Hub : Genes

Clec3b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Clec3b 0.16 0.14 5.5e-05 0.09 0.05 0.09 0.03 1.3e-04 4.1e-03 9.1e-05 2.5e-02
2 Adipose gene expression Clec3b 0.16 0.19 1.0e-10 0.08 0.07 0.1 0.07 3.8e-09 2.2e-08 9.3e-11 1.0e-08
3 Eye gene expression Clec3b 0.65 0.77 1.9e-04 0.27 0.19 0.26 0.06 4.7e-05 8.3e-04 7.1e-05 4.7e-02
4 RMTg gene expression Clec3b 0.78 0.22 5.0e-04 0.08 0.08 0.07 0.08 3.0e-03 4.2e-03 5.6e-03 4.0e-03
5 BLA gene expression Clec3b 0.07 0.07 1.5e-03 0.04 0.04 0.04 0.04 2.5e-03 2.6e-03 2.8e-03 3.4e-03
6 NAcc gene expression Clec3b 0.15 0.13 0.0e+00 0.12 0.13 0.12 0.13 1.8e-18 3.7e-19 5.4e-18 1.1e-18
7 pVTA gene expression Clec3b 0.24 0.17 0.0e+00 0.2 0.22 0.2 0.17 5.7e-16 1.4e-17 3.1e-16 2.2e-13
8 Brain gene expression Clec3b 0.21 0.16 0.0e+00 0.2 0.2 0.2 0.2 3.6e-18 3.0e-18 3.2e-18 3.5e-18
9 Adipose mRNA stability Clec3b 0.09 0.08 7.8e-09 0.05 0.06 0.05 0.05 6.9e-06 2.9e-07 1.8e-06 1.4e-06
10 PL gene expression Clec3b 0.08 0.07 1.0e-07 0.06 0.07 0.07 0.07 1.4e-07 4.1e-08 9.3e-08 1.0e-07
11 Liver gene expression Clec3b 0.03 0.03 7.0e-03 0.01 0.01 0.01 0.01 4.9e-02 4.0e-02 3.3e-02 5.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.81.41.90.91.3-1.2-1.2-1.41.21.21.21.21.2-1.1
Area under the delay curve0.50.81.50.9-0.30.90.90.9-0.9-0.9-0.9-0.9-0.91.2
BMI with tail1.44.86.7-0.3-2.12.22.32.3-2.3-2.3-2.3-2.3-2.32.6
BMI without tail0.31.42.5-0.5-1.51.11.21.2-1.1-1.2-1.2-1.2-1.21.6
Body weight0.10.30.80.90.3-0.6-0.6-0.50.50.50.50.50.50.0
Weight adjusted by age0.61.74.0-2.0-0.7-1.3-1.2-1.21.21.21.21.21.2-1.2
Bone surface0.00.00.1-0.0-0.3-0.2-0.2-0.20.10.10.10.10.10.2
Bone volume0.10.20.7-0.4-0.80.40.40.3-0.4-0.4-0.4-0.4-0.40.7
Breakpoint value in progressive ratio session2.23.928.5-5.3-3.2-0.6-0.7-0.60.70.70.70.70.7-0.6
Number of licking bursts0.51.43.3-1.8-1.61.11.11.0-1.0-1.0-1.0-1.0-1.00.9
Context. condit. distance diff. score0.10.11.21.10.40.10.10.1-0.1-0.1-0.1-0.1-0.10.3
Locomotion velocity, session 10.30.31.71.30.9-0.2-0.2-0.30.30.30.30.30.3-0.2
Locomotion distance, session 11.82.317.24.22.80.00.0-0.00.00.00.00.00.0-0.1
Locomotion velocity, session 20.91.07.32.72.00.00.0-0.0-0.0-0.0-0.0-0.0-0.0-0.2
Locomotion distance, session 22.33.322.74.83.4-0.3-0.3-0.50.40.40.40.40.4-0.5
Locomotion velocity, session 30.40.52.5-1.6-0.2-0.4-0.4-0.60.50.50.50.50.5-0.8
Locomotion distance, session 30.20.21.7-1.3-0.70.10.1-0.20.00.00.10.10.1-0.2
Stereotopy head waving bouts, day 31.31.611.2-3.4-2.4-0.3-0.3-0.30.30.30.30.30.3-0.1
Stereotopy head waving duration, day 31.21.59.9-3.1-2.50.10.10.2-0.1-0.1-0.1-0.1-0.10.3
Locomotion velocity, session 70.30.31.51.20.60.40.40.4-0.4-0.4-0.4-0.4-0.40.4
Locomotion distance, session 71.41.83.21.61.8-1.3-1.3-1.31.31.31.31.31.3-1.2
Stereotopy head waving bouts, day 73.23.824.0-4.9-3.31.01.00.8-0.9-0.9-0.9-0.9-0.90.6
Stereotopy head waving duration, day 73.64.525.7-5.1-3.51.31.31.0-1.2-1.2-1.1-1.2-1.10.9
