Hub : Genes

Zmiz2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr14_85473816_85474419 0.38 0.35 4.8e-05 0.04 0.05 0.07 0.05 9.8e-06 5.4e-06 8.1e-08 3.6e-06
2 Brain gene expression Zmiz2 0.2 0.09 2.4e-13 0.15 0.14 0.14 0.14 1.4e-13 6.5e-13 7.6e-13 2.6e-13
3 NAcc gene expression Zmiz2 0.08 0.06 4.2e-08 0.05 0.04 0.04 0.04 2.7e-08 2.1e-06 4.9e-07 6.5e-07
4 IC isoform ratio XM_017599125.3 0.11 0.08 7.4e-04 0.08 0.05 0.06 0.06 3.3e-04 4.9e-03 1.2e-03 1.4e-03
5 Liver gene expression Zmiz2 0.09 0.05 3.8e-09 0.04 0.08 0.06 0.07 2.4e-05 9.2e-09 1.2e-07 6.7e-08
6 PL gene expression Zmiz2 0.07 0.04 1.6e-04 0.04 0.03 0.03 0.04 2.5e-05 1.5e-04 3.9e-04 5.4e-05
7 Brain isoform ratio XM_017599125.3 0.04 0.03 7.0e-04 0.04 0.03 0.03 0.03 2.9e-04 8.3e-04 1.4e-03 1.3e-03
8 IC intron excision ratio chr14_85474496_85474714 0.08 0.06 8.7e-04 0.08 0.07 0.03 0.07 3.2e-04 4.9e-04 2.9e-02 6.2e-04
9 PL intron excision ratio chr14_85474496_85474714 0.06 0.06 5.2e-05 0.06 0.04 0.04 0.05 8.7e-07 5.2e-05 9.4e-06 1.6e-06
10 pVTA intron excision ratio chr14_85474496_85474714 0.04 0.03 1.2e-05 0.05 0.07 0.06 0.06 8.8e-05 1.7e-06 1.5e-05 1.1e-05
11 pVTA gene expression Zmiz2 0.09 0.05 2.2e-07 0.11 0.1 0.11 0.11 4.9e-09 1.8e-08 7.7e-09 5.3e-09
12 NAcc intron excision ratio chr14_85473816_85474419 0.02 0.02 7.3e-04 0.01 0.01 0.01 0.01 2.1e-03 4.3e-03 9.1e-03 4.3e-03
13 NAcc intron excision ratio chr14_85474496_85474714 0.02 0.01 9.5e-04 0.02 0.01 0.01 0.01 9.6e-04 2.6e-03 5.7e-03 2.3e-03
14 Liver intron excision ratio chr14_85473816_85474419 0.06 0.05 1.9e-05 0.03 0.02 0.02 0.03 1.4e-04 1.5e-03 4.3e-03 2.4e-04
15 Liver intron excision ratio chr14_85474496_85474714 0.05 0.04 8.8e-05 0.02 0.01 0.01 0.02 1.2e-03 7.8e-03 2.6e-02 3.5e-03
16 pVTA intron excision ratio chr14_85473816_85474419 0.03 0.02 7.4e-04 0.03 0.04 0.03 0.03 2.6e-03 2.3e-04 1.0e-03 2.5e-03
17 Brain intron excision ratio chr14_85472049_85472485 0.05 0.04 8.0e-03 0 0.01 0.01 0.01 2.7e-01 6.5e-02 2.5e-02 8.0e-02
18 Brain intron excision ratio chr14_85472049_85472389 0.1 0.06 2.4e-04 0.01 0.02 0.03 0.03 1.9e-02 3.4e-03 1.0e-03 1.8e-03
19 LHb gene expression Zmiz2 0.2 0.13 3.3e-03 0.03 0.09 0.04 0.04 7.0e-02 4.6e-03 3.6e-02 4.2e-02
20 Brain intron excision ratio chr14_85465773_85471286 0.2 0.1 4.4e-09 0.09 0.1 0.1 0.1 1.1e-08 7.3e-10 3.3e-09 2.4e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.00.10.20.4-0.4-0.40.30.2-0.30.3-0.0-0.20.10.10.2-0.2-0.10.1-0.1-0.40.3-0.10.2
Area under the delay curve3.04.67.4-2.41.81.9-1.9-2.11.6-2.02.72.5-2.62.0-2.12.1-2.52.52.70.40.4-2.71.8
BMI with tail0.20.61.20.11.11.1-0.8-1.01.0-0.70.80.9-0.81.1-0.50.5-0.40.40.70.8-0.6-0.4-0.4
BMI without tail0.21.33.1-1.21.51.5-1.3-1.11.3-1.31.41.1-1.01.8-1.11.1-1.11.11.00.7-0.5-0.4-0.0
Body weight1.66.911.2-2.22.82.8-2.7-3.02.8-3.03.43.2-3.02.9-2.72.7-2.72.72.91.6-0.9-2.20.6
Weight adjusted by age0.10.41.0-0.20.20.3-0.4-0.70.6-0.40.50.7-0.90.8-0.70.7-0.50.50.90.10.1-1.00.6
Bone surface0.00.10.2-0.00.10.1-0.3-0.40.4-0.30.40.3-0.30.1-0.30.3-0.40.40.20.3-0.4-0.0-0.2
Bone volume0.10.10.3-0.10.30.3-0.4-0.50.5-0.30.50.4-0.40.3-0.30.3-0.50.50.30.3-0.4-0.2-0.1
Breakpoint value in progressive ratio session0.10.31.10.20.40.3-0.5-0.70.5-0.20.30.5-0.81.1-0.40.4-0.50.50.70.4-0.3-0.60.1
Number of licking bursts1.23.57.7-2.81.61.6-1.7-2.11.6-1.72.02.4-2.31.6-1.81.8-2.22.22.21.2-1.0-1.90.7
Context. condit. distance diff. score2.12.54.21.6-1.9-1.91.81.6-1.81.8-1.6-1.51.6-2.11.9-1.91.7-1.7-1.6-1.00.50.9-0.2
Locomotion velocity, session 10.50.61.80.9-0.3-0.40.40.7-0.30.7-1.0-1.41.0-0.60.7-0.70.6-0.6-1.0-0.1-0.21.2-0.7
Locomotion distance, session 10.81.04.20.7-1.2-1.21.20.7-0.90.3-0.1-0.7-0.10.6-0.40.4-0.20.20.5-1.82.1-1.22.0
Locomotion velocity, session 20.91.03.90.80.00.00.00.60.20.6-1.3-1.31.3-1.10.8-0.80.8-0.8-1.40.5-1.02.0-1.7
Locomotion distance, session 20.81.12.31.4-1.2-1.21.21.4-1.11.0-1.2-1.51.2-0.60.6-0.60.9-0.9-1.0-1.21.00.70.3
Locomotion velocity, session 31.11.33.11.0-1.4-1.41.51.4-1.41.0-1.2-1.31.1-1.00.2-0.21.0-1.0-0.9-1.81.40.30.5
Locomotion distance, session 30.40.51.2-0.81.01.0-0.9-0.70.8-1.10.30.4-0.60.6-1.11.1-0.50.50.50.5-0.4-0.1-0.3
Stereotopy head waving bouts, day 30.50.61.80.4-0.9-0.90.81.1-0.70.6-0.8-1.31.1-0.30.2-0.20.6-0.6-0.9-0.90.80.80.0
