Hub : Genes

Znf740

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Znf740 0.33 0.14 3.1e-04 0.11 0.05 0.06 0.08 1.1e-03 2.3e-02 1.3e-02 5.6e-03
2 PL gene expression Znf740 0.04 0.03 7.0e-04 0.03 0.02 0.02 0.02 5.8e-04 3.7e-03 6.5e-03 3.8e-03
3 Adipose gene expression Znf740 0.3 0.1 0.0e+00 0.28 0.27 0.28 0.28 6.1e-31 8.0e-30 5.2e-31 5.6e-31
4 Adipose mRNA stability Znf740 0.12 0.06 6.5e-10 0.1 0.09 0.08 0.1 1.4e-11 2.7e-10 5.8e-09 3.9e-11
5 Liver gene expression Znf740 0.04 0.03 2.3e-03 0.03 0.01 0.02 0.02 4.0e-04 7.7e-03 5.5e-03 1.2e-03
6 Brain gene expression Znf740 0.16 0.08 1.8e-09 0.12 0.1 0.11 0.12 3.4e-11 4.9e-10 3.3e-10 7.4e-11
7 NAcc gene expression Znf740 0.21 0.01 1.1e-07 0.05 0.04 0.03 0.04 1.1e-07 1.4e-06 1.1e-05 4.2e-07
8 Liver isoform ratio XM_063264457.1 0.02 0.01 3.3e-03 0 0.02 0.01 0 2.9e-01 5.3e-03 1.4e-02 1.1e-01
9 Adipose isoform ratio XM_063264457.1 0.16 0.07 0.0e+00 0.17 0.19 0.19 0.19 4.8e-19 2.0e-20 1.1e-20 2.4e-20

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.62.84.5-2.1-1.7-1.7-1.9-1.4-1.6-1.60.91.9
Area under the delay curve0.50.51.1-0.6-0.9-0.9-0.6-1.1-0.5-0.70.70.4
BMI with tail2.17.111.5-3.4-2.5-2.7-3.0-2.6-2.5-2.72.71.5
BMI without tail1.13.34.2-1.5-2.1-2.0-1.8-2.0-1.8-1.81.61.8
Body weight0.83.44.1-2.0-1.9-1.9-2.0-1.8-1.9-2.01.41.6
Weight adjusted by age0.71.13.20.81.20.90.90.90.90.9-0.3-1.8
Bone surface3.36.07.7-2.8-2.7-2.6-2.7-2.4-2.4-2.31.62.3
Bone volume2.95.26.3-2.5-2.5-2.4-2.5-2.2-2.3-2.31.72.2
Breakpoint value in progressive ratio session1.61.93.2-1.8-1.5-1.5-1.6-1.4-1.4-1.11.20.9
Number of licking bursts0.10.10.91.0-0.1-0.00.40.1-0.20.1-0.00.2
Context. condit. distance diff. score0.20.20.4-0.6-0.4-0.3-0.6-0.2-0.6-0.40.30.7
Locomotion velocity, session 15.66.010.23.22.42.42.62.52.22.1-2.8-1.7
Locomotion distance, session 13.94.99.93.21.92.12.52.12.02.0-2.0-1.9
Locomotion velocity, session 21.92.25.91.91.11.31.51.61.21.1-2.4-0.7
Locomotion distance, session 23.65.17.22.72.02.02.52.12.32.3-2.1-2.0
Locomotion velocity, session 32.32.76.32.21.51.41.61.61.51.2-2.5-0.4
Locomotion distance, session 31.61.85.21.51.11.21.21.51.10.9-2.3-0.3
Stereotopy head waving bouts, day 31.31.53.0-1.2-1.2-1.4-1.2-1.4-1.2-1.21.70.5
Stereotopy head waving duration, day 30.40.40.6-0.5-0.7-0.8-0.7-0.8-0.7-0.70.60.3
Locomotion velocity, session 70.70.81.21.10.91.01.00.80.91.0-0.6-0.6
Locomotion distance, session 72.22.85.52.31.51.51.91.41.41.7-1.9-1.2
Stereotopy head waving bouts, day 71.31.54.7-1.0-1.0-1.2-1.0-1.3-0.9-1.12.20.6
Stereotopy head waving duration, day 71.62.03.7-1.2-1.3-1.4-1.3-1.6-1.2-1.31.91.1
Locomotion velocity, session 80.00.00.00.20.20.10.10.10.1-0.0-0.2-0.0
