Hub : Genes

Zfp950l11

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Zfp950l11 0.02 0.01 6.6e-04 0.01 0.02 0.01 0.01 1.6e-02 1.5e-03 4.5e-02 8.5e-03
2 NAcc mRNA stability Zfp950l11 0.07 0.03 4.8e-08 0.05 0.04 0.04 0.04 8.5e-08 2.8e-07 1.5e-06 5.7e-07
3 BLA gene expression Zfp950l11 0.09 0.05 3.5e-04 0.09 0.06 0.07 0.07 2.2e-05 2.4e-04 1.1e-04 1.2e-04
4 LHb mRNA stability Zfp950l11 0.31 0.13 3.4e-04 0.17 0.15 0.13 0.13 9.6e-05 1.9e-04 5.9e-04 6.2e-04
5 OFC mRNA stability Zfp950l11 0.27 0.16 5.8e-03 0.08 0.07 0 0.04 5.9e-03 1.1e-02 2.5e-01 3.5e-02
6 Brain mRNA stability Zfp950l11 0.09 0.04 3.5e-10 0.11 0.11 0.08 0.11 3.8e-10 2.5e-10 3.1e-08 3.2e-10
7 LHb gene expression Zfp950l11 0.28 0.14 2.2e-03 0.06 0.08 0.06 0.06 1.4e-02 7.3e-03 1.5e-02 1.3e-02
8 Brain gene expression Zfp950l11 0.1 0.04 9.9e-09 0.09 0.09 0.1 0.09 2.1e-08 7.5e-09 3.6e-09 4.5e-09
9 NAcc gene expression Zfp950l11 0.03 0.02 1.1e-03 0.01 0.01 0.01 0.01 4.1e-03 2.2e-03 1.4e-02 5.2e-03
10 pVTA mRNA stability Zfp950l11 0.05 0.03 4.9e-03 0.01 0.03 0.02 0.01 2.8e-02 3.3e-03 1.6e-02 2.3e-02
11 PL gene expression Zfp950l11 0.05 0.03 3.4e-05 0.03 0.04 0.02 0.03 1.5e-04 6.2e-05 5.3e-03 1.6e-04
12 pVTA gene expression Zfp950l11 0.09 0.05 1.4e-03 0.01 0.02 0.03 0.01 2.2e-02 6.3e-03 1.0e-03 4.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.10.10.40.6-0.4-0.4-0.5-0.4-0.5-0.4-0.20.00.1-0.2-0.2
Area under the delay curve2.02.33.9-2.01.81.81.51.91.71.01.31.41.31.40.5
BMI with tail0.30.92.61.6-1.0-1.0-1.2-1.3-1.0-0.5-0.2-0.20.1-0.21.2
BMI without tail0.30.95.82.4-0.7-0.7-0.9-0.9-1.20.40.10.40.4-0.30.4
Body weight0.72.910.93.3-2.0-2.0-2.2-2.0-2.0-0.6-0.5-0.6-0.2-0.71.3
Weight adjusted by age1.93.05.92.4-2.2-2.2-1.9-2.2-2.0-1.5-1.2-1.1-0.9-1.3-0.2
Bone surface0.10.20.60.8-0.5-0.5-0.4-0.4-0.4-0.1-0.00.10.2-0.00.5
Bone volume0.10.20.70.8-0.6-0.6-0.6-0.6-0.6-0.3-0.1-0.1-0.0-0.20.2
Breakpoint value in progressive ratio session0.30.43.0-0.40.20.2-0.10.20.60.50.20.10.30.81.7
Number of licking bursts0.00.10.20.20.40.40.20.20.00.30.20.30.20.1-0.5
Context. condit. distance diff. score0.40.51.00.40.50.50.70.50.31.01.00.90.90.70.4
Locomotion velocity, session 10.90.92.2-0.6-0.8-0.8-0.6-0.7-0.4-1.4-1.1-1.5-1.4-1.0-0.8
Locomotion distance, session 11.11.31.7-1.21.11.11.11.11.20.81.21.21.31.31.3
Locomotion velocity, session 22.12.45.6-2.41.81.81.71.81.91.01.21.11.11.41.1
Locomotion distance, session 21.01.42.3-0.61.21.21.11.21.01.11.31.51.51.20.8
Locomotion velocity, session 31.01.23.9-2.01.31.31.41.21.30.30.40.70.70.80.3
Locomotion distance, session 32.73.06.6-2.62.02.01.91.92.01.01.21.41.31.61.2
Stereotopy head waving bouts, day 30.20.20.40.0-0.5-0.5-0.2-0.6-0.3-0.7-0.5-0.5-0.4-0.30.1
Stereotopy head waving duration, day 30.00.00.20.1-0.2-0.20.0-0.3-0.1-0.2-0.1-0.10.00.10.4
Locomotion velocity, session 71.01.11.7-1.21.31.31.01.01.20.90.91.01.01.00.8
Locomotion distance, session 73.74.76.6-2.52.62.62.62.22.41.91.91.91.82.01.3
Stereotopy head waving bouts, day 70.40.41.51.2-0.9-0.9-0.5-0.8-0.7-0.2-0.1-0.2-0.1-0.10.7
Stereotopy head waving duration, day 70.30.31.21.1-0.8-0.8-0.4-0.8-0.7-0.4-0.2-0.2-0.1-0.20.3
