Hub : Genes

Clec3b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Clec3b 0.16 0.14 5.5e-05 0.09 0.05 0.09 0.03 1.3e-04 4.1e-03 9.1e-05 2.2e-02
2 Adipose gene expression Clec3b 0.16 0.19 1.0e-10 0.08 0.07 0.1 0.07 3.8e-09 2.2e-08 9.3e-11 1.1e-08
3 Eye gene expression Clec3b 0.65 0.77 1.9e-04 0.27 0.19 0.26 0.06 4.7e-05 8.3e-04 7.0e-05 4.6e-02
4 RMTg gene expression Clec3b 0.78 0.22 5.0e-04 0.08 0.08 0.07 0.08 3.0e-03 4.2e-03 5.5e-03 4.1e-03
5 BLA gene expression Clec3b 0.07 0.07 1.5e-03 0.04 0.04 0.04 0.04 2.5e-03 2.6e-03 2.9e-03 3.7e-03
6 NAcc gene expression Clec3b 0.15 0.13 0.0e+00 0.12 0.13 0.12 0.13 1.8e-18 3.7e-19 5.4e-18 1.1e-18
7 pVTA gene expression Clec3b 0.24 0.17 0.0e+00 0.2 0.22 0.2 0.17 5.7e-16 1.4e-17 3.1e-16 2.4e-13
8 Brain gene expression Clec3b 0.21 0.16 0.0e+00 0.2 0.2 0.2 0.2 3.6e-18 3.0e-18 3.4e-18 3.5e-18
9 Adipose mRNA stability Clec3b 0.09 0.08 7.8e-09 0.05 0.06 0.05 0.05 6.9e-06 2.9e-07 1.8e-06 1.4e-06
10 PL gene expression Clec3b 0.08 0.07 1.0e-07 0.06 0.07 0.07 0.07 1.4e-07 4.1e-08 9.2e-08 1.1e-07
11 Liver gene expression Clec3b 0.03 0.03 7.0e-03 0.01 0.01 0.01 0.01 4.9e-02 4.0e-02 3.3e-02 5.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.81.41.9-0.9-1.31.21.21.41.21.21.21.21.21.1
Area under the delay curve0.70.81.5-0.90.3-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-1.2
BMI with tail1.44.86.70.32.1-2.2-2.3-2.3-2.3-2.3-2.3-2.3-2.3-2.6
BMI without tail0.51.42.50.51.5-1.1-1.2-1.2-1.1-1.2-1.2-1.2-1.2-1.6
Body weight0.10.30.8-0.9-0.30.60.60.50.50.50.50.50.5-0.0
Weight adjusted by age1.11.74.02.00.71.31.21.21.21.21.21.21.21.2
Bone surface0.00.00.10.00.30.20.20.20.10.10.10.10.1-0.2
Bone volume0.10.20.70.40.8-0.4-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.7
Breakpoint value in progressive ratio session3.23.928.55.33.20.60.70.60.70.70.70.70.70.6
Number of licking bursts0.81.43.31.81.6-1.1-1.1-1.0-1.0-1.0-1.0-1.0-1.0-0.9
Context. condit. distance diff. score0.10.11.2-1.1-0.4-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.3
Locomotion velocity, session 10.30.31.7-1.3-0.90.20.20.30.30.30.30.30.30.2
Locomotion distance, session 11.82.317.2-4.2-2.8-0.0-0.00.00.00.00.00.00.00.1
Locomotion velocity, session 20.91.07.3-2.7-2.0-0.0-0.00.0-0.0-0.0-0.0-0.0-0.00.2
Locomotion distance, session 22.43.322.7-4.8-3.40.30.30.50.40.40.40.40.40.5
Locomotion velocity, session 30.40.52.51.60.20.40.40.60.50.50.50.50.50.8
Locomotion distance, session 30.20.21.71.30.7-0.1-0.10.20.00.00.10.10.10.2
Stereotopy head waving bouts, day 31.31.611.23.42.40.30.30.30.30.30.30.30.30.1
Stereotopy head waving duration, day 31.21.59.93.12.5-0.1-0.1-0.2-0.1-0.1-0.1-0.1-0.1-0.3
Locomotion velocity, session 70.30.31.5-1.2-0.6-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4
Locomotion distance, session 71.51.83.2-1.6-1.81.31.31.31.31.31.31.31.31.2
Stereotopy head waving bouts, day 73.33.824.04.93.3-1.0-1.0-0.8-0.9-0.9-0.9-0.9-0.9-0.6
Stereotopy head waving duration, day 73.74.525.75.13.5-1.3-1.3-1.0-1.2-1.2-1.1-1.2-1.1-0.9
Locomotion velocity, session 80.40.42.7-1.6-0.7-0.5-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.4
