LgA PR total presses

The max value of active lever presses across pr 02 and pr 03

Tags: Behavior · Cocaine

Project: u01_olivier_george_cocaine

4 loci · 4 genes with independent associations · 4 total associated genes

Significant Loci

# Chr Start pos End pos # assoc genes # joint models Best TWAS P Best GWAS P Cond GWAS P Joint genes
1 chr2 144511896 145907690 1 1 2.61e-19 4.97e-04 1.00e+00 Mindy4b
2 chr5 118282290 119677504 1 1 4.26e-09 2.20e-01 1.00e+00 Atg4c
3 chr9 83390749 84777604 1 1 0.00e+00 3.82e-01 1.00e+00 Retreg2
4 chr17 61510864 62906219 1 1 1.18e-17 1.17e-01 3.65e-03 Ccny

Pleiotropic Associations

Trait Chi2 ratio # genes+ # genes++ % genes++ Corr Corr P Genes
BMI with tail 439.12 2 2 50 0 1.00e+00 Mindy4b Retreg2
BMI without tail 19084.44 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
Body weight 5.14 2 1 25 0 1.00e+00 Mindy4b Retreg2
Epididymis fat weight 18145.77 2 2 50 0 1.00e+00 Ccny Retreg2
Glucose 277.03 2 1 25 0 1.00e+00 Atg4c Retreg2
Heart weight 3065.65 1 1 25 0 1.00e+00 Retreg2
Left kidney weight 18350.36 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
Right kidney weight 20203.59 2 2 50 0 1.00e+00 Ccny Retreg2
Tail length 28919.24 1 1 25 0 1.00e+00 Retreg2
Length with tail 1484.46 1 1 25 0 1.00e+00 Retreg2
Length without tail 15748.52 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
Liver weight, left 1746.03 2 1 25 0 1.00e+00 Ccny Retreg2
Liver weight, right 25.94 2 1 25 0 1.00e+00 Mindy4b Retreg2
Parametrial fat weight 181.56 1 1 25 0 1.00e+00 Retreg2
Retroperitoneal fat weight 1316.13 3 2 50 0 1.00e+00 Atg4c Mindy4b Retreg2
Intraocular pressure 10386.52 1 1 25 0 1.00e+00 Retreg2
Extensor digitorum longus weight 540.26 2 1 25 0 1.00e+00 Mindy4b Retreg2
Soleus weight 20.71 1 1 25 0 1.00e+00 Retreg2
Tibialis anterior weight 1158.38 1 1 25 0 1.00e+00 Retreg2
Tibia length 767.35 1 1 25 0 1.00e+00 Retreg2
Number of licking bursts 67424.86 1 1 25 0 1.00e+00 Retreg2
Food consumed during 24 hour testing period 11841.04 3 1 25 0 1.00e+00 Atg4c Ccny Retreg2
Times rat made contact with spout 71.66 1 1 25 0 1.00e+00 Retreg2
Mean time between licks in bursts 111630.35 1 1 25 0 1.00e+00 Retreg2
Mean num. licks in bursts 56750.08 1 1 25 0 1.00e+00 Retreg2
Std. dev. time between licks in bursts 29750.31 1 1 25 0 1.00e+00 Retreg2
Water consumed over 24 hours 17087.99 2 1 25 0 1.00e+00 Ccny Retreg2
Patch foraging indifference point 0 sec 19587.91 2 1 25 0 1.00e+00 Atg4c Retreg2
Patch foraging indifference point AUC 25074.08 2 2 50 0 1.00e+00 Ccny Retreg2
Indifference point function ln k 27833.74 2 2 50 0 1.00e+00 Ccny Retreg2
Indifference point function log k 27833.74 2 2 50 0 1.00e+00 Ccny Retreg2
Patch foraging total patch changes 0 sec 20976.22 2 1 25 0 1.00e+00 Atg4c Retreg2
Patch foraging total patch changes 12 sec 785.46 3 2 50 0 1.00e+00 Atg4c Ccny Retreg2
Patch foraging total patch changes 18 sec 13488.06 3 1 25 0 1.00e+00 Atg4c Ccny Retreg2
Patch foraging total patch changes 24 sec 24937.78 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
Patch foraging total patch changes 6 sec 1954.26 4 1 25 -0.99 1.04e-02 Atg4c Ccny Mindy4b Retreg2
