Hub : Genes

Serping1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Serping1 0.1 0.07 1.8e-13 0.11 0.11 0.12 0.12 4.3e-12 6.2e-12 2.4e-13 9.4e-13
2 OFC gene expression Serping1 0.38 0.22 4.7e-06 0.15 0.15 0.14 0.15 1.7e-04 2.0e-04 4.4e-04 2.2e-04
3 IL gene expression Serping1 0.18 0.16 2.8e-03 0.09 0.08 0.09 0.09 3.9e-03 4.9e-03 3.4e-03 4.0e-03
4 pVTA alternative TSS NM_199093.2 0.05 0.04 1.8e-04 0.04 0.04 0.04 0.04 1.5e-04 1.9e-04 3.3e-04 1.4e-04
5 pVTA alternative TSS XM_006234447.4 0.05 0.04 1.5e-04 0.04 0.04 0.04 0.05 1.9e-04 1.6e-04 1.8e-04 1.4e-04
6 NAcc alternative TSS NM_199093.2 0.02 0.02 9.2e-04 0.01 0.02 0.02 0.01 2.5e-03 9.8e-04 1.5e-03 2.0e-03
7 IC gene expression Serping1 0.21 0.14 8.3e-08 0.18 0.15 0.16 0.16 6.3e-08 6.3e-07 3.3e-07 2.8e-07
8 Liver isoform ratio XM_006234447.4 0.4 0.2 0.0e+00 0.27 0.28 0.28 0.28 2.4e-30 5.0e-31 6.4e-31 4.0e-31
9 Liver isoform ratio NM_199093.2 0.43 0.2 0.0e+00 0.28 0.28 0.28 0.29 5.0e-31 1.1e-31 1.4e-31 6.7e-32
10 NAcc isoform ratio NM_199093.2 0.01 0.01 4.0e-03 0.01 0.01 0.01 0.01 5.5e-03 3.0e-03 1.1e-02 6.5e-03
11 Brain isoform ratio XM_006234447.4 0.07 0.06 3.7e-06 0.06 0.06 0.06 0.05 6.6e-06 4.3e-06 4.8e-06 8.3e-06
12 Brain isoform ratio NM_199093.2 0.07 0.06 4.3e-06 0.05 0.06 0.06 0.05 8.1e-06 5.3e-06 6.6e-06 9.9e-06
13 NAcc isoform ratio XM_006234447.4 0.02 0.01 2.0e-03 0.01 0.02 0.01 0.01 3.1e-03 1.4e-03 4.8e-03 3.3e-03
14 Brain alternative TSS XM_006234447.4 0.15 0.12 4.1e-13 0.13 0.13 0.13 0.13 3.6e-12 1.9e-12 2.1e-12 2.2e-12
15 Brain alternative TSS NM_199093.2 0.15 0.13 4.1e-13 0.13 0.13 0.13 0.13 3.6e-12 1.9e-12 2.2e-12 2.3e-12
16 Liver mRNA stability Serping1 0.06 0.05 1.3e-07 0.04 0.06 0.05 0.05 1.1e-05 8.5e-07 2.0e-06 2.2e-06
17 NAcc gene expression Serping1 0.04 0.03 3.9e-08 0.04 0.05 0.04 0.04 4.6e-07 5.3e-08 2.6e-07 5.6e-07
18 pVTA gene expression Serping1 0.42 0.24 0.0e+00 0.38 0.38 0.38 0.39 1.1e-31 1.7e-32 1.3e-32 6.7e-33
19 Liver gene expression Serping1 0.4 0.15 0.0e+00 0.41 0.43 0.43 0.43 3.8e-48 1.2e-52 1.1e-51 9.9e-52
20 Brain intron excision ratio chr3_90258687_90259185 0.07 0.07 3.7e-06 0.06 0.06 0.05 0.06 4.3e-06 3.9e-06 2.6e-05 6.3e-06
21 PL gene expression Serping1 0.17 0.11 0.0e+00 0.21 0.22 0.21 0.21 1.1e-22 4.8e-23 1.5e-22 1.1e-22
22 Brain gene expression Serping1 0.26 0.17 0.0e+00 0.21 0.23 0.22 0.22 1.1e-19 5.9e-21 2.9e-20 5.4e-20
23 Liver intron excision ratio chr3_90258687_90259185 0.44 0.21 0.0e+00 0.24 0.24 0.24 0.24 1.4e-26 1.1e-26 1.2e-26 7.7e-27
24 Liver alternative TSS XM_006234447.4 0.66 0.12 0.0e+00 0.52 0.56 0.56 0.56 1.2e-67 2.7e-74 5.2e-74 1.1e-74
25 Adipose gene expression Serping1 0.45 0.14 0.0e+00 0.5 0.51 0.51 0.52 3.3e-63 4.8e-66 1.1e-64 2.5e-66
26 Liver alternative TSS NM_199093.2 0.7 0.11 0.0e+00 0.52 0.55 0.55 0.55 2.4e-66 9.3e-74 4.0e-73 7.9e-74

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.50.91.9-0.3-1.4-1.2-1.01.0-1.1-1.00.8-0.8-1.01.0-1.01.01.0-1.01.01.01.01.01.00.91.00.80.80.8-0.8
Area under the delay curve2.23.44.4-0.51.72.01.8-1.81.81.8-2.12.11.8-1.81.8-1.8-1.81.8-1.8-1.8-1.9-1.8-1.8-1.8-1.8-2.1-2.0-2.02.1
BMI with tail0.41.51.8-0.3-1.3-1.1-1.11.1-1.3-1.01.3-1.3-1.31.3-1.31.31.3-1.31.31.31.11.31.31.31.31.31.31.3-1.3
BMI without tail0.21.27.22.70.80.80.9-0.91.01.3-0.90.91.0-1.01.0-1.0-1.01.0-1.0-1.0-1.1-1.0-1.0-1.0-1.0-1.1-1.1-1.11.1
Body weight0.41.64.62.1-1.3-1.5-1.31.3-1.2-1.01.2-1.2-1.21.2-1.21.21.2-1.21.21.21.11.21.21.21.21.21.31.2-1.2
Weight adjusted by age0.10.45.82.4-0.5-0.5-0.50.4-0.3-0.40.8-0.8-0.20.3-0.30.20.2-0.20.20.30.40.20.20.30.20.30.20.2-0.2
Bone surface2.65.16.41.1-2.5-2.4-2.32.3-2.3-2.32.2-2.2-2.32.3-2.32.32.3-2.32.32.32.32.32.32.32.32.12.12.1-2.1
Bone volume2.44.76.20.9-2.5-2.3-2.32.2-2.3-2.22.1-2.1-2.22.3-2.22.22.2-2.22.22.22.22.22.22.22.22.12.12.1-2.0
Breakpoint value in progressive ratio session0.30.51.0-0.1-0.7-1.0-0.60.7-0.7-0.80.6-0.6-0.70.7-0.70.70.7-0.70.70.70.90.70.70.70.70.70.70.7-0.7
Number of licking bursts0.92.611.13.3-1.5-1.7-1.81.8-1.5-1.41.5-1.5-1.51.5-1.51.51.5-1.51.51.51.51.51.51.51.51.51.51.4-1.4
Context. condit. distance diff. score0.50.60.8-0.5-0.9-0.6-0.50.6-0.8-0.60.8-0.8-0.80.8-0.80.80.8-0.80.80.80.70.80.80.80.80.80.80.8-0.8
Locomotion velocity, session 13.43.84.31.7-1.9-2.0-2.12.1-2.0-1.81.9-1.9-2.02.0-2.02.02.0-2.02.02.02.02.02.02.02.02.02.01.9-1.9
Locomotion distance, session 10.20.21.61.2-0.3-0.4-0.50.4-0.4-0.50.4-0.4-0.40.4-0.40.40.4-0.40.40.40.50.40.40.40.40.40.40.4-0.4
Locomotion velocity, session 20.60.70.9-0.3-0.9-0.8-0.90.9-0.9-0.90.8-0.8-0.90.9-0.90.90.9-0.90.90.90.80.90.80.90.90.80.80.8-0.8
Locomotion distance, session 20.50.71.0-0.31.01.00.8-0.80.90.8-0.80.80.9-0.80.8-0.9-0.80.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.9-0.90.9
Locomotion velocity, session 30.60.60.8-0.40.80.80.9-0.90.80.7-0.80.80.8-0.80.8-0.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.80.8
Locomotion distance, session 30.60.61.1-0.10.60.60.7-0.70.80.5-0.90.90.8-0.80.8-0.8-0.80.8-0.8-0.8-0.7-0.8-0.8-0.8-0.8-1.0-1.0-1.01.1
Stereotopy head waving bouts, day 30.81.01.10.2-1.0-0.9-0.90.9-1.0-0.91.0-1.0-1.01.0-1.01.01.0-1.01.01.00.91.01.01.01.01.01.01.0-1.0