Locomotion distance, session 81.11.611.9-3.4-2.30.20.20.40.30.30.30.30.30.2
Degree of sensitization distance1.61.610.6-3.3-2.10.70.70.40.60.60.50.50.50.3
Degree of sensitization stereotypy3.84.119.04.42.9-1.6-1.6-1.4-1.5-1.5-1.5-1.5-1.5-0.9
Conditioned locomotion0.70.81.0-0.30.6-1.0-0.9-1.0-1.0-1.0-1.0-1.0-1.0-1.0
Cocaine response after cond. corrected0.40.40.90.8-0.40.70.70.60.60.60.60.60.61.0
Cocaine response after cond. not corrected0.70.81.41.0-0.40.90.90.90.90.90.90.90.91.2
Cocaine response before conditioning0.10.21.01.00.70.20.10.20.20.20.20.20.2-0.0
Saline control response0.91.22.1-1.3-1.41.11.01.01.01.01.01.01.00.9
Bone: connectivity density1.82.83.7-0.2-1.61.71.71.91.71.71.71.71.71.8
Bone: cortical apparent density2.53.525.1-5.0-3.30.50.50.50.50.50.50.50.50.4
Bone: cortical area1.11.612.9-3.6-1.60.70.70.40.50.50.50.50.5-0.1
Bone: cortical porosity2.12.317.24.12.10.70.70.50.60.60.60.60.60.7
Bone: cortical porosity1.31.47.52.71.30.90.90.80.90.90.80.90.80.8
Bone: cortical thickness3.86.336.1-6.0-3.81.51.51.41.41.51.41.41.40.9
Bone: cortical thickness4.24.96.4-2.5-2.02.32.32.22.22.22.22.22.21.6
Bone: cortical tissue density2.22.921.1-4.6-3.10.40.40.40.50.50.50.50.50.4
Condit. Reinf. active minus inactive responses0.40.50.6-0.50.1-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7
Condit. Reinf. active-inactive response ratio0.50.60.70.00.5-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8
Condit. Reinf. active responses1.31.710.2-3.2-1.4-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.9
Condit. Reinf. inactive responses1.82.313.6-3.7-1.5-0.9-0.9-1.0-1.0-1.0-1.0-1.0-1.0-1.1
Incentive salience index mean0.91.28.5-2.9-1.4-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.6
Condit. Reinf. lever presses1.62.319.1-4.4-2.40.10.10.10.10.10.10.10.1-0.2
Condit. Reinf. active minus inactive responses3.64.66.0-1.10.9-2.3-2.3-2.3-2.3-2.3-2.3-2.3-2.3-2.5
Condit. Reinf. active-inactive response ratio2.63.09.6-3.1-0.6-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.8
Condit. Reinf. active responses4.66.48.10.22.1-2.7-2.7-2.7-2.7-2.7-2.7-2.7-2.7-2.9
Condit. Reinf. inactive responses5.57.122.64.84.0-2.1-2.1-2.1-2.1-2.1-2.1-2.1-2.1-1.9
Condit. Reinf. lever presses2.33.16.11.12.5-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.7-2.1
Condit. Reinf. lever reinforcers received5.47.59.30.32.3-2.9-2.9-3.0-2.9-2.9-2.9-2.9-2.9-3.1
Conditioned reinforcement - actives0.20.40.5-0.20.3-0.7-0.7-0.6-0.7-0.7-0.7-0.7-0.7-0.7
Conditioned reinforcement - inactives0.10.10.5-0.7-0.70.00.0-0.10.00.00.00.00.00.0
Conditioned locomotion1.41.82.7-1.4-1.61.31.31.51.31.31.31.31.31.2
Patch foraging indifference point 0 sec0.91.74.5-2.1-1.51.31.31.21.21.21.21.21.20.8
Patch foraging indifference point AUC0.20.20.3-0.10.2-0.5-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.6
Delay disc. indifference point, 0s delay0.00.00.0-0.10.1-0.1-0.0-0.1-0.0-0.0-0.1-0.1-0.1-0.2
Delay disc. indifference point, 16s delay0.60.71.10.30.9-0.9-0.8-0.8-0.8-0.9-0.8-0.9-0.8-1.0
Delay disc. indifference point, 2s delay1.31.41.8-1.30.0-1.3-1.3-1.2-1.2-1.2-1.2-1.2-1.2-1.3
