08	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Total sessions with >9 infusions	1959.63	1	1	25	0	1.00e+00	Retreg2
Short access day 1 total inactive lever presses	19719.11	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Short access day 10 total inactive lever presses	69422.81	2	1	25	0	1.00e+00	Retreg2 Tsg101
Short access day 1 total infusions	38385.19	1	1	25	0	1.00e+00	Retreg2
Short access day 10 total infusions	11359.78	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Short access total infusions	4392.75	2	1	25	0	1.00e+00	Retreg2 Tsg101
Short access day 1 locomotion	12422.14	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Short access day 10 total locomotion	44090.11	2	1	25	0	1.00e+00	LOC120093595 Retreg2
Short access total locomotion	9343.18	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Compulsive drug intake	9346.2	2	1	25	0	1.00e+00	Ndufb9 Retreg2
One hour access (0.3 mA shock)	1167.82	2	1	25	0	1.00e+00	Ndufb9 Retreg2
One hour access (shock baseline)	54988.81	1	1	25	0	1.00e+00	Retreg2
Number of responses in last shaping day	13618.48	1	1	25	0	1.00e+00	Retreg2
Context. condit. distance diff. score	212.47	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 1	1769.63	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Locomotion distance, session 1	1024.77	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 2	2158.08	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 2	508.11	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 3	507.49	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 3	4009.46	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	1361.96	1	1	25	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	2872.44	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, session 7	292.79	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 7	435.3	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving bouts, day 7	1279.33	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving duration, day 7	1081.37	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Locomotion velocity, session 8	409.23	1	1	25	0	1.00e+00	Retreg2
Locomotion distance, session 8	147.88	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization distance	3670.85	1	1	25	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	1029.63	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active minus inactive responses	482.97	2	1	25	0	1.00e+00	LOC120093595 Retreg2
Condit. Reinf. active-inactive response ratio	242.03	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. active responses	2765.7	1	1	25	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	2347.53	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Incentive salience index mean	1774.72	2	1	25	0	1.00e+00	LOC120093595 Retreg2
Condit. Reinf. lever presses	2644.24	2	1	25	0	1.00e+00	LOC120093595 Retreg2
Time in familiar zone, hab. session 1	11168.49	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	9232.79	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	221.7	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 1	394.1	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	266.96	1	1	25	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	5880.03	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	6311.49	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	35.66	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 2	22.17	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 2	31.27	1	1	25	0	1.00e+00	Retreg2
Novel to familiar place preference ratio	15339.58	1	1	25	0	1.00e+00	Retreg2
Novelty place preference	14927.56	1	1	25	0	1.00e+00	Retreg2
Time in novel zone, NPP test	10685.62	1	1	25	0	1.00e+00	Retreg2
Total zone transitions, NPP test	980.79	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, NPP test	1687.31	1	1	25	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	953.07	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	248.61	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. change in total contacts	1037.76	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. index score	384.43	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	404.63	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	344.19	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. magazine entry number	491.61	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	69.21	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	418.89	1	1	25	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	583.93	1	1	25	0	1.00e+00	Retreg2
