Znf740

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	IL	gene expression	Znf740	0.26	0.13	1.6e-03	0.09	0.04	0.07	0.09	4.4e-03	3.9e-02	1.1e-02	3.7e-03
2	Adipose	mRNA stability	Znf740	0.19	0.08	0.0e+00	0.16	0.16	0.16	0.17	2.7e-17	9.5e-18	7.5e-18	2.4e-18
3	OFC	gene expression	Znf740	0.29	0.14	2.0e-03	0.11	0.12	0.1	0.12	1.4e-03	8.6e-04	2.2e-03	8.9e-04
4	Liver	mRNA stability	Znf740	0.06	0.03	1.3e-04	0.04	0.03	0.03	0.04	1.2e-05	1.5e-04	9.9e-05	4.9e-05
5	PL	gene expression	Znf740	0.06	0.05	7.2e-05	0.04	0.04	0.03	0.04	1.2e-05	8.6e-05	1.0e-04	5.9e-05
6	Brain	gene expression	Znf740	0.28	0.11	2.8e-15	0.19	0.18	0.19	0.19	3.9e-17	1.2e-16	1.9e-17	3.7e-17
7	Adipose	gene expression	Znf740	0.38	0.13	0.0e+00	0.32	0.3	0.31	0.31	9.9e-36	1.2e-33	3.9e-35	3.2e-35
8	NAcc	gene expression	Znf740	0.09	0.02	2.2e-09	0.09	0.08	0.08	0.08	4.1e-10	2.6e-09	3.3e-09	1.5e-09
9	Liver	gene expression	Znf740	0.04	0.03	2.0e-03	0.02	0.01	0.01	0.02	1.9e-03	1.1e-02	9.9e-03	2.5e-03
10	Eye	isoform ratio	XM_008765870.3	0.28	0.18	8.1e-03	0.2	0.12	0.15	0.15	5.4e-04	6.7e-03	3.0e-03	2.7e-03
11	NAcc	mRNA stability	Znf740	0.08	0.03	1.2e-04	0.04	0.03	0.03	0.03	1.1e-05	1.3e-04	7.9e-05	1.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	1.6	2.7	4.4	-2.1	-1.9	-2.0	1.7	2.1	1.8	1.7	1.7	0.7	-0.7	0.5
Area under the delay curve	0.7	0.8	1.6	-0.8	-0.7	-1.0	0.9	0.5	0.6	0.6	0.7	1.3	-1.3	1.0
BMI with tail	1.3	4.2	7.6	-2.7	-2.3	-2.8	2.4	1.8	2.1	2.1	2.0	1.3	-1.3	1.3
BMI without tail	0.3	0.5	0.9	-0.5	-0.7	-0.7	0.9	0.6	0.7	0.9	0.9	-0.8	0.8	-0.3
Body weight	0.4	1.7	4.1	-1.8	-1.4	-2.0	1.2	1.2	1.4	1.4	1.2	0.6	-0.6	0.4
Weight adjusted by age	0.5	0.5	1.3	0.7	0.7	0.0	-0.9	-0.7	-0.8	-0.7	-1.2	-0.5	0.5	-0.5
Bone surface	3.4	6.0	9.5	-3.1	-2.7	-2.6	2.6	2.9	2.6	2.6	2.6	1.6	-1.6	1.2
Bone volume	2.9	5.0	7.6	-2.8	-2.5	-2.3	2.4	2.8	2.4	2.5	2.4	1.3	-1.3	0.8
Breakpoint value in progressive ratio session	2.9	3.2	5.5	-2.3	-2.0	-1.4	2.2	1.7	1.8	2.1	1.7	1.5	-1.5	1.1
Number of licking bursts	0.4	0.5	1.8	1.3	0.3	1.0	0.2	-0.3	-0.2	0.1	-0.1	-1.0	1.0	-0.6
Context. condit. distance diff. score	0.5	0.6	1.3	-1.1	-0.9	-0.3	1.0	0.8	0.9	1.0	0.9	0.1	-0.1	-0.2
Locomotion velocity, session 1	6.2	6.7	12.4	3.5	2.5	2.9	-2.1	-2.4	-2.3	-2.0	-2.0	-3.0	3.0	-2.5
Locomotion distance, session 1	4.4	5.6	9.5	3.1	2.4	2.5	-2.1	-2.7	-2.2	-1.9	-1.9	-2.4	2.4	-2.4
Locomotion velocity, session 2	3.1	3.6	6.7	2.6	1.6	1.7	-1.1	-1.7	-1.4	-1.1	-1.1	-2.6	2.6	-2.5
Locomotion distance, session 2	4.6	6.5	8.5	2.9	2.7	2.7	-2.5	-2.8	-2.5	-2.4	-2.4	-2.2	2.2	-2.3
Locomotion velocity, session 3	3.2	3.7	5.7	2.4	1.8	2.3	-1.4	-1.8	-1.6	-1.4	-1.4	-2.1	2.1	-2.4
Locomotion distance, session 3	2.4	2.6	7.1	1.1	1.2	1.8	-0.9	-1.1	-1.1	-1.0	-1.0	-2.3	2.3	-2.7
Stereotopy head waving bouts, day 3	0.8	0.9	1.5	-0.5	-0.9	-0.8	0.9	0.8	1.0	1.0	1.1	1.0	-1.0	1.2
Stereotopy head waving duration, day 3	0.3	0.3	0.8	0.3	-0.4	-0.4	0.5	0.3	0.6	0.7	0.7	0.7	-0.7	0.9
Locomotion velocity, session 7	1.0	1.1	2.7	1.6	1.2	1.6	-0.9	-1.1	-1.2	-1.0	-1.0	-0.2	0.2	-0.1
Locomotion distance, session 7	1.8	2.3	3.3	1.7	1.7	1.8	-1.5	-1.7	-1.7	-1.6	-1.6	-0.9	0.9	-1.1
Stereotopy head waving bouts, day 7	0.6	0.7	1.9	-0.3	-0.8	-0.9	0.6	0.9	0.8	0.6	0.7	0.9	-0.9	1.4
Stereotopy head waving duration, day 7	1.7	2.0	4.1	-0.8	-1.4	-1.4	1.3	1.5	1.3	1.3	1.3	1.6	-1.6	2.0
Locomotion velocity, session 8	0.1	0.2	1.0	1.0	0.1	0.5	0.3	-0.4	-0.1	0.1	0.1	-0.2	0.2	-0.2
Locomotion distance, session 8	2.2	3.3	6.2	1.9	1.7	2.1	-1.4	-1.8	-1.5	-1.3	-1.3	-2.0	2.0	-2.5
