Hub : Traits

LgA late loading

The total sum of the number of infusions taken in the first 10 minutes of days 11-14 of long access

Tags: Behavior · Cocaine

Project: u01_olivier_george_cocaine

3 loci · 3 genes with independent associations · 4 total associated genes

Significant Loci

#	Chr	Start pos	End pos	# assoc genes	# joint models	Best TWAS P	Best GWAS P	Cond GWAS P	Joint genes
1	chr2	144511896	145907690	1	1	1.19e-14	1.30e-02	1e+00	Mindy4b
2	chr7	92127461	93066096	1	1	6.88e-26	7.11e-01	1e+00	Ndufb9
3	chr9	83390749	84777604	2	1	0.00e+00	3.76e-01	1e+00	Retreg2

Pleiotropic Associations

Trait	Chi2 ratio	# genes+	# genes++	% genes++	Corr	Corr P	Genes
BMI with tail	296.8	3	3	100	0	1.00e+00	Mindy4b Ndufb9 Retreg2
BMI without tail	14321.63	3	2	66.7	1	3.29e-05	Mindy4b Ndufb9 Retreg2
Body weight	8.05	3	2	66.7	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Epididymis fat weight	12098.28	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Glucose	273.97	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Heart weight	1536.76	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Left kidney weight	13767.34	3	2	66.7	-1	9.01e-04	Mindy4b Ndufb9 Retreg2
Right kidney weight	13472.97	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Tail length	9645.91	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Length with tail	499.12	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Length without tail	11813.26	3	1	33.3	-1	9.76e-04	Mindy4b Ndufb9 Retreg2
Liver weight, left	1747.19	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Liver weight, right	19.08	3	1	33.3	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Parametrial fat weight	181.56	1	1	33.3	0	1.00e+00	Retreg2
Retroperitoneal fat weight	1315.62	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Intraocular pressure	3466.09	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Extensor digitorum longus weight	540.26	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Soleus weight	12.63	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Tibialis anterior weight	1158.38	1	1	33.3	0	1.00e+00	Retreg2
Tibia length	385.43	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Number of licking bursts	33719.1	1	1	33.3	0	1.00e+00	Retreg2
Food consumed during 24 hour testing period	17758.05	1	1	33.3	0	1.00e+00	Retreg2
Times rat made contact with spout	41.61	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Mean time between licks in bursts	37213.79	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Mean num. licks in bursts	28381.96	1	1	33.3	0	1.00e+00	Retreg2
Std. dev. time between licks in bursts	29750.31	1	1	33.3	0	1.00e+00	Retreg2
Water consumed over 24 hours	17088.15	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging indifference point 0 sec	39171.5	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging indifference point AUC	16718.88	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Indifference point function ln k	18570.82	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Indifference point function log k	18570.82	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 0 sec	41947.04	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging total patch changes 12 sec	1174.88	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 18 sec	20233.2	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Patch foraging total patch changes 24 sec	18726.81	3	2	66.7	1	2.02e-03	Mindy4b Ndufb9 Retreg2
Patch foraging total patch changes 6 sec	2604.03	3	2	66.7	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Patch foraging time to switch 0 sec	22175.26	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 0 sec	20149.67	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 12 sec	35328.83	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging water rate 18 sec	11246.17	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Patch foraging water rate 24 sec	1033.47	1	1	33.3	0	1.00e+00	Retreg2
Patch foraging water rate 6 sec	435.09	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Locomotor activity	4.13	1	0	0	0	1.00e+00	Ndufb9
Locomotor testing distance	9230.7	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Locomotor testing rearing	15859.11	3	1	33.3	-1	3.60e-04	Mindy4b Ndufb9 Retreg2
Light reinforcement 1	22112.53	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Light reinforcement 2	9190.06	3	1	33.3	-1	1.02e-03	Mindy4b Ndufb9 Retreg2
Reaction time number correct	21167.41	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Reaction time mean minus median	39993.16	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Reaction time mean minus median AUC	41343.87	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Reaction time num false alarms	15357.42	1	1	33.3	0	1.00e+00	Retreg2
Reaction time num false alarms AUC	17511.01	1	1	33.3	0	1.00e+00	Retreg2
Reaction time trials correct on left	21167.41	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Reaction time trials on left	20304.09	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Reaction time mean	9922.47	2	2	66.7	0	1.00e+00	Mindy4b Retreg2
