Zfp869

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver isoform ratio XM_017600339.3 0.04 0.03 3.0e-03 0.01 0 0 0.01 3.7e-02 2.1e-01 1.5e-01 3.3e-02
2 NAcc gene expression Zfp869 0.04 0.02 4.2e-04 0.03 0.02 0.02 0.02 4.4e-05 1.5e-04 1.5e-03 2.3e-04
3 Adipose gene expression Zfp869 0.42 0.14 0.0e+00 0.16 0.12 0.19 0.2 1.1e-17 5.7e-13 5.2e-21 6.3e-22
4 Adipose intron excision ratio chr16_19727159_19729418 0.03 0.02 7.4e-03 0.01 0.01 0 0 1.6e-02 6.0e-02 2.4e-01 7.4e-02
5 pVTA gene expression Zfp869 0.05 0.04 3.7e-03 0.03 0.04 0.02 0.03 2.5e-03 7.2e-04 9.0e-03 1.3e-03
6 PL gene expression Zfp869 0.07 0.04 8.9e-06 0.04 0.05 0.04 0.04 3.8e-05 3.5e-06 1.3e-05 3.4e-05
7 NAcc intron excision ratio chr16_19727159_19729418 0.03 0.02 3.5e-04 0.02 0.01 0.01 0.01 2.3e-04 2.1e-03 3.1e-03 2.2e-03
8 Adipose mRNA stability Zfp869 0.04 0.03 2.8e-03 0.01 0.01 0.01 0.01 6.7e-03 2.0e-02 9.3e-03 2.2e-02
9 Liver gene expression Zfp869 0.22 0.13 2.2e-05 0.03 0.02 0.02 0.02 5.7e-04 9.0e-04 1.0e-03 2.2e-03
10 pVTA intron excision ratio chr16_19804673_19809005 0.03 0.02 1.7e-03 0 0.02 0 0.01 2.6e-01 7.6e-03 1.4e-01 8.9e-02
11 LHb mRNA stability Zfp869 0.5 0.17 1.9e-05 0.06 0.17 0.15 0.06 1.3e-02 9.0e-05 2.0e-04 1.5e-02
12 Eye isoform ratio XM_017600339.3 0.43 0.23 4.7e-03 0.04 0.11 0.09 0.05 8.4e-02 1.1e-02 1.7e-02 5.3e-02
13 Brain gene expression Zfp869 0.04 0.03 8.8e-04 0.01 0.02 0.01 0.01 7.7e-02 2.5e-03 2.2e-02 1.5e-02
14 Liver alternative polyA XM_039095265.2 0.1 0.05 1.9e-06 0.02 0.03 0.04 0.04 1.4e-03 3.1e-04 3.4e-05 2.7e-05
15 Liver alternative polyA NM_001408730.1 0.12 0.07 1.4e-07 0.03 0.03 0.04 0.04 6.9e-04 2.1e-04 2.0e-05 1.5e-05
16 Brain intron excision ratio chr16_19798795_19804334 0.04 0.03 3.0e-04 0.05 0.04 0.04 0.04 3.6e-05 6.8e-05 1.8e-04 5.1e-05
17 NAcc intron excision ratio chr16_19798795_19804334 0.02 0.01 5.9e-04 0.03 0.02 0.02 0.02 4.7e-05 4.2e-04 2.8e-04 2.0e-04
18 Liver intron excision ratio chr16_19807562_19807827 0.23 0.11 3.5e-03 0.02 0.01 0 0.01 2.6e-03 4.7e-02 8.8e-02 7.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density3.56.012.8-2.7-2.8-3.3-2.9-3.4-3.6-2.6-3.5-3.31.0-1.3-2.4-2.50.9-0.9-1.1-1.30.0
Area under the delay curve0.50.62.90.20.00.3-0.1-0.20.10.80.10.7-0.4-1.3-0.1-0.01.7-1.7-0.9-0.70.0
BMI with tail0.82.76.8-2.6-2.4-2.0-2.3-1.8-1.3-1.9-0.8-0.22.4-2.51.21.10.2-0.21.11.20.0
BMI without tail1.64.811.3-2.8-3.2-2.8-3.1-2.4-1.8-2.8-1.4-0.83.4-2.71.51.4-0.30.31.82.00.0
Body weight2.912.528.1-5.3-5.2-5.0-5.2-4.8-4.0-4.2-3.5-2.24.2-4.80.40.21.2-1.20.91.00.0
Weight adjusted by age1.21.94.5-1.9-1.4-1.4-1.5-1.0-1.0-1.9-0.8-1.22.1-0.20.90.8-1.51.61.61.80.0
Bone surface1.83.26.5-2.3-2.3-2.4-2.3-2.6-2.6-1.9-2.4-2.11.0-1.5-1.4-1.50.9-0.9-0.7-0.70.0
Bone volume2.64.79.6-2.8-2.9-3.1-2.8-3.1-3.1-2.6-3.0-2.71.5-1.5-1.5-1.60.5-0.5-0.4-0.40.0
Breakpoint value in progressive ratio session0.60.71.7-0.20.80.90.71.01.10.61.31.20.10.11.21.2-0.40.40.70.70.0
Number of licking bursts0.91.55.60.80.50.10.5-0.10.11.20.11.0-1.3-1.2-0.8-0.82.4-2.4-1.9-1.80.0
Context. condit. distance diff. score0.50.61.71.00.50.10.50.0-0.20.6-0.4-0.4-1.20.5-1.3-1.20.7-0.7-1.2-1.30.0
Locomotion velocity, session 10.50.62.10.80.40.90.40.71.00.91.11.5-0.0-0.71.01.10.4-0.40.30.20.0
Locomotion distance, session 10.40.61.51.10.60.50.70.30.30.90.10.4-1.0-0.1-0.6-0.61.0-1.0-1.1-1.20.0
Locomotion velocity, session 20.60.73.3-0.2-0.8-0.3-0.8-0.30.2-0.10.31.01.1-1.81.31.30.6-0.60.60.50.0
Locomotion distance, session 20.50.71.71.31.01.01.10.80.81.20.70.8-1.20.3-0.3-0.30.7-0.7-0.9-0.90.0
Locomotion velocity, session 31.51.75.02.21.71.81.81.81.71.61.71.5-1.31.20.40.5-0.30.3-0.2-0.00.0
Locomotion distance, session 30.50.51.90.3-0.1-0.4-0.1-0.5-0.8-0.5-0.9-1.2-0.50.8-1.4-1.3-0.10.1-0.7-0.70.0
Stereotopy head waving bouts, day 33.44.09.52.52.22.02.21.51.42.81.11.6-3.10.3-1.3-1.22.3-2.3-2.6-2.50.0
Stereotopy head waving duration, day 32.02.45.31.91.61.61.71.21.22.31.01.6-2.2-0.2-0.7-0.62.0-2.0-1.9-1.80.0
