Hub : Genes

Zmiz2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr14_85473816_85474419 0.38 0.35 4.8e-05 0.04 0.05 0.07 0.05 9.8e-06 5.4e-06 8.1e-08 3.7e-06
2 Brain gene expression Zmiz2 0.2 0.09 2.4e-13 0.15 0.14 0.14 0.14 1.4e-13 6.5e-13 7.8e-13 2.7e-13
3 NAcc gene expression Zmiz2 0.08 0.06 4.2e-08 0.05 0.04 0.04 0.04 2.7e-08 2.1e-06 4.9e-07 6.9e-07
4 IC isoform ratio XM_017599125.3 0.11 0.08 7.4e-04 0.08 0.05 0.06 0.06 3.3e-04 4.9e-03 1.2e-03 1.4e-03
5 Liver gene expression Zmiz2 0.09 0.05 3.8e-09 0.04 0.08 0.06 0.07 2.4e-05 9.2e-09 1.2e-07 7.3e-08
6 PL gene expression Zmiz2 0.07 0.04 1.6e-04 0.04 0.03 0.03 0.04 2.5e-05 1.5e-04 3.9e-04 5.2e-05
7 Brain isoform ratio XM_017599125.3 0.04 0.03 7.0e-04 0.04 0.03 0.03 0.03 2.9e-04 8.3e-04 1.4e-03 1.3e-03
8 IC intron excision ratio chr14_85474496_85474714 0.08 0.06 8.7e-04 0.08 0.07 0.03 0.07 3.2e-04 4.9e-04 2.8e-02 6.0e-04
9 PL intron excision ratio chr14_85474496_85474714 0.06 0.06 5.2e-05 0.06 0.04 0.04 0.05 8.7e-07 5.2e-05 1.1e-05 1.6e-06
10 pVTA intron excision ratio chr14_85474496_85474714 0.04 0.03 1.2e-05 0.05 0.07 0.06 0.06 8.8e-05 1.7e-06 1.5e-05 1.1e-05
11 pVTA gene expression Zmiz2 0.09 0.05 2.2e-07 0.11 0.1 0.11 0.11 4.9e-09 1.8e-08 7.7e-09 5.2e-09
12 NAcc intron excision ratio chr14_85473816_85474419 0.02 0.02 7.3e-04 0.01 0.01 0.01 0.01 2.1e-03 4.3e-03 9.1e-03 4.9e-03
13 NAcc intron excision ratio chr14_85474496_85474714 0.02 0.01 9.5e-04 0.02 0.01 0.01 0.01 9.6e-04 2.6e-03 5.7e-03 2.2e-03
14 Liver intron excision ratio chr14_85473816_85474419 0.06 0.05 1.9e-05 0.03 0.02 0.02 0.03 1.4e-04 1.5e-03 4.3e-03 2.7e-04
15 Liver intron excision ratio chr14_85474496_85474714 0.05 0.04 8.8e-05 0.02 0.01 0.01 0.02 1.2e-03 7.8e-03 2.5e-02 3.8e-03
16 pVTA intron excision ratio chr14_85473816_85474419 0.03 0.02 7.4e-04 0.03 0.04 0.03 0.03 2.6e-03 2.3e-04 1.0e-03 2.5e-03
17 Brain intron excision ratio chr14_85472049_85472389 0.1 0.06 2.4e-04 0.01 0.02 0.03 0.03 1.9e-02 3.4e-03 1.0e-03 1.9e-03
18 LHb gene expression Zmiz2 0.2 0.13 3.3e-03 0.03 0.09 0.04 0.04 7.0e-02 4.6e-03 3.6e-02 4.4e-02
19 Brain intron excision ratio chr14_85465773_85471286 0.2 0.1 4.4e-09 0.09 0.1 0.1 0.1 1.1e-08 7.3e-10 3.3e-09 2.5e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.00.10.2-0.40.40.4-0.30.20.3-0.30.00.20.1-0.1-0.20.20.1-0.1-0.1-0.3-0.10.2
Area under the delay curve4.14.87.42.4-1.8-1.91.9-2.1-1.62.0-2.7-2.5-2.6-2.02.1-2.12.5-2.52.7-0.3-2.71.8
BMI with tail0.20.61.2-0.1-1.1-1.10.8-1.0-1.00.7-0.8-0.9-0.8-1.10.5-0.50.4-0.40.70.6-0.4-0.4
BMI without tail0.41.33.11.2-1.5-1.51.3-1.1-1.31.3-1.4-1.1-1.0-1.81.1-1.11.1-1.11.00.5-0.4-0.0
Body weight1.67.211.22.2-2.8-2.82.7-3.0-2.83.0-3.4-3.2-3.0-2.92.7-2.72.7-2.72.90.9-2.20.6
Weight adjusted by age0.30.41.00.2-0.2-0.30.4-0.7-0.60.4-0.5-0.7-0.9-0.80.7-0.70.5-0.50.9-0.1-1.00.6
Bone surface0.00.10.20.0-0.1-0.10.3-0.4-0.40.3-0.4-0.3-0.3-0.10.3-0.30.4-0.40.20.4-0.0-0.2
Bone volume0.10.10.30.1-0.3-0.30.4-0.5-0.50.3-0.5-0.4-0.4-0.30.3-0.30.5-0.50.30.4-0.2-0.1
Breakpoint value in progressive ratio session0.20.31.1-0.2-0.4-0.30.5-0.7-0.50.2-0.3-0.5-0.8-1.10.4-0.40.5-0.50.70.3-0.60.1
Number of licking bursts2.23.67.72.8-1.6-1.61.7-2.1-1.61.7-2.0-2.4-2.3-1.61.8-1.82.2-2.22.21.0-1.90.7
Context. condit. distance diff. score2.22.64.2-1.61.91.9-1.81.61.8-1.81.61.51.62.1-1.91.9-1.71.7-1.6-0.50.9-0.2
Locomotion velocity, session 10.50.61.8-0.90.30.4-0.40.70.3-0.71.01.41.00.6-0.70.7-0.60.6-1.00.21.2-0.7
Locomotion distance, session 10.70.94.2-0.71.21.2-1.20.70.9-0.30.10.7-0.1-0.60.4-0.40.2-0.20.5-2.1-1.22.0
Locomotion velocity, session 20.91.13.9-0.8-0.0-0.0-0.00.6-0.2-0.61.31.31.31.1-0.80.8-0.80.8-1.41.02.0-1.7
Locomotion distance, session 20.81.12.3-1.41.21.2-1.21.41.1-1.01.21.51.20.6-0.60.6-0.90.9-1.0-1.10.70.3
Locomotion velocity, session 31.11.22.2-1.01.41.4-1.51.41.4-1.01.21.31.11.0-0.20.2-1.01.0-0.9-1.40.30.5
Locomotion distance, session 30.50.51.20.8-1.0-1.00.9-0.7-0.81.1-0.3-0.4-0.6-0.61.1-1.10.5-0.50.50.4-0.1-0.3
Stereotopy head waving bouts, day 30.50.61.8-0.40.90.9-0.81.10.7-0.60.81.31.10.3-0.20.2-0.60.6-0.9-0.80.80.0