Reaction time mean AUC	12936.48	2	2	66.7	0	1.00e+00	Mindy4b Retreg2
Median of all reaction times	2647.07	2	2	66.7	0	1.00e+00	Mindy4b Retreg2
Reaction time omissions	2795.93	3	1	33.3	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Reaction time false alarm rate	108.16	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Reaction time premature initiation rate	4871.37	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Reaction time premature initiations	17919.9	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Std. dev. reaction times	15223.97	3	1	33.3	1	3.34e-04	Mindy4b Ndufb9 Retreg2
Reaction time trials completed	20304.09	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Reaction time trials AUC	20718.6	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Social response proportion	4394.41	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Social responses	635.8	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Social time	11650.06	1	1	33.3	0	1.00e+00	Retreg2
Conditioned locomotion	1400.08	1	1	33.3	0	1.00e+00	Retreg2
Cocaine response after cond. corrected	9573.48	1	1	33.3	0	1.00e+00	Retreg2
Cocaine response after cond. not corrected	9294.65	1	1	33.3	0	1.00e+00	Retreg2
Cocaine response before conditioning	655.41	1	1	33.3	0	1.00e+00	Retreg2
Saline control response	1582.75	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. active minus inactive responses	14521.56	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. active-inactive response ratio	9575.62	3	1	33.3	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Condit. Reinf. active responses	2302.04	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. inactive responses	5447.51	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Condit. Reinf. lever presses	1935.17	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. lever reinforcers received	469.54	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	2531.81	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry latency	13282.18	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. change in total contacts	13274.44	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. index score	12744.53	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	16150.81	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	5331.08	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. magazine entry number	4012.39	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	17498.16	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever-magazine prob. diff.	11800.43	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	1164.95	1	1	33.3	0	1.00e+00	Retreg2
Conditioned reinforcement - actives	25215.11	3	2	66.7	1	1.21e-05	Mindy4b Ndufb9 Retreg2
Conditioned reinforcement - inactives	21642.11	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Conditioned locomotion	3477.64	3	3	100	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Intermittent access intake day 1-15 change	42634.93	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Intermittent access intake escalation	42032.62	2	2	66.7	0	1.00e+00	Mindy4b Retreg2
Intermittent access intake escalation 2	18090.71	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Intermitt. access day 1 inactive lever presses	60216.77	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Intermitt. access day 15 inactive lever presses	41255.98	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Intermitt. access escalation Index	23333.36	3	1	33.3	-1	3.95e-04	Mindy4b Ndufb9 Retreg2
Intermittent access day 1 total infusions	22046.89	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Intermittent access day 15 total infusions	24368.74	1	1	33.3	0	1.00e+00	Retreg2
Intermittent access terminal intake (last 3 days)	24800.59	1	1	33.3	0	1.00e+00	Retreg2
Intermittent access total infusions	181.04	1	1	33.3	0	1.00e+00	Retreg2
Intermittent access day 1 locomotion	11662.04	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Intermittent access day 15 total locomotion	42779.17	1	1	33.3	0	1.00e+00	Retreg2
Intermittent access total locomotion	47.46	3	1	33.3	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Intermittent access standard deviation	56990.22	1	1	33.3	0	1.00e+00	Retreg2
Cocaine induced anxiety	23066.22	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Post-drug Anxiety	2390.18	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Baseline Anxiety	11237.13	3	2	66.7	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Lifetime Intake	1655.49	1	1	33.3	0	1.00e+00	Retreg2
Incentive Sensitization - Responses	17856.96	3	3	100	-1	1.69e-03	Mindy4b Ndufb9 Retreg2
Incentive Sensitization - Breakpoint	13834.98	3	3	100	-1	1.79e-03	Mindy4b Ndufb9 Retreg2
Progressive ratio test 1 active lever presses	10666.73	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 1 breakpoint	10105.31	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 1 inactive lever presses	20749.71	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Progressive ratio test 2 active lever presses	3821.38	3	1	33.3	-1	1.96e-03	Mindy4b Ndufb9 Retreg2