Locomotion distance, session 82.13.14.42.11.51.81.81.91.61.7-2.0-1.3
Degree of sensitization distance0.10.10.60.30.10.00.2-0.20.00.40.6-0.8
Degree of sensitization stereotypy1.01.02.9-0.8-0.9-0.9-0.9-1.1-0.8-1.01.70.6
Conditioned locomotion0.91.01.51.01.01.01.01.21.01.0-1.1-1.0
Cocaine response after cond. corrected1.31.63.11.71.11.11.61.11.41.3-0.7-1.0
Cocaine response after cond. not corrected1.41.72.21.31.41.31.51.21.41.4-0.8-1.3
Cocaine response before conditioning0.10.20.4-0.60.60.4-0.10.30.20.3-0.3-0.4
Saline control response0.30.40.7-0.10.70.80.50.80.60.7-0.2-0.8
Bone: connectivity density0.20.31.2-1.1-0.3-0.3-0.7-0.2-0.4-0.4-0.00.3
Bone: cortical apparent density1.52.03.51.91.31.21.70.91.41.60.2-1.8
Bone: cortical area1.31.93.7-1.9-1.5-1.4-1.5-1.3-1.4-1.11.20.9
Bone: cortical porosity0.20.20.9-0.10.40.40.10.50.30.3-0.9-0.1
Bone: cortical porosity0.30.31.1-0.10.50.60.30.80.50.5-1.0-0.2
Bone: cortical thickness0.10.10.2-0.5-0.4-0.4-0.3-0.5-0.4-0.00.50.0
Bone: cortical thickness2.02.33.51.01.51.51.61.51.61.9-1.6-1.4
Bone: cortical tissue density1.62.23.81.91.41.31.81.01.51.60.1-1.8
Condit. Reinf. active minus inactive responses0.80.91.30.71.11.10.91.10.91.0-0.8-1.0
Condit. Reinf. active-inactive response ratio0.50.60.80.40.90.90.60.90.70.8-0.9-0.7
Condit. Reinf. active responses2.02.43.01.21.71.61.51.71.61.7-1.5-1.4
Condit. Reinf. inactive responses2.12.63.31.51.61.61.81.71.71.8-1.5-1.3
Incentive salience index mean0.40.50.70.30.80.80.60.80.70.9-0.5-0.7
Condit. Reinf. lever presses0.00.00.10.0-0.0-0.10.2-0.10.10.20.4-0.1
Condit. Reinf. active minus inactive responses0.30.41.6-0.5-0.5-0.6-0.5-0.7-0.5-0.41.3-0.0
Condit. Reinf. active-inactive response ratio0.20.20.6-0.4-0.4-0.5-0.5-0.6-0.5-0.40.80.4
Condit. Reinf. active responses0.30.42.1-0.4-0.4-0.6-0.4-0.7-0.5-0.41.5-0.4
Condit. Reinf. inactive responses0.20.21.10.40.40.40.40.30.40.40.3-1.0
Condit. Reinf. lever presses0.40.61.40.31.10.80.50.70.70.9-0.3-1.2
Condit. Reinf. lever reinforcers received0.10.20.80.00.1-0.00.0-0.20.00.10.9-0.8
Conditioned reinforcement - actives0.10.20.30.60.20.20.5-0.20.60.40.4-0.6
Conditioned reinforcement - inactives1.42.03.30.81.61.51.41.11.81.8-0.6-1.5
Conditioned locomotion0.10.10.6-0.2-0.4-0.4-0.1-0.80.0-0.00.50.1
Patch foraging indifference point 0 sec1.12.03.71.91.41.51.61.51.11.2-1.1-1.3
Patch foraging indifference point AUC1.21.74.82.21.41.21.41.11.21.0-0.1-1.4
Delay disc. indifference point, 0s delay0.00.00.00.1-0.0-0.10.1-0.2-0.0-0.10.0-0.1
Delay disc. indifference point, 16s delay0.10.10.4-0.6-0.2-0.3-0.5-0.3-0.1-0.40.5-0.2
Delay disc. indifference point, 2s delay2.83.16.9-1.1-1.7-1.9-1.3-2.2-1.5-1.52.61.5
Delay disc. indifference point, 24s delay0.20.20.4-0.6-0.4-0.5-0.5-0.6-0.2-0.40.50.1