Stereotopy head waving duration, day 32.32.75.1-1.81.81.8-1.71.91.6-1.81.82.31.91.3-1.51.5-1.61.6-1.8-0.91.3-0.2
Locomotion velocity, session 70.10.20.40.6-0.6-0.60.6-0.4-0.50.4-0.3-0.1-0.2-0.20.1-0.10.3-0.30.10.60.2-0.3
Locomotion distance, session 70.10.10.6-0.10.10.1-0.10.10.4-0.40.3-0.00.10.4-0.80.8-0.20.2-0.20.40.1-0.1
Stereotopy head waving bouts, day 70.10.10.50.00.40.4-0.40.30.3-0.40.50.30.20.70.2-0.2-0.20.2-0.2-0.5-0.00.1
Stereotopy head waving duration, day 70.10.10.7-0.10.40.4-0.40.30.3-0.20.20.50.10.40.5-0.5-0.00.0-0.0-0.8-0.20.4
Locomotion velocity, session 81.31.54.2-1.21.31.3-1.11.21.1-1.21.51.51.32.1-1.11.1-1.01.0-1.4-0.11.1-0.6
Locomotion distance, session 85.27.69.8-3.03.13.1-3.03.13.0-2.93.03.13.02.8-2.72.7-2.82.8-2.8-1.41.9-0.2
Degree of sensitization distance2.62.76.1-1.61.81.7-1.61.61.7-2.21.41.31.61.9-2.52.5-1.51.5-1.6-0.10.9-0.2
Degree of sensitization stereotypy0.10.10.30.10.0-0.0-0.0-0.2-0.1-0.0-0.1-0.1-0.30.30.6-0.60.2-0.20.2-0.3-0.40.2
Conditioned locomotion0.60.73.6-0.51.11.1-1.00.61.0-0.2-0.20.1-0.2-0.40.4-0.40.4-0.40.5-1.7-1.31.9
Cocaine response after cond. corrected1.41.72.61.5-1.2-1.31.2-1.5-1.21.3-1.3-1.3-1.6-1.11.4-1.41.6-1.61.50.2-1.30.5
Cocaine response after cond. not corrected2.02.33.61.6-1.4-1.41.3-1.7-1.31.5-1.5-1.6-1.9-1.51.6-1.61.8-1.81.80.1-1.70.8
Cocaine response before conditioning0.10.10.4-0.30.50.5-0.50.40.6-0.40.10.10.1-0.1-0.10.1-0.30.30.0-0.6-0.40.6
Saline control response0.20.30.6-0.70.30.2-0.30.50.3-0.50.70.70.60.8-0.10.1-0.50.5-0.7-0.00.7-0.5
Bone: connectivity density0.20.30.6-0.40.70.8-0.60.50.5-0.60.40.60.50.2-0.60.6-0.50.5-0.5-0.20.4-0.1
Bone: cortical apparent density0.40.52.01.4-0.9-0.90.9-0.7-0.80.7-0.4-0.6-0.5-0.30.8-0.80.5-0.50.40.5-0.0-0.3
Bone: cortical area1.82.84.41.3-1.6-1.61.5-1.8-1.72.0-2.0-1.9-1.9-1.82.1-2.11.6-1.61.90.1-1.50.6
Bone: cortical porosity0.10.10.5-0.7-0.00.00.00.0-0.1-0.4-0.00.30.1-0.4-0.70.70.0-0.0-0.10.30.2-0.2
Bone: cortical porosity0.20.20.9-1.00.50.5-0.50.30.4-0.7-0.10.20.1-0.2-0.70.7-0.10.1-0.0-0.3-0.30.4
Bone: cortical thickness1.42.33.61.5-1.4-1.41.3-1.6-1.41.7-1.8-1.7-1.8-1.91.7-1.71.5-1.51.8-0.1-1.50.8
Bone: cortical thickness0.70.83.50.71.01.0-1.00.41.0-0.7-0.8-1.0-0.4-0.5-0.20.20.5-0.50.6-1.6-1.51.9
Bone: cortical tissue density0.40.51.91.4-1.0-0.91.0-0.8-0.90.8-0.4-0.6-0.5-0.30.8-0.80.5-0.50.40.60.0-0.4
Condit. Reinf. active minus inactive responses1.01.12.80.4-1.7-1.71.5-1.1-1.50.9-0.9-0.3-0.6-0.30.9-0.90.8-0.80.41.60.4-1.1
Condit. Reinf. active-inactive response ratio1.01.14.4-1.4-0.6-0.60.5-0.1-0.5-0.50.70.90.61.1-0.80.8-0.90.9-1.02.01.6-2.1
Condit. Reinf. active responses0.60.81.60.8-1.3-1.21.1-0.8-1.10.7-1.0-0.6-0.5-0.31.0-1.01.1-1.10.50.90.1-0.4
Condit. Reinf. inactive responses1.01.22.51.5-0.6-0.50.6-0.7-0.50.9-1.0-1.2-1.1-0.91.4-1.41.6-1.61.2-0.5-1.31.2
Incentive salience index mean1.72.13.21.1-1.8-1.81.7-1.5-1.71.5-1.8-1.1-1.3-1.01.7-1.71.7-1.71.21.1-0.5-0.2
Condit. Reinf. lever presses1.52.14.71.3-0.9-0.80.8-1.0-0.81.4-1.8-1.2-1.4-1.42.2-2.21.9-1.91.6-0.7-1.51.4
Condit. Reinf. active minus inactive responses0.20.20.6-0.70.50.5-0.50.60.7-0.60.20.40.40.8-0.40.4-0.30.3-0.3-0.50.00.3
Condit. Reinf. active-inactive response ratio0.20.20.50.0-0.3-0.30.2-0.3-0.10.3-0.4-0.6-0.5-0.00.5-0.50.6-0.60.6-0.3-0.70.5
Condit. Reinf. active responses0.40.61.2-1.10.70.7-0.71.00.8-0.80.50.90.90.8-0.70.7-0.80.8-0.8-0.50.60.0
Condit. Reinf. inactive responses1.21.52.3-1.31.11.1-1.01.41.0-1.31.01.51.51.1-1.31.3-1.51.5-1.5-0.21.3-0.6
Condit. Reinf. lever presses0.20.20.8-0.20.70.7-0.60.50.7-0.6-0.20.20.30.9-0.30.3-0.00.0-0.2-0.6-0.20.5
Condit. Reinf. lever reinforcers received0.20.30.6-0.70.60.6-0.60.70.7-0.60.20.60.70.6-0.50.5-0.50.5-0.6-0.50.30.2
Conditioned reinforcement - actives0.10.21.71.3-0.4-0.20.20.1-0.30.0-0.5-0.10.3-0.30.3-0.30.1-0.1-0.20.00.6-0.3
Conditioned reinforcement - inactives0.30.51.91.4-0.9-0.70.6-0.5-0.50.4-1.0-0.8-0.4-0.80.5-0.50.8-0.80.40.2-0.10.0
Conditioned locomotion0.91.26.12.5-1.1-1.11.2-0.6-1.31.0-1.2-0.6-0.2-1.11.4-1.40.9-0.90.30.30.6-0.5
Patch foraging indifference point 0 sec1.73.16.61.1-2.5-2.52.3-2.6-2.21.7-1.3-1.6-2.1-0.70.8-0.81.4-1.41.52.6-0.8-1.3