Locomotion velocity, session 70.91.02.11.31.21.51.31.41.41.01.41.0-0.71.10.60.6-0.70.70.30.60.0
Locomotion distance, session 70.40.61.20.61.11.01.11.00.91.10.90.9-1.00.40.00.00.3-0.3-0.5-0.40.0
Stereotopy head waving bouts, day 70.30.30.80.50.40.30.40.0-0.10.5-0.2-0.1-0.90.3-0.9-0.90.6-0.6-0.9-0.90.0
Stereotopy head waving duration, day 70.10.10.40.60.50.60.50.40.30.50.30.3-0.50.2-0.1-0.10.2-0.2-0.3-0.20.0
Locomotion velocity, session 82.53.06.92.62.32.42.32.32.32.52.22.2-1.80.90.50.60.4-0.4-0.6-0.50.0
Locomotion distance, session 80.40.51.41.00.50.30.60.10.10.8-0.00.2-1.00.0-0.9-0.81.0-0.9-1.2-1.10.0
Degree of sensitization distance0.90.92.80.41.01.21.11.21.51.31.51.7-0.4-0.11.11.10.2-0.10.20.40.0
Degree of sensitization stereotypy0.30.41.1-0.5-0.5-0.7-0.6-0.8-0.9-0.7-0.9-1.00.10.1-0.8-0.8-0.00.0-0.3-0.20.0
Conditioned locomotion0.20.20.70.20.2-0.00.3-0.1-0.20.3-0.3-0.1-0.70.0-0.8-0.80.7-0.7-0.8-0.90.0
Cocaine response after cond. corrected0.20.31.20.70.40.30.50.2-0.10.1-0.2-0.6-0.61.1-0.7-0.7-0.50.5-0.2-0.30.0
Cocaine response after cond. not corrected0.60.71.71.31.21.21.21.10.90.90.80.4-1.01.3-0.2-0.1-0.50.5-0.1-0.20.0
Cocaine response before conditioning1.21.54.60.91.31.51.21.51.81.51.92.1-0.4-0.21.31.40.2-0.30.30.30.0
Saline control response0.20.20.80.2-0.5-0.4-0.5-0.4-0.6-0.7-0.5-0.90.40.3-0.3-0.2-0.60.60.30.30.0
Bone: connectivity density3.65.611.8-2.6-3.0-3.3-3.0-3.3-3.4-2.8-3.3-3.11.5-1.5-1.9-1.90.6-0.6-0.6-0.80.0
Bone: cortical apparent density0.20.30.8-0.3-0.3-0.0-0.3-0.00.0-0.50.2-0.00.80.00.70.7-0.80.80.90.90.0
Bone: cortical area3.65.515.0-3.9-3.2-3.2-3.1-2.9-2.8-3.2-2.5-2.72.9-1.4-0.0-0.2-0.90.91.21.20.0
Bone: cortical porosity0.20.20.7-0.20.10.30.10.20.50.30.50.80.2-0.60.70.70.3-0.30.20.20.0
Bone: cortical porosity0.10.10.7-0.3-0.00.1-0.1-0.00.20.30.20.6-0.0-0.80.30.30.7-0.7-0.2-0.20.0
Bone: cortical thickness2.54.110.4-3.2-2.6-2.9-2.6-2.7-2.8-2.6-2.6-2.71.8-1.0-0.9-1.1-0.30.30.20.30.0
Bone: cortical thickness2.93.48.2-1.6-1.2-1.9-1.1-2.0-2.4-0.9-2.5-2.4-0.7-0.3-2.8-2.91.4-1.4-2.1-2.10.0
Bone: cortical tissue density0.20.20.7-0.2-0.10.1-0.20.10.2-0.30.30.10.60.10.70.7-0.80.80.80.80.0
Condit. Reinf. active minus inactive responses1.51.63.0-0.8-0.9-1.2-0.8-1.4-1.5-0.3-1.6-1.1-0.5-1.0-1.7-1.71.7-1.6-1.7-1.50.0
Condit. Reinf. active-inactive response ratio2.12.35.2-1.2-1.1-1.8-1.1-1.8-2.1-1.0-2.2-2.0-0.4-0.3-2.2-2.31.0-0.9-1.6-1.30.0
Condit. Reinf. active responses1.21.53.7-0.8-0.9-1.1-0.9-1.4-1.3-0.2-1.4-0.6-0.3-1.5-1.3-1.31.9-1.9-1.5-1.50.0
Condit. Reinf. inactive responses0.30.41.6-0.4-0.9-0.4-0.9-0.5-0.2-0.4-0.10.41.0-1.30.80.80.3-0.40.50.30.0
Incentive salience index mean1.31.55.1-0.8-0.9-0.9-0.9-1.3-1.00.1-1.1-0.1-0.3-2.0-0.9-1.02.3-2.3-1.6-1.50.0
Condit. Reinf. lever presses1.11.56.8-0.5-0.8-0.5-0.7-0.9-0.40.6-0.40.9-0.1-2.6-0.1-0.12.5-2.5-1.3-1.40.0
Condit. Reinf. active minus inactive responses0.10.10.80.20.20.30.30.30.1-0.20.1-0.3-0.10.9-0.1-0.1-0.70.70.50.10.0
Condit. Reinf. active-inactive response ratio0.10.10.3-0.6-0.5-0.4-0.4-0.3-0.3-0.5-0.3-0.30.4-0.20.10.1-0.20.20.40.20.0
Condit. Reinf. active responses0.60.81.81.31.11.31.11.21.10.61.00.5-0.51.30.40.4-0.90.90.70.30.0
Condit. Reinf. inactive responses2.02.65.12.22.02.21.92.22.11.32.01.3-0.81.91.11.2-1.41.41.10.90.0
Condit. Reinf. lever presses0.60.92.10.60.61.10.71.11.30.61.41.30.30.11.41.4-0.60.61.00.80.0
Condit. Reinf. lever reinforcers received0.50.61.10.80.81.00.81.00.90.30.90.5-0.11.00.70.7-1.01.00.90.60.0
Conditioned reinforcement - actives1.11.84.4-1.7-2.0-1.8-1.9-1.5-1.4-2.1-1.2-1.31.8-0.70.30.2-0.80.81.01.00.0
Conditioned reinforcement - inactives3.85.512.4-2.9-3.4-3.3-3.4-2.9-2.8-3.5-2.4-2.53.0-1.30.0-0.1-1.01.11.41.30.0
Conditioned locomotion0.81.02.8-1.1-1.7-1.4-1.5-1.2-1.1-1.5-0.9-0.81.4-0.80.20.2-0.30.30.70.80.0
Patch foraging indifference point 0 sec0.61.15.9-1.3-0.9-0.3-0.6-0.30.30.20.51.50.7-2.41.21.11.4-1.50.0-0.00.0