Locomotion velocity, session 80.91.02.0-0.81.11.11.01.00.80.50.91.41.41.00.6
Locomotion distance, session 82.33.46.3-0.11.61.61.71.61.32.22.32.52.51.91.5
Degree of sensitization distance0.10.10.40.6-0.2-0.2-0.0-0.2-0.40.2-0.0-0.1-0.2-0.3-0.6
Degree of sensitization stereotypy0.20.20.90.9-0.5-0.5-0.2-0.5-0.40.10.20.10.20.10.6
Conditioned locomotion0.80.94.12.0-1.1-1.1-0.9-0.9-1.3-0.2-0.2-0.1-0.1-0.6-0.6
Cocaine response after cond. corrected0.10.10.3-0.5-0.0-0.0-0.1-0.00.0-0.5-0.3-0.5-0.5-0.3-0.4
Cocaine response after cond. not corrected0.20.31.2-1.10.60.60.50.60.70.10.20.10.00.30.1
Cocaine response before conditioning2.22.63.1-1.31.81.81.61.61.61.71.51.71.61.71.3
Saline control response0.50.73.80.9-0.4-0.4-0.4-0.3-0.9-0.5-0.5-0.2-0.4-1.0-1.9
Bone: connectivity density0.10.20.7-0.10.50.50.40.40.20.30.50.80.80.40.0
Bone: cortical apparent density0.81.14.9-2.21.21.21.41.31.30.20.30.30.20.5-0.1
Bone: cortical area2.74.212.13.5-2.4-2.4-2.7-2.4-2.6-1.6-1.4-0.5-0.3-1.10.5
Bone: cortical porosity1.71.92.91.3-1.5-1.5-1.7-1.7-1.2-1.0-1.5-1.6-1.5-1.10.3
Bone: cortical porosity1.92.13.51.5-1.5-1.5-1.9-1.7-1.4-1.0-1.6-1.5-1.4-1.2-0.1
Bone: cortical thickness4.47.212.03.5-3.0-3.0-3.3-3.1-3.3-2.8-2.5-1.7-1.5-2.2-1.1
Bone: cortical thickness2.32.83.91.8-1.8-1.8-2.0-1.9-1.9-1.7-1.7-1.3-1.2-1.5-1.1
Bone: cortical tissue density0.81.15.3-2.31.11.11.41.21.30.10.30.10.00.4-0.3
Condit. Reinf. active minus inactive responses1.11.33.11.8-1.4-1.4-1.3-1.1-1.5-0.9-0.7-0.7-0.6-1.0-0.5
Condit. Reinf. active-inactive response ratio0.60.61.11.0-0.9-0.9-0.9-0.8-1.0-1.0-0.7-0.2-0.1-0.6-0.4
Condit. Reinf. active responses1.41.85.52.3-1.5-1.5-1.6-1.3-1.7-0.7-0.6-0.8-0.8-1.2-0.7
Condit. Reinf. inactive responses0.30.41.31.1-0.6-0.6-0.7-0.5-0.70.1-0.0-0.5-0.6-0.6-0.4
Incentive salience index mean0.50.62.21.5-0.9-0.9-1.1-0.7-1.0-0.4-0.3-0.3-0.2-0.6-0.2
Condit. Reinf. lever presses0.20.30.8-0.10.50.50.30.60.50.90.90.50.50.60.6
Condit. Reinf. active minus inactive responses0.40.61.71.3-0.9-0.9-1.0-0.9-1.0-0.8-0.30.00.1-0.4-0.1
Condit. Reinf. active-inactive response ratio3.13.65.92.4-2.3-2.3-2.0-2.3-2.2-1.8-1.5-1.4-1.3-1.6-0.8
Condit. Reinf. active responses0.10.10.60.30.20.2-0.20.0-0.1-0.00.40.70.80.40.4
Condit. Reinf. inactive responses1.82.43.8-1.62.02.01.31.71.61.11.31.71.61.50.9
Condit. Reinf. lever presses0.30.40.70.00.80.80.50.60.30.70.80.90.80.50.2
Condit. Reinf. lever reinforcers received0.20.30.90.30.30.3-0.00.20.10.30.60.90.90.60.6
Conditioned reinforcement - actives0.81.32.1-0.91.41.41.31.31.21.41.11.00.90.90.6
Conditioned reinforcement - inactives0.10.20.5-0.30.50.50.70.40.50.70.40.30.10.30.1
Conditioned locomotion2.83.65.4-1.02.32.31.52.31.62.21.82.22.11.81.3
Patch foraging indifference point 0 sec0.00.10.3-0.30.30.30.20.40.1-0.10.10.20.0-0.0-0.5
Patch foraging indifference point AUC0.10.10.20.30.00.0-0.2-0.1-0.20.1-0.0-0.3-0.4-0.4-0.5
Delay disc. indifference point, 0s delay0.00.00.1-0.0-0.0-0.0-0.30.1-0.1-0.30.00.20.2-0.00.0
Delay disc. indifference point, 16s delay4.85.37.3-2.12.72.72.22.52.42.22.32.32.22.31.2