Locomotion velocity, session 80.40.42.71.60.70.50.40.3-0.4-0.4-0.4-0.4-0.40.4
Locomotion distance, session 81.11.611.93.42.3-0.2-0.2-0.40.30.30.30.30.3-0.2
Degree of sensitization distance1.51.610.63.32.1-0.7-0.7-0.40.60.60.50.50.5-0.3
Degree of sensitization stereotypy3.74.119.0-4.4-2.91.61.61.4-1.5-1.5-1.5-1.5-1.50.9
Conditioned locomotion0.70.81.00.3-0.61.00.91.0-1.0-1.0-1.0-1.0-1.01.0
Cocaine response after cond. corrected0.30.40.9-0.80.4-0.7-0.7-0.60.60.60.60.60.6-1.0
Cocaine response after cond. not corrected0.60.81.4-1.00.4-0.9-0.9-0.90.90.90.90.90.9-1.2
Cocaine response before conditioning0.10.21.0-1.0-0.7-0.2-0.1-0.20.20.20.20.20.20.0
Saline control response0.81.22.11.31.4-1.1-1.0-1.01.01.01.01.01.0-0.9
Bone: connectivity density1.82.83.70.21.6-1.7-1.7-1.91.71.71.71.71.7-1.8
Bone: cortical apparent density2.23.525.15.03.3-0.5-0.5-0.50.50.50.50.50.5-0.4
Bone: cortical area1.01.612.93.61.6-0.7-0.7-0.40.50.50.50.50.50.1
Bone: cortical porosity2.12.317.2-4.1-2.1-0.7-0.7-0.50.60.60.60.60.6-0.7
Bone: cortical porosity1.31.47.5-2.7-1.3-0.9-0.9-0.80.90.90.80.90.8-0.8
Bone: cortical thickness3.86.336.16.03.8-1.5-1.5-1.41.41.51.41.41.4-0.9
Bone: cortical thickness4.04.96.42.52.0-2.3-2.3-2.22.22.22.22.22.2-1.6
Bone: cortical tissue density1.82.921.14.63.1-0.4-0.4-0.40.50.50.50.50.5-0.4
Condit. Reinf. active minus inactive responses0.40.50.60.5-0.10.70.70.7-0.7-0.7-0.7-0.7-0.70.7
Condit. Reinf. active-inactive response ratio0.50.60.7-0.0-0.50.80.80.8-0.8-0.8-0.8-0.8-0.80.8
Condit. Reinf. active responses1.31.710.23.21.40.80.80.8-0.8-0.8-0.8-0.8-0.80.9
Condit. Reinf. inactive responses1.72.313.63.71.50.90.91.0-1.0-1.0-1.0-1.0-1.01.1
Incentive salience index mean0.91.28.52.91.40.50.50.5-0.5-0.5-0.5-0.5-0.50.6
Condit. Reinf. lever presses1.52.319.14.42.4-0.1-0.1-0.10.10.10.10.10.10.2
Condit. Reinf. active minus inactive responses3.04.66.01.1-0.92.32.32.3-2.3-2.3-2.3-2.3-2.32.5
Condit. Reinf. active-inactive response ratio1.93.09.63.10.61.61.61.6-1.6-1.6-1.6-1.6-1.61.8
Condit. Reinf. active responses4.46.48.1-0.2-2.12.72.72.7-2.7-2.7-2.7-2.7-2.72.9
Condit. Reinf. inactive responses4.87.122.6-4.8-4.02.12.12.1-2.1-2.1-2.1-2.1-2.11.9
Condit. Reinf. lever presses2.23.16.1-1.1-2.51.71.71.7-1.7-1.7-1.7-1.7-1.72.1
Condit. Reinf. lever reinforcers received5.47.59.3-0.3-2.32.92.93.0-2.9-2.9-2.9-2.9-2.93.1
Conditioned reinforcement - actives0.10.40.50.2-0.30.70.70.6-0.7-0.7-0.7-0.7-0.70.7
Conditioned reinforcement - inactives0.00.10.50.70.7-0.0-0.00.10.00.00.00.00.0-0.0
Conditioned locomotion1.21.82.71.41.6-1.3-1.3-1.51.31.31.31.31.3-1.2
Patch foraging indifference point 0 sec0.61.74.52.11.5-1.3-1.3-1.21.21.21.21.21.2-0.8
Patch foraging indifference point AUC0.10.20.30.1-0.20.50.60.5-0.5-0.5-0.5-0.5-0.50.6
Delay disc. indifference point, 0s delay0.00.00.00.1-0.10.10.00.1-0.0-0.0-0.1-0.1-0.10.2
Delay disc. indifference point, 16s delay0.50.71.1-0.3-0.90.90.80.8-0.8-0.9-0.8-0.9-0.81.0
Delay disc. indifference point, 2s delay1.31.41.81.3-0.01.31.31.2-1.2-1.2-1.2-1.2-1.21.3