Bone: apparent density	2735.95	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone surface	6197.68	1	1	25	0	1.00e+00	Retreg2
Bone volume	8624.75	1	1	25	0	1.00e+00	Retreg2
Bone: connectivity density	841.82	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical apparent density	6014.36	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical area	2293.91	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	221.79	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	560.57	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical thickness	128.93	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Bone: cortical thickness	979.71	3	1	25	0	1.00e+00	LOC120093595 Ndufb9 Retreg2
Bone: cortical tissue density	6505.97	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: elastic displacement	7604.03	1	1	25	0	1.00e+00	Retreg2
Bone: elastic work	361.86	1	1	25	0	1.00e+00	Retreg2
Bone: endosteal estimation	4460.13	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: endosteal perimeter	11863.6	1	1	25	0	1.00e+00	Retreg2
Bone: final force	1600.36	1	1	25	0	1.00e+00	Retreg2
Bone: final moment	219.15	1	1	25	0	1.00e+00	Retreg2
Bone: marrow area	4718.77	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum diameter	2026.01	3	1	25	0	1.00e+00	LOC120093595 Ndufb9 Retreg2
Bone: maximum force	8697.09	1	1	25	0	1.00e+00	Retreg2
Bone: maximum moment	2996.54	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bone: minimum diameter	4100.86	1	1	25	0	1.00e+00	Retreg2
Bone: periosteal estimation	9791.57	1	1	25	0	1.00e+00	Retreg2
Bone: periosteal perimeter	11400.25	1	1	25	0	1.00e+00	Retreg2
Bone: post-yield work	13672.98	1	1	25	0	1.00e+00	Retreg2
Bone: stiffness	9032.86	1	1	25	0	1.00e+00	Retreg2
Bone: tissue strength	2995.95	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular number	5387.39	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular spacing	3988.39	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular thickness	8476.26	1	1	25	0	1.00e+00	Retreg2
Bone: trabecular tissue density	7288.68	2	2	50	0	1.00e+00	Ndufb9 Retreg2
LgA early post infusion interval	13352.55	4	2	50	0.99	6.13e-03	LOC120093595 Ndufb9 Retreg2 Tsg101
LgA late post infusion interval	8743.7	4	2	50	0.99	7.74e-03	LOC120093595 Ndufb9 Retreg2 Tsg101
LgA early loading	36381.47	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Tsg101
LgA late loading	46427.93	3	2	50	0	1.00e+00	LOC120093595 Ndufb9 Retreg2
LgA early average infusions	9743.54	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Tsg101
LgA late average infusions	31550.62	2	2	50	0	1.00e+00	Ndufb9 Retreg2
LgA early timeout	12057.77	1	1	25	0	1.00e+00	Retreg2
LgA late timeout	29424.99	2	1	25	0	1.00e+00	Ndufb9 Retreg2
LgA early titration	15624.75	4	2	50	-0.99	6.26e-03	LOC120093595 Ndufb9 Retreg2 Tsg101
LgA late titration	22564.93	3	2	50	0	1.00e+00	Ndufb9 Retreg2 Tsg101
LgA total infusion	13537.87	3	2	50	0	1.00e+00	LOC120093595 Ndufb9 Retreg2
LgA PC1 addiction-like behavior	35057.57	3	2	50	0	1.00e+00	LOC120093595 Ndufb9 Retreg2
ShA PR total presses	11213.89	2	1	25	0	1.00e+00	Ndufb9 Retreg2
LgA PR total presses	6491.94	1	1	25	0	1.00e+00	Retreg2
ShA early post infusion interval	4052.33	2	2	50	0	1.00e+00	Retreg2 Tsg101
ShA late post infusion interval	116.08	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Tsg101
ShA late loading	18923.13	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Tsg101
ShA early average infusions	4877.54	4	3	75	1	3.46e-03	LOC120093595 Ndufb9 Retreg2 Tsg101
ShA late average infusions	2964.91	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Tsg101
ShA early timeout	145	4	2	50	0.99	1.17e-02	LOC120093595 Ndufb9 Retreg2 Tsg101
ShA late timeout	9218.63	2	1	25	0	1.00e+00	Retreg2 Tsg101
ShA early titration	375.17	4	2	50	1	1.50e-03	LOC120093595 Ndufb9 Retreg2 Tsg101
ShA late titration	5734.72	2	1	25	0	1.00e+00	Ndufb9 Retreg2