Delay disc. indifference point, 2s delay0.30.41.1-0.70.50.50.50.70.70.50.50.40.50.61.0
Delay disc. indifference point, 24s delay1.82.06.1-2.51.61.61.61.61.80.60.80.80.81.30.6
Delay disc. indifference point, 4s delay0.40.51.2-1.10.80.80.71.00.5-0.20.20.60.40.2-0.8
Delay disc. indifference point, 8s delay0.20.31.5-1.20.50.50.40.40.6-0.30.00.10.00.2-0.4
Indifference point function ln k0.30.51.1-1.00.60.60.70.70.70.00.70.90.90.80.6
Indifference point function log k0.30.51.1-1.00.60.60.70.70.70.00.70.90.90.80.6
Patch foraging total patch changes 0 sec0.10.10.3-0.30.40.40.30.40.2-0.10.30.30.20.0-0.6
Patch foraging total patch changes 12 sec0.20.20.80.2-0.3-0.3-0.5-0.0-0.3-0.2-0.2-0.8-0.9-0.6-0.4
Patch foraging total patch changes 18 sec0.40.60.9-0.60.90.90.90.90.70.60.90.90.80.70.2
Patch foraging total patch changes 24 sec0.10.10.30.4-0.3-0.3-0.2-0.3-0.5-0.4-0.3-0.2-0.2-0.5-0.5
Patch foraging total patch changes 6 sec0.30.50.80.7-0.6-0.6-0.7-0.5-0.8-0.5-0.4-0.8-0.9-0.9-0.9
Patch foraging time to switch 0 sec0.10.20.8-0.4-0.0-0.00.30.60.50.30.50.00.10.50.9
Patch foraging water rate 0 sec0.10.21.10.10.50.50.30.0-0.10.2-0.20.50.3-0.1-1.1
Patch foraging water rate 12 sec0.00.10.2-0.00.30.30.20.20.10.10.20.50.40.1-0.4
Patch foraging water rate 18 sec0.20.41.40.20.60.60.40.10.20.60.51.21.10.60.1
Patch foraging water rate 24 sec0.50.82.50.30.90.90.70.70.30.80.51.61.50.80.4
Patch foraging water rate 6 sec0.40.61.1-0.81.01.00.80.60.70.60.31.00.90.70.3
Seeking ratio, delayed vs. immediate footshock0.70.91.91.1-0.8-0.8-1.4-0.8-1.1-0.7-0.9-0.5-0.6-1.0-1.3
Distance traveled before self-admin0.10.10.40.10.10.10.3-0.2-0.3-0.3-0.60.10.1-0.2-0.3
Distance traveled after self-admin1.21.43.0-0.41.71.71.41.21.01.71.01.21.00.80.3
Extensor digitorum longus weight0.10.31.51.2-0.4-0.4-0.1-0.3-0.40.40.80.30.40.30.8
Bone: elastic displacement0.91.01.61.2-1.0-1.0-1.1-0.9-1.3-0.9-1.1-0.7-0.8-1.1-0.9
Bone: elastic work8.711.415.93.8-3.7-3.7-4.0-3.6-3.8-3.3-3.3-2.9-2.8-3.3-2.0
Bone: endosteal estimation1.02.28.50.10.70.71.00.81.01.71.81.51.81.82.9
Bone: endosteal perimeter0.20.51.51.2-0.8-0.8-0.8-0.7-0.7-0.3-0.10.10.40.11.0
Epididymis fat weight0.10.42.11.4-0.4-0.4-0.2-0.5-0.40.70.50.20.30.10.9
Delta time in closed arm before/after self-admin0.10.10.4-0.1-0.3-0.30.30.20.1-0.00.7-0.0-0.00.10.0
Delta time in open arm before/after self-admin0.40.41.2-1.01.11.10.60.70.70.50.00.20.00.3-0.2
Diff in mean of infusions in LGA sessions0.10.10.4-0.10.10.1-0.30.10.30.30.20.10.20.30.6
Delay discount exponential model param2.22.55.32.3-1.9-1.9-1.6-2.0-1.8-0.9-1.2-1.3-1.2-1.4-0.4
Extinction: sum of active levers before priming0.50.61.5-0.3-0.5-0.5-1.2-0.6-0.3-1.0-1.1-1.0-0.9-0.5-0.3
Active lever presses in extinction session 60.30.31.7-1.10.20.2-0.1-0.10.6-0.2-0.5-0.3-0.10.41.3
Bone: final force2.13.411.83.4-2.1-2.1-2.3-2.3-2.4-1.2-1.1-0.4-0.1-1.00.4
Bone: final moment3.15.014.83.8-2.6-2.6-2.8-2.8-2.9-1.6-1.6-0.8-0.6-1.40.1
Food consumed during 24 hour testing period0.30.40.80.7-0.6-0.6-0.6-0.6-0.7-0.5-0.6-0.6-0.6-0.7-0.9