Progressive ratio test 2 breakpoint	2853.1	3	1	33.3	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Progressive ratio test 2 inactive lever presses	24174.12	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Total sessions with >9 infusions	988.9	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Short access day 1 total inactive lever presses	9866.63	3	3	100	-1	7.87e-04	Mindy4b Ndufb9 Retreg2
Short access day 10 total inactive lever presses	69435.55	1	1	33.3	0	1.00e+00	Retreg2
Short access day 1 total infusions	19195.67	1	1	33.3	0	1.00e+00	Retreg2
Short access day 10 total infusions	7575.13	3	2	66.7	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Short access total infusions	4396.25	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Short access day 1 locomotion	12422.14	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Short access day 10 total locomotion	29411.03	2	2	66.7	0	1.00e+00	Mindy4b Retreg2
Short access total locomotion	6236.8	3	2	66.7	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Compulsive drug intake	4676.16	3	1	33.3	-1	4.65e-04	Mindy4b Ndufb9 Retreg2
One hour access (0.3 mA shock)	783.36	3	1	33.3	0	1.00e+00	Mindy4b Ndufb9 Retreg2
One hour access (shock baseline)	27499.57	1	1	33.3	0	1.00e+00	Retreg2
Number of responses in last shaping day	4546.05	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Context. condit. distance diff. score	212.47	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, session 1	1769.63	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Locomotion distance, session 1	1024.77	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, session 2	1082.02	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Locomotion distance, session 2	508.11	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, session 3	507.49	1	1	33.3	0	1.00e+00	Retreg2
Locomotion distance, session 3	4009.46	1	1	33.3	0	1.00e+00	Retreg2
Stereotopy head waving bouts, day 3	1361.96	1	1	33.3	0	1.00e+00	Retreg2
Stereotopy head waving duration, day 3	2872.44	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, session 7	292.79	1	1	33.3	0	1.00e+00	Retreg2
Locomotion distance, session 7	435.3	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving bouts, day 7	1279.33	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Stereotopy head waving duration, day 7	1081.37	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Locomotion velocity, session 8	409.23	1	1	33.3	0	1.00e+00	Retreg2
Locomotion distance, session 8	147.88	1	1	33.3	0	1.00e+00	Retreg2
Degree of sensitization distance	3670.85	1	1	33.3	0	1.00e+00	Retreg2
Degree of sensitization stereotypy	1029.63	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Condit. Reinf. active minus inactive responses	484.11	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Condit. Reinf. active-inactive response ratio	126.1	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Condit. Reinf. active responses	1386.69	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Condit. Reinf. inactive responses	2347.53	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Incentive salience index mean	3540.72	1	1	33.3	0	1.00e+00	Retreg2
Condit. Reinf. lever presses	5282.33	1	1	33.3	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 1	5589.03	1	1	33.3	0	1.00e+00	Retreg2
Time in novel zone, hab. session 1	9232.79	1	1	33.3	0	1.00e+00	Retreg2
Total zone transitions, hab. session 1	221.7	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 1	394.1	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 1	266.96	1	1	33.3	0	1.00e+00	Retreg2
Time in familiar zone, hab. session 2	5880.03	1	1	33.3	0	1.00e+00	Retreg2
Time in novel zone, hab. session 2	3159.16	1	1	33.3	0	1.00e+00	Retreg2
Total zone transitions, hab. session 2	35.66	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, hab. session 2	22.17	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, hab. session 2	31.27	1	1	33.3	0	1.00e+00	Retreg2
Novel to familiar place preference ratio	15339.58	1	1	33.3	0	1.00e+00	Retreg2
Novelty place preference	14927.56	1	1	33.3	0	1.00e+00	Retreg2
Time in novel zone, NPP test	10685.62	1	1	33.3	0	1.00e+00	Retreg2
Total zone transitions, NPP test	980.79	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Total locomotion distance, NPP test	1687.31	1	1	33.3	0	1.00e+00	Retreg2
Locomotion velocity, NPP test	953.07	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever latency	248.61	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. change in total contacts	1037.76	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. index score	384.43	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. latency score	404.63	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. lever contacts	344.19	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. magazine entry number	491.61	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. intertrial magazine entries	69.21	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Pavlov. Cond. lever-magazine prob. diff.	418.89	1	1	33.3	0	1.00e+00	Retreg2
Pavlov. Cond. response bias	583.93	1	1	33.3	0	1.00e+00	Retreg2
Bone: apparent density	2735.95	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Bone surface	6197.68	1	1	33.3	0	1.00e+00	Retreg2