Delay disc. indifference point, 4s delay0.80.91.4-0.9-1.0-1.1-0.8-1.2-0.7-0.80.81.0
Delay disc. indifference point, 8s delay0.20.30.5-0.3-0.7-0.6-0.3-0.7-0.3-0.5-0.00.6
Indifference point function ln k2.23.96.5-2.5-2.1-1.9-2.2-1.7-2.1-1.80.62.2
Indifference point function log k2.23.96.5-2.5-2.1-1.9-2.2-1.7-2.1-1.80.62.2
Patch foraging total patch changes 0 sec1.42.64.72.21.61.71.71.81.21.3-1.5-1.3
Patch foraging total patch changes 12 sec3.64.76.92.62.32.32.42.12.12.1-0.9-2.3
Patch foraging total patch changes 18 sec3.25.09.13.02.32.32.42.22.01.8-1.2-2.3
Patch foraging total patch changes 24 sec0.71.23.82.01.11.11.21.10.80.7-0.3-0.8
Patch foraging total patch changes 6 sec1.62.59.83.11.31.31.91.11.11.0-0.5-1.3
Patch foraging time to switch 0 sec0.00.10.30.2-0.00.10.5-0.20.30.50.3-0.4
Patch foraging water rate 0 sec0.10.10.4-0.2-0.1-0.2-0.60.0-0.5-0.60.00.4
Patch foraging water rate 12 sec0.10.20.5-0.7-0.10.0-0.50.2-0.4-0.3-0.70.3
Patch foraging water rate 18 sec0.00.00.1-0.10.10.20.00.2-0.00.20.0-0.1
Patch foraging water rate 24 sec0.40.60.8-0.6-0.7-0.7-0.8-0.7-0.9-0.80.80.5
Patch foraging water rate 6 sec0.71.13.7-1.9-0.6-0.6-1.4-0.1-0.9-1.1-0.01.2
Seeking ratio, delayed vs. immediate footshock0.10.20.60.1-0.20.10.4-0.10.70.8-0.2-0.3
Distance traveled before self-admin0.10.10.20.1-0.2-0.2-0.2-0.4-0.3-0.30.2-0.2
Distance traveled after self-admin0.10.10.7-0.80.20.1-0.30.00.20.1-0.30.2
Extensor digitorum longus weight6.826.634.6-4.1-5.3-5.6-5.0-5.9-5.3-5.15.93.8
Bone: elastic displacement1.01.23.01.20.90.81.10.61.01.3-1.7-0.4
Bone: elastic work0.30.42.20.60.10.10.6-0.00.40.7-1.50.4
Bone: endosteal estimation3.27.19.2-3.0-2.9-2.7-2.9-2.3-2.6-2.81.62.7
Bone: endosteal perimeter3.06.49.3-3.0-2.8-2.6-2.8-2.3-2.4-2.51.72.4
Epididymis fat weight0.41.56.4-0.41.11.30.41.61.00.8-2.5-0.3
Delta time in closed arm before/after self-admin0.60.51.7-1.3-0.4-0.4-0.9-0.4-0.6-0.80.70.5
Delta time in open arm before/after self-admin3.23.24.71.42.01.71.51.71.81.5-2.2-2.0
Diff in mean of infusions in LGA sessions0.10.10.6-0.8-0.3-0.2-0.4-0.1-0.3-0.10.5-0.3
Delay discount exponential model param0.80.91.70.81.11.10.91.30.71.0-0.9-0.7
Extinction: sum of active levers before priming4.54.96.8-1.9-2.4-2.3-2.3-2.0-2.6-2.41.52.4
Active lever presses in extinction session 60.90.91.6-1.0-1.3-1.0-0.8-1.0-0.9-0.60.31.1
Bone: final force3.25.26.5-2.4-2.5-2.3-2.5-2.1-2.5-2.31.22.3
Bone: final moment4.26.78.4-2.6-2.9-2.7-2.8-2.4-2.9-2.71.42.5
Food consumed during 24 hour testing period0.10.20.6-0.8-0.2-0.0-0.40.2-0.1-0.2-0.50.5
Glucose0.30.51.41.20.30.30.80.20.70.8-0.8-0.5
Heart weight0.20.32.0-1.4-0.3-0.1-0.50.20.1-0.1-0.20.4