Delay disc. indifference point, 24s delay1.01.613.53.71.9-0.2-0.2-0.00.10.10.10.10.10.2
Delay disc. indifference point, 4s delay3.53.75.0-0.7-2.12.02.02.1-1.9-1.9-1.9-1.9-1.92.2
Delay disc. indifference point, 8s delay0.20.42.61.61.0-0.3-0.3-0.20.20.20.20.20.2-0.0
Indifference point function ln k0.72.25.02.22.1-1.3-1.3-1.31.31.31.31.31.3-1.3
Indifference point function log k0.72.25.02.22.1-1.3-1.3-1.31.31.31.31.31.3-1.3
Patch foraging total patch changes 0 sec0.51.32.01.41.1-1.2-1.3-1.21.11.11.11.11.1-0.8
Patch foraging total patch changes 12 sec0.10.10.80.9-0.1-0.3-0.3-0.10.10.10.10.10.10.2
Patch foraging total patch changes 18 sec0.61.51.91.20.11.21.31.2-1.3-1.3-1.3-1.3-1.31.4
Patch foraging total patch changes 24 sec0.30.91.10.91.1-1.0-1.0-1.00.90.90.90.90.9-0.8
Patch foraging total patch changes 6 sec0.50.83.5-1.9-1.60.50.50.5-0.5-0.5-0.5-0.5-0.50.6
Patch foraging time to switch 0 sec0.51.83.0-1.7-1.71.21.31.4-1.3-1.3-1.3-1.3-1.31.0
Patch foraging water rate 0 sec0.10.40.70.10.2-0.7-0.8-0.90.70.70.70.70.7-0.4
Patch foraging water rate 12 sec0.10.20.90.90.70.30.30.3-0.3-0.4-0.3-0.3-0.30.3
Patch foraging water rate 18 sec0.51.21.4-0.9-1.11.21.21.1-1.1-1.1-1.1-1.1-1.11.0
Patch foraging water rate 24 sec1.31.92.3-0.4-1.31.51.51.4-1.4-1.4-1.4-1.4-1.41.5
Patch foraging water rate 6 sec0.20.21.0-0.7-1.00.30.30.4-0.4-0.4-0.4-0.4-0.40.6
Seeking ratio, delayed vs. immediate footshock0.20.41.6-1.3-0.70.60.60.4-0.5-0.5-0.5-0.5-0.50.2
Distance traveled before self-admin0.00.00.1-0.20.1-0.1-0.1-0.30.20.20.20.20.2-0.3
Distance traveled after self-admin0.00.10.2-0.50.2-0.1-0.1-0.30.20.20.20.20.2-0.4
Extensor digitorum longus weight0.31.21.50.5-0.41.21.21.2-1.2-1.2-1.2-1.2-1.21.2
Bone: elastic displacement4.86.040.86.44.5-0.8-0.8-0.70.80.80.80.80.8-0.7
Bone: elastic work3.24.228.45.33.5-0.8-0.8-0.70.80.80.80.80.8-0.5
Bone: endosteal estimation0.71.810.5-3.2-2.70.40.40.5-0.4-0.4-0.4-0.4-0.40.6
Bone: endosteal perimeter2.46.014.7-2.9-3.82.12.12.3-2.1-2.1-2.1-2.1-2.12.5
Epididymis fat weight0.10.61.30.7-0.50.80.80.8-0.8-0.8-0.8-0.8-0.81.1
Delta time in closed arm before/after self-admin0.60.62.61.61.1-0.6-0.5-0.60.50.50.60.50.6-0.5
Delta time in open arm before/after self-admin0.80.92.0-1.4-0.2-0.8-1.0-1.11.01.01.01.01.0-0.9
Diff in mean of infusions in LGA sessions0.50.95.7-2.4-1.0-0.5-0.6-0.50.50.50.50.50.5-0.7
Delay discount exponential model param0.71.01.7-1.20.3-1.0-1.0-1.01.01.01.01.01.0-1.3
Extinction: sum of active levers before priming1.62.412.9-3.6-2.70.90.80.9-0.8-0.8-0.8-0.8-0.80.8
Active lever presses in extinction session 61.71.72.6-1.4-1.61.31.31.2-1.3-1.3-1.2-1.2-1.21.1
Bone: final force1.32.213.13.61.8-1.0-1.0-0.91.01.01.01.01.0-0.3
Bone: final moment1.93.020.14.52.4-1.0-1.0-0.91.01.00.91.01.0-0.3
Food consumed during 24 hour testing period1.01.92.6-0.40.0-1.6-1.6-1.51.61.61.61.61.6-1.1
Glucose1.21.92.21.11.3-1.4-1.4-1.51.41.41.41.41.4-1.3
Heart weight0.20.40.5-0.50.1-0.7-0.7-0.70.60.60.60.60.6-0.5