Glucose1.01.64.1-1.7-0.8-0.8-0.7-0.90.1-1.7-1.7-2.0-1.8-0.70.5
Heart weight1.01.53.51.9-1.4-1.4-1.7-1.2-1.4-0.7-1.1-1.0-0.9-1.0-0.1
Delay discount hyperbolic model param1.71.94.42.1-1.7-1.7-1.4-1.8-1.6-0.8-1.0-1.1-1.0-1.2-0.3
Intermittent access intake day 1-15 change0.30.61.2-1.01.11.10.81.00.80.70.10.40.20.3-0.6
Intermittent access intake escalation0.30.61.3-1.11.11.10.91.10.80.50.00.50.30.3-0.8
Intermittent access intake escalation 20.20.20.4-0.60.50.50.20.50.30.3-0.60.0-0.1-0.1-0.6
Intermitt. access day 1 inactive lever presses0.10.31.10.40.40.40.80.50.21.10.50.70.60.4-0.2
Intermitt. access day 15 inactive lever presses0.51.02.0-0.11.31.30.71.20.61.10.81.41.10.8-0.3
Intermitt. access escalation Index0.10.21.40.0-0.2-0.20.6-0.1-0.2-0.3-0.1-0.1-0.2-0.4-1.2
Intermittent access day 1 total infusions0.10.10.40.7-0.1-0.1-0.3-0.1-0.20.40.4-0.0-0.0-0.00.2
Intermittent access day 15 total infusions0.10.10.3-0.10.60.60.20.50.20.50.30.30.20.1-0.5
Intermittent access terminal intake (last 3 days)0.00.10.40.10.30.30.00.20.10.40.10.0-0.1-0.1-0.6
Intermittent access total infusions0.10.10.3-0.00.40.40.20.50.20.50.60.30.20.1-0.3
Intermittent access day 1 locomotion1.01.21.9-0.91.31.31.11.41.11.01.31.11.11.00.7
Intermittent access day 15 total locomotion0.10.20.3-0.10.50.50.20.60.30.50.60.50.50.30.2
Intermittent access total locomotion0.70.81.5-0.71.11.10.91.20.80.91.00.90.90.70.5
Intermittent access standard deviation0.20.52.1-1.50.80.80.50.81.00.30.10.1-0.00.50.3
Left kidney weight0.10.63.71.0-0.6-0.6-0.8-0.7-0.5-0.2-0.1-0.10.20.21.9
Right kidney weight0.10.52.30.8-0.7-0.7-0.7-0.8-0.5-0.5-0.1-0.20.00.01.5
Cocaine induced anxiety1.52.13.80.4-1.4-1.4-1.5-1.4-1.2-1.9-2.0-1.7-1.6-1.4-0.5
Post-drug Anxiety0.60.61.5-0.6-0.5-0.5-0.7-0.3-0.3-1.2-1.2-1.1-1.0-0.7-0.2
Baseline Anxiety0.70.81.4-1.21.01.00.71.11.10.80.90.70.70.90.4
Tail length0.41.47.52.7-1.3-1.3-1.1-1.1-1.60.1-0.4-0.4-0.4-1.0-0.4
Length with tail0.41.63.81.9-1.7-1.7-1.6-1.4-1.4-0.8-0.7-1.0-0.7-0.90.4
Length without tail0.62.03.31.0-1.7-1.7-1.8-1.7-1.2-1.6-1.4-1.5-1.2-1.00.4
Times rat made contact with spout3.13.55.01.5-1.9-1.9-1.9-1.7-1.8-1.4-1.9-2.1-2.2-2.1-2.1
Lifetime Intake0.10.20.4-0.40.50.50.40.60.40.40.50.10.10.1-0.4
Liver weight, left0.60.92.2-1.10.90.90.80.91.21.00.80.40.51.01.5
Liver weight, right0.30.42.31.5-0.4-0.4-0.3-0.4-0.50.50.20.40.60.31.1
Locomotor activity0.71.11.5-1.11.11.11.01.21.21.10.90.80.71.11.0
Locomotor testing distance1.01.82.2-1.31.31.31.11.51.51.11.41.21.21.51.4
Locomotor testing rearing1.02.13.8-1.61.81.81.31.91.61.51.11.21.01.20.4
Locomotion in novel chamber0.10.10.70.2-0.2-0.2-0.3-0.2-0.1-0.30.50.20.40.30.8
Locomotion in novel chamber post-restriction0.91.54.12.0-1.3-1.3-1.7-1.4-1.4-0.6-0.6-0.8-0.7-1.0-0.6
Fecal boli incidents, locomotor time 10.50.71.5-0.20.80.80.30.70.81.20.90.80.80.91.0
Change in fecal boli incidents, locomotor task0.40.41.5-1.2-0.0-0.00.1-0.10.3-0.6-0.6-1.1-1.1-0.5-0.4
Time >=10cm from walls, locomotor time 10.50.61.4-0.20.70.70.90.90.30.40.81.21.00.6-0.6
Bouts of movement, locomotor time 10.00.10.1-0.4-0.1-0.1-0.3-0.00.1-0.2-0.2-0.4-0.4-0.1-0.1