Delay discount hyperbolic model param0.91.02.00.81.21.20.91.40.81.0-1.0-0.8
Intermittent access intake day 1-15 change0.00.10.2-0.2-0.2-0.2-0.3-0.2-0.2-0.2-0.30.4
Intermittent access intake escalation0.00.00.1-0.2-0.0-0.2-0.3-0.1-0.2-0.3-0.20.2
Intermittent access intake escalation 20.10.10.3-0.20.60.2-0.10.2-0.00.1-0.3-0.4
Intermitt. access day 1 inactive lever presses0.10.31.5-0.80.40.0-0.4-0.00.1-0.01.2-0.3
Intermitt. access day 15 inactive lever presses0.10.10.4-0.70.40.2-0.10.20.40.40.0-0.2
Intermitt. access escalation Index0.91.23.00.4-0.9-1.1-0.6-1.3-1.1-0.91.71.2
Intermittent access day 1 total infusions0.50.81.70.90.80.91.10.61.31.10.1-0.9
Intermittent access day 15 total infusions0.50.82.31.50.70.71.10.30.90.9-0.1-0.9
Intermittent access terminal intake (last 3 days)0.50.61.31.20.80.51.00.00.90.90.4-0.7
Intermittent access total infusions0.40.51.11.10.40.40.9-0.00.80.80.5-0.8
Intermittent access day 1 locomotion0.10.10.30.60.00.20.40.00.40.40.4-0.0
Intermittent access day 15 total locomotion0.10.20.7-0.8-0.2-0.3-0.5-0.3-0.0-0.1-0.50.3
Intermittent access total locomotion0.00.00.1-0.00.10.0-0.0-0.20.20.20.2-0.0
Intermittent access standard deviation0.61.32.51.00.91.01.20.81.21.4-1.2-1.6
Left kidney weight0.00.10.3-0.5-0.4-0.1-0.20.10.1-0.0-0.10.1
Right kidney weight0.21.11.6-1.2-1.2-1.0-1.3-0.7-1.1-1.20.40.9
Cocaine induced anxiety1.72.44.2-0.8-1.7-1.7-1.5-1.7-1.7-1.50.72.1
Post-drug Anxiety1.92.03.1-1.6-1.4-1.3-1.7-1.1-1.6-1.40.51.8
Baseline Anxiety0.80.92.0-0.50.91.10.51.40.90.9-0.8-1.4
Tail length0.31.02.91.70.50.81.20.70.91.1-1.2-0.1
Length with tail0.00.10.40.40.10.30.40.20.20.3-0.70.4
Length without tail0.20.82.2-1.5-0.7-0.8-1.1-0.8-0.9-0.80.40.7
Times rat made contact with spout0.30.40.7-0.8-0.4-0.3-0.8-0.1-0.7-0.8-0.30.5
Lifetime Intake0.30.30.60.80.50.40.70.00.70.70.6-0.4
Liver weight, left5.79.412.8-3.6-3.2-3.1-3.4-2.9-2.8-3.21.83.2
Liver weight, right0.30.61.7-1.3-0.6-0.7-1.0-0.6-0.7-0.80.20.6
Locomotor activity0.00.00.10.30.1-0.00.1-0.1-0.30.0-0.0-0.3
Locomotor testing distance0.10.10.60.80.10.00.3-0.1-0.20.0-0.3-0.1
Locomotor testing rearing0.10.20.40.6-0.2-0.20.0-0.2-0.5-0.3-0.40.5
Locomotion in novel chamber5.06.38.5-2.0-2.4-2.7-2.6-2.9-2.7-2.72.42.1
Locomotion in novel chamber post-restriction0.30.51.90.1-0.2-0.7-0.2-0.9-0.3-0.31.21.4
Fecal boli incidents, locomotor time 11.82.54.71.11.31.61.61.51.81.7-2.2-1.4
Change in fecal boli incidents, locomotor task0.80.81.2-0.4-0.9-0.9-0.9-0.8-1.1-1.11.01.0
Time >=10cm from walls, locomotor time 10.30.30.70.20.40.50.60.50.60.7-0.8-0.1
Bouts of movement, locomotor time 11.41.61.91.01.31.31.31.41.41.4-1.0-1.2
Total resting periods, locomotor time 12.32.53.31.31.61.71.61.81.61.6-1.6-1.4