Stereotopy head waving duration, day 32.12.65.11.8-1.8-1.81.71.9-1.61.8-1.8-2.31.9-1.31.5-1.51.6-1.6-1.8-1.30.91.3-0.2
Locomotion velocity, session 70.10.20.4-0.60.60.6-0.6-0.40.5-0.40.30.1-0.20.2-0.10.1-0.30.30.10.5-0.60.2-0.3
Locomotion distance, session 70.10.10.60.1-0.1-0.10.10.1-0.40.4-0.30.00.1-0.40.8-0.80.2-0.2-0.20.3-0.40.1-0.1
Stereotopy head waving bouts, day 70.10.10.6-0.0-0.4-0.40.40.3-0.30.4-0.5-0.30.2-0.7-0.20.20.2-0.2-0.2-0.80.5-0.00.1
Stereotopy head waving duration, day 70.20.21.10.1-0.4-0.40.40.3-0.30.2-0.2-0.50.1-0.4-0.50.50.0-0.0-0.0-1.10.9-0.20.4
Locomotion velocity, session 81.21.54.21.2-1.3-1.31.11.2-1.11.2-1.5-1.51.3-2.11.1-1.11.0-1.0-1.4-0.60.11.1-0.6
Locomotion distance, session 85.17.49.83.0-3.1-3.13.03.1-3.02.9-3.0-3.13.0-2.82.7-2.72.8-2.8-2.8-2.01.41.9-0.2
Degree of sensitization distance2.42.66.11.6-1.8-1.71.61.6-1.72.2-1.4-1.31.6-1.92.5-2.51.5-1.5-1.6-0.50.10.9-0.2
Degree of sensitization stereotypy0.10.10.3-0.1-0.00.00.0-0.20.10.00.10.1-0.3-0.3-0.60.6-0.20.20.2-0.40.3-0.40.2
Conditioned locomotion0.70.83.60.5-1.1-1.11.00.6-1.00.20.2-0.1-0.20.4-0.40.4-0.40.40.5-1.61.7-1.31.9
Cocaine response after cond. corrected1.11.62.6-1.51.21.3-1.2-1.51.2-1.31.31.3-1.61.1-1.41.4-1.61.61.50.2-0.2-1.30.5
Cocaine response after cond. not corrected1.52.23.6-1.61.41.4-1.3-1.71.3-1.51.51.6-1.91.5-1.61.6-1.81.81.80.2-0.1-1.70.8
Cocaine response before conditioning0.10.10.40.3-0.5-0.50.50.4-0.60.4-0.1-0.10.10.10.1-0.10.3-0.30.0-0.50.6-0.40.6
Saline control response0.20.30.60.7-0.3-0.20.30.5-0.30.5-0.7-0.70.6-0.80.1-0.10.5-0.5-0.7-0.40.00.7-0.5
Bone: connectivity density0.20.30.60.4-0.7-0.80.60.5-0.50.6-0.4-0.60.5-0.20.6-0.60.5-0.5-0.5-0.40.10.4-0.1
Bone: cortical apparent density0.30.52.0-1.40.90.9-0.9-0.70.8-0.70.40.6-0.50.3-0.80.8-0.50.50.40.7-0.5-0.0-0.3
Bone: cortical area1.72.74.4-1.31.61.6-1.5-1.81.7-2.02.01.9-1.91.8-2.12.1-1.61.61.90.6-0.1-1.50.6
Bone: cortical porosity0.10.10.50.70.0-0.0-0.00.00.10.40.0-0.30.10.40.7-0.7-0.00.0-0.10.2-0.30.2-0.2
Bone: cortical porosity0.20.20.91.0-0.5-0.50.50.3-0.40.70.1-0.20.10.20.7-0.70.1-0.1-0.0-0.40.3-0.30.4
Bone: cortical thickness1.32.23.6-1.51.41.4-1.3-1.61.4-1.71.81.7-1.81.9-1.71.7-1.51.51.80.40.1-1.50.8
Bone: cortical thickness0.80.93.5-0.7-1.0-1.01.00.4-1.00.70.81.0-0.40.50.2-0.2-0.50.50.6-1.51.6-1.51.9
Bone: cortical tissue density0.30.51.9-1.41.00.9-1.0-0.80.9-0.80.40.6-0.50.3-0.80.8-0.50.50.40.8-0.60.0-0.4
Condit. Reinf. active minus inactive responses1.01.12.8-0.41.71.7-1.5-1.11.5-0.90.90.3-0.60.3-0.90.9-0.80.80.41.5-1.60.4-1.1
Condit. Reinf. active-inactive response ratio1.11.24.41.40.60.6-0.5-0.10.50.5-0.7-0.90.6-1.10.8-0.80.9-0.9-1.01.4-2.01.6-2.1
Condit. Reinf. active responses0.60.81.6-0.81.31.2-1.1-0.81.1-0.71.00.6-0.50.3-1.01.0-1.11.10.50.8-0.90.1-0.4
Condit. Reinf. inactive responses0.91.22.5-1.50.60.5-0.6-0.70.5-0.91.01.2-1.10.9-1.41.4-1.61.61.2-0.30.5-1.31.2
Incentive salience index mean1.62.03.2-1.11.81.8-1.7-1.51.7-1.51.81.1-1.31.0-1.71.7-1.71.71.21.1-1.1-0.5-0.2
Condit. Reinf. lever presses1.32.04.7-1.30.90.8-0.8-1.00.8-1.41.81.2-1.41.4-2.22.2-1.91.91.6-0.40.7-1.51.4
Condit. Reinf. active minus inactive responses0.20.20.60.7-0.5-0.50.50.6-0.70.6-0.2-0.40.4-0.80.4-0.40.3-0.3-0.3-0.50.50.00.3
Condit. Reinf. active-inactive response ratio0.10.20.5-0.00.30.3-0.2-0.30.1-0.30.40.6-0.50.0-0.50.5-0.60.60.6-0.10.3-0.70.5
Condit. Reinf. active responses0.40.61.21.1-0.7-0.70.71.0-0.80.8-0.5-0.90.9-0.80.7-0.70.8-0.8-0.8-0.70.50.60.0
Condit. Reinf. inactive responses1.01.52.31.3-1.1-1.11.01.4-1.01.3-1.0-1.51.5-1.11.3-1.31.5-1.5-1.5-0.60.21.3-0.6
Condit. Reinf. lever presses0.20.20.80.2-0.7-0.70.60.5-0.70.60.2-0.20.3-0.90.3-0.30.0-0.0-0.2-0.70.6-0.20.5
Condit. Reinf. lever reinforcers received0.20.30.60.7-0.6-0.60.60.7-0.70.6-0.2-0.60.7-0.60.5-0.50.5-0.5-0.6-0.60.50.30.2
Conditioned reinforcement - actives0.00.21.7-1.30.40.2-0.20.10.3-0.00.50.10.30.3-0.30.3-0.10.1-0.20.0-0.00.6-0.3
Conditioned reinforcement - inactives0.20.51.9-1.40.90.7-0.6-0.50.5-0.41.00.8-0.40.8-0.50.5-0.80.80.40.4-0.2-0.10.0
Conditioned locomotion0.81.16.1-2.51.11.1-1.2-0.61.3-1.01.20.6-0.21.1-1.41.4-0.90.90.30.5-0.30.6-0.5
