Hub : Genes

Zfp950l11

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	Zfp950l11	0.02	0.01	6.6e-04	0.01	0.02	0.01	0.01	1.6e-02	1.5e-03	4.5e-02	8.4e-03
2	NAcc	mRNA stability	Zfp950l11	0.07	0.03	4.8e-08	0.05	0.04	0.04	0.04	8.5e-08	2.8e-07	1.5e-06	5.7e-07
3	BLA	gene expression	Zfp950l11	0.09	0.05	3.5e-04	0.09	0.06	0.07	0.07	2.2e-05	2.4e-04	1.1e-04	1.3e-04
4	LHb	mRNA stability	Zfp950l11	0.31	0.13	3.4e-04	0.17	0.15	0.13	0.13	9.6e-05	1.9e-04	5.9e-04	5.9e-04
5	OFC	mRNA stability	Zfp950l11	0.27	0.16	5.8e-03	0.08	0.07	0	0.04	5.9e-03	1.1e-02	2.6e-01	3.9e-02
6	Brain	mRNA stability	Zfp950l11	0.09	0.04	3.5e-10	0.11	0.11	0.08	0.11	3.8e-10	2.5e-10	3.1e-08	3.2e-10
7	LHb	gene expression	Zfp950l11	0.28	0.14	2.2e-03	0.06	0.08	0.06	0.06	1.4e-02	7.3e-03	1.5e-02	1.2e-02
8	Brain	gene expression	Zfp950l11	0.1	0.04	9.9e-09	0.09	0.09	0.1	0.09	2.1e-08	7.5e-09	3.6e-09	4.5e-09
9	NAcc	gene expression	Zfp950l11	0.03	0.02	1.1e-03	0.01	0.01	0.01	0.01	4.1e-03	2.2e-03	1.4e-02	5.0e-03
10	pVTA	mRNA stability	Zfp950l11	0.05	0.03	4.9e-03	0.01	0.03	0.02	0.01	2.8e-02	3.3e-03	1.6e-02	2.2e-02
11	PL	gene expression	Zfp950l11	0.05	0.03	3.4e-05	0.03	0.04	0.02	0.03	1.5e-04	6.2e-05	5.3e-03	1.5e-04
12	pVTA	gene expression	Zfp950l11	0.09	0.05	1.4e-03	0.01	0.02	0.03	0.01	2.2e-02	6.3e-03	1.0e-03	4.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bone: apparent density	0.1	0.1	0.4	0.6	0.4	0.4	0.5	0.4	-0.5	-0.4	0.2	0.0	0.1	-0.2	0.2
Area under the delay curve	1.5	2.3	3.9	-2.0	-1.8	-1.8	-1.5	-1.9	1.7	1.0	-1.3	1.4	1.3	1.4	-0.5
BMI with tail	0.3	0.9	2.6	1.6	1.0	1.0	1.2	1.3	-1.0	-0.5	0.2	-0.2	0.1	-0.2	-1.2
BMI without tail	0.2	0.9	5.8	2.4	0.7	0.7	0.9	0.9	-1.2	0.4	-0.1	0.4	0.4	-0.3	-0.4
Body weight	0.7	2.9	10.9	3.3	2.0	2.0	2.2	2.0	-2.0	-0.6	0.5	-0.6	-0.2	-0.7	-1.3
Weight adjusted by age	1.0	3.0	5.9	2.4	2.2	2.2	1.9	2.2	-2.0	-1.5	1.2	-1.1	-0.9	-1.3	0.2
Bone surface	0.1	0.2	0.6	0.8	0.5	0.5	0.4	0.4	-0.4	-0.1	0.0	0.1	0.2	-0.0	-0.5
Bone volume	0.1	0.2	0.7	0.8	0.6	0.6	0.6	0.6	-0.6	-0.3	0.1	-0.1	-0.0	-0.2	-0.2
Breakpoint value in progressive ratio session	0.2	0.4	3.0	-0.4	-0.2	-0.2	0.1	-0.2	0.6	0.5	-0.2	0.1	0.3	0.8	-1.7
Number of licking bursts	0.0	0.1	0.2	0.2	-0.4	-0.4	-0.2	-0.2	0.0	0.3	-0.2	0.3	0.2	0.1	0.5
Context. condit. distance diff. score	0.4	0.5	1.0	0.4	-0.5	-0.5	-0.7	-0.5	0.3	1.0	-1.0	0.9	0.9	0.7	-0.4
Locomotion velocity, session 1	0.8	0.9	2.2	-0.6	0.8	0.8	0.6	0.7	-0.4	-1.4	1.1	-1.5	-1.4	-1.0	0.8
Locomotion distance, session 1	1.0	1.3	1.7	-1.2	-1.1	-1.1	-1.1	-1.1	1.2	0.8	-1.2	1.2	1.3	1.3	-1.3
Locomotion velocity, session 2	2.0	2.4	5.6	-2.4	-1.8	-1.8	-1.7	-1.8	1.9	1.0	-1.2	1.1	1.1	1.4	-1.1
Locomotion distance, session 2	1.0	1.4	2.3	-0.6	-1.2	-1.2	-1.1	-1.2	1.0	1.1	-1.3	1.5	1.5	1.2	-0.8
Locomotion velocity, session 3	1.0	1.2	3.9	-2.0	-1.3	-1.3	-1.4	-1.2	1.3	0.3	-0.4	0.7	0.7	0.8	-0.3
Locomotion distance, session 3	2.6	3.0	6.6	-2.6	-2.0	-2.0	-1.9	-1.9	2.0	1.0	-1.2	1.4	1.3	1.6	-1.2
Stereotopy head waving bouts, day 3	0.2	0.2	0.4	0.0	0.5	0.5	0.2	0.6	-0.3	-0.7	0.5	-0.5	-0.4	-0.3	-0.1
Stereotopy head waving duration, day 3	0.0	0.0	0.2	0.1	0.2	0.2	-0.0	0.3	-0.1	-0.2	0.1	-0.1	0.0	0.1	-0.4
Locomotion velocity, session 7	1.0	1.1	1.7	-1.2	-1.3	-1.3	-1.0	-1.0	1.2	0.9	-0.9	1.0	1.0	1.0	-0.8
Locomotion distance, session 7	3.7	4.7	6.6	-2.5	-2.6	-2.6	-2.6	-2.2	2.4	1.9	-1.9	1.9	1.8	2.0	-1.3
Stereotopy head waving bouts, day 7	0.4	0.4	1.5	1.2	0.9	0.9	0.5	0.8	-0.7	-0.2	0.1	-0.2	-0.1	-0.1	-0.7
Stereotopy head waving duration, day 7	0.3	0.3	1.2	1.1	0.8	0.8	0.4	0.8	-0.7	-0.4	0.2	-0.2	-0.1	-0.2	-0.3
Locomotion velocity, session 8	0.8	1.0	2.0	-0.8	-1.1	-1.1	-1.0	-1.0	0.8	0.5	-0.9	1.4	1.4	1.0	-0.6