Stereotopy head waving duration, day 31.11.31.80.3-1.1-1.0-1.01.0-1.1-1.01.2-1.2-1.21.2-1.21.21.2-1.21.21.21.11.21.21.21.21.31.31.3-1.3
Locomotion velocity, session 71.41.62.4-1.51.31.41.6-1.51.21.3-1.21.21.2-1.21.2-1.2-1.21.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.21.2
Locomotion distance, session 76.88.710.0-2.62.83.13.2-3.12.93.1-2.92.92.9-2.92.9-2.9-2.92.9-2.9-2.9-3.1-2.9-2.9-3.0-2.9-2.9-2.9-2.92.9
Stereotopy head waving bouts, day 72.73.23.50.4-1.9-1.8-1.81.8-1.9-1.81.7-1.7-1.91.9-1.91.91.8-1.81.91.91.81.91.91.91.91.71.71.7-1.7
Stereotopy head waving duration, day 73.13.84.3-0.6-2.0-1.9-1.91.9-2.1-1.91.9-1.9-2.12.0-2.02.12.0-2.02.12.02.02.02.02.02.11.91.91.9-1.8
Locomotion velocity, session 80.40.50.70.00.70.80.8-0.80.70.8-0.70.70.7-0.70.7-0.7-0.70.7-0.7-0.7-0.8-0.7-0.7-0.7-0.7-0.7-0.7-0.70.7
Locomotion distance, session 80.30.50.9-0.70.70.90.9-0.90.70.8-0.60.60.7-0.70.7-0.7-0.70.7-0.7-0.7-0.8-0.7-0.7-0.7-0.7-0.6-0.7-0.60.6
Degree of sensitization distance0.60.75.2-2.30.81.11.0-1.00.71.0-0.60.60.7-0.70.7-0.7-0.70.7-0.7-0.7-0.8-0.7-0.7-0.7-0.7-0.5-0.5-0.50.4
Degree of sensitization stereotypy2.02.22.70.7-1.6-1.5-1.71.6-1.6-1.41.4-1.4-1.61.6-1.61.61.6-1.61.61.61.51.61.61.61.61.41.41.4-1.3
Conditioned locomotion3.33.84.72.1-1.9-2.2-2.12.1-1.9-2.12.0-2.0-1.91.9-1.91.91.9-1.91.91.92.01.91.91.91.91.91.91.8-1.8
Cocaine response after cond. corrected0.10.21.21.10.70.30.4-0.40.50.4-0.40.40.4-0.40.4-0.4-0.40.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.40.3
Cocaine response after cond. not corrected0.20.30.70.80.80.50.5-0.50.60.5-0.60.60.6-0.60.6-0.6-0.60.6-0.6-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.50.5
Cocaine response before conditioning0.10.10.4-0.6-0.4-0.2-0.30.3-0.3-0.20.1-0.1-0.30.3-0.30.30.2-0.20.30.20.20.20.20.20.20.20.20.2-0.2
Saline control response0.40.60.90.5-0.8-0.9-0.80.8-0.8-0.90.8-0.8-0.80.8-0.80.80.8-0.80.80.80.90.80.80.90.80.70.70.7-0.6
Bone: connectivity density0.40.61.20.0-1.1-1.0-0.80.8-0.8-0.90.6-0.6-0.80.8-0.80.80.8-0.70.80.70.80.70.70.70.70.60.70.7-0.6
Bone: cortical apparent density0.10.10.2-0.3-0.3-0.4-0.20.3-0.3-0.40.2-0.2-0.30.3-0.30.30.3-0.30.30.30.30.30.30.30.30.20.20.2-0.2
Bone: cortical area0.00.00.10.3-0.2-0.1-0.10.1-0.2-0.00.2-0.2-0.20.2-0.20.20.2-0.20.20.20.10.20.20.20.20.00.0-0.00.0
Bone: cortical porosity0.10.10.3-0.50.30.20.3-0.30.20.2-0.20.20.2-0.20.2-0.2-0.20.2-0.2-0.2-0.2-0.3-0.2-0.2-0.2-0.2-0.2-0.20.2
Bone: cortical porosity0.40.40.6-0.10.70.70.7-0.70.70.7-0.70.70.7-0.70.7-0.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.6-0.6-0.60.6
Bone: cortical thickness0.30.50.70.10.70.70.7-0.70.70.7-0.60.60.7-0.60.6-0.7-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.8-0.8-0.80.9
Bone: cortical thickness0.70.91.51.11.21.11.0-1.01.01.2-0.80.80.9-0.90.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.90.9
Bone: cortical tissue density0.00.00.1-0.4-0.2-0.3-0.20.2-0.2-0.30.1-0.1-0.20.2-0.20.20.2-0.20.20.20.20.20.20.20.20.10.10.1-0.1
Condit. Reinf. active minus inactive responses0.00.00.1-0.30.10.40.2-0.20.10.2-0.10.10.1-0.10.1-0.1-0.10.1-0.1-0.1-0.2-0.1-0.1-0.1-0.1-0.2-0.2-0.20.2
Condit. Reinf. active-inactive response ratio0.00.00.2-0.4-0.1-0.1-0.10.1-0.1-0.10.0-0.0-0.10.1-0.10.10.1-0.10.10.10.10.10.10.10.10.10.10.1-0.1
Condit. Reinf. active responses0.10.20.4-0.20.40.60.4-0.40.40.5-0.40.40.4-0.40.4-0.4-0.40.4-0.4-0.4-0.5-0.4-0.4-0.4-0.4-0.5-0.5-0.50.5
Condit. Reinf. inactive responses0.30.40.80.20.60.90.7-0.70.60.8-0.60.60.6-0.60.6-0.6-0.60.6-0.6-0.6-0.7-0.6-0.6-0.6-0.6-0.7-0.7-0.70.7
Incentive salience index mean0.10.10.20.4-0.4-0.2-0.40.4-0.3-0.30.4-0.4-0.30.3-0.30.30.3-0.30.30.40.30.30.40.30.30.30.30.3-0.2
Condit. Reinf. lever presses0.00.00.90.9-0.1-0.0-0.20.2-0.0-0.10.1-0.0-0.00.0-0.00.00.0-0.00.00.00.00.00.00.00.0-0.1-0.1-0.10.1
Condit. Reinf. active minus inactive responses0.50.70.90.3-0.8-0.8-0.90.9-0.9-0.90.8-0.8-0.90.9-0.90.90.9-0.90.90.90.90.90.90.90.90.80.80.8-0.8
Condit. Reinf. active-inactive response ratio0.20.22.01.4-0.3-0.4-0.40.4-0.4-0.50.5-0.5-0.40.4-0.40.40.4-0.40.40.40.50.40.40.40.40.40.40.4-0.4
Condit. Reinf. active responses1.01.51.8-1.1-1.3-1.1-1.21.2-1.3-1.31.1-1.1-1.31.2-1.21.31.2-1.21.21.21.31.21.21.21.21.11.11.2-1.1
Condit. Reinf. inactive responses0.91.35.5-2.4-1.2-0.9-1.01.0-1.2-1.20.9-1.0-1.11.1-1.11.11.1-1.11.11.11.11.11.11.11.11.01.01.0-1.0
Condit. Reinf. lever presses0.40.63.5-1.9-0.9-0.5-0.60.6-0.8-0.80.6-0.6-0.70.7-0.70.70.7-0.70.70.70.60.70.70.70.70.60.60.6-0.6
Condit. Reinf. lever reinforcers received1.01.42.7-1.6-1.2-1.0-1.11.1-1.2-1.31.0-1.0-1.21.2-1.21.21.2-1.21.21.21.21.21.21.21.21.01.11.1-1.0
Conditioned reinforcement - actives0.41.72.81.1-1.0-0.5-1.01.1-1.2-0.91.7-1.7-1.31.3-1.31.31.3-1.31.31.41.11.31.41.41.41.51.41.4-1.4
Conditioned reinforcement - inactives0.61.72.4-0.1-1.5-0.7-1.31.3-1.4-1.31.3-1.3-1.41.4-1.41.41.4-1.41.41.41.41.41.41.41.41.31.21.3-1.2
Conditioned locomotion0.10.20.70.8-0.30.3-0.20.3-0.4-0.30.3-0.3-0.40.4-0.40.40.5-0.50.50.50.20.50.50.50.50.40.50.5-0.5