Degree of sensitization distance	0.5	0.5	1.9	0.2	0.2	-0.3	-0.1	-0.3	-0.2	-0.2	-0.3	1.2	-1.2	1.4
Degree of sensitization stereotypy	1.1	1.2	2.6	-0.7	-1.1	-1.1	0.9	1.1	1.0	0.9	1.0	1.2	-1.2	1.6
Conditioned locomotion	1.0	1.1	2.6	0.4	0.9	1.0	-0.9	-1.1	-0.9	-0.8	-0.8	-1.3	1.3	-1.6
Cocaine response after cond. corrected	1.1	1.3	2.2	1.4	1.4	1.2	-1.0	-1.1	-1.5	-1.3	-1.3	-0.3	0.3	-1.0
Cocaine response after cond. not corrected	1.2	1.3	2.1	1.2	1.3	1.1	-1.2	-0.9	-1.5	-1.4	-1.4	-0.4	0.4	-0.9
Cocaine response before conditioning	0.1	0.1	0.2	-0.3	0.0	0.2	-0.4	0.4	-0.0	-0.3	-0.3	-0.0	0.0	0.4
Saline control response	0.5	0.7	2.0	-0.3	0.4	0.9	-0.5	-0.4	-0.5	-0.6	-0.8	-1.4	1.4	-1.1
Bone: connectivity density	0.2	0.3	1.1	-1.1	-0.6	-0.7	0.2	0.9	0.5	0.3	0.3	0.3	-0.3	0.0
Bone: cortical apparent density	0.6	0.9	1.5	1.2	1.2	0.8	-1.0	-1.2	-1.2	-1.0	-1.0	-0.2	0.2	0.0
Bone: cortical area	1.2	1.8	7.1	-2.7	-1.5	-1.6	1.4	1.2	1.3	1.0	1.1	0.7	-0.7	0.5
Bone: cortical porosity	0.3	0.3	1.0	-0.3	0.1	0.2	-0.3	-0.3	-0.2	-0.3	-0.5	-1.0	1.0	-0.8
Bone: cortical porosity	0.7	0.7	1.8	-0.2	0.5	0.5	-0.7	-0.6	-0.5	-0.7	-0.8	-1.3	1.3	-1.2
Bone: cortical thickness	0.2	0.3	1.3	-1.2	-0.2	-0.7	0.3	-0.1	0.1	-0.1	0.0	0.6	-0.6	0.6
Bone: cortical thickness	2.5	2.9	4.9	1.0	1.9	1.1	-2.2	-1.9	-2.1	-2.2	-2.2	-1.1	1.1	-1.1
Bone: cortical tissue density	0.8	1.0	1.8	1.3	1.3	0.9	-1.1	-1.3	-1.3	-1.1	-1.1	-0.3	0.3	-0.1
Condit. Reinf. active minus inactive responses	1.0	1.1	1.8	0.3	0.9	0.8	-1.4	-0.7	-0.9	-1.2	-1.1	-1.3	1.3	-1.1
Condit. Reinf. active-inactive response ratio	0.4	0.4	0.8	-0.2	0.5	0.4	-0.9	-0.3	-0.6	-0.9	-0.8	-0.8	0.8	-0.7
Condit. Reinf. active responses	2.4	2.9	4.3	1.1	1.6	1.5	-1.8	-1.6	-1.5	-1.6	-1.7	-2.1	2.1	-2.0
Condit. Reinf. inactive responses	3.1	3.6	5.1	2.1	2.0	1.9	-1.7	-2.3	-1.8	-1.6	-1.7	-1.9	1.9	-1.9
Incentive salience index mean	0.7	0.8	1.7	0.3	0.7	0.7	-0.9	-0.6	-0.7	-0.9	-0.8	-1.3	1.3	-1.1
Condit. Reinf. lever presses	0.1	0.1	0.4	0.3	0.0	0.1	0.1	-0.4	-0.0	0.0	-0.0	-0.6	0.6	-0.4
Condit. Reinf. active minus inactive responses	1.0	1.3	3.6	-1.1	-0.8	-0.9	0.9	0.3	0.7	0.7	0.6	1.9	-1.9	1.3
Condit. Reinf. active-inactive response ratio	1.0	1.0	2.6	-1.1	-0.8	-1.0	0.9	0.3	0.7	0.7	0.6	1.6	-1.6	1.0
Condit. Reinf. active responses	0.7	1.0	2.5	-1.0	-0.8	-0.6	0.8	0.5	0.8	0.8	0.7	1.6	-1.6	1.3
Condit. Reinf. inactive responses	0.1	0.1	0.3	0.4	0.3	0.6	-0.3	-0.0	-0.2	-0.2	-0.1	-0.5	0.5	-0.0
Condit. Reinf. lever presses	0.3	0.3	0.7	0.1	0.7	0.7	-0.6	-0.9	-0.7	-0.7	-0.8	0.1	-0.1	-0.2
Condit. Reinf. lever reinforcers received	0.3	0.5	1.7	-0.6	-0.3	-0.2	0.4	0.0	0.3	0.3	0.2	1.3	-1.3	0.9
Conditioned reinforcement - actives	1.2	1.2	4.8	1.0	0.2	0.3	0.3	-0.3	-0.4	0.0	-0.2	2.2	-2.2	1.3
Conditioned reinforcement - inactives	1.1	1.3	2.6	0.3	1.3	0.8	-1.3	-1.6	-1.5	-1.6	-1.5	0.2	-0.2	0.3
Conditioned locomotion	0.8	1.0	3.6	0.2	-0.2	-0.0	0.7	-0.1	0.1	0.6	0.2	1.9	-1.9	1.5
Patch foraging indifference point 0 sec	1.5	2.4	4.0	1.6	1.3	2.0	-1.0	-1.1	-1.3	-1.3	-1.3	-2.0	2.0	-1.6
Patch foraging indifference point AUC	1.6	1.8	2.6	1.5	1.5	1.4	-1.4	-1.6	-1.3	-1.4	-1.4	-1.0	1.0	-1.1
Delay disc. indifference point, 0s delay	0.1	0.2	0.5	0.3	0.1	-0.5	0.1	-0.4	-0.1	-0.1	-0.1	0.6	-0.6	0.7
Delay disc. indifference point, 16s delay	0.4	0.4	1.1	-1.0	-0.5	-0.8	0.4	0.1	0.3	0.0	0.2	0.9	-0.9	0.9
Delay disc. indifference point, 2s delay	3.5	3.9	7.5	-1.3	-1.7	-1.8	2.0	1.6	1.6	1.9	1.8	2.4	-2.4	2.7
Delay disc. indifference point, 24s delay	0.5	0.5	0.9	-0.6	-0.7	-0.7	0.6	0.6	0.5	0.6	0.5	0.9	-0.9	0.5