Patch foraging time to switch 0 sec 66489.31 1 1 25 0 1.00e+00 Retreg2
Patch foraging water rate 0 sec 60426.37 1 1 25 0 1.00e+00 Retreg2
Patch foraging water rate 12 sec 35330.95 2 2 50 0 1.00e+00 Ccny Retreg2
Patch foraging water rate 18 sec 33728.57 1 1 25 0 1.00e+00 Retreg2
Patch foraging water rate 24 sec 1033.47 1 1 25 0 1.00e+00 Retreg2
Patch foraging water rate 6 sec 288.46 3 2 50 0 1.00e+00 Atg4c Ccny Retreg2
Locomotor activity 17.21 1 0 0 0 1.00e+00 Ccny
Locomotor testing distance 13846.55 2 2 50 0 1.00e+00 Ccny Retreg2
Locomotor testing rearing 31700.47 2 1 25 0 1.00e+00 Mindy4b Retreg2
Light reinforcement 1 16588.41 4 2 50 0.99 1.28e-02 Atg4c Ccny Mindy4b Retreg2
Light reinforcement 2 12261.92 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
Reaction time number correct 31739.87 2 1 25 0 1.00e+00 Ccny Retreg2
Reaction time mean minus median 119950.29 1 1 25 0 1.00e+00 Retreg2
Reaction time mean minus median AUC 123988.85 1 1 25 0 1.00e+00 Retreg2
Reaction time num false alarms 15357.42 1 1 25 0 1.00e+00 Retreg2
Reaction time num false alarms AUC 17510.62 2 1 25 0 1.00e+00 Ccny Retreg2
Reaction time trials correct on left 31739.87 2 1 25 0 1.00e+00 Ccny Retreg2
Reaction time trials on left 30447.09 2 1 25 0 1.00e+00 Ccny Retreg2
Reaction time mean 9919.69 3 2 50 0 1.00e+00 Atg4c Mindy4b Retreg2
Reaction time mean AUC 12933.07 3 2 50 0 1.00e+00 Atg4c Mindy4b Retreg2
Median of all reaction times 2646.1 3 2 50 0 1.00e+00 Atg4c Mindy4b Retreg2
Reaction time omissions 4190.27 2 1 25 0 1.00e+00 Mindy4b Retreg2
Reaction time false alarm rate 210.6 1 1 25 0 1.00e+00 Retreg2
Reaction time premature initiation rate 4871.37 2 1 25 0 1.00e+00 Mindy4b Retreg2
Reaction time premature initiations 26874.85 2 1 25 0 1.00e+00 Mindy4b Retreg2
Std. dev. reaction times 20291.99 3 1 25 0 1.00e+00 Atg4c Mindy4b Retreg2
Reaction time trials completed 30447.09 2 1 25 0 1.00e+00 Ccny Retreg2
Reaction time trials AUC 31070.91 2 1 25 0 1.00e+00 Ccny Retreg2
Social response proportion 2935.42 3 1 25 0 1.00e+00 Atg4c Mindy4b Retreg2
Social responses 635.36 2 1 25 0 1.00e+00 Ccny Retreg2
Social time 11650.06 1 1 25 0 1.00e+00 Retreg2
Conditioned locomotion 1400.08 1 1 25 0 1.00e+00 Retreg2
Cocaine response after cond. corrected 9569.48 2 1 25 0 1.00e+00 Atg4c Retreg2
Cocaine response after cond. not corrected 9290.03 2 1 25 0 1.00e+00 Atg4c Retreg2
Cocaine response before conditioning 655.41 1 1 25 0 1.00e+00 Retreg2
Saline control response 3160.68 1 1 25 0 1.00e+00 Retreg2
Condit. Reinf. active minus inactive responses 14521.56 1 1 25 0 1.00e+00 Retreg2
Condit. Reinf. active-inactive response ratio 14359.76 2 1 25 0 1.00e+00 Mindy4b Retreg2
Condit. Reinf. active responses 2302.04 1 1 25 0 1.00e+00 Retreg2
Condit. Reinf. inactive responses 5447.51 2 1 25 0 1.00e+00 Mindy4b Retreg2
Condit. Reinf. lever presses 3863.86 1 1 25 0 1.00e+00 Retreg2
Condit. Reinf. lever reinforcers received 469.54 1 1 25 0 1.00e+00 Retreg2
Pavlov. Cond. lever latency 2531.81 1 1 25 0 1.00e+00 Retreg2
Pavlov. Cond. magazine entry latency 6643.71 2 1 25 0 1.00e+00 Atg4c Retreg2
Pavlov. Cond. change in total contacts 39811.91 1 1 25 0 1.00e+00 Retreg2