Patch foraging indifference point 0 sec0.20.61.5-1.20.70.40.6-0.70.70.9-0.90.90.8-0.80.8-0.8-0.80.8-0.8-0.8-0.9-0.8-0.8-0.9-0.8-0.8-0.7-0.70.7
Patch foraging indifference point AUC0.20.44.02.0-0.3-0.5-0.40.5-0.4-0.40.6-0.6-0.50.5-0.50.50.5-0.50.50.50.50.50.50.50.50.60.60.6-0.7
Delay disc. indifference point, 0s delay2.93.34.3-1.31.71.91.8-1.81.71.7-1.91.91.8-1.81.8-1.8-1.81.8-1.8-1.8-1.8-1.8-1.8-1.8-1.8-2.0-2.1-2.02.1
Delay disc. indifference point, 16s delay0.20.20.8-0.90.20.60.6-0.60.40.6-0.40.40.4-0.40.4-0.4-0.40.4-0.4-0.4-0.5-0.4-0.4-0.4-0.4-0.5-0.5-0.50.6
Delay disc. indifference point, 2s delay0.91.02.0-0.80.91.41.0-1.00.90.9-1.11.10.9-0.90.9-0.9-0.90.9-0.9-0.9-1.1-0.9-0.9-1.0-0.9-1.1-1.1-1.11.1
Delay disc. indifference point, 24s delay0.20.35.72.4-0.3-0.5-0.50.4-0.00.0-0.10.10.1-0.00.0-0.1-0.10.1-0.1-0.10.0-0.1-0.1-0.0-0.1-0.2-0.2-0.20.3
Delay disc. indifference point, 4s delay7.07.49.5-2.42.63.12.7-2.72.62.6-3.03.02.6-2.62.6-2.6-2.62.6-2.6-2.6-2.7-2.6-2.7-2.6-2.6-2.9-2.9-2.92.9
Delay disc. indifference point, 8s delay1.22.02.90.71.41.31.4-1.41.41.4-1.71.71.4-1.41.4-1.4-1.41.4-1.4-1.4-1.3-1.4-1.4-1.3-1.4-1.7-1.6-1.61.6
Indifference point function ln k0.10.33.2-1.80.20.60.5-0.50.40.5-0.50.50.4-0.40.4-0.4-0.50.5-0.5-0.5-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.50.5
Indifference point function log k0.10.33.2-1.80.20.60.5-0.50.40.5-0.50.50.4-0.40.4-0.4-0.50.5-0.5-0.5-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.50.5
Patch foraging total patch changes 0 sec0.10.21.7-1.30.1-0.00.1-0.20.20.4-0.40.40.3-0.30.3-0.3-0.40.4-0.3-0.3-0.4-0.4-0.4-0.4-0.3-0.3-0.2-0.20.2
Patch foraging total patch changes 12 sec0.71.01.3-0.21.20.80.9-0.91.11.1-0.90.91.0-1.01.0-1.0-1.01.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-0.9-0.9-0.90.9
Patch foraging total patch changes 18 sec0.10.20.4-0.20.2-0.00.2-0.20.40.4-0.60.60.4-0.40.4-0.4-0.40.4-0.4-0.4-0.5-0.4-0.4-0.5-0.4-0.4-0.3-0.30.3
Patch foraging total patch changes 24 sec0.51.62.4-1.51.21.21.3-1.31.21.4-1.31.31.2-1.21.2-1.2-1.31.3-1.2-1.2-1.3-1.3-1.3-1.3-1.2-1.2-1.2-1.21.2
Patch foraging total patch changes 6 sec1.72.94.10.81.81.61.6-1.71.82.0-1.71.71.7-1.71.7-1.7-1.71.7-1.7-1.7-1.8-1.7-1.7-1.7-1.7-1.7-1.7-1.71.6
Patch foraging time to switch 0 sec0.20.81.6-1.31.00.80.8-0.80.90.8-1.01.00.9-0.90.9-0.9-0.80.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-1.0-1.0-1.01.0
Patch foraging water rate 0 sec0.62.33.00.7-1.7-1.7-1.71.6-1.5-1.71.5-1.5-1.51.5-1.51.51.5-1.51.51.51.61.51.51.51.51.61.61.6-1.6
Patch foraging water rate 12 sec0.00.11.1-1.00.30.10.2-0.30.30.2-0.40.40.3-0.30.3-0.3-0.40.4-0.3-0.3-0.3-0.3-0.4-0.3-0.3-0.4-0.4-0.40.4
Patch foraging water rate 18 sec0.10.24.4-2.1-0.00.10.2-0.20.00.0-0.00.00.1-0.10.1-0.1-0.10.1-0.1-0.1-0.2-0.1-0.1-0.1-0.1-0.2-0.2-0.20.2
Patch foraging water rate 24 sec0.00.10.50.70.0-0.3-0.10.00.20.1-0.20.20.2-0.20.2-0.2-0.30.3-0.2-0.2-0.1-0.3-0.3-0.3-0.3-0.2-0.1-0.10.1
Patch foraging water rate 6 sec0.20.40.50.6-0.6-0.6-0.50.6-0.6-0.60.7-0.7-0.60.6-0.60.60.6-0.60.60.60.60.60.60.60.60.60.60.6-0.6
Seeking ratio, delayed vs. immediate footshock0.20.32.4-1.60.40.50.9-0.80.40.20.0-0.00.4-0.40.4-0.4-0.40.4-0.4-0.4-0.3-0.4-0.4-0.5-0.4-0.3-0.4-0.40.4
Distance traveled before self-admin0.40.819.14.40.4-0.4-0.20.10.40.1-0.20.20.4-0.30.3-0.4-0.30.3-0.3-0.3-0.2-0.3-0.3-0.2-0.3-0.00.0-0.1-0.0
Distance traveled after self-admin3.45.98.40.82.42.92.4-2.42.52.6-2.52.52.5-2.52.5-2.5-2.52.5-2.5-2.5-2.7-2.5-2.5-2.4-2.5-2.3-2.2-2.22.2
Extensor digitorum longus weight0.41.42.20.71.10.91.1-1.11.21.5-1.21.21.2-1.21.2-1.2-1.21.2-1.2-1.2-1.3-1.2-1.2-1.2-1.2-1.3-1.3-1.31.3
Bone: elastic displacement0.50.60.80.00.90.90.9-0.90.80.8-0.70.70.8-0.80.8-0.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.7-0.8-0.80.8
Bone: elastic work0.10.11.81.3-0.1-0.2-0.20.2-0.1-0.00.1-0.1-0.10.1-0.10.10.1-0.10.10.10.10.10.10.10.1-0.0-0.0-0.00.1
Bone: endosteal estimation0.41.11.40.4-1.2-0.9-0.91.0-1.1-0.91.1-1.1-1.01.1-1.11.01.1-1.11.01.01.01.01.01.01.01.11.11.1-1.1
Bone: endosteal perimeter1.12.73.6-1.2-1.9-1.4-1.51.5-1.7-1.61.6-1.6-1.71.7-1.71.71.7-1.71.71.71.61.71.71.61.71.71.71.8-1.8
Epididymis fat weight0.10.43.3-1.8-0.5-0.4-0.30.4-0.6-0.50.5-0.5-0.60.6-0.60.60.6-0.60.60.60.50.60.60.60.60.60.60.7-0.6
Delta time in closed arm before/after self-admin0.10.11.9-1.40.1-0.30.1-0.10.1-0.1-0.10.10.1-0.10.1-0.1-0.10.1-0.1-0.10.1-0.0-0.0-0.0-0.00.10.10.1-0.1
Delta time in open arm before/after self-admin0.40.50.70.3-0.7-0.4-0.80.8-0.8-0.70.6-0.6-0.80.8-0.80.80.8-0.80.80.80.60.70.70.70.70.60.70.7-0.7
Diff in mean of infusions in LGA sessions0.10.11.51.20.20.10.1-0.10.30.3-0.30.30.3-0.30.3-0.3-0.30.3-0.3-0.3-0.1-0.3-0.3-0.3-0.3-0.2-0.2-0.20.2
Delay discount exponential model param2.73.64.80.2-1.8-2.0-1.81.8-1.9-1.82.2-2.2-1.91.9-1.91.91.9-1.91.91.91.91.91.91.91.92.12.12.1-2.1
Extinction: sum of active levers before priming0.60.94.00.3-1.5-2.0-1.71.5-1.0-1.00.6-0.6-0.90.9-0.80.90.8-0.80.80.81.00.80.70.80.70.60.70.6-0.5
Active lever presses in extinction session 60.30.33.21.80.20.10.0-0.10.30.4-0.60.60.4-0.40.4-0.4-0.50.5-0.4-0.4-0.4-0.5-0.5-0.5-0.5-0.5-0.4-0.50.5