Patch foraging indifference point AUC1.11.66.00.31.11.41.11.41.81.62.02.4-0.3-0.61.61.60.6-0.50.20.50.0
Delay disc. indifference point, 0s delay2.83.05.92.02.11.91.91.61.92.41.82.3-2.1-0.3-0.00.12.2-2.1-1.5-1.40.0
Delay disc. indifference point, 16s delay0.60.71.70.80.81.10.60.70.91.30.91.3-0.8-0.50.20.31.1-1.1-0.6-0.50.0
Delay disc. indifference point, 2s delay1.01.14.00.81.00.90.80.40.61.40.40.9-1.3-0.7-0.4-0.42.0-2.0-1.4-1.20.0
Delay disc. indifference point, 24s delay0.30.32.00.2-0.50.0-0.6-0.4-0.10.3-0.10.50.3-1.40.30.41.2-1.2-0.2-0.10.0
Delay disc. indifference point, 4s delay0.20.21.20.1-0.30.1-0.3-0.3-0.10.4-0.10.4-0.0-1.10.00.11.1-1.1-0.4-0.30.0
Delay disc. indifference point, 8s delay0.40.42.2-0.1-0.10.2-0.1-0.10.20.60.31.00.1-1.50.50.51.3-1.3-0.3-0.20.0
Indifference point function ln k1.32.24.6-1.2-2.1-2.1-1.9-2.1-2.1-2.0-2.2-2.11.1-0.8-1.0-1.10.1-0.1-0.1-0.30.0
Indifference point function log k1.32.24.6-1.2-2.1-2.1-1.9-2.1-2.1-2.0-2.2-2.11.1-0.8-1.0-1.10.1-0.1-0.1-0.30.0
Patch foraging total patch changes 0 sec0.81.58.5-1.7-1.3-0.7-1.1-0.7-0.0-0.10.21.41.1-2.91.31.31.5-1.60.20.10.0
Patch foraging total patch changes 12 sec0.81.04.50.20.40.90.60.81.31.21.42.1-0.1-1.21.31.31.0-0.90.00.10.0
Patch foraging total patch changes 18 sec1.52.36.60.81.82.01.72.02.21.82.52.6-0.70.21.61.60.0-0.00.30.60.0
Patch foraging total patch changes 24 sec0.30.52.1-0.40.40.60.60.60.80.91.01.5-0.5-0.70.50.50.9-0.9-0.4-0.30.0
Patch foraging total patch changes 6 sec1.01.56.9-0.00.30.90.30.71.41.21.62.60.1-1.91.71.71.3-1.30.10.20.0
Patch foraging time to switch 0 sec0.30.72.31.51.31.21.11.00.90.90.80.5-0.61.00.20.3-0.50.50.20.10.0
Patch foraging water rate 0 sec0.51.04.3-1.4-1.2-0.8-0.9-0.9-0.5-0.1-0.50.50.3-2.10.10.11.7-1.6-0.6-0.60.0
Patch foraging water rate 12 sec0.71.43.0-1.7-1.6-1.7-1.6-1.7-1.5-1.2-1.5-1.10.8-1.4-0.6-0.60.7-0.7-0.4-0.40.0
Patch foraging water rate 18 sec0.61.02.7-1.0-1.1-1.0-0.8-1.1-0.9-0.1-0.9-0.2-0.0-1.6-0.6-0.71.6-1.6-1.1-0.90.0
Patch foraging water rate 24 sec2.02.85.3-1.9-2.1-2.2-1.9-2.3-2.1-1.4-2.2-1.40.6-2.0-1.3-1.31.7-1.7-1.1-1.00.0
Patch foraging water rate 6 sec0.91.33.0-1.6-1.7-1.7-1.6-1.6-1.4-1.3-1.3-0.91.0-1.4-0.3-0.40.6-0.6-0.1-0.00.0
Seeking ratio, delayed vs. immediate footshock0.40.52.71.70.70.60.60.80.90.40.91.1-0.4-0.00.40.50.2-0.20.2-0.00.0
Distance traveled before self-admin0.30.31.0-0.2-0.4-0.2-0.5-0.10.2-0.40.40.80.8-0.91.01.00.1-0.10.80.70.0
Distance traveled after self-admin0.30.41.1-0.8-0.9-0.6-0.8-0.5-0.3-0.8-0.2-0.01.1-0.60.70.7-0.30.30.90.80.0
Extensor digitorum longus weight0.10.20.90.40.00.3-0.00.00.30.50.30.80.0-1.00.40.40.7-0.7-0.2-0.20.0
Bone: elastic displacement0.10.10.40.0-0.3-0.3-0.2-0.3-0.4-0.1-0.4-0.3-0.20.0-0.6-0.60.3-0.3-0.5-0.40.0
Bone: elastic work1.01.33.0-1.7-1.7-1.5-1.6-1.5-1.4-1.4-1.2-1.01.3-1.1-0.1-0.10.1-0.10.20.30.0
Bone: endosteal estimation0.10.31.7-0.5-0.8-0.4-0.6-0.4-0.1-0.2-0.00.40.7-1.30.70.60.5-0.50.30.10.0
Bone: endosteal perimeter0.40.92.2-1.4-1.4-1.1-1.3-1.0-0.9-1.3-0.7-0.71.5-0.70.60.5-0.60.50.90.80.0
Epididymis fat weight1.34.49.9-3.0-3.0-2.7-3.0-2.5-2.0-2.8-1.7-1.23.1-2.31.00.9-0.50.51.61.60.0
Delta time in closed arm before/after self-admin0.40.41.70.3-0.10.30.10.10.30.60.51.0-0.3-1.20.20.21.3-1.3-0.5-0.50.0
Delta time in open arm before/after self-admin0.30.20.90.21.00.60.60.60.50.30.30.0-0.20.90.10.1-0.70.70.30.20.0
Diff in mean of infusions in LGA sessions1.21.44.9-0.50.20.70.10.81.20.21.61.61.1-0.62.22.2-0.70.71.61.70.0
Delay discount exponential model param0.40.42.2-0.00.3-0.10.30.40.2-0.50.2-0.40.21.30.10.1-1.51.50.80.50.0
Extinction: sum of active levers before priming0.10.10.3-0.40.1-0.0-0.0-0.10.10.20.20.4-0.0-0.60.10.10.6-0.5-0.2-0.10.0
Active lever presses in extinction session 60.20.20.30.40.50.60.30.50.50.30.50.3-0.10.60.30.3-0.40.40.40.20.0
Bone: final force2.43.812.6-3.5-2.8-2.6-2.7-2.5-2.0-1.8-1.8-1.02.3-2.90.40.20.8-0.90.30.30.0
Bone: final moment2.33.711.9-3.4-2.8-2.6-2.7-2.5-2.1-1.9-1.8-1.12.2-2.80.30.10.8-0.80.30.30.0