Delay disc. indifference point, 4s delay	0.9	0.9	1.6	-0.9	-0.9	-1.0	1.1	0.7	0.8	0.8	0.9	1.3	-1.3	1.0
Delay disc. indifference point, 8s delay	0.2	0.3	0.4	-0.5	-0.4	-0.5	0.7	0.3	0.4	0.6	0.5	0.6	-0.6	0.5
Indifference point function ln k	3.1	4.3	7.3	-2.3	-2.5	-2.2	2.7	2.3	2.3	2.5	2.2	0.8	-0.8	0.7
Indifference point function log k	3.1	4.3	7.3	-2.3	-2.5	-2.2	2.7	2.3	2.3	2.5	2.2	0.8	-0.8	0.7
Patch foraging total patch changes 0 sec	1.9	3.1	5.7	1.8	1.4	2.2	-1.2	-1.2	-1.5	-1.4	-1.4	-2.4	2.4	-2.0
Patch foraging total patch changes 12 sec	3.3	4.2	6.2	2.0	2.3	2.5	-2.4	-1.9	-2.2	-2.4	-2.1	-1.5	1.5	-1.5
Patch foraging total patch changes 18 sec	4.2	5.4	8.5	2.7	2.4	2.9	-2.3	-2.1	-2.1	-2.3	-2.1	-2.2	2.2	-2.2
Patch foraging total patch changes 24 sec	1.1	1.4	2.6	1.0	1.0	1.6	-1.1	-0.9	-0.8	-1.1	-0.9	-1.5	1.5	-1.3
Patch foraging total patch changes 6 sec	1.5	2.2	4.9	2.2	1.6	1.9	-1.4	-1.3	-1.5	-1.7	-1.4	-0.9	0.9	-0.9
Patch foraging time to switch 0 sec	0.4	0.6	2.5	0.6	0.3	-0.1	-0.3	-0.0	-0.5	-0.3	-0.5	1.3	-1.3	1.6
Patch foraging water rate 0 sec	0.2	0.4	1.3	-0.7	-0.5	-0.0	0.3	0.3	0.5	0.2	0.3	-0.9	0.9	-1.1
Patch foraging water rate 12 sec	0.3	0.5	1.5	-1.0	-0.5	-0.1	0.7	-0.0	0.5	0.2	0.0	-0.9	0.9	-1.2
Patch foraging water rate 18 sec	0.1	0.1	0.4	-0.6	-0.4	0.0	0.3	0.3	0.2	-0.1	0.1	-0.0	0.0	-0.4
Patch foraging water rate 24 sec	0.4	0.6	1.4	-0.9	-0.9	-0.6	1.2	0.6	0.9	0.7	0.8	0.6	-0.6	-0.0
Patch foraging water rate 6 sec	1.1	1.6	4.3	-2.1	-1.5	-0.8	0.8	1.2	1.5	1.1	1.2	-0.7	0.7	-1.5
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.4	-0.1	0.3	-0.1	-0.1	-0.6	-0.3	-0.0	0.3	0.1	-0.1	0.6
Distance traveled before self-admin	0.2	0.2	1.1	0.0	-0.0	0.0	0.2	0.0	-0.1	-0.0	-0.1	1.1	-1.1	0.7
Distance traveled after self-admin	0.4	0.5	1.4	-1.2	-0.2	-0.1	0.0	-0.2	-0.1	-0.4	-0.2	1.1	-1.1	1.1
Extensor digitorum longus weight	7.0	27.5	37.0	-4.6	-5.3	-6.1	5.5	4.6	5.2	5.3	4.9	5.2	-5.2	5.5
Bone: elastic displacement	1.4	1.5	3.0	1.7	1.5	1.6	-1.1	-1.7	-1.4	-1.1	-1.1	-0.7	0.7	-0.3
Bone: elastic work	0.3	0.4	1.5	0.7	0.8	0.4	-0.4	-1.2	-0.8	-0.6	-0.6	-0.4	0.4	0.0
Bone: endosteal estimation	2.7	5.9	10.7	-3.3	-3.0	-2.4	2.7	3.0	2.9	2.7	2.6	0.7	-0.7	0.2
Bone: endosteal perimeter	2.6	5.3	10.5	-3.2	-2.7	-2.4	2.4	2.7	2.6	2.5	2.5	1.1	-1.1	0.4
Epididymis fat weight	0.9	2.0	4.3	0.4	1.2	0.7	-1.6	-1.3	-1.2	-1.6	-1.4	-1.7	1.7	-2.1
Delta time in closed arm before/after self-admin	0.2	0.2	1.4	-1.2	-0.5	-0.3	0.0	0.5	0.5	-0.0	0.2	-0.2	0.2	0.1
Delta time in open arm before/after self-admin	3.1	3.0	5.7	2.1	1.8	1.6	-1.7	-1.8	-1.9	-1.5	-2.4	-1.2	1.2	-1.5
Diff in mean of infusions in LGA sessions	0.2	0.2	1.0	-0.5	-0.4	-1.0	0.3	0.2	0.3	0.2	0.2	0.4	-0.4	0.5
Delay discount exponential model param	1.2	1.3	2.3	1.1	1.0	1.2	-1.2	-0.8	-0.9	-0.9	-1.0	-1.5	1.5	-1.3
Extinction: sum of active levers before priming	3.1	3.1	4.7	-1.9	-2.1	-1.8	2.0	2.1	2.1	2.2	2.2	0.2	-0.2	0.4
Active lever presses in extinction session 6	1.2	1.2	3.3	-0.9	-1.0	-0.8	1.6	0.8	1.1	1.8	1.5	0.5	-0.5	0.2
Bone: final force	2.7	4.3	8.3	-2.9	-2.4	-2.4	2.1	2.5	2.3	2.1	2.1	1.1	-1.1	0.6
Bone: final moment	3.6	5.9	11.2	-3.4	-2.8	-2.7	2.5	2.8	2.7	2.6	2.5	1.2	-1.2	0.7
Food consumed during 24 hour testing period	0.2	0.3	0.6	-0.7	-0.4	-0.1	0.0	0.7	0.3	0.2	0.2	-0.8	0.8	-0.8
Glucose	0.2	0.2	0.9	0.4	0.5	0.0	-0.3	-0.9	-0.5	-0.6	-0.8	0.0	-0.0	0.3
Heart weight	0.2	0.2	0.9	-0.4	0.3	0.1	-0.9	-0.2	-0.5	-0.8	-0.6	0.4	-0.4	-0.0
Delay discount hyperbolic model param	1.6	1.7	3.0	1.1	1.1	1.3	-1.4	-0.9	-1.0	-1.0	-1.1	-1.7	1.7	-1.5