Rest time, locomotor task time 10.40.51.81.30.00.40.80.50.50.5-0.90.2
Distance moved, locomotor task time 10.20.31.6-0.6-0.0-0.4-0.5-0.4-0.4-0.41.30.1
Vertical activity count, locomotor time 10.20.62.4-1.1-0.4-0.6-0.5-0.8-0.4-0.21.6-0.2
Time >=10cm from walls, locomotor time 20.10.10.20.40.10.10.3-0.10.10.3-0.30.5
Bouts of movement, locomotor time 20.91.52.8-0.7-1.4-1.3-1.1-1.4-1.3-1.01.70.9
Total resting periods, locomotor time 20.81.33.1-0.6-1.3-1.2-0.9-1.3-1.1-0.81.80.7
Rest time, locomotor task time 20.60.81.51.20.50.80.90.70.90.8-0.7-1.0
Distance moved, locomotor task time 20.00.10.3-0.00.60.0-0.10.1-0.3-0.20.10.2
Vertical activity count, locomotor time 20.30.40.7-0.4-0.6-0.8-0.5-0.9-0.8-0.50.70.4
Light reinforcement 11.12.73.81.91.51.71.91.71.61.8-0.8-1.7
Light reinforcement 22.03.14.52.12.01.82.01.61.51.8-1.1-1.7
Bone: marrow area3.26.99.1-3.0-2.9-2.7-2.9-2.3-2.6-2.71.62.6
Bone: maximum diameter1.01.93.3-1.8-1.6-1.4-1.5-1.3-1.2-1.21.31.0
Bone: maximum force3.05.37.6-2.0-2.7-2.5-2.2-2.3-2.4-2.21.62.4
Bone: maximum moment3.86.69.3-2.2-3.1-2.8-2.6-2.6-2.7-2.61.82.6
Mean time between licks in bursts0.20.52.71.70.30.40.60.30.00.1-0.8-0.3
Mean num. licks in bursts0.20.31.8-1.3-0.1-0.1-0.8-0.1-0.2-0.5-0.40.1
Cd content in liver0.10.10.20.30.40.20.3-0.00.40.5-0.2-0.2
Co content in liver0.80.91.5-0.4-1.1-1.2-0.7-1.1-0.9-0.80.71.2
Cu content in liver6.57.711.4-3.4-2.7-2.7-3.1-2.5-2.9-2.72.12.8
Fe content in liver0.30.41.00.2-0.8-0.7-0.4-0.8-0.7-0.50.31.0
K content in liver1.41.33.2-0.5-1.1-1.2-1.0-1.0-1.4-1.30.41.8
Mg content in liver1.11.12.4-0.4-1.1-1.1-1.0-0.9-1.3-1.20.21.6
Mn content in liver0.10.10.91.00.30.10.20.0-0.4-0.2-0.0-0.2
Na content in liver1.81.93.1-1.1-1.3-1.5-1.5-1.4-1.8-1.50.81.5
Rb content in liver2.02.35.3-1.2-1.8-1.7-1.3-1.7-1.2-1.20.92.3
Se content in liver0.30.30.70.70.50.50.60.50.40.7-0.80.1
Sr content in liver0.10.10.4-0.00.20.1-0.20.4-0.3-0.3-0.6-0.2
Zn content in liver0.80.91.40.21.01.00.71.21.00.9-1.2-0.7
Bone: minimum diameter2.24.17.2-2.7-2.0-2.0-2.3-1.8-2.0-1.91.71.5
Time in familiar zone, hab. session 10.10.10.50.20.10.20.20.20.20.3-0.7-0.0
Time in novel zone, hab. session 10.30.31.7-0.3-0.2-0.4-0.4-0.4-0.3-0.41.3-0.1
Total zone transitions, hab. session 11.21.63.11.31.11.21.41.11.31.4-0.2-1.8
Total locomotion distance, hab. session 12.94.15.51.72.02.21.92.32.02.0-1.7-2.3
Locomotion velocity, hab. session 12.02.83.81.61.61.81.61.91.61.6-1.6-1.8
Time in familiar zone, hab. session 21.92.02.6-1.3-1.4-1.5-1.5-1.5-1.5-1.60.51.6
Time in novel zone, hab. session 20.40.40.70.90.50.60.70.60.60.60.2-0.6
Total zone transitions, hab. session 21.41.72.21.31.21.21.51.21.51.5-1.2-1.3
Total locomotion distance, hab. session 22.63.34.91.31.81.91.82.21.91.8-1.9-1.8