Locomotion distance, session 8	2.3	3.4	6.3	-0.1	-1.6	-1.6	-1.7	-1.6	1.3	2.2	-2.3	2.5	2.5	1.9	-1.5
Degree of sensitization distance	0.1	0.1	0.4	0.6	0.2	0.2	0.0	0.2	-0.4	0.2	0.0	-0.1	-0.2	-0.3	0.6
Degree of sensitization stereotypy	0.2	0.2	0.9	0.9	0.5	0.5	0.2	0.5	-0.4	0.1	-0.2	0.1	0.2	0.1	-0.6
Conditioned locomotion	0.8	0.9	4.1	2.0	1.1	1.1	0.9	0.9	-1.3	-0.2	0.2	-0.1	-0.1	-0.6	0.6
Cocaine response after cond. corrected	0.1	0.1	0.3	-0.5	0.0	0.0	0.1	0.0	0.0	-0.5	0.3	-0.5	-0.5	-0.3	0.4
Cocaine response after cond. not corrected	0.2	0.3	1.2	-1.1	-0.6	-0.6	-0.5	-0.6	0.7	0.1	-0.2	0.1	0.0	0.3	-0.1
Cocaine response before conditioning	2.1	2.6	3.1	-1.3	-1.8	-1.8	-1.6	-1.6	1.6	1.7	-1.5	1.7	1.6	1.7	-1.3
Saline control response	0.5	0.7	3.8	0.9	0.4	0.4	0.4	0.3	-0.9	-0.5	0.5	-0.2	-0.4	-1.0	1.9
Bone: connectivity density	0.1	0.2	0.7	-0.1	-0.5	-0.5	-0.4	-0.4	0.2	0.3	-0.5	0.8	0.8	0.4	-0.0
Bone: cortical apparent density	0.7	1.1	4.9	-2.2	-1.2	-1.2	-1.4	-1.3	1.3	0.2	-0.3	0.3	0.2	0.5	0.1
Bone: cortical area	2.6	4.2	12.1	3.5	2.4	2.4	2.7	2.4	-2.6	-1.6	1.4	-0.5	-0.3	-1.1	-0.5
Bone: cortical porosity	1.7	1.9	2.9	1.3	1.5	1.5	1.7	1.7	-1.2	-1.0	1.5	-1.6	-1.5	-1.1	-0.3
Bone: cortical porosity	1.9	2.1	3.5	1.5	1.5	1.5	1.9	1.7	-1.4	-1.0	1.6	-1.5	-1.4	-1.2	0.1
Bone: cortical thickness	4.3	7.2	12.0	3.5	3.0	3.0	3.3	3.1	-3.3	-2.8	2.5	-1.7	-1.5	-2.2	1.1
Bone: cortical thickness	2.3	2.8	3.9	1.8	1.8	1.8	2.0	1.9	-1.9	-1.7	1.7	-1.3	-1.2	-1.5	1.1
Bone: cortical tissue density	0.7	1.1	5.3	-2.3	-1.1	-1.1	-1.4	-1.2	1.3	0.1	-0.3	0.1	0.0	0.4	0.3
Condit. Reinf. active minus inactive responses	1.1	1.3	3.1	1.8	1.4	1.4	1.3	1.1	-1.5	-0.9	0.7	-0.7	-0.6	-1.0	0.5
Condit. Reinf. active-inactive response ratio	0.6	0.6	1.1	1.0	0.9	0.9	0.9	0.8	-1.0	-1.0	0.7	-0.2	-0.1	-0.6	0.4
Condit. Reinf. active responses	1.4	1.8	5.5	2.3	1.5	1.5	1.6	1.3	-1.7	-0.7	0.6	-0.8	-0.8	-1.2	0.7
Condit. Reinf. inactive responses	0.3	0.4	1.3	1.1	0.6	0.6	0.7	0.5	-0.7	0.1	0.0	-0.5	-0.6	-0.6	0.4
Incentive salience index mean	0.5	0.6	2.2	1.5	0.9	0.9	1.1	0.7	-1.0	-0.4	0.3	-0.3	-0.2	-0.6	0.2
Condit. Reinf. lever presses	0.2	0.3	0.8	-0.1	-0.5	-0.5	-0.3	-0.6	0.5	0.9	-0.9	0.5	0.5	0.6	-0.6
Condit. Reinf. active minus inactive responses	0.4	0.6	1.7	1.3	0.9	0.9	1.0	0.9	-1.0	-0.8	0.3	0.0	0.1	-0.4	0.1
Condit. Reinf. active-inactive response ratio	2.3	3.6	5.9	2.4	2.3	2.3	2.0	2.3	-2.2	-1.8	1.5	-1.4	-1.3	-1.6	0.8
Condit. Reinf. active responses	0.1	0.1	0.6	0.3	-0.2	-0.2	0.2	-0.0	-0.1	-0.0	-0.4	0.7	0.8	0.4	-0.4
Condit. Reinf. inactive responses	1.6	2.4	3.8	-1.6	-2.0	-2.0	-1.3	-1.7	1.6	1.1	-1.3	1.7	1.6	1.5	-0.9
Condit. Reinf. lever presses	0.3	0.4	0.7	0.0	-0.8	-0.8	-0.5	-0.6	0.3	0.7	-0.8	0.9	0.8	0.5	-0.2
Condit. Reinf. lever reinforcers received	0.2	0.3	0.9	0.3	-0.3	-0.3	0.0	-0.2	0.1	0.3	-0.6	0.9	0.9	0.6	-0.6
Conditioned reinforcement - actives	0.3	1.3	2.1	-0.9	-1.4	-1.4	-1.3	-1.3	1.2	1.4	-1.1	1.0	0.9	0.9	-0.6
Conditioned reinforcement - inactives	0.1	0.2	0.5	-0.3	-0.5	-0.5	-0.7	-0.4	0.5	0.7	-0.4	0.3	0.1	0.3	-0.1
Conditioned locomotion	2.5	3.6	5.4	-1.0	-2.3	-2.3	-1.5	-2.3	1.6	2.2	-1.8	2.2	2.1	1.8	-1.3
Patch foraging indifference point 0 sec	0.0	0.1	0.3	-0.3	-0.3	-0.3	-0.2	-0.4	0.1	-0.1	-0.1	0.2	0.0	-0.0	0.5
Patch foraging indifference point AUC	0.0	0.1	0.2	0.3	-0.0	-0.0	0.2	0.1	-0.2	0.1	0.0	-0.3	-0.4	-0.4	0.5
Delay disc. indifference point, 0s delay	0.0	0.0	0.1	-0.0	0.0	0.0	0.3	-0.1	-0.1	-0.3	-0.0	0.2	0.2	-0.0	-0.0
Delay disc. indifference point, 16s delay	3.7	5.3	7.3	-2.1	-2.7	-2.7	-2.2	-2.5	2.4	2.2	-2.3	2.3	2.2	2.3	-1.2
Delay disc. indifference point, 2s delay	0.3	0.4	1.1	-0.7	-0.5	-0.5	-0.5	-0.7	0.7	0.5	-0.5	0.4	0.5	0.6	-1.0
Delay disc. indifference point, 24s delay	1.2	2.0	6.1	-2.5	-1.6	-1.6	-1.6	-1.6	1.8	0.6	-0.8	0.8	0.8	1.3	-0.6