Food consumed during 24 hour testing period0.20.30.80.00.20.20.30.0-0.00.5-0.00.2-0.7-0.1-0.6-0.60.8-0.8-0.9-0.80.0
Glucose0.50.72.5-1.2-0.6-0.2-0.50.00.4-0.20.70.81.2-1.01.61.5-0.30.31.11.10.0
Heart weight1.52.36.7-0.6-1.3-1.8-1.6-1.9-2.3-1.6-2.4-2.60.20.0-2.0-2.00.3-0.2-0.9-0.80.0
Delay discount hyperbolic model param0.50.52.8-0.20.1-0.20.10.30.1-0.70.0-0.60.31.40.20.1-1.71.60.90.60.0
Intermittent access intake day 1-15 change0.71.53.9-1.7-1.2-1.5-1.2-1.2-1.5-1.8-1.5-2.00.90.6-0.8-0.8-1.11.10.40.30.0
Intermittent access intake escalation0.71.33.7-1.5-1.3-1.5-1.1-1.2-1.5-1.8-1.5-1.90.70.5-0.9-0.9-1.01.00.20.10.0
Intermittent access intake escalation 21.41.64.0-1.9-1.7-1.8-1.6-1.4-1.4-2.0-1.3-1.51.5-0.3-0.1-0.1-0.90.90.90.80.0
Intermitt. access day 1 inactive lever presses0.31.04.00.2-0.6-0.6-0.6-0.2-0.5-1.3-0.4-1.21.01.10.20.2-2.02.01.21.10.0
Intermitt. access day 15 inactive lever presses0.20.52.00.6-0.1-0.10.00.1-0.2-0.7-0.3-0.90.11.4-0.3-0.3-1.41.40.50.40.0
Intermitt. access escalation Index0.40.62.10.90.30.30.50.10.20.80.00.5-1.0-0.5-0.6-0.61.4-1.4-1.2-1.10.0
Intermittent access day 1 total infusions0.20.31.0-0.0-0.20.2-0.20.20.50.10.60.80.6-0.61.01.0-0.10.10.70.70.0
Intermittent access day 15 total infusions0.71.02.2-1.4-1.4-1.4-1.2-1.2-1.3-1.5-1.2-1.40.9-0.1-0.4-0.5-0.60.60.30.30.0
Intermittent access terminal intake (last 3 days)0.50.62.1-1.4-1.1-1.1-1.0-1.0-1.0-1.1-0.9-0.90.8-0.4-0.2-0.2-0.20.20.30.20.0
Intermittent access total infusions0.60.72.0-1.4-1.2-0.9-1.1-0.7-0.7-1.1-0.5-0.51.2-0.50.50.4-0.60.60.80.80.0
Intermittent access day 1 locomotion0.60.82.0-1.1-1.1-0.5-1.0-0.4-0.1-0.70.20.31.4-1.01.21.2-0.40.41.21.20.0
Intermittent access day 15 total locomotion0.20.41.2-1.1-0.9-0.8-0.9-0.8-0.8-0.8-0.7-0.60.8-0.4-0.0-0.0-0.20.20.30.40.0
Intermittent access total locomotion0.81.03.0-1.7-1.4-1.0-1.3-0.8-0.6-1.2-0.4-0.31.5-0.80.80.8-0.60.61.11.20.0
Intermittent access standard deviation0.30.61.6-0.9-1.1-1.2-1.1-0.9-0.9-1.3-0.8-0.90.9-0.3-0.1-0.1-0.50.50.50.50.0
Left kidney weight0.21.13.6-1.0-0.4-0.0-0.50.00.5-0.40.81.21.4-1.31.91.8-0.40.41.41.60.0
Right kidney weight0.94.011.4-2.4-2.1-1.4-2.1-1.0-0.4-2.00.10.43.4-2.02.82.7-1.31.32.73.00.0
Cocaine induced anxiety0.81.23.2-0.30.10.80.41.01.20.21.41.20.80.21.81.7-1.11.11.51.50.0
Post-drug Anxiety0.50.51.20.40.50.90.61.01.00.41.10.90.00.40.90.9-0.60.60.70.70.0
Baseline Anxiety0.70.81.91.30.70.20.60.1-0.10.7-0.3-0.1-1.30.2-1.2-1.21.1-1.1-1.4-1.40.0
Tail length0.62.25.3-1.6-2.3-2.2-2.2-1.9-1.6-2.0-1.3-0.82.1-2.00.50.50.3-0.30.70.90.0
Length with tail1.25.111.0-3.3-3.3-3.1-3.2-3.0-2.6-2.9-2.3-1.82.8-2.70.30.10.4-0.30.80.80.0
Length without tail1.13.49.4-3.1-2.3-2.4-2.3-2.5-2.6-2.2-2.5-2.41.5-1.2-0.9-1.10.1-0.1-0.1-0.10.0
Times rat made contact with spout0.40.52.0-0.0-0.00.00.0-0.3-0.10.7-0.10.5-0.6-1.0-0.4-0.41.4-1.4-1.1-0.90.0
Lifetime Intake0.81.02.6-1.6-1.5-1.3-1.4-1.1-1.0-1.3-0.8-0.71.5-0.80.40.4-0.40.40.90.80.0
Liver weight, left0.10.20.7-0.00.40.20.30.30.2-0.20.2-0.20.10.80.20.2-0.80.90.40.60.0
Liver weight, right1.73.08.0-2.3-2.1-1.8-2.1-1.4-1.1-2.3-0.7-0.82.8-1.21.51.4-1.41.42.22.00.0
Locomotor activity0.81.22.4-1.0-1.3-1.1-1.4-1.5-1.4-0.6-1.4-0.70.4-1.6-0.8-0.81.4-1.4-0.8-0.90.0
Locomotor testing distance0.81.43.1-0.4-1.1-1.2-1.2-1.6-1.6-0.7-1.8-1.4-0.0-0.8-1.5-1.51.1-1.1-1.2-1.20.0
Locomotor testing rearing0.30.61.2-0.4-0.9-0.7-0.9-1.1-1.0-0.2-1.1-0.60.2-1.1-0.6-0.61.1-1.1-0.6-0.70.0
Locomotion in novel chamber0.40.51.7-0.9-0.4-0.9-0.4-0.7-0.4-0.4-0.30.20.2-1.3-0.1-0.11.3-1.3-0.5-0.40.0
Locomotion in novel chamber post-restriction2.03.25.9-1.9-1.7-2.3-1.7-2.4-2.3-1.0-2.4-1.70.2-1.8-1.8-1.92.0-2.0-1.5-1.40.0
Fecal boli incidents, locomotor time 10.10.20.9-0.6-0.3-0.1-0.3-0.20.10.10.30.60.5-0.90.60.60.4-0.30.10.40.0
Change in fecal boli incidents, locomotor task1.41.42.91.71.71.71.61.61.61.51.41.4-1.20.70.40.40.3-0.3-0.2-0.40.0