Locomotion velocity, hab. session 22.43.24.71.21.71.91.72.21.91.8-2.1-1.7
Novel to familiar place preference ratio0.10.10.4-0.60.10.2-0.20.3-0.0-0.10.4-0.6
Novelty place preference0.10.10.2-0.4-0.10.0-0.20.2-0.1-0.20.4-0.4
Time in novel zone, NPP test0.10.10.3-0.6-0.10.0-0.30.1-0.3-0.30.5-0.4
Total zone transitions, NPP test5.27.59.23.02.62.73.02.72.82.8-2.1-2.8
Total locomotion distance, NPP test7.39.911.93.03.13.33.23.53.23.1-3.1-3.0
Locomotion velocity, NPP test7.210.212.83.03.13.33.23.63.23.1-3.3-2.9
Intraocular pressure0.10.20.60.70.60.20.5-0.00.40.50.10.1
Delta distance traveled before/after self-admin0.90.92.5-0.70.91.00.31.31.00.8-1.60.0
Delta ambulatory time before/after self-admin0.60.81.8-1.00.80.90.21.10.90.8-1.30.0
Parametrial fat weight0.30.71.20.80.90.90.71.00.80.7-1.1-0.1
Pavlov. Cond. lever latency0.60.71.70.41.00.90.60.90.90.7-1.3-0.6
Pavlov. Cond. magazine entry latency1.62.04.0-0.7-1.5-1.7-1.1-1.9-1.3-1.32.01.1
Pavlov. Cond. change in total contacts2.12.24.4-1.2-1.5-1.6-1.4-1.6-1.4-1.42.10.9
Pavlov. Cond. index score2.73.46.0-1.2-2.0-2.1-1.5-2.2-1.7-1.72.41.4
Pavlov. Cond. latency score2.63.35.8-1.2-2.0-2.0-1.5-2.1-1.8-1.62.41.4
Pavlov. Cond. lever contacts0.91.02.0-0.4-1.2-1.1-0.7-1.1-1.0-0.91.40.9
Pavlov. Cond. magazine entry number1.01.32.80.71.21.30.81.51.00.9-1.7-0.8
Pavlov. Cond. intertrial magazine entries3.44.05.81.62.42.21.82.21.91.9-1.7-2.2
Pavlov. Cond. lever-magazine prob. diff.2.73.35.9-1.0-2.0-2.1-1.4-2.2-1.7-1.62.41.5
Pavlov. Cond. response bias0.81.01.8-0.4-1.1-1.2-0.7-1.3-0.8-0.81.40.8
Pavlov. Cond. lever latency1.72.33.4-1.1-1.8-1.6-1.4-1.6-1.5-1.71.31.6
Pavlov. Cond. magazine entry latency3.23.84.71.82.12.01.91.91.92.0-2.2-1.6
Pavlov. Cond. change in total contacts0.10.20.7-0.30.60.30.10.20.20.30.7-0.9
Pavlov. Cond. index score2.73.75.01.62.22.01.82.01.92.0-1.8-1.9
Pavlov. Cond. latency score2.93.85.21.72.32.11.92.01.92.0-1.8-1.9
Pavlov. Cond. lever contacts2.33.14.31.22.11.91.61.91.71.9-1.7-1.8
Pavlov. Cond. magazine entry number1.51.82.7-1.0-1.6-1.5-1.3-1.4-1.4-1.41.31.3
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.0-0.3-0.0-0.10.1-0.1-0.1-0.70.5
Pavlov. Cond. lever-magazine prob. diff.2.22.94.21.42.01.81.61.71.71.8-1.5-1.8
Pavlov. Cond. response bias1.52.13.00.91.71.51.31.51.41.6-1.4-1.5
Time in closed arm before self-admin0.10.10.30.6-0.1-0.10.3-0.0-0.2-0.00.60.4
Time in closed arm after self-admin1.01.03.6-0.5-1.0-0.9-0.7-0.9-1.0-0.91.90.9
Time in open arm before self-admin1.61.72.7-1.0-1.3-1.4-1.1-1.7-1.1-1.01.61.4
Time in open arm after self-admin0.50.51.2-0.10.90.70.40.60.90.7-1.1-0.7
Bone: periosteal estimation3.88.011.9-3.5-3.1-2.9-3.1-2.6-2.8-2.72.02.6