Intermittent access intake day 1-15 change	0.3	0.3	0.6	-0.4	-0.5	-0.2	0.7	0.4	0.5	0.6	0.6	0.8	-0.8	0.3
Intermittent access intake escalation	0.4	0.4	0.7	-0.4	-0.6	-0.1	0.8	0.6	0.7	0.7	0.8	0.7	-0.7	0.2
Intermittent access intake escalation 2	0.4	0.4	1.0	-0.5	-0.7	-0.2	0.9	0.6	0.7	1.0	0.6	0.6	-0.6	-0.1
Intermitt. access day 1 inactive lever presses	0.6	0.6	2.3	-1.2	-0.3	-0.6	-0.4	0.0	-0.0	-1.0	-0.2	0.7	-0.7	1.5
Intermitt. access day 15 inactive lever presses	0.3	0.4	1.2	-0.3	0.5	0.2	-0.8	-0.6	-0.7	-1.1	-0.9	0.1	-0.1	-0.3
Intermitt. access escalation Index	1.2	1.1	4.2	0.1	-0.6	-0.3	1.1	0.8	0.7	0.9	0.6	1.3	-1.3	2.0
Intermittent access day 1 total infusions	0.5	0.6	1.0	0.6	0.9	1.0	-0.7	-1.0	-1.0	-0.9	-0.8	0.5	-0.5	0.2
Intermittent access day 15 total infusions	0.4	0.5	1.1	0.9	0.6	1.0	-0.0	-0.6	-0.6	-0.2	-0.4	1.0	-1.0	0.3
Intermittent access terminal intake (last 3 days)	0.7	0.8	3.0	0.4	0.3	0.7	0.4	-0.4	-0.3	0.2	-0.3	1.7	-1.7	1.1
Intermittent access total infusions	0.6	0.7	2.9	0.3	0.2	0.7	0.3	-0.3	-0.3	-0.1	-0.1	1.7	-1.7	0.8
Intermittent access day 1 locomotion	0.4	0.4	1.1	0.7	0.6	1.1	-0.7	-0.7	-0.7	-1.0	-0.4	0.1	-0.1	-0.0
Intermittent access day 15 total locomotion	0.1	0.2	0.4	-0.5	-0.3	-0.1	0.4	0.2	0.3	0.3	0.4	0.6	-0.6	0.1
Intermittent access total locomotion	0.3	0.3	1.5	0.0	-0.0	0.4	0.1	0.0	-0.0	-0.3	-0.0	1.2	-1.2	0.7
Intermittent access standard deviation	0.3	0.3	1.1	0.7	0.6	0.5	-0.2	-0.7	-0.5	-0.2	-0.2	0.0	-0.0	-1.0
Left kidney weight	0.3	0.7	2.3	-1.5	-1.0	-1.2	0.7	0.8	0.9	0.9	0.7	0.4	-0.4	0.4
Right kidney weight	1.0	2.9	4.6	-2.0	-1.9	-2.1	1.7	1.8	1.8	1.7	1.5	1.2	-1.2	1.5
Cocaine induced anxiety	2.6	3.0	4.5	-1.1	-1.6	-1.3	1.9	1.5	1.6	1.7	1.8	2.1	-2.1	2.0
Post-drug Anxiety	4.9	5.5	6.8	-2.4	-2.5	-2.3	2.3	2.4	2.5	2.0	2.6	2.2	-2.2	2.3
Baseline Anxiety	0.4	0.4	0.9	-0.9	0.1	-0.2	-0.6	-0.3	-0.2	-0.7	-0.2	-0.9	0.9	-1.0
Tail length	0.2	0.7	1.3	1.1	0.8	0.8	-0.9	-0.5	-0.6	-0.3	-0.5	-1.1	1.1	-0.8
Length with tail	0.0	0.1	0.3	0.1	0.2	-0.3	-0.5	-0.1	-0.2	-0.1	-0.3	0.1	-0.1	-0.1
Length without tail	0.3	0.7	2.0	-1.1	-0.5	-1.1	0.2	0.4	0.3	0.1	0.0	1.4	-1.4	0.7
Times rat made contact with spout	0.3	0.4	0.6	-0.1	-0.6	-0.1	0.7	0.5	0.7	0.7	0.7	-0.6	0.6	-0.6
Lifetime Intake	0.4	0.4	1.4	0.2	0.2	0.8	-0.0	-0.3	-0.4	-0.3	-0.3	1.2	-1.2	0.7
Liver weight, left	0.9	1.5	2.9	-1.2	-1.4	-1.1	1.7	1.0	1.4	1.4	1.3	1.0	-1.0	0.4
Liver weight, right	0.3	0.5	1.8	-1.4	-0.8	-0.6	0.8	0.5	0.8	0.6	0.6	-0.0	0.0	-0.2
Locomotor activity	0.0	0.0	0.2	0.3	0.1	0.1	-0.0	-0.1	-0.2	-0.2	-0.3	-0.1	0.1	0.4
Locomotor testing distance	0.2	0.4	1.0	1.0	0.6	0.8	-0.4	-0.7	-0.6	-0.6	-0.6	-0.5	0.5	0.2
Locomotor testing rearing	0.1	0.1	0.5	0.7	-0.2	-0.1	0.5	0.2	0.3	0.5	0.4	-0.3	0.3	-0.0
Locomotion in novel chamber	2.9	3.6	5.4	-1.5	-1.8	-2.1	2.3	1.6	1.8	2.1	1.8	1.6	-1.6	2.3
Locomotion in novel chamber post-restriction	0.9	1.0	3.2	-0.9	-1.0	-0.8	1.0	1.0	0.9	1.0	0.6	1.0	-1.0	1.8
Fecal boli incidents, locomotor time 1	2.3	2.5	3.9	1.3	1.6	2.0	-1.4	-1.4	-1.6	-1.3	-1.4	-1.6	1.6	-2.0
Change in fecal boli incidents, locomotor task	0.9	0.8	1.2	-0.5	-1.0	-1.1	0.7	1.1	1.0	0.8	1.1	0.6	-0.6	1.0
Time >=10cm from walls, locomotor time 1	0.5	0.5	0.8	0.5	0.7	0.9	-0.6	-0.5	-0.6	-0.3	-0.7	-0.9	0.9	-0.9
Bouts of movement, locomotor time 1	1.3	1.4	2.3	1.3	1.4	1.3	-1.3	-1.5	-1.4	-1.2	-1.2	-0.7	0.7	-0.7
Total resting periods, locomotor time 1	2.3	2.6	3.4	1.8	1.8	1.7	-1.8	-1.7	-1.7	-1.6	-1.6	-1.4	1.4	-1.2
Rest time, locomotor task time 1	0.3	0.3	1.4	1.2	0.5	0.8	-0.4	-0.2	-0.5	-0.3	-0.1	-0.5	0.5	-0.3