Delay disc. indifference point, 4s delay	0.4	0.5	1.2	-1.1	-0.8	-0.8	-0.7	-1.0	0.5	-0.2	-0.2	0.6	0.4	0.2	0.8
Delay disc. indifference point, 8s delay	0.2	0.3	1.5	-1.2	-0.5	-0.5	-0.4	-0.4	0.6	-0.3	-0.0	0.1	0.0	0.2	0.4
Indifference point function ln k	0.2	0.5	1.1	-1.0	-0.6	-0.6	-0.7	-0.7	0.7	0.0	-0.7	0.9	0.9	0.8	-0.6
Indifference point function log k	0.2	0.5	1.1	-1.0	-0.6	-0.6	-0.7	-0.7	0.7	0.0	-0.7	0.9	0.9	0.8	-0.6
Patch foraging total patch changes 0 sec	0.0	0.1	0.3	-0.3	-0.4	-0.4	-0.3	-0.4	0.2	-0.1	-0.3	0.3	0.2	0.0	0.6
Patch foraging total patch changes 12 sec	0.2	0.2	0.8	0.2	0.3	0.3	0.5	0.0	-0.3	-0.2	0.2	-0.8	-0.9	-0.6	0.4
Patch foraging total patch changes 18 sec	0.3	0.6	0.9	-0.6	-0.9	-0.9	-0.9	-0.9	0.7	0.6	-0.9	0.9	0.8	0.7	-0.2
Patch foraging total patch changes 24 sec	0.0	0.1	0.3	0.4	0.3	0.3	0.2	0.3	-0.5	-0.4	0.3	-0.2	-0.2	-0.5	0.5
Patch foraging total patch changes 6 sec	0.3	0.5	0.8	0.7	0.6	0.6	0.7	0.5	-0.8	-0.5	0.4	-0.8	-0.9	-0.9	0.9
Patch foraging time to switch 0 sec	0.0	0.2	0.8	-0.4	0.0	0.0	-0.3	-0.6	0.5	0.3	-0.5	0.0	0.1	0.5	-0.9
Patch foraging water rate 0 sec	0.0	0.2	1.1	0.1	-0.5	-0.5	-0.3	-0.0	-0.1	0.2	0.2	0.5	0.3	-0.1	1.1
Patch foraging water rate 12 sec	0.0	0.1	0.2	-0.0	-0.3	-0.3	-0.2	-0.2	0.1	0.1	-0.2	0.5	0.4	0.1	0.4
Patch foraging water rate 18 sec	0.2	0.4	1.4	0.2	-0.6	-0.6	-0.4	-0.1	0.2	0.6	-0.5	1.2	1.1	0.6	-0.1
Patch foraging water rate 24 sec	0.5	0.8	2.5	0.3	-0.9	-0.9	-0.7	-0.7	0.3	0.8	-0.5	1.6	1.5	0.8	-0.4
Patch foraging water rate 6 sec	0.4	0.6	1.1	-0.8	-1.0	-1.0	-0.8	-0.6	0.7	0.6	-0.3	1.0	0.9	0.7	-0.3
Seeking ratio, delayed vs. immediate footshock	0.6	0.9	1.9	1.1	0.8	0.8	1.4	0.8	-1.1	-0.7	0.9	-0.5	-0.6	-1.0	1.3
Distance traveled before self-admin	0.0	0.1	0.4	0.1	-0.1	-0.1	-0.3	0.2	-0.3	-0.3	0.6	0.1	0.1	-0.2	0.3
Distance traveled after self-admin	0.8	1.4	3.0	-0.4	-1.7	-1.7	-1.4	-1.2	1.0	1.7	-1.0	1.2	1.0	0.8	-0.3
Extensor digitorum longus weight	0.1	0.3	1.5	1.2	0.4	0.4	0.1	0.3	-0.4	0.4	-0.8	0.3	0.4	0.3	-0.8
Bone: elastic displacement	0.8	1.0	1.6	1.2	1.0	1.0	1.1	0.9	-1.3	-0.9	1.1	-0.7	-0.8	-1.1	0.9
Bone: elastic work	8.7	11.4	15.9	3.8	3.7	3.7	4.0	3.6	-3.8	-3.3	3.3	-2.9	-2.8	-3.3	2.0
Bone: endosteal estimation	0.9	2.2	8.5	0.1	-0.7	-0.7	-1.0	-0.8	1.0	1.7	-1.8	1.5	1.8	1.8	-2.9
Bone: endosteal perimeter	0.2	0.5	1.5	1.2	0.8	0.8	0.8	0.7	-0.7	-0.3	0.1	0.1	0.4	0.1	-1.0
Epididymis fat weight	0.1	0.4	2.1	1.4	0.4	0.4	0.2	0.5	-0.4	0.7	-0.5	0.2	0.3	0.1	-0.9
Delta time in closed arm before/after self-admin	0.1	0.1	0.4	-0.1	0.3	0.3	-0.3	-0.2	0.1	-0.0	-0.7	-0.0	-0.0	0.1	-0.0
Delta time in open arm before/after self-admin	0.4	0.4	1.2	-1.0	-1.1	-1.1	-0.6	-0.7	0.7	0.5	-0.0	0.2	0.0	0.3	0.2
Diff in mean of infusions in LGA sessions	0.0	0.1	0.4	-0.1	-0.1	-0.1	0.3	-0.1	0.3	0.3	-0.2	0.1	0.2	0.3	-0.6
Delay discount exponential model param	1.8	2.5	5.3	2.3	1.9	1.9	1.6	2.0	-1.8	-0.9	1.2	-1.3	-1.2	-1.4	0.4
Extinction: sum of active levers before priming	0.4	0.6	1.5	-0.3	0.5	0.5	1.2	0.6	-0.3	-1.0	1.1	-1.0	-0.9	-0.5	0.3
Active lever presses in extinction session 6	0.3	0.3	1.7	-1.1	-0.2	-0.2	0.1	0.1	0.6	-0.2	0.5	-0.3	-0.1	0.4	-1.3
Bone: final force	2.1	3.4	11.8	3.4	2.1	2.1	2.3	2.3	-2.4	-1.2	1.1	-0.4	-0.1	-1.0	-0.4
Bone: final moment	3.1	5.0	14.8	3.8	2.6	2.6	2.8	2.8	-2.9	-1.6	1.6	-0.8	-0.6	-1.4	-0.1
Food consumed during 24 hour testing period	0.2	0.4	0.8	0.7	0.6	0.6	0.6	0.6	-0.7	-0.5	0.6	-0.6	-0.6	-0.7	0.9
Glucose	1.0	1.6	4.1	-1.7	0.8	0.8	0.7	0.9	0.1	-1.7	1.7	-2.0	-1.8	-0.7	-0.5
Heart weight	0.9	1.5	3.5	1.9	1.4	1.4	1.7	1.2	-1.4	-0.7	1.1	-1.0	-0.9	-1.0	0.1
Delay discount hyperbolic model param	1.5	1.9	4.4	2.1	1.7	1.7	1.4	1.8	-1.6	-0.8	1.0	-1.1	-1.0	-1.2	0.3