Total resting periods, locomotor time 10.10.10.3-0.60.00.0-0.10.10.2-0.2-0.1-0.3-0.4-0.0-0.2
Rest time, locomotor task time 10.10.10.4-0.10.10.1-0.10.20.20.3-0.0-0.3-0.30.00.6
Distance moved, locomotor task time 10.20.30.8-0.90.60.60.80.60.60.20.40.40.40.5-0.4
Vertical activity count, locomotor time 10.10.20.40.00.30.30.50.30.20.30.60.60.60.40.1
Time >=10cm from walls, locomotor time 20.60.91.71.1-1.3-1.3-0.6-1.0-1.2-1.1-0.7-0.5-0.4-0.9-0.7
Bouts of movement, locomotor time 20.10.20.6-0.80.00.00.70.20.60.20.40.00.10.50.4
Total resting periods, locomotor time 20.20.30.7-0.50.20.20.80.40.70.60.80.40.50.80.7
Rest time, locomotor task time 20.10.10.40.20.30.30.10.30.20.60.60.20.20.40.6
Distance moved, locomotor task time 20.10.10.4-0.50.00.00.40.10.1-0.3-0.1-0.0-0.1-0.1-0.6
Vertical activity count, locomotor time 20.30.41.0-0.10.40.40.70.50.40.60.70.80.90.71.0
Light reinforcement 10.61.63.01.7-1.5-1.5-1.4-1.4-1.5-0.9-0.6-1.1-1.1-1.3-0.6
Light reinforcement 20.81.33.41.8-1.3-1.3-1.3-1.4-1.3-0.6-0.6-0.8-0.8-1.0-0.2
Bone: marrow area1.02.38.60.10.70.71.00.81.01.71.81.51.81.82.9
Bone: maximum diameter0.51.03.31.8-1.1-1.1-1.3-1.0-1.1-0.6-0.30.20.5-0.01.2
Bone: maximum force2.13.713.63.7-2.2-2.2-2.4-2.3-2.5-1.1-0.9-0.3-0.0-0.80.8
Bone: maximum moment3.05.316.54.1-2.7-2.7-2.9-2.8-2.9-1.5-1.4-0.8-0.5-1.30.5
Mean time between licks in bursts0.51.23.3-1.81.41.41.31.31.40.60.80.70.60.90.3
Mean num. licks in bursts0.81.21.80.8-1.3-1.3-1.2-1.0-1.0-0.9-1.1-1.3-1.2-1.1-0.7
Cd content in liver1.71.93.0-0.91.51.51.51.21.41.71.41.41.41.41.1
Co content in liver0.00.00.0-0.0-0.2-0.2-0.1-0.0-0.0-0.1-0.2-0.2-0.2-0.0-0.1
Cu content in liver0.91.12.30.6-0.8-0.8-0.8-0.9-1.0-1.1-1.4-1.0-1.1-1.2-1.5
Fe content in liver1.72.02.5-1.11.41.41.51.31.51.51.51.41.41.61.5
K content in liver0.60.61.1-0.31.11.10.80.80.50.90.71.00.80.5-0.4
Mg content in liver2.12.13.5-1.01.91.91.61.81.31.71.41.61.31.1-0.2
Mn content in liver0.10.10.9-0.20.30.30.30.30.00.1-0.10.1-0.1-0.2-1.0
Na content in liver1.01.11.8-1.11.21.21.11.31.10.91.01.11.00.90.3
Rb content in liver0.20.20.90.90.20.2-0.10.1-0.50.30.10.70.5-0.1-0.6
Se content in liver0.10.11.2-0.10.20.20.30.1-0.10.1-0.2-0.1-0.3-0.4-1.1
Sr content in liver1.21.11.70.1-0.9-0.9-0.9-0.7-0.8-1.3-1.1-1.3-1.3-1.2-1.3
Zn content in liver0.10.21.01.0-0.3-0.3-0.3-0.4-0.40.40.1-0.1-0.1-0.20.2
Bone: minimum diameter1.62.97.12.7-2.1-2.1-2.1-2.1-2.2-1.5-1.2-0.8-0.6-1.2-0.1
Time in familiar zone, hab. session 10.30.30.60.2-0.5-0.5-0.4-0.5-0.4-0.5-0.7-0.8-0.8-0.6-0.4
Time in novel zone, hab. session 10.00.00.2-0.10.20.2-0.00.20.10.00.20.10.1-0.1-0.4
Total zone transitions, hab. session 10.20.20.4-0.40.60.60.40.60.50.60.50.50.40.40.3
Total locomotion distance, hab. session 10.10.10.40.60.10.1-0.10.1-0.00.60.50.40.40.30.6
Locomotion velocity, hab. session 10.20.30.80.60.30.30.10.20.10.90.70.70.60.50.8
Time in familiar zone, hab. session 20.10.10.2-0.50.30.30.40.30.40.30.3-0.1-0.10.20.1
Time in novel zone, hab. session 20.00.00.1-0.10.10.10.10.20.0-0.10.00.30.30.10.1
Total zone transitions, hab. session 20.30.30.80.30.40.40.40.40.30.80.90.90.90.60.3