ShA total infusions	12431.66	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Shock compulsivity	117768.67	1	1	25	0	1.00e+00	Retreg2
Total infusions	7200.68	4	2	50	-0.99	6.70e-03	LOC120093595 Ndufb9 Retreg2 Tsg101
Breakpoint value in progressive ratio session	37605.61	1	1	25	0	1.00e+00	Retreg2
Distance traveled before self-admin	25271.77	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Distance traveled after self-admin	32464.08	1	1	25	0	1.00e+00	Retreg2
Delta time in closed arm before/after self-admin	126.6	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Delta time in open arm before/after self-admin	7574.42	2	1	25	0	1.00e+00	Retreg2 Tsg101
Diff in mean of infusions in LGA sessions	18328.29	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Extinction: sum of active levers before priming	14206.81	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Active lever presses in extinction session 6	738.98	1	1	25	0	1.00e+00	Retreg2
Delta distance traveled before/after self-admin	992.44	3	2	50	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Delta ambulatory time before/after self-admin	15429.45	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Time in closed arm before self-admin	26866.11	1	1	25	0	1.00e+00	Retreg2
Time in closed arm after self-admin	2303.07	2	1	25	0	1.00e+00	Retreg2 Tsg101
Time in open arm before self-admin	4407.84	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Time in open arm after self-admin	182.09	3	2	50	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Sum of active levers in priming session hrs 5-6	496.26	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Time to tail flick, vehicle, before self-admin	6687.6	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Time to tail flick, vehicle, after self-admin	21081.01	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Time to tail flick, test, before self-admin	2732.02	3	2	50	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Time to tail flick, test, after self-admin	739.72	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Delta time to tail flick, vehicle, before/after SA	9805.78	1	1	25	0	1.00e+00	Retreg2
Delta time to tail flick, test, before/after SA	7848.65	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Ambulatory time before self-admin	78874.38	1	1	25	0	1.00e+00	Retreg2
Ambulatory time after self-admin	26614.91	1	1	25	0	1.00e+00	Retreg2
Total heroin consumption	240.55	1	1	25	0	1.00e+00	Retreg2
Area under the delay curve	24791.27	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 0s delay	2159.25	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 16s delay	21959.9	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 2s delay	155.27	1	1	25	0	1.00e+00	Retreg2
Delay disc. indifference point, 24s delay	16222.97	2	1	25	0	1.00e+00	Retreg2 Tsg101
Delay disc. indifference point, 4s delay	315.77	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Delay disc. indifference point, 8s delay	33362.4	1	1	25	0	1.00e+00	Retreg2
Delay discount exponential model param	16922.54	1	1	25	0	1.00e+00	Retreg2
Delay discount hyperbolic model param	12277.65	1	1	25	0	1.00e+00	Retreg2
Fecal boli incidents, locomotor time 1	61202.36	1	1	25	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	1902.79	3	2	50	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Time >=10cm from walls, locomotor time 1	6508.13	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Bouts of movement, locomotor time 1	5395.51	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Total resting periods, locomotor time 1	2793.59	1	1	25	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	11183.83	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Distance moved, locomotor task time 1	34443.92	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Vertical activity count, locomotor time 1	142354.07	1	1	25	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	71159.6	1	1	25	0	1.00e+00	Retreg2
Bouts of movement, locomotor time 2	82029.05	1	1	25	0	1.00e+00	Retreg2
Total resting periods, locomotor time 2	99042.67	1	1	25	0	1.00e+00	Retreg2
Rest time, locomotor task time 2	8507.09	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Distance moved, locomotor task time 2	2833.59	3	1	25	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Vertical activity count, locomotor time 2	26781.67	2	1	25	0	1.00e+00	Retreg2 Tsg101