Pavlov. Cond. index score 12744.53 1 1 25 0 1.00e+00 Retreg2
Pavlov. Cond. latency score 16150.81 1 1 25 0 1.00e+00 Retreg2
Pavlov. Cond. lever contacts 5331.08 1 1 25 0 1.00e+00 Retreg2
Pavlov. Cond. magazine entry number 2009.54 2 1 25 0 1.00e+00 Atg4c Retreg2
Pavlov. Cond. intertrial magazine entries 34989.79 1 1 25 0 1.00e+00 Retreg2
Pavlov. Cond. lever-magazine prob. diff. 11800.43 1 1 25 0 1.00e+00 Retreg2
Pavlov. Cond. response bias 1164.95 1 1 25 0 1.00e+00 Retreg2
Conditioned reinforcement - actives 33603.11 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
Conditioned reinforcement - inactives 21630.51 3 1 25 0 1.00e+00 Atg4c Ccny Retreg2
Conditioned locomotion 3459.31 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
Intermittent access intake day 1-15 change 31974.39 4 1 25 -0.98 1.53e-02 Atg4c Ccny Mindy4b Retreg2
Intermittent access intake escalation 42029.41 3 2 50 0 1.00e+00 Atg4c Mindy4b Retreg2
Intermittent access intake escalation 2 12070.75 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
Intermitt. access day 1 inactive lever presses 90308.51 2 1 25 0 1.00e+00 Ccny Retreg2
Intermitt. access day 15 inactive lever presses 123608.2 1 1 25 0 1.00e+00 Retreg2
Intermitt. access escalation Index 46656.07 2 1 25 0 1.00e+00 Mindy4b Retreg2
Intermittent access day 1 total infusions 22045.38 3 1 25 0 1.00e+00 Atg4c Mindy4b Retreg2
Intermittent access day 15 total infusions 48731.91 1 1 25 0 1.00e+00 Retreg2
Intermittent access terminal intake (last 3 days) 24800.59 1 1 25 0 1.00e+00 Retreg2
Intermittent access total infusions 93.49 2 1 25 0 1.00e+00 Ccny Retreg2
Intermittent access day 1 locomotion 11662.75 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
Intermittent access day 15 total locomotion 28525.66 3 2 50 0 1.00e+00 Atg4c Ccny Retreg2
Intermittent access total locomotion 65.32 2 1 25 0 1.00e+00 Mindy4b Retreg2
Intermittent access standard deviation 56992.22 2 2 50 0 1.00e+00 Ccny Retreg2
Cocaine induced anxiety 34553.78 2 1 25 0 1.00e+00 Ccny Retreg2
Post-drug Anxiety 4753.56 1 1 25 0 1.00e+00 Retreg2
Baseline Anxiety 11177.88 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
Lifetime Intake 834.23 2 1 25 0 1.00e+00 Ccny Retreg2
Incentive Sensitization - Responses 17849.29 4 3 75 0.98 1.53e-02 Atg4c Ccny Mindy4b Retreg2
Incentive Sensitization - Breakpoint 13832.49 4 3 75 0.98 1.51e-02 Atg4c Ccny Mindy4b Retreg2
Progressive ratio test 1 active lever presses 16000.1 2 1 25 0 1.00e+00 Ccny Retreg2
Progressive ratio test 1 breakpoint 15155.7 2 1 25 0 1.00e+00 Ccny Retreg2
Progressive ratio test 1 inactive lever presses 31108.97 2 1 25 0 1.00e+00 Atg4c Retreg2
Progressive ratio test 2 active lever presses 3824.24 4 1 25 0.99 1.18e-02 Atg4c Ccny Mindy4b Retreg2
Progressive ratio test 2 breakpoint 2146.17 4 1 25 0.99 1.01e-02 Atg4c Ccny Mindy4b Retreg2
Progressive ratio test 2 inactive lever presses 36255.27 2 1 25 0 1.00e+00 Ccny Retreg2
Total sessions with >9 infusions 502.7 4 2 50 1 5.93e-05 Atg4c Ccny Mindy4b Retreg2
Short access day 1 total inactive lever presses 13146.2 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
Short access day 10 total inactive lever presses 69442.46 2 2 50 0 1.00e+00 Ccny Retreg2