Intermittent access intake day 1-15 change	0.1	0.6	1.2	-1.0	-1.1	-1.1	-0.8	-1.0	0.8	0.7	-0.1	0.4	0.2	0.3	0.6
Intermittent access intake escalation	0.1	0.6	1.3	-1.1	-1.1	-1.1	-0.9	-1.1	0.8	0.5	-0.0	0.5	0.3	0.3	0.8
Intermittent access intake escalation 2	0.1	0.2	0.4	-0.6	-0.5	-0.5	-0.2	-0.5	0.3	0.3	0.6	0.0	-0.1	-0.1	0.6
Intermitt. access day 1 inactive lever presses	0.0	0.3	1.1	0.4	-0.4	-0.4	-0.8	-0.5	0.2	1.1	-0.5	0.7	0.6	0.4	0.2
Intermitt. access day 15 inactive lever presses	0.2	1.0	2.0	-0.1	-1.3	-1.3	-0.7	-1.2	0.6	1.1	-0.8	1.4	1.1	0.8	0.3
Intermitt. access escalation Index	0.1	0.2	1.4	0.0	0.2	0.2	-0.6	0.1	-0.2	-0.3	0.1	-0.1	-0.2	-0.4	1.2
Intermittent access day 1 total infusions	0.0	0.1	0.4	0.7	0.1	0.1	0.3	0.1	-0.2	0.4	-0.4	-0.0	-0.0	-0.0	-0.2
Intermittent access day 15 total infusions	0.1	0.1	0.3	-0.1	-0.6	-0.6	-0.2	-0.5	0.2	0.5	-0.3	0.3	0.2	0.1	0.5
Intermittent access terminal intake (last 3 days)	0.0	0.1	0.4	0.1	-0.3	-0.3	-0.0	-0.2	0.1	0.4	-0.1	0.0	-0.1	-0.1	0.6
Intermittent access total infusions	0.1	0.1	0.3	-0.0	-0.4	-0.4	-0.2	-0.5	0.2	0.5	-0.6	0.3	0.2	0.1	0.3
Intermittent access day 1 locomotion	0.7	1.2	1.9	-0.9	-1.3	-1.3	-1.1	-1.4	1.1	1.0	-1.3	1.1	1.1	1.0	-0.7
Intermittent access day 15 total locomotion	0.0	0.2	0.3	-0.1	-0.5	-0.5	-0.2	-0.6	0.3	0.5	-0.6	0.5	0.5	0.3	-0.2
Intermittent access total locomotion	0.7	0.8	1.5	-0.7	-1.1	-1.1	-0.9	-1.2	0.8	0.9	-1.0	0.9	0.9	0.7	-0.5
Intermittent access standard deviation	0.1	0.5	2.1	-1.5	-0.8	-0.8	-0.5	-0.8	1.0	0.3	-0.1	0.1	-0.0	0.5	-0.3
Left kidney weight	0.1	0.6	3.7	1.0	0.6	0.6	0.8	0.7	-0.5	-0.2	0.1	-0.1	0.2	0.2	-1.9
Right kidney weight	0.1	0.5	2.3	0.8	0.7	0.7	0.7	0.8	-0.5	-0.5	0.1	-0.2	0.0	0.0	-1.5
Cocaine induced anxiety	0.8	2.1	3.8	0.4	1.4	1.4	1.5	1.4	-1.2	-1.9	2.0	-1.7	-1.6	-1.4	0.5
Post-drug Anxiety	0.5	0.6	1.5	-0.6	0.5	0.5	0.7	0.3	-0.3	-1.2	1.2	-1.1	-1.0	-0.7	0.2
Baseline Anxiety	0.5	0.8	1.4	-1.2	-1.0	-1.0	-0.7	-1.1	1.1	0.8	-0.9	0.7	0.7	0.9	-0.4
Tail length	0.3	1.4	7.5	2.7	1.3	1.3	1.1	1.1	-1.6	0.1	0.4	-0.4	-0.4	-1.0	0.4
Length with tail	0.4	1.6	3.8	1.9	1.7	1.7	1.6	1.4	-1.4	-0.8	0.7	-1.0	-0.7	-0.9	-0.4
Length without tail	0.4	2.0	3.3	1.0	1.7	1.7	1.8	1.7	-1.2	-1.6	1.4	-1.5	-1.2	-1.0	-0.4
Times rat made contact with spout	3.1	3.5	5.0	1.5	1.9	1.9	1.9	1.7	-1.8	-1.4	1.9	-2.1	-2.2	-2.1	2.1
Lifetime Intake	0.1	0.2	0.4	-0.4	-0.5	-0.5	-0.4	-0.6	0.4	0.4	-0.5	0.1	0.1	0.1	0.4
Liver weight, left	0.5	0.9	2.2	-1.1	-0.9	-0.9	-0.8	-0.9	1.2	1.0	-0.8	0.4	0.5	1.0	-1.5
Liver weight, right	0.3	0.4	2.3	1.5	0.4	0.4	0.3	0.4	-0.5	0.5	-0.2	0.4	0.6	0.3	-1.1
Locomotor activity	0.7	1.1	1.5	-1.1	-1.1	-1.1	-1.0	-1.2	1.2	1.1	-0.9	0.8	0.7	1.1	-1.0
Locomotor testing distance	0.7	1.8	2.2	-1.3	-1.3	-1.3	-1.1	-1.5	1.5	1.1	-1.4	1.2	1.2	1.5	-1.4
Locomotor testing rearing	0.6	2.1	3.8	-1.6	-1.8	-1.8	-1.3	-1.9	1.6	1.5	-1.1	1.2	1.0	1.2	-0.4
Locomotion in novel chamber	0.1	0.1	0.7	0.2	0.2	0.2	0.3	0.2	-0.1	-0.3	-0.5	0.2	0.4	0.3	-0.8
Locomotion in novel chamber post-restriction	0.5	1.5	4.1	2.0	1.3	1.3	1.7	1.4	-1.4	-0.6	0.6	-0.8	-0.7	-1.0	0.6
Fecal boli incidents, locomotor time 1	0.3	0.7	1.5	-0.2	-0.8	-0.8	-0.3	-0.7	0.8	1.2	-0.9	0.8	0.8	0.9	-1.0
Change in fecal boli incidents, locomotor task	0.4	0.4	1.5	-1.2	0.0	0.0	-0.1	0.1	0.3	-0.6	0.6	-1.1	-1.1	-0.5	0.4
Time >=10cm from walls, locomotor time 1	0.4	0.6	1.4	-0.2	-0.7	-0.7	-0.9	-0.9	0.3	0.4	-0.8	1.2	1.0	0.6	0.6
Bouts of movement, locomotor time 1	0.0	0.1	0.1	-0.4	0.1	0.1	0.3	0.0	0.1	-0.2	0.2	-0.4	-0.4	-0.1	0.1
Total resting periods, locomotor time 1	0.1	0.1	0.3	-0.6	-0.0	-0.0	0.1	-0.1	0.2	-0.2	0.1	-0.3	-0.4	-0.0	0.2
Rest time, locomotor task time 1	0.0	0.1	0.4	-0.1	-0.1	-0.1	0.1	-0.2	0.2	0.3	0.0	-0.3	-0.3	0.0	-0.6