Delay discount hyperbolic model param0.70.91.6-1.10.3-1.0-0.9-1.00.90.90.91.01.0-1.3
Intermittent access intake day 1-15 change0.00.20.4-0.7-0.2-0.5-0.5-0.50.50.50.50.50.5-0.4
Intermittent access intake escalation0.10.53.5-1.9-1.3-0.2-0.2-0.20.20.10.10.10.10.0
Intermittent access intake escalation 20.50.82.3-1.5-1.40.70.70.6-0.7-0.7-0.7-0.7-0.70.8
Intermitt. access day 1 inactive lever presses0.22.84.51.02.1-1.6-1.6-1.61.71.71.71.71.7-1.9
Intermitt. access day 15 inactive lever presses0.84.14.81.42.2-2.1-2.1-2.02.12.12.12.12.1-2.0
Intermitt. access escalation Index0.82.63.30.20.9-1.8-1.8-1.71.81.81.81.81.8-1.7
Intermittent access day 1 total infusions0.20.63.61.91.00.50.50.5-0.5-0.5-0.5-0.5-0.50.5
Intermittent access day 15 total infusions0.00.00.1-0.1-0.30.00.00.1-0.1-0.1-0.1-0.1-0.10.3
Intermittent access terminal intake (last 3 days)0.50.81.20.6-0.30.90.90.9-0.9-1.0-1.0-1.0-1.01.1
Intermittent access total infusions0.30.42.51.60.70.40.40.3-0.4-0.4-0.4-0.4-0.40.5
Intermittent access day 1 locomotion1.22.22.60.91.5-1.5-1.5-1.61.51.51.51.51.5-1.4
Intermittent access day 15 total locomotion0.20.81.0-0.80.1-1.0-1.0-1.01.01.01.01.01.0-0.9
Intermittent access total locomotion0.30.40.6-0.40.1-0.7-0.7-0.80.70.70.70.70.7-0.5
Intermittent access standard deviation0.62.94.01.52.0-1.7-1.7-1.81.71.71.71.71.7-1.7
Left kidney weight0.00.10.80.90.1-0.2-0.2-0.30.20.20.20.20.20.3
Right kidney weight0.00.00.20.1-0.50.10.10.0-0.1-0.1-0.1-0.1-0.10.5
Cocaine induced anxiety1.23.43.71.11.7-1.9-1.9-1.91.91.91.91.91.9-1.8
Post-drug Anxiety1.11.21.5-0.10.7-1.2-1.2-1.21.21.21.21.21.2-1.1
Baseline Anxiety1.32.12.3-1.3-1.51.51.51.5-1.5-1.5-1.5-1.5-1.51.3
Tail length0.52.73.5-0.50.6-1.8-1.9-1.81.81.81.81.81.8-1.6
Length with tail2.29.911.42.03.0-3.4-3.4-3.33.33.33.33.33.3-3.0
Length without tail0.52.53.20.51.2-1.8-1.8-1.71.71.71.71.71.7-1.6
Times rat made contact with spout1.21.41.71.31.2-1.2-1.2-1.21.21.21.21.21.2-0.9
Lifetime Intake0.30.42.81.71.00.10.10.0-0.1-0.1-0.1-0.1-0.10.3
Liver weight, left0.20.40.60.70.2-0.8-0.8-0.60.70.70.70.70.7-0.3
Liver weight, right2.74.630.95.63.8-0.9-0.9-0.80.80.80.80.80.8-0.7
Locomotor activity0.20.31.41.20.8-0.3-0.4-0.50.40.40.40.40.4-0.2
Locomotor testing distance0.40.93.21.81.7-0.6-0.6-0.70.60.60.60.60.6-0.6
Locomotor testing rearing0.10.32.31.51.00.30.20.2-0.2-0.2-0.2-0.2-0.20.2
Locomotion in novel chamber2.22.94.0-0.40.3-1.9-2.0-1.91.91.91.91.91.9-1.6
Locomotion in novel chamber post-restriction0.10.20.7-0.4-0.8-0.4-0.4-0.30.30.30.30.30.30.1
Fecal boli incidents, locomotor time 10.10.20.50.50.7-0.4-0.4-0.60.40.40.40.40.4-0.5
Change in fecal boli incidents, locomotor task0.50.61.81.30.00.80.70.6-0.6-0.6-0.6-0.6-0.61.0
Time >=10cm from walls, locomotor time 10.00.00.00.10.1-0.0-0.0-0.00.10.10.10.10.10.0
Bouts of movement, locomotor time 10.60.81.5-0.3-1.20.70.70.9-0.9-0.9-0.9-0.9-0.91.2
Total resting periods, locomotor time 10.40.51.00.2-0.80.60.50.7-0.7-0.7-0.7-0.7-0.71.0