Bone: final force0.20.33.31.80.20.10.2-0.20.40.4-0.50.50.4-0.40.4-0.4-0.40.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.6-0.5-0.60.6
Bone: final moment0.20.33.61.90.30.10.2-0.30.40.4-0.50.50.4-0.40.4-0.4-0.50.5-0.5-0.5-0.4-0.4-0.5-0.5-0.5-0.6-0.5-0.60.6
Food consumed during 24 hour testing period0.20.30.5-0.50.40.40.4-0.40.50.5-0.60.60.5-0.50.5-0.5-0.50.6-0.5-0.5-0.6-0.6-0.6-0.6-0.5-0.7-0.7-0.70.7
Glucose0.00.11.0-1.0-0.1-0.00.2-0.1-0.1-0.10.1-0.1-0.10.1-0.10.10.1-0.10.10.10.10.10.10.10.10.20.20.2-0.3
Heart weight2.94.614.5-3.81.82.52.3-2.31.92.2-2.12.12.0-2.02.0-2.0-2.02.0-2.0-2.0-2.2-2.0-2.0-2.1-2.0-2.1-2.1-2.02.0
Delay discount hyperbolic model param3.13.95.10.4-1.9-2.2-1.91.9-1.9-1.92.3-2.3-2.02.0-2.02.02.0-2.02.02.02.02.02.01.92.02.22.22.2-2.2
Intermittent access intake day 1-15 change0.10.61.31.0-1.1-1.1-1.11.0-0.9-0.80.8-0.8-0.80.8-0.80.80.8-0.80.80.70.60.70.70.70.70.60.60.6-0.5
Intermittent access intake escalation0.10.61.40.7-1.2-1.1-1.11.0-0.9-0.80.7-0.7-0.70.7-0.70.70.7-0.70.70.70.50.70.70.70.70.50.50.5-0.4
Intermittent access intake escalation 20.10.20.5-0.20.20.30.2-0.30.30.5-0.40.40.3-0.30.4-0.4-0.40.4-0.4-0.4-0.7-0.4-0.4-0.4-0.4-0.5-0.5-0.50.6
Intermitt. access day 1 inactive lever presses0.22.13.7-1.90.71.11.0-1.11.21.3-1.81.81.3-1.41.4-1.3-1.41.4-1.4-1.4-1.6-1.4-1.5-1.5-1.5-1.7-1.6-1.61.6
Intermitt. access day 15 inactive lever presses0.00.10.60.2-0.8-0.8-0.60.5-0.3-0.30.0-0.0-0.20.2-0.20.20.2-0.20.20.1-0.00.10.10.10.1-0.00.00.00.0
Intermitt. access escalation Index0.31.13.00.91.61.71.3-1.21.21.1-0.80.81.0-1.01.0-1.0-1.01.0-1.0-1.0-1.0-1.0-0.9-1.0-1.0-0.6-0.7-0.70.6
Intermittent access day 1 total infusions1.03.03.8-0.7-2.0-1.4-1.71.7-1.8-1.61.5-1.5-1.81.8-1.81.81.8-1.81.81.81.71.81.81.81.81.81.81.8-1.8
Intermittent access day 15 total infusions1.02.44.00.0-2.0-1.6-1.91.8-1.7-1.61.4-1.4-1.61.6-1.61.61.6-1.61.61.61.41.51.51.61.51.31.41.4-1.3
Intermittent access terminal intake (last 3 days)1.42.54.2-0.4-2.0-1.7-1.81.8-1.8-1.61.4-1.4-1.71.6-1.61.61.6-1.61.61.61.41.61.61.61.61.41.41.4-1.4
Intermittent access total infusions1.72.03.3-0.2-1.8-1.3-1.61.6-1.6-1.31.3-1.3-1.51.5-1.51.51.5-1.51.51.41.31.41.41.41.41.31.31.3-1.3
Intermittent access day 1 locomotion0.20.30.8-0.9-0.9-0.5-0.50.5-0.6-0.60.1-0.1-0.60.6-0.60.60.5-0.50.60.50.40.50.50.50.50.40.50.5-0.5
Intermittent access day 15 total locomotion0.72.64.4-0.2-2.1-1.5-1.61.6-1.7-1.81.4-1.4-1.71.7-1.71.71.7-1.71.71.71.51.71.71.71.71.41.51.5-1.5
Intermittent access total locomotion2.32.75.2-0.7-2.3-1.7-1.91.8-1.9-1.81.3-1.3-1.71.7-1.71.71.7-1.71.71.71.51.71.71.71.71.41.51.5-1.4
Intermittent access standard deviation0.31.73.10.7-1.8-1.6-1.51.5-1.4-1.41.3-1.3-1.31.3-1.31.31.3-1.31.31.31.21.31.31.31.31.11.11.1-1.1
Left kidney weight0.11.12.8-1.70.70.80.9-0.90.91.1-1.21.21.0-1.01.0-1.0-1.01.0-1.0-1.0-1.1-1.0-1.0-1.1-1.0-1.2-1.1-1.11.2
Right kidney weight0.00.11.3-1.1-0.1-0.00.1-0.1-0.10.2-0.10.1-0.00.0-0.00.00.0-0.00.00.0-0.10.00.00.00.0-0.1-0.0-0.00.1
Cocaine induced anxiety0.00.00.1-0.20.2-0.30.1-0.10.0-0.20.0-0.0-0.00.0-0.00.00.0-0.00.00.0-0.00.00.00.00.00.10.10.1-0.1
Post-drug Anxiety0.10.11.4-1.2-0.1-0.3-0.00.1-0.2-0.40.1-0.1-0.20.2-0.20.20.3-0.30.20.20.20.30.30.30.30.10.10.1-0.1
Baseline Anxiety0.10.21.9-1.4-0.40.1-0.20.2-0.4-0.40.2-0.2-0.40.4-0.40.40.4-0.40.40.40.40.40.40.40.40.20.10.1-0.1
Tail length0.21.37.52.70.80.30.6-0.71.01.1-1.01.01.1-1.11.1-1.1-1.11.1-1.1-1.1-0.9-1.1-1.1-1.1-1.1-1.2-1.1-1.21.2
Length with tail0.10.35.32.3-0.4-0.9-0.60.5-0.2-0.20.0-0.0-0.20.2-0.20.20.1-0.10.10.10.30.10.10.10.10.10.20.1-0.1
Length without tail0.63.03.6-1.6-1.7-1.7-1.71.7-1.8-1.81.5-1.5-1.81.7-1.71.81.7-1.71.71.71.71.71.71.71.71.81.91.9-1.9
Times rat made contact with spout1.21.31.60.4-1.2-1.2-1.21.2-1.2-1.31.2-1.2-1.21.2-1.21.21.2-1.21.21.21.21.21.21.21.21.11.11.1-1.1
Lifetime Intake0.60.71.7-0.5-1.3-0.8-1.01.0-1.0-0.80.8-0.8-0.90.9-0.90.90.9-0.90.90.90.70.90.80.90.80.70.80.8-0.7
Liver weight, left0.00.00.1-0.0-0.00.00.2-0.20.10.2-0.20.20.2-0.20.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.3-0.2-0.20.3
Liver weight, right1.32.23.2-0.8-1.8-1.6-1.61.6-1.6-1.51.4-1.4-1.51.5-1.51.51.5-1.51.51.51.51.51.51.41.51.51.51.5-1.5
Locomotor activity0.40.63.81.9-0.8-0.7-0.80.8-0.7-0.70.8-0.8-0.70.7-0.70.70.7-0.70.70.70.80.70.70.80.70.60.60.6-0.6
Locomotor testing distance0.20.65.12.3-0.9-0.8-0.80.8-0.6-0.70.5-0.5-0.60.6-0.60.60.6-0.60.60.60.60.60.60.60.60.30.30.3-0.3
Locomotor testing rearing0.10.21.51.2-0.5-0.7-0.60.6-0.4-0.70.4-0.4-0.40.4-0.40.40.4-0.40.40.40.50.40.40.40.40.20.20.2-0.1
Locomotion in novel chamber0.91.31.6-0.21.21.01.3-1.31.21.2-1.11.11.2-1.21.2-1.2-1.21.2-1.2-1.2-1.2-1.1-1.1-1.2-1.1-1.1-1.1-1.11.0
Locomotion in novel chamber post-restriction0.61.75.4-2.31.52.11.6-1.51.21.6-1.21.21.1-1.21.1-1.1-1.11.1-1.1-1.1-1.4-1.1-1.1-1.1-1.1-1.1-1.1-1.11.0
Fecal boli incidents, locomotor time 10.82.12.91.31.70.81.6-1.61.61.4-1.31.31.6-1.51.5-1.6-1.51.5-1.5-1.5-1.4-1.5-1.5-1.4-1.5-1.3-1.4-1.41.4
Change in fecal boli incidents, locomotor task0.10.21.81.4-0.1-0.1-0.30.20.20.4-0.10.10.3-0.20.3-0.3-0.30.3-0.3-0.3-0.2-0.3-0.3-0.3-0.3-0.4-0.5-0.50.5