Bone: periosteal perimeter3.56.08.1-2.8-2.7-2.6-2.6-2.4-2.4-2.32.12.1
Bone: post-yield work1.62.33.3-1.2-1.8-1.7-1.5-1.5-1.6-1.61.21.5
Progressive ratio test 1 active lever presses1.61.94.92.21.11.31.70.91.51.5-0.6-1.0
Progressive ratio test 1 breakpoint1.61.94.62.21.11.31.71.01.51.5-0.6-1.0
Progressive ratio test 1 inactive lever presses0.50.71.40.40.80.80.80.51.21.00.6-1.2
Progressive ratio test 2 active lever presses0.20.21.0-0.50.0-0.2-0.2-0.60.10.11.0-0.0
Progressive ratio test 2 breakpoint0.20.21.2-0.5-0.0-0.3-0.2-0.70.00.01.1-0.0
Progressive ratio test 2 inactive lever presses0.10.20.7-0.80.2-0.1-0.3-0.40.20.20.6-0.0
Incentive Sensitization - Responses1.01.33.3-1.8-0.7-1.1-1.2-1.3-0.8-1.01.30.7
Incentive Sensitization - Breakpoint1.21.63.6-1.9-0.8-1.2-1.3-1.4-0.9-1.11.50.7
Sum of active levers in priming session hrs 5-60.20.20.90.20.60.10.2-0.10.00.40.3-0.9
Progressive ratio0.00.10.20.1-0.4-0.2-0.0-0.3-0.0-0.10.4-0.4
Food seeking constrained by brief footshock0.40.51.1-0.00.90.80.70.61.01.10.2-0.1
Seeking ratio, punishment vs. effort0.20.30.80.00.90.70.40.60.60.7-0.10.1
Retroperitoneal fat weight1.25.18.82.12.42.42.02.52.12.2-3.0-1.3
Reaction time number correct0.40.71.4-0.3-1.2-0.9-0.8-0.7-0.8-0.9-0.51.2
Reaction time mean minus median0.20.61.10.61.00.80.80.60.90.8-0.0-1.1
Reaction time mean minus median AUC0.10.40.70.70.70.50.70.20.60.60.4-0.9
Reaction time num false alarms4.15.87.91.82.82.62.22.62.52.3-1.7-2.8
Reaction time num false alarms AUC4.06.39.21.92.92.72.42.52.72.5-1.5-3.0
Reaction time trials correct on left0.40.71.4-0.3-1.2-0.9-0.8-0.7-0.8-0.9-0.51.2
Reaction time trials on left0.30.61.1-0.3-1.0-0.7-0.7-0.6-0.7-0.8-0.51.0
Reaction time mean0.10.20.7-0.80.50.2-0.20.30.20.10.4-0.5
Reaction time mean AUC0.10.21.0-1.00.2-0.1-0.50.0-0.2-0.20.5-0.3
Median of all reaction times0.20.31.6-1.30.2-0.0-0.60.2-0.2-0.30.4-0.1
Reaction time omissions2.84.15.90.62.32.31.72.32.42.2-1.6-2.1
Reaction time false alarm rate3.85.28.91.52.82.52.22.32.42.3-0.8-3.0
Reaction time premature initiation rate0.40.61.1-0.01.01.00.60.91.00.9-0.7-0.1
Reaction time premature initiations0.10.20.8-0.20.30.40.00.40.40.3-0.90.6
Std. dev. reaction times0.30.51.60.20.90.70.50.60.70.70.2-1.3
Reaction time trials completed0.30.61.1-0.3-1.0-0.7-0.7-0.6-0.7-0.8-0.51.0
Reaction time trials AUC0.40.81.4-0.4-1.2-0.9-0.9-0.7-0.9-1.0-0.41.2
Run reversals in cocaine runway, females0.10.10.4-0.60.00.1-0.30.2-0.1-0.1-0.20.0
Run reversals in cocaine runway, males0.00.00.20.30.1-0.00.2-0.00.0-0.10.4-0.2
Latency to leave start box in cocaine runway0.20.20.4-0.60.0-0.3-0.5-0.3-0.4-0.50.60.6
Latency to leave start box in cocaine runway, F0.10.10.20.20.50.30.30.30.10.10.1-0.1