Rest time, locomotor task time 10.50.81.3-0.5-0.3-1.0-1.1-0.91.01.01.01.01.0-0.6
Distance moved, locomotor task time 10.00.10.50.40.7-0.3-0.2-0.30.30.30.30.30.3-0.4
Vertical activity count, locomotor time 10.00.30.70.50.8-0.5-0.4-0.50.60.60.60.60.6-0.6
Time >=10cm from walls, locomotor time 20.30.95.4-2.3-1.2-0.5-0.5-0.70.70.60.70.60.6-0.5
Bouts of movement, locomotor time 20.51.52.1-0.3-0.81.41.31.2-1.4-1.4-1.3-1.3-1.31.2
Total resting periods, locomotor time 20.51.92.60.3-0.51.61.51.4-1.6-1.5-1.5-1.5-1.51.3
Rest time, locomotor task time 20.71.12.11.40.11.10.91.1-1.1-1.1-1.1-1.1-1.11.2
Distance moved, locomotor task time 22.73.65.6-2.4-0.2-2.0-1.9-1.92.02.02.02.02.0-2.0
Vertical activity count, locomotor time 21.74.05.1-1.40.6-2.1-2.0-2.12.22.12.22.12.1-2.3
Light reinforcement 10.21.01.6-0.9-1.21.01.00.9-0.9-0.9-0.9-0.9-0.91.0
Light reinforcement 20.10.32.1-1.4-1.10.10.1-0.10.00.10.10.10.1-0.0
Bone: marrow area0.71.810.3-3.2-2.70.50.50.6-0.5-0.5-0.5-0.5-0.50.7
Bone: maximum diameter0.71.55.4-1.5-2.30.80.81.0-0.9-0.9-0.9-0.9-0.91.4
Bone: maximum force1.01.94.52.11.3-1.4-1.4-1.31.31.31.31.31.3-0.8
Bone: maximum moment1.32.58.73.01.8-1.4-1.4-1.31.41.31.31.31.3-0.8
Mean time between licks in bursts0.42.42.90.81.1-1.7-1.7-1.71.71.71.71.71.7-1.4
Mean num. licks in bursts1.64.37.82.82.5-2.0-2.0-2.01.91.91.91.91.9-1.6
Cd content in liver0.30.30.8-0.9-0.0-0.5-0.5-0.50.50.50.50.50.5-0.7
Co content in liver0.30.30.40.6-0.10.60.60.7-0.6-0.6-0.6-0.6-0.60.6
Cu content in liver5.46.416.1-3.5-4.02.12.12.1-2.1-2.1-2.1-2.1-2.12.4
Fe content in liver0.30.31.7-1.3-1.30.10.10.1-0.1-0.1-0.1-0.1-0.10.4
K content in liver2.42.43.0-0.6-1.61.61.61.6-1.6-1.6-1.6-1.6-1.61.7
Mg content in liver1.01.11.80.8-0.61.11.11.1-1.1-1.0-1.1-1.1-1.11.3
Mn content in liver0.30.31.5-1.2-0.80.50.50.5-0.4-0.4-0.4-0.4-0.40.2
Na content in liver1.41.63.81.90.31.21.21.2-1.2-1.2-1.2-1.2-1.21.4
Rb content in liver2.83.39.2-3.0-2.91.41.41.4-1.4-1.4-1.4-1.4-1.41.4
Se content in liver0.60.85.6-2.4-1.60.10.10.1-0.1-0.1-0.1-0.1-0.10.2
Sr content in liver2.62.32.5-0.8-1.31.61.61.6-1.6-1.6-1.6-1.6-1.61.5
Zn content in liver0.40.51.71.30.9-0.6-0.6-0.50.60.60.50.50.5-0.4
Bone: minimum diameter0.00.10.40.6-0.1-0.3-0.3-0.20.30.30.20.30.30.1
Time in familiar zone, hab. session 11.51.712.7-3.6-2.40.10.10.0-0.1-0.1-0.0-0.1-0.00.1
Time in novel zone, hab. session 11.01.16.72.61.60.60.60.6-0.6-0.6-0.6-0.6-0.60.4
Total zone transitions, hab. session 10.30.42.31.51.20.20.20.3-0.2-0.2-0.2-0.2-0.2-0.0
Total locomotion distance, hab. session 11.21.62.61.60.61.31.31.3-1.3-1.3-1.3-1.3-1.31.1
Locomotion velocity, hab. session 11.42.02.81.70.41.51.41.4-1.5-1.5-1.5-1.5-1.51.3
Time in familiar zone, hab. session 20.30.43.0-1.7-0.90.20.20.1-0.1-0.1-0.1-0.1-0.1-0.0
Time in novel zone, hab. session 20.80.81.4-0.5-1.20.80.81.0-0.9-0.9-0.9-0.9-0.91.1
Total zone transitions, hab. session 20.81.07.62.81.90.10.1-0.0-0.0-0.0-0.0-0.0-0.0-0.0
Total locomotion distance, hab. session 21.21.511.43.42.20.30.30.2-0.2-0.2-0.2-0.2-0.20.2