Weight adjusted by age	35416.78	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, delayed vs. immediate footshock	4491.21	3	1	25	0	1.00e+00	LOC120093595 Retreg2 Tsg101
Locomotion in novel chamber	1993.33	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Locomotion in novel chamber post-restriction	32715.18	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio	22646.16	3	2	50	0	1.00e+00	Ndufb9 Retreg2 Tsg101
Food seeking constrained by brief footshock	476.11	4	1	25	0.99	1.02e-02	LOC120093595 Ndufb9 Retreg2 Tsg101
Seeking ratio, punishment vs. effort	13770.82	3	2	50	0	1.00e+00	LOC120093595 Ndufb9 Retreg2
Run reversals in cocaine runway, females	4708.79	2	1	25	0	1.00e+00	LOC120093595 Retreg2
Run reversals in cocaine runway, males	3884.61	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Latency to leave start box in cocaine runway	16290.75	1	1	25	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, F	3596.44	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Latency to leave start box in cocaine runway, M	867.32	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Co content in liver	1133.25	1	1	25	0	1.00e+00	Retreg2
Cu content in liver	28.08	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Fe content in liver	1344.53	1	1	25	0	1.00e+00	Retreg2
K content in liver	1519.62	1	1	25	0	1.00e+00	Retreg2
Mg content in liver	6026.97	1	1	25	0	1.00e+00	Retreg2
Mn content in liver	537.3	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Na content in liver	2013.84	2	1	25	0	1.00e+00	Ndufb9 Retreg2
Rb content in liver	71.08	2	2	50	0	1.00e+00	Ndufb9 Retreg2
Se content in liver	8.63	1	0	0	0	1.00e+00	Ndufb9
Zn content in liver	1887.46	2	2	50	0	1.00e+00	Ndufb9 Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	0.99
Adipose	alternative TSS	0	0	0.98
Adipose	gene expression	0	0	1.01
Adipose	isoform ratio	0	0	1.01
Adipose	intron excision ratio	0	0	0.93
Adipose	mRNA stability	1	0	1.03
BLA	alternative polyA	0	0	1.03
BLA	alternative TSS	0	0	1.02
BLA	gene expression	0	0	1.02
BLA	isoform ratio	0	0	0.98
BLA	intron excision ratio	0	0	0.92
BLA	mRNA stability	0	0	1.03
Brain	alternative polyA	0	0	1
Brain	alternative TSS	0	0	1
Brain	gene expression	0	0	1.03
Brain	isoform ratio	1	0	1.01
Brain	intron excision ratio	0	0	0.96
Brain	mRNA stability	0	0	1.03
Eye	alternative polyA	0	0	1.19
Eye	alternative TSS	0	0	0.81
Eye	gene expression	0	0	0.98
Eye	isoform ratio	0	0	1.01
Eye	intron excision ratio	0	0	0.9
Eye	mRNA stability	0	0	1.02
IC	alternative polyA	0	0	0.98
IC	alternative TSS	0	0	1.01
IC	gene expression	0	0	1.05
IC	isoform ratio	0	0	1.01
IC	intron excision ratio	0	0	0.93
IC	mRNA stability	0	0	1.04
IL	alternative polyA	0	0	0.98
IL	alternative TSS	0	0	1.11
IL	gene expression	0	0	1.02
IL	isoform ratio	0	0	0.99
IL	intron excision ratio	0	0	0.86
IL	mRNA stability	0	0	1.03
LHb	alternative polyA	0	0	1.06
LHb	alternative TSS	0	0	1.05
LHb	gene expression	0	0	0.98
LHb	isoform ratio	0	0	0.99
LHb	intron excision ratio	0	0	0.89
LHb	mRNA stability	0	0	1.05
Liver	alternative polyA	0	0	1.07
Liver	alternative TSS	0	0	0.97
Liver	gene expression	0	0	1.02
Liver	isoform ratio	0	0	1
Liver	intron excision ratio	0	0	1.05
Liver	mRNA stability	0	0	0.99
NAcc	alternative polyA	1	0	1.06
NAcc	alternative TSS	0	0	1.04
NAcc	gene expression	0	0	1.06
NAcc	isoform ratio	0	0	1
NAcc	intron excision ratio	0	0	1
NAcc	mRNA stability	0	0	1.04
OFC	alternative polyA	0	0	1.05
OFC	alternative TSS	0	0	1.17
OFC	gene expression	0	0	1.03
OFC	isoform ratio	0	0	1.06
OFC	intron excision ratio	0	0	0.93
OFC	mRNA stability	0	0	1.02
PL	alternative polyA	0	0	1.03
PL	alternative TSS	0	0	1.03
PL	gene expression	0	0	1.02
PL	isoform ratio	0	0	1
PL	intron excision ratio	0	0	0.98
PL	mRNA stability	0	0	1.05
pVTA	alternative polyA	0	0	1.03
pVTA	alternative TSS	0	0	1.02
pVTA	gene expression	0	0	1.04
pVTA	isoform ratio	0	0	1
pVTA	intron excision ratio	0	0	0.97
pVTA	mRNA stability	0	0	1.06
RMTg	alternative polyA	0	0	0.99
RMTg	alternative TSS	1	0.2	1.15
RMTg	gene expression	0	0	1.1
RMTg	isoform ratio	0	0	1
RMTg	intron excision ratio	0	0	0.95
RMTg	mRNA stability	0	0	1.06