Distance moved, locomotor task time 1	0.1	0.3	0.8	-0.9	-0.6	-0.6	-0.8	-0.6	0.6	0.2	-0.4	0.4	0.4	0.5	0.4
Vertical activity count, locomotor time 1	0.0	0.2	0.4	0.0	-0.3	-0.3	-0.5	-0.3	0.2	0.3	-0.6	0.6	0.6	0.4	-0.1
Time >=10cm from walls, locomotor time 2	0.3	0.9	1.7	1.1	1.3	1.3	0.6	1.0	-1.2	-1.1	0.7	-0.5	-0.4	-0.9	0.7
Bouts of movement, locomotor time 2	0.1	0.2	0.6	-0.8	-0.0	-0.0	-0.7	-0.2	0.6	0.2	-0.4	0.0	0.1	0.5	-0.4
Total resting periods, locomotor time 2	0.1	0.3	0.7	-0.5	-0.2	-0.2	-0.8	-0.4	0.7	0.6	-0.8	0.4	0.5	0.8	-0.7
Rest time, locomotor task time 2	0.1	0.1	0.4	0.2	-0.3	-0.3	-0.1	-0.3	0.2	0.6	-0.6	0.2	0.2	0.4	-0.6
Distance moved, locomotor task time 2	0.1	0.1	0.4	-0.5	-0.0	-0.0	-0.4	-0.1	0.1	-0.3	0.1	-0.0	-0.1	-0.1	0.6
Vertical activity count, locomotor time 2	0.2	0.4	1.0	-0.1	-0.4	-0.4	-0.7	-0.5	0.4	0.6	-0.7	0.8	0.9	0.7	-1.0
Light reinforcement 1	0.3	1.6	3.0	1.7	1.5	1.5	1.4	1.4	-1.5	-0.9	0.6	-1.1	-1.1	-1.3	0.6
Light reinforcement 2	0.6	1.3	3.4	1.8	1.3	1.3	1.3	1.4	-1.3	-0.6	0.6	-0.8	-0.8	-1.0	0.2
Bone: marrow area	0.9	2.3	8.6	0.1	-0.7	-0.7	-1.0	-0.8	1.0	1.7	-1.8	1.5	1.8	1.8	-2.9
Bone: maximum diameter	0.5	1.0	3.3	1.8	1.1	1.1	1.3	1.0	-1.1	-0.6	0.3	0.2	0.5	-0.0	-1.2
Bone: maximum force	1.9	3.7	13.6	3.7	2.2	2.2	2.4	2.3	-2.5	-1.1	0.9	-0.3	-0.0	-0.8	-0.8
Bone: maximum moment	2.8	5.3	16.5	4.1	2.7	2.7	2.9	2.8	-2.9	-1.5	1.4	-0.8	-0.5	-1.3	-0.5
Mean time between licks in bursts	0.2	1.2	3.3	-1.8	-1.4	-1.4	-1.3	-1.3	1.4	0.6	-0.8	0.7	0.6	0.9	-0.3
Mean num. licks in bursts	0.5	1.2	1.8	0.8	1.3	1.3	1.2	1.0	-1.0	-0.9	1.1	-1.3	-1.2	-1.1	0.7
Cd content in liver	1.7	1.9	3.0	-0.9	-1.5	-1.5	-1.5	-1.2	1.4	1.7	-1.4	1.4	1.4	1.4	-1.1
Co content in liver	0.0	0.0	0.0	-0.0	0.2	0.2	0.1	0.0	-0.0	-0.1	0.2	-0.2	-0.2	-0.0	0.1
Cu content in liver	0.9	1.1	2.3	0.6	0.8	0.8	0.8	0.9	-1.0	-1.1	1.4	-1.0	-1.1	-1.2	1.5
Fe content in liver	1.6	2.0	2.5	-1.1	-1.4	-1.4	-1.5	-1.3	1.5	1.5	-1.5	1.4	1.4	1.6	-1.5
K content in liver	0.6	0.6	1.1	-0.3	-1.1	-1.1	-0.8	-0.8	0.5	0.9	-0.7	1.0	0.8	0.5	0.4
Mg content in liver	1.9	2.1	3.5	-1.0	-1.9	-1.9	-1.6	-1.8	1.3	1.7	-1.4	1.6	1.3	1.1	0.2
Mn content in liver	0.1	0.1	0.9	-0.2	-0.3	-0.3	-0.3	-0.3	0.0	0.1	0.1	0.1	-0.1	-0.2	1.0
Na content in liver	1.0	1.1	1.8	-1.1	-1.2	-1.2	-1.1	-1.3	1.1	0.9	-1.0	1.1	1.0	0.9	-0.3
Rb content in liver	0.2	0.2	0.9	0.9	-0.2	-0.2	0.1	-0.1	-0.5	0.3	-0.1	0.7	0.5	-0.1	0.6
Se content in liver	0.1	0.1	1.2	-0.1	-0.2	-0.2	-0.3	-0.1	-0.1	0.1	0.2	-0.1	-0.3	-0.4	1.1
Sr content in liver	1.2	1.1	1.7	0.1	0.9	0.9	0.9	0.7	-0.8	-1.3	1.1	-1.3	-1.3	-1.2	1.3
Zn content in liver	0.1	0.2	1.0	1.0	0.3	0.3	0.3	0.4	-0.4	0.4	-0.1	-0.1	-0.1	-0.2	-0.2
Bone: minimum diameter	1.5	2.9	7.1	2.7	2.1	2.1	2.1	2.1	-2.2	-1.5	1.2	-0.8	-0.6	-1.2	0.1
Time in familiar zone, hab. session 1	0.3	0.3	0.6	0.2	0.5	0.5	0.4	0.5	-0.4	-0.5	0.7	-0.8	-0.8	-0.6	0.4
Time in novel zone, hab. session 1	0.0	0.0	0.2	-0.1	-0.2	-0.2	0.0	-0.2	0.1	0.0	-0.2	0.1	0.1	-0.1	0.4
Total zone transitions, hab. session 1	0.2	0.2	0.4	-0.4	-0.6	-0.6	-0.4	-0.6	0.5	0.6	-0.5	0.5	0.4	0.4	-0.3
Total locomotion distance, hab. session 1	0.1	0.1	0.4	0.6	-0.1	-0.1	0.1	-0.1	-0.0	0.6	-0.5	0.4	0.4	0.3	-0.6
Locomotion velocity, hab. session 1	0.2	0.3	0.8	0.6	-0.3	-0.3	-0.1	-0.2	0.1	0.9	-0.7	0.7	0.6	0.5	-0.8
Time in familiar zone, hab. session 2	0.1	0.1	0.2	-0.5	-0.3	-0.3	-0.4	-0.3	0.4	0.3	-0.3	-0.1	-0.1	0.2	-0.1
Time in novel zone, hab. session 2	0.0	0.0	0.1	-0.1	-0.1	-0.1	-0.1	-0.2	0.0	-0.1	-0.0	0.3	0.3	0.1	-0.1
Total zone transitions, hab. session 2	0.3	0.3	0.8	0.3	-0.4	-0.4	-0.4	-0.4	0.3	0.8	-0.9	0.9	0.9	0.6	-0.3
Total locomotion distance, hab. session 2	0.2	0.3	1.2	1.1	0.1	0.1	0.2	0.0	-0.3	0.6	-0.8	0.6	0.5	0.2	-0.2