Patch foraging indifference point AUC0.10.20.90.2-0.4-0.40.6-0.1-0.4-0.0-0.2-0.10.20.1-0.10.10.3-0.3-0.31.00.7-0.6
Delay disc. indifference point, 0s delay2.22.47.61.7-1.0-0.80.9-1.7-0.81.1-1.8-2.4-2.4-0.90.9-0.91.1-1.12.3-0.1-2.81.5
Delay disc. indifference point, 16s delay1.51.72.51.6-1.3-1.51.5-1.3-1.31.6-1.5-1.3-1.2-1.51.3-1.31.5-1.51.20.4-0.70.3
Delay disc. indifference point, 2s delay3.84.211.11.9-1.3-1.21.2-1.9-1.11.0-2.6-2.5-2.8-1.81.8-1.82.1-2.12.9-0.8-3.32.4
Delay disc. indifference point, 24s delay1.41.52.91.2-1.2-1.31.1-1.3-1.01.7-1.4-1.1-1.5-1.31.0-1.01.4-1.41.50.4-1.30.7
Delay disc. indifference point, 4s delay4.95.18.82.2-1.7-1.71.8-2.1-1.71.5-2.8-2.7-2.8-2.02.3-2.32.7-2.72.9-0.6-3.02.1
Delay disc. indifference point, 8s delay1.51.83.01.4-0.8-1.00.9-0.9-0.81.6-1.6-1.3-1.4-1.11.5-1.51.7-1.71.6-0.8-1.61.6
Indifference point function ln k0.10.20.90.40.00.0-0.2-0.10.10.3-0.5-0.5-0.5-0.60.4-0.40.4-0.40.6-0.6-0.90.9
Indifference point function log k0.10.20.90.40.00.0-0.2-0.10.10.3-0.5-0.5-0.5-0.60.4-0.40.4-0.40.6-0.6-0.90.9
Patch foraging total patch changes 0 sec1.73.37.91.0-2.6-2.62.4-2.6-2.31.7-1.4-1.6-2.0-0.60.8-0.81.4-1.41.42.8-0.6-1.5
Patch foraging total patch changes 12 sec1.11.55.90.4-1.7-1.71.8-1.7-1.70.9-0.7-0.9-1.1-0.20.1-0.10.6-0.60.62.40.1-1.6
Patch foraging total patch changes 18 sec1.52.35.80.7-2.2-2.22.2-2.1-2.01.4-1.2-1.5-1.40.20.6-0.61.0-1.00.92.4-0.0-1.7
Patch foraging total patch changes 24 sec0.61.13.3-0.90.10.1-0.10.30.3-0.91.00.70.81.8-1.51.5-1.01.0-1.21.21.2-1.6
Patch foraging total patch changes 6 sec1.82.87.11.0-2.4-2.42.3-2.2-2.41.5-1.3-1.3-1.5-1.00.8-0.81.2-1.21.12.7-0.1-1.6
Patch foraging time to switch 0 sec0.20.41.3-0.60.80.9-0.90.70.9-0.60.60.50.40.6-0.40.4-0.60.6-0.3-1.2-0.20.5
Patch foraging water rate 0 sec1.02.15.00.3-2.1-2.12.1-1.8-2.11.6-1.2-0.6-1.1-0.91.1-1.11.1-1.10.72.20.4-1.6
Patch foraging water rate 12 sec0.10.20.50.2-0.5-0.50.5-0.4-0.50.5-0.7-0.1-0.2-0.10.5-0.50.5-0.50.2-0.10.0-0.2
Patch foraging water rate 18 sec0.50.83.10.40.30.3-0.3-0.00.30.4-0.6-0.2-0.7-1.40.9-0.90.5-0.51.0-1.7-1.51.8
Patch foraging water rate 24 sec0.10.20.7-0.2-0.4-0.40.30.2-0.30.4-0.20.40.5-0.50.5-0.50.0-0.0-0.4-0.20.8-0.6
Patch foraging water rate 6 sec0.40.61.30.7-0.4-0.50.6-0.2-0.40.9-1.0-0.2-0.3-1.11.1-1.11.2-1.20.5-0.4-0.20.6
Seeking ratio, delayed vs. immediate footshock0.20.31.10.30.50.4-0.10.80.2-0.0-0.00.50.6-0.80.7-0.70.2-0.2-0.3-1.10.40.7
Distance traveled before self-admin0.10.10.3-0.5-0.1-0.10.2-0.3-0.20.5-0.20.0-0.10.30.1-0.10.1-0.10.00.50.1-0.3
Distance traveled after self-admin0.10.20.50.1-0.00.10.2-0.2-0.10.4-0.5-0.3-0.4-0.40.4-0.40.3-0.30.5-0.6-0.70.7
Extensor digitorum longus weight2.28.815.62.3-3.9-4.03.9-3.4-3.63.5-3.0-2.7-2.8-3.02.7-2.73.0-3.02.62.1-1.0-0.8
Bone: elastic displacement0.70.81.5-1.20.90.9-0.90.80.8-0.91.20.90.90.5-0.80.8-1.21.2-0.8-0.30.6-0.3
Bone: elastic work0.20.20.8-0.20.00.00.0-0.4-0.20.4-0.2-0.3-0.7-0.90.4-0.40.2-0.20.7-0.4-0.90.6
Bone: endosteal estimation0.00.10.4-0.20.00.0-0.1-0.3-0.10.3-0.6-0.4-0.40.20.3-0.30.4-0.40.40.0-0.50.3
Bone: endosteal perimeter0.81.73.01.2-0.9-0.90.8-1.1-0.81.5-1.7-1.7-1.4-0.91.6-1.61.5-1.51.5-0.4-1.41.0
Epididymis fat weight0.41.42.30.8-1.3-1.31.3-1.5-1.41.4-1.4-1.5-1.5-1.31.3-1.30.9-0.91.30.5-0.9-0.0
Delta time in closed arm before/after self-admin7.67.011.5-2.23.33.4-3.23.43.1-2.73.12.72.62.1-2.12.1-2.72.7-2.2-3.10.71.4
Delta time in open arm before/after self-admin4.94.98.12.1-2.5-2.62.8-2.8-2.82.8-2.0-2.0-2.1-1.61.9-1.92.0-2.01.62.8-0.2-1.6
Diff in mean of infusions in LGA sessions0.20.20.8-0.40.30.4-0.40.00.2-0.30.6-0.2-0.4-0.30.3-0.3-0.30.30.5-0.9-0.90.9
Delay discount exponential model param4.24.77.4-2.31.81.9-1.92.11.6-2.02.72.52.61.9-2.02.0-2.62.6-2.70.32.7-1.9
Extinction: sum of active levers before priming0.10.10.60.0-0.4-0.50.30.0-0.20.30.10.30.3-0.20.2-0.20.1-0.1-0.30.40.8-0.7
Active lever presses in extinction session 60.40.42.1-0.40.50.5-0.60.30.6-0.50.50.0-0.2-0.4-0.00.0-0.30.30.4-1.5-1.11.3
Bone: final force0.20.30.9-0.6-0.7-0.70.7-0.6-1.00.5-0.5-0.1-0.2-0.20.3-0.30.3-0.30.10.80.4-0.7