Distance moved, locomotor task time 1	0.3	0.3	1.0	-0.9	-0.5	-0.5	0.5	0.3	0.5	0.2	0.2	0.6	-0.6	1.0
Vertical activity count, locomotor time 1	1.2	1.2	3.4	-1.0	-0.6	-1.0	0.9	0.1	0.5	0.7	0.5	1.8	-1.8	1.8
Time >=10cm from walls, locomotor time 2	0.1	0.1	0.2	0.4	0.3	0.4	0.0	-0.3	-0.2	0.2	-0.1	-0.2	0.2	0.0
Bouts of movement, locomotor time 2	1.2	1.3	2.0	-0.8	-1.0	-1.1	1.3	0.9	1.0	1.2	1.4	1.3	-1.3	1.3
Total resting periods, locomotor time 2	1.2	1.2	1.9	-0.7	-0.8	-1.0	1.2	0.7	0.9	1.1	1.3	1.4	-1.4	1.4
Rest time, locomotor task time 2	0.7	0.8	2.0	1.4	1.0	1.1	-0.9	-0.6	-0.9	-0.9	-0.5	-0.7	0.7	-0.9
Distance moved, locomotor task time 2	0.1	0.1	0.3	-0.3	-0.1	-0.4	0.0	-0.2	0.1	-0.2	-0.5	0.0	-0.0	0.5
Vertical activity count, locomotor time 2	0.8	0.8	1.8	-0.5	-0.6	-0.9	1.0	0.4	0.6	0.8	0.7	1.3	-1.3	1.3
Light reinforcement 1	2.2	4.0	5.1	2.0	2.1	2.3	-1.9	-1.9	-2.0	-1.7	-2.0	-2.0	2.0	-2.0
Light reinforcement 2	1.9	2.5	4.6	1.7	1.9	1.4	-1.9	-1.8	-1.8	-1.5	-2.2	-0.9	0.9	-1.0
Bone: marrow area	2.7	5.9	10.9	-3.3	-3.0	-2.4	2.7	3.0	2.9	2.7	2.6	0.7	-0.7	0.2
Bone: maximum diameter	0.6	1.1	4.7	-2.2	-1.1	-0.9	1.0	1.1	1.0	0.8	0.8	0.5	-0.5	0.3
Bone: maximum force	2.9	5.1	9.0	-3.0	-2.6	-2.5	2.5	2.3	2.4	2.4	2.3	1.4	-1.4	0.8
Bone: maximum moment	3.8	6.6	11.9	-3.5	-3.0	-2.9	2.9	2.6	2.9	2.8	2.8	1.4	-1.4	0.9
Mean time between licks in bursts	0.6	0.8	5.2	2.3	0.8	1.2	-0.2	-0.7	-0.6	-0.2	-0.2	-0.6	0.6	0.0
Mean num. licks in bursts	0.3	0.4	1.5	-1.2	-0.6	-1.0	0.2	0.6	0.5	0.2	0.4	0.6	-0.6	0.1
Cd content in liver	0.2	0.2	0.4	0.4	0.3	0.3	-0.3	-0.1	-0.4	-0.5	-0.5	0.7	-0.7	0.7
Co content in liver	1.0	1.2	2.0	-0.7	-1.3	-0.9	1.4	1.4	1.3	1.3	1.3	0.5	-0.5	0.6
Cu content in liver	7.1	8.5	10.8	-3.2	-3.3	-2.3	3.2	3.3	3.2	3.0	3.1	2.5	-2.5	2.3
Fe content in liver	0.2	0.2	0.7	0.9	0.6	0.6	-0.5	-0.5	-0.5	-0.4	-0.4	-0.2	0.2	0.1
K content in liver	0.3	0.3	0.6	0.4	-0.4	0.1	0.6	0.3	0.6	0.7	0.8	-0.6	0.6	-0.6
Mg content in liver	0.3	0.3	0.5	0.6	-0.1	0.5	0.6	-0.0	0.4	0.5	0.5	-0.7	0.7	-0.6
Mn content in liver	0.1	0.1	0.4	0.5	0.1	-0.2	0.0	-0.6	0.1	0.3	0.2	-0.1	0.1	0.2
Na content in liver	0.2	0.2	0.5	0.3	-0.2	0.1	0.5	0.1	0.5	0.7	0.6	0.4	-0.4	0.3
Rb content in liver	0.9	1.1	2.2	-1.1	-1.3	-0.1	1.5	1.1	1.3	1.2	1.4	0.6	-0.6	0.4
Se content in liver	0.8	0.9	1.5	1.2	1.2	1.0	-1.1	-1.0	-1.2	-1.1	-1.1	-0.1	0.1	-0.3
Sr content in liver	0.7	0.6	2.3	-0.1	0.3	0.5	-0.2	-0.2	-0.2	-0.0	-0.1	-1.5	1.5	-1.3
Zn content in liver	2.4	2.7	4.7	0.9	1.4	2.0	-1.4	-1.3	-1.4	-1.4	-1.4	-2.2	2.2	-1.9
Bone: minimum diameter	2.3	4.2	11.7	-3.4	-2.4	-2.4	2.2	2.1	2.1	1.8	1.8	1.0	-1.0	0.9
Time in familiar zone, hab. session 1	0.2	0.2	0.3	0.5	0.4	0.1	-0.5	-0.2	-0.4	-0.5	-0.5	-0.2	0.2	-0.2
Time in novel zone, hab. session 1	0.4	0.4	0.6	-0.7	-0.6	-0.4	0.7	0.3	0.6	0.6	0.6	0.7	-0.7	0.8
Total zone transitions, hab. session 1	1.3	1.8	3.4	1.5	1.5	1.5	-1.3	-1.9	-1.5	-1.3	-1.3	-0.8	0.8	-0.9
Total locomotion distance, hab. session 1	3.2	4.5	6.5	1.8	2.2	2.2	-2.0	-2.6	-2.0	-2.0	-2.0	-2.1	2.1	-2.3
Locomotion velocity, hab. session 1	2.3	3.3	4.8	1.7	1.8	1.9	-1.6	-2.1	-1.6	-1.6	-1.5	-1.9	1.9	-2.2
Time in familiar zone, hab. session 2	1.4	1.5	2.3	-1.4	-1.4	-1.5	1.2	1.4	1.4	1.2	1.2	0.8	-0.8	1.0
Time in novel zone, hab. session 2	0.3	0.2	0.6	0.7	0.6	0.7	-0.3	-0.8	-0.5	-0.3	-0.3	-0.4	0.4	-0.3
Total zone transitions, hab. session 2	2.0	2.6	3.2	1.7	1.7	1.7	-1.6	-1.8	-1.6	-1.6	-1.5	-1.4	1.4	-1.5
Total locomotion distance, hab. session 2	3.7	4.9	9.0	1.7	2.0	2.0	-2.0	-1.9	-1.9	-1.9	-1.9	-2.8	2.8	-3.0