Locomotion velocity, hab. session 2	0.2	0.3	1.6	1.3	0.1	0.1	0.3	0.1	-0.4	0.6	-0.7	0.6	0.5	0.2	-0.2
Novel to familiar place preference ratio	3.0	4.0	5.1	2.0	2.3	2.3	2.2	2.1	-2.1	-2.0	1.9	-1.8	-1.7	-1.9	1.5
Novelty place preference	3.3	4.3	5.7	2.0	2.4	2.4	2.3	2.2	-2.2	-2.1	2.0	-1.9	-1.8	-2.0	1.5
Time in novel zone, NPP test	2.8	3.4	4.6	1.8	2.1	2.1	2.1	1.9	-2.0	-1.9	1.7	-1.7	-1.6	-1.8	1.4
Total zone transitions, NPP test	2.0	2.9	4.7	-0.7	-1.9	-1.9	-1.5	-1.6	1.5	1.9	-2.0	2.2	2.1	1.8	-1.1
Total locomotion distance, NPP test	1.5	2.1	4.0	-0.0	-1.4	-1.4	-1.1	-1.4	1.1	2.0	-1.9	1.8	1.8	1.5	-1.1
Locomotion velocity, NPP test	0.8	1.2	2.4	0.3	-1.0	-1.0	-0.7	-0.9	0.7	1.6	-1.5	1.4	1.4	1.1	-0.9
Intraocular pressure	0.4	0.7	1.5	0.6	-0.5	-0.5	-0.3	-0.5	0.3	1.2	-0.8	1.2	1.2	0.9	-1.1
Delta distance traveled before/after self-admin	0.8	0.9	1.6	-0.9	-1.3	-1.3	-0.8	-1.2	1.1	1.2	-1.0	0.6	0.5	0.7	-0.1
Delta ambulatory time before/after self-admin	0.6	1.0	1.6	-1.0	-1.2	-1.2	-1.0	-1.3	1.1	1.2	-1.1	0.5	0.5	0.7	-0.1
Parametrial fat weight	0.2	0.5	1.9	1.4	0.8	0.8	0.6	0.8	-0.8	0.1	-0.0	-0.7	-0.7	-0.6	0.3
Pavlov. Cond. lever latency	2.7	3.4	4.7	-1.3	-1.6	-1.6	-2.2	-2.0	1.7	1.8	-2.0	2.0	2.1	2.0	-1.8
Pavlov. Cond. magazine entry latency	2.4	3.1	4.1	1.4	1.4	1.4	2.0	1.9	-1.8	-1.8	2.0	-1.8	-1.8	-1.9	1.7
Pavlov. Cond. change in total contacts	1.0	1.1	2.1	0.5	0.7	0.7	1.3	1.1	-0.8	-1.0	1.3	-1.4	-1.4	-1.2	0.9
Pavlov. Cond. index score	3.0	3.8	5.7	1.9	1.7	1.7	2.4	2.2	-2.0	-1.7	1.9	-1.9	-2.0	-2.1	1.8
Pavlov. Cond. latency score	3.2	4.0	5.9	1.8	1.8	1.8	2.4	2.2	-2.0	-1.8	2.0	-2.0	-2.1	-2.1	1.8
Pavlov. Cond. lever contacts	1.0	1.2	2.1	0.9	0.8	0.8	1.4	1.2	-1.0	-0.8	1.1	-1.2	-1.2	-1.2	1.1
Pavlov. Cond. magazine entry number	3.4	4.4	5.8	-1.6	-1.9	-1.9	-2.4	-2.2	2.0	2.0	-2.4	2.2	2.3	2.2	-1.8
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.5	0.7	0.3	0.3	-0.1	0.0	-0.1	0.5	-0.5	0.2	0.3	0.1	-0.2
Pavlov. Cond. lever-magazine prob. diff.	2.7	3.3	4.7	1.7	1.6	1.6	2.2	2.0	-1.9	-1.7	1.9	-1.7	-1.8	-1.9	1.7
Pavlov. Cond. response bias	2.6	3.3	4.6	1.4	1.6	1.6	2.2	2.0	-1.7	-1.7	2.0	-2.0	-2.0	-1.9	1.5
Pavlov. Cond. lever latency	0.2	0.3	0.8	-0.9	0.2	0.2	0.1	0.2	0.2	-0.6	0.8	-0.7	-0.7	-0.4	0.6
Pavlov. Cond. magazine entry latency	2.7	3.9	5.0	-1.6	-2.0	-2.0	-2.0	-2.2	2.1	2.2	-2.2	1.7	1.7	2.0	-1.9
Pavlov. Cond. change in total contacts	0.5	1.2	2.1	-0.5	-1.0	-1.0	-0.9	-1.1	0.9	1.0	-1.3	1.3	1.3	1.3	-1.4
Pavlov. Cond. index score	0.9	1.4	2.3	-0.4	-1.1	-1.1	-1.0	-1.2	1.0	1.5	-1.5	1.2	1.2	1.2	-1.4
Pavlov. Cond. latency score	0.9	1.4	2.4	-0.4	-1.1	-1.1	-1.0	-1.2	1.0	1.5	-1.5	1.2	1.3	1.2	-1.4
Pavlov. Cond. lever contacts	0.2	0.3	0.8	0.8	-0.3	-0.3	-0.2	-0.3	-0.0	0.7	-0.9	0.8	0.8	0.5	-0.7
Pavlov. Cond. magazine entry number	2.5	3.2	4.4	1.6	1.7	1.7	1.9	2.1	-1.9	-1.9	2.1	-1.5	-1.5	-1.8	1.6
Pavlov. Cond. intertrial magazine entries	0.2	0.5	1.5	1.2	0.5	0.5	0.7	0.9	-0.9	-0.4	0.6	0.2	0.1	-0.5	0.8
Pavlov. Cond. lever-magazine prob. diff.	1.1	1.6	2.5	-0.7	-1.2	-1.2	-1.1	-1.4	1.2	1.5	-1.6	1.2	1.2	1.3	-1.5
Pavlov. Cond. response bias	0.6	0.8	1.5	-0.1	-0.8	-0.8	-0.8	-0.9	0.7	1.1	-1.2	0.9	0.9	0.9	-1.1
Time in closed arm before self-admin	0.0	0.0	0.1	-0.2	-0.1	-0.1	-0.0	0.2	-0.1	-0.4	0.4	-0.1	0.0	-0.2	0.1
Time in closed arm after self-admin	0.1	0.1	0.8	-0.9	-0.1	-0.1	-0.6	-0.3	0.4	-0.2	-0.1	-0.3	-0.2	-0.0	0.1
Time in open arm before self-admin	0.8	1.0	2.3	1.5	1.5	1.5	1.0	1.2	-1.1	-0.8	0.0	-0.5	-0.4	-0.6	0.1
Time in open arm after self-admin	0.2	0.2	0.3	-0.1	-0.5	-0.5	-0.0	-0.3	0.3	0.4	-0.3	0.5	0.5	0.5	-0.5
Bone: periosteal estimation	0.6	1.5	5.3	2.3	1.3	1.3	1.2	1.2	-1.2	-0.2	-0.1	0.4	0.8	0.3	-2.0