Time >=10cm from walls, locomotor time 10.70.71.80.10.60.90.61.01.10.51.31.20.30.01.31.3-0.60.61.00.80.0
Bouts of movement, locomotor time 10.10.10.4-0.0-0.20.3-0.20.10.20.20.30.40.4-0.20.60.6-0.30.30.60.50.0
Total resting periods, locomotor time 10.10.10.10.20.00.30.00.20.30.30.30.40.1-0.00.40.4-0.20.20.30.20.0
Rest time, locomotor task time 10.20.30.70.80.50.30.50.30.40.60.50.8-0.7-0.3-0.1-0.10.8-0.8-0.6-0.70.0
Distance moved, locomotor task time 10.20.30.60.50.60.60.60.80.70.20.80.5-0.10.70.50.5-0.70.70.50.50.0
Vertical activity count, locomotor time 10.10.20.6-0.2-0.4-0.4-0.4-0.3-0.3-0.6-0.4-0.50.50.20.10.0-0.70.70.50.40.0
Time >=10cm from walls, locomotor time 20.50.72.10.91.30.51.20.70.40.50.2-0.1-1.51.3-1.0-1.0-0.10.1-0.8-1.10.0
Bouts of movement, locomotor time 20.40.71.60.91.00.91.21.21.20.91.31.2-0.90.50.30.3-0.00.0-0.3-0.10.0
Total resting periods, locomotor time 20.40.71.70.70.91.01.21.11.20.91.31.3-0.70.40.50.50.00.0-0.20.10.0
Rest time, locomotor task time 20.10.10.6-0.20.10.20.00.00.20.50.20.60.0-0.70.30.30.7-0.7-0.0-0.20.0
Distance moved, locomotor task time 20.40.52.30.30.2-0.10.20.30.0-0.70.0-0.50.11.3-0.1-0.1-1.51.50.60.50.0
Vertical activity count, locomotor time 20.40.61.80.1-0.1-0.50.0-0.2-0.6-0.8-0.7-1.2-0.31.4-1.0-1.0-1.11.1-0.2-0.20.0
Light reinforcement 10.10.31.0-0.00.30.50.30.40.60.60.71.00.1-0.60.80.80.3-0.20.30.30.0
Light reinforcement 20.61.02.90.30.91.40.71.11.41.11.51.70.0-0.31.41.4-0.10.10.60.50.0
Bone: marrow area0.10.31.8-0.4-0.8-0.4-0.6-0.4-0.1-0.1-0.10.50.6-1.30.60.50.7-0.70.1-0.00.0
Bone: maximum diameter0.91.75.3-2.3-1.8-1.8-1.7-1.7-1.6-1.7-1.4-1.41.5-1.0-0.0-0.2-0.20.20.50.40.0
Bone: maximum force2.74.815.1-3.9-3.2-3.0-3.1-2.9-2.4-2.2-2.2-1.42.5-3.10.30.10.8-0.80.40.30.0
Bone: maximum moment2.54.313.2-3.6-3.0-2.8-2.9-2.8-2.4-2.2-2.2-1.52.3-2.70.1-0.00.6-0.70.40.30.0
Mean time between licks in bursts0.81.94.5-1.8-2.1-1.8-2.1-1.8-1.5-1.6-1.3-0.81.9-1.90.40.30.3-0.30.60.50.0
Mean num. licks in bursts0.40.61.6-1.1-0.8-0.5-0.8-0.6-0.8-1.0-0.8-1.30.80.5-0.1-0.2-1.11.10.70.80.0
Cd content in liver3.43.78.2-2.2-2.0-2.6-2.0-2.5-2.8-1.9-2.9-2.80.5-0.6-2.2-2.30.7-0.7-1.1-1.00.0
Co content in liver0.10.10.40.00.50.30.60.50.40.50.40.5-0.60.3-0.2-0.20.1-0.1-0.3-0.30.0
Cu content in liver0.91.03.00.90.80.60.90.40.31.10.10.5-1.70.4-1.3-1.21.2-1.2-1.6-1.50.0
Fe content in liver0.50.61.61.01.01.01.01.00.80.70.70.2-0.51.30.10.2-0.80.80.30.50.0
K content in liver2.01.93.71.71.71.61.91.61.61.91.51.7-1.90.6-0.2-0.10.8-0.9-1.0-1.20.0
Mg content in liver0.20.20.40.50.50.40.60.50.40.40.40.3-0.70.5-0.2-0.20.0-0.0-0.2-0.40.0
Mn content in liver0.20.20.60.2-0.3-0.4-0.3-0.2-0.4-0.6-0.4-0.80.30.6-0.2-0.1-0.80.80.40.40.0
Na content in liver0.70.71.61.31.11.11.01.01.11.21.01.2-0.90.20.20.30.5-0.5-0.4-0.40.0
Rb content in liver0.80.92.8-0.9-0.7-1.1-0.7-1.1-1.4-1.0-1.4-1.7-0.00.3-1.4-1.40.1-0.1-0.6-0.50.0
Se content in liver0.30.31.50.30.80.50.90.70.50.20.5-0.0-0.61.2-0.3-0.2-0.60.60.1-0.00.0
Sr content in liver0.70.61.5-0.2-0.5-0.4-0.8-0.5-0.5-0.9-0.5-0.91.20.20.50.5-1.11.11.11.20.0
Zn content in liver0.30.30.9-0.10.20.40.30.60.5-0.10.70.40.30.60.70.7-1.01.00.90.80.0
Bone: minimum diameter1.63.07.2-2.7-2.5-2.1-2.4-1.9-1.6-2.3-1.3-1.22.6-1.61.00.8-0.70.71.51.40.0
Time in familiar zone, hab. session 10.60.61.5-0.9-1.0-0.9-0.9-0.7-0.6-1.1-0.5-0.41.2-0.70.50.5-0.50.50.80.90.0
Time in novel zone, hab. session 11.21.23.50.3-0.0-0.40.1-0.6-0.90.2-1.1-0.9-1.20.0-1.9-1.81.3-1.4-1.7-1.80.0
Total zone transitions, hab. session 10.10.20.80.0-0.10.00.1-0.00.20.40.20.6-0.1-0.90.20.20.9-0.9-0.4-0.40.0
Total locomotion distance, hab. session 10.30.41.7-0.1-0.3-0.4-0.2-0.4-0.30.3-0.30.2-0.4-1.0-0.5-0.51.3-1.3-1.0-0.90.0
Locomotion velocity, hab. session 10.10.20.80.10.00.00.10.10.30.50.30.7-0.3-0.80.10.10.9-0.9-0.5-0.50.0
Time in familiar zone, hab. session 20.50.51.2-0.3-0.9-0.7-0.9-0.7-0.7-1.1-0.7-1.01.00.10.10.2-0.90.90.80.70.0
Time in novel zone, hab. session 20.10.10.5-0.20.3-0.10.30.0-0.10.1-0.1-0.2-0.60.4-0.6-0.70.2-0.2-0.6-0.50.0