Patch foraging indifference point 0 sec1.23.37.0-1.12.52.5-2.3-2.62.2-1.71.31.6-2.10.7-0.80.8-1.41.41.52.6-2.6-0.8-1.3
Patch foraging indifference point AUC0.10.20.9-0.20.40.4-0.6-0.10.40.00.20.10.2-0.10.1-0.1-0.30.3-0.30.7-1.00.7-0.6
Delay disc. indifference point, 0s delay2.02.37.6-1.71.00.8-0.9-1.70.8-1.11.82.4-2.40.9-0.90.9-1.11.12.30.30.1-2.81.5
Delay disc. indifference point, 16s delay1.21.62.5-1.61.31.5-1.5-1.31.3-1.61.51.3-1.21.5-1.31.3-1.51.51.20.8-0.4-0.70.3
Delay disc. indifference point, 2s delay3.64.011.1-1.91.31.2-1.2-1.91.1-1.02.62.5-2.81.8-1.81.8-2.12.12.9-0.10.8-3.32.4
Delay disc. indifference point, 24s delay0.91.52.9-1.21.21.3-1.1-1.31.0-1.71.41.1-1.51.3-1.01.0-1.41.41.50.8-0.4-1.30.7
Delay disc. indifference point, 4s delay4.64.98.8-2.21.71.7-1.8-2.11.7-1.52.82.7-2.82.0-2.32.3-2.72.72.90.10.7-3.02.1
Delay disc. indifference point, 8s delay1.01.73.0-1.40.81.0-0.9-0.90.8-1.61.61.3-1.41.1-1.51.5-1.71.71.6-0.20.9-1.61.6
Indifference point function ln k0.10.20.9-0.4-0.0-0.00.2-0.1-0.1-0.30.50.5-0.50.6-0.40.4-0.40.40.6-0.50.6-0.90.9
Indifference point function log k0.10.20.9-0.4-0.0-0.00.2-0.1-0.1-0.30.50.5-0.50.6-0.40.4-0.40.40.6-0.50.6-0.90.9
Patch foraging total patch changes 0 sec1.23.57.8-1.02.62.6-2.4-2.62.3-1.71.41.6-2.00.6-0.80.8-1.41.41.42.8-2.8-0.6-1.5
Patch foraging total patch changes 12 sec1.21.75.9-0.41.71.7-1.8-1.71.7-0.90.70.9-1.10.2-0.10.1-0.60.60.62.4-2.40.1-1.6
Patch foraging total patch changes 18 sec1.12.56.8-0.72.22.2-2.2-2.12.0-1.41.21.5-1.4-0.2-0.60.6-1.01.00.92.6-2.4-0.0-1.7
Patch foraging total patch changes 24 sec0.31.13.30.9-0.1-0.10.10.3-0.30.9-1.0-0.70.8-1.81.5-1.51.0-1.0-1.21.0-1.31.2-1.6
Patch foraging total patch changes 6 sec1.83.07.0-1.02.42.4-2.3-2.22.4-1.51.31.3-1.51.0-0.80.8-1.21.21.12.6-2.6-0.1-1.6
Patch foraging time to switch 0 sec0.10.51.30.6-0.8-0.90.90.7-0.90.6-0.6-0.50.4-0.60.4-0.40.6-0.6-0.3-1.11.2-0.20.5
Patch foraging water rate 0 sec0.62.35.0-0.32.12.1-2.1-1.82.1-1.61.20.6-1.10.9-1.11.1-1.11.10.72.2-2.20.4-1.6
Patch foraging water rate 12 sec0.00.20.5-0.20.50.5-0.5-0.40.5-0.50.70.1-0.20.1-0.50.5-0.50.50.20.20.10.0-0.2
Patch foraging water rate 18 sec0.40.83.1-0.4-0.3-0.30.3-0.0-0.3-0.40.60.2-0.71.4-0.90.9-0.50.51.0-1.01.7-1.51.8
Patch foraging water rate 24 sec0.10.20.70.20.40.4-0.30.20.3-0.40.2-0.40.50.5-0.50.5-0.00.0-0.40.10.20.8-0.6
Patch foraging water rate 6 sec0.40.51.3-0.70.40.5-0.6-0.20.4-0.91.00.2-0.31.1-1.11.1-1.21.20.5-0.10.4-0.20.6
Seeking ratio, delayed vs. immediate footshock0.20.31.4-0.3-0.5-0.40.10.8-0.20.00.0-0.50.60.8-0.70.7-0.20.2-0.3-1.21.10.40.7
Distance traveled before self-admin0.00.10.30.50.10.1-0.2-0.30.2-0.50.2-0.0-0.1-0.3-0.10.1-0.10.10.00.4-0.50.1-0.3
Distance traveled after self-admin0.10.20.5-0.10.0-0.1-0.2-0.20.1-0.40.50.3-0.40.4-0.40.4-0.30.30.5-0.20.6-0.70.7
Extensor digitorum longus weight2.28.715.6-2.33.94.0-3.9-3.43.6-3.53.02.7-2.83.0-2.72.7-3.03.02.62.6-2.1-1.0-0.8
Bone: elastic displacement0.60.81.51.2-0.9-0.90.90.8-0.80.9-1.2-0.90.9-0.50.8-0.81.2-1.2-0.8-0.60.30.6-0.3
Bone: elastic work0.20.20.80.2-0.0-0.0-0.0-0.40.2-0.40.20.3-0.70.9-0.40.4-0.20.20.7-0.20.4-0.90.6
Bone: endosteal estimation0.00.10.40.2-0.0-0.00.1-0.30.1-0.30.60.4-0.4-0.2-0.30.3-0.40.40.4-0.0-0.0-0.50.3
Bone: endosteal perimeter0.61.63.0-1.20.90.9-0.8-1.10.8-1.51.71.7-1.40.9-1.61.6-1.51.51.50.00.4-1.41.0
Epididymis fat weight0.31.42.3-0.81.31.3-1.3-1.51.4-1.41.41.5-1.51.3-1.31.3-0.90.91.30.7-0.5-0.9-0.0
Delta time in closed arm before/after self-admin7.87.312.12.2-3.3-3.43.23.4-3.12.7-3.1-2.72.6-2.12.1-2.12.7-2.7-2.2-3.53.10.71.4
Delta time in open arm before/after self-admin4.35.08.6-2.12.52.6-2.8-2.82.8-2.82.02.0-2.11.6-1.91.9-2.02.01.62.9-2.8-0.2-1.6
Diff in mean of infusions in LGA sessions0.10.20.80.4-0.3-0.40.40.0-0.20.3-0.60.2-0.40.3-0.30.30.3-0.30.5-0.70.9-0.90.9
Delay discount exponential model param3.34.57.42.3-1.8-1.91.92.1-1.62.0-2.7-2.52.6-1.92.0-2.02.6-2.6-2.7-0.4-0.42.7-1.9
Extinction: sum of active levers before priming0.10.10.6-0.00.40.5-0.30.00.2-0.3-0.1-0.30.30.2-0.20.2-0.10.1-0.30.2-0.30.8-0.7
Active lever presses in extinction session 60.50.52.20.4-0.5-0.50.60.3-0.60.5-0.5-0.0-0.20.40.0-0.00.3-0.30.4-1.31.5-1.11.3
Bone: final force0.20.30.90.60.70.7-0.7-0.61.0-0.50.50.1-0.20.2-0.30.3-0.30.30.10.9-0.80.4-0.7