Bone volume	8624.75	1	1	33.3	0	1.00e+00	Retreg2
Bone: connectivity density	841.82	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical apparent density	6014.36	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical area	2293.91	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	221.79	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical porosity	560.57	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical thickness	128.8	3	1	33.3	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Bone: cortical thickness	1464.97	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Bone: cortical tissue density	6505.97	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Bone: elastic displacement	3805.7	1	1	33.3	0	1.00e+00	Retreg2
Bone: elastic work	361.86	1	1	33.3	0	1.00e+00	Retreg2
Bone: endosteal estimation	2974.46	3	1	33.3	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Bone: endosteal perimeter	11863.6	1	1	33.3	0	1.00e+00	Retreg2
Bone: final force	1600.36	1	1	33.3	0	1.00e+00	Retreg2
Bone: final moment	219.15	1	1	33.3	0	1.00e+00	Retreg2
Bone: marrow area	4718.77	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum diameter	3037.24	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Bone: maximum force	8697.09	1	1	33.3	0	1.00e+00	Retreg2
Bone: maximum moment	2996.54	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Bone: minimum diameter	4100.86	1	1	33.3	0	1.00e+00	Retreg2
Bone: periosteal estimation	9791.57	1	1	33.3	0	1.00e+00	Retreg2
Bone: periosteal perimeter	11400.25	1	1	33.3	0	1.00e+00	Retreg2
Bone: post-yield work	6839.22	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Bone: stiffness	9032.86	1	1	33.3	0	1.00e+00	Retreg2
Bone: tissue strength	2995.95	1	1	33.3	0	1.00e+00	Retreg2
Bone: trabecular number	5387.39	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular spacing	3988.39	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Bone: trabecular thickness	8476.26	1	1	33.3	0	1.00e+00	Retreg2
Bone: trabecular tissue density	7288.68	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
LgA early post infusion interval	17802.46	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
LgA late post infusion interval	17475.91	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
LgA early loading	27294.21	3	1	33.3	1	4.96e-05	Mindy4b Ndufb9 Retreg2
LgA early average infusions	9744.22	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
LgA late average infusions	21037.5	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
LgA early timeout	12057.77	1	1	33.3	0	1.00e+00	Retreg2
LgA late timeout	14718.76	3	1	33.3	-1	1.07e-03	Mindy4b Ndufb9 Retreg2
LgA early titration	20832.48	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
LgA late titration	16928.18	3	2	66.7	1	2.63e-04	Mindy4b Ndufb9 Retreg2
LgA total infusion	10156.14	3	2	66.7	1	7.53e-05	Mindy4b Ndufb9 Retreg2
LgA PC1 addiction-like behavior	26298.24	3	2	66.7	1	1.31e-05	Mindy4b Ndufb9 Retreg2
ShA PR total presses	7485.8	3	2	66.7	0	1.00e+00	Mindy4b Ndufb9 Retreg2
LgA PR total presses	3284.62	2	2	66.7	0	1.00e+00	Mindy4b Retreg2
ShA early post infusion interval	8072.47	1	1	33.3	0	1.00e+00	Retreg2
ShA late post infusion interval	160.61	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
ShA early loading	91.9	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
ShA late loading	14195.7	3	1	33.3	1	2.16e-05	Mindy4b Ndufb9 Retreg2
ShA early average infusions	9734.11	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
ShA late average infusions	2967.47	3	1	33.3	0	1.00e+00	Mindy4b Ndufb9 Retreg2
ShA early timeout	267.78	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
ShA late timeout	18424.65	1	1	33.3	0	1.00e+00	Retreg2
ShA early titration	734.14	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
ShA late titration	3832.49	3	2	66.7	0	1.00e+00	Mindy4b Ndufb9 Retreg2
ShA total infusions	9326.33	3	1	33.3	1	2.29e-05	Mindy4b Ndufb9 Retreg2
Shock compulsivity	58896.87	1	1	33.3	0	1.00e+00	Retreg2
Total infusions	7202.46	3	2	66.7	1	3.70e-04	Mindy4b Ndufb9 Retreg2
Breakpoint value in progressive ratio session	18806.07	1	1	33.3	0	1.00e+00	Retreg2
Distance traveled before self-admin	16851.09	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Distance traveled after self-admin	32464.08	1	1	33.3	0	1.00e+00	Retreg2
Delta time in closed arm before/after self-admin	126.6	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Delta time in open arm before/after self-admin	7571.82	1	1	33.3	0	1.00e+00	Retreg2
Diff in mean of infusions in LGA sessions	12222.37	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Extinction: sum of active levers before priming	9473.6	3	2	66.7	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Active lever presses in extinction session 6	738.98	1	1	33.3	0	1.00e+00	Retreg2
Delta distance traveled before/after self-admin	992.91	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Delta ambulatory time before/after self-admin	10292.75	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Time in closed arm before self-admin	26866.11	1	1	33.3	0	1.00e+00	Retreg2