Total zone transitions, hab. session 20.10.10.50.40.40.30.50.30.20.10.2-0.1-0.30.7-0.1-0.1-0.40.5-0.0-0.00.0
Total locomotion distance, hab. session 20.40.51.70.0-0.2-0.6-0.2-0.6-0.9-0.4-1.0-1.1-0.50.4-1.3-1.30.2-0.2-0.9-0.90.0
Locomotion velocity, hab. session 20.20.31.10.1-0.1-0.4-0.1-0.4-0.6-0.2-0.7-0.7-0.50.2-1.0-1.00.4-0.3-0.9-0.80.0
Novel to familiar place preference ratio0.20.30.6-0.8-0.7-0.6-0.7-0.5-0.4-0.7-0.4-0.30.8-0.40.30.3-0.20.20.50.50.0
Novelty place preference0.10.10.3-0.5-0.4-0.4-0.4-0.3-0.2-0.5-0.2-0.20.5-0.30.30.2-0.20.20.40.40.0
Time in novel zone, NPP test0.00.00.2-0.4-0.3-0.3-0.3-0.2-0.2-0.3-0.2-0.20.3-0.10.10.1-0.10.10.20.20.0
Total zone transitions, NPP test0.60.92.50.70.60.50.80.30.31.30.20.7-1.3-0.4-0.8-0.71.6-1.6-1.5-1.60.0
Total locomotion distance, NPP test1.11.54.60.80.3-0.00.4-0.3-0.31.0-0.50.0-1.6-0.6-1.6-1.52.0-2.0-2.1-2.20.0
Locomotion velocity, NPP test0.81.23.80.90.40.20.5-0.00.01.1-0.10.6-1.4-0.8-1.0-1.01.9-1.9-1.8-1.80.0
Intraocular pressure0.50.72.1-0.6-1.0-1.1-1.0-1.1-1.2-1.1-1.3-1.50.70.1-0.6-0.6-0.50.50.20.30.0
Delta distance traveled before/after self-admin0.40.41.1-1.0-0.8-0.6-0.7-0.5-0.5-0.8-0.4-0.61.0-0.20.40.4-0.50.50.90.70.0
Delta ambulatory time before/after self-admin0.10.10.4-0.5-0.1-0.1-0.1-0.0-0.1-0.3-0.1-0.40.40.40.20.2-0.70.70.60.40.0
Parametrial fat weight1.63.710.7-2.4-2.4-1.8-2.6-1.8-1.2-2.2-0.9-0.63.3-2.21.91.8-0.90.92.22.30.0
Pavlov. Cond. lever latency0.70.93.60.3-0.1-0.2-0.10.1-0.3-1.1-0.3-1.30.61.6-0.1-0.0-1.91.91.11.00.0
Pavlov. Cond. magazine entry latency0.20.31.5-0.8-0.5-0.5-0.4-0.5-0.30.0-0.20.30.2-1.20.10.00.9-0.9-0.4-0.30.0
Pavlov. Cond. change in total contacts1.41.46.5-0.7-0.1-0.2-0.1-0.40.01.10.01.2-0.6-2.2-0.2-0.22.5-2.5-1.5-1.50.0
Pavlov. Cond. index score0.60.72.9-0.30.00.10.1-0.10.30.90.31.2-0.4-1.60.20.21.7-1.7-0.9-0.80.0
Pavlov. Cond. latency score0.91.14.00.10.40.50.50.30.71.40.61.6-0.8-1.60.20.22.0-2.0-1.2-1.10.0
Pavlov. Cond. lever contacts0.50.62.7-0.3-0.00.20.0-0.00.40.90.51.3-0.2-1.70.50.51.5-1.5-0.6-0.60.0
Pavlov. Cond. magazine entry number0.20.31.40.70.60.50.50.50.20.10.2-0.3-0.41.2-0.3-0.3-0.70.70.10.10.0
Pavlov. Cond. intertrial magazine entries1.92.36.9-0.2-0.7-1.2-0.9-1.5-1.9-0.7-2.1-1.9-0.90.1-2.6-2.61.2-1.2-1.9-1.80.0
Pavlov. Cond. lever-magazine prob. diff.0.40.52.0-0.20.10.20.20.00.40.90.41.1-0.3-1.40.30.31.4-1.4-0.7-0.70.0
Pavlov. Cond. response bias0.40.52.5-0.8-0.5-0.4-0.4-0.6-0.20.3-0.20.60.0-1.60.00.01.4-1.4-0.7-0.60.0
Pavlov. Cond. lever latency0.91.23.8-0.1-0.5-1.0-0.4-1.0-1.3-0.5-1.5-1.6-0.70.4-1.9-1.90.6-0.6-1.3-1.20.0
Pavlov. Cond. magazine entry latency0.70.82.2-0.10.60.70.50.81.10.51.31.30.5-0.21.51.4-0.50.60.91.20.0
Pavlov. Cond. change in total contacts0.71.13.20.30.91.30.91.21.51.11.61.8-0.0-0.31.51.5-0.10.00.70.60.0
Pavlov. Cond. index score0.91.33.60.00.71.10.71.11.50.81.71.90.5-0.41.91.9-0.30.31.11.10.0
Pavlov. Cond. latency score0.91.23.50.20.91.20.91.31.61.01.71.90.2-0.21.71.7-0.30.30.91.00.0
Pavlov. Cond. lever contacts0.91.23.30.40.71.20.71.21.50.71.61.70.4-0.21.81.8-0.50.51.11.00.0
Pavlov. Cond. magazine entry number0.91.14.00.7-0.2-0.6-0.2-0.7-1.1-0.3-1.3-1.5-1.00.7-2.0-1.90.5-0.5-1.3-1.50.0
Pavlov. Cond. intertrial magazine entries0.20.30.90.3-0.4-0.5-0.4-0.6-0.7-0.5-0.9-0.9-0.10.1-0.9-0.80.2-0.2-0.4-0.60.0
Pavlov. Cond. lever-magazine prob. diff.0.91.23.6-0.10.61.00.61.01.40.81.61.80.5-0.61.91.9-0.20.21.01.10.0
Pavlov. Cond. response bias1.01.34.4-0.10.40.90.40.91.30.41.51.60.9-0.42.12.0-0.70.71.41.50.0
Time in closed arm before self-admin1.21.54.4-0.7-1.3-0.7-1.2-0.4-0.2-1.2-0.00.02.1-0.61.71.7-1.21.22.01.90.0
Time in closed arm after self-admin0.70.71.9-0.6-1.4-0.9-1.1-0.7-0.5-1.1-0.4-0.31.4-0.70.70.7-0.40.41.01.00.0
Time in open arm before self-admin0.20.20.70.3-0.0-0.00.1-0.1-0.10.3-0.0-0.0-0.6-0.3-0.6-0.60.7-0.7-0.9-0.80.0
Time in open arm after self-admin0.40.51.6-0.00.5-0.20.3-0.2-0.50.1-0.6-0.8-0.90.6-1.3-1.30.3-0.3-1.0-1.00.0