Bone: final moment0.30.41.20.50.90.9-0.9-0.81.1-0.60.60.3-0.40.4-0.40.4-0.50.50.31.0-0.80.2-0.7
Food consumed during 24 hour testing period0.71.43.3-0.61.81.8-1.7-1.21.8-1.00.70.3-0.50.3-0.60.6-0.80.80.21.8-1.70.8-1.5
Glucose8.813.941.2-1.45.55.4-5.4-3.45.4-2.81.20.7-0.80.4-0.80.8-1.61.6-0.26.4-6.43.6-5.8
Heart weight0.50.83.61.10.90.9-0.8-0.70.9-0.2-0.2-0.4-0.0-0.60.2-0.20.4-0.4-0.41.4-1.91.0-1.9
Delay discount hyperbolic model param3.84.88.22.3-1.8-1.91.92.1-1.62.0-2.8-2.62.7-2.12.2-2.22.7-2.7-2.8-0.3-0.52.9-2.0
Intermittent access intake day 1-15 change0.21.23.6-1.51.11.2-1.2-1.01.2-0.80.90.8-0.40.6-0.70.7-1.11.10.21.9-1.90.8-1.4
Intermittent access intake escalation0.21.23.6-1.51.11.1-1.2-1.01.2-0.80.90.8-0.40.6-0.70.7-1.11.10.21.7-1.90.7-1.2
Intermittent access intake escalation 20.30.52.8-0.90.50.5-0.6-0.50.6-0.50.20.30.00.2-0.10.1-0.50.5-0.21.5-1.70.8-1.1
Intermitt. access day 1 inactive lever presses0.00.21.2-0.3-0.1-0.40.50.7-0.50.20.2-0.00.4-0.10.2-0.20.1-0.1-0.2-0.91.1-0.10.7
Intermitt. access day 15 inactive lever presses0.42.34.9-1.72.21.9-1.8-1.51.7-1.61.81.3-0.81.3-1.21.2-1.61.60.61.9-1.80.6-1.3
Intermitt. access escalation Index0.20.53.10.50.20.3-0.5-0.60.5-0.0-0.00.2-0.0-0.10.2-0.20.0-0.0-0.31.5-1.70.8-1.5
Intermittent access day 1 total infusions0.10.42.2-0.8-0.1-0.30.20.2-0.2-0.00.50.4-0.40.7-0.30.3-0.30.30.6-0.91.2-1.11.5
Intermittent access day 15 total infusions0.61.44.6-2.21.21.1-1.2-1.21.3-1.01.31.3-0.91.3-1.11.1-1.31.30.81.3-1.2-0.2-0.4
Intermittent access terminal intake (last 3 days)0.40.72.6-1.60.80.6-0.8-0.80.9-0.60.80.7-0.40.7-0.50.5-0.80.80.21.3-1.50.4-0.8
Intermittent access total infusions0.50.62.7-1.60.60.5-0.7-0.60.7-0.70.90.8-0.61.1-0.70.7-0.80.80.60.5-0.5-0.30.1
Intermittent access day 1 locomotion0.50.84.40.5-0.7-0.80.71.3-0.70.4-0.3-1.10.90.4-0.10.10.4-0.4-0.4-2.02.10.01.2
Intermittent access day 15 total locomotion0.20.72.3-1.50.80.7-0.9-0.60.9-1.10.80.6-0.51.3-1.21.2-0.70.70.60.10.1-0.1-0.0
Intermittent access total locomotion0.60.72.5-1.60.70.6-0.8-0.50.8-1.10.90.4-0.51.4-1.11.1-0.80.80.7-0.10.4-0.30.4
Intermittent access standard deviation0.31.84.60.5-1.2-1.31.21.7-1.11.2-1.2-1.62.1-1.01.3-1.31.3-1.3-2.0-0.4-0.22.1-1.0
Left kidney weight0.10.61.80.10.00.00.0-0.40.1-0.90.90.3-0.91.2-1.01.0-0.50.51.1-0.51.2-1.31.3
Right kidney weight0.10.72.70.5-0.1-0.20.2-0.4-0.1-0.70.70.4-1.01.3-0.80.8-0.20.21.2-0.81.3-1.61.5
Cocaine induced anxiety0.82.33.6-1.31.71.7-1.9-1.81.9-1.81.31.1-1.31.6-1.51.5-1.51.51.11.7-1.6-0.1-1.0
Post-drug Anxiety2.12.44.0-1.51.71.7-1.7-2.01.7-1.71.41.9-1.81.7-1.51.5-1.41.41.61.4-1.2-1.1-0.2
Baseline Anxiety0.20.31.4-0.1-0.3-0.30.40.0-0.50.3-0.10.6-0.50.10.0-0.00.2-0.20.6-0.80.9-1.21.1
Tail length1.58.212.8-3.23.23.1-3.1-3.03.1-3.63.02.6-2.93.3-3.23.2-3.23.22.91.8-1.0-1.70.5
Length with tail2.08.913.4-2.93.13.1-3.2-3.33.3-3.73.53.0-3.23.0-3.33.3-3.43.43.21.9-1.1-2.20.6
Length without tail0.31.63.3-0.21.11.1-1.2-1.71.3-1.51.61.5-1.81.0-1.21.2-1.11.11.70.9-0.5-1.50.4
Times rat made contact with spout2.73.19.61.80.30.3-0.30.40.21.2-1.8-1.81.6-1.92.1-2.11.5-1.5-2.11.7-2.42.8-3.1
Lifetime Intake0.40.52.4-1.60.60.5-0.6-0.50.7-0.60.80.6-0.41.0-0.70.7-0.70.70.40.3-0.3-0.20.1
Liver weight, left0.40.81.51.0-1.1-1.21.21.1-1.20.7-0.3-1.10.70.20.8-0.80.7-0.7-0.4-1.01.1-0.10.9
Liver weight, right1.01.83.81.8-1.5-1.51.71.8-1.81.1-1.0-1.41.3-0.30.7-0.71.2-1.2-0.9-1.91.80.21.0
Locomotor activity0.50.73.6-0.61.01.0-1.0-0.81.0-0.40.20.3-0.2-0.10.1-0.1-0.20.2-0.11.7-1.90.7-1.5
Locomotor testing distance0.41.03.9-2.00.70.7-0.6-0.90.8-0.81.31.5-1.00.8-0.90.9-1.21.21.00.5-0.5-0.90.5
Locomotor testing rearing0.72.44.3-2.11.91.9-1.9-1.82.0-1.61.31.6-1.20.8-1.21.2-1.41.40.92.0-2.0-0.0-1.0
Locomotion in novel chamber2.43.36.61.9-2.6-2.52.31.4-2.22.0-1.7-0.90.5-1.91.9-1.91.9-1.9-0.4-1.91.7-1.21.5
Locomotion in novel chamber post-restriction0.82.54.41.4-2.0-2.02.02.0-2.11.7-1.3-1.31.5-1.51.4-1.41.4-1.4-1.2-2.01.80.30.9
Fecal boli incidents, locomotor time 10.10.31.40.9-0.3-0.30.20.5-0.40.5-0.7-1.20.60.20.1-0.10.3-0.3-0.5-0.40.40.5-0.1
Change in fecal boli incidents, locomotor task0.50.51.6-0.70.60.6-0.5-0.20.6-0.90.10.20.3-0.90.3-0.3-0.10.1-0.51.1-1.31.0-1.3