Locomotion velocity, hab. session 2	3.7	4.9	9.5	1.7	2.0	2.0	-2.0	-1.8	-1.9	-1.9	-1.9	-2.8	2.8	-3.1
Novel to familiar place preference ratio	0.1	0.1	0.7	-0.8	-0.4	-0.4	0.1	0.5	0.3	0.2	0.2	-0.2	0.2	-0.1
Novelty place preference	0.1	0.2	0.4	-0.6	-0.4	-0.4	0.2	0.5	0.4	0.3	0.3	-0.4	0.4	-0.2
Time in novel zone, NPP test	0.2	0.2	0.5	-0.7	-0.5	-0.5	0.2	0.7	0.5	0.5	0.5	-0.2	0.2	-0.0
Total zone transitions, NPP test	5.8	8.2	10.3	3.2	3.1	3.1	-3.1	-3.1	-3.0	-2.8	-2.8	-2.3	2.3	-2.4
Total locomotion distance, NPP test	8.4	11.5	13.8	3.4	3.4	3.2	-3.4	-3.3	-3.2	-3.1	-3.1	-3.6	3.6	-3.7
Locomotion velocity, NPP test	8.7	12.3	16.5	3.4	3.4	3.3	-3.4	-3.3	-3.3	-3.2	-3.2	-4.0	4.0	-4.1
Intraocular pressure	0.4	0.5	1.9	0.2	0.2	0.5	-0.3	-0.3	-0.2	-0.4	-0.2	1.2	-1.2	1.4
Delta distance traveled before/after self-admin	0.7	0.7	1.7	-0.9	0.3	0.5	-0.9	-0.7	-0.5	-0.8	-0.7	-1.3	1.3	-0.9
Delta ambulatory time before/after self-admin	0.6	0.6	1.2	-1.1	0.3	0.5	-0.8	-0.7	-0.5	-0.9	-0.8	-1.0	1.0	-0.8
Parametrial fat weight	3.1	6.1	8.9	2.2	2.3	2.8	-2.5	-2.4	-2.1	-2.1	-2.2	-2.7	2.7	-3.0
Pavlov. Cond. lever latency	0.4	0.5	0.9	0.5	0.7	0.1	-0.9	-0.5	-0.7	-0.8	-0.7	0.9	-0.9	0.3
Pavlov. Cond. magazine entry latency	1.6	2.1	4.6	-1.2	-1.5	-1.5	1.5	1.2	1.3	1.1	1.1	1.5	-1.5	2.2
Pavlov. Cond. change in total contacts	1.5	1.6	2.3	-1.4	-1.5	-1.3	1.4	1.2	1.5	1.3	1.2	0.9	-0.9	1.1
Pavlov. Cond. index score	1.8	2.3	3.7	-1.4	-1.9	-1.6	1.9	1.5	1.7	1.6	1.5	0.8	-0.8	1.5
Pavlov. Cond. latency score	1.7	2.2	3.8	-1.5	-1.9	-1.4	1.9	1.5	1.7	1.6	1.5	0.5	-0.5	1.2
Pavlov. Cond. lever contacts	0.6	0.7	1.7	-0.6	-1.2	-0.6	1.3	0.9	1.1	1.0	1.0	-0.4	0.4	0.2
Pavlov. Cond. magazine entry number	0.8	1.0	2.1	1.1	1.2	1.2	-1.0	-0.9	-1.0	-0.7	-0.7	-0.9	0.9	-1.5
Pavlov. Cond. intertrial magazine entries	2.8	3.4	6.3	2.1	2.2	2.0	-2.5	-1.7	-2.0	-2.0	-1.9	-1.0	1.0	-1.1
Pavlov. Cond. lever-magazine prob. diff.	1.8	2.2	3.9	-1.3	-1.8	-1.6	2.0	1.4	1.7	1.5	1.5	0.8	-0.8	1.6
Pavlov. Cond. response bias	0.9	1.1	2.2	-0.7	-1.2	-1.2	1.1	1.0	1.1	0.9	0.9	0.8	-0.8	1.5
Pavlov. Cond. lever latency	1.1	1.5	2.4	-0.8	-1.4	-1.4	1.4	1.5	1.4	1.4	1.5	0.6	-0.6	0.7
Pavlov. Cond. magazine entry latency	2.0	2.3	4.2	1.6	1.8	1.2	-1.8	-2.0	-1.7	-1.6	-1.7	-0.9	0.9	-1.1
Pavlov. Cond. change in total contacts	0.2	0.3	1.1	-0.6	-0.0	-0.3	-0.2	-0.2	-0.0	-0.1	-0.2	1.1	-1.1	1.0
Pavlov. Cond. index score	1.8	2.4	4.7	1.4	1.8	1.5	-1.7	-2.2	-1.8	-1.7	-1.8	-0.7	0.7	-0.9
Pavlov. Cond. latency score	1.7	2.2	4.2	1.4	1.7	1.4	-1.7	-2.0	-1.7	-1.6	-1.7	-0.7	0.7	-0.9
Pavlov. Cond. lever contacts	1.7	2.4	3.2	1.0	1.7	1.7	-1.7	-1.8	-1.7	-1.7	-1.8	-1.1	1.1	-1.3
Pavlov. Cond. magazine entry number	0.7	0.8	1.9	-1.1	-1.1	-0.7	1.0	1.4	1.0	0.9	1.0	0.1	-0.1	0.5
Pavlov. Cond. intertrial magazine entries	0.2	0.2	1.0	-0.2	-0.0	0.4	0.0	0.2	0.1	0.1	0.0	-0.8	0.8	-1.0
Pavlov. Cond. lever-magazine prob. diff.	1.2	1.5	3.5	1.2	1.5	1.1	-1.4	-1.9	-1.4	-1.3	-1.4	-0.3	0.3	-0.5
Pavlov. Cond. response bias	1.1	1.4	2.4	0.9	1.4	1.3	-1.4	-1.6	-1.4	-1.4	-1.5	-0.6	0.6	-0.7
Time in closed arm before self-admin	0.1	0.1	0.4	0.7	0.1	-0.1	-0.0	0.1	-0.0	0.1	0.1	-0.5	0.5	0.1
Time in closed arm after self-admin	0.4	0.4	1.0	-0.5	-0.6	-0.4	0.4	0.7	0.5	0.3	0.7	0.6	-0.6	1.0
Time in open arm before self-admin	1.9	2.1	4.0	-1.3	-1.2	-1.1	1.6	0.8	1.1	1.3	1.2	2.0	-2.0	1.8
Time in open arm after self-admin	0.5	0.6	1.6	0.8	0.8	0.5	-0.6	-1.0	-0.9	-0.5	-1.2	-0.5	0.5	-0.7
Bone: periosteal estimation	2.9	6.0	14.7	-3.8	-2.9	-2.5	2.6	2.8	2.7	2.5	2.5	0.9	-0.9	0.4