Bone: final moment0.20.41.2-0.5-0.9-0.90.9-0.8-1.10.6-0.6-0.3-0.4-0.40.4-0.40.5-0.50.30.80.2-0.7
Food consumed during 24 hour testing period0.91.33.10.6-1.8-1.81.7-1.2-1.81.0-0.7-0.3-0.5-0.30.6-0.60.8-0.80.21.70.8-1.5
Glucose7.912.541.41.4-5.5-5.45.4-3.4-5.42.8-1.2-0.7-0.8-0.40.8-0.81.6-1.6-0.26.43.6-5.8
Heart weight0.50.83.6-1.1-0.9-0.90.8-0.7-0.90.20.20.4-0.00.6-0.20.2-0.40.4-0.41.91.0-1.9
Delay discount hyperbolic model param4.65.18.2-2.31.81.9-1.92.11.6-2.02.82.62.72.1-2.22.2-2.72.7-2.80.52.9-2.0
Intermittent access intake day 1-15 change0.51.13.61.5-1.1-1.21.2-1.0-1.20.8-0.9-0.8-0.4-0.60.7-0.71.1-1.10.21.90.8-1.4
Intermittent access intake escalation0.51.13.61.5-1.1-1.11.2-1.0-1.20.8-0.9-0.8-0.4-0.60.7-0.71.1-1.10.21.90.7-1.2
Intermittent access intake escalation 20.40.42.80.9-0.5-0.50.6-0.5-0.60.5-0.2-0.30.0-0.20.1-0.10.5-0.5-0.21.70.8-1.1
Intermitt. access day 1 inactive lever presses0.00.21.20.30.10.4-0.50.70.5-0.2-0.20.00.40.1-0.20.2-0.10.1-0.2-1.1-0.10.7
Intermitt. access day 15 inactive lever presses1.12.34.91.7-2.2-1.91.8-1.5-1.71.6-1.8-1.3-0.8-1.31.2-1.21.6-1.60.61.80.6-1.3
Intermitt. access escalation Index0.30.43.0-0.5-0.2-0.30.5-0.6-0.50.00.0-0.2-0.00.1-0.20.2-0.00.0-0.31.70.8-1.5
Intermittent access day 1 total infusions0.20.42.20.80.10.3-0.20.20.20.0-0.5-0.4-0.4-0.70.3-0.30.3-0.30.6-1.2-1.11.5
Intermittent access day 15 total infusions1.01.44.62.2-1.2-1.11.2-1.2-1.31.0-1.3-1.3-0.9-1.31.1-1.11.3-1.30.81.2-0.2-0.4
Intermittent access terminal intake (last 3 days)0.50.72.61.6-0.8-0.60.8-0.8-0.90.6-0.8-0.7-0.4-0.70.5-0.50.8-0.80.21.50.4-0.8
Intermittent access total infusions0.50.62.71.6-0.6-0.50.7-0.6-0.70.7-0.9-0.8-0.6-1.10.7-0.70.8-0.80.60.5-0.30.1
Intermittent access day 1 locomotion0.50.74.4-0.50.70.8-0.71.30.7-0.40.31.10.9-0.40.1-0.1-0.40.4-0.4-2.10.01.2
Intermittent access day 15 total locomotion0.40.72.31.5-0.8-0.70.9-0.6-0.91.1-0.8-0.6-0.5-1.31.2-1.20.7-0.70.6-0.0-0.1-0.0
Intermittent access total locomotion0.60.72.51.6-0.7-0.60.8-0.5-0.81.1-0.9-0.4-0.5-1.41.1-1.10.8-0.80.7-0.3-0.30.4
Intermittent access standard deviation0.91.94.6-0.51.21.3-1.21.71.1-1.21.21.62.11.0-1.31.3-1.31.3-2.00.22.1-1.0
Left kidney weight0.10.71.8-0.1-0.0-0.0-0.0-0.4-0.10.9-0.9-0.3-0.9-1.21.0-1.00.5-0.51.1-1.2-1.31.3
Right kidney weight0.20.72.7-0.50.10.2-0.2-0.40.10.7-0.7-0.4-1.0-1.30.8-0.80.2-0.21.2-1.3-1.61.5
Cocaine induced anxiety1.62.23.61.3-1.7-1.71.9-1.8-1.91.8-1.3-1.1-1.3-1.61.5-1.51.5-1.51.11.6-0.1-1.0
Post-drug Anxiety2.22.44.01.5-1.7-1.71.7-2.0-1.71.7-1.4-1.9-1.8-1.71.5-1.51.4-1.41.61.2-1.1-0.2
Baseline Anxiety0.20.31.40.10.30.3-0.40.00.5-0.30.1-0.6-0.5-0.1-0.00.0-0.20.20.6-0.9-1.21.1
Tail length2.28.512.83.2-3.2-3.13.1-3.0-3.13.6-3.0-2.6-2.9-3.33.2-3.23.2-3.22.91.0-1.70.5
Length with tail2.19.213.42.9-3.1-3.13.2-3.3-3.33.7-3.5-3.0-3.2-3.03.3-3.33.4-3.43.21.1-2.20.6
Length without tail0.51.63.30.2-1.1-1.11.2-1.7-1.31.5-1.6-1.5-1.8-1.01.2-1.21.1-1.11.70.5-1.50.4
Times rat made contact with spout2.73.19.6-1.8-0.3-0.30.30.4-0.2-1.21.81.81.61.9-2.12.1-1.51.5-2.12.42.8-3.1
Lifetime Intake0.40.52.41.6-0.6-0.50.6-0.5-0.70.6-0.8-0.6-0.4-1.00.7-0.70.7-0.70.40.3-0.20.1
Liver weight, left0.50.81.5-1.01.11.2-1.21.11.2-0.70.31.10.7-0.2-0.80.8-0.70.7-0.4-1.1-0.10.9
Liver weight, right1.01.73.4-1.81.51.5-1.71.81.8-1.11.01.41.30.3-0.70.7-1.21.2-0.9-1.80.21.0
Locomotor activity0.40.63.50.6-1.0-1.01.0-0.8-1.00.4-0.2-0.3-0.20.1-0.10.10.2-0.2-0.11.90.7-1.5
Locomotor testing distance0.61.13.92.0-0.7-0.70.6-0.9-0.80.8-1.3-1.5-1.0-0.80.9-0.91.2-1.21.00.5-0.90.5
Locomotor testing rearing1.22.34.32.1-1.9-1.91.9-1.8-2.01.6-1.3-1.6-1.2-0.81.2-1.21.4-1.40.92.1-0.0-1.0
Locomotion in novel chamber2.53.26.6-1.92.62.5-2.31.42.2-2.01.70.90.51.9-1.91.9-1.91.9-0.4-1.7-1.21.5
Locomotion in novel chamber post-restriction1.52.44.4-1.42.02.0-2.02.02.1-1.71.31.31.51.5-1.41.4-1.41.4-1.2-1.80.30.9
Fecal boli incidents, locomotor time 10.20.31.4-0.90.30.3-0.20.50.4-0.50.71.20.6-0.2-0.10.1-0.30.3-0.5-0.40.5-0.1
Change in fecal boli incidents, locomotor task0.40.41.60.7-0.6-0.60.5-0.2-0.60.9-0.1-0.20.30.9-0.30.30.1-0.1-0.51.31.0-1.3