Time >=10cm from walls, locomotor time 10.20.30.70.4-0.7-0.70.80.3-0.60.0-0.6-0.30.2-0.40.5-0.50.8-0.8-0.2-0.40.2-0.20.1
Bouts of movement, locomotor time 10.60.72.4-1.50.70.6-0.6-1.00.8-0.51.21.3-0.8-0.40.4-0.4-0.50.50.51.5-1.3-0.3-0.6
Total resting periods, locomotor time 10.30.31.2-1.10.40.3-0.2-0.50.4-0.00.70.8-0.3-0.50.6-0.6-0.00.00.01.0-1.00.1-0.6
Rest time, locomotor task time 10.10.20.8-0.9-0.1-0.10.00.4-0.20.40.10.40.5-0.10.5-0.50.1-0.1-0.50.3-0.10.7-0.3
Distance moved, locomotor task time 10.10.30.90.30.60.6-0.6-0.50.6-0.80.2-0.0-0.40.7-1.01.0-0.50.50.40.2-0.1-0.1-0.0
Vertical activity count, locomotor time 10.00.10.20.40.30.3-0.2-0.40.3-0.50.1-0.2-0.30.3-0.40.4-0.10.10.30.1-0.3-0.1-0.1
Time >=10cm from walls, locomotor time 20.30.73.2-0.5-1.3-1.21.21.1-1.00.1-0.2-0.20.6-0.1-0.00.00.3-0.3-0.3-1.51.8-0.31.2
Bouts of movement, locomotor time 20.72.35.1-1.80.70.6-0.5-0.80.8-1.42.01.6-1.51.5-1.51.5-1.91.91.8-0.71.6-2.12.3
Total resting periods, locomotor time 20.62.24.0-1.80.90.8-0.7-0.90.9-1.62.01.7-1.51.3-1.51.5-2.02.01.8-0.41.2-1.91.9
Rest time, locomotor task time 20.20.41.20.8-0.0-0.10.20.3-0.10.3-0.5-0.20.7-0.60.7-0.70.8-0.8-0.80.5-0.81.1-1.1
Distance moved, locomotor task time 20.10.10.4-0.1-0.6-0.60.40.5-0.60.1-0.2-0.30.2-0.20.1-0.10.1-0.1-0.1-0.50.6-0.20.6
Vertical activity count, locomotor time 20.20.41.00.1-0.9-0.90.90.5-0.90.5-0.3-0.30.0-0.00.3-0.30.5-0.50.1-0.90.9-0.81.0
Light reinforcement 10.10.62.8-1.70.60.6-0.7-0.50.5-0.70.90.9-0.60.6-0.90.9-1.01.00.7-0.10.6-0.60.5
Light reinforcement 20.71.76.2-1.5-0.2-0.20.2-0.1-0.3-0.61.31.1-1.01.4-1.31.3-1.21.21.4-1.51.8-2.02.5
Bone: marrow area0.00.10.30.2-0.2-0.20.2-0.2-0.0-0.20.60.4-0.4-0.3-0.30.3-0.40.40.4-0.20.1-0.50.4
Bone: maximum diameter2.24.57.1-1.42.62.7-2.6-2.62.6-2.72.42.0-2.21.7-2.52.5-1.91.92.01.7-1.3-1.1-0.4
Bone: maximum force0.10.30.60.10.40.4-0.4-0.60.7-0.60.80.6-0.50.4-0.60.6-0.60.60.50.4-0.2-0.3-0.0
Bone: maximum moment0.20.40.70.00.60.6-0.6-0.80.8-0.70.80.7-0.70.6-0.80.8-0.70.70.70.5-0.2-0.40.0
Mean time between licks in bursts0.10.30.7-0.70.80.8-0.8-0.60.8-0.70.30.5-0.20.1-0.50.5-0.50.50.00.6-0.10.4-0.8
Mean num. licks in bursts2.15.812.23.5-1.1-1.11.22.0-1.22.2-2.7-3.02.8-2.62.8-2.82.7-2.7-3.00.1-0.73.3-2.5
Cd content in liver0.60.61.5-0.51.21.1-1.2-0.81.2-0.70.20.3-0.20.4-0.60.6-0.30.30.11.0-1.20.6-1.2
Co content in liver1.01.21.9-1.01.21.2-1.4-1.41.3-1.31.11.2-1.20.5-1.21.2-1.01.01.10.8-1.0-0.7-0.2
Cu content in liver0.20.21.00.50.60.6-0.7-0.30.7-0.2-0.1-0.40.1-0.0-0.10.10.0-0.0-0.30.7-0.70.8-1.0
Fe content in liver1.01.22.50.7-1.6-1.51.51.3-1.61.2-1.1-1.10.9-0.90.9-0.90.8-0.8-0.7-1.31.1-0.00.8
K content in liver2.12.15.0-1.80.60.7-0.7-1.10.8-1.81.61.4-1.52.2-1.91.9-1.51.51.7-0.11.1-1.61.5
Mg content in liver0.40.40.9-0.40.50.5-0.5-0.80.5-0.80.70.9-0.90.7-0.90.9-0.30.30.90.30.1-0.80.4
Mn content in liver0.40.41.4-0.60.40.4-0.4-0.30.3-0.80.40.2-0.40.9-1.21.2-0.80.80.6-0.40.3-0.50.6
Na content in liver2.22.45.1-2.21.41.4-1.4-1.81.5-1.71.92.1-1.81.4-1.41.4-1.71.71.71.1-0.4-1.30.5
Rb content in liver0.80.91.9-0.31.41.3-1.3-1.01.3-1.40.60.4-0.71.0-1.21.2-0.50.50.61.3-0.70.1-0.7
Se content in liver1.31.63.6-1.61.11.2-1.2-1.21.1-1.51.11.2-1.31.9-1.51.5-1.41.41.40.6-0.1-1.00.6
Sr content in liver3.73.26.5-1.21.81.9-2.0-2.52.0-1.91.71.9-2.51.6-1.51.5-1.71.72.31.4-0.8-1.90.3
Zn content in liver0.60.72.4-0.20.40.3-0.4-0.50.5-1.10.40.3-0.71.5-1.51.5-0.70.70.8-0.20.9-0.60.7
Bone: minimum diameter0.10.10.40.6-0.3-0.30.40.3-0.3-0.30.0-0.20.20.0-0.30.30.3-0.3-0.1-0.60.60.00.2
Time in familiar zone, hab. session 10.10.10.2-0.4-0.2-0.20.00.1-0.2-0.00.30.30.0-0.3-0.40.4-0.20.20.0-0.50.3-0.10.3
Time in novel zone, hab. session 10.20.20.70.40.60.6-0.4-0.30.4-0.1-0.5-0.20.00.30.3-0.30.3-0.3-0.20.8-0.70.5-0.8
Total zone transitions, hab. session 10.00.10.30.4-0.1-0.10.00.2-0.0-0.1-0.4-0.50.2-0.0-0.20.2-0.00.0-0.1-0.40.40.20.1
Total locomotion distance, hab. session 10.60.82.4-1.00.10.1-0.1-0.30.0-0.80.90.7-0.90.7-1.31.3-0.90.91.1-0.81.1-1.41.6
Locomotion velocity, hab. session 10.30.51.9-0.6-0.1-0.10.2-0.1-0.2-0.40.70.3-0.60.4-0.80.8-0.60.60.8-0.81.1-1.21.4
Time in familiar zone, hab. session 21.11.32.11.4-1.1-1.11.21.2-1.21.2-1.2-1.21.2-1.31.2-1.21.4-1.4-1.1-0.70.50.7-0.1