Bone: periosteal estimation1.22.66.5-2.5-2.4-2.2-2.3-2.1-1.8-2.0-1.6-1.42.1-1.60.30.1-0.10.10.80.70.0
Bone: periosteal perimeter2.23.89.0-3.0-2.6-2.4-2.5-2.2-2.2-2.8-2.0-2.22.5-0.90.20.1-1.11.11.41.30.0
Bone: post-yield work0.20.30.6-0.2-0.3-0.3-0.2-0.5-0.40.1-0.5-0.2-0.3-0.5-0.6-0.70.8-0.8-0.7-0.80.0
Progressive ratio test 1 active lever presses0.40.62.0-1.1-0.6-0.2-0.6-0.20.2-0.10.51.00.9-1.41.21.10.5-0.50.60.60.0
Progressive ratio test 1 breakpoint0.40.51.8-1.0-0.6-0.3-0.6-0.20.2-0.00.40.90.8-1.41.11.00.5-0.50.50.50.0
Progressive ratio test 1 inactive lever presses1.01.43.3-0.9-1.4-1.2-1.4-0.8-0.8-1.8-0.6-1.01.80.10.60.6-1.61.61.51.50.0
Progressive ratio test 2 active lever presses0.30.41.0-1.0-0.8-0.6-0.8-0.5-0.3-0.8-0.10.01.0-0.60.60.6-0.30.30.70.70.0
Progressive ratio test 2 breakpoint0.30.30.8-0.9-0.7-0.5-0.7-0.4-0.3-0.8-0.10.00.8-0.60.50.5-0.20.20.60.60.0
Progressive ratio test 2 inactive lever presses0.30.41.2-1.0-1.1-1.0-0.9-0.8-0.7-0.9-0.6-0.50.6-0.7-0.1-0.10.1-0.10.10.10.0
Incentive Sensitization - Responses0.00.00.2-0.3-0.2-0.2-0.2-0.2-0.1-0.30.00.20.2-0.40.10.10.2-0.20.00.00.0
Incentive Sensitization - Breakpoint0.00.00.1-0.2-0.1-0.2-0.1-0.1-0.0-0.20.10.10.1-0.30.10.10.2-0.20.00.00.0
Sum of active levers in priming session hrs 5-61.21.23.80.10.9-0.10.7-0.0-0.50.4-0.7-0.9-1.71.1-1.9-2.00.7-0.6-1.7-1.70.0
Progressive ratio0.10.10.6-0.20.30.10.20.0-0.2-0.2-0.3-0.6-0.40.7-0.6-0.6-0.20.2-0.2-0.40.0
Food seeking constrained by brief footshock1.92.37.0-0.8-0.5-1.2-0.5-1.3-1.8-0.6-2.2-2.3-1.00.6-2.6-2.60.7-0.7-1.7-2.00.0
Seeking ratio, punishment vs. effort0.71.02.3-0.3-0.7-1.1-0.6-1.2-1.3-0.3-1.4-1.0-0.4-0.6-1.5-1.51.1-1.0-1.4-1.10.0
Retroperitoneal fat weight1.77.116.3-3.5-3.8-3.6-4.0-3.6-3.1-3.5-2.7-2.03.5-3.20.50.40.3-0.31.21.10.0
Reaction time number correct0.30.61.7-1.0-1.1-1.3-1.1-1.0-0.9-1.1-0.7-0.71.0-0.60.10.1-0.20.20.50.50.0
Reaction time mean minus median0.40.92.80.60.91.21.21.21.41.11.51.7-0.3-0.11.21.10.1-0.10.30.60.0
Reaction time mean minus median AUC0.30.82.00.60.81.11.01.11.30.91.41.4-0.20.11.11.1-0.10.20.40.60.0
Reaction time num false alarms0.20.30.5-0.60.50.40.50.60.60.10.70.50.20.40.70.6-0.60.60.60.60.0
Reaction time num false alarms AUC0.30.40.9-0.30.80.70.90.90.80.50.90.6-0.20.70.60.6-0.60.60.40.40.0
Reaction time trials correct on left0.30.61.7-1.0-1.1-1.3-1.1-1.0-0.9-1.1-0.7-0.71.0-0.60.10.1-0.20.20.50.50.0
Reaction time trials on left0.30.71.7-1.1-1.1-1.3-1.2-1.0-0.8-1.1-0.6-0.61.1-0.70.20.2-0.20.30.60.60.0
Reaction time mean0.61.02.8-0.2-0.10.40.10.50.7-0.30.80.61.10.21.61.5-1.41.41.61.70.0
Reaction time mean AUC0.91.53.50.40.51.10.71.21.40.31.51.20.70.51.91.9-1.41.41.61.70.0
Median of all reaction times0.60.92.7-0.3-0.20.2-0.10.30.3-0.60.40.01.20.51.31.2-1.61.61.61.60.0
Reaction time omissions0.81.24.6-0.8-0.20.6-0.10.51.00.11.21.41.2-0.92.22.1-0.60.51.51.50.0
Reaction time false alarm rate0.20.20.6-0.00.80.80.80.70.60.70.60.5-0.60.40.10.10.1-0.1-0.2-0.20.0
Reaction time premature initiation rate0.60.82.40.60.60.70.80.40.51.30.40.8-1.3-0.5-0.5-0.51.5-1.5-1.3-1.20.0
Reaction time premature initiations0.10.31.2-0.1-0.1-0.00.0-0.10.10.60.10.5-0.3-0.9-0.1-0.11.1-1.1-0.6-0.50.0
Std. dev. reaction times0.40.82.5-0.20.10.60.40.70.90.11.11.10.8-0.21.61.5-0.70.81.11.40.0
Reaction time trials completed0.30.71.7-1.1-1.1-1.3-1.2-1.0-0.8-1.1-0.6-0.61.1-0.70.20.2-0.20.30.60.60.0
Reaction time trials AUC0.50.92.2-1.3-1.3-1.5-1.3-1.1-1.0-1.3-0.8-0.71.3-0.80.20.2-0.30.30.70.70.0
Run reversals in cocaine runway, females1.41.43.3-1.8-1.7-1.5-1.7-1.4-1.2-1.6-0.9-0.91.7-1.20.50.4-0.10.20.71.00.0
Run reversals in cocaine runway, males1.01.02.11.41.41.41.41.41.31.21.31.1-1.01.00.30.3-0.30.3-0.1-0.10.0
Latency to leave start box in cocaine runway0.20.20.9-0.2-0.8-0.6-0.6-0.5-0.3-0.6-0.20.10.5-0.90.20.20.4-0.40.30.10.0
Latency to leave start box in cocaine runway, F0.40.51.5-0.6-1.1-1.0-0.9-1.0-0.8-0.8-0.6-0.30.6-1.2-0.1-0.10.6-0.70.1-0.10.0