Time >=10cm from walls, locomotor time 10.20.30.7-0.40.70.7-0.80.30.6-0.00.60.30.20.4-0.50.5-0.80.8-0.2-0.2-0.20.1
Bouts of movement, locomotor time 10.60.72.41.5-0.7-0.60.6-1.0-0.80.5-1.2-1.3-0.80.4-0.40.40.5-0.50.51.3-0.3-0.6
Total resting periods, locomotor time 10.30.31.21.1-0.4-0.30.2-0.5-0.40.0-0.7-0.8-0.30.5-0.60.60.0-0.00.01.00.1-0.6
Rest time, locomotor task time 10.10.20.80.90.10.1-0.00.40.2-0.4-0.1-0.40.50.1-0.50.5-0.10.1-0.50.10.7-0.3
Distance moved, locomotor task time 10.20.30.9-0.3-0.6-0.60.6-0.5-0.60.8-0.20.0-0.4-0.71.0-1.00.5-0.50.40.1-0.1-0.0
Vertical activity count, locomotor time 10.00.10.2-0.4-0.3-0.30.2-0.4-0.30.5-0.10.2-0.3-0.30.4-0.40.1-0.10.30.3-0.1-0.1
Time >=10cm from walls, locomotor time 20.40.63.20.51.31.2-1.21.11.0-0.10.20.20.60.10.0-0.0-0.30.3-0.3-1.8-0.31.2
Bouts of movement, locomotor time 21.52.45.11.8-0.7-0.60.5-0.8-0.81.4-2.0-1.6-1.5-1.51.5-1.51.9-1.91.8-1.6-2.12.3
Total resting periods, locomotor time 21.32.34.01.8-0.9-0.80.7-0.9-0.91.6-2.0-1.7-1.5-1.31.5-1.52.0-2.01.8-1.1-1.91.9
Rest time, locomotor task time 20.30.41.2-0.80.00.1-0.20.30.1-0.30.50.20.70.6-0.70.7-0.80.8-0.80.81.1-1.1
Distance moved, locomotor task time 20.10.10.40.10.60.6-0.40.50.6-0.10.20.30.20.2-0.10.1-0.10.1-0.1-0.6-0.20.6
Vertical activity count, locomotor time 20.30.41.0-0.10.90.9-0.90.50.9-0.50.30.30.00.0-0.30.3-0.50.50.1-0.9-0.81.0
Light reinforcement 10.30.72.81.7-0.6-0.60.7-0.5-0.50.7-0.9-0.9-0.6-0.60.9-0.91.0-1.00.7-0.6-0.60.5
Light reinforcement 21.11.66.21.50.20.2-0.2-0.10.30.6-1.3-1.1-1.0-1.41.3-1.31.2-1.21.4-1.8-2.02.5
Bone: marrow area0.00.10.3-0.20.20.2-0.2-0.20.00.2-0.6-0.4-0.40.30.3-0.30.4-0.40.4-0.1-0.50.4
Bone: maximum diameter2.54.67.11.4-2.6-2.72.6-2.6-2.62.7-2.4-2.0-2.2-1.72.5-2.51.9-1.92.01.3-1.1-0.4
Bone: maximum force0.10.30.6-0.1-0.4-0.40.4-0.6-0.70.6-0.8-0.6-0.5-0.40.6-0.60.6-0.60.50.2-0.3-0.0
Bone: maximum moment0.20.40.7-0.0-0.6-0.60.6-0.8-0.80.7-0.8-0.7-0.7-0.60.8-0.80.7-0.70.70.2-0.40.0
Mean time between licks in bursts0.10.30.70.7-0.8-0.80.8-0.6-0.80.7-0.3-0.5-0.2-0.10.5-0.50.5-0.50.00.10.4-0.8
Mean num. licks in bursts3.96.112.2-3.51.11.1-1.22.01.2-2.22.73.02.82.6-2.82.8-2.72.7-3.00.73.3-2.5
Cd content in liver0.50.61.50.5-1.2-1.11.2-0.8-1.20.7-0.2-0.3-0.2-0.40.6-0.60.3-0.30.11.20.6-1.2
Co content in liver1.01.21.91.0-1.2-1.21.4-1.4-1.31.3-1.1-1.2-1.2-0.51.2-1.21.0-1.01.11.0-0.7-0.2
Cu content in liver0.20.21.0-0.5-0.6-0.60.7-0.3-0.70.20.10.40.10.00.1-0.1-0.00.0-0.30.70.8-1.0
Fe content in liver1.01.22.5-0.71.61.5-1.51.31.6-1.21.11.10.90.9-0.90.9-0.80.8-0.7-1.1-0.00.8
K content in liver2.32.25.01.8-0.6-0.70.7-1.1-0.81.8-1.6-1.4-1.5-2.21.9-1.91.5-1.51.7-1.1-1.61.5
Mg content in liver0.40.40.90.4-0.5-0.50.5-0.8-0.50.8-0.7-0.9-0.9-0.70.9-0.90.3-0.30.9-0.1-0.80.4
Mn content in liver0.40.41.40.6-0.4-0.40.4-0.3-0.30.8-0.4-0.2-0.4-0.91.2-1.20.8-0.80.6-0.3-0.50.6
Na content in liver2.32.55.12.2-1.4-1.41.4-1.8-1.51.7-1.9-2.1-1.8-1.41.4-1.41.7-1.71.70.4-1.30.5
Rb content in liver0.80.91.90.3-1.4-1.31.3-1.0-1.31.4-0.6-0.4-0.7-1.01.2-1.20.5-0.50.60.70.1-0.7
Se content in liver1.41.63.61.6-1.1-1.21.2-1.2-1.11.5-1.1-1.2-1.3-1.91.5-1.51.4-1.41.40.1-1.00.6
Sr content in liver3.73.26.51.2-1.8-1.92.0-2.5-2.01.9-1.7-1.9-2.5-1.61.5-1.51.7-1.72.30.8-1.90.3
Zn content in liver0.60.72.40.2-0.4-0.30.4-0.5-0.51.1-0.4-0.3-0.7-1.51.5-1.50.7-0.70.8-0.8-0.60.7
Bone: minimum diameter0.10.10.4-0.60.30.3-0.40.30.30.3-0.00.20.2-0.00.3-0.3-0.30.3-0.1-0.60.00.2
Time in familiar zone, hab. session 10.10.10.20.40.20.2-0.00.10.20.0-0.3-0.30.00.30.4-0.40.2-0.20.0-0.3-0.10.3
Time in novel zone, hab. session 10.20.20.7-0.4-0.6-0.60.4-0.3-0.40.10.50.20.0-0.3-0.30.3-0.30.3-0.20.70.5-0.8
Total zone transitions, hab. session 10.00.00.3-0.40.10.1-0.00.20.00.10.40.50.20.00.2-0.20.0-0.0-0.1-0.40.20.1
Total locomotion distance, hab. session 10.60.92.41.0-0.1-0.10.1-0.3-0.00.8-0.9-0.7-0.9-0.71.3-1.30.9-0.91.1-1.1-1.41.6
Locomotion velocity, hab. session 10.30.51.90.60.10.1-0.2-0.10.20.4-0.7-0.3-0.6-0.40.8-0.80.6-0.60.8-1.1-1.21.4
Time in familiar zone, hab. session 21.31.32.1-1.41.11.1-1.21.21.2-1.21.21.21.21.3-1.21.2-1.41.4-1.1-0.50.7-0.1