Total locomotion distance, hab. session 20.20.31.21.1-0.1-0.1-0.2-0.0-0.30.60.80.60.50.20.2
Locomotion velocity, hab. session 20.20.31.61.3-0.1-0.1-0.3-0.1-0.40.60.70.60.50.20.2
Novel to familiar place preference ratio3.64.05.12.0-2.3-2.3-2.2-2.1-2.1-2.0-1.9-1.8-1.7-1.9-1.5
Novelty place preference4.04.35.72.0-2.4-2.4-2.3-2.2-2.2-2.1-2.0-1.9-1.8-2.0-1.5
Time in novel zone, NPP test3.23.44.61.8-2.1-2.1-2.1-1.9-2.0-1.9-1.7-1.7-1.6-1.8-1.4
Total zone transitions, NPP test2.02.94.7-0.71.91.91.51.61.51.92.02.22.11.81.1
Total locomotion distance, NPP test1.62.14.0-0.01.41.41.11.41.12.01.91.81.81.51.1
Locomotion velocity, NPP test0.81.22.40.31.01.00.70.90.71.61.51.41.41.10.9
Intraocular pressure0.50.71.50.60.50.50.30.50.31.20.81.21.20.91.1
Delta distance traveled before/after self-admin0.90.91.6-0.91.31.30.81.21.11.21.00.60.50.70.1
Delta ambulatory time before/after self-admin0.81.01.6-1.01.21.21.01.31.11.21.10.50.50.70.1
Parametrial fat weight0.20.51.91.4-0.8-0.8-0.6-0.8-0.80.10.0-0.7-0.7-0.6-0.3
Pavlov. Cond. lever latency2.73.44.7-1.31.61.62.22.01.71.82.02.02.12.01.8
Pavlov. Cond. magazine entry latency2.43.14.11.4-1.4-1.4-2.0-1.9-1.8-1.8-2.0-1.8-1.8-1.9-1.7
Pavlov. Cond. change in total contacts1.11.12.10.5-0.7-0.7-1.3-1.1-0.8-1.0-1.3-1.4-1.4-1.2-0.9
Pavlov. Cond. index score3.03.85.71.9-1.7-1.7-2.4-2.2-2.0-1.7-1.9-1.9-2.0-2.1-1.8
Pavlov. Cond. latency score3.24.05.91.8-1.8-1.8-2.4-2.2-2.0-1.8-2.0-2.0-2.1-2.1-1.8
Pavlov. Cond. lever contacts1.01.22.10.9-0.8-0.8-1.4-1.2-1.0-0.8-1.1-1.2-1.2-1.2-1.1
Pavlov. Cond. magazine entry number3.54.45.8-1.61.91.92.42.22.02.02.42.22.32.21.8
Pavlov. Cond. intertrial magazine entries0.10.10.50.7-0.3-0.30.1-0.0-0.10.50.50.20.30.10.2
Pavlov. Cond. lever-magazine prob. diff.2.73.34.71.7-1.6-1.6-2.2-2.0-1.9-1.7-1.9-1.7-1.8-1.9-1.7
Pavlov. Cond. response bias2.63.34.61.4-1.6-1.6-2.2-2.0-1.7-1.7-2.0-2.0-2.0-1.9-1.5
Pavlov. Cond. lever latency0.20.30.8-0.9-0.2-0.2-0.1-0.20.2-0.6-0.8-0.7-0.7-0.4-0.6
Pavlov. Cond. magazine entry latency3.23.95.0-1.62.02.02.02.22.12.22.21.71.72.01.9
Pavlov. Cond. change in total contacts0.81.22.1-0.51.01.00.91.10.91.01.31.31.31.31.4
Pavlov. Cond. index score1.11.42.3-0.41.11.11.01.21.01.51.51.21.21.21.4
Pavlov. Cond. latency score1.11.42.4-0.41.11.11.01.21.01.51.51.21.31.21.4
Pavlov. Cond. lever contacts0.20.30.80.80.30.30.20.3-0.00.70.90.80.80.50.7
Pavlov. Cond. magazine entry number2.63.24.41.6-1.7-1.7-1.9-2.1-1.9-1.9-2.1-1.5-1.5-1.8-1.6
Pavlov. Cond. intertrial magazine entries0.30.51.51.2-0.5-0.5-0.7-0.9-0.9-0.4-0.60.20.1-0.5-0.8
Pavlov. Cond. lever-magazine prob. diff.1.21.62.5-0.71.21.21.11.41.21.51.61.21.21.31.5
Pavlov. Cond. response bias0.60.81.5-0.10.80.80.80.90.71.11.20.90.90.91.1
Time in closed arm before self-admin0.00.00.1-0.20.10.10.0-0.2-0.1-0.4-0.4-0.10.0-0.2-0.1
Time in closed arm after self-admin0.10.10.8-0.90.10.10.60.30.4-0.20.1-0.3-0.2-0.0-0.1
Time in open arm before self-admin0.91.02.31.5-1.5-1.5-1.0-1.2-1.1-0.8-0.0-0.5-0.4-0.6-0.1
Time in open arm after self-admin0.20.20.3-0.10.50.50.00.30.30.40.30.50.50.50.5