Time >=10cm from walls, locomotor time 10.70.87.62.80.90.60.3-0.40.81.1-0.50.50.8-0.80.8-0.8-0.80.8-0.8-0.8-0.9-0.8-0.8-0.7-0.8-0.7-0.7-0.70.7
Bouts of movement, locomotor time 10.10.20.9-0.90.40.70.5-0.50.30.4-0.40.40.3-0.30.3-0.3-0.30.3-0.3-0.3-0.4-0.3-0.4-0.3-0.3-0.4-0.3-0.40.4
Total resting periods, locomotor time 10.10.12.2-1.50.10.30.2-0.2-0.1-0.1-0.10.1-0.00.0-0.00.00.0-0.00.00.0-0.00.0-0.00.10.0-0.1-0.1-0.10.1
Rest time, locomotor task time 12.23.614.9-3.9-2.1-1.9-1.91.8-2.0-2.11.5-1.5-1.91.8-1.81.81.8-1.81.81.81.71.81.71.81.81.51.51.5-1.5
Distance moved, locomotor task time 10.41.230.25.50.40.0-0.10.10.30.30.0-0.00.1-0.10.1-0.1-0.10.1-0.1-0.10.0-0.0-0.0-0.0-0.10.10.10.0-0.1
Vertical activity count, locomotor time 10.21.229.25.4-0.0-0.3-0.40.4-0.10.20.4-0.4-0.10.2-0.20.10.2-0.20.20.20.30.20.20.20.20.20.20.2-0.2
Time >=10cm from walls, locomotor time 20.20.612.93.6-0.1-0.3-0.60.50.10.1-0.40.40.2-0.10.1-0.2-0.20.2-0.1-0.2-0.2-0.2-0.2-0.1-0.2-0.4-0.2-0.30.4
Bouts of movement, locomotor time 20.20.512.4-3.5-0.6-0.1-0.0-0.0-0.3-0.00.0-0.0-0.20.1-0.10.20.1-0.10.10.1-0.10.10.00.00.0-0.2-0.1-0.10.2
Total resting periods, locomotor time 20.20.613.0-3.6-0.9-0.4-0.30.3-0.6-0.30.4-0.4-0.50.4-0.40.50.4-0.40.40.40.20.40.30.30.30.10.10.2-0.1
Rest time, locomotor task time 21.42.33.70.8-1.8-1.9-1.91.9-1.6-1.71.6-1.6-1.51.5-1.51.51.5-1.51.51.51.61.51.51.51.51.31.21.2-1.1
Distance moved, locomotor task time 20.81.16.72.60.91.00.6-0.60.91.0-1.31.30.9-0.90.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.7-0.80.7
Vertical activity count, locomotor time 20.30.612.63.60.40.0-0.0-0.10.40.5-0.50.50.4-0.40.4-0.4-0.40.4-0.4-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.3-0.30.3
Light reinforcement 10.94.08.83.0-2.1-2.1-2.32.2-1.9-2.01.8-1.8-1.91.9-1.91.91.9-1.91.91.91.91.91.91.91.91.81.91.8-1.8
Light reinforcement 21.12.54.42.1-1.5-1.1-1.51.5-1.5-1.51.7-1.7-1.51.6-1.61.51.6-1.61.61.61.51.61.61.61.61.61.61.5-1.6
Bone: marrow area0.30.81.10.2-1.1-0.8-0.80.8-0.9-0.81.0-1.0-0.90.9-0.90.90.9-0.90.90.90.90.90.90.90.91.01.01.0-1.0
Bone: maximum diameter0.81.52.00.6-1.4-1.2-1.21.2-1.3-1.11.3-1.3-1.31.3-1.31.31.3-1.31.31.31.31.31.31.31.21.21.21.2-1.2
Bone: maximum force0.00.11.31.1-0.3-0.4-0.40.3-0.2-0.1-0.00.0-0.10.1-0.10.10.1-0.10.10.10.10.10.10.10.1-0.00.0-0.00.1
Bone: maximum moment0.00.11.41.2-0.3-0.4-0.30.3-0.1-0.1-0.00.0-0.10.1-0.10.10.1-0.10.10.10.10.10.10.10.1-0.00.0-0.00.0
Mean time between licks in bursts0.10.30.70.4-0.5-0.4-0.40.5-0.5-0.30.6-0.6-0.60.6-0.60.60.6-0.60.60.60.50.60.60.60.60.80.80.8-0.8
Mean num. licks in bursts0.20.49.2-3.00.30.50.6-0.60.20.1-0.20.20.2-0.30.3-0.2-0.30.3-0.3-0.2-0.3-0.3-0.3-0.3-0.2-0.3-0.3-0.20.2
Cd content in liver2.52.83.3-1.71.41.51.6-1.61.51.6-1.71.71.6-1.61.6-1.6-1.71.7-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.8-1.7-1.81.8
Co content in liver4.75.66.60.52.62.12.2-2.22.52.2-2.42.42.5-2.52.5-2.5-2.52.5-2.5-2.5-2.4-2.4-2.5-2.4-2.4-2.4-2.4-2.42.4
Cu content in liver0.10.10.50.70.40.20.3-0.30.40.2-0.30.30.4-0.30.3-0.4-0.30.3-0.3-0.3-0.2-0.3-0.3-0.3-0.3-0.3-0.3-0.30.3
Fe content in liver0.50.61.01.0-0.7-1.0-1.00.9-0.7-0.90.8-0.8-0.70.8-0.80.70.8-0.80.80.80.80.70.70.80.70.60.60.6-0.6
K content in liver0.30.31.21.10.50.50.3-0.30.50.4-0.50.50.5-0.50.5-0.5-0.50.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.50.5
Mg content in liver1.41.51.8-0.61.31.41.2-1.21.31.2-1.21.21.2-1.21.2-1.2-1.21.2-1.2-1.2-1.3-1.2-1.2-1.2-1.2-1.2-1.2-1.21.2
Mn content in liver0.10.10.4-0.60.40.50.4-0.40.40.4-0.30.30.3-0.30.3-0.3-0.30.3-0.3-0.3-0.4-0.3-0.3-0.3-0.3-0.3-0.4-0.40.4
Na content in liver1.01.21.8-0.4-1.3-1.1-1.21.2-1.2-1.11.0-1.0-1.11.1-1.11.11.1-1.11.11.11.01.11.11.11.11.01.11.0-1.0
Rb content in liver4.14.75.30.72.31.82.0-2.02.32.2-2.22.22.3-2.32.3-2.3-2.32.3-2.3-2.3-2.2-2.3-2.3-2.2-2.3-2.2-2.2-2.32.2
Se content in liver1.11.31.91.1-1.1-1.3-1.41.4-1.1-1.41.1-1.1-1.11.1-1.11.11.1-1.11.11.11.21.11.11.11.11.01.01.0-0.9
Sr content in liver0.60.60.7-0.5-0.7-0.6-0.60.6-0.8-0.80.8-0.8-0.80.8-0.80.80.8-0.80.80.80.80.80.80.80.80.80.80.8-0.8
Zn content in liver1.41.73.1-1.81.21.51.3-1.31.21.2-1.41.31.2-1.21.2-1.2-1.31.3-1.2-1.3-1.3-1.3-1.3-1.3-1.2-1.2-1.2-1.21.2
Bone: minimum diameter0.00.00.1-0.3-0.20.10.1-0.1-0.10.10.0-0.0-0.10.1-0.10.10.1-0.10.10.00.00.10.10.00.00.00.00.00.0
Time in familiar zone, hab. session 10.00.00.1-0.3-0.2-0.3-0.30.2-0.1-0.10.1-0.1-0.10.1-0.10.10.1-0.10.10.10.10.10.10.10.10.20.20.2-0.2
Time in novel zone, hab. session 10.20.30.50.7-0.5-0.4-0.40.4-0.5-0.50.5-0.5-0.50.5-0.50.50.5-0.50.50.50.50.50.50.50.50.50.50.5-0.5
Total zone transitions, hab. session 11.21.72.0-1.21.31.31.3-1.31.31.2-1.41.41.3-1.31.3-1.3-1.31.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.4-1.4-1.31.3
Total locomotion distance, hab. session 11.01.41.6-1.11.01.31.1-1.11.11.2-1.31.31.1-1.21.2-1.1-1.21.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.21.2
Locomotion velocity, hab. session 11.31.92.3-1.11.31.51.3-1.41.31.4-1.41.41.4-1.41.4-1.4-1.41.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.41.4