Time in closed arm after self-admin	4591.18	1	1	33.3	0	1.00e+00	Retreg2
Time in open arm before self-admin	2207.41	3	2	66.7	-1	3.57e-03	Mindy4b Ndufb9 Retreg2
Time in open arm after self-admin	261.21	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Sum of active levers in priming session hrs 5-6	496.26	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Time to tail flick, vehicle, before self-admin	4460.73	3	1	33.3	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Time to tail flick, vehicle, after self-admin	10549.62	3	1	33.3	1	4.98e-04	Mindy4b Ndufb9 Retreg2
Time to tail flick, test, before self-admin	4093.6	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Time to tail flick, test, after self-admin	504.65	3	3	100	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Delta time to tail flick, vehicle, before/after SA	3276.94	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Delta time to tail flick, test, before/after SA	5241.49	3	2	66.7	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Ambulatory time before self-admin	39445.39	1	1	33.3	0	1.00e+00	Retreg2
Ambulatory time after self-admin	26614.91	1	1	33.3	0	1.00e+00	Retreg2
Total heroin consumption	240.55	1	1	33.3	0	1.00e+00	Retreg2
Area under the delay curve	8270.15	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Delay disc. indifference point, 0s delay	1084.93	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Delay disc. indifference point, 16s delay	10984.61	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Delay disc. indifference point, 2s delay	83.07	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Delay disc. indifference point, 24s delay	32437.06	1	1	33.3	0	1.00e+00	Retreg2
Delay disc. indifference point, 4s delay	216.13	3	1	33.3	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Delay disc. indifference point, 8s delay	16687.74	1	1	33.3	0	1.00e+00	Retreg2
Delay discount exponential model param	5646.35	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Delay discount hyperbolic model param	4099.4	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Fecal boli incidents, locomotor time 1	30605.7	1	1	33.3	0	1.00e+00	Retreg2
Change in fecal boli incidents, locomotor task	1904.41	3	2	66.7	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Time >=10cm from walls, locomotor time 1	3262.13	3	1	33.3	-1	3.89e-04	Mindy4b Ndufb9 Retreg2
Bouts of movement, locomotor time 1	5395.51	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Total resting periods, locomotor time 1	2793.59	1	1	33.3	0	1.00e+00	Retreg2
Rest time, locomotor task time 1	11183.83	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Distance moved, locomotor task time 1	22966.92	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Vertical activity count, locomotor time 1	71190.42	1	1	33.3	0	1.00e+00	Retreg2
Time >=10cm from walls, locomotor time 2	23732.72	2	2	66.7	0	1.00e+00	Mindy4b Retreg2
Bouts of movement, locomotor time 2	27352.16	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Total resting periods, locomotor time 2	33022.29	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Rest time, locomotor task time 2	8506.4	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Distance moved, locomotor task time 2	2832.29	3	1	33.3	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Vertical activity count, locomotor time 2	17861.61	2	2	66.7	0	1.00e+00	Mindy4b Retreg2
Weight adjusted by age	23613.39	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, delayed vs. immediate footshock	6730.03	2	1	33.3	0	1.00e+00	Mindy4b Retreg2
Locomotion in novel chamber	1993.33	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Locomotion in novel chamber post-restriction	16360.96	3	1	33.3	-1	5.42e-05	Mindy4b Ndufb9 Retreg2
Progressive ratio	16986.21	3	2	66.7	-1	1.16e-04	Mindy4b Ndufb9 Retreg2
Food seeking constrained by brief footshock	941.83	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Seeking ratio, punishment vs. effort	20653.58	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Run reversals in cocaine runway, females	9406.04	1	1	33.3	0	1.00e+00	Retreg2
Run reversals in cocaine runway, males	2591.99	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Latency to leave start box in cocaine runway	16290.75	1	1	33.3	0	1.00e+00	Retreg2
Latency to leave start box in cocaine runway, F	2400.69	3	2	66.7	0	1.00e+00	Mindy4b Ndufb9 Retreg2
Latency to leave start box in cocaine runway, M	867.32	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Co content in liver	1133.25	1	1	33.3	0	1.00e+00	Retreg2
Cu content in liver	28.08	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Fe content in liver	1344.53	1	1	33.3	0	1.00e+00	Retreg2
K content in liver	1519.62	1	1	33.3	0	1.00e+00	Retreg2
Mg content in liver	6026.97	1	1	33.3	0	1.00e+00	Retreg2
Mn content in liver	537.3	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Na content in liver	2013.84	2	1	33.3	0	1.00e+00	Ndufb9 Retreg2
Rb content in liver	71.08	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2
Se content in liver	8.63	1	0	0	0	1.00e+00	Ndufb9
Zn content in liver	1887.46	2	2	66.7	0	1.00e+00	Ndufb9 Retreg2