Bone: periosteal estimation0.71.55.32.3-1.3-1.3-1.2-1.2-1.2-0.20.10.40.80.32.0
Bone: periosteal perimeter3.05.28.93.0-2.8-2.8-3.0-2.7-2.7-2.2-1.9-1.5-1.2-1.60.1
Bone: post-yield work0.20.31.20.10.00.00.10.10.20.10.70.60.80.61.1
Progressive ratio test 1 active lever presses0.50.71.1-0.80.90.91.01.00.80.80.90.60.60.60.1
Progressive ratio test 1 breakpoint0.40.50.9-0.70.80.80.90.90.80.80.80.60.50.50.1
Progressive ratio test 1 inactive lever presses0.20.20.60.60.30.30.50.4-0.00.80.50.50.40.1-0.6
Progressive ratio test 2 active lever presses0.30.30.7-0.20.60.60.40.60.50.90.80.50.50.50.5
Progressive ratio test 2 breakpoint0.30.40.8-0.20.70.70.50.70.60.90.80.60.50.60.5
Progressive ratio test 2 inactive lever presses0.00.00.0-0.10.10.1-0.00.10.20.20.1-0.0-0.00.10.1
Incentive Sensitization - Responses0.00.10.40.6-0.1-0.1-0.2-0.2-0.10.40.2-0.0-0.0-0.10.2
Incentive Sensitization - Breakpoint0.00.10.30.5-0.0-0.0-0.2-0.2-0.10.40.1-0.0-0.0-0.00.3
Sum of active levers in priming session hrs 5-60.70.61.60.3-0.7-0.7-1.1-0.8-0.4-0.5-0.8-1.3-1.2-0.70.0
Progressive ratio0.91.43.1-0.71.01.00.80.81.11.21.01.31.41.51.8
Food seeking constrained by brief footshock0.20.21.0-0.4-0.0-0.0-0.2-0.1-0.1-0.5-0.7-0.6-0.7-0.5-1.0
Seeking ratio, punishment vs. effort0.40.61.70.3-0.5-0.5-0.5-0.4-0.8-1.0-0.7-0.7-0.8-1.0-1.3
Retroperitoneal fat weight0.21.06.52.5-0.6-0.6-0.1-0.5-0.91.10.60.70.80.10.7
Reaction time number correct1.52.85.2-0.61.91.91.71.51.31.71.92.32.21.60.8
Reaction time mean minus median0.00.10.3-0.50.30.30.20.40.50.4-0.0-0.3-0.30.10.3
Reaction time mean minus median AUC0.00.10.2-0.20.40.4-0.00.30.30.30.00.10.00.20.1
Reaction time num false alarms0.10.20.40.4-0.6-0.6-0.5-0.6-0.3-0.4-0.3-0.5-0.3-0.10.4
Reaction time num false alarms AUC0.00.00.3-0.0-0.2-0.2-0.1-0.20.10.00.1-0.1-0.00.20.5
Reaction time trials correct on left1.52.85.2-0.61.91.91.71.51.31.71.92.32.21.60.8
Reaction time trials on left1.63.05.5-0.61.91.91.71.61.31.82.02.32.21.70.8
Reaction time mean0.10.10.50.7-0.4-0.4-0.5-0.2-0.40.1-0.1-0.3-0.4-0.20.0
Reaction time mean AUC0.10.10.40.60.10.1-0.10.1-0.10.50.40.30.20.20.2
Median of all reaction times0.10.20.80.9-0.5-0.5-0.6-0.3-0.5-0.0-0.1-0.2-0.2-0.3-0.1
Reaction time omissions0.10.20.5-0.30.50.50.50.70.40.50.40.50.40.4-0.3
Reaction time false alarm rate0.70.91.90.3-1.2-1.2-0.9-1.0-0.6-1.0-1.0-1.4-1.2-0.7-0.1
Reaction time premature initiation rate0.10.10.7-0.80.20.20.30.40.60.10.2-0.3-0.30.20.2
Reaction time premature initiations0.81.41.8-1.01.31.31.21.21.31.21.41.11.11.20.7
Std. dev. reaction times0.20.30.6-0.50.70.70.40.80.70.80.50.30.20.50.5
Reaction time trials completed1.63.05.5-0.61.91.91.71.61.31.82.02.32.21.70.8
Reaction time trials AUC1.42.75.1-0.51.81.81.61.51.21.71.92.32.11.60.7
Run reversals in cocaine runway, females0.20.20.3-0.30.50.50.50.40.40.40.60.40.40.50.4
Run reversals in cocaine runway, males1.31.31.61.2-1.3-1.3-1.2-1.1-1.2-0.8-1.1-1.3-1.2-1.2-0.7
Latency to leave start box in cocaine runway0.91.02.2-0.31.01.00.90.80.91.51.00.90.91.01.4
Latency to leave start box in cocaine runway, F2.22.54.5-0.21.61.61.41.31.22.11.81.81.81.61.7