Time in familiar zone, hab. session 21.21.41.90.01.41.21.1-1.11.21.1-1.21.21.2-1.21.2-1.2-1.21.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.21.2
Time in novel zone, hab. session 20.40.40.60.2-0.8-0.7-0.60.6-0.7-0.60.7-0.7-0.70.7-0.70.70.7-0.70.70.70.70.70.70.70.70.70.80.7-0.8
Total zone transitions, hab. session 21.31.72.2-0.31.51.51.4-1.41.41.3-1.31.31.3-1.31.3-1.3-1.31.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.31.3
Total locomotion distance, hab. session 20.50.61.10.30.81.00.8-0.80.80.9-0.80.80.8-0.80.8-0.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.7-0.7-0.70.7
Locomotion velocity, hab. session 20.40.51.00.00.71.00.8-0.70.70.8-0.70.70.7-0.70.7-0.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.70.6
Novel to familiar place preference ratio0.10.10.2-0.3-0.4-0.2-0.20.2-0.4-0.30.4-0.4-0.40.4-0.40.40.4-0.40.40.40.40.40.40.40.40.50.40.4-0.4
Novelty place preference0.10.10.2-0.2-0.4-0.2-0.20.2-0.4-0.30.4-0.4-0.40.4-0.40.40.4-0.40.40.40.40.40.40.40.40.50.40.4-0.5
Time in novel zone, NPP test0.00.00.2-0.5-0.00.20.2-0.2-0.00.10.1-0.1-0.00.0-0.00.00.0-0.00.00.0-0.00.00.00.00.00.10.10.1-0.1
Total zone transitions, NPP test1.52.22.5-0.81.51.31.4-1.41.51.3-1.61.61.5-1.51.5-1.5-1.51.5-1.5-1.5-1.4-1.5-1.5-1.5-1.5-1.5-1.5-1.51.5
Total locomotion distance, NPP test0.00.00.10.30.20.30.1-0.20.20.2-0.20.20.2-0.20.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.2
Locomotion velocity, NPP test0.00.00.30.6-0.1-0.1-0.20.2-0.1-0.20.2-0.2-0.10.1-0.10.10.2-0.20.20.20.20.20.20.20.10.20.20.2-0.2
Intraocular pressure0.00.00.60.70.2-0.30.1-0.10.10.1-0.10.10.1-0.10.1-0.1-0.10.1-0.1-0.00.0-0.1-0.0-0.0-0.1-0.0-0.0-0.00.0
Delta distance traveled before/after self-admin5.66.114.9-3.92.23.22.7-2.72.22.6-2.52.52.3-2.32.3-2.3-2.32.3-2.3-2.3-2.5-2.3-2.3-2.3-2.3-2.4-2.3-2.32.3
Delta ambulatory time before/after self-admin3.86.533.9-5.82.13.32.8-2.72.12.5-2.42.42.2-2.22.2-2.2-2.22.2-2.2-2.2-2.4-2.2-2.2-2.2-2.2-2.2-2.2-2.22.2
Parametrial fat weight0.20.51.10.5-1.0-0.7-0.90.9-0.8-0.70.6-0.6-0.70.7-0.70.70.7-0.70.70.70.70.70.70.70.70.60.60.6-0.5
Pavlov. Cond. lever latency0.00.10.8-0.9-0.1-0.1-0.00.0-0.2-0.10.1-0.1-0.10.1-0.10.10.1-0.10.10.10.10.10.10.10.10.20.20.3-0.3
Pavlov. Cond. magazine entry latency0.10.10.30.30.30.50.4-0.40.40.4-0.30.30.4-0.40.4-0.4-0.40.4-0.4-0.4-0.4-0.4-0.3-0.3-0.3-0.4-0.4-0.40.4
Pavlov. Cond. change in total contacts0.00.00.90.90.10.1-0.10.10.0-0.10.1-0.1-0.00.0-0.00.00.0-0.00.00.00.10.00.00.00.0-0.0-0.1-0.10.1
Pavlov. Cond. index score0.00.00.80.90.10.10.0-0.00.10.1-0.10.10.1-0.10.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.2-0.20.2
Pavlov. Cond. latency score0.10.11.01.00.10.20.0-0.10.20.2-0.10.10.2-0.20.2-0.2-0.10.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.2-0.2-0.20.2
Pavlov. Cond. lever contacts0.00.00.60.8-0.0-0.0-0.10.10.0-0.00.0-0.0-0.00.0-0.00.00.0-0.00.00.00.00.00.00.00.0-0.0-0.1-0.10.1
Pavlov. Cond. magazine entry number0.00.10.7-0.80.10.00.2-0.20.10.2-0.30.30.2-0.20.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.2
Pavlov. Cond. intertrial magazine entries0.30.30.40.60.50.40.4-0.40.60.4-0.60.60.6-0.60.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.60.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.70.80.30.30.2-0.20.30.3-0.30.30.3-0.30.3-0.3-0.30.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.4-0.40.4
Pavlov. Cond. response bias0.00.00.30.50.00.10.00.00.0-0.00.1-0.1-0.00.0-0.00.00.0-0.00.00.00.10.00.00.00.0-0.0-0.1-0.00.0
Pavlov. Cond. lever latency0.60.91.81.30.90.70.7-0.80.91.0-0.90.91.0-0.90.9-1.0-0.90.9-0.9-0.9-0.9-0.9-0.9-0.9-1.0-0.9-0.8-0.90.9
Pavlov. Cond. magazine entry latency3.55.05.5-0.6-2.2-2.0-2.12.1-2.3-2.22.3-2.3-2.32.3-2.32.32.3-2.32.32.32.32.32.32.32.32.32.32.3-2.3
Pavlov. Cond. change in total contacts0.40.91.4-1.2-0.9-0.8-0.80.8-1.0-1.00.9-0.9-1.01.0-1.01.01.0-1.01.01.01.01.01.00.91.00.80.80.8-0.8
Pavlov. Cond. index score1.82.83.0-1.1-1.6-1.4-1.51.5-1.7-1.71.7-1.7-1.71.7-1.71.71.7-1.71.71.71.71.71.71.71.71.71.61.7-1.7
Pavlov. Cond. latency score1.62.62.8-0.8-1.6-1.4-1.41.5-1.7-1.71.7-1.7-1.71.7-1.71.71.7-1.71.71.71.61.71.71.61.71.61.61.6-1.6
Pavlov. Cond. lever contacts1.01.52.3-1.5-1.2-1.0-1.01.0-1.3-1.31.2-1.2-1.31.3-1.31.31.3-1.31.31.31.31.31.31.31.31.21.11.2-1.2
Pavlov. Cond. magazine entry number2.83.64.10.51.81.61.7-1.81.91.9-2.02.02.0-2.02.0-2.0-2.02.0-2.0-2.0-2.0-2.0-2.0-2.0-2.0-2.0-2.0-2.02.0
Pavlov. Cond. intertrial magazine entries0.20.41.21.10.50.40.4-0.40.60.6-0.70.70.6-0.60.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.60.6
Pavlov. Cond. lever-magazine prob. diff.1.72.62.9-1.0-1.6-1.4-1.41.5-1.7-1.71.7-1.7-1.71.7-1.71.71.7-1.71.71.71.71.71.71.71.71.71.61.7-1.7
Pavlov. Cond. response bias2.02.73.0-1.4-1.6-1.4-1.41.5-1.7-1.71.7-1.7-1.71.7-1.71.71.7-1.71.71.71.71.71.71.71.71.71.61.7-1.7
Time in closed arm before self-admin0.40.715.03.90.30.5-0.10.1-0.1-0.00.4-0.4-0.20.2-0.20.20.3-0.30.30.30.30.30.30.30.30.30.20.2-0.2
Time in closed arm after self-admin1.11.32.30.61.51.21.3-1.21.21.1-1.11.11.2-1.11.1-1.2-1.11.1-1.1-1.1-1.0-1.1-1.1-1.1-1.1-1.1-1.1-1.11.1