Locomotion velocity, hab. session 22.33.123.84.93.20.20.20.1-0.1-0.1-0.1-0.1-0.10.0
Novel to familiar place preference ratio1.21.59.4-3.1-2.2-0.6-0.6-0.50.60.60.50.60.6-0.2
Novelty place preference1.41.812.2-3.5-2.5-0.4-0.4-0.30.40.40.40.40.4-0.0
Time in novel zone, NPP test1.82.215.1-3.9-3.0-0.3-0.3-0.20.20.20.20.20.20.1
Total zone transitions, NPP test2.03.017.54.23.3-0.5-0.6-0.80.70.70.70.70.7-0.7
Total locomotion distance, NPP test0.91.36.52.62.10.80.80.5-0.6-0.6-0.6-0.6-0.60.1
Locomotion velocity, NPP test0.91.37.22.72.20.60.60.4-0.5-0.5-0.5-0.5-0.50.0
Intraocular pressure2.43.94.91.80.12.22.22.1-2.1-2.1-2.1-2.1-2.12.0
Delta distance traveled before/after self-admin0.40.50.6-0.3-0.30.70.80.7-0.7-0.8-0.7-0.7-0.70.6
Delta ambulatory time before/after self-admin0.50.91.20.30.01.11.11.0-1.0-1.0-1.0-1.0-1.00.8
Parametrial fat weight1.33.15.42.32.2-1.7-1.7-1.61.71.71.71.71.7-1.4
Pavlov. Cond. lever latency3.34.222.6-4.8-3.21.31.31.1-1.2-1.3-1.2-1.2-1.20.8
Pavlov. Cond. magazine entry latency2.02.612.33.51.51.21.21.3-1.2-1.2-1.2-1.2-1.21.2
Pavlov. Cond. change in total contacts3.53.826.95.23.3-0.8-0.7-0.60.70.70.70.70.7-0.4
Pavlov. Cond. index score2.93.729.25.43.3-0.3-0.3-0.10.30.30.20.30.3-0.0
Pavlov. Cond. latency score2.53.223.44.83.1-0.6-0.6-0.40.50.50.50.50.5-0.3
Pavlov. Cond. lever contacts5.76.843.66.64.4-1.2-1.2-1.11.21.21.21.21.2-0.8
Pavlov. Cond. magazine entry number1.62.010.9-3.3-1.4-0.9-1.0-1.11.01.01.01.01.0-1.0
Pavlov. Cond. intertrial magazine entries0.70.86.0-2.4-1.8-0.1-0.10.00.00.00.00.00.00.1
Pavlov. Cond. lever-magazine prob. diff.3.54.434.75.93.6-0.3-0.3-0.10.20.20.20.20.2-0.0
Pavlov. Cond. response bias3.24.033.15.83.10.30.30.4-0.3-0.3-0.4-0.4-0.40.6
Pavlov. Cond. lever latency0.71.01.70.31.3-1.0-1.0-1.01.01.01.01.01.0-1.3
Pavlov. Cond. magazine entry latency0.30.41.5-1.1-1.20.40.40.4-0.4-0.4-0.4-0.4-0.40.6
Pavlov. Cond. change in total contacts0.61.52.61.6-0.51.21.21.2-1.2-1.2-1.2-1.2-1.21.6
Pavlov. Cond. index score0.71.11.90.2-1.01.11.11.1-1.1-1.1-1.1-1.1-1.11.4
Pavlov. Cond. latency score0.71.11.8-0.5-1.31.01.01.0-1.0-1.0-1.0-1.0-1.01.3
Pavlov. Cond. lever contacts0.60.91.5-0.2-1.20.90.90.9-0.9-0.9-0.9-0.9-0.91.2
Pavlov. Cond. magazine entry number0.60.71.1-0.20.7-0.9-0.9-0.90.90.90.90.90.9-1.1
Pavlov. Cond. intertrial magazine entries0.51.15.7-2.4-1.60.70.70.7-0.7-0.7-0.7-0.7-0.70.6
Pavlov. Cond. lever-magazine prob. diff.0.91.42.50.6-0.91.31.31.2-1.2-1.2-1.2-1.2-1.21.6
Pavlov. Cond. response bias0.91.22.10.6-0.81.11.11.1-1.1-1.1-1.1-1.1-1.11.4
Time in closed arm before self-admin6.310.913.3-0.7-2.33.63.53.5-3.6-3.6-3.6-3.6-3.63.4
Time in closed arm after self-admin10.111.513.0-1.3-3.03.63.63.6-3.6-3.6-3.6-3.6-3.63.5
Time in open arm before self-admin1.51.82.4-0.20.2-1.6-1.5-1.41.51.51.51.51.5-1.3
Time in open arm after self-admin6.47.18.50.11.7-2.9-2.9-2.92.92.92.92.92.9-2.8
Bone: periosteal estimation0.00.10.80.0-0.9-0.1-0.10.20.00.0-0.0-0.0-0.00.5