Latency to leave start box in cocaine runway, M1.11.02.0-1.4-0.6-0.9-1.2-1.0-0.9-1.10.90.9
Std. dev. time between licks in bursts0.50.62.41.60.40.50.70.60.10.3-1.3-0.1
Total sessions with >9 infusions0.30.31.00.40.50.40.70.11.00.80.6-0.2
Short access day 1 total inactive lever presses0.10.10.20.1-0.10.00.2-0.20.50.50.30.4
Short access day 10 total inactive lever presses0.10.21.0-1.00.3-0.0-0.5-0.00.10.10.70.0
Short access day 1 total infusions0.10.20.4-0.40.60.30.10.10.50.20.40.5
Short access day 10 total infusions0.60.81.41.00.90.81.10.51.21.00.4-0.9
Short access total infusions0.10.20.30.30.50.30.40.10.60.40.50.2
Short access day 1 locomotion0.00.00.2-0.20.1-0.0-0.2-0.10.2-0.00.50.0
Short access day 10 total locomotion0.00.10.2-0.30.10.20.10.20.50.30.3-0.3
Short access total locomotion0.20.20.50.40.40.30.50.20.70.60.4-0.3
One hour access (0.3 mA shock)2.32.63.8-1.5-1.7-1.7-1.5-1.9-1.4-1.32.01.3
Compulsive drug intake1.21.42.9-1.7-1.3-1.0-1.1-1.0-1.1-0.71.50.9
One hour access (shock baseline)0.60.91.6-0.6-0.8-1.0-0.8-1.3-0.8-0.91.20.8
Social response proportion1.51.72.50.51.31.41.21.21.61.6-1.3-1.3
Social responses1.72.22.61.21.41.51.61.51.61.6-1.4-1.5
Social time0.91.22.10.21.11.10.91.11.21.0-1.5-1.4
Soleus weight0.61.72.3-1.0-1.2-1.4-1.4-1.5-1.5-1.40.61.3
Bone: stiffness4.37.08.9-2.8-3.0-2.7-2.7-2.3-2.7-2.72.22.5
Tibialis anterior weight4.816.431.7-3.0-4.1-4.2-3.7-4.5-4.0-4.15.62.4
Time to tail flick, vehicle, before self-admin0.10.10.30.2-0.1-0.10.1-0.30.20.10.5-0.2
Time to tail flick, vehicle, after self-admin0.50.61.1-1.1-0.9-0.8-1.0-0.4-1.0-0.90.30.3
Time to tail flick, test, before self-admin1.71.73.41.31.41.31.41.11.41.1-0.4-1.9
Time to tail flick, test, after self-admin0.90.93.0-1.7-0.4-0.8-1.2-0.6-0.9-1.00.90.4
Delta time to tail flick, vehicle, before/after SA0.60.61.2-1.1-0.9-0.7-1.0-0.3-1.0-1.0-0.20.2
Delta time to tail flick, test, before/after SA1.51.64.5-2.1-1.0-1.0-1.5-0.7-1.2-1.00.61.4
Tibia length0.51.32.8-1.7-1.1-0.9-1.5-0.8-1.3-1.20.80.7
Ambulatory time before self-admin0.00.00.10.3-0.1-0.10.0-0.2-0.1-0.00.1-0.2
Ambulatory time after self-admin0.20.21.3-1.10.0-0.0-0.5-0.10.0-0.1-0.20.4
Bone: tissue strength2.12.12.8-0.7-1.6-1.6-1.4-1.7-1.5-1.61.61.2
Total heroin consumption2.42.83.9-2.0-1.7-1.8-1.8-1.8-1.8-1.41.01.7
Bone: trabecular number0.30.51.1-1.0-0.6-0.5-0.8-0.3-0.6-0.7-0.11.0
Bone: trabecular spacing0.10.10.9-0.00.20.00.0-0.2-0.00.10.9-0.4
Bone: trabecular thickness0.10.10.10.20.20.20.30.30.40.2-0.1-0.4
Bone: trabecular tissue density0.40.61.40.90.50.50.90.30.80.90.7-1.2
Water consumed over 24 hours0.20.30.7-0.1-0.6-0.4-0.6-0.2-0.8-0.8-0.30.7
Number of responses in last shaping day3.13.45.01.81.81.71.81.71.91.9-1.7-2.2