Time in open arm before self-admin1.01.217.2-4.10.5-0.21.0-1.00.80.5-0.80.80.8-0.80.8-0.8-0.80.8-0.8-0.8-0.6-0.8-0.8-0.8-0.8-0.7-0.7-0.60.6
Time in open arm after self-admin0.70.86.5-2.5-1.1-0.6-0.70.7-0.8-0.90.8-0.8-0.80.8-0.80.80.8-0.80.80.70.40.70.70.70.80.70.80.8-0.8
Bone: periosteal estimation0.30.71.10.4-1.0-0.8-0.80.8-0.9-0.70.9-0.9-0.90.9-0.90.90.9-0.90.90.90.90.90.90.90.90.80.80.8-0.8
Bone: periosteal perimeter0.61.11.50.3-1.2-1.0-1.01.0-1.1-1.01.1-1.1-1.11.1-1.11.11.1-1.11.11.11.11.11.11.11.11.11.11.0-1.0
Bone: post-yield work0.10.20.3-0.5-0.4-0.5-0.50.5-0.4-0.50.3-0.3-0.40.4-0.40.40.4-0.40.40.40.50.40.40.40.40.40.40.4-0.4
Progressive ratio test 1 active lever presses1.22.12.60.6-1.4-0.9-1.21.3-1.4-1.31.6-1.6-1.51.5-1.51.51.5-1.51.51.51.41.51.51.51.51.61.51.5-1.6
Progressive ratio test 1 breakpoint1.11.92.50.7-1.3-0.9-1.21.2-1.4-1.31.6-1.6-1.41.4-1.41.41.5-1.51.41.51.41.41.51.41.41.61.51.5-1.5
Progressive ratio test 1 inactive lever presses0.82.03.30.1-1.8-0.9-1.51.5-1.5-1.51.3-1.3-1.51.5-1.51.51.5-1.51.51.41.41.41.41.41.41.41.41.4-1.4
Progressive ratio test 2 active lever presses1.92.73.31.2-1.8-1.8-1.81.7-1.7-1.51.7-1.7-1.71.7-1.71.71.7-1.71.71.61.51.61.61.61.61.61.51.5-1.5
Progressive ratio test 2 breakpoint2.02.63.41.0-1.8-1.8-1.71.7-1.7-1.51.7-1.7-1.61.6-1.61.61.6-1.61.61.61.41.61.61.61.61.51.51.5-1.4
Progressive ratio test 2 inactive lever presses0.10.30.80.1-0.9-0.5-0.70.6-0.6-0.40.5-0.5-0.50.6-0.60.50.5-0.50.50.50.30.50.50.50.50.40.40.4-0.3
Incentive Sensitization - Responses1.33.65.81.2-2.1-2.4-2.32.2-2.0-1.81.8-1.8-1.91.9-1.91.91.9-1.91.91.91.71.91.81.91.91.71.81.7-1.7
Incentive Sensitization - Breakpoint1.73.96.11.0-2.2-2.5-2.32.3-2.1-1.91.8-1.8-2.02.0-2.02.02.0-2.02.02.01.81.91.92.02.01.81.81.8-1.7
Sum of active levers in priming session hrs 5-60.50.57.3-2.7-1.2-0.9-0.90.8-0.7-0.4-0.00.0-0.40.4-0.40.40.3-0.30.40.30.30.30.20.20.2-0.00.10.10.0
Progressive ratio0.20.611.13.30.2-0.3-0.0-0.10.40.2-0.40.40.5-0.50.5-0.5-0.50.5-0.5-0.5-0.4-0.5-0.5-0.4-0.5-0.5-0.5-0.50.5
Food seeking constrained by brief footshock0.20.31.5-0.30.41.20.5-0.50.41.0-0.70.70.4-0.40.4-0.4-0.40.4-0.4-0.4-0.7-0.4-0.4-0.5-0.5-0.4-0.3-0.30.3
Seeking ratio, punishment vs. effort0.10.21.6-1.3-0.10.3-0.10.1-0.4-0.20.4-0.4-0.40.4-0.40.40.4-0.40.40.40.40.40.50.40.40.50.50.6-0.6
Retroperitoneal fat weight1.46.37.40.5-2.7-2.5-2.72.6-2.6-2.52.4-2.4-2.62.6-2.62.62.6-2.62.62.52.52.62.52.52.62.52.52.5-2.5
Reaction time number correct0.10.51.6-1.30.90.70.8-0.80.60.4-0.70.70.6-0.60.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.7-0.7-0.70.7
Reaction time mean minus median0.10.40.90.9-0.5-0.6-0.60.6-0.6-0.40.8-0.8-0.60.6-0.60.60.6-0.60.60.60.60.60.60.60.60.80.80.8-0.8
Reaction time mean minus median AUC0.00.36.12.50.1-0.1-0.00.1-0.00.00.3-0.3-0.10.1-0.10.10.1-0.10.10.20.20.20.20.20.10.30.30.2-0.3
Reaction time num false alarms0.10.11.8-1.40.00.30.2-0.20.10.1-0.30.30.1-0.10.1-0.1-0.10.1-0.1-0.2-0.3-0.2-0.2-0.2-0.1-0.2-0.1-0.10.1
Reaction time num false alarms AUC0.00.10.2-0.20.20.30.2-0.20.20.3-0.40.40.2-0.20.2-0.2-0.20.2-0.2-0.3-0.4-0.3-0.3-0.3-0.3-0.2-0.2-0.20.2
Reaction time trials correct on left0.10.51.6-1.30.90.70.8-0.80.60.4-0.70.70.6-0.60.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.7-0.7-0.70.7
Reaction time trials on left0.10.41.3-1.20.80.70.8-0.70.60.4-0.60.60.6-0.60.6-0.6-0.60.6-0.5-0.5-0.6-0.5-0.5-0.5-0.5-0.6-0.6-0.60.6
Reaction time mean2.75.97.11.2-2.3-2.2-2.32.3-2.4-2.32.7-2.7-2.52.5-2.52.52.5-2.52.52.52.52.52.52.52.52.62.52.6-2.6
Reaction time mean AUC2.35.56.71.6-2.0-2.0-2.12.2-2.2-2.22.6-2.6-2.32.3-2.32.32.4-2.42.42.42.42.42.42.42.42.62.52.5-2.6
Median of all reaction times5.07.89.31.5-2.6-2.6-2.62.7-2.7-2.73.0-3.0-2.82.8-2.82.82.9-2.92.82.92.92.92.92.92.92.92.92.9-2.9
Reaction time omissions1.42.32.81.3-1.3-1.7-1.51.5-1.5-1.51.6-1.6-1.51.5-1.51.51.5-1.51.51.51.61.51.51.61.51.51.51.5-1.5
Reaction time false alarm rate0.10.20.40.5-0.7-0.4-0.60.5-0.5-0.30.3-0.3-0.40.4-0.40.40.4-0.40.40.40.30.40.40.40.40.50.50.5-0.5
Reaction time premature initiation rate0.10.20.40.30.1-0.10.0-0.10.30.1-0.40.40.4-0.40.4-0.4-0.50.5-0.4-0.5-0.4-0.5-0.5-0.5-0.5-0.6-0.6-0.60.7
Reaction time premature initiations0.10.40.7-0.20.50.20.4-0.40.60.2-0.60.60.6-0.60.6-0.6-0.70.7-0.6-0.6-0.6-0.7-0.7-0.7-0.7-0.8-0.8-0.80.9
Std. dev. reaction times0.30.91.20.9-0.8-0.7-0.80.9-0.9-0.81.1-1.1-0.90.9-0.90.90.9-0.90.90.90.90.90.90.90.91.11.11.1-1.1
Reaction time trials completed0.10.41.3-1.20.80.70.8-0.70.60.4-0.60.60.6-0.60.6-0.6-0.60.6-0.5-0.5-0.6-0.5-0.5-0.5-0.5-0.6-0.6-0.60.6
Reaction time trials AUC0.10.52.4-1.50.90.70.8-0.80.60.4-0.70.70.6-0.60.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.7-0.7-0.70.7
Run reversals in cocaine runway, females0.91.011.83.40.80.20.5-0.50.80.7-0.60.60.8-0.80.8-0.8-0.80.8-0.8-0.8-0.6-0.8-0.8-0.8-0.9-0.8-0.8-0.80.8
Run reversals in cocaine runway, males2.12.35.82.4-1.1-1.8-1.41.5-1.4-1.71.2-1.2-1.41.4-1.41.41.5-1.51.51.51.71.51.51.51.51.51.61.6-1.6
Latency to leave start box in cocaine runway2.73.85.22.1-1.8-2.3-2.22.1-1.9-2.21.7-1.7-1.91.9-1.91.91.9-1.91.91.92.11.91.91.91.91.81.91.9-1.9