Latency to leave start box in cocaine runway, M0.20.20.5-0.1-0.5-0.5-0.3-0.4-0.1-0.2-0.6-0.7-0.7-0.30.2
Std. dev. time between licks in bursts2.02.84.9-0.61.81.81.61.71.21.71.92.22.11.60.7
Total sessions with >9 infusions0.40.40.7-0.90.70.70.70.70.80.50.80.40.40.60.2
Short access day 1 total inactive lever presses0.50.71.6-0.20.60.60.70.70.71.01.20.70.80.91.2
Short access day 10 total inactive lever presses0.10.21.21.1-0.3-0.3-0.2-0.3-0.60.0-0.10.20.1-0.3-0.6
Short access day 1 total infusions0.30.42.0-1.40.60.60.80.60.90.10.50.10.10.5-0.1
Short access day 10 total infusions0.10.10.30.00.30.30.20.40.20.50.30.0-0.1-0.0-0.6
Short access total infusions0.20.30.8-0.90.60.60.70.70.70.40.50.1-0.00.2-0.5
Short access day 1 locomotion0.10.10.9-0.90.30.3-0.00.20.4-0.3-0.1-0.1-0.10.1-0.3
Short access day 10 total locomotion0.10.20.5-0.6-0.0-0.0-0.10.10.0-0.5-0.5-0.7-0.7-0.5-0.7
Short access total locomotion0.10.10.5-0.70.10.1-0.00.10.2-0.3-0.1-0.5-0.4-0.2-0.4
One hour access (0.3 mA shock)0.00.10.30.40.20.20.00.10.00.60.30.0-0.1-0.1-0.1
Compulsive drug intake0.20.31.11.0-0.6-0.60.3-0.6-0.7-0.1-0.1-0.1-0.2-0.4-0.5
One hour access (shock baseline)0.10.10.30.10.40.4-0.30.30.20.60.50.10.00.10.0
Social response proportion1.11.31.7-1.31.21.21.21.11.20.71.01.21.21.20.9
Social responses0.20.30.6-0.80.60.60.60.50.5-0.10.60.60.60.50.1
Social time0.00.10.1-0.10.00.00.1-0.00.1-0.00.30.30.40.30.4
Soleus weight1.13.35.42.3-2.0-2.0-1.7-1.9-2.2-1.5-1.2-1.5-1.5-1.9-1.8
Bone: stiffness0.40.73.01.3-0.3-0.3-0.4-0.4-0.30.40.50.81.00.71.7
Tibialis anterior weight0.10.41.11.0-0.8-0.8-0.5-0.7-0.7-0.20.0-0.5-0.5-0.50.0
Time to tail flick, vehicle, before self-admin0.70.81.4-0.81.21.20.71.20.80.80.51.00.80.60.1
Time to tail flick, vehicle, after self-admin0.30.41.7-0.60.40.40.50.60.70.40.60.40.50.71.3
Time to tail flick, test, before self-admin1.51.52.9-1.21.61.61.71.71.21.40.90.90.80.80.3
Time to tail flick, test, after self-admin1.71.74.5-2.11.61.61.91.71.50.70.70.70.60.80.2
Delta time to tail flick, vehicle, before/after SA0.10.10.30.5-0.4-0.40.1-0.4-0.20.10.2-0.3-0.2-0.10.5
Delta time to tail flick, test, before/after SA0.50.51.2-0.1-0.8-0.8-0.9-0.8-0.3-1.1-0.7-0.8-0.7-0.30.1
Tibia length6.818.839.56.3-5.1-5.1-5.1-5.0-5.4-3.8-3.5-2.7-2.4-3.6-1.6
Ambulatory time before self-admin0.20.20.80.5-0.1-0.1-0.0-0.5-0.7-0.5-0.90.0-0.1-0.5-0.7
Ambulatory time after self-admin0.30.30.9-0.20.90.90.70.50.40.80.30.60.50.3-0.1
Bone: tissue strength0.40.42.31.5-0.5-0.5-0.3-0.4-0.70.10.30.70.80.30.9
Total heroin consumption0.20.21.7-0.1-0.2-0.2-0.3-0.10.1-0.1-0.1-0.00.30.51.3
Bone: trabecular number0.30.40.60.4-0.6-0.6-0.8-0.7-0.6-0.7-0.6-0.7-0.7-0.7-0.7
Bone: trabecular spacing2.63.45.7-0.51.61.61.91.71.52.12.22.42.42.01.6
Bone: trabecular thickness3.94.96.71.5-2.3-2.3-2.6-2.3-2.1-2.4-2.2-2.4-2.4-2.2-1.4
Bone: trabecular tissue density1.42.12.7-1.51.41.41.61.61.61.31.21.41.41.51.4
Water consumed over 24 hours1.21.62.30.5-1.2-1.2-1.1-1.1-1.1-1.4-1.5-1.5-1.5-1.3-1.4
Number of responses in last shaping day0.20.20.7-0.80.60.60.20.40.50.20.20.0-0.00.2-0.1