Bone: periosteal perimeter	2.6	5.2	8.9	3.0	2.8	2.8	3.0	2.7	-2.7	-2.2	1.9	-1.5	-1.2	-1.6	-0.1
Bone: post-yield work	0.2	0.3	1.2	0.1	-0.0	-0.0	-0.1	-0.1	0.2	0.1	-0.7	0.6	0.8	0.6	-1.1
Progressive ratio test 1 active lever presses	0.4	0.7	1.1	-0.8	-0.9	-0.9	-1.0	-1.0	0.8	0.8	-0.9	0.6	0.6	0.6	-0.1
Progressive ratio test 1 breakpoint	0.3	0.5	0.9	-0.7	-0.8	-0.8	-0.9	-0.9	0.8	0.8	-0.8	0.6	0.5	0.5	-0.1
Progressive ratio test 1 inactive lever presses	0.1	0.2	0.6	0.6	-0.3	-0.3	-0.5	-0.4	-0.0	0.8	-0.5	0.5	0.4	0.1	0.6
Progressive ratio test 2 active lever presses	0.2	0.3	0.7	-0.2	-0.6	-0.6	-0.4	-0.6	0.5	0.9	-0.8	0.5	0.5	0.5	-0.5
Progressive ratio test 2 breakpoint	0.3	0.4	0.8	-0.2	-0.7	-0.7	-0.5	-0.7	0.6	0.9	-0.8	0.6	0.5	0.6	-0.5
Progressive ratio test 2 inactive lever presses	0.0	0.0	0.0	-0.1	-0.1	-0.1	0.0	-0.1	0.2	0.2	-0.1	-0.0	-0.0	0.1	-0.1
Incentive Sensitization - Responses	0.0	0.1	0.4	0.6	0.1	0.1	0.2	0.2	-0.1	0.4	-0.2	-0.0	-0.0	-0.1	-0.2
Incentive Sensitization - Breakpoint	0.0	0.1	0.3	0.5	0.0	0.0	0.2	0.2	-0.1	0.4	-0.1	-0.0	-0.0	-0.0	-0.3
Sum of active levers in priming session hrs 5-6	0.7	0.6	1.6	0.3	0.7	0.7	1.1	0.8	-0.4	-0.5	0.8	-1.3	-1.2	-0.7	-0.0
Progressive ratio	0.5	1.4	3.1	-0.7	-1.0	-1.0	-0.8	-0.8	1.1	1.2	-1.0	1.3	1.4	1.5	-1.8
Food seeking constrained by brief footshock	0.2	0.2	1.0	-0.4	0.0	0.0	0.2	0.1	-0.1	-0.5	0.7	-0.6	-0.7	-0.5	1.0
Seeking ratio, punishment vs. effort	0.3	0.6	1.7	0.3	0.5	0.5	0.5	0.4	-0.8	-1.0	0.7	-0.7	-0.8	-1.0	1.3
Retroperitoneal fat weight	0.2	1.0	6.5	2.5	0.6	0.6	0.1	0.5	-0.9	1.1	-0.6	0.7	0.8	0.1	-0.7
Reaction time number correct	0.8	2.8	5.2	-0.6	-1.9	-1.9	-1.7	-1.5	1.3	1.7	-1.9	2.3	2.2	1.6	-0.8
Reaction time mean minus median	0.0	0.1	0.3	-0.5	-0.3	-0.3	-0.2	-0.4	0.5	0.4	0.0	-0.3	-0.3	0.1	-0.3
Reaction time mean minus median AUC	0.0	0.1	0.2	-0.2	-0.4	-0.4	0.0	-0.3	0.3	0.3	-0.0	0.1	0.0	0.2	-0.1
Reaction time num false alarms	0.1	0.2	0.4	0.4	0.6	0.6	0.5	0.6	-0.3	-0.4	0.3	-0.5	-0.3	-0.1	-0.4
Reaction time num false alarms AUC	0.0	0.0	0.3	-0.0	0.2	0.2	0.1	0.2	0.1	0.0	-0.1	-0.1	-0.0	0.2	-0.5
Reaction time trials correct on left	0.8	2.8	5.2	-0.6	-1.9	-1.9	-1.7	-1.5	1.3	1.7	-1.9	2.3	2.2	1.6	-0.8
Reaction time trials on left	0.9	3.0	5.5	-0.6	-1.9	-1.9	-1.7	-1.6	1.3	1.8	-2.0	2.3	2.2	1.7	-0.8
Reaction time mean	0.1	0.1	0.5	0.7	0.4	0.4	0.5	0.2	-0.4	0.1	0.1	-0.3	-0.4	-0.2	-0.0
Reaction time mean AUC	0.0	0.1	0.4	0.6	-0.1	-0.1	0.1	-0.1	-0.1	0.5	-0.4	0.3	0.2	0.2	-0.2
Median of all reaction times	0.1	0.2	0.8	0.9	0.5	0.5	0.6	0.3	-0.5	-0.0	0.1	-0.2	-0.2	-0.3	0.1
Reaction time omissions	0.1	0.2	0.5	-0.3	-0.5	-0.5	-0.5	-0.7	0.4	0.5	-0.4	0.5	0.4	0.4	0.3
Reaction time false alarm rate	0.7	0.9	1.9	0.3	1.2	1.2	0.9	1.0	-0.6	-1.0	1.0	-1.4	-1.2	-0.7	0.1
Reaction time premature initiation rate	0.1	0.1	0.7	-0.8	-0.2	-0.2	-0.3	-0.4	0.6	0.1	-0.2	-0.3	-0.3	0.2	-0.2
Reaction time premature initiations	0.5	1.4	1.8	-1.0	-1.3	-1.3	-1.2	-1.2	1.3	1.2	-1.4	1.1	1.1	1.2	-0.7
Std. dev. reaction times	0.1	0.3	0.6	-0.5	-0.7	-0.7	-0.4	-0.8	0.7	0.8	-0.5	0.3	0.2	0.5	-0.5
Reaction time trials completed	0.9	3.0	5.5	-0.6	-1.9	-1.9	-1.7	-1.6	1.3	1.8	-2.0	2.3	2.2	1.7	-0.8
Reaction time trials AUC	0.8	2.7	5.1	-0.5	-1.8	-1.8	-1.6	-1.5	1.2	1.7	-1.9	2.3	2.1	1.6	-0.7
Run reversals in cocaine runway, females	0.2	0.2	0.3	-0.3	-0.5	-0.5	-0.5	-0.4	0.4	0.4	-0.6	0.4	0.4	0.5	-0.4
Run reversals in cocaine runway, males	1.2	1.3	1.6	1.2	1.3	1.3	1.2	1.1	-1.2	-0.8	1.1	-1.3	-1.2	-1.2	0.7
Latency to leave start box in cocaine runway	0.7	1.0	2.2	-0.3	-1.0	-1.0	-0.9	-0.8	0.9	1.5	-1.0	0.9	0.9	1.0	-1.4
Latency to leave start box in cocaine runway, F	2.0	2.5	4.5	-0.2	-1.6	-1.6	-1.4	-1.3	1.2	2.1	-1.8	1.8	1.8	1.6	-1.7