Delay disc. indifference point, 24s delay1.41.613.5-3.7-1.90.20.20.00.10.10.10.10.1-0.2
Delay disc. indifference point, 4s delay3.53.75.00.72.1-2.0-2.0-2.1-1.9-1.9-1.9-1.9-1.9-2.2
Delay disc. indifference point, 8s delay0.30.42.6-1.6-1.00.30.30.20.20.20.20.20.20.0
Indifference point function ln k1.32.25.0-2.2-2.11.31.31.31.31.31.31.31.31.3
Indifference point function log k1.32.25.0-2.2-2.11.31.31.31.31.31.31.31.31.3
Patch foraging total patch changes 0 sec0.71.32.0-1.4-1.11.21.31.21.11.11.11.11.10.8
Patch foraging total patch changes 12 sec0.10.10.8-0.90.10.30.30.10.10.10.10.10.1-0.2
Patch foraging total patch changes 18 sec1.01.51.9-1.2-0.1-1.2-1.3-1.2-1.3-1.3-1.3-1.3-1.3-1.4
Patch foraging total patch changes 24 sec0.50.91.1-0.9-1.11.01.01.00.90.90.90.90.90.8
Patch foraging total patch changes 6 sec0.50.83.51.91.6-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.6
Patch foraging time to switch 0 sec0.91.83.01.71.7-1.2-1.3-1.4-1.3-1.3-1.3-1.3-1.3-1.0
Patch foraging water rate 0 sec0.20.40.7-0.1-0.20.70.80.90.70.70.70.70.70.4
Patch foraging water rate 12 sec0.10.20.9-0.9-0.7-0.3-0.3-0.3-0.3-0.4-0.3-0.3-0.3-0.3
Patch foraging water rate 18 sec0.81.21.40.91.1-1.2-1.2-1.1-1.1-1.1-1.1-1.1-1.1-1.0
Patch foraging water rate 24 sec1.31.92.30.41.3-1.5-1.5-1.4-1.4-1.4-1.4-1.4-1.4-1.5
Patch foraging water rate 6 sec0.20.21.00.71.0-0.3-0.3-0.4-0.4-0.4-0.4-0.4-0.4-0.6
Seeking ratio, delayed vs. immediate footshock0.30.41.61.30.7-0.6-0.6-0.4-0.5-0.5-0.5-0.5-0.5-0.2
Distance traveled before self-admin0.00.00.10.2-0.10.10.10.30.20.20.20.20.20.3
Distance traveled after self-admin0.10.10.20.5-0.20.10.10.30.20.20.20.20.20.4
Extensor digitorum longus weight0.31.21.5-0.50.4-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2
Bone: elastic displacement5.26.040.8-6.4-4.50.80.80.70.80.80.80.80.80.7
Bone: elastic work3.24.228.4-5.3-3.50.80.80.70.80.80.80.80.80.5
Bone: endosteal estimation0.81.810.53.22.7-0.4-0.4-0.5-0.4-0.4-0.4-0.4-0.4-0.6
Bone: endosteal perimeter2.86.014.72.93.8-2.1-2.1-2.3-2.1-2.1-2.1-2.1-2.1-2.5
Epididymis fat weight0.20.61.3-0.70.5-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-1.1
Delta time in closed arm before/after self-admin0.60.62.6-1.6-1.10.60.50.60.50.50.60.50.60.5
Delta time in open arm before/after self-admin1.00.92.01.40.20.81.01.11.01.01.01.01.00.9
Diff in mean of infusions in LGA sessions0.70.95.72.41.00.50.60.50.50.50.50.50.50.7
Delay discount exponential model param0.91.01.71.2-0.31.01.01.01.01.01.01.01.01.3
Extinction: sum of active levers before priming2.22.412.93.62.7-0.9-0.8-0.9-0.8-0.8-0.8-0.8-0.8-0.8
Active lever presses in extinction session 61.71.72.61.41.6-1.3-1.3-1.2-1.3-1.3-1.2-1.2-1.2-1.1
Bone: final force1.42.213.1-3.6-1.81.01.00.91.01.01.01.01.00.3
Bone: final moment1.93.020.1-4.5-2.41.01.00.91.01.00.91.01.00.3
Food consumed during 24 hour testing period1.41.92.60.4-0.01.61.61.51.61.61.61.61.61.1
Glucose1.21.92.2-1.1-1.31.41.41.51.41.41.41.41.41.3
Heart weight0.20.40.50.5-0.10.70.70.70.60.60.60.60.60.5
Delay discount hyperbolic model param0.80.91.61.1-0.31.00.91.00.90.90.91.01.01.3