Short access day 1 total infusions 19232.26 2 2 50 0 1.00e+00 Ccny Retreg2
Short access day 10 total infusions 7569.39 3 1 25 0 1.00e+00 Atg4c Mindy4b Retreg2
Short access total infusions 2939.89 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
Short access day 1 locomotion 12408.48 2 1 25 0 1.00e+00 Ccny Retreg2
Short access day 10 total locomotion 29406.31 3 2 50 0 1.00e+00 Atg4c Mindy4b Retreg2
Short access total locomotion 9350.94 2 2 50 0 1.00e+00 Mindy4b Retreg2
Compulsive drug intake 9343.13 2 1 25 0 1.00e+00 Mindy4b Retreg2
One hour access (0.3 mA shock) 783.95 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
One hour access (shock baseline) 54988.81 1 1 25 0 1.00e+00 Retreg2
Number of responses in last shaping day 4552.03 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
Context. condit. distance diff. score 212.47 1 1 25 0 1.00e+00 Retreg2
Locomotion velocity, session 1 3523.61 1 1 25 0 1.00e+00 Retreg2
Locomotion distance, session 1 516.6 2 1 25 0 1.00e+00 Ccny Retreg2
Locomotion velocity, session 2 724.26 3 1 25 0 1.00e+00 Atg4c Mindy4b Retreg2
Locomotion distance, session 2 258.34 2 1 25 0 1.00e+00 Ccny Retreg2
Locomotion velocity, session 3 507.49 1 1 25 0 1.00e+00 Retreg2
Locomotion distance, session 3 4009.46 1 1 25 0 1.00e+00 Retreg2
Stereotopy head waving bouts, day 3 1361.96 1 1 25 0 1.00e+00 Retreg2
Stereotopy head waving duration, day 3 2872.44 1 1 25 0 1.00e+00 Retreg2
Locomotion velocity, session 7 292.79 1 1 25 0 1.00e+00 Retreg2
Locomotion distance, session 7 856.72 1 1 25 0 1.00e+00 Retreg2
Stereotopy head waving bouts, day 7 2509.72 1 1 25 0 1.00e+00 Retreg2
Stereotopy head waving duration, day 7 2115.93 1 1 25 0 1.00e+00 Retreg2
Locomotion velocity, session 8 409.23 1 1 25 0 1.00e+00 Retreg2
Locomotion distance, session 8 147.88 1 1 25 0 1.00e+00 Retreg2
Degree of sensitization distance 3670.85 1 1 25 0 1.00e+00 Retreg2
Degree of sensitization stereotypy 2042.98 1 1 25 0 1.00e+00 Retreg2
Condit. Reinf. active minus inactive responses 327.4 3 1 25 0 1.00e+00 Atg4c Mindy4b Retreg2
Condit. Reinf. active-inactive response ratio 88.36 3 1 25 0 1.00e+00 Atg4c Mindy4b Retreg2
Condit. Reinf. active responses 929.52 3 1 25 0 1.00e+00 Atg4c Mindy4b Retreg2
Condit. Reinf. inactive responses 4681.39 1 1 25 0 1.00e+00 Retreg2
Incentive salience index mean 1776.71 2 1 25 0 1.00e+00 Atg4c Retreg2
Condit. Reinf. lever presses 5282.33 1 1 25 0 1.00e+00 Retreg2
Time in familiar zone, hab. session 1 11168.49 1 1 25 0 1.00e+00 Retreg2
Time in novel zone, hab. session 1 4621.25 2 1 25 0 1.00e+00 Atg4c Retreg2
Total zone transitions, hab. session 1 429.72 1 1 25 0 1.00e+00 Retreg2
Total locomotion distance, hab. session 1 394.1 1 1 25 0 1.00e+00 Retreg2
Locomotion velocity, hab. session 1 266.96 1 1 25 0 1.00e+00 Retreg2
Time in familiar zone, hab. session 2 5880.03 1 1 25 0 1.00e+00 Retreg2
Time in novel zone, hab. session 2 3159.43 2 1 25 0 1.00e+00 Atg4c Retreg2
Total zone transitions, hab. session 2 63.93 1 1 25 0 1.00e+00 Retreg2
Total locomotion distance, hab. session 2 22.17 1 1 25 0 1.00e+00 Retreg2