Latency to leave start box in cocaine runway, F2.22.73.90.2-1.7-2.0-1.81.8-1.7-1.71.5-1.5-1.71.7-1.71.71.7-1.71.71.71.71.71.61.71.71.61.61.6-1.6
Latency to leave start box in cocaine runway, M2.22.111.13.3-1.0-1.2-1.41.4-1.2-1.71.3-1.3-1.21.3-1.31.21.3-1.31.31.31.51.31.31.41.31.41.41.3-1.4
Std. dev. time between licks in bursts1.01.92.8-0.71.41.61.5-1.51.41.7-1.41.41.4-1.41.4-1.4-1.41.4-1.4-1.4-1.5-1.4-1.4-1.4-1.4-1.3-1.3-1.31.3
Total sessions with >9 infusions0.10.10.6-0.0-0.8-0.2-0.40.4-0.4-0.30.2-0.2-0.30.3-0.30.30.2-0.20.30.20.20.20.20.20.20.30.30.3-0.3
Short access day 1 total inactive lever presses0.10.20.9-0.9-0.1-0.40.0-0.10.20.1-0.50.50.3-0.30.3-0.3-0.40.4-0.4-0.4-0.3-0.4-0.4-0.4-0.4-0.5-0.4-0.40.5
Short access day 10 total inactive lever presses0.00.10.20.1-0.10.00.0-0.10.20.2-0.50.50.2-0.20.2-0.2-0.20.2-0.2-0.3-0.2-0.3-0.3-0.3-0.3-0.3-0.3-0.30.3
Short access day 1 total infusions0.00.00.10.0-0.0-0.1-0.1-0.00.20.2-0.30.30.2-0.20.3-0.2-0.30.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.1-0.20.2
Short access day 10 total infusions0.71.21.51.0-1.2-1.1-1.21.2-1.1-0.81.1-1.1-1.11.1-1.11.11.1-1.11.11.11.01.11.11.01.01.21.21.2-1.2
Short access total infusions0.10.10.30.6-0.5-0.3-0.40.4-0.2-0.10.2-0.2-0.20.2-0.20.20.2-0.20.20.20.10.20.20.20.20.30.40.3-0.3
Short access day 1 locomotion0.00.11.1-1.1-0.6-0.2-0.40.3-0.2-0.1-0.30.3-0.10.1-0.10.10.0-0.00.10.0-0.10.00.0-0.00.0-0.10.00.00.0
Short access day 10 total locomotion0.31.11.90.8-1.4-1.3-1.31.2-1.1-0.90.7-0.7-1.01.0-1.01.01.0-1.01.01.00.81.01.01.01.00.91.11.0-1.0
Short access total locomotion0.30.41.20.2-1.1-0.7-0.90.9-0.7-0.60.2-0.2-0.70.7-0.70.70.6-0.60.70.60.50.60.60.60.60.50.70.6-0.7
One hour access (0.3 mA shock)0.30.30.4-0.2-0.5-0.0-0.40.5-0.6-0.30.6-0.6-0.60.6-0.60.60.6-0.60.60.60.40.60.60.70.60.60.60.6-0.6
Compulsive drug intake1.01.52.0-0.91.31.11.4-1.41.31.1-1.21.21.2-1.21.2-1.2-1.21.2-1.2-1.2-1.1-1.2-1.2-1.2-1.2-1.2-1.2-1.21.1
One hour access (shock baseline)0.51.41.90.9-1.3-1.0-1.41.4-1.2-0.91.2-1.2-1.21.2-1.21.21.2-1.21.21.21.01.21.21.21.21.11.11.1-1.1
Social response proportion0.30.36.72.60.60.30.1-0.10.40.5-0.10.10.4-0.40.4-0.4-0.30.3-0.3-0.3-0.2-0.3-0.3-0.3-0.3-0.1-0.2-0.20.2
Social responses1.31.716.54.1-0.9-1.0-1.31.2-0.9-0.81.3-1.3-1.01.0-1.01.01.0-1.01.01.01.01.01.01.11.01.11.01.0-1.0
Social time0.40.77.62.8-0.4-0.9-0.90.9-0.5-0.50.7-0.7-0.50.5-0.50.50.6-0.60.60.60.70.60.60.60.60.50.50.5-0.5
Soleus weight1.64.85.41.6-2.3-2.3-2.22.2-2.3-1.92.3-2.3-2.22.2-2.22.22.2-2.22.22.22.12.22.22.22.22.12.12.1-2.1
Bone: stiffness0.10.20.40.5-0.6-0.6-0.60.5-0.5-0.40.3-0.3-0.50.4-0.40.50.4-0.40.40.40.40.40.40.40.40.40.40.4-0.4
Tibialis anterior weight0.51.72.80.81.31.11.3-1.31.31.7-1.31.31.3-1.31.3-1.3-1.31.3-1.3-1.3-1.4-1.3-1.3-1.3-1.3-1.3-1.3-1.41.3
Time to tail flick, vehicle, before self-admin0.40.50.90.10.20.70.5-0.60.50.7-0.90.90.7-0.70.7-0.7-0.80.8-0.7-0.8-0.9-0.8-0.8-0.8-0.8-1.0-0.8-0.90.9
Time to tail flick, vehicle, after self-admin2.65.2130.511.40.1-1.0-1.31.2-0.1-0.50.5-0.5-0.10.1-0.10.10.1-0.10.10.20.40.20.20.30.10.40.40.2-0.3
Time to tail flick, test, before self-admin1.92.24.2-2.1-1.4-1.8-1.21.2-1.5-1.61.5-1.5-1.51.5-1.51.51.4-1.41.51.41.61.41.41.41.51.51.41.5-1.4
Time to tail flick, test, after self-admin0.10.11.51.20.2-0.7-0.20.2-0.0-0.20.3-0.3-0.10.1-0.10.10.1-0.10.10.10.10.10.20.10.10.30.20.2-0.3
Delta time to tail flick, vehicle, before/after SA1.92.041.66.5-0.1-1.2-1.11.0-0.3-0.70.7-0.7-0.40.4-0.40.40.5-0.50.40.50.80.50.50.50.50.70.60.5-0.6
Delta time to tail flick, test, before/after SA1.92.35.22.31.71.81.3-1.31.61.4-1.31.31.5-1.51.5-1.5-1.51.5-1.5-1.5-1.6-1.5-1.4-1.4-1.5-1.4-1.4-1.41.4
Tibia length0.00.00.70.80.10.30.2-0.1-0.00.00.2-0.2-0.10.1-0.10.10.2-0.20.10.20.10.20.20.20.20.10.00.0-0.0
Ambulatory time before self-admin0.72.138.86.21.0-0.40.2-0.21.00.6-0.80.80.9-0.90.9-1.0-0.90.9-0.9-0.9-0.7-0.8-0.9-0.8-0.9-0.6-0.5-0.70.6
Ambulatory time after self-admin3.04.77.3-0.12.22.72.2-2.22.32.2-2.32.32.3-2.22.2-2.3-2.22.2-2.2-2.2-2.3-2.2-2.2-2.2-2.2-2.0-2.0-2.01.9
Bone: tissue strength0.20.20.3-0.0-0.5-0.5-0.50.5-0.4-0.50.3-0.3-0.40.4-0.40.40.4-0.40.40.40.40.40.40.40.40.30.30.3-0.3
Total heroin consumption0.60.71.9-0.5-0.9-1.4-1.00.9-0.8-0.90.7-0.7-0.70.8-0.80.70.7-0.70.70.70.70.70.70.80.80.80.90.8-0.8
Bone: trabecular number0.61.11.9-1.2-1.4-1.2-1.01.0-1.2-1.10.9-0.9-1.11.1-1.11.11.1-1.11.11.11.01.01.01.01.01.01.01.0-1.0
Bone: trabecular spacing0.71.01.30.31.11.10.9-0.91.01.1-0.90.91.0-1.01.0-1.0-1.01.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.01.0
Bone: trabecular thickness0.30.50.8-0.3-0.9-0.7-0.60.6-0.8-0.60.6-0.6-0.70.7-0.70.70.7-0.70.70.70.70.70.70.70.70.70.70.7-0.7
Bone: trabecular tissue density0.30.50.70.1-0.5-0.4-0.50.6-0.7-0.70.8-0.8-0.80.8-0.80.80.8-0.80.80.80.80.80.80.80.80.80.70.8-0.8
Water consumed over 24 hours0.10.20.40.3-0.5-0.7-0.60.5-0.4-0.60.3-0.3-0.40.4-0.40.40.4-0.40.40.40.50.40.40.40.40.20.30.2-0.2
Number of responses in last shaping day0.40.51.51.2-0.6-0.7-0.50.5-0.5-0.91.0-1.0-0.60.6-0.60.60.6-0.60.60.60.80.60.60.60.60.80.70.7-0.7