Latency to leave start box in cocaine runway, M	0.2	0.2	0.5	-0.1	0.5	0.5	0.3	0.4	-0.1	-0.2	0.6	-0.7	-0.7	-0.3	-0.2
Std. dev. time between licks in bursts	1.5	2.8	4.9	-0.6	-1.8	-1.8	-1.6	-1.7	1.2	1.7	-1.9	2.2	2.1	1.6	-0.7
Total sessions with >9 infusions	0.3	0.4	0.7	-0.9	-0.7	-0.7	-0.7	-0.7	0.8	0.5	-0.8	0.4	0.4	0.6	-0.2
Short access day 1 total inactive lever presses	0.3	0.7	1.6	-0.2	-0.6	-0.6	-0.7	-0.7	0.7	1.0	-1.2	0.7	0.8	0.9	-1.2
Short access day 10 total inactive lever presses	0.0	0.2	1.2	1.1	0.3	0.3	0.2	0.3	-0.6	0.0	0.1	0.2	0.1	-0.3	0.6
Short access day 1 total infusions	0.2	0.4	2.0	-1.4	-0.6	-0.6	-0.8	-0.6	0.9	0.1	-0.5	0.1	0.1	0.5	0.1
Short access day 10 total infusions	0.1	0.1	0.3	0.0	-0.3	-0.3	-0.2	-0.4	0.2	0.5	-0.3	0.0	-0.1	-0.0	0.6
Short access total infusions	0.2	0.3	0.8	-0.9	-0.6	-0.6	-0.7	-0.7	0.7	0.4	-0.5	0.1	-0.0	0.2	0.5
Short access day 1 locomotion	0.1	0.1	0.9	-0.9	-0.3	-0.3	0.0	-0.2	0.4	-0.3	0.1	-0.1	-0.1	0.1	0.3
Short access day 10 total locomotion	0.0	0.2	0.5	-0.6	0.0	0.0	0.1	-0.1	0.0	-0.5	0.5	-0.7	-0.7	-0.5	0.7
Short access total locomotion	0.1	0.1	0.5	-0.7	-0.1	-0.1	0.0	-0.1	0.2	-0.3	0.1	-0.5	-0.4	-0.2	0.4
One hour access (0.3 mA shock)	0.0	0.1	0.3	0.4	-0.2	-0.2	-0.0	-0.1	0.0	0.6	-0.3	0.0	-0.1	-0.1	0.1
Compulsive drug intake	0.2	0.3	1.1	1.0	0.6	0.6	-0.3	0.6	-0.7	-0.1	0.1	-0.1	-0.2	-0.4	0.5
One hour access (shock baseline)	0.0	0.1	0.3	0.1	-0.4	-0.4	0.3	-0.3	0.2	0.6	-0.5	0.1	0.0	0.1	-0.0
Social response proportion	1.0	1.3	1.7	-1.3	-1.2	-1.2	-1.2	-1.1	1.2	0.7	-1.0	1.2	1.2	1.2	-0.9
Social responses	0.2	0.3	0.6	-0.8	-0.6	-0.6	-0.6	-0.5	0.5	-0.1	-0.6	0.6	0.6	0.5	-0.1
Social time	0.0	0.1	0.1	-0.1	-0.0	-0.0	-0.1	0.0	0.1	-0.0	-0.3	0.3	0.4	0.3	-0.4
Soleus weight	1.1	3.3	5.4	2.3	2.0	2.0	1.7	1.9	-2.2	-1.5	1.2	-1.5	-1.5	-1.9	1.8
Bone: stiffness	0.4	0.7	3.0	1.3	0.3	0.3	0.4	0.4	-0.3	0.4	-0.5	0.8	1.0	0.7	-1.7
Tibialis anterior weight	0.1	0.4	1.1	1.0	0.8	0.8	0.5	0.7	-0.7	-0.2	-0.0	-0.5	-0.5	-0.5	-0.0
Time to tail flick, vehicle, before self-admin	0.6	0.8	1.4	-0.8	-1.2	-1.2	-0.7	-1.2	0.8	0.8	-0.5	1.0	0.8	0.6	-0.1
Time to tail flick, vehicle, after self-admin	0.2	0.4	1.7	-0.6	-0.4	-0.4	-0.5	-0.6	0.7	0.4	-0.6	0.4	0.5	0.7	-1.3
Time to tail flick, test, before self-admin	1.3	1.5	2.9	-1.2	-1.6	-1.6	-1.7	-1.7	1.2	1.4	-0.9	0.9	0.8	0.8	-0.3
Time to tail flick, test, after self-admin	1.6	1.7	4.5	-2.1	-1.6	-1.6	-1.9	-1.7	1.5	0.7	-0.7	0.7	0.6	0.8	-0.2
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.3	0.5	0.4	0.4	-0.1	0.4	-0.2	0.1	-0.2	-0.3	-0.2	-0.1	-0.5
Delta time to tail flick, test, before/after SA	0.4	0.5	1.2	-0.1	0.8	0.8	0.9	0.8	-0.3	-1.1	0.7	-0.8	-0.7	-0.3	-0.1
Tibia length	6.8	18.8	39.5	6.3	5.1	5.1	5.1	5.0	-5.4	-3.8	3.5	-2.7	-2.4	-3.6	1.6
Ambulatory time before self-admin	0.1	0.2	0.8	0.5	0.1	0.1	0.0	0.5	-0.7	-0.5	0.9	0.0	-0.1	-0.5	0.7
Ambulatory time after self-admin	0.2	0.3	0.9	-0.2	-0.9	-0.9	-0.7	-0.5	0.4	0.8	-0.3	0.6	0.5	0.3	0.1
Bone: tissue strength	0.4	0.4	2.3	1.5	0.5	0.5	0.3	0.4	-0.7	0.1	-0.3	0.7	0.8	0.3	-0.9
Total heroin consumption	0.2	0.2	1.7	-0.1	0.2	0.2	0.3	0.1	0.1	-0.1	0.1	-0.0	0.3	0.5	-1.3
Bone: trabecular number	0.2	0.4	0.6	0.4	0.6	0.6	0.8	0.7	-0.6	-0.7	0.6	-0.7	-0.7	-0.7	0.7
Bone: trabecular spacing	2.4	3.4	5.7	-0.5	-1.6	-1.6	-1.9	-1.7	1.5	2.1	-2.2	2.4	2.4	2.0	-1.6
Bone: trabecular thickness	3.5	4.9	6.7	1.5	2.3	2.3	2.6	2.3	-2.1	-2.4	2.2	-2.4	-2.4	-2.2	1.4
Bone: trabecular tissue density	1.2	2.1	2.7	-1.5	-1.4	-1.4	-1.6	-1.6	1.6	1.3	-1.2	1.4	1.4	1.5	-1.4
Water consumed over 24 hours	0.8	1.6	2.3	0.5	1.2	1.2	1.1	1.1	-1.1	-1.4	1.5	-1.5	-1.5	-1.3	1.4
Number of responses in last shaping day	0.1	0.2	0.7	-0.8	-0.6	-0.6	-0.2	-0.4	0.5	0.2	-0.2	0.0	-0.0	0.2	0.1