Time in novel zone, hab. session 21.21.22.61.0-1.4-1.41.6-1.3-1.61.1-0.8-0.8-0.8-1.20.8-0.81.1-1.10.61.30.1-0.9
Total zone transitions, hab. session 20.70.91.70.9-0.7-0.70.8-0.7-0.81.2-0.8-0.5-0.8-1.31.2-1.21.3-1.31.0-0.5-0.70.7
Total locomotion distance, hab. session 21.01.32.01.3-1.0-1.01.1-1.0-1.11.4-1.2-0.9-1.1-1.21.4-1.41.4-1.41.3-0.1-0.90.8
Locomotion velocity, hab. session 21.62.13.41.7-1.1-1.11.2-1.2-1.21.7-1.6-1.3-1.5-1.51.8-1.81.7-1.71.6-0.4-1.41.2
Novel to familiar place preference ratio0.10.10.40.5-0.5-0.50.5-0.2-0.50.20.1-0.00.10.1-0.00.00.2-0.2-0.20.50.6-0.6
Novelty place preference0.20.20.70.4-0.5-0.50.5-0.1-0.50.10.30.10.30.1-0.20.20.0-0.0-0.40.60.8-0.8
Time in novel zone, NPP test0.20.21.00.2-0.5-0.50.5-0.1-0.50.10.50.20.30.1-0.30.3-0.10.1-0.50.80.9-1.0
Total zone transitions, NPP test0.40.52.5-0.70.80.8-0.80.40.8-0.00.20.1-0.2-0.50.3-0.30.1-0.10.5-1.6-1.11.5
Total locomotion distance, NPP test0.70.93.90.90.40.4-0.4-0.00.40.5-0.8-0.8-0.8-1.20.9-0.90.7-0.71.1-1.6-1.62.0
Locomotion velocity, NPP test0.81.24.11.10.20.2-0.2-0.20.20.7-1.0-1.0-0.9-1.31.1-1.11.0-1.01.3-1.5-1.72.0
Intraocular pressure0.40.61.71.3-0.7-0.60.8-0.7-0.90.9-0.2-0.7-0.5-0.31.1-1.10.7-0.70.50.8-0.1-0.3
Delta distance traveled before/after self-admin0.40.52.00.00.80.8-0.80.70.8-0.70.50.10.2-0.1-0.50.5-0.40.4-0.0-1.4-0.61.2
Delta ambulatory time before/after self-admin0.40.51.9-0.40.80.8-0.80.70.9-0.90.60.20.2-0.1-0.60.6-0.50.50.0-1.4-0.71.2
Parametrial fat weight1.02.35.40.5-2.2-2.32.3-1.6-2.21.6-1.6-0.5-0.7-1.30.9-0.91.1-1.10.42.31.1-1.8
Pavlov. Cond. lever latency0.10.20.80.1-0.4-0.50.4-0.4-0.50.20.1-0.3-0.10.2-0.30.3-0.20.2-0.10.90.3-0.8
Pavlov. Cond. magazine entry latency1.01.32.5-1.31.41.5-1.61.41.5-1.50.71.31.21.1-0.90.9-0.90.9-1.1-1.00.50.3
Pavlov. Cond. change in total contacts1.31.42.40.9-1.4-1.41.4-1.2-1.51.3-1.2-0.8-1.0-1.11.6-1.61.5-1.50.90.7-0.3-0.2
Pavlov. Cond. index score0.70.81.8-0.91.31.3-1.31.21.3-1.10.51.00.80.5-0.40.4-0.50.5-0.6-1.20.10.7
Pavlov. Cond. latency score0.60.71.6-0.81.21.2-1.21.11.2-0.90.51.00.80.4-0.40.4-0.40.4-0.6-1.30.10.8
Pavlov. Cond. lever contacts0.20.21.0-0.30.60.7-0.70.70.7-0.40.10.50.40.00.2-0.20.1-0.1-0.2-1.0-0.10.8
Pavlov. Cond. magazine entry number1.01.32.11.4-1.2-1.21.3-1.4-1.21.3-0.8-1.4-1.4-1.21.0-1.01.0-1.01.30.5-1.00.2
Pavlov. Cond. intertrial magazine entries1.82.25.41.6-0.2-0.20.2-0.7-0.20.8-2.0-1.7-1.5-1.51.5-1.52.0-2.01.8-1.2-2.22.3
Pavlov. Cond. lever-magazine prob. diff.0.81.02.2-1.01.41.4-1.51.31.4-1.20.61.21.00.6-0.50.5-0.60.6-0.7-1.40.10.8
Pavlov. Cond. response bias0.20.30.7-0.60.60.6-0.80.70.7-0.50.00.70.50.30.1-0.1-0.10.1-0.3-0.90.10.5
Pavlov. Cond. lever latency3.24.37.82.1-1.8-1.81.8-2.1-1.82.5-1.7-2.1-2.4-2.82.5-2.52.0-2.02.5-0.1-2.01.1
Pavlov. Cond. magazine entry latency0.10.10.50.40.40.4-0.30.20.3-0.3-0.3-0.20.10.7-0.30.30.1-0.1-0.1-0.1-0.10.2
Pavlov. Cond. change in total contacts0.20.30.6-0.70.60.5-0.50.60.6-0.80.20.60.70.8-0.70.7-0.40.4-0.6-0.20.5-0.1
Pavlov. Cond. index score1.01.33.0-1.01.21.1-1.21.21.1-1.40.61.01.21.7-1.51.5-1.01.0-1.3-0.20.9-0.3
Pavlov. Cond. latency score1.01.32.7-1.01.31.3-1.31.31.2-1.50.61.01.21.6-1.41.4-1.01.0-1.2-0.40.7-0.1
Pavlov. Cond. lever contacts3.34.58.4-2.02.02.0-2.02.32.0-2.61.82.22.52.9-2.52.5-2.02.0-2.5-0.22.0-0.9
Pavlov. Cond. magazine entry number0.50.71.80.5-0.2-0.20.2-0.4-0.10.7-0.4-0.5-0.8-1.31.2-1.20.8-0.81.0-0.9-1.21.2
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.1-0.5-0.50.4-0.3-0.30.50.1-0.1-0.3-0.50.4-0.40.1-0.10.30.1-0.1-0.0
Pavlov. Cond. lever-magazine prob. diff.1.21.63.2-1.11.31.3-1.31.31.2-1.50.71.11.31.8-1.61.6-1.21.2-1.3-0.20.9-0.3
Pavlov. Cond. response bias2.02.75.8-1.51.41.4-1.41.61.3-2.01.31.71.92.4-2.12.1-1.51.5-2.00.31.7-1.0
Time in closed arm before self-admin0.20.31.00.3-0.6-0.70.5-0.4-0.50.4-0.7-0.4-0.4-1.00.4-0.40.7-0.70.40.0-0.20.2
Time in closed arm after self-admin1.41.53.3-0.51.51.4-1.61.71.5-1.41.21.01.20.6-1.01.0-1.01.0-0.9-1.80.11.2
Time in open arm before self-admin0.60.72.0-0.31.11.2-1.10.91.1-1.40.40.20.40.7-0.80.8-0.40.4-0.3-1.1-0.51.1