Time in novel zone, hab. session 21.11.22.6-1.01.41.4-1.6-1.31.6-1.10.80.8-0.81.2-0.80.8-1.11.10.61.4-1.30.1-0.9
Total zone transitions, hab. session 20.70.81.7-0.90.70.7-0.8-0.70.8-1.20.80.5-0.81.3-1.21.2-1.31.31.00.10.5-0.70.7
Total locomotion distance, hab. session 21.01.22.0-1.31.01.0-1.1-1.01.1-1.41.20.9-1.11.2-1.41.4-1.41.41.30.60.1-0.90.8
Locomotion velocity, hab. session 21.52.03.4-1.71.11.1-1.2-1.21.2-1.71.61.3-1.51.5-1.81.8-1.71.71.60.30.5-1.41.2
Novel to familiar place preference ratio0.10.10.4-0.50.50.5-0.5-0.20.5-0.2-0.10.00.1-0.10.0-0.0-0.20.2-0.20.6-0.50.6-0.6
Novelty place preference0.10.20.7-0.40.50.5-0.5-0.10.5-0.1-0.3-0.10.3-0.10.2-0.2-0.00.0-0.40.6-0.60.8-0.8
Time in novel zone, NPP test0.20.21.0-0.20.50.5-0.5-0.10.5-0.1-0.5-0.20.3-0.10.3-0.30.1-0.1-0.50.8-0.80.9-1.0
Total zone transitions, NPP test0.40.62.50.7-0.8-0.80.80.4-0.80.0-0.2-0.1-0.20.5-0.30.3-0.10.10.5-1.31.6-1.11.5
Total locomotion distance, NPP test0.70.93.9-0.9-0.4-0.40.4-0.0-0.4-0.50.80.8-0.81.2-0.90.9-0.70.71.1-1.01.6-1.62.0
Locomotion velocity, NPP test0.81.14.1-1.1-0.2-0.20.2-0.2-0.2-0.71.01.0-0.91.3-1.11.1-1.01.01.3-0.91.5-1.72.0
Intraocular pressure0.30.51.7-1.30.70.6-0.8-0.70.9-0.90.20.7-0.50.3-1.11.1-0.70.70.50.6-0.8-0.1-0.3
Delta distance traveled before/after self-admin0.40.52.0-0.0-0.8-0.80.80.7-0.80.7-0.5-0.10.20.10.5-0.50.4-0.4-0.0-1.01.4-0.61.2
Delta ambulatory time before/after self-admin0.30.51.90.4-0.8-0.80.80.7-0.90.9-0.6-0.20.20.10.6-0.60.5-0.50.0-1.01.4-0.71.2
Parametrial fat weight1.12.56.4-0.52.22.3-2.3-1.62.2-1.61.60.5-0.71.3-0.90.9-1.11.10.42.5-2.31.1-1.8
Pavlov. Cond. lever latency0.10.20.8-0.10.40.5-0.4-0.40.5-0.2-0.10.3-0.1-0.20.3-0.30.2-0.2-0.10.8-0.90.3-0.8
Pavlov. Cond. magazine entry latency1.11.42.51.3-1.4-1.51.61.4-1.51.5-0.7-1.31.2-1.10.9-0.90.9-0.9-1.1-1.30.90.50.3
Pavlov. Cond. change in total contacts1.31.42.4-0.91.41.4-1.4-1.21.5-1.31.20.8-1.01.1-1.61.6-1.51.50.91.0-0.7-0.3-0.2
Pavlov. Cond. index score0.70.91.80.9-1.3-1.31.31.2-1.31.1-0.5-1.00.8-0.50.4-0.40.5-0.5-0.6-1.31.20.10.7
Pavlov. Cond. latency score0.60.81.60.8-1.2-1.21.21.1-1.20.9-0.5-1.00.8-0.40.4-0.40.4-0.4-0.6-1.31.20.10.8
Pavlov. Cond. lever contacts0.20.31.00.3-0.6-0.70.70.7-0.70.4-0.1-0.50.4-0.0-0.20.2-0.10.1-0.2-1.01.0-0.10.8
Pavlov. Cond. magazine entry number1.01.32.1-1.41.21.2-1.3-1.41.2-1.30.81.4-1.41.2-1.01.0-1.01.01.30.8-0.5-1.00.2
Pavlov. Cond. intertrial magazine entries1.82.15.4-1.60.20.2-0.2-0.70.2-0.82.01.7-1.51.5-1.51.5-2.02.01.8-0.71.2-2.22.3
Pavlov. Cond. lever-magazine prob. diff.0.91.12.21.0-1.4-1.41.51.3-1.41.2-0.6-1.21.0-0.60.5-0.50.6-0.6-0.7-1.41.30.10.8
Pavlov. Cond. response bias0.20.30.90.6-0.6-0.60.80.7-0.70.5-0.0-0.70.5-0.3-0.10.10.1-0.1-0.3-0.90.90.10.5
Pavlov. Cond. lever latency2.94.17.8-2.11.81.8-1.8-2.11.8-2.51.72.1-2.42.8-2.52.5-2.02.02.50.70.1-2.01.1
Pavlov. Cond. magazine entry latency0.10.10.5-0.4-0.4-0.40.30.2-0.30.30.30.20.1-0.70.3-0.3-0.10.1-0.1-0.20.1-0.10.2
Pavlov. Cond. change in total contacts0.10.30.60.7-0.6-0.50.50.6-0.60.8-0.2-0.60.7-0.80.7-0.70.4-0.4-0.6-0.30.10.5-0.1
Pavlov. Cond. index score0.81.23.01.0-1.2-1.11.21.2-1.11.4-0.6-1.01.2-1.71.5-1.51.0-1.0-1.3-0.60.20.9-0.3
Pavlov. Cond. latency score0.81.32.71.0-1.3-1.31.31.3-1.21.5-0.6-1.01.2-1.61.4-1.41.0-1.0-1.2-0.80.40.7-0.1
Pavlov. Cond. lever contacts2.94.38.42.0-2.0-2.02.02.3-2.02.6-1.8-2.22.5-2.92.5-2.52.0-2.0-2.5-1.00.22.0-0.9
Pavlov. Cond. magazine entry number0.50.61.8-0.50.20.2-0.2-0.40.1-0.70.40.5-0.81.3-1.21.2-0.80.81.0-0.60.9-1.21.2
Pavlov. Cond. intertrial magazine entries0.00.10.30.10.50.5-0.4-0.30.3-0.5-0.10.1-0.30.5-0.40.4-0.10.10.30.2-0.1-0.1-0.0
Pavlov. Cond. lever-magazine prob. diff.1.01.53.21.1-1.3-1.31.31.3-1.21.5-0.7-1.11.3-1.81.6-1.61.2-1.2-1.3-0.60.20.9-0.3
Pavlov. Cond. response bias1.92.65.81.5-1.4-1.41.41.6-1.32.0-1.3-1.71.9-2.42.1-2.11.5-1.5-2.0-0.4-0.31.7-1.0
Time in closed arm before self-admin0.20.31.0-0.30.60.7-0.5-0.40.5-0.40.70.4-0.41.0-0.40.4-0.70.70.40.4-0.0-0.20.2
Time in closed arm after self-admin1.31.53.30.5-1.5-1.41.61.7-1.51.4-1.2-1.01.2-0.61.0-1.01.0-1.0-0.9-1.71.80.11.2
Time in open arm before self-admin0.60.72.00.3-1.1-1.21.10.9-1.11.4-0.4-0.20.4-0.70.8-0.80.4-0.4-0.3-1.21.1-0.51.1