Bone: periosteal perimeter	2.7	4.4	11.5	-3.4	-2.3	-2.4	2.1	2.1	2.1	1.9	1.9	1.5	-1.5	1.0
Bone: post-yield work	2.1	2.9	5.5	-2.4	-2.0	-1.7	2.0	2.0	1.9	1.9	1.7	0.8	-0.8	0.2
Progressive ratio test 1 active lever presses	2.3	2.4	5.1	1.8	1.7	2.3	-1.6	-1.6	-1.8	-1.9	-1.8	-0.2	0.2	-0.5
Progressive ratio test 1 breakpoint	2.1	2.2	4.5	1.7	1.6	2.1	-1.6	-1.5	-1.7	-1.8	-1.7	-0.2	0.2	-0.4
Progressive ratio test 1 inactive lever presses	1.7	1.9	4.7	0.5	1.4	1.2	-1.6	-1.6	-1.6	-2.2	-1.9	0.5	-0.5	0.3
Progressive ratio test 2 active lever presses	0.4	0.5	1.8	-0.6	-0.0	0.3	0.3	-0.2	-0.1	0.1	-0.4	1.4	-1.4	0.9
Progressive ratio test 2 breakpoint	0.5	0.6	2.2	-0.8	-0.1	0.1	0.4	-0.1	-0.0	0.2	-0.3	1.5	-1.5	1.0
Progressive ratio test 2 inactive lever presses	0.5	0.5	2.0	-0.6	0.2	0.3	-0.1	-0.5	-0.4	-0.5	-0.6	1.4	-1.4	0.5
Incentive Sensitization - Responses	1.7	1.8	3.9	-2.0	-1.3	-1.3	1.5	1.1	1.2	1.5	0.6	1.5	-1.5	0.8
Incentive Sensitization - Breakpoint	2.2	2.3	4.4	-2.1	-1.5	-1.4	1.7	1.3	1.4	1.7	0.8	1.7	-1.7	1.0
Sum of active levers in priming session hrs 5-6	0.4	0.4	1.2	-0.2	0.1	0.1	0.4	-0.4	-0.2	0.2	-0.4	1.1	-1.1	1.1
Progressive ratio	0.2	0.3	0.6	-0.2	-0.3	-0.3	0.7	0.1	0.4	0.7	0.8	0.7	-0.7	0.5
Food seeking constrained by brief footshock	0.4	0.5	1.4	-0.2	0.7	1.2	-0.5	-1.2	-0.7	-0.5	-0.7	-0.5	0.5	-0.1
Seeking ratio, punishment vs. effort	0.3	0.4	0.9	-0.2	0.5	0.7	-0.7	-0.6	-0.6	-0.7	-1.0	-0.5	0.5	-0.1
Retroperitoneal fat weight	0.9	3.0	4.1	1.6	1.9	1.8	-2.0	-1.7	-1.9	-2.0	-1.9	-1.2	1.2	-1.5
Reaction time number correct	0.5	0.8	1.5	-0.5	-1.1	-0.8	0.9	1.0	1.1	1.0	1.2	0.6	-0.6	0.2
Reaction time mean minus median	0.5	0.6	1.3	0.6	0.9	0.2	-1.1	-0.8	-0.8	-1.0	-0.8	0.6	-0.6	0.6
Reaction time mean minus median AUC	0.6	0.8	1.9	0.8	0.7	0.1	-0.6	-0.9	-0.6	-0.6	-0.6	1.3	-1.3	1.4
Reaction time num false alarms	3.5	4.8	6.3	1.7	2.2	2.2	-2.0	-2.5	-2.3	-2.2	-2.3	-2.2	2.2	-2.2
Reaction time num false alarms AUC	3.3	4.6	6.6	1.7	2.3	2.1	-2.1	-2.6	-2.4	-2.5	-2.5	-1.6	1.6	-1.6
Reaction time trials correct on left	0.5	0.8	1.5	-0.5	-1.1	-0.8	0.9	1.0	1.1	1.0	1.2	0.6	-0.6	0.2
Reaction time trials on left	0.4	0.6	1.2	-0.4	-0.9	-0.7	0.7	0.9	1.0	0.9	1.1	0.5	-0.5	0.1
Reaction time mean	0.1	0.1	0.3	-0.3	0.2	-0.2	-0.4	-0.1	-0.2	-0.5	-0.3	0.5	-0.5	0.0
Reaction time mean AUC	0.1	0.2	0.7	-0.4	-0.2	-0.5	-0.1	0.2	0.2	-0.1	0.1	0.8	-0.8	0.3
Median of all reaction times	0.1	0.1	0.4	-0.6	-0.2	-0.4	-0.1	0.3	0.2	-0.1	0.1	0.3	-0.3	-0.2
Reaction time omissions	2.2	2.9	6.3	1.2	1.9	1.1	-2.5	-1.9	-1.9	-2.1	-1.9	-1.1	1.1	-1.3
Reaction time false alarm rate	3.0	4.2	6.7	1.5	2.3	2.1	-2.0	-2.5	-2.4	-2.4	-2.6	-1.5	1.5	-1.3
Reaction time premature initiation rate	0.6	0.8	1.7	0.2	0.9	1.1	-1.1	-0.8	-1.0	-1.3	-1.2	-0.7	0.7	-0.5
Reaction time premature initiations	0.1	0.1	0.5	-0.3	0.2	0.4	-0.5	-0.1	-0.3	-0.7	-0.4	-0.3	0.3	-0.3
Std. dev. reaction times	0.4	0.5	1.0	0.4	0.8	0.1	-1.0	-0.8	-0.7	-1.0	-0.7	0.7	-0.7	0.6
Reaction time trials completed	0.4	0.6	1.2	-0.4	-0.9	-0.7	0.7	0.9	1.0	0.9	1.1	0.5	-0.5	0.1
Reaction time trials AUC	0.6	0.8	1.5	-0.7	-1.1	-0.9	0.9	1.0	1.2	1.0	1.2	0.5	-0.5	0.2
Run reversals in cocaine runway, females	0.3	0.3	1.0	-1.0	-0.5	-0.9	0.4	0.2	0.5	0.3	0.2	0.3	-0.3	0.7
Run reversals in cocaine runway, males	0.1	0.1	0.4	0.7	0.2	-0.5	-0.3	-0.1	-0.2	-0.2	-0.3	0.4	-0.4	0.5
Latency to leave start box in cocaine runway	0.1	0.1	0.5	-0.1	0.0	0.0	-0.0	-0.0	-0.0	-0.2	-0.3	0.0	-0.0	0.7
Latency to leave start box in cocaine runway, F	0.6	0.7	1.1	0.9	0.9	0.8	-0.9	-0.9	-1.0	-1.1	-1.0	-0.5	0.5	-0.1