Intermittent access intake day 1-15 change0.10.20.40.70.20.50.50.50.50.50.50.50.50.4
Intermittent access intake escalation0.20.53.51.91.30.20.20.20.20.10.10.10.1-0.0
Intermittent access intake escalation 20.70.82.31.51.4-0.7-0.7-0.6-0.7-0.7-0.7-0.7-0.7-0.8
Intermitt. access day 1 inactive lever presses0.82.84.5-1.0-2.11.61.61.61.71.71.71.71.71.9
Intermitt. access day 15 inactive lever presses2.04.14.8-1.4-2.22.12.12.02.12.12.12.12.12.0
Intermitt. access escalation Index1.92.63.3-0.2-0.91.81.81.71.81.81.81.81.81.7
Intermittent access day 1 total infusions0.40.63.6-1.9-1.0-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5
Intermittent access day 15 total infusions0.00.00.10.10.3-0.0-0.0-0.1-0.1-0.1-0.1-0.1-0.1-0.3
Intermittent access terminal intake (last 3 days)0.60.81.2-0.60.3-0.9-0.9-0.9-0.9-1.0-1.0-1.0-1.0-1.1
Intermittent access total infusions0.30.42.5-1.6-0.7-0.4-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.5
Intermittent access day 1 locomotion1.72.22.6-0.9-1.51.51.51.61.51.51.51.51.51.4
Intermittent access day 15 total locomotion0.50.81.00.8-0.11.01.01.01.01.01.01.01.00.9
Intermittent access total locomotion0.30.40.60.4-0.10.70.70.80.70.70.70.70.70.5
Intermittent access standard deviation1.42.94.0-1.5-2.01.71.71.81.71.71.71.71.71.7
Left kidney weight0.00.10.8-0.9-0.10.20.20.30.20.20.20.20.2-0.3
Right kidney weight0.00.00.2-0.10.5-0.1-0.1-0.0-0.1-0.1-0.1-0.1-0.1-0.5
Cocaine induced anxiety2.33.43.7-1.1-1.71.91.91.91.91.91.91.91.91.8
Post-drug Anxiety1.21.21.50.1-0.71.21.21.21.21.21.21.21.21.1
Baseline Anxiety1.82.12.31.31.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.3
Tail length0.72.73.50.5-0.61.81.91.81.81.81.81.81.81.6
Length with tail2.39.911.4-2.0-3.03.43.43.33.33.33.33.33.33.0
Length without tail0.82.53.2-0.5-1.21.81.81.71.71.71.71.71.71.6
Times rat made contact with spout1.21.41.7-1.3-1.21.21.21.21.21.21.21.21.20.9
Lifetime Intake0.30.42.8-1.7-1.0-0.1-0.1-0.0-0.1-0.1-0.1-0.1-0.1-0.3
Liver weight, left0.30.40.6-0.7-0.20.80.80.60.70.70.70.70.70.3
Liver weight, right2.74.630.9-5.6-3.80.90.90.80.80.80.80.80.80.7
Locomotor activity0.20.31.4-1.2-0.80.30.40.50.40.40.40.40.40.2
Locomotor testing distance0.50.93.2-1.8-1.70.60.60.70.60.60.60.60.60.6
Locomotor testing rearing0.20.32.3-1.5-1.0-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2
Locomotion in novel chamber2.32.94.00.4-0.31.92.01.91.91.91.91.91.91.6
Locomotion in novel chamber post-restriction0.10.20.70.40.80.40.40.30.30.30.30.30.3-0.1
Fecal boli incidents, locomotor time 10.20.20.5-0.5-0.70.40.40.60.40.40.40.40.40.5
Change in fecal boli incidents, locomotor task0.60.61.8-1.3-0.0-0.8-0.7-0.6-0.6-0.6-0.6-0.6-0.6-1.0
Time >=10cm from walls, locomotor time 10.00.00.0-0.1-0.10.00.00.00.10.10.10.10.1-0.0
Bouts of movement, locomotor time 10.70.81.50.31.2-0.7-0.7-0.9-0.9-0.9-0.9-0.9-0.9-1.2
Total resting periods, locomotor time 10.40.51.0-0.20.8-0.6-0.5-0.7-0.7-0.7-0.7-0.7-0.7-1.0
Rest time, locomotor task time 10.60.81.30.50.31.01.10.91.01.01.01.01.00.6
Distance moved, locomotor task time 10.10.10.5-0.4-0.70.30.20.30.30.30.30.30.30.4