Locomotion velocity, hab. session 2 31.27 1 1 25 0 1.00e+00 Retreg2
Novel to familiar place preference ratio 5118.17 3 1 25 0 1.00e+00 Atg4c Ccny Retreg2
Novelty place preference 7469.82 2 1 25 0 1.00e+00 Atg4c Retreg2
Time in novel zone, NPP test 5350.38 2 1 25 0 1.00e+00 Atg4c Retreg2
Total zone transitions, NPP test 1935.62 1 1 25 0 1.00e+00 Retreg2
Total locomotion distance, NPP test 1687.31 1 1 25 0 1.00e+00 Retreg2
Locomotion velocity, NPP test 479.14 2 1 25 0 1.00e+00 Ccny Retreg2
Pavlov. Cond. lever latency 249.61 2 1 25 0 1.00e+00 Atg4c Retreg2
Pavlov. Cond. change in total contacts 1037.76 1 1 25 0 1.00e+00 Retreg2
Pavlov. Cond. index score 195.36 2 1 25 0 1.00e+00 Atg4c Retreg2
Pavlov. Cond. latency score 404.63 1 1 25 0 1.00e+00 Retreg2
Pavlov. Cond. lever contacts 343.28 2 1 25 0 1.00e+00 Atg4c Retreg2
Pavlov. Cond. magazine entry number 248.32 2 1 25 0 1.00e+00 Atg4c Retreg2
Pavlov. Cond. intertrial magazine entries 123.55 1 1 25 0 1.00e+00 Retreg2
Pavlov. Cond. lever-magazine prob. diff. 212.16 2 1 25 0 1.00e+00 Atg4c Retreg2
Pavlov. Cond. response bias 296.22 2 1 25 0 1.00e+00 Atg4c Retreg2
Bone: apparent density 5461.77 1 1 25 0 1.00e+00 Retreg2
Bone surface 6197.68 1 1 25 0 1.00e+00 Retreg2
Bone volume 8624.75 1 1 25 0 1.00e+00 Retreg2
Bone: connectivity density 1667.52 1 1 25 0 1.00e+00 Retreg2
Bone: cortical apparent density 12020.36 1 1 25 0 1.00e+00 Retreg2
Bone: cortical area 4581.96 1 1 25 0 1.00e+00 Retreg2
Bone: cortical porosity 432.96 1 1 25 0 1.00e+00 Retreg2
Bone: cortical porosity 1113.18 1 1 25 0 1.00e+00 Retreg2
Bone: cortical thickness 189.28 2 1 25 0 1.00e+00 Mindy4b Retreg2
Bone: cortical thickness 2918.77 1 1 25 0 1.00e+00 Retreg2
Bone: cortical tissue density 13002.58 1 1 25 0 1.00e+00 Retreg2
Bone: elastic displacement 7604.03 1 1 25 0 1.00e+00 Retreg2
Bone: elastic work 361.86 1 1 25 0 1.00e+00 Retreg2
Bone: endosteal estimation 4458.15 2 1 25 0 1.00e+00 Mindy4b Retreg2
Bone: endosteal perimeter 11863.6 1 1 25 0 1.00e+00 Retreg2
Bone: final force 1600.36 1 1 25 0 1.00e+00 Retreg2
Bone: final moment 219.15 1 1 25 0 1.00e+00 Retreg2
Bone: marrow area 9430.07 1 1 25 0 1.00e+00 Retreg2
Bone: maximum diameter 6068.73 1 1 25 0 1.00e+00 Retreg2
Bone: maximum force 8697.09 1 1 25 0 1.00e+00 Retreg2
Bone: maximum moment 5989.29 1 1 25 0 1.00e+00 Retreg2
Bone: minimum diameter 4100.86 1 1 25 0 1.00e+00 Retreg2
Bone: periosteal estimation 9791.57 1 1 25 0 1.00e+00 Retreg2
Bone: periosteal perimeter 11400.25 1 1 25 0 1.00e+00 Retreg2
Bone: post-yield work 6839.22 2 1 25 0 1.00e+00 Mindy4b Retreg2
Bone: stiffness 9032.86 1 1 25 0 1.00e+00 Retreg2
Bone: tissue strength 2995.95 1 1 25 0 1.00e+00 Retreg2
Bone: trabecular number 10739.78 1 1 25 0 1.00e+00 Retreg2
Bone: trabecular spacing 7952.12 1 1 25 0 1.00e+00 Retreg2
Bone: trabecular thickness 8476.26 1 1 25 0 1.00e+00 Retreg2
Bone: trabecular tissue density 14554.51 1 1 25 0 1.00e+00 Retreg2
LgA early post infusion interval 26685.21 2 2 50 0 1.00e+00 Ccny Retreg2
LgA late post infusion interval 17464.3 2 1 25 0 1.00e+00 Atg4c Retreg2
LgA early loading 36382.84 3 1 25 0 1.00e+00 Atg4c Mindy4b Retreg2
LgA late loading 34816.88 4 2 50 -0.98 2.09e-02 Atg4c Ccny Mindy4b Retreg2