Latency to leave start box in cocaine runway, M	1.5	1.4	2.7	-1.7	-1.2	-1.1	1.1	1.2	1.2	1.1	0.9	1.0	-1.0	1.6
Std. dev. time between licks in bursts	0.9	1.1	3.0	1.7	0.6	1.3	-0.1	-0.3	-0.5	-0.1	-0.4	-1.6	1.6	-1.1
Total sessions with >9 infusions	0.9	1.0	2.0	-0.6	-0.9	-0.2	1.0	0.8	0.8	1.0	0.8	1.4	-1.4	1.4
Short access day 1 total inactive lever presses	0.8	0.9	4.1	-0.6	0.0	-0.2	0.1	-0.5	-0.2	-0.4	0.1	1.6	-1.6	2.0
Short access day 10 total inactive lever presses	0.9	1.0	3.5	-1.9	-1.1	-1.3	0.5	0.8	0.9	0.2	0.6	0.8	-0.8	1.1
Short access day 1 total infusions	0.2	0.2	0.5	-0.3	0.2	0.2	-0.4	-0.4	-0.4	-0.5	-0.7	0.2	-0.2	0.7
Short access day 10 total infusions	1.0	1.2	2.6	0.9	1.2	1.6	-1.1	-1.2	-1.3	-1.3	-1.3	0.2	-0.2	-0.1
Short access total infusions	0.1	0.1	0.6	0.1	0.2	0.8	-0.4	-0.2	-0.3	-0.5	-0.5	0.3	-0.3	0.2
Short access day 1 locomotion	0.3	0.4	0.7	0.6	0.7	0.5	-0.7	-0.8	-0.8	-0.8	-0.6	0.1	-0.1	-0.2
Short access day 10 total locomotion	0.7	0.8	1.9	0.6	1.0	0.8	-1.2	-1.0	-1.1	-1.4	-0.9	-0.5	0.5	-0.5
Short access total locomotion	0.8	0.8	1.5	1.2	1.0	1.1	-0.9	-1.0	-1.0	-1.0	-0.8	-0.2	0.2	-0.5
One hour access (0.3 mA shock)	3.7	4.3	6.2	-2.1	-2.0	-1.7	2.2	1.8	1.9	2.1	2.0	2.5	-2.5	1.7
Compulsive drug intake	1.6	1.6	3.5	-1.9	-1.5	-1.0	1.4	1.2	1.4	1.6	1.4	0.5	-0.5	0.6
One hour access (shock baseline)	2.5	2.8	6.8	-1.0	-1.3	-1.4	1.6	1.2	1.2	1.3	1.1	2.6	-2.6	2.2
Social response proportion	1.3	1.4	3.7	0.2	1.4	0.6	-1.8	-1.6	-1.4	-1.9	-1.2	-0.1	0.1	-0.0
Social responses	2.1	2.6	3.8	1.7	1.8	1.3	-2.0	-1.8	-1.7	-1.8	-1.6	-1.3	1.3	-1.2
Social time	1.1	1.5	2.8	0.3	1.2	0.3	-1.7	-1.2	-1.2	-1.5	-1.4	-1.5	1.5	-0.8
Soleus weight	0.8	2.4	3.5	-1.4	-1.5	-1.9	1.5	1.2	1.4	1.5	1.4	1.7	-1.7	1.8
Bone: stiffness	3.9	6.2	10.2	-3.2	-2.9	-2.8	2.6	2.8	2.8	2.6	2.6	1.5	-1.5	0.7
Tibialis anterior weight	4.8	16.5	21.3	-3.5	-4.0	-4.6	4.1	3.4	4.0	4.2	4.0	4.2	-4.2	4.4
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.2	0.4	0.2	-0.2	0.0	-0.2	-0.2	-0.0	-0.0	0.4	-0.4	0.5
Time to tail flick, vehicle, after self-admin	0.5	0.6	1.4	-0.8	-0.9	-1.2	0.6	0.7	1.0	0.7	1.0	0.0	-0.0	-0.3
Time to tail flick, test, before self-admin	1.9	1.8	3.5	1.3	1.6	0.7	-1.5	-1.9	-1.6	-1.8	-1.9	-0.3	0.3	-0.3
Time to tail flick, test, after self-admin	1.2	1.3	2.8	-1.7	-1.3	-1.7	0.8	1.1	1.2	0.7	0.6	0.7	-0.7	1.3
Delta time to tail flick, vehicle, before/after SA	0.8	0.8	1.4	-1.2	-1.1	-0.8	0.8	1.0	1.2	1.0	1.1	-0.1	0.1	-0.8
Delta time to tail flick, test, before/after SA	2.8	2.5	5.2	-2.3	-1.9	-1.7	1.3	2.0	1.9	1.5	1.7	0.4	-0.4	1.0
Tibia length	0.5	1.5	4.6	-2.1	-1.5	-1.3	1.3	1.3	1.3	1.2	1.1	0.5	-0.5	0.3
Ambulatory time before self-admin	0.2	0.2	0.8	0.2	-0.0	0.1	0.3	0.0	-0.0	0.1	0.1	0.9	-0.9	0.8
Ambulatory time after self-admin	0.5	0.6	2.5	-1.6	-0.6	-0.2	0.3	0.2	0.2	-0.0	0.0	1.1	-1.1	1.1
Bone: tissue strength	2.0	2.0	2.2	-1.1	-1.5	-1.5	1.4	1.4	1.5	1.3	1.4	1.4	-1.4	1.4
Total heroin consumption	2.3	2.7	5.4	-2.3	-1.9	-1.4	2.0	1.5	1.9	2.1	1.7	1.0	-1.0	0.4
Bone: trabecular number	0.2	0.3	0.8	-0.7	-0.6	-0.6	0.3	0.9	0.6	0.6	0.6	-0.2	0.2	-0.5
Bone: trabecular spacing	0.1	0.2	0.6	-0.2	-0.0	0.3	0.1	-0.1	-0.0	-0.0	0.0	0.8	-0.8	0.7
Bone: trabecular thickness	0.1	0.1	0.6	-0.2	0.2	0.0	-0.4	0.3	-0.2	-0.3	-0.4	-0.5	0.5	-0.8
Bone: trabecular tissue density	0.1	0.1	0.4	0.1	0.3	0.4	0.0	-0.6	-0.5	-0.0	-0.3	-0.1	0.1	-0.2
Water consumed over 24 hours	0.2	0.3	0.5	-0.2	-0.6	-0.1	0.7	0.4	0.7	0.7	0.7	-0.4	0.4	-0.5
Number of responses in last shaping day	2.3	2.4	4.5	1.5	1.9	1.0	-1.7	-2.1	-2.0	-2.1	-1.8	-0.2	0.2	-0.7