Vertical activity count, locomotor time 10.10.30.7-0.5-0.80.50.40.50.60.60.60.60.60.6
Time >=10cm from walls, locomotor time 20.60.95.42.31.20.50.50.70.70.60.70.60.60.5
Bouts of movement, locomotor time 20.91.52.10.30.8-1.4-1.3-1.2-1.4-1.4-1.3-1.3-1.3-1.2
Total resting periods, locomotor time 21.11.92.6-0.30.5-1.6-1.5-1.4-1.6-1.5-1.5-1.5-1.5-1.3
Rest time, locomotor task time 20.91.12.1-1.4-0.1-1.1-0.9-1.1-1.1-1.1-1.1-1.1-1.1-1.2
Distance moved, locomotor task time 23.03.65.62.40.22.01.91.92.02.02.02.02.02.0
Vertical activity count, locomotor time 22.94.05.11.4-0.62.12.02.12.22.12.22.12.12.3
Light reinforcement 10.41.01.60.91.2-1.0-1.0-0.9-0.9-0.9-0.9-0.9-0.9-1.0
Light reinforcement 20.20.32.11.41.1-0.1-0.10.10.00.10.10.10.10.0
Bone: marrow area0.81.810.33.22.7-0.5-0.5-0.6-0.5-0.5-0.5-0.5-0.5-0.7
Bone: maximum diameter0.81.55.41.52.3-0.8-0.8-1.0-0.9-0.9-0.9-0.9-0.9-1.4
Bone: maximum force1.11.94.5-2.1-1.31.41.41.31.31.31.31.31.30.8
Bone: maximum moment1.42.58.7-3.0-1.81.41.41.31.41.31.31.31.30.8
Mean time between licks in bursts1.02.42.9-0.8-1.11.71.71.71.71.71.71.71.71.4
Mean num. licks in bursts2.74.37.8-2.8-2.52.02.02.01.91.91.91.91.91.6
Cd content in liver0.30.30.80.90.00.50.50.50.50.50.50.50.50.7
Co content in liver0.30.30.4-0.60.1-0.6-0.6-0.7-0.6-0.6-0.6-0.6-0.6-0.6
Cu content in liver5.46.416.13.54.0-2.1-2.1-2.1-2.1-2.1-2.1-2.1-2.1-2.4
Fe content in liver0.30.31.71.31.3-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.4
K content in liver2.52.43.00.61.6-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.7
Mg content in liver1.11.11.8-0.80.6-1.1-1.1-1.1-1.1-1.0-1.1-1.1-1.1-1.3
Mn content in liver0.30.31.51.20.8-0.5-0.5-0.5-0.4-0.4-0.4-0.4-0.4-0.2
Na content in liver1.51.63.8-1.9-0.3-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.4
Rb content in liver2.83.39.23.02.9-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4
Se content in liver0.60.85.62.41.6-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.2
Sr content in liver2.62.32.50.81.3-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.5
Zn content in liver0.40.51.7-1.3-0.90.60.60.50.60.60.50.50.50.4
Bone: minimum diameter0.00.10.4-0.60.10.30.30.20.30.30.20.30.3-0.1
Time in familiar zone, hab. session 11.71.712.73.62.4-0.1-0.1-0.0-0.1-0.1-0.0-0.1-0.0-0.1
Time in novel zone, hab. session 11.11.16.7-2.6-1.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.4
Total zone transitions, hab. session 10.30.42.3-1.5-1.2-0.2-0.2-0.3-0.2-0.2-0.2-0.2-0.20.0
Total locomotion distance, hab. session 11.21.62.6-1.6-0.6-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.1
Locomotion velocity, hab. session 11.42.02.8-1.7-0.4-1.5-1.4-1.4-1.5-1.5-1.5-1.5-1.5-1.3
Time in familiar zone, hab. session 20.30.43.01.70.9-0.2-0.2-0.1-0.1-0.1-0.1-0.1-0.10.0
Time in novel zone, hab. session 20.80.81.40.51.2-0.8-0.8-1.0-0.9-0.9-0.9-0.9-0.9-1.1
Total zone transitions, hab. session 20.81.07.6-2.8-1.9-0.1-0.10.0-0.0-0.0-0.0-0.0-0.00.0
Total locomotion distance, hab. session 21.21.511.4-3.4-2.2-0.3-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.2