Time in open arm after self-admin0.40.41.2-0.40.60.6-0.9-0.60.8-0.70.60.1-0.10.1-0.50.5-0.50.5-0.10.9-1.10.8-1.1
Bone: periosteal estimation0.41.02.0-0.40.70.8-0.7-1.10.9-1.31.41.2-1.20.8-1.31.3-1.11.11.20.2-0.0-1.10.5
Bone: periosteal perimeter1.42.74.6-1.51.31.3-1.2-1.61.3-2.12.02.0-2.01.6-2.12.1-1.71.72.00.10.4-1.91.1
Bone: post-yield work0.10.20.6-0.20.10.1-0.1-0.30.1-0.10.70.7-0.50.0-0.40.4-0.50.50.5-0.30.3-0.60.5
Progressive ratio test 1 active lever presses0.30.52.5-1.60.40.3-0.4-0.10.4-0.70.90.5-0.31.2-0.70.7-0.80.80.5-0.20.4-0.40.8
Progressive ratio test 1 breakpoint0.30.52.6-1.60.50.4-0.4-0.10.5-0.81.00.6-0.31.2-0.80.8-0.80.80.5-0.20.5-0.40.8
Progressive ratio test 1 inactive lever presses1.64.27.4-2.72.32.2-2.1-1.52.1-2.32.71.8-1.52.7-2.62.6-2.42.41.70.50.2-0.80.7
Progressive ratio test 2 active lever presses0.50.73.7-1.90.60.4-0.6-0.80.6-0.71.11.2-0.80.9-0.50.5-0.70.70.80.6-0.4-0.70.3
Progressive ratio test 2 breakpoint0.50.63.1-1.80.60.4-0.6-0.80.5-0.61.01.1-0.80.8-0.40.4-0.70.70.80.6-0.5-0.70.2
Progressive ratio test 2 inactive lever presses0.41.44.5-2.11.31.0-1.1-0.81.1-1.31.81.4-0.81.6-1.31.3-1.31.30.90.30.1-0.50.4
Incentive Sensitization - Responses0.20.61.8-0.90.70.5-0.6-1.20.6-0.31.01.4-1.20.3-0.40.4-0.50.51.00.8-0.7-1.00.0
Incentive Sensitization - Breakpoint0.20.51.8-0.80.60.4-0.6-1.10.5-0.20.91.3-1.20.1-0.30.3-0.40.40.90.8-0.8-0.9-0.0
Sum of active levers in priming session hrs 5-60.60.61.5-0.40.60.6-0.7-0.90.5-0.60.50.8-1.11.2-0.80.8-0.60.61.10.00.2-1.10.6
Progressive ratio0.10.31.10.6-0.6-0.60.50.7-0.8-0.1-0.5-0.70.50.30.1-0.10.5-0.5-0.3-1.00.90.10.5
Food seeking constrained by brief footshock2.83.45.5-2.31.31.3-1.3-1.41.5-2.22.22.2-1.92.3-2.42.4-1.91.92.2-0.21.0-2.01.7
Seeking ratio, punishment vs. effort1.02.34.6-2.21.41.4-1.3-1.41.6-1.22.01.8-1.61.2-1.61.6-1.91.91.60.60.2-1.40.9
Retroperitoneal fat weight0.41.93.3-1.21.81.8-1.8-1.61.8-1.51.61.3-1.11.0-1.21.2-1.11.11.01.6-1.3-0.1-0.8
Reaction time number correct0.00.10.90.20.30.3-0.3-0.10.3-0.1-0.4-0.30.2-0.40.3-0.30.1-0.1-0.40.4-0.40.7-0.9
Reaction time mean minus median0.42.84.92.0-1.4-1.41.41.3-1.41.9-2.1-1.51.5-2.22.1-2.12.2-2.2-1.7-0.2-0.11.3-1.1
Reaction time mean minus median AUC0.32.03.61.5-1.4-1.51.31.1-1.21.8-1.5-1.11.2-1.91.9-1.91.7-1.7-1.4-0.30.00.9-0.7
Reaction time num false alarms1.01.75.2-2.31.31.3-1.1-1.31.1-1.41.31.8-1.51.4-1.21.2-1.31.31.50.6-0.2-1.40.7
Reaction time num false alarms AUC0.81.94.4-2.11.11.1-0.9-1.40.9-1.31.41.9-1.81.6-1.31.3-1.21.21.90.30.2-2.01.3
Reaction time trials correct on left0.00.10.90.20.30.3-0.3-0.10.3-0.1-0.4-0.30.2-0.40.3-0.30.1-0.1-0.40.4-0.40.7-0.9
Reaction time trials on left0.00.20.90.20.30.3-0.2-0.10.3-0.1-0.5-0.30.3-0.50.3-0.30.2-0.2-0.40.4-0.40.7-0.9
Reaction time mean0.51.12.50.9-1.3-1.41.21.0-1.21.1-1.5-0.60.8-0.70.9-0.91.6-1.6-0.8-0.60.30.30.0
Reaction time mean AUC0.61.53.01.0-1.6-1.61.61.2-1.51.4-1.6-0.70.9-0.91.0-1.01.7-1.7-0.9-1.00.70.20.3
Median of all reaction times0.40.71.60.5-1.2-1.21.10.9-1.00.8-1.2-0.40.6-0.20.4-0.41.3-1.3-0.5-0.70.40.10.3
Reaction time omissions0.71.12.10.8-1.2-1.21.20.9-1.11.2-1.4-0.70.8-1.01.3-1.31.4-1.4-0.8-0.50.00.4-0.2
Reaction time false alarm rate1.52.15.0-2.20.90.9-0.7-1.30.7-1.21.51.9-1.91.7-1.31.3-1.31.32.00.10.4-2.21.7
Reaction time premature initiation rate1.62.54.52.0-2.0-2.01.92.1-2.01.8-1.2-1.61.7-1.01.3-1.31.2-1.2-1.4-1.91.50.50.8
Reaction time premature initiations0.51.63.61.9-1.4-1.41.31.6-1.41.4-1.2-1.41.5-1.01.2-1.21.0-1.0-1.3-1.30.80.80.1
Std. dev. reaction times0.61.84.01.5-1.3-1.31.41.0-1.31.6-1.8-1.01.1-1.61.7-1.72.0-2.0-1.2-0.40.00.7-0.5
Reaction time trials completed0.00.20.90.20.30.3-0.2-0.10.3-0.1-0.5-0.30.3-0.50.3-0.30.2-0.2-0.40.4-0.40.7-0.9
Reaction time trials AUC0.00.10.70.20.30.4-0.3-0.20.4-0.2-0.3-0.20.1-0.30.2-0.20.1-0.1-0.30.3-0.30.6-0.8
Run reversals in cocaine runway, females0.60.62.8-0.7-0.9-0.90.70.2-0.70.20.50.9-0.5-0.50.2-0.20.0-0.00.6-0.91.3-1.51.7
Run reversals in cocaine runway, males0.10.20.8-0.90.40.5-0.5-0.10.5-0.30.30.10.20.1-0.30.3-0.30.3-0.20.4-0.20.6-0.5
Latency to leave start box in cocaine runway0.40.61.4-0.70.50.6-0.6-1.00.7-0.60.81.0-1.20.7-0.90.9-0.60.61.10.3-0.3-1.10.6