LgA early average infusions 14615.48 2 1 25 0 1.00e+00 Ccny Retreg2
LgA late average infusions 63066.53 1 1 25 0 1.00e+00 Retreg2
LgA early timeout 6037.95 2 1 25 0 1.00e+00 Atg4c Retreg2
LgA late timeout 19619.42 3 1 25 0 1.00e+00 Atg4c Mindy4b Retreg2
LgA early titration 62424.33 1 1 25 0 1.00e+00 Retreg2
LgA late titration 33828.08 2 1 25 0 1.00e+00 Mindy4b Retreg2
LgA total infusion 13529.57 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
LgA PC1 addiction-like behavior 35041.13 3 1 25 0 1.00e+00 Atg4c Mindy4b Retreg2
ShA PR total presses 11217.09 2 2 50 0 1.00e+00 Mindy4b Retreg2
ShA early post infusion interval 8072.47 1 1 25 0 1.00e+00 Retreg2
ShA late post infusion interval 105.06 3 1 25 0 1.00e+00 Atg4c Ccny Retreg2
ShA early loading 53.78 3 1 25 0 1.00e+00 Atg4c Ccny Retreg2
ShA late loading 18920 3 1 25 0 1.00e+00 Atg4c Mindy4b Retreg2
ShA early average infusions 9738.41 2 2 50 0 1.00e+00 Ccny Retreg2
ShA late average infusions 4447.78 2 1 25 0 1.00e+00 Mindy4b Retreg2
ShA early timeout 179.49 3 1 25 0 1.00e+00 Atg4c Ccny Retreg2
ShA late timeout 18424.65 1 1 25 0 1.00e+00 Retreg2
ShA early titration 758.35 2 2 50 0 1.00e+00 Ccny Retreg2
ShA late titration 3830.46 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
ShA total infusions 18644.65 2 1 25 0 1.00e+00 Mindy4b Retreg2
Shock compulsivity 58902.44 2 2 50 0 1.00e+00 Ccny Retreg2
Total infusions 9589.19 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
Breakpoint value in progressive ratio session 37605.61 1 1 25 0 1.00e+00 Retreg2
Distance traveled before self-admin 16860.3 3 2 50 0 1.00e+00 Atg4c Ccny Retreg2
Distance traveled after self-admin 10850.49 3 3 75 0 1.00e+00 Atg4c Ccny Retreg2
Delta time in closed arm before/after self-admin 133.04 3 2 50 0 1.00e+00 Atg4c Ccny Retreg2
Delta time in open arm before/after self-admin 5052.88 3 1 25 0 1.00e+00 Atg4c Ccny Retreg2
Diff in mean of infusions in LGA sessions 18339.3 2 2 50 0 1.00e+00 Atg4c Retreg2
Extinction: sum of active levers before priming 9474.93 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
Active lever presses in extinction session 6 393.1 2 2 50 0 1.00e+00 Ccny Retreg2
Delta distance traveled before/after self-admin 1480.05 2 1 25 0 1.00e+00 Ccny Retreg2
Delta ambulatory time before/after self-admin 10288.69 3 1 25 0 1.00e+00 Atg4c Ccny Retreg2
Time in closed arm before self-admin 8961.26 3 1 25 0 1.00e+00 Atg4c Ccny Retreg2
Time in closed arm after self-admin 2325.44 2 2 50 0 1.00e+00 Ccny Retreg2
Time in open arm before self-admin 2200.43 4 2 50 0.96 3.73e-02 Atg4c Ccny Mindy4b Retreg2
Time in open arm after self-admin 243.22 2 1 25 0 1.00e+00 Ccny Retreg2
Sum of active levers in priming session hrs 5-6 978.69 1 1 25 0 1.00e+00 Retreg2
Time to tail flick, vehicle, before self-admin 4491.03 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
Time to tail flick, vehicle, after self-admin 14054.93 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
Time to tail flick, test, before self-admin 4075.27 2 1 25 0 1.00e+00 Atg4c Retreg2
Time to tail flick, test, after self-admin 485.93 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