Locomotion velocity, hab. session 22.33.123.8-4.9-3.2-0.2-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.0
Novel to familiar place preference ratio1.41.59.43.12.20.60.60.50.60.60.50.60.60.2
Novelty place preference1.71.812.23.52.50.40.40.30.40.40.40.40.40.0
Time in novel zone, NPP test2.12.215.13.93.00.30.30.20.20.20.20.20.2-0.1
Total zone transitions, NPP test2.03.017.5-4.2-3.30.50.60.80.70.70.70.70.70.7
Total locomotion distance, NPP test0.91.36.5-2.6-2.1-0.8-0.8-0.5-0.6-0.6-0.6-0.6-0.6-0.1
Locomotion velocity, NPP test0.91.37.2-2.7-2.2-0.6-0.6-0.4-0.5-0.5-0.5-0.5-0.5-0.0
Intraocular pressure2.73.94.9-1.8-0.1-2.2-2.2-2.1-2.1-2.1-2.1-2.1-2.1-2.0
Delta distance traveled before/after self-admin0.40.50.60.30.3-0.7-0.8-0.7-0.7-0.8-0.7-0.7-0.7-0.6
Delta ambulatory time before/after self-admin0.70.91.2-0.3-0.0-1.1-1.1-1.0-1.0-1.0-1.0-1.0-1.0-0.8
Parametrial fat weight1.33.15.4-2.3-2.21.71.71.61.71.71.71.71.71.4
Pavlov. Cond. lever latency3.34.222.64.83.2-1.3-1.3-1.1-1.2-1.3-1.2-1.2-1.2-0.8
Pavlov. Cond. magazine entry latency2.02.612.3-3.5-1.5-1.2-1.2-1.3-1.2-1.2-1.2-1.2-1.2-1.2
Pavlov. Cond. change in total contacts3.63.826.9-5.2-3.30.80.70.60.70.70.70.70.70.4
Pavlov. Cond. index score2.93.729.2-5.4-3.30.30.30.10.30.30.20.30.30.0
Pavlov. Cond. latency score2.53.223.4-4.8-3.10.60.60.40.50.50.50.50.50.3
Pavlov. Cond. lever contacts5.76.843.6-6.6-4.41.21.21.11.21.21.21.21.20.8
Pavlov. Cond. magazine entry number1.62.010.93.31.40.91.01.11.01.01.01.01.01.0
Pavlov. Cond. intertrial magazine entries0.70.86.02.41.80.10.1-0.00.00.00.00.00.0-0.1
Pavlov. Cond. lever-magazine prob. diff.3.54.434.7-5.9-3.60.30.30.10.20.20.20.20.20.0
Pavlov. Cond. response bias3.24.033.1-5.8-3.1-0.3-0.3-0.4-0.3-0.3-0.4-0.4-0.4-0.6
Pavlov. Cond. lever latency0.81.01.7-0.3-1.31.01.01.01.01.01.01.01.01.3
Pavlov. Cond. magazine entry latency0.30.41.51.11.2-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.6
Pavlov. Cond. change in total contacts0.91.52.6-1.60.5-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.6
Pavlov. Cond. index score0.81.11.9-0.21.0-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.4
Pavlov. Cond. latency score0.81.11.80.51.3-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.3
Pavlov. Cond. lever contacts0.60.91.50.21.2-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-1.2
Pavlov. Cond. magazine entry number0.60.71.10.2-0.70.90.90.90.90.90.90.90.91.1
Pavlov. Cond. intertrial magazine entries0.81.15.72.41.6-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.6
Pavlov. Cond. lever-magazine prob. diff.1.11.42.5-0.60.9-1.3-1.3-1.2-1.2-1.2-1.2-1.2-1.2-1.6
Pavlov. Cond. response bias0.91.22.1-0.60.8-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.4
Time in closed arm before self-admin8.510.913.30.72.3-3.6-3.5-3.5-3.6-3.6-3.6-3.6-3.6-3.4
Time in closed arm after self-admin10.811.513.01.33.0-3.6-3.6-3.6-3.6-3.6-3.6-3.6-3.6-3.5
Time in open arm before self-admin1.61.82.40.2-0.21.61.51.41.51.51.51.51.51.3
Time in open arm after self-admin6.47.18.5-0.1-1.72.92.92.92.92.92.92.92.92.8
Bone: periosteal estimation0.00.10.8-0.00.90.10.1-0.20.00.0-0.0-0.0-0.0-0.5