Latency to leave start box in cocaine runway, F1.72.14.5-1.81.01.0-1.1-1.81.1-1.51.62.1-2.11.3-1.31.3-1.21.22.00.6-0.4-2.11.0
Latency to leave start box in cocaine runway, M0.50.41.61.3-0.5-0.30.30.7-0.31.0-0.8-1.10.9-0.40.2-0.20.5-0.5-0.8-0.40.10.9-0.4
Std. dev. time between licks in bursts0.10.20.7-0.80.30.3-0.3-0.20.2-0.20.80.8-0.1-0.1-0.10.1-0.70.70.1-0.10.4-0.10.0
Total sessions with >9 infusions1.01.32.60.7-1.2-1.21.31.6-1.21.4-0.8-1.41.5-0.90.9-0.91.0-1.0-1.2-1.31.00.80.3
Short access day 1 total inactive lever presses1.02.03.7-1.51.51.5-1.7-1.31.8-1.91.61.0-0.91.9-1.81.8-1.61.60.91.1-0.60.0-0.3
Short access day 10 total inactive lever presses0.00.20.8-0.90.30.2-0.40.30.3-0.60.3-0.10.50.6-0.50.5-0.40.4-0.3-0.10.10.8-0.1
Short access day 1 total infusions0.61.22.61.0-1.1-1.21.11.6-1.00.9-1.0-1.51.5-0.70.6-0.61.0-1.0-1.2-1.51.40.90.3
Short access day 10 total infusions0.20.41.1-0.3-0.5-0.70.80.8-0.70.90.0-0.30.5-0.30.5-0.50.3-0.3-0.3-1.11.0-0.20.9
Short access total infusions0.10.10.3-0.2-0.2-0.40.30.6-0.20.3-0.1-0.50.50.10.1-0.10.1-0.1-0.4-0.50.40.40.1
Short access day 1 locomotion0.81.44.90.8-1.2-1.21.21.6-1.11.1-1.0-1.41.0-0.50.4-0.40.9-0.9-0.6-2.12.2-0.01.3
Short access day 10 total locomotion0.62.37.10.9-1.6-1.51.52.3-1.50.7-1.1-2.01.8-0.50.6-0.61.1-1.1-1.2-2.72.60.61.4
Short access total locomotion1.42.14.71.0-1.5-1.61.52.2-1.51.2-1.2-2.11.9-0.90.9-0.91.2-1.2-1.5-2.01.81.10.6
One hour access (0.3 mA shock)0.60.74.2-2.10.90.5-0.6-0.50.7-1.01.00.8-0.51.4-0.90.9-0.70.70.60.20.1-0.30.4
Compulsive drug intake0.91.32.91.4-1.1-1.31.41.0-1.41.4-1.2-0.80.6-1.71.3-1.31.3-1.3-0.6-1.00.8-0.30.6
One hour access (shock baseline)0.30.72.5-1.60.70.6-0.8-0.60.8-1.10.90.7-0.41.5-0.90.9-0.80.80.50.4-0.2-0.0-0.0
Social response proportion0.50.72.4-0.51.01.0-1.0-0.81.1-1.10.90.3-0.61.6-0.70.7-0.90.90.60.7-0.30.0-0.2
Social responses1.62.04.0-1.71.91.9-2.0-1.51.9-1.71.11.0-0.91.3-1.01.0-1.31.30.72.0-1.20.4-1.2
Social time0.20.21.0-0.20.60.6-0.8-0.50.7-0.6-0.3-0.2-0.00.3-0.10.10.1-0.1-0.10.9-0.50.7-1.0
Soleus weight1.03.05.6-1.81.31.2-1.3-1.61.1-2.12.02.0-2.02.4-2.32.3-1.61.62.1-0.20.8-2.01.4
Bone: stiffness0.10.10.30.5-0.2-0.30.30.5-0.20.30.1-0.10.5-0.60.1-0.10.2-0.2-0.5-0.10.10.5-0.1
Tibialis anterior weight0.93.15.3-1.12.22.2-2.3-2.32.2-1.81.91.9-2.01.3-1.51.5-1.61.61.71.7-1.5-1.0-0.4
Time to tail flick, vehicle, before self-admin0.30.32.0-0.2-0.00.10.10.3-0.1-0.30.1-0.1-0.00.8-0.70.7-0.20.20.3-1.11.4-0.41.1
Time to tail flick, vehicle, after self-admin0.10.20.7-0.7-0.5-0.30.20.0-0.0-0.7-0.20.4-0.30.6-0.20.20.2-0.20.4-0.40.7-0.70.8
Time to tail flick, test, before self-admin0.30.41.01.0-0.3-0.30.20.3-0.40.7-0.8-0.70.5-0.50.8-0.80.5-0.5-0.70.4-0.80.7-0.8
Time to tail flick, test, after self-admin2.52.65.6-1.81.61.7-1.5-1.31.7-1.71.81.2-1.42.4-2.12.1-2.02.01.60.30.2-1.00.9
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.0-0.7-0.70.60.1-0.40.0-0.20.3-0.2-0.20.4-0.40.3-0.30.2-0.20.4-0.70.6
Delta time to tail flick, test, before/after SA1.31.63.4-1.91.21.3-1.1-1.01.4-1.61.61.1-1.01.5-1.71.7-1.41.41.10.30.2-0.60.5
Tibia length0.41.14.1-0.5-0.9-0.90.90.1-0.7-0.31.10.7-0.71.1-0.90.9-0.80.81.0-1.41.6-1.72.0
Ambulatory time before self-admin0.10.41.0-0.50.50.5-0.6-0.70.6-1.00.80.7-0.70.2-0.70.7-0.60.60.60.5-0.6-0.4-0.1
Ambulatory time after self-admin0.10.10.80.2-0.2-0.30.10.1-0.2-0.10.30.0-0.20.4-0.20.2-0.10.10.4-0.60.8-0.60.9
Bone: tissue strength0.80.82.71.10.20.2-0.20.20.20.5-0.8-0.70.8-1.30.8-0.80.9-0.9-1.01.0-1.31.4-1.6
Total heroin consumption0.20.22.51.6-0.1-0.20.20.2-0.20.3-0.5-0.70.30.40.3-0.30.3-0.3-0.3-0.10.10.3-0.3
Bone: trabecular number0.00.00.10.2-0.2-0.30.20.1-0.10.2-0.1-0.20.10.30.1-0.10.1-0.1-0.1-0.30.10.00.0
Bone: trabecular spacing0.71.12.2-1.51.21.2-1.0-1.10.9-1.01.21.4-1.10.8-0.90.9-1.21.21.10.8-0.4-0.80.2
Bone: trabecular thickness0.50.71.80.5-1.3-1.31.10.8-1.10.7-0.1-0.40.2-0.20.3-0.30.2-0.2-0.0-1.41.3-0.71.3
Bone: trabecular tissue density0.61.02.81.5-0.7-0.70.70.8-0.61.2-1.3-1.21.0-1.71.3-1.31.0-1.0-1.00.1-0.30.9-0.7
Water consumed over 24 hours0.50.93.8-0.71.31.3-1.3-0.81.2-0.40.30.1-0.1-0.10.2-0.2-0.50.5-0.21.6-1.91.0-1.6
Number of responses in last shaping day0.10.21.10.5-0.1-0.20.20.5-0.10.10.2-0.30.3-0.1-0.20.2-0.00.0-0.1-0.81.1-0.00.6