Associations by panel

Tissue	RNA modality	# hits	% hits/tests	Avg chisq
Adipose	alternative polyA	0	0	1.12
Adipose	alternative TSS	0	0	1.02
Adipose	gene expression	0	0	1.08
Adipose	isoform ratio	0	0	1.06
Adipose	intron excision ratio	0	0	1.06
Adipose	mRNA stability	1	0	1.13
BLA	alternative polyA	0	0	1.06
BLA	alternative TSS	0	0	1.06
BLA	gene expression	0	0	1.06
BLA	isoform ratio	0	0	1.04
BLA	intron excision ratio	0	0	1.01
BLA	mRNA stability	0	0	1.11
Brain	alternative polyA	0	0	1.09
Brain	alternative TSS	0	0	1.09
Brain	gene expression	0	0	1.08
Brain	isoform ratio	0	0	1.11
Brain	intron excision ratio	0	0	1.05
Brain	mRNA stability	0	0	1.12
Eye	alternative polyA	0	0	1.09
Eye	alternative TSS	0	0	0.98
Eye	gene expression	0	0	1.05
Eye	isoform ratio	0	0	1.12
Eye	intron excision ratio	0	0	1.04
Eye	mRNA stability	0	0	1.12
IC	alternative polyA	0	0	1.17
IC	alternative TSS	0	0	1.09
IC	gene expression	0	0	1.06
IC	isoform ratio	0	0	1.09
IC	intron excision ratio	0	0	1.04
IC	mRNA stability	0	0	1.11
IL	alternative polyA	0	0	1.08
IL	alternative TSS	0	0	1.02
IL	gene expression	0	0	1.07
IL	isoform ratio	0	0	1.05
IL	intron excision ratio	0	0	0.97
IL	mRNA stability	0	0	1.15
LHb	alternative polyA	0	0	1.05
LHb	alternative TSS	0	0	1.14
LHb	gene expression	0	0	1.06
LHb	isoform ratio	0	0	1.12
LHb	intron excision ratio	0	0	1.04
LHb	mRNA stability	0	0	1.12
Liver	alternative polyA	0	0	1.13
Liver	alternative TSS	0	0	1.05
Liver	gene expression	0	0	1.08
Liver	isoform ratio	0	0	1.08
Liver	intron excision ratio	0	0	0.99
Liver	mRNA stability	0	0	1.04
NAcc	alternative polyA	2	0.1	94.33
NAcc	alternative TSS	0	0	1.11
NAcc	gene expression	0	0	1.07
NAcc	isoform ratio	0	0	1.1
NAcc	intron excision ratio	1	0	1.06
NAcc	mRNA stability	0	0	1.1
OFC	alternative polyA	0	0	1.09
OFC	alternative TSS	0	0	0.97
OFC	gene expression	0	0	1.03
OFC	isoform ratio	0	0	1.09
OFC	intron excision ratio	0	0	1.07
OFC	mRNA stability	0	0	1.15
PL	alternative polyA	0	0	1.11
PL	alternative TSS	0	0	1.09
PL	gene expression	0	0	1.07
PL	isoform ratio	0	0	1.07
PL	intron excision ratio	0	0	1.06
PL	mRNA stability	0	0	1.12
pVTA	alternative polyA	0	0	1.18
pVTA	alternative TSS	0	0	1.13
pVTA	gene expression	0	0	1.06
pVTA	isoform ratio	0	0	1.14
pVTA	intron excision ratio	0	0	1.03
pVTA	mRNA stability	0	0	1.11
RMTg	alternative polyA	0	0	0.97
RMTg	alternative TSS	0	0	1.12
RMTg	gene expression	0	0	1.01
RMTg	isoform ratio	0	0	1.09
RMTg	intron excision ratio	0	0	1.01
RMTg	mRNA stability	0	0	1.1