Bone: periosteal perimeter1.01.83.4-0.71.2-1.2-1.2-1.5-1.3-1.3-1.3-1.3-1.3-1.8
Bone: post-yield work2.53.722.74.82.41.11.11.21.21.21.21.21.21.1
Progressive ratio test 1 active lever presses0.50.74.5-2.1-0.9-0.4-0.4-0.3-0.4-0.5-0.5-0.5-0.5-0.7
Progressive ratio test 1 breakpoint0.50.64.6-2.1-1.0-0.4-0.4-0.2-0.4-0.4-0.4-0.4-0.4-0.6
Progressive ratio test 1 inactive lever presses0.20.31.5-1.2-1.20.20.20.40.20.20.20.20.20.3
Progressive ratio test 2 active lever presses0.10.21.1-1.1-0.4-0.2-0.2-0.2-0.2-0.3-0.3-0.3-0.3-0.4
Progressive ratio test 2 breakpoint0.20.31.1-1.0-0.3-0.4-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.5
Progressive ratio test 2 inactive lever presses0.10.10.10.1-0.20.30.30.40.30.30.30.30.30.3
Incentive Sensitization - Responses0.10.10.30.60.20.20.20.20.20.20.20.20.20.2
Incentive Sensitization - Breakpoint0.10.10.50.70.50.00.0-0.00.10.10.00.10.10.0
Sum of active levers in priming session hrs 5-62.42.26.82.62.4-1.1-1.2-1.1-1.1-1.1-1.1-1.1-1.1-1.2
Progressive ratio0.40.72.6-1.6-1.40.50.50.50.60.60.60.60.60.8
Food seeking constrained by brief footshock1.11.37.5-2.7-1.1-0.8-0.8-0.7-0.8-0.8-0.8-0.8-0.8-0.8
Seeking ratio, punishment vs. effort0.91.21.91.01.4-1.0-1.0-1.0-1.1-1.1-1.1-1.1-1.1-1.3
Retroperitoneal fat weight0.20.81.6-0.40.7-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-1.3
Reaction time number correct0.10.10.2-0.2-0.1-0.4-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.3
Reaction time mean minus median0.20.53.6-1.9-1.40.10.1-0.10.00.00.00.00.00.1
Reaction time mean minus median AUC0.61.410.6-3.2-2.20.10.0-0.2-0.1-0.1-0.1-0.1-0.10.0
Reaction time num false alarms0.20.31.71.31.00.10.10.10.20.20.20.20.20.0
Reaction time num false alarms AUC0.30.40.50.3-0.00.60.70.70.70.70.70.70.70.6
Reaction time trials correct on left0.10.10.2-0.2-0.1-0.4-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.3
Reaction time trials on left0.10.10.1-0.3-0.2-0.4-0.4-0.2-0.3-0.4-0.4-0.4-0.4-0.3
Reaction time mean1.32.115.6-4.0-2.2-0.4-0.4-0.8-0.6-0.5-0.6-0.6-0.6-0.5
Reaction time mean AUC1.01.610.6-3.3-1.8-0.5-0.5-0.8-0.7-0.6-0.7-0.7-0.7-0.5
Median of all reaction times1.31.911.4-3.4-1.5-0.7-0.7-1.1-0.9-0.9-0.9-0.9-0.9-0.9
Reaction time omissions0.60.82.3-1.5-0.80.90.90.80.90.90.80.90.80.3
Reaction time false alarm rate0.40.60.9-0.9-0.70.70.80.70.80.80.80.80.80.7
Reaction time premature initiation rate0.20.31.3-1.2-1.10.20.10.20.30.30.20.30.20.4
Reaction time premature initiations0.20.41.5-1.1-1.20.30.30.40.40.40.40.40.40.5
Std. dev. reaction times1.83.321.2-4.6-3.30.90.80.50.70.70.70.70.70.7
Reaction time trials completed0.10.10.1-0.3-0.2-0.4-0.4-0.2-0.3-0.4-0.4-0.4-0.4-0.3
Reaction time trials AUC0.10.10.4-0.7-0.5-0.3-0.2-0.1-0.2-0.2-0.2-0.2-0.2-0.2
Run reversals in cocaine runway, females1.91.93.7-1.9-1.71.31.21.21.31.31.31.31.31.2
Run reversals in cocaine runway, males0.50.54.2-2.1-1.3-0.00.1-0.0-0.0-0.0-0.0-0.0-0.0-0.0
Latency to leave start box in cocaine runway0.80.91.51.21.2-0.9-1.0-0.8-0.9-0.9-0.9-0.9-0.9-0.8
Latency to leave start box in cocaine runway, F0.10.10.6-0.7-0.5-0.1-0.3-0.0-0.1-0.2-0.1-0.1-0.1-0.1