Time in open arm after self-admin0.40.41.20.4-0.6-0.60.9-0.6-0.80.7-0.6-0.1-0.1-0.10.5-0.50.5-0.5-0.11.10.8-1.1
Bone: periosteal estimation0.51.02.00.4-0.7-0.80.7-1.1-0.91.3-1.4-1.2-1.2-0.81.3-1.31.1-1.11.20.0-1.10.5
Bone: periosteal perimeter1.72.94.61.5-1.3-1.31.2-1.6-1.32.1-2.0-2.0-2.0-1.62.1-2.11.7-1.72.0-0.4-1.91.1
Bone: post-yield work0.10.20.60.2-0.1-0.10.1-0.3-0.10.1-0.7-0.7-0.5-0.00.4-0.40.5-0.50.5-0.3-0.60.5
Progressive ratio test 1 active lever presses0.40.52.51.6-0.4-0.30.4-0.1-0.40.7-0.9-0.5-0.3-1.20.7-0.70.8-0.80.5-0.4-0.40.8
Progressive ratio test 1 breakpoint0.50.62.61.6-0.5-0.40.4-0.1-0.50.8-1.0-0.6-0.3-1.20.8-0.80.8-0.80.5-0.4-0.40.8
Progressive ratio test 1 inactive lever presses3.04.47.42.7-2.3-2.22.1-1.5-2.12.3-2.7-1.8-1.5-2.72.6-2.62.4-2.41.7-0.2-0.80.7
Progressive ratio test 2 active lever presses0.60.73.71.9-0.6-0.40.6-0.8-0.60.7-1.1-1.2-0.8-0.90.5-0.50.7-0.70.80.4-0.70.3
Progressive ratio test 2 breakpoint0.50.63.11.8-0.6-0.40.6-0.8-0.50.6-1.0-1.1-0.8-0.80.4-0.40.7-0.70.80.5-0.70.2
Progressive ratio test 2 inactive lever presses0.91.54.52.1-1.3-1.01.1-0.8-1.11.3-1.8-1.4-0.8-1.61.3-1.31.3-1.30.9-0.1-0.50.4
Incentive Sensitization - Responses0.40.61.80.9-0.7-0.50.6-1.2-0.60.3-1.0-1.4-1.2-0.30.4-0.40.5-0.51.00.7-1.00.0
Incentive Sensitization - Breakpoint0.40.51.80.8-0.6-0.40.6-1.1-0.50.2-0.9-1.3-1.2-0.10.3-0.30.4-0.40.90.8-0.9-0.0
Sum of active levers in priming session hrs 5-60.60.61.50.4-0.6-0.60.7-0.9-0.50.6-0.5-0.8-1.1-1.20.8-0.80.6-0.61.1-0.2-1.10.6
Progressive ratio0.20.30.8-0.60.60.6-0.50.70.80.10.50.70.5-0.3-0.10.1-0.50.5-0.3-0.90.10.5
Food seeking constrained by brief footshock3.03.65.52.3-1.3-1.31.3-1.4-1.52.2-2.2-2.2-1.9-2.32.4-2.41.9-1.92.2-0.9-2.01.7
Seeking ratio, punishment vs. effort1.62.44.62.2-1.4-1.41.3-1.4-1.61.2-2.0-1.8-1.6-1.21.6-1.61.9-1.91.6-0.1-1.40.9
Retroperitoneal fat weight0.41.83.31.2-1.8-1.81.8-1.6-1.81.5-1.6-1.3-1.1-1.01.2-1.21.1-1.11.01.3-0.1-0.8
Reaction time number correct0.10.10.9-0.2-0.3-0.30.3-0.1-0.30.10.40.30.20.4-0.30.3-0.10.1-0.40.40.7-0.9
Reaction time mean minus median1.23.04.9-2.01.41.4-1.41.31.4-1.92.11.51.52.2-2.12.1-2.22.2-1.70.11.3-1.1
Reaction time mean minus median AUC0.82.13.6-1.51.41.5-1.31.11.2-1.81.51.11.21.9-1.91.9-1.71.7-1.4-0.00.9-0.7
Reaction time num false alarms1.31.85.22.3-1.3-1.31.1-1.3-1.11.4-1.3-1.8-1.5-1.41.2-1.21.3-1.31.50.2-1.40.7
Reaction time num false alarms AUC1.32.04.42.1-1.1-1.10.9-1.4-0.91.3-1.4-1.9-1.8-1.61.3-1.31.2-1.21.9-0.2-2.01.3
Reaction time trials correct on left0.10.10.9-0.2-0.3-0.30.3-0.1-0.30.10.40.30.20.4-0.30.3-0.10.1-0.40.40.7-0.9
Reaction time trials on left0.10.20.9-0.2-0.3-0.30.2-0.1-0.30.10.50.30.30.5-0.30.3-0.20.2-0.40.40.7-0.9
Reaction time mean0.71.12.5-0.91.31.4-1.21.01.2-1.11.50.60.80.7-0.90.9-1.61.6-0.8-0.30.30.0
Reaction time mean AUC0.91.53.0-1.01.61.6-1.61.21.5-1.41.60.70.90.9-1.01.0-1.71.7-0.9-0.70.20.3
Median of all reaction times0.50.71.6-0.51.21.2-1.10.91.0-0.81.20.40.60.2-0.40.4-1.31.3-0.5-0.40.10.3
Reaction time omissions0.81.12.1-0.81.21.2-1.20.91.1-1.21.40.70.81.0-1.31.3-1.41.4-0.8-0.00.4-0.2
Reaction time false alarm rate1.62.25.02.2-0.9-0.90.7-1.3-0.71.2-1.5-1.9-1.9-1.71.3-1.31.3-1.32.0-0.4-2.21.7
Reaction time premature initiation rate1.82.54.5-2.02.02.0-1.92.12.0-1.81.21.61.71.0-1.31.3-1.21.2-1.4-1.50.50.8
Reaction time premature initiations0.91.63.6-1.91.41.4-1.31.61.4-1.41.21.41.51.0-1.21.2-1.01.0-1.3-0.80.80.1
Std. dev. reaction times1.01.94.0-1.51.31.3-1.41.01.3-1.61.81.01.11.6-1.71.7-2.02.0-1.2-0.00.7-0.5
Reaction time trials completed0.10.20.9-0.2-0.3-0.30.2-0.1-0.30.10.50.30.30.5-0.30.3-0.20.2-0.40.40.7-0.9
Reaction time trials AUC0.10.10.7-0.2-0.3-0.40.3-0.2-0.40.20.30.20.10.3-0.20.2-0.10.1-0.30.30.6-0.8
Run reversals in cocaine runway, females0.60.62.80.70.90.9-0.70.20.7-0.2-0.5-0.9-0.50.5-0.20.2-0.00.00.6-1.3-1.51.7
Run reversals in cocaine runway, males0.20.20.80.9-0.4-0.50.5-0.1-0.50.3-0.3-0.10.2-0.10.3-0.30.3-0.3-0.20.20.6-0.5
Latency to leave start box in cocaine runway0.60.61.40.7-0.5-0.60.6-1.0-0.70.6-0.8-1.0-1.2-0.70.9-0.90.6-0.61.10.3-1.10.6