Delta time to tail flick, vehicle, before/after SA 3295.18 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
Delta time to tail flick, test, before/after SA 7855.87 2 2 50 0 1.00e+00 Mindy4b Retreg2
Ambulatory time before self-admin 26304.42 3 2 50 0 1.00e+00 Atg4c Ccny Retreg2
Ambulatory time after self-admin 8900.45 3 2 50 0 1.00e+00 Atg4c Ccny Retreg2
Total heroin consumption 95.23 3 2 50 0 1.00e+00 Atg4c Ccny Retreg2
Area under the delay curve 8275.39 3 2 50 0 1.00e+00 Atg4c Mindy4b Retreg2
Delay disc. indifference point, 0s delay 1084.93 2 1 25 0 1.00e+00 Mindy4b Retreg2
Delay disc. indifference point, 16s delay 5503.46 4 2 50 0.98 1.73e-02 Atg4c Ccny Mindy4b Retreg2
Delay disc. indifference point, 2s delay 60.41 3 1 25 0 1.00e+00 Atg4c Mindy4b Retreg2
Delay disc. indifference point, 24s delay 10820.23 3 1 25 0 1.00e+00 Atg4c Ccny Retreg2
Delay disc. indifference point, 4s delay 169.66 4 2 50 0.98 1.54e-02 Atg4c Ccny Mindy4b Retreg2
Delay disc. indifference point, 8s delay 16687.82 2 1 25 0 1.00e+00 Atg4c Retreg2
Delay discount exponential model param 5653.27 3 2 50 0 1.00e+00 Atg4c Mindy4b Retreg2
Delay discount hyperbolic model param 4106.2 3 2 50 0 1.00e+00 Atg4c Mindy4b Retreg2
Fecal boli incidents, locomotor time 1 30605 2 1 25 0 1.00e+00 Atg4c Retreg2
Change in fecal boli incidents, locomotor task 1909.14 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
Time >=10cm from walls, locomotor time 1 3263.56 4 1 25 0.97 2.84e-02 Atg4c Ccny Mindy4b Retreg2
Bouts of movement, locomotor time 1 5409.06 2 2 50 0 1.00e+00 Ccny Retreg2
Total resting periods, locomotor time 1 1407.78 2 1 25 0 1.00e+00 Ccny Retreg2
Rest time, locomotor task time 1 22349.64 1 1 25 0 1.00e+00 Retreg2
Distance moved, locomotor task time 1 34413.79 2 1 25 0 1.00e+00 Ccny Retreg2
Vertical activity count, locomotor time 1 142354.07 1 1 25 0 1.00e+00 Retreg2
Time >=10cm from walls, locomotor time 2 23732.34 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
Bouts of movement, locomotor time 2 27355.03 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
Total resting periods, locomotor time 2 33023.41 3 2 50 0 1.00e+00 Ccny Mindy4b Retreg2
Rest time, locomotor task time 2 12754.6 2 1 25 0 1.00e+00 Atg4c Retreg2
Distance moved, locomotor task time 2 2131.36 4 2 50 -0.98 2.04e-02 Atg4c Ccny Mindy4b Retreg2
Vertical activity count, locomotor time 2 13402.03 4 2 50 0.98 1.79e-02 Atg4c Ccny Mindy4b Retreg2
Weight adjusted by age 35403.57 2 2 50 0 1.00e+00 Ccny Retreg2
Seeking ratio, delayed vs. immediate footshock 4491.17 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
Locomotion in novel chamber 1954.56 2 1 25 0 1.00e+00 Ccny Retreg2
Locomotion in novel chamber post-restriction 21810.84 3 1 25 0 1.00e+00 Ccny Mindy4b Retreg2
Progressive ratio 16979.1 4 2 50 0.99 1.46e-02 Atg4c Ccny Mindy4b Retreg2
Food seeking constrained by brief footshock 941.95 2 1 25 0 1.00e+00 Atg4c Retreg2
Seeking ratio, punishment vs. effort 20643.93 2 1 25 0 1.00e+00 Ccny Retreg2
Run reversals in cocaine runway, females 9406.04 1 1 25 0 1.00e+00 Retreg2
Run reversals in cocaine runway, males 7664.74 1 1 25 0 1.00e+00 Retreg2