Latency to leave start box in cocaine runway, M1.41.32.81.71.6-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0
Std. dev. time between licks in bursts1.41.913.93.72.60.10.10.20.20.20.20.20.20.0
Total sessions with >9 infusions0.10.20.8-0.9-0.4-0.3-0.3-0.1-0.3-0.3-0.3-0.3-0.3-0.5
Short access day 1 total inactive lever presses0.40.53.6-1.9-1.3-0.0-0.00.1-0.0-0.0-0.0-0.0-0.0-0.1
Short access day 10 total inactive lever presses2.76.68.5-0.3-2.12.72.72.82.72.72.72.72.72.9
Short access day 1 total infusions0.10.10.7-0.8-0.60.00.00.20.00.00.00.00.0-0.1
Short access day 10 total infusions0.10.10.8-0.9-0.7-0.2-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.1
Short access total infusions0.30.42.8-1.7-1.20.10.10.30.10.10.10.10.1-0.1
Short access day 1 locomotion0.20.21.51.20.60.20.20.30.20.20.20.20.20.2
Short access day 10 total locomotion0.71.41.70.9-0.21.31.31.31.31.21.21.21.21.2
Short access total locomotion0.30.40.60.3-0.20.70.70.80.70.60.60.60.60.6
One hour access (0.3 mA shock)0.10.10.1-0.4-0.1-0.2-0.2-0.3-0.2-0.2-0.3-0.3-0.3-0.3
Compulsive drug intake0.70.81.6-0.6-1.20.80.80.90.80.80.80.80.81.0
One hour access (shock baseline)0.10.10.2-0.20.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.5
Social response proportion3.64.18.22.02.9-1.9-1.8-1.9-1.9-1.9-1.9-1.9-1.9-2.2
Social responses1.01.32.30.81.5-1.2-1.1-1.0-1.0-1.0-1.1-1.0-1.0-1.4
Social time1.82.42.90.91.6-1.7-1.7-1.5-1.6-1.6-1.6-1.6-1.6-1.6
Soleus weight0.41.14.5-2.1-1.60.80.80.80.80.80.80.80.80.6
Bone: stiffness0.50.84.42.12.00.20.20.20.20.20.10.20.1-0.3
Tibialis anterior weight0.51.61.91.31.2-1.4-1.4-1.2-1.3-1.3-1.3-1.3-1.3-1.1
Time to tail flick, vehicle, before self-admin1.51.610.63.32.10.60.50.40.50.50.50.50.50.4
Time to tail flick, vehicle, after self-admin1.92.53.00.51.4-1.7-1.6-1.7-1.7-1.7-1.7-1.7-1.7-1.7
Time to tail flick, test, before self-admin2.52.63.20.01.2-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.8
Time to tail flick, test, after self-admin0.91.05.4-2.3-1.1-0.6-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.5
Delta time to tail flick, vehicle, before/after SA1.31.24.6-2.1-0.8-1.0-0.9-1.0-1.0-1.0-1.0-1.0-1.0-0.9
Delta time to tail flick, test, before/after SA1.11.14.0-2.0-2.00.70.70.70.70.70.70.70.70.8
Tibia length1.33.512.5-3.5-2.61.61.61.51.51.51.51.51.51.1
Ambulatory time before self-admin0.20.42.61.61.00.10.20.20.20.20.20.20.20.2
Ambulatory time after self-admin0.10.10.70.80.2-0.2-0.20.0-0.1-0.1-0.1-0.1-0.10.1
Bone: tissue strength0.60.65.1-2.3-1.0-0.2-0.2-0.2-0.1-0.1-0.2-0.1-0.1-0.4
Total heroin consumption1.31.512.33.52.1-0.2-0.2-0.0-0.0-0.0-0.0-0.0-0.00.1
Bone: trabecular number0.71.11.7-0.5-1.11.01.01.31.11.11.11.11.11.0
Bone: trabecular spacing0.00.00.1-0.2-0.2-0.0-0.0-0.2-0.1-0.1-0.1-0.1-0.10.1
Bone: trabecular thickness0.10.20.30.30.30.40.40.60.50.50.50.50.50.1
Bone: trabecular tissue density0.10.21.5-1.2-0.10.10.1-0.10.10.10.00.10.1-0.4
Water consumed over 24 hours0.00.00.10.1-0.30.20.20.20.20.20.20.20.20.3
Number of responses in last shaping day0.60.71.30.51.1-0.8-0.8-0.6-0.8-0.8-0.8-0.8-0.8-1.0