Latency to leave start box in cocaine runway, F1.92.24.51.8-1.0-1.01.1-1.8-1.11.5-1.6-2.1-2.1-1.31.3-1.31.2-1.22.00.4-2.11.0
Latency to leave start box in cocaine runway, M0.50.41.6-1.30.50.3-0.30.70.3-1.00.81.10.90.4-0.20.2-0.50.5-0.8-0.10.9-0.4
Std. dev. time between licks in bursts0.10.20.70.8-0.3-0.30.3-0.2-0.20.2-0.8-0.8-0.10.10.1-0.10.7-0.70.1-0.4-0.10.0
Total sessions with >9 infusions1.01.32.6-0.71.21.2-1.31.61.2-1.40.81.41.50.9-0.90.9-1.01.0-1.2-1.00.80.3
Short access day 1 total inactive lever presses1.62.13.71.5-1.5-1.51.7-1.3-1.81.9-1.6-1.0-0.9-1.91.8-1.81.6-1.60.90.70.0-0.3
Short access day 10 total inactive lever presses0.10.20.80.9-0.3-0.20.40.3-0.30.6-0.30.10.5-0.60.5-0.50.4-0.4-0.3-0.10.8-0.1
Short access day 1 total infusions0.91.12.6-1.01.11.2-1.11.61.0-0.91.01.51.50.7-0.60.6-1.01.0-1.2-1.40.90.3
Short access day 10 total infusions0.30.31.00.30.50.7-0.80.80.7-0.9-0.00.30.50.3-0.50.5-0.30.3-0.3-1.0-0.20.9
Short access total infusions0.10.10.30.20.20.4-0.30.60.2-0.30.10.50.5-0.1-0.10.1-0.10.1-0.4-0.40.40.1
Short access day 1 locomotion1.01.24.8-0.81.21.2-1.21.61.1-1.11.01.41.00.5-0.40.4-0.90.9-0.6-2.2-0.01.3
Short access day 10 total locomotion1.12.06.9-0.91.61.5-1.52.31.5-0.71.12.01.80.5-0.60.6-1.11.1-1.2-2.60.61.4
Short access total locomotion1.72.04.7-1.01.51.6-1.52.21.5-1.21.22.11.90.9-0.90.9-1.21.2-1.5-1.81.10.6
One hour access (0.3 mA shock)0.70.84.22.1-0.9-0.50.6-0.5-0.71.0-1.0-0.8-0.5-1.40.9-0.90.7-0.70.6-0.1-0.30.4
Compulsive drug intake1.11.32.9-1.41.11.3-1.41.01.4-1.41.20.80.61.7-1.31.3-1.31.3-0.6-0.8-0.30.6
One hour access (shock baseline)0.40.72.51.6-0.7-0.60.8-0.6-0.81.1-0.9-0.7-0.4-1.50.9-0.90.8-0.80.50.2-0.0-0.0
Social response proportion0.60.72.40.5-1.0-1.01.0-0.8-1.11.1-0.9-0.3-0.6-1.60.7-0.70.9-0.90.60.30.0-0.2
Social responses1.51.94.01.7-1.9-1.92.0-1.5-1.91.7-1.1-1.0-0.9-1.31.0-1.01.3-1.30.71.30.4-1.2
Social time0.20.21.00.2-0.6-0.60.8-0.5-0.70.60.30.2-0.0-0.30.1-0.1-0.10.1-0.10.50.7-1.0
Soleus weight1.13.25.61.8-1.3-1.21.3-1.6-1.12.1-2.0-2.0-2.0-2.42.3-2.31.6-1.62.1-0.8-2.01.4
Bone: stiffness0.10.10.3-0.50.20.3-0.30.50.2-0.3-0.10.10.50.6-0.10.1-0.20.2-0.5-0.10.5-0.1
Tibialis anterior weight0.93.15.31.1-2.2-2.22.3-2.3-2.21.8-1.9-1.9-2.0-1.31.5-1.51.6-1.61.71.5-1.0-0.4
Time to tail flick, vehicle, before self-admin0.30.31.90.20.0-0.1-0.10.30.10.3-0.10.1-0.0-0.80.7-0.70.2-0.20.3-1.4-0.41.1
Time to tail flick, vehicle, after self-admin0.20.20.70.70.50.3-0.20.00.00.70.2-0.4-0.3-0.60.2-0.2-0.20.20.4-0.7-0.70.8
Time to tail flick, test, before self-admin0.40.41.0-1.00.30.3-0.20.30.4-0.70.80.70.50.5-0.80.8-0.50.5-0.70.80.7-0.8
Time to tail flick, test, after self-admin2.72.85.61.8-1.6-1.71.5-1.3-1.71.7-1.8-1.2-1.4-2.42.1-2.12.0-2.01.6-0.2-1.00.9
Delta time to tail flick, vehicle, before/after SA0.20.20.50.00.70.7-0.60.10.4-0.00.2-0.3-0.20.2-0.40.4-0.30.30.2-0.4-0.70.6
Delta time to tail flick, test, before/after SA1.61.73.41.9-1.2-1.31.1-1.0-1.41.6-1.6-1.1-1.0-1.51.7-1.71.4-1.41.1-0.2-0.60.5
Tibia length0.41.14.10.50.90.9-0.90.10.70.3-1.1-0.7-0.7-1.10.9-0.90.8-0.81.0-1.6-1.72.0
Ambulatory time before self-admin0.20.41.00.5-0.5-0.50.6-0.7-0.61.0-0.8-0.7-0.7-0.20.7-0.70.6-0.60.60.6-0.4-0.1
Ambulatory time after self-admin0.10.10.8-0.20.20.3-0.10.10.20.1-0.3-0.0-0.2-0.40.2-0.20.1-0.10.4-0.8-0.60.9
Bone: tissue strength0.80.82.7-1.1-0.2-0.20.20.2-0.2-0.50.80.70.81.3-0.80.8-0.90.9-1.01.31.4-1.6
Total heroin consumption0.20.22.5-1.60.10.2-0.20.20.2-0.30.50.70.3-0.4-0.30.3-0.30.3-0.3-0.10.3-0.3
Bone: trabecular number0.00.00.1-0.20.20.3-0.20.10.1-0.20.10.20.1-0.3-0.10.1-0.10.1-0.1-0.10.00.0
Bone: trabecular spacing0.81.12.21.5-1.2-1.21.0-1.1-0.91.0-1.2-1.4-1.1-0.80.9-0.91.2-1.21.10.4-0.80.2
Bone: trabecular thickness0.50.61.8-0.51.31.3-1.10.81.1-0.70.10.40.20.2-0.30.3-0.20.2-0.0-1.3-0.71.3
Bone: trabecular tissue density0.71.12.8-1.50.70.7-0.70.80.6-1.21.31.21.01.7-1.31.3-1.01.0-1.00.20.9-0.7
Water consumed over 24 hours0.60.83.80.7-1.3-1.31.3-0.8-1.20.4-0.3-0.1-0.10.1-0.20.20.5-0.5-0.22.01.0-1.6
Number of responses in last shaping day0.10.11.1-0.50.10.2-0.20.50.1-0.1-0.20.30.30.10.2-0.20.0-0.0-0.1-1.1-0.00.6