Latency to leave start box in cocaine runway, M0.30.20.60.60.50.60.50.70.70.40.80.7-0.10.20.50.6-0.20.20.30.30.0
Std. dev. time between licks in bursts1.31.83.8-1.9-1.9-1.8-1.9-1.9-1.7-1.2-1.6-1.01.2-1.8-0.4-0.40.9-0.9-0.2-0.30.0
Total sessions with >9 infusions1.31.63.7-1.9-1.7-1.5-1.7-1.3-1.1-1.6-0.9-0.91.9-0.90.70.6-0.80.81.21.30.0
Short access day 1 total inactive lever presses1.52.04.6-0.9-2.0-2.1-2.0-1.9-2.0-2.1-1.9-1.91.4-0.6-0.6-0.6-0.40.40.40.50.0
Short access day 10 total inactive lever presses1.02.45.32.31.72.01.82.22.11.42.11.6-0.81.71.11.2-1.21.20.70.70.0
Short access day 1 total infusions2.83.77.6-2.5-2.7-2.7-2.8-2.6-2.5-2.5-2.3-2.02.2-1.8-0.3-0.30.1-0.10.60.60.0
Short access day 10 total infusions1.01.32.9-1.1-1.7-1.7-1.5-1.7-1.6-1.1-1.5-1.20.8-1.2-0.7-0.70.7-0.7-0.3-0.30.0
Short access total infusions0.81.12.5-1.5-1.6-1.4-1.5-1.3-1.1-1.2-0.9-0.61.4-1.40.30.30.2-0.20.50.50.0
Short access day 1 locomotion3.13.98.4-2.3-2.8-2.7-2.9-2.5-2.4-2.6-2.2-2.22.6-1.30.0-0.0-0.70.71.11.30.0
Short access day 10 total locomotion1.52.76.4-2.1-2.3-2.5-2.3-2.1-2.2-2.3-2.0-2.01.7-0.8-0.6-0.6-0.40.40.40.50.0
Short access total locomotion1.61.94.2-2.1-2.0-2.0-2.0-1.8-1.8-1.7-1.6-1.51.5-1.0-0.3-0.3-0.20.20.40.50.0
One hour access (0.3 mA shock)1.01.11.8-1.1-1.0-1.2-0.9-1.3-1.3-0.6-1.3-0.9-0.1-1.0-1.2-1.21.3-1.3-1.0-1.10.0
Compulsive drug intake0.70.81.91.21.31.11.20.70.61.30.30.4-1.40.6-0.7-0.60.7-0.7-1.0-1.00.0
One hour access (shock baseline)1.01.53.8-1.9-1.9-1.7-1.7-1.4-1.3-1.7-1.1-1.01.5-0.90.10.1-0.30.30.70.60.0
Social response proportion3.03.47.7-2.3-1.7-2.3-1.7-2.4-2.6-1.5-2.8-2.50.3-0.8-2.1-2.21.0-1.0-1.4-1.30.0
Social responses2.22.85.7-1.4-1.5-2.0-1.4-2.1-2.2-1.0-2.4-1.9-0.2-1.0-2.2-2.21.6-1.6-1.7-1.70.0
Social time0.40.51.50.60.50.20.3-0.1-0.30.5-0.6-0.5-1.00.5-1.2-1.20.7-0.7-1.2-1.00.0
Soleus weight0.31.06.2-1.2-1.0-0.6-1.1-0.8-0.1-0.10.01.01.1-2.51.21.11.1-1.10.20.00.0
Bone: stiffness1.32.16.7-2.6-2.1-1.9-2.0-1.8-1.5-1.5-1.3-0.91.9-1.90.50.30.2-0.20.60.50.0
Tibialis anterior weight0.10.41.4-0.5-0.8-0.8-1.0-1.0-0.8-0.6-0.7-0.30.7-1.20.0-0.00.5-0.5-0.2-0.00.0
Time to tail flick, vehicle, before self-admin0.20.20.8-0.8-0.4-0.3-0.2-0.3-0.5-0.6-0.5-0.90.20.5-0.3-0.3-0.80.80.10.10.0
Time to tail flick, vehicle, after self-admin0.60.93.30.0-0.1-0.0-0.30.30.2-0.70.5-0.11.00.81.01.0-1.81.81.41.50.0
Time to tail flick, test, before self-admin0.10.20.5-0.7-0.5-0.6-0.4-0.4-0.4-0.6-0.2-0.50.50.00.0-0.0-0.30.30.30.30.0
Time to tail flick, test, after self-admin0.50.51.70.31.20.81.31.00.80.60.70.3-1.11.2-0.3-0.3-0.40.4-0.4-0.40.0
Delta time to tail flick, vehicle, before/after SA0.10.11.01.00.20.20.00.30.3-0.00.40.30.20.30.30.4-0.40.40.40.50.0
Delta time to tail flick, test, before/after SA0.10.10.3-0.00.2-0.00.2-0.0-0.10.1-0.3-0.1-0.50.0-0.5-0.50.3-0.3-0.5-0.60.0
Tibia length0.20.51.7-0.9-1.1-1.0-0.9-0.9-0.7-0.4-0.6-0.10.4-1.3-0.1-0.20.9-0.8-0.4-0.30.0
Ambulatory time before self-admin0.50.72.2-0.3-0.7-0.3-0.7-0.10.3-0.50.61.01.2-1.31.41.50.0-0.01.11.10.0
Ambulatory time after self-admin0.70.92.5-1.2-1.2-0.7-1.2-0.6-0.3-1.0-0.10.11.6-1.01.11.1-0.40.31.31.20.0
Bone: tissue strength0.90.92.70.00.10.50.10.60.8-0.01.00.81.0-0.01.61.6-1.11.11.51.40.0
Total heroin consumption0.70.82.6-0.10.60.90.50.91.20.71.41.60.3-0.31.51.5-0.30.30.80.90.0
Bone: trabecular number3.76.112.4-2.8-3.2-3.4-3.2-3.5-3.5-2.8-3.4-3.01.5-2.0-1.8-1.91.0-1.0-0.8-1.00.0
Bone: trabecular spacing0.91.22.70.91.31.31.31.51.61.11.61.5-0.40.61.21.2-0.60.60.60.80.0
Bone: trabecular thickness2.02.55.1-1.9-1.8-2.0-1.8-2.2-2.3-1.4-2.2-1.80.5-1.3-1.5-1.61.1-1.1-1.0-1.10.0
Bone: trabecular tissue density0.40.61.9-0.00.70.90.70.91.10.91.21.40.1-0.31.21.2-0.00.00.50.50.0
Water consumed over 24 hours0.50.72.6-0.7-0.3-0.4-0.4-0.7-0.40.5-0.40.3-0.4-1.4-0.5-0.61.6-1.6-1.2-1.10.0
Number of responses in last shaping day1.31.42.4-1.2-1.1-1.5-1.1-1.5-1.4-0.5-1.5-0.9-0.0-1.3-1.2-1.31.6-1.6-1.2-1.20.0