Bone: periosteal perimeter0.91.83.40.7-1.21.21.21.5-1.3-1.3-1.3-1.3-1.31.8
Bone: post-yield work2.23.722.7-4.8-2.4-1.1-1.1-1.21.21.21.21.21.2-1.1
Progressive ratio test 1 active lever presses0.40.74.52.10.90.40.40.3-0.4-0.5-0.5-0.5-0.50.7
Progressive ratio test 1 breakpoint0.40.64.62.11.00.40.40.2-0.4-0.4-0.4-0.4-0.40.6
Progressive ratio test 1 inactive lever presses0.10.31.51.21.2-0.2-0.2-0.40.20.20.20.20.2-0.3
Progressive ratio test 2 active lever presses0.10.21.11.10.40.20.20.2-0.2-0.3-0.3-0.3-0.30.4
Progressive ratio test 2 breakpoint0.20.31.11.00.30.40.40.3-0.4-0.4-0.4-0.4-0.40.5
Progressive ratio test 2 inactive lever presses0.00.10.1-0.10.2-0.3-0.3-0.40.30.30.30.30.3-0.3
Incentive Sensitization - Responses0.00.10.3-0.6-0.2-0.2-0.2-0.20.20.20.20.20.2-0.2
Incentive Sensitization - Breakpoint0.00.10.5-0.7-0.5-0.0-0.00.00.10.10.00.10.1-0.0
Sum of active levers in priming session hrs 5-62.42.26.8-2.6-2.41.11.21.1-1.1-1.1-1.1-1.1-1.11.2
Progressive ratio0.20.72.61.61.4-0.5-0.5-0.50.60.60.60.60.6-0.8
Food seeking constrained by brief footshock1.11.37.52.71.10.80.80.7-0.8-0.8-0.8-0.8-0.80.8
Seeking ratio, punishment vs. effort0.61.21.9-1.0-1.41.01.01.0-1.1-1.1-1.1-1.1-1.11.3
Retroperitoneal fat weight0.20.81.60.4-0.70.90.90.9-0.9-0.9-0.9-0.9-0.91.3
Reaction time number correct0.00.10.20.20.10.40.40.3-0.4-0.4-0.4-0.4-0.40.3
Reaction time mean minus median0.10.53.61.91.4-0.1-0.10.10.00.00.00.00.0-0.1
Reaction time mean minus median AUC0.21.410.63.22.2-0.1-0.00.2-0.1-0.1-0.1-0.1-0.1-0.0
Reaction time num false alarms0.20.31.7-1.3-1.0-0.1-0.1-0.10.20.20.20.20.2-0.0
Reaction time num false alarms AUC0.20.40.5-0.30.0-0.6-0.7-0.70.70.70.70.70.7-0.6
Reaction time trials correct on left0.00.10.20.20.10.40.40.3-0.4-0.4-0.4-0.4-0.40.3
Reaction time trials on left0.00.10.10.30.20.40.40.2-0.3-0.4-0.4-0.4-0.40.3
Reaction time mean0.92.115.64.02.20.40.40.8-0.6-0.5-0.6-0.6-0.60.5
Reaction time mean AUC0.71.610.63.31.80.50.50.8-0.7-0.6-0.7-0.7-0.70.5
Median of all reaction times1.21.911.43.41.50.70.71.1-0.9-0.9-0.9-0.9-0.90.9
Reaction time omissions0.50.82.31.50.8-0.9-0.9-0.80.90.90.80.90.8-0.3
Reaction time false alarm rate0.40.60.90.90.7-0.7-0.8-0.70.80.80.80.80.8-0.7
Reaction time premature initiation rate0.20.31.31.21.1-0.2-0.1-0.20.30.30.20.30.2-0.4
Reaction time premature initiations0.10.41.51.11.2-0.3-0.3-0.40.40.40.40.40.4-0.5
Std. dev. reaction times1.03.321.24.63.3-0.9-0.8-0.50.70.70.70.70.7-0.7
Reaction time trials completed0.00.10.10.30.20.40.40.2-0.3-0.4-0.4-0.4-0.40.3
Reaction time trials AUC0.00.10.40.70.50.30.20.1-0.2-0.2-0.2-0.2-0.20.2
Run reversals in cocaine runway, females1.71.93.71.91.7-1.3-1.2-1.21.31.31.31.31.3-1.2
Run reversals in cocaine runway, males0.50.54.22.11.30.0-0.10.0-0.0-0.0-0.0-0.0-0.00.0
Latency to leave start box in cocaine runway0.70.91.5-1.2-1.20.91.00.8-0.9-0.9-0.9-0.9-0.90.8
Latency to leave start box in cocaine runway, F0.10.10.60.70.50.10.30.0-0.1-0.2-0.1-0.1-0.10.1