Latency to leave start box in cocaine runway 8153.9 2 1 25 0 1.00e+00 Ccny Retreg2
Latency to leave start box in cocaine runway, F 3588.04 2 1 25 0 1.00e+00 Mindy4b Retreg2
Latency to leave start box in cocaine runway, M 880.56 2 2 50 0 1.00e+00 Ccny Retreg2
Co content in liver 1133.25 1 1 25 0 1.00e+00 Retreg2
Cu content in liver 39.92 1 1 25 0 1.00e+00 Retreg2
Fe content in liver 1344.53 1 1 25 0 1.00e+00 Retreg2
K content in liver 1519.62 1 1 25 0 1.00e+00 Retreg2
Mg content in liver 6026.97 1 1 25 0 1.00e+00 Retreg2
Mn content in liver 1009.39 1 1 25 0 1.00e+00 Retreg2
Na content in liver 4018.36 1 1 25 0 1.00e+00 Retreg2
Rb content in liver 87.87 1 1 25 0 1.00e+00 Retreg2
Zn content in liver 3745.55 1 1 25 0 1.00e+00 Retreg2

Associations by panel

Tissue RNA modality # hits % hits/tests Avg chisq
Adipose alternative polyA 0 0 1.03
Adipose alternative TSS 0 0 1.02
Adipose gene expression 0 0 1.01
Adipose isoform ratio 0 0 1
Adipose intron excision ratio 0 0 0.9
Adipose mRNA stability 0 0 0.98
BLA alternative polyA 0 0 1.07
BLA alternative TSS 0 0 1.02
BLA gene expression 0 0 1.01
BLA isoform ratio 0 0 0.99
BLA intron excision ratio 0 0 0.98
BLA mRNA stability 0 0 1.02
Brain alternative polyA 0 0 1.1
Brain alternative TSS 0 0 1.02
Brain gene expression 0 0 1
Brain isoform ratio 0 0 1.03
Brain intron excision ratio 0 0 0.98
Brain mRNA stability 0 0 1.01
Eye alternative polyA 0 0 0.94
Eye alternative TSS 0 0 0.89
Eye gene expression 0 0 0.99
Eye isoform ratio 0 0 1.04
Eye intron excision ratio 0 0 0.89
Eye mRNA stability 0 0 0.92
IC alternative polyA 0 0 1.27
IC alternative TSS 0 0 1
IC gene expression 0 0 1.03
IC isoform ratio 0 0 1.08
IC intron excision ratio 1 0 1.09
IC mRNA stability 0 0 0.99
IL alternative polyA 0 0 1.09
IL alternative TSS 0 0 0.99
IL gene expression 0 0 1
IL isoform ratio 0 0 1.06
IL intron excision ratio 0 0 0.98
IL mRNA stability 0 0 0.96
LHb alternative polyA 0 0 1.25
LHb alternative TSS 0 0 1.02
LHb gene expression 0 0 0.97
LHb isoform ratio 0 0 1.06
LHb intron excision ratio 0 0 0.94
LHb mRNA stability 0 0 0.98
Liver alternative polyA 0 0 1.03
Liver alternative TSS 0 0 0.96
Liver gene expression 0 0 0.98
Liver isoform ratio 0 0 0.97
Liver intron excision ratio 0 0 0.93
Liver mRNA stability 0 0 0.94
NAcc alternative polyA 1 0 3.02
NAcc alternative TSS 0 0 1.05
NAcc gene expression 0 0 1.01
NAcc isoform ratio 0 0 1.05
NAcc intron excision ratio 1 0 1.03
NAcc mRNA stability 0 0 1.02
OFC alternative polyA 0 0 1.22
OFC alternative TSS 0 0 0.92
OFC gene expression 0 0 1.05
OFC isoform ratio 0 0 1
OFC intron excision ratio 0 0 1.04
OFC mRNA stability 0 0 0.98
PL alternative polyA 0 0 1.11
PL alternative TSS 0 0 1.03
PL gene expression 0 0 1.01
PL isoform ratio 0 0 1.04
PL intron excision ratio 0 0 1.01
PL mRNA stability 0 0 1.01
pVTA alternative polyA 0 0 1.21
pVTA alternative TSS 0 0 1.11
pVTA gene expression 1 0 1
pVTA isoform ratio 0 0 1.09
pVTA intron excision ratio 0 0 1.04
pVTA mRNA stability 0 0 1.02
RMTg alternative polyA 0 0 1.06
RMTg alternative TSS 0 0 0.96
RMTg gene expression 0 0 1.03
RMTg isoform ratio 0 0 0.99
RMTg intron excision ratio 0 0 0.99
RMTg mRNA stability 0 0 1.07