Latency to leave start box in cocaine runway, M1.31.32.8-1.7-1.61.01.01.0-1.0-1.0-1.0-1.0-1.01.0
Std. dev. time between licks in bursts1.01.913.9-3.7-2.6-0.1-0.1-0.20.20.20.20.20.2-0.0
Total sessions with >9 infusions0.10.20.80.90.40.30.30.1-0.3-0.3-0.3-0.3-0.30.5
Short access day 1 total inactive lever presses0.20.53.61.91.30.00.0-0.1-0.0-0.0-0.0-0.0-0.00.1
Short access day 10 total inactive lever presses1.06.68.50.32.1-2.7-2.7-2.82.72.72.72.72.7-2.9
Short access day 1 total infusions0.00.10.70.80.6-0.0-0.0-0.20.00.00.00.00.00.1
Short access day 10 total infusions0.10.10.80.90.70.20.20.1-0.1-0.1-0.1-0.1-0.10.1
Short access total infusions0.30.42.81.71.2-0.1-0.1-0.30.10.10.10.10.10.1
Short access day 1 locomotion0.10.21.5-1.2-0.6-0.2-0.2-0.30.20.20.20.20.2-0.2
Short access day 10 total locomotion0.31.41.7-0.90.2-1.3-1.3-1.31.31.21.21.21.2-1.2
Short access total locomotion0.20.40.6-0.30.2-0.7-0.7-0.80.70.60.60.60.6-0.6
One hour access (0.3 mA shock)0.10.10.10.40.10.20.20.3-0.2-0.2-0.3-0.3-0.30.3
Compulsive drug intake0.50.81.60.61.2-0.8-0.8-0.90.80.80.80.80.8-1.0
One hour access (shock baseline)0.00.10.20.2-0.30.30.30.3-0.3-0.3-0.3-0.3-0.30.5
Social response proportion3.24.18.2-2.0-2.91.91.81.9-1.9-1.9-1.9-1.9-1.92.2
Social responses1.01.32.3-0.8-1.51.21.11.0-1.0-1.0-1.1-1.0-1.01.4
Social time1.52.42.9-0.9-1.61.71.71.5-1.6-1.6-1.6-1.6-1.61.6
Soleus weight0.41.14.52.11.6-0.8-0.8-0.80.80.80.80.80.8-0.6
Bone: stiffness0.40.84.4-2.1-2.0-0.2-0.2-0.20.20.20.10.20.10.3
Tibialis anterior weight0.51.61.9-1.3-1.21.41.41.2-1.3-1.3-1.3-1.3-1.31.1
Time to tail flick, vehicle, before self-admin1.31.610.6-3.3-2.1-0.6-0.5-0.40.50.50.50.50.5-0.4
Time to tail flick, vehicle, after self-admin1.22.53.0-0.5-1.41.71.61.7-1.7-1.7-1.7-1.7-1.71.7
Time to tail flick, test, before self-admin2.22.63.2-0.0-1.21.71.71.7-1.7-1.7-1.7-1.7-1.71.8
Time to tail flick, test, after self-admin0.91.05.42.31.10.60.70.7-0.7-0.7-0.7-0.7-0.70.5
Delta time to tail flick, vehicle, before/after SA1.21.24.62.10.81.00.91.0-1.0-1.0-1.0-1.0-1.00.9
Delta time to tail flick, test, before/after SA0.91.14.02.02.0-0.7-0.7-0.70.70.70.70.70.7-0.8
Tibia length1.33.512.53.52.6-1.6-1.6-1.51.51.51.51.51.5-1.1
Ambulatory time before self-admin0.10.42.6-1.6-1.0-0.1-0.2-0.20.20.20.20.20.2-0.2
Ambulatory time after self-admin0.10.10.7-0.8-0.20.20.2-0.0-0.1-0.1-0.1-0.1-0.1-0.1
Bone: tissue strength0.60.65.12.31.00.20.20.2-0.1-0.1-0.2-0.1-0.10.4
Total heroin consumption1.31.512.3-3.5-2.10.20.20.0-0.0-0.0-0.0-0.0-0.0-0.1
Bone: trabecular number0.61.11.70.51.1-1.0-1.0-1.31.11.11.11.11.1-1.0
Bone: trabecular spacing0.00.00.10.20.20.00.00.2-0.1-0.1-0.1-0.1-0.1-0.1
Bone: trabecular thickness0.10.20.3-0.3-0.3-0.4-0.4-0.60.50.50.50.50.5-0.1
Bone: trabecular tissue density0.10.21.51.20.1-0.1-0.10.10.10.10.00.10.10.4
Water consumed over 24 hours0.00.00.1-0.10.3-0.2-0.2-0.20.20.20.20.20.2-0.3
Number of responses in last shaping day0.50.71.3-0.5-1.10.80.80.6-0.8-0.8-0